I. Joosten

I. Joosten, F. Preijers, D. Eissens, 2010, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

Polymorphisms in CD84, IL12B and TNFAIP3 are associated with response to biologics in patients with psoriasis

M. Coenen, S. Vermeulen, J. Schalkwijk, 2017, The British journal of dermatology.

Rapamycin, and not cyclosporin A, preserves the highly suppressive CD27+ subset of human CD4+CD25+ regulatory T cells.

H. Koenen, I. Joosten, L. Hilbrands, 2006, Blood.

Title Minimum Information about T Regulatory Cells : A Step toward Reproducibility and Standardization Permalink

D. Hafler, J. Bluestone, J. Isaacs, 2018 .

Minimum Information about T Regulatory Cells: A Step toward Reproducibility and Standardization

D. Hafler, J. Bluestone, J. Isaacs, 2018, Front. Immunol..

The number of CCR5 expressing CD4+ T lymphocytes is lower in HIV-infected long-term non-progressors with viral control compared to normal progressors: a cross-sectional study

I. Joosten, A. Indrati, R. van Crevel, 2014, BMC Infectious Diseases.

Peripheral natural killer cytotoxicity and CD56(pos)CD16(pos) cells increase during early pregnancy in women with a history of recurrent spontaneous abortion.

E. Steegers, J. Hendriks, I. Joosten, 2000, Human reproduction.

Iron Status and Systemic Inflammation, but Not Gut Inflammation, Strongly Predict Gender-Specific Concentrations of Serum Hepcidin in Infants in Rural Kenya

H. Tjalsma, M. Zimmermann, I. Joosten, 2013, PloS one.

Cellular sources of IL‐17 in psoriasis: a paradigm shift?

H. Koenen, I. Joosten, P. Kerkhof, 2014, Experimental dermatology.

Foxp3+ regulatory T cells of psoriasis patients easily differentiate into IL-17A-producing cells and are found in lesional skin.

P. van Erp, P. V. D. van de Kerkhof, I. Joosten, 2011, The Journal of investigative dermatology.

Mass Spectrometry for Identification, Monitoring, and Minimal Residual Disease Detection of M-Proteins.

T. Luider, H. Russcher, I. Joosten, 2020, Clinical chemistry.

Evaluation of a new free light chain ELISA assay: bringing coherence with electrophoretic methods

I. Joosten, S. Croockewit, J. Jacobs, 2017, Clinical chemistry and laboratory medicine.

Increased dermal expression of chromatin-associated protein HMGB1 and concomitant T-cell expression of the DNA RAGE in patients with psoriasis vulgaris

H. Koenen, I. Joosten, E. van Rijssen, 2019, Psoriasis.

High mobility group box 1 is increased in the sera of psoriatic patients with disease progression

I. Joosten, A. Sucker, H. Koenen, 2016, Journal of the European Academy of Dermatology and Venereology : JEADV.

BCG Vaccination Induces Long-Term Functional Reprogramming of Human Neutrophils

L. Joosten, M. Netea, G. Pruijn, 2020, Cell reports.

MHC class II (RT1.Bl) binding capacity of autoimmune disease-related T-cell determinants and their sequence analogues in the Lewis rat.

S. Buus, W. van Eden, M. Wauben, 1993, Transplantation proceedings.

Single CD28 stimulation induces stable and polyclonal expansion of human regulatory T cells

H. Koenen, I. Joosten, A. Boots, 2017, Scientific Reports.

Complete sequence analysis of the A*1103 allele.

P. Krausa, I. Joosten, H. Tijssen, 2000, Tissue antigens.

Biomarkers for antimicrobial stewardship: a reappraisal in COVID-19 times?

M. Jaeger, L. Joosten, M. Netea, 2020, Critical Care.

Anakinra treatment in critically ill COVID-19 patients: a prospective cohort study

M. Jaeger, L. Joosten, M. Netea, 2020, Critical Care.

Added effects of dexamethasone and mesenchymal stem cells on early Natural Killer cell activation.

I. Joosten, A. van der Meer, B. van Cranenbroek, 2016, Transplant immunology.

Hormonal stimulation for IVF treatment positively affects the CD56bright/CD56dim NK cell ratio of the endometrium during the window of implantation.

I. Joosten, M. V. van Lierop, J. Bulten, 2004, Molecular human reproduction.

Human secondary lymphoid organs typically contain polyclonally-activated proliferating regulatory T cells.

J. Ijzermans, J. Kwekkeboom, I. Joosten, 2013, Blood.

Burn-Induced Local and Systemic Immune Response: Systematic Review and Meta-Analysis of Animal Studies.

H. Koenen, I. Joosten, R. D. de Vries, 2022, The Journal of investigative dermatology.

Cyclosporine Preserves the Anergic State of Human T Cells Induced by Costimulation Blockade In Vitro

I. Joosten, H. Koenen, E. Fasse, 2005, Transplantation.

Cell Surface Expression of HLA-Cw6 by Human Epidermal Keratinocytes: Positive Regulation by Cytokines, Lack of Correlation to a Variant Upstream of HLA-C.

M. Coenen, J. Schalkwijk, I. Joosten, 2016, The Journal of investigative dermatology.

Changes in peripheral immune cell numbers and functions in octogenarian walkers – an acute exercise study

M. Hopman, T. Eijsvogels, H. Koenen, 2017, Immunity & Ageing.

Complement factor D haplodeficiency is associated with a reduced complement activation speed and diminished bacterial killing

J. Schuurs-Hoeijmakers, I. Joosten, M. van Deuren, 2021, Clinical & translational immunology.

Liver grafts contain a unique subset of natural killer cells that are transferred into the recipient after liver transplantation

E. Kuipers, S. Mancham, J. Kwekkeboom, 2010, Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society.

Superior T-cell suppression by rapamycin and FK506 over rapamycin and cyclosporine A because of abrogated cytotoxic T-lymphocyte induction, impaired memory responses, and persistent apoptosis

I. Joosten, H. Koenen, E. Michielsen, 2003, Transplantation.

The analyses of antigen and DNA polymorphism within the bovine major histocompatibility complex: 1. The class I antigens.

J. Williams, I. Joosten, R. Oliver, 2009, Animal genetics.

Inflammation-associated changes in lipid composition and the organization of the erythrocyte membrane

I. Joosten, P. Pickkers, R. Brock, 2016, BBA clinical.

Antigen-specific regulatory T-cell subsets in transplantation tolerance regulatory T-cell subset quality reduces the need for quantity.

I. Joosten, H. Koenen, 2006, Human immunology.

Humanized Mouse Model of Skin Inflammation Is Characterized by Disturbed Keratinocyte Differentiation and Influx of IL-17A Producing T Cells

P. V. D. van de Kerkhof, I. Joosten, H. Koenen, 2012, PloS one.

Tolerizing Effects of Co-stimulation Blockade Rest on Functional Dominance of CD4+CD25+ Regulatory T Cells

H. Koenen, I. Joosten, L. Hilbrands, 2005, Transplantation.

IL-15 and Cognate Antigen Successfully Expand De Novo-Induced Human Antigen-Specific Regulatory CD4+ T Cells That Require Antigen-Specific Activation for Suppression

I. Joosten, H. Koenen, E. Fasse, 2003, The Journal of Immunology.

Paediatric‐onset psoriasis is associated with ERAP1 and IL23R loci, LCE3C_LCE3B deletion and HLA‐C*06

M. den Heijer, E. D. De Jong, J. Schalkwijk, 2012, The British journal of dermatology.

Following Anti‐CD25 Treatment, A Functional CD4+CD25+ Regulatory T‐Cell Pool Is Present in Renal Transplant Recipients

H. Koenen, I. Joosten, L. Hilbrands, 2007, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

Rapamycin, not cyclosporine, permits thymic generation and peripheral preservation of CD4+CD25+FoxP3+ T cells

L. Boon, H. Koenen, I. Joosten, 2007, Bone Marrow Transplantation.

Stabilizing human regulatory T cells for tolerance inducing immunotherapy.

H. Koenen, I. Joosten, Xuehui He, 2017, Immunotherapy.

Co-culture of healthy human keratinocytes and T-cells promotes keratinocyte chemokine production and RORγt-positive IL-17 producing T-cell populations.

J. Schalkwijk, I. Joosten, J. H. Peters, 2013, Journal of dermatological science.

CD27/CFSE-Based Ex Vivo Selection of Highly Suppressive Alloantigen-Specific Human Regulatory T Cells1

I. Joosten, H. Koenen, E. Fasse, 2005, The Journal of Immunology.

University of Groningen Single CD 28 stimulation induces stable and polyclonal expansion of human regulatory T cells

Xuehui, H. Koenen, I. Joosten, 2017 .

1,25-dihydroxyvitamin D3 modulates cytokine production induced by Candida albicans: impact of seasonal variation of immune responses.

M. Netea, I. Joosten, B. Kullberg, 2011, The Journal of infectious diseases.

Functional consequences of sphingomyelinase-induced changes in erythrocyte membrane structure

J. Fransen, I. Joosten, R. Brock, 2012, Cell Death and Disease.

Mycophenolic Acid‐Mediated Suppression of Human CD4+ T Cells: More Than Mere Guanine Nucleotide Deprivation

I. Joosten, A. Boots, H. Koenen, 2011, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

HLA-C mismatches induce strong cytotoxic T-cell reactivity in the presence of an additional DRB/DQB mismatch and affect NK cell-mediated alloreactivity.

I. Joosten, A. van der Meer, A. Meer, 2001, Transplantation.

Cytotoxic T‐lymphocyte precursor frequency (CTLp‐f) as a tool for distinguishing permissible from non‐permissible class I mismatches in T‐cell‐depleted allogeneic bone marrow transplantation

I. Joosten, T. D. de Witte, A. van der Meer, 2000, British journal of haematology.

The PROCARE consortium: toward an improved allocation strategy for kidney allografts.

M. Bots, J. D. de Fijter, F. V. van Ittersum, 2014, Transplant immunology.

Complete genomic sequence of a novel HLA-B allele, B*4456N.

I. Joosten, H. Tijssen, K. V. van Houwelingen, 2009, Tissue antigens.

Exon 2 sequence analysis of a novel HLA-DRB1 allele, DRB1*1520.

I. Joosten, H. Tijssen, K. V. van Houwelingen, 2006, Tissue antigens.

Exon 2 sequence analysis of a novel HLA-DRB1 allele, DRB1*1460.

I. Joosten, H. Tijssen, K. V. van Houwelingen, 2006, Tissue antigens.

Exon 2 sequence analysis of a novel HLA-DRB1 allele, DRB1*1450.

I. Joosten, H. Tijssen, S. C. van der Zeeuw-Hingrez, 2005, Tissue antigens.

Activation of NK Cells by an Endocytosed Receptor for Soluble HLA-G

Eric O Long, D. Geraghty, I. Joosten, 2005, PLoS biology.

Detection of HLA-G by a specific sandwich ELISA using monoclonal antibodies G233 and 56B.

I. Joosten, M. V. van Lierop, S. Mosselman, 2002, Molecular human reproduction.

Biochemically defined polymorphism of bovine MHC class II antigens

J. Williams, I. Joosten, E. Hensen, 2004, Immunogenetics.

Lymphocyte Isolation from Human Skin for Phenotypic Analysis and Ex Vivo Cell Culture.

H. Koenen, I. Joosten, Xuehui He, 2016, Journal of visualized experiments : JoVE.

Ex vivo expansion of human CD4+ CD25high regulatory T cells from transplant recipients permits functional analysis of small blood samples.

H. Koenen, I. Joosten, L. Hilbrands, 2006, Journal of immunological methods.

The immunosuppressive drug FK 778 induces regulatory activity in stimulated human CD 4 CD 25 T cells

I. Joosten, L. Hilbrands, H. Koenen, 2006 .

Blockade of CD86 and CD40 induces alloantigen-specific immunoregulatory T cells that remain anergic even after reversal of hyporesponsiveness.

H. Koenen, I. Joosten, H. Koenen, 2000, Blood.

Successful Regulatory T Cell-Based Therapy Relies on Inhibition of T Cell Effector Function and Enrichment of FOXP3+ Cells in a Humanized Mouse Model of Skin Inflammation

M. Peppelman, H. Koenen, I. Joosten, 2020, Journal of immunology research.

Translating the role of vitamin D3 in infectious diseases

M. Netea, I. Joosten, A. J. van der Ven, 2012, Critical reviews in microbiology.

Regulation of cytokine responses by seasonality of vitamin D status in healthy individuals

M. Netea, F. Sweep, I. Joosten, 2011, Clinical and experimental immunology.

Allogeneic stimulation of naturally occurring CD4+CD25+ T cells induces strong regulatory capacity with increased donor-reactivity.

H. Koenen, I. Joosten, L. Hilbrands, 2007, Transplant immunology.

Prominent HLA-G Expression in Liver Disease But Not After Liver Transplantation

R. D. de Knegt, P. Boor, S. Mancham, 2015, Transplantation.

Human Regulatory T Cells Highly Suppressive Alloantigen-Specific CD 27 / CFSE-Based Ex Vivo Selection of

H. Koenen, I. Joosten, H. Koenen, 2005 .

Disease inhibition by major histocompatibility complex binding peptide analogues of disease-associated epitopes: more than blocking alone

Angelique T. E. F. Schlief, W. van Eden, M. Wauben, 1992, Journal of Experimental Medicine.

The role of interleukin-1 beta in the pathophysiology of Schnitzler’s syndrome

J. Schalkwijk, H. Koenen, I. Joosten, 2015, Arthritis Research & Therapy.

Direct binding of autoimmune disease related T cell epitopes to purified Lewis rat MHC class II molecules

S. Buus, W. van Eden, L. Pedersen, 1994, International immunology.

A genome-wide functional genomics approach uncovers genetic determinants of immune phenotypes in type 1 diabetes

C. Wijmenga, M. Netea, C. Tack, 2022, eLife.

An Autocrine TNFα–Tumor Necrosis Factor Receptor 2 Loop Promotes Epigenetic Effects Inducing Human Treg Stability In Vitro

H. Koenen, I. Joosten, Xuehui He, 2018, Front. Immunol..

Persistent Systemic Inflammation in Patients With Severe Burn Injury Is Accompanied by Influx of Immature Neutrophils and Shifts in T Cell Subsets and Cytokine Profiles

P. V. van Zuijlen, H. Koenen, I. Joosten, 2021, Frontiers in Immunology.

TNFα-Signaling Modulates the Kinase Activity of Human Effector Treg and Regulates IL-17A Expression

H. Koenen, I. Joosten, R. Smeets, 2020, Frontiers in Immunology.

DNA Methyltransferase Inhibition Promotes Th1 Polarization in Human CD4+CD25high FOXP3+ Regulatory T Cells but Does Not Affect Their Suppressive Capacity

I. Joosten, E. van Rijssen, H. Koenen, 2018, Journal of immunology research.

University of Groningen DNA Methyltransferase Inhibition Promotes Th1 Polarization in Human CD4(+)CD25(high) FOXP3(+) Regulatory T Cells but Does Not Affect Their Suppressive Capacity

I. Joosten, H. Koenen, G. Huls, 2018 .

M. Bots, P. V. D. van der Boog, M. Christiaans, 2018, Front. Immunol..

Polimorphism of bovine MHC class II genes

L. Andersson, J. Poel, N. Cockett, 1994 .

Inhibition of experimental autoimmune encephalomyelitis by MHC class II binding competitor peptides depends on the relative MHC binding affinity of the disease-inducing peptide.

W. van Eden, M. Wauben, I. Joosten, 1994, Journal of immunology.

T-Cell Epitopes Shared Between Immunizing HLA and Donor HLA Associate With Graft Failure After Kidney Transplantation

M. Christiaans, J. D. de Fijter, F. V. van Ittersum, 2021, Frontiers in Immunology.

Differential effects of donor‐specific HLA antibodies in living versus deceased donor transplant

M. Bots, P. V. D. van der Boog, M. Christiaans, 2018, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

Characterization of class I bovine lymphocyte antigens (BoLA) by one-dimensional isoelectrofocusing.

J. Williams, I. Joosten, R. Oliver, 2009, Animal genetics.

Intranasal vaccination with protein bodies elicit strong protection against Streptococcus pneumoniae colonization.

I. Joosten, L. van Niftrik, W. Jong, 2021, Vaccine.

DPB1*7601, a novel DPB1 variant in the Caucasoid population.

I. Joosten, M. Tilanus, E. Rozemuller, 1998, Tissue antigens.

Vitamin D(3) down-regulates proinflammatory cytokine response to Mycobacterium tuberculosis through pattern recognition receptors while inducing protective cathelicidin production.

M. Oosting, M. Netea, I. Joosten, 2011, Cytokine.

Development and Validation of a Multiplex Non-HLA Antibody Assay for the Screening of Kidney Transplant Recipients

M. Bots, M. Christiaans, J. D. de Fijter, 2018, Front. Immunol..

Immunomodulatory aged neutrophils are augmented in blood and skin of psoriasis patients.

M. Netea, E. D. De Jong, H. Koenen, 2021, The Journal of allergy and clinical immunology.

A Novel Bispecific Antihuman CD40/CD86 Fusion Protein with T-cell Tolerizing Potential

P. J. Simons, L. Boon, I. Joosten, 2004, Transplantation.

Molecular pathway profiling of T lymphocyte signal transduction pathways; Th1 and Th2 genomic fingerprints are defined by TCR and CD28-mediated signaling

W. Alkema, W. Fleuren, H. Koenen, 2012, BMC Immunology.

Toward a Sensible Single-antigen Bead Cutoff Based on Kidney Graft Survival

M. Bots, P. V. D. van der Boog, M. Christiaans, 2019, Transplantation.

KIR and Human Leukocyte Antigen Genotype Associated Risk of Cytomegalovirus Disease in Renal Transplant Patients

I. Joosten, L. Hilbrands, A. van der Meer, 2015, Transplantation.

Human CD25Foxp3 regulatory T-cells differentiate into IL-17 producing cells

H. Koenen, I. Joosten, R. Smeets, 2008 .

Human uterine lymphocytes acquire a more experienced and tolerogenic phenotype during pregnancy

I. Joosten, B. van Cranenbroek, D. Feyaerts, 2017, Scientific Reports.

Understanding human immune function using the resources from the Human Functional Genomics Project

Richard A. Notebaart, E. Franzosa, H. Vlamakis, 2016, Nature Medicine.

KIR2DS5 is associated with leukemia free survival after HLA identical stem cell transplantation in chronic myeloid leukemia patients.

I. Joosten, A. van der Meer, B. van Cranenbroek, 2008, Molecular immunology.

Immunological Monitoring of Renal Transplant Recipients to Predict Acute Allograft Rejection Following the Discontinuation of Tacrolimus

H. Koenen, I. Joosten, L. Hilbrands, 2008, PloS one.

Serological definition of bovine MHC class II polymorphism in Holstein-Friesians.

I. Joosten, C. Davies, J. J. van der Poel, 1994, Tissue antigens.

Seasonal Variation in Vitamin D3 Levels Is Paralleled by Changes in the Peripheral Blood Human T Cell Compartment

M. Netea, F. Sweep, I. Joosten, 2012, PloS one.

Soluble HLA-G promotes Th1-type cytokine production by cytokine-activated uterine and peripheral natural killer cells.

I. Joosten, M. V. van Lierop, E. Weiss, 2007, Molecular human reproduction.

THE SPECIFICITY OF ANTI-HLA CLASS II MONOCLONAL ANTIBODIES IN CATTLE.

S. Mikko, I. Joosten, S. Marsh, 1997, European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics.

The influence of MHC polymorphism on the selection of T-cell determinants of FMDV in cattle.

I. Joosten, M. V. van Lierop, J. V. van Noort, 1995, Immunology.

Biochemical characterization of bovine MHC DQ allelic variants by one-dimensional isoelectric focusing.

I. Joosten, W. Davis, E. Hensen, 1994, Tissue antigens.

Determination of the cytotoxic T cell epitopes of mouse hepatitis virus, using elution of viral peptides from class I MHC molecules as an approach.

M. Heemskerk, I. Joosten, C. Boog, 1993, Advances in experimental medicine and biology.

Vaccination against feline immunodeficiency virus using fixed infected cells.

Marian C. Horzinek, I. Joosten, H. Egberink, 1995, Veterinary immunology and immunopathology.

Autoantibody profiles in systemic sclerosis; a comparison of diagnostic tests

W. Alkema, M. Vonk, H. Koenen, 2021, Autoimmunity.

High-dose vitamin D3 supplementation is a requisite for modulation of skin-homing markers on regulatory T cells in HIV-infected patients.

M. Netea, I. Joosten, A. J. van der Ven, 2012, AIDS research and human retroviruses.

Shift in Expression of HLA-G mRNA Spliceforms in Pregnancies Complicated by Preeclampsia

E. Steegers, J. Hendriks, P. Zusterzeel, 2004, The Journal of the Society for Gynecologic Investigation: JSGI.

Diagnostic profiles for precision medicine in systemic sclerosis; stepping forward from single biomarkers towards pathophysiological panels.

W. Alkema, M. Vonk, H. Koenen, 2020, Autoimmunity reviews.

Blood-Based Immune Profiling Combined with Machine Learning Discriminates Psoriatic Arthritis from Psoriasis Patients

W. Alkema, F. V. D. van den Hoogen, E. D. De Jong, 2021, International journal of molecular sciences.

A novel (Leu183Pro-)mutation in the HFE-gene co-inherited with the Cys282Tyr mutation in two unrelated Dutch hemochromatosis patients.

D. Swinkels, C. Jaspers, H. Venselaar, 2008, Blood cells, molecules & diseases.

Platelet microparticles inhibit IL-17 production by regulatory T cells through P-selectin.

I. Joosten, H. Koenen, A. J. van der Ven, 2016, Blood.

1,25‐Dihydroxyvitamin D3 inhibits proliferation but not the suppressive function of regulatory T cells in the absence of antigen‐presenting cells

M. Netea, I. Joosten, H. Koenen, 2011, Immunology.

Natural killer cell reactivity and HLA-G in recurrent spontaneous abortion.

E. Steegers, I. Joosten, W. Nelen, 1999, Transplantation Proceedings.

Fine tuning of antigen-presenting cell-directed monoclonal antibody strategies in the induction of human allospecific T-cell tolerance in vitro.

I. Joosten, H. Koenen, 1998, Transplantation proceedings.

Longitudinal Analysis of T and B Cell Phenotype and Function in Renal Transplant Recipients with or without Rituximab Induction Therapy

H. Koenen, I. Joosten, L. Hilbrands, 2014, PloS one.

Biochemical evidence of the expression of two major histocompatibility complex class I genes on bovine peripheral blood mononuclear cells.

I. Joosten, A. V. D. van der Poel, A. Teale, 2009, Animal genetics.

Involvement of major histocompatibility complex class I compatibility between dam and calf in the aetiology of bovine retained placenta.

I. Joosten, E. Hensen, M. F. Sanders, 2009, Animal genetics.

Bola Polymorphism, Biochemical Analysis at the Product Level

I. Joosten, A. Poel, E. Hensen, 1989 .

The proportion of follicular fluid CD16+CD56DIM NK cells is increased in IVF patients with idiopathic infertility.

I. Joosten, M. V. van Lierop, D. Braat, 2003, Journal of reproductive immunology.

Interferon‐γ‐based mixed lymphocyte culture as a selection tool for allogeneic bone marrow donors other than identical siblings

I. Joosten, A. van der Meer, A. Schattenberg, 1999, British journal of haematology.

Clinical Grade Treg: GMP Isolation, Improvement of Purity by CD127pos Depletion, Treg Expansion, and Treg Cryopreservation

I. Joosten, L. Hilbrands, H. Koenen, 2008, PloS one.

Burn-injured skin is marked by a prolonged local acute inflammatory response of innate immune cells and pro-inflammatory cytokines

P. V. van Zuijlen, H. Koenen, I. Joosten, 2022, Frontiers in Immunology.

Donor and recipient HLA/KIR genotypes do not predict liver transplantation outcome

G. Kazemier, J. Kwekkeboom, I. Joosten, 2011, Transplant international : official journal of the European Society for Organ Transplantation.

Menstrual blood closely resembles the uterine immune micro-environment and is clearly distinct from peripheral blood.

I. Joosten, R. Scholten, B. van Cranenbroek, 2014, Human reproduction.

The number of multinucleated trophoblastic giant cells in the basal decidua is decreased in retained placenta

J. A. van der Laak, I. Joosten, J. Bulten, 2009, Journal of Clinical Pathology.

Intradermal injection of low dose human regulatory T cells inhibits skin inflammation in a humanized mouse model

H. Koenen, I. Joosten, V. L. de Oliveira, 2018, Scientific Reports.

The effects of in vivo B-cell depleting therapy on ex-vivo cytokine production.

S. Smeekens, L. Joosten, M. Netea, 2013, Transplant immunology.

Inhibition of entire myelin basic protein‐induced experimental autoimmune encephalomyelitis in Lewis rats by major histocompatibility complex class II‐binding competitor peptides

Angelique T. E. F. Schlief, W. van Eden, M. Wauben, 1994, European journal of immunology.

Antibodies against ARHGDIB are associated with long‐term kidney graft loss

M. Bots, M. Christiaans, J. D. de Fijter, 2019, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

I. Joosten, T. D. de Witte, A. van der Meer, 2000, British journal of haematology.

CD19 is a useful B cell marker after treatment with rituximab: comment on the article by Jones et al.

H. Koenen, I. Joosten, L. Hilbrands, 2013, Arthritis and rheumatism.

A TNFR2-Agonist Facilitates High Purity Expansion of Human Low Purity Treg Cells

J. van den Dolder, H. Koenen, I. Joosten, 2016, PloS one.

Selective expansion of human natural killer cells leads to enhanced alloreactivity

I. Joosten, F. Preijers, D. Eissens, 2013, Cellular and Molecular Immunology.

Addition of ATG to the conditioning regimen is a major determinant for outcome after transplantation with partially lymphocyte-depleted grafts from voluntary unrelated donors

I. Joosten, F. Preijers, T. Witte, 2004, Bone Marrow Transplantation.

Cytokine Release After Treatment With Rituximab in Renal Transplant Recipients

H. Koenen, I. Joosten, L. Hilbrands, 2015, Transplantation.

Altered phenotype of HLA-G expressing trophoblast and decidual natural killer cells in pathological pregnancies.

E. Steegers, I. Joosten, W. Nelen, 2002, Human reproduction.

Coal tar induces AHR-dependent skin barrier repair in atopic dermatitis.

J. Schalkwijk, I. Joosten, P. Zeeuwen, 2013, The Journal of clinical investigation.

The macrophage mannose receptor induces IL-17 in response to Candida albicans.

Irma Joosten, L. Joosten, M. Netea, 2009, Cell host & microbe.

A 20 acts as master switch in TNFα blockade-driven IL-17 A expression

Raul Aguirre-Gamboa, H. Koenen, I. Joosten, 2017 .

POLYMORPHISM OF BOVINE MHC CLASS I GENES. JOINT REPORT OF THE FIFTH INTERNATIONAL BOVINE LYMPHOCYTE ANTIGEN (BoLA) WORKSHOP, INTERLAKEN, SWITZERLAND, 1 AUGUST 1992

J. A. Stewart, D. Bernoco, H. Lewin, 1994, European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics.

Polymorphism of bovine MHC class I genes. Joint report of the Fifth International Bovine Lymphocyte Antigen (BoLA) Workshop, Interlaken, Switzerland, 1 August 1992.

I. Joosten, G. Ceriotti, C. Davies, 1994, European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics.

Immunoprecipitation and isoelectric focusing of sheep MHC class I antigens reveal higher complexity than serology.

I. Joosten, B. Jugo, B. Amorena, 2002, European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics.

Human CD25highFoxp3pos regulatory T cells differentiate into IL-17-producing cells.

Irma Joosten, Ruben L Smeets, I. Joosten, 2008, Blood.

The Inhibitory FcγIIb Receptor Dampens TLR4-Mediated Immune Responses and Is Selectively Up-regulated on Dendritic Cells from Rheumatoid Arthritis Patients with Quiescent Disease1

P. V. van Riel, G. Adema, W. B. van den Berg, 2009, The Journal of Immunology.

Host and Environmental Factors Influencing Individual Human Cytokine Responses

Richard A. Notebaart, R. Xavier, S. Smeekens, 2016, Cell.

TNF‐&agr;–induced protein 3 (TNFAIP3)/A20 acts as a master switch in TNF‐&agr; blockade–driven IL‐17A expression

Raul Aguirre-Gamboa, H. Koenen, I. Joosten, 2017, The Journal of allergy and clinical immunology.

Chronic HIV infection induces transcriptional and functional reprogramming of innate immune cells

M. Jaeger, R. Horst, L. Joosten, 2021, JCI insight.

Thyrotrophin and thyroxine support immune homeostasis in humans

M. Jaeger, L. Joosten, M. Netea, 2021, Immunology.

Integration of metabolomics, genomics, and immune phenotypes reveals the causal roles of metabolites in disease

R. Xavier, S. Smeekens, M. Jaeger, 2021, Genome biology.

Deconvolution of bulk blood eQTL effects into immune cell subpopulations

Morris A. Swertz, Annique Claringbould, Cisca Wijmenga, 2019, BMC Bioinformatics.

Clonotypic Features of Rearranged Immunoglobulin Genes Yield Personalized Biomarkers for Minimal Residual Disease Monitoring in Multiple Myeloma.

A. Brinkman, B. Scheijen, I. Joosten, 2021, Clinical chemistry.

Selection of self-reactive peptides within human aggrecan by use of a HLA-DRB1*0401 peptide binding motif.

I. Joosten, A. Boots, D. Elewaut, 1997, Journal of autoimmunity.

Immune responses to azacytidine in animal models of inflammatory disorders: a systematic review

H. Koenen, I. Joosten, R. D. de Vries, 2021, Journal of translational medicine.

A Single Dose of Rituximab Does Not Deplete B Cells in Secondary Lymphoid Organs but Alters Phenotype and Function

H. Koenen, I. Joosten, L. Hilbrands, 2013, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

Exploring metal availability in the natural niche of Streptococcus pneumoniae to discover potential vaccine antigens

U. Völker, F. Schmidt, I. Joosten, 2020, Virulence.

Koebner phenomenon in psoriasis is not associated with deletion of late cornified envelope genes LCE3B and LCE3C.

J. Schalkwijk, I. Joosten, P. Zeeuwen, 2012, The Journal of investigative dermatology.

Soluble CD30 does not predict late acute rejection or safe tapering of immunosuppression in renal transplantation.

I. Joosten, L. Hilbrands, B. van Cranenbroek, 2015, Transplant immunology.

How uterine microbiota might be responsible for a receptive, fertile endometrium

I. Joosten, G. Ferwerda, R. G. van der Molen, 2018, Human reproduction update.

Iconography : TNF-?–induced protein 3 (TNFAIP3) /A20 acts as a master switch in TNF-? blockade–driven IL-17A expression

Raul Aguirre-Gamboa, H. Koenen, I. Joosten, 2018 .

Baseline effector cells predict response and NKT cells predict pulmonary toxicity in advanced breast cancer patients treated with everolimus and exemestane.

M. de Boer, C. V. van Herpen, H. Koenen, 2021, International immunopharmacology.

Anaphylaxis from passive transfer of peanut allergen in a blood product.

J. Baumert, E. V. van Pampus, I. Joosten, 2011, The New England journal of medicine.

Natural killer cells and HLA-G expression in the basal decidua of human placenta adhesiva.

I. Joosten, J. Bulten, L. V. van Kempen, 2010, Placenta.

MPZL2, Encoding the Epithelial Junctional Protein Myelin Protein Zero-like 2, Is Essential for Hearing in Man and Mouse.

A. Beynon, P. Lichtner, E. van Wijk, 2018, American journal of human genetics.

Crosstalk between keratinocytes and T cells in a 3D microenvironment: a model to study inflammatory skin diseases.

J. Schalkwijk, I. Joosten, E. van Rijssen, 2014, The Journal of investigative dermatology.

I. Joosten, L. Elving, P. Eldik, 1987 .

Minimum information about tolerogenic antigen-presenting cells (MITAP): a first step towards reproducibility and standardisation of cellular therapies

J. Isaacs, A. ten Brinke, E. Geissler, 2016, PeerJ.

SEROLOGICAL AND BIOCHEMICAL DETECTION OF B‐CELL ANTIGENS IN GOATS

I. Joosten, W. Davis, S. Lazàry, 1993, European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics.

Membrane-bound HLA-G activates proliferation and interferon-gamma production by uterine natural killer cells.

I. Joosten, M. V. van Lierop, S. Mosselman, 2004, Molecular human reproduction.

Monitoring of dynamic changes in Keyhole Limpet Hemocyanin (KLH)-specific B cells in KLH-vaccinated cancer patients

I. Joosten, W. Gerritsen, M. D. de Jonge, 2017, Scientific Reports.

Humoral anti-KLH responses in cancer patients treated with dendritic cell-based immunotherapy are dictated by different vaccination parameters

C. Punt, G. Adema, I. Joosten, 2012, Cancer Immunology, Immunotherapy.

Rituximab as Induction Therapy After Renal Transplantation: A Randomized, Double‐Blind, Placebo‐Controlled Study of Efficacy and Safety

E J Steenbergen, H. Koenen, I. Joosten, 2015, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

KIR Gene and KIR Ligand Analysis to Predict Graft Rejection After Renal Transplantation

I. Joosten, L. Hilbrands, A. van der Meer, 2007, Transplantation.

Differential Effects of Environmental and Genetic Factors on T and B Cell Immune Traits

R. Xavier, S. Smeekens, M. Jaeger, 2016, Cell reports.

Limited Amounts of Dendritic Cells Migrate into the T-Cell Area of Lymph Nodes but Have High Immune Activating Potential in Melanoma Patients

W. Oyen, C. Figdor, C. Punt, 2009, Clinical Cancer Research.

How can we reduce costs of solid‐phase multiplex‐bead assays used to determine anti‐HLA antibodies?

M. Bots, P. V. D. van der Boog, M. Christiaans, 2016, HLA.

Analysis of 127 Stem Cell Donations of the Regional Bone Marrow Donor Bank Europdonor Nijmegen, The Netherlands

I. Joosten, F. Preijers, A. Schattenberg, 2003, Leukemia & lymphoma.

Allocation to highly sensitized patients based on acceptable mismatches results in low rejection rates comparable to nonsensitized patients

M. Bots, M. Christiaans, D. Roelen, 2019, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

Bimodal Targeting of Human Leukocytes by Fc- and CpG-Decorated Polymersomes to Tune Immune Induction

J. V. van Hest, I. Joosten, M. D. de Jonge, 2021, Biomacromolecules.

A single [3H]thymidine-based limiting dilution analysis to determine HTLp and CTLp frequencies for bone marrow donor selection

I. Joosten, A. Meer, W. Allebes, 1997, Bone Marrow Transplantation.

Clusters of Tolerogenic B Cells Feature in the Dynamic Immunological Landscape of the Pregnant Uterus.

I. Joosten, G. Ferwerda, D. Feyaerts, 2020, Cell reports.

Long-Term Effects of Experimental Human Endotoxemia on Immune Cell Function: Similarities and Differences With Sepsis

I. Joosten, P. Pickkers, M. Kox, 2019, Shock.

Heritable and non-heritable genetic effects on retained placenta in Meuse-Rhine-Yssel cattle.

I. Joosten, A. Koets, L. Benedictus, 2013, Animal reproduction science.

Bovine MHC class II restriction fragment length polymorphism linked to expressed polymorphism

L. Andersson, I. Joosten, E. Hensen, 2004, Immunogenetics.

Levels of soluble HLA-G in amniotic fluid are related to the sex of the offspring.

E. Steegers, I. Joosten, M. V. van Lierop, 2003, European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics.

Pregnancy and neonatal outcomes in women with immune mediated inflammatory diseases exposed to anti-tumor necrosis factor-α during pregnancy: A systemic review and meta-analysis.

E. D. De Jong, I. Joosten, F. Hoentjen, 2021, Journal of autoimmunity.

Maternal, Decidual, and Neonatal Lymphocyte Composition Is Affected in Pregnant Kidney Transplant Recipients

I. Joosten, B. van Cranenbroek, A. Lely, 2021, Frontiers in Immunology.

The Presence of Donor-Specific Human Leukocyte Antigen Antibodies Does Not Preclude Successful Withdrawal of Tacrolimus in Stable Renal Transplant Recipients

I. Joosten, L. Hilbrands, W. Allebes, 2007, Transplantation.

Effect of initial immunosuppression on long-term kidney transplant outcome in immunological low-risk patients.

M. Bots, P. V. D. van der Boog, M. Christiaans, 2018, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

Molecular pathway profiling of T lymphocyte signal transduction pathways; Th1 and Th2 genomic fingerprints are defined by TCR and CD28-mediated signaling

W. Alkema, W. Fleuren, H. Koenen, 2012, BMC Immunology.

DNA-PKcs Controls an Endosomal Signaling Pathway for a Proinflammatory Response by Natural Killer Cells

Irma Joosten, Mark W. Moyle, Sumati Rajagopalan, 2010, Science Signaling.

Helper and cytotoxic T cell precursor frequencies are not predictive for development of acute graft-versus-host disease after partially T cell-depleted HLA-identical sibling BMT

I. Joosten, A. Meer, A. Schattenberg, 1998, Bone Marrow Transplantation.

Metabolic Pathways Involved in Regulatory T Cell Functionality

I. Joosten, H. Koenen, Xuehui He, 2019, Front. Immunol..

High Log-Scale Expansion of Functional Human Natural Killer Cells from Umbilical Cord Blood CD34-Positive Cells for Adoptive Cancer Immunotherapy

I. Joosten, T. D. de Witte, F. Preijers, 2010, PloS one.

The Inhibitory FcγIIb Receptor Dampens Toll-like Receptor 4 Mediated Immune Responses and is Selectively Up Regulated on Dendritic Cells from Rheumatoid Arthritis Patients with Quiescent Disease

H. Koenen, I. Joosten, T. Radstake, 2009 .

Immune responses to stress after stress management training in patients with rheumatoid arthritis

T. Radstake, F. Kraaimaat, P. V. van Riel, 2013, Arthritis Research & Therapy.

Balance of Treg vs. T‐helper cells in the transition from symptomless to lesional psoriatic skin

P. V. D. van de Kerkhof, I. Joosten, H. Koenen, 2013, The British journal of dermatology.

Definition of an extended MHC class II-peptide binding motif for the autoimmune disease-associated Lewis rat RT1.BL molecule.

M. Wauben, I. Joosten, I Joosten, 1997, International immunology.

CHARACTERIZATION OF BOVINE MHC CLASS II POLYMORPHISM USING THREE TYPING METHODS: SEROLOGY, RFLP AND IEF

L. Andersson, P. Mariani, I. Joosten, 1992, European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics.

COVID-19 patients exhibit less pronounced immune suppression compared with bacterial septic shock patients

M. Jaeger, L. Joosten, M. Netea, 2020, Critical Care.

Human Cytomegalovirus Infection Increases Both Antibody- and Non–Antibody-Dependent Cellular Reactivity by Natural Killer Cells

F. Claas, I. Joosten, A. van der Meer, 2017, Transplantation direct.

Eculizumab impairs Neisseria meningitidis serogroup B killing in whole blood despite 4CMenB vaccination of PNH patients.

I. Joosten, M. D. de Jonge, S. Langemeijer, 2020, Blood advances.

Quantitative measurement of immunoglobulins and free light chains using mass spectrometry.

T. Luider, U. Engelke, R. Wevers, 2015, Analytical chemistry.

The bovine major histocompatibility complex. A biochemical characterization of its products and their role in the etiology of retained placenta.

I. Joosten, 1990 .

In Vitro Effects of Rituximab on the Proliferation, Activation and Differentiation of Human B Cells

L. Boon, I. Joosten, L. Hilbrands, 2012, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

Retained placenta: an immunological approach

I. Joosten, E. Hensen, 1992 .

Factors affecting occurrence of retained placenta in cattle. Effect of sire on incidence

I. Joosten, L. Elving, P. Eldik, 1991 .

Low-affinity TCR engagement drives IL-2-dependent post-thymic maintenance of naive CD4+ T cells in aged humans

B. Kroesen, I. Joosten, A. Boots, 2015, Aging cell.

Genetic and environmental effects on the immune phenotypes in type 1 diabetes

C. Wijmenga, M. Netea, C. Tack, 2021, medRxiv.

The immunosuppressive drug FK778 induces regulatory activity in stimulated human CD4+ CD25- T cells.

H. Koenen, I. Joosten, L. Hilbrands, 2007, Blood.

Gateway to understanding microparticles: standardized isolation and identification of plasma membrane-derived vesicles.

I. Joosten, R. Brock, G. Bosman, 2013, Nanomedicine.

HLA-DRB1*12 is associated with protection against complicated typhoid fever, independent of tumour necrosis factor alpha.

E. Dharmana, I. Joosten, J. V. D. van der Meer, 2002, European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics.

Endometrial natural killer (NK) cells reveal a tissue-specific receptor repertoire

I. Joosten, A. van der Meer, B. van Cranenbroek, 2018, Human reproduction.

BCG-induced trained immunity enhances acellular pertussis vaccination responses in an explorative randomized clinical trial

M. Huynen, M. Netea, I. Joosten, 2022, NPJ vaccines.

A systems approach to inflammation identifies therapeutic targets in SARS-CoV-2 infection

L. Joosten, M. Netea, C. Maas, 2020, medRxiv.

Title: N-linked glycosylation of the M-protein variable region: Glycoproteogenomics reveals a new layer of personalized complexity in multiple myeloma. Running title: M-protein glycosylation in Multiple Myeloma Authors

I. Joosten, D. Lefeber, M. Vanduijn, 2023 .

Phosphatidylserine exposure on stored red blood cells as a parameter for donor-dependent variation in product quality.

M. Peppelman, F. Atsma, I. Joosten, 2014, Blood transfusion = Trasfusione del sangue.

Antibiotic Intervention Affects Maternal Immunity During Gestation in Mice

J. Garssen, I. Joosten, G. Ferwerda, 2021, Frontiers in Immunology.

The gut microbiome as mediator between diet and its impact on immune function

M. Jaeger, R. Horst, L. Joosten, 2021, Scientific Reports.

Seasonal and Nonseasonal Longitudinal Variation of Immune Function

S. Smeekens, M. Jaeger, L. Joosten, 2021, The Journal of Immunology.

Multiple Myeloma Minimal Residual Disease Detection: Targeted Mass Spectrometry in Blood vs Next-Generation Sequencing in Bone Marrow.

T. Luider, I. Joosten, J. Corre, 2021, Clinical chemistry.

In vivo induction of cutaneous inflammation results in the accumulation of extracellular trap-forming neutrophils expressing RORγt and IL-17.

P. V. D. van de Kerkhof, I. Joosten, H. Koenen, 2014, The Journal of investigative dermatology.

Pretransplant C3d-Fixing Donor-Specific Anti-HLA Antibodies Are Not Associated with Increased Risk for Kidney Graft Failure.

M. Bots, P. V. D. van der Boog, M. Christiaans, 2018, Journal of the American Society of Nephrology : JASN.

The Architecture of Circulating Immune Cells Is Dysregulated in People Living With HIV on Long Term Antiretroviral Treatment and Relates With Markers of the HIV-1 Reservoir, Cytomegalovirus, and Microbial Translocation

M. Jaeger, L. Joosten, M. Netea, 2021, Frontiers in Immunology.

Dysregulated innate and adaptive immune responses discriminate disease severity in COVID-19.

L. Joosten, M. Netea, C. Maas, 2021, The Journal of infectious diseases.

Ex Vivo Generation of Human Alloantigen-Specific Regulatory T Cells from CD4posCD25high T Cells for Immunotherapy

H. Koenen, I. Joosten, L. Hilbrands, 2008, PloS one.

Amniotic fluid soluble human leukocyte antigen G is markedly decreased in offspring with neural tube defects.

E. Steegers, R. Steegers-Theunissen, I. Joosten, 2002, Early human development.

Immune responses to stress in rheumatoid arthritis and psoriasis.

F. Kraaimaat, P. V. van Riel, A. Donders, 2014, Rheumatology.

A combination of immune cell types identified through ensemble machine learning strategy detects altered profile in recurrent pregnancy loss: a pilot study.

I. Joosten, G. Ferwerda, D. Feyaerts, 2022, F&S science.

POLYMORPHISM OF BOVINE MHC CLASS II GENES. JOINT REPORT OF THE FIFTH INTERNATIONAL BOVINE LYMPHOCYTE ANTIGEN (BOLA) WORKSHOP, INTERLAKEN, SWITZERLAND, 1 AUGUST 1992

L. Andersson, S. Mikko, H. Lewin, 1994 .

Prostaglandin catabolism in the bovine placenta.

I. Joosten, M. Keirse, J. Erwich, 1988, Placenta.

Prior exposure to B. pertussis shapes the mucosal antibody response to acellular pertussis booster vaccination

M. Huynen, P. Šebo, I. Joosten, 2022, Nature Communications.

Umbilical cord-mesenchymal stem cells induce a memory phenotype in CD4+ T cells

I. Joosten, M. D. de Jonge, T. Wolfs, 2023, Frontiers in Immunology.

Targeting PKC in human T cells using sotrastaurin (AEB071) preserves regulatory T cells and prevents IL-17 production.

P. V. D. van de Kerkhof, H. Koenen, I. Joosten, 2014, The Journal of investigative dermatology.

A paired kidney analysis on the impact of pre-transplant anti-HLA antibodies on graft survival.

M. Bots, P. V. D. van der Boog, M. Christiaans, 2018, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

Quiescent Disease from Rheumatoid Arthritis Patients with Selectively Up-regulated on Dendritic Cells TLR4-Mediated Immune Responses and Is IIb Receptor Dampens g The Inhibitory Fc

G. Adema, H. Koenen, I. Joosten, 2009 .

Use of isoelectric focusing to define major histocompatibility complex class I polymorphism in goats.

I. Joosten, E. Hensen, M. F. Sanders, 2009, Animal Genetics.

A higher BMI is not associated with a different immune response and disease course in critically ill COVID-19 patients

M. Jaeger, L. Joosten, M. Netea, 2021, International Journal of Obesity.

Balance of Treg versus T‐effector cells during systemic treatment with adalimumab and topical treatment with calcipotriol–betamethasone dipropionate ointment

H. Koenen, I. Joosten, P. Kerkhof, 2015, Experimental dermatology.

Rho kinase inhibitor Y-27632 prolongs the life span of adult human keratinocytes, enhances skin equivalent development, and facilitates lentiviral transduction.

P. Jansen, J. Schalkwijk, I. Joosten, 2012, Tissue engineering. Part A.

Redefining Strategies to Introduce Tolerance-Inducing Cellular Therapy in Human beings to Combat Autoimmunity and Transplantation Reactions

Anja ten Brinke, Irma Joosten, S. Marieke van Ham, 2014, Front. Immunol..