J. Leggo

发表

Phenotypic characterization of individuals with 30-40 CAG repeats in the Huntington disease (HD) gene reveals HD cases with 36 repeats and apparently normal elderly individuals with 36-39 repeats.

P S Harper, D Curtis, S. Folstein, 1996, American journal of human genetics.

The Canadian "National Program for hemophilia mutation testing" database: a ten-year review.

J. Leggo, P. James, D. Lillicrap, 2013, American journal of hematology.

Non-Mendelian transmission at the Machado-Joseph disease locus in normal females: preferential transmission of alleles with smaller CAG repeats.

D. Rubinsztein, J. Leggo, 1997, Journal of medical genetics.

Microsatellites evolve more rapidly in humans than in chimpanzees.

D. Rubinsztein, W. Amos, J. Leggo, 1995, Genomics.

Frequencies of "grey-zone" and premutation-size FMR1 CGG-repeat alleles in patients with developmental disability in Cyprus and Canada.

C. Sismani, P. Patsalis, J. Leggo, 1999, American journal of medical genetics.

The mutational spectrum of type 1 von Willebrand disease: Results from a Canadian cohort study.

L. O'Brien, J. Leggo, M. Othman, 2007, Blood.

Intensive exposure to factor VIII is a risk factor for inhibitor development in mild hemophilia A

V. Blanchette, M. Carcao, J. Leggo, 2003, Journal of thrombosis and haemostasis : JTH.

Haplotype analysis of the delta 2642 and (CAG)n polymorphisms in the Huntington's disease (HD) gene provides an explanation for an apparent 'founder' HD haplotype.

D. Rubinsztein, D. Barton, M. Ferguson-Smith, 1995, Human molecular genetics.

Homozygotes and heterozygotes for ciliary neurotrophic factor null alleles do not show earlier onset of Huntington's disease

D. Rubinsztein, D. Craufurd, J. Leggo, 1997, Neurology.

Analysis of polyglutamine-coding repeats in the TATA-binding protein in different human populations and in patients with schizophrenia and bipolar affective disorder.

T. Crow, L. DeLisi, E. Paykel, 1996, American journal of medical genetics.

Frequency of Platelet type versus Type 2B von Willebrand Disease

M. Ozelo, J. Leggo, M. Othman, 2011, Thrombosis and Haemostasis.

Analysis of thirteen trinucleotide repeat loci as candidate genes for schizophrenia and bipolar affective disorder.

T. Crow, L. DeLisi, C. Ross, 1996, American journal of medical genetics.

The genetics of Canadian type 3 von Willebrand disease: further evidence for co‐dominant inheritance of mutant alleles

V. Blanchette, J. Leggo, P. James, 2013, Journal of thrombosis and haemostasis : JTH.

The Canadian “National Program for hemophilia mutation testing” database: A ten‐year review

J. Leggo, P. James, D. Lillicrap, 2013, American journal of hematology.

Myotonic dystrophy CTG repeats and the associated insertion/deletion polymorphism in human and primate populations.

D. Rubinsztein, D. Barton, M. Ferguson-Smith, 1994, Human molecular genetics.

Aminoglycoside suppression of nonsense mutations in severe hemophilia.

J. Leggo, P. James, D. Lillicrap, 2005, Blood.

Different clinical phenotype in triplets with haemophilia A

M. Carcao, J. Leggo, D. Lillicrap, 2007, Haemophilia : the official journal of the World Federation of Hemophilia.

Genetic linkage and association analysis in type 1 von Willebrand disease: results from the Canadian Type 1 VWD Study

A. Paterson, L. O'Brien, J. Leggo, 2006, Journal of thrombosis and haemostasis : JTH.

cDNA cloning of a human homologue of the Caenorhabditis elegans cell fate-determining gene mab-21: expression, chromosomal localization and analysis of a highly polymorphic (CAG)n trinucleotide repeat.

T. Crow, F. McMahon, L. DeLisi, 1996, Human molecular genetics.

Microsatellite evolution — evidence for directionality and variation in rate between species

C. Ross, D. Rubinsztein, M. Ferguson-Smith, 1995, Nature Genetics.

Genetic association between monoamine oxidase A microsatellite and RFLP alleles and bipolar affective disorder: analysis and meta-analysis.

E. Paykel, D. Rubinsztein, J. Leggo, 1996, Human molecular genetics.

Patients with features similar to Huntington's disease, without CAG expansion in huntingtin

J. Hodges, C. Ross, D. Rubinsztein, 1998, Neurology.

Sequence variation and size ranges of CAG repeats in the Machado-Joseph disease, spinocerebellar ataxia type 1 and androgen receptor genes.

M A Ferguson-Smith, R A Irvine, G. Coetzee, 1995, Human molecular genetics.

Mutational bias provides a model for the evolution of Huntington's disease and predicts a general increase in disease prevalence

Ronald Bontrop, David E. Barton, William Amos, 1994, Nature Genetics.

Site of (CCG) polymorphism in the HD gene

D. Rubinsztein, D. Barton, M. Ferguson-Smith, 1993, Nature Genetics.

Analysis of spinocerebellar ataxia types 1, 2, 3, and 6, dentatorubral-pallidoluysian atrophy, and Friedreich's ataxia genes in spinocerebellar ataxia patients in the UK.

D. Rubinsztein, A. Dalton, M. Kotze, 1997, Journal of medical genetics.

A case of non‐resolving hemophilia B Leyden in a 42‐year‐old male (F9 promoter + 13 A>G)

J. Leggo, P. James, D. Lillicrap, 2008, Journal of thrombosis and haemostasis : JTH.

B37 repeats are normal in most schizophrenic patients

T. Crow, L. DeLisi, D. Rubinsztein, 1994, British Journal of Psychiatry.

Dentatorubral and pallidoluysian atrophy (DRPLA) Clinical and neuropathological findings in genetically confirmed north american and european pedigrees

M. Porteous, M. Wagster, N. Ranen, 1997, Movement disorders : official journal of the Movement Disorder Society.

Genetic diversity at the FMR1 locus in the Indonesian population

J. Leggo, S. Faradz, M. Buckley, 2000, Annals of human genetics.

Analysis of the 5' upstream sequence of the Huntington's disease (HD) gene shows six new rare alleles which are unrelated to the age at onset of HD.

D. Rubinsztein, J. Leggo, R. Coles, 1997, Journal of medical genetics.

Genotypes at the GluR6 kainate receptor locus are associated with variation in the age of onset of Huntington disease.

G Norbury, D. Rubinsztein, D. Craufurd, 1997, Proceedings of the National Academy of Sciences of the United States of America.

DNA microarray analysis for the detection of mutations in hemophilia A

H. Feilotter, J. Leggo, D. Lillicrap, 2006, Journal of thrombosis and haemostasis : JTH.

Distribution of FMR1 and FMR2 alleles in Javanese individuals with developmental disability and confirmation of a specific AGG‐interruption pattern in Asian populations

J. Leggo, S. Faradz, M. Buckley, 2001 .

A Founder Factor VII Mutation, Valine 2016 to Alanine, in a Population with an Extraordinarily High Prevalence of Mild Hemophilia A

J. Leggo, D. Lillicrap, M. Scully, 2002, Thrombosis and Haemostasis.

Study of the Huntington's disease (HD) gene CAG repeats in schizophrenic patients shows overlap of the normal and HD affected ranges but absence of correlation with schizophrenia.

T. Crow, L. DeLisi, D. Rubinsztein, 1994, Journal of medical genetics.

Improved amplification of the FMR2 GCC repeat from dried blood spots.

J. Leggo, J. Holden, 1999, American journal of medical genetics.

Normal CAG and CCG repeats in the Huntington's disease genes of Parkinson's disease patients.

D. Rubinsztein, D. Barton, M. Ferguson-Smith, 1995, American journal of medical genetics.