C. Melia

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An analysis of the surface chemical structure of polymethacrylate (Eudragit) film coating polymers by XPS

M. Davies, I. Wilding, J. Watts, 1989 .

Review article: mechanisms of drug release from tablets and capsules. 2. Dissolution

S. Davis, C. Melia, 1989, Alimentary pharmacology & therapeutics.

Pharmaceutical applications of confocal laser scanning microscopy: the physical characterisation of pharmaceutical systems.

Peter Timmins, C. Melia, P. Timmins, 2007, Advanced drug delivery reviews.

Elucidation of the internal physical and chemical microstructure of pharmaceutical granules using X-ray micro-computed tomography, Raman microscopy and infrared spectroscopy.

Clive J Roberts, Andrew Parker, C. Roberts, 2010, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

FT RAMAN SPECTROSCOPY OF DRUGS IN POLYMERS

M. Davies, C. Melia, P. Hendra, 1990 .

Fourier Transform-Raman Spectroscopy for the Qualitative and Quantitative Characterization of Sulfasalazine-Containing Polymeric Microspheres

M. Davies, C. Melia, P. Hendra, 1991, Pharmaceutical Research.

Use of the Dynamic Gastric Model as a tool for investigating fed and fasted sensitivities of low polymer content hydrophilic matrix formulations.

C. Melia, S. Chessa, D. Storey, 2016, International journal of pharmaceutics.

Microencapsulation using emulsification/solvent evaporation: an overview of techniques and applications.

C. Melia, P. Watts, M. Davies, 1990, Critical reviews in therapeutic drug carrier systems.

First order release rate from porous PLA microspheres with limited exit holes on the exterior surface.

C. Washington, C. Melia, T. Ehtezazi, 2000, Journal of controlled release : official journal of the Controlled Release Society.

Drug release from HPMC matrices in milk and fat-rich emulsions.

D. Barrett, C. Melia, H. Williams, 2011, Journal of pharmaceutical sciences.

Natural Polysaccharides in Hydrophilic Matrices

C. Melia, P. Timmins, 2014 .

Molecular and mechanical properties of hydroxypropyl methylcellulose solutions during the sol:gel transition

C. Melia, C. Sammon, P. Timmins, 2009 .

The application of attenuated total reflectance Fourier transform infrared spectroscopy to monitor the concentration and state of water in solutions of a thermally responsive cellulose ether during gelation

C. Melia, C. Sammon, P. Timmins, 2006 .

Monitoring the Thermal Gelation of Cellulose Ethers in situ Using Attenuated Total Reflectance Fourier Transform Infrared Spectroscopy

C. Melia, C. Sammon, P. Timmins, 2005, Applied spectroscopy.

Dielectric characterisation of sodium alginate gels

J. Newton, M. Davies, C. Melia, 1992 .

The suitability of tris(hydroxylmethyl) aminomethane (THAM) as a buffering system for hydroxypropyl methylcellulose (HPMC) hydrophilic matrices containing a weak acid drug.

C. Melia, P. Timmins, S. Pygall, 2010, International journal of pharmaceutics.

Characterising drug release processes within controlled release dosage forms using the confocal laser scanning microscope

M. Davies, C. Melia, S. Hibberd, 1996 .

High Resolution Imaging of Starch Granule Surfaces by Atomic Force Microscopy

M. Davies, P. M. Baldwin, C. Melia, 1998 .

Review article: mechanisms of drug release from tablets and capsules. I: Disintegration

S. Davis, C. Melia, S. Davis, 1989, Alimentary pharmacology & therapeutics.

The analysis of biomedical poly(ortho esters) by near-IR Fourier transform Raman spectroscopy

M. Davies, C. Melia, J. Heller, 1993 .

The in-situ chemical analysis of polymer film coatings using static secondary ion mass spectrometry (SSIMS)

M. Davies, R. Rowe, I. Wilding, 1990 .

SSIMS analysis of methacrylate copolymers employed in drug delivery

M. Davies, I. Wilding, R. Short, 1990 .

Compression and compaction properties of plasticised high molecular weight hydroxypropylmethylcellulose (HPMC) as a hydrophilic matrix carrier.

C. Melia, I. Hardy, W. Cook, 2006, International journal of pharmaceutics.

The effect of sucrose and salts in combination on the drug release behaviour of an HPMC matrix.

C. Melia, H. Williams, R. Ward, 2010, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

The extended release properties of HPMC matrices in the presence of dietary sugars.

C. Melia, H. Williams, R. Ward, 2009, Journal of controlled release : official journal of the Controlled Release Society.

Radiolabelling of polymer microspheres for scintigraphic investigations by neutron activation. 1. Incorporation of samarium oxide and its effects on the properties of Eudragit RS: sulphasalazine microspheres

Clive G. Wilson, M. Davies, C. Melia, 1991 .

Encapsulation of 5-aminosalicylic acid into Eudragit RS microspheres and modulation of their release characteristics by use of surfactants

M. Davies, C. Melia, P. Watts, 1991 .

The surface chemistry of starch granules studied by time-of-flight secondary ion mass spectrometry

M. Davies, P. M. Baldwin, C. Melia, 1997 .

A liquid chromatography method for quantifying caffeine dissolution from pharmaceutical formulations into colloidal, fat-rich media.

D. Barrett, C. Melia, H. Williams, 2010, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Uptake of drugs by catheters: the influence of the drug molecule on sorption by polyurethane catheters.

M C Davies, M. Davies, C. Melia, 1996, Biomaterials.

Transdermal delivery of theophylline to premature infants using a hydrogel disc system.

N. Rutter, P. Cartlidge, S. Davis, 1990, British journal of clinical pharmacology.

Xanthan/locust bean gum interactions at room temperature.

S. Hill, C. Melia, B. Launay, 1992 .

The Qualitative and Quantitative Analysis of Chlorpropamide Polymorphic Mixtures by Near-Infrared Fourier Transform Raman Spectroscopy

M. Davies, C. Melia, P. Hendra, 1993, Pharmaceutical Research.

Solution interactions of diclofenac sodium and meclofenamic acid sodium with hydroxypropyl methylcellulose (HPMC).

P. Griffiths, C. Melia, B. Wolf, 2011, International journal of pharmaceutics.

Hydrophilic Matrix Tablets for Oral Controlled Release

Peter Timmins, C. Melia, P. Timmins, 2014, AAPS Advances in the Pharmaceutical Sciences Series.

The analysis of biomedical hydroxyapatite powders and hydroxyapatite coatings on metallic medical implants by near-IR Fourier transform Raman spectroscopy

M. Davies, C. Melia, G. Hastings, 1993 .

Fourier transform Raman spectroscopy of polymeric biomaterials and drug delivery systems

M. Davies, C. Melia, D. Bourgeois, 1990 .

Hydrophilic Matrix Dosage Forms: Definitions, General Attributes, and the Evolution of Clinical Utilization

C. Melia, P. Timmins, S. Pygall, 2014 .

The influence of substituted phenols on the sol:gel transition of hydroxypropyl methylcellulose (HPMC) aqueous solutions.

C. Melia, P. Timmins, S. Doughty, 2014, Carbohydrate polymers.

Determination of the internal morphology of poly (D,L-lactide) microspheres using stereological methods.

C. Washington, C. Melia, T. Ehtezazi, 1999, Journal of controlled release : official journal of the Controlled Release Society.

A concentric cylinder shear device for the study of stability in intravenous emulsions.

C. Washington, C. Melia, jihong Han, 2004, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

The influence of l-amino acid molecular structure on the phase transition temperature of hydroxypropyl methylcellulose

C. Melia, S. Doughty, R. Macrae, 2006 .

Strand-like phase separation in mixtures of xanthan gum with anionic polyelectrolytes

C. Melia, I. Jolliffe, F. Hampson, 2009 .

Scintigraphic demonstration of lactulose-induced accelerated proximal colon transit.

R. Spiller, M. Davies, C. Melia, 1992, Gastroenterology.

Structure and behaviour in hydrophilic matrix sustained release dosage forms: 3. The influence of pH on the sustained-release performance and internal gel structure of sodium alginate matrices

Martyn C. Davies, John R. Mitchell, M. Davies, 1995 .

Magnetic Resonance Imaging Analysis of Molecular Mobility during Dissolution of Poly(vinyl alcohol) in Water

Stephen P. Morgan, Balaji Narasimhan, Richard Bowtell, 1999 .

Self-diffusion and molecular mobility in PVA-based dissolution-controlled systems for drug delivery.

R Bowtell, N A Peppas, R. Bowtell, 1998, Magnetic resonance imaging.

Starch granule surface imaging using low-voltage scanning electron microscopy and atomic force microscopy.

M. Davies, P. M. Baldwin, C. Melia, 1997, International journal of biological macromolecules.

Oesophageal bioadhesion of sodium alginate suspensions 2. Suspension behaviour on oesophageal mucosa.

C. Melia, F. Hampson, P. Dettmar, 2005, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

A Simple and Rapid Method for the Quantification of Eudragit RS100 and RL100 Poly(methacrylates) in Sustained-Release Dosage Forms

K. A. Khan, I. Wilding, C. Melia, 1991, Pharmaceutical Research.

Mechanisms of drug release in citrate buffered HPMC matrices.

C. Melia, P. Timmins, S. Pygall, 2009, International journal of pharmaceutics.

In Vitro Physical and Imaging Techniques to Evaluate Drug Release Mechanisms from Hydrophilic Matrix Tablets

C. Melia, H. Williams, Samuel R. Pygall, 2014 .

Microstructural imaging of early gel layer formation in HPMC matrices.

C. Melia, C. Sammon, P. Timmins, 2006, Journal of pharmaceutical sciences.

Investigating in vitro drug release mechanisms inside dosage forms. Monitoring liquid ingress in HPMC hydrophilic matrices using confocal microscopy.

C. Melia, J. Devane, P. Marshall, 1997, Advances in experimental medicine and biology.

Pharmaceutical applications of magnetic resonance imaging (MRI).

Karsten Mäder, Richard W Bowtell, R. Bowtell, 2005, Advanced drug delivery reviews.

Extended release of flurbiprofen from tromethamine-buffered HPMC hydrophilic matrix tablets

C. Melia, P. Timmins, S. Pygall, 2018, Pharmaceutical development and technology.

The influence of polymer content on early gel-layer formation in HPMC matrices: The use of CLSM visualisation to identify the percolation threshold.

Pranav Gupta, Isidoro Caraballo, Jonathan C Burley, 2015, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Hydrophilic matrix sustained release systems based on polysaccharide carriers.

C. Melia, 1991, Critical reviews in therapeutic drug carrier systems.

Structure and Behavior in Hydrophilic Matrix Sustained Release Dosage Forms: 4. Studies of Water Mobility and Diffusion Coefficients in the Gel Layer of HPMC Tablets Using NMR Imaging

Martyn C. Davies, Peter Mansfield, Ali R. Rajabi-Siahboomi, 1996, Pharmaceutical Research.

Investigating the coating-dependent release mechanism of a pulsatile capsule using NMR microscopy.

Walter Köckenberger, Richard W Bowtell, R. Bowtell, 2003, Journal of controlled release : official journal of the Controlled Release Society.

The transit rate of different-sized model dosage forms through the human colon and the effects of a lactulose-induced catharsis

Clive G. Wilson, R. Spiller, M. Davies, 1992 .

Holes in Starch Granules: Confocal, SEM and Light Microscopy Studies of Starch Granule Structure

M. Davies, P. M. Baldwin, C. Melia, 1994 .

Measurement and Mapping of pH in Hydrating Pharmaceutical Pellets Using Confocal Laser Scanning Microscopy

Stephen Hibberd, C. Melia, Colin D. Melia, 2002, Pharmaceutical Research.

Design and Evaluation of an Emulsion Vehicle for Paclitaxel. I. Physicochemical Properties and Plasma Stability

S. Davis, C. Washington, C. Melia, 2004, Pharmaceutical Research.

Radiolabelling of polymer microspheres for scintigraphic investigations by neutron activation. 4. A pharmacoscintigraphic study of colon-targeted Eudragit RS-sulphapyridine microspheres in human volunteers

Clive G. Wilson, M. Davies, C. Melia, 1994 .

Radiolabelling of polymer microspheres for scintigraphic investigations by neutron activation. 3. Changes in the physical properties of Eudragit RS-sulphapyridine microspheres from incorporating samarium oxide

Clive G. Wilson, M. Davies, C. Melia, 1993 .

Radiolabelling of polymer microspheres for scintigraphic investigations by neutron activation. 2. Effects of irradiation on the properties of Eudragit RS-sulphasalazine microspheres

Clive G. Wilson, M. Davies, C. Melia, 1993 .

Quantitative, noninvasive assessment of antidiarrheal actions of codeine using an experimental model of diarrhea in man

R. Spiller, N. Maskell, C. Melia, 1993, Digestive Diseases and Sciences.

Characterisation of the in vivo behaviour of a controlled-release formulation of levodopa (Sinemet CR).

I. Wilding, S. Davis, C. Melia, 1991, Clinical neuropharmacology.

Deposition of a model substance, 99m Tc E-HIDA, in the oral cavity after administration of lozenges, chewing gum and sublingual tablets

I. Wilding, S. Davis, C. Melia, 1990 .

Starch Damage Part 1: Characterisation of Granule Damage in Ball‐milled Potato Starch Study by SEM

M. Davies, P. M. Baldwin, C. Melia, 1995 .

Starch Damage Part 2: Types of Damage in Ball‐milled Potato Starch, upon Hydration Observed by Confocal Microscopy

P. M. Baldwin, C. Melia, J. Adler, 1995 .

Magnetic resonance imaging of controlled release pharmaceutical dosage forms

Richard Bowtell, Ali R. Rajabi-Siahboomi, R. Bowtell, 1998 .

A method for quantifying differential expansion within hydrating hydrophilic matrixes by tracking embedded fluorescent microspheres.

C. Melia, J. Adler, A. Jayan, 1999, Journal of pharmaceutical sciences.

CHANGES IN DRUG DISTRIBUTION AND INTERNAL STRUCTURE OF ORAL PELLET SYSTEMSDURING IN VITRO DISSOLUTION : CRYOGENIC SCANNING ELECTRON MICROSCOPY AND X- RAY MICROANALYSIS

K. A. Khan, I. Wilding, C. Melia, 1992 .

Designing HPMC matrices with improved resistance to dissolved sugar.

C. Melia, H. Williams, R. Ward, 2010, International journal of pharmaceutics.

Determination of localized diffusion coefficients in gels using confocal scanning laser microscopy

C. Melia, M. Davies, J. Adler, 1995 .

The Properties of HPMC:PEO Extended Release Hydrophilic Matrices and their Response to Ionic Environments

L. Gladden, C. Melia, B. Wolf, 2017, Pharmaceutical Research.

Oesophageal bioadhesion of sodium alginate suspensions: particle swelling and mucosal retention.

C. Melia, F. Hampson, P. Dettmar, 2004, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Structure and behaviour in hydrophilic matrix sustained release dosage forms: 2. NMR-imaging studies of dimensional changes in the gel layer and core of HPMC tablets undergoing hydration

Richard Bowtell, Peter Mansfield, M. C. Davies, 1994 .

Structure and behaviour of hydrophilic matrix sustained release dosage forms: 1. The origin and mechanism of formation of gas bubbles in the hydrated surface layer

John R. Mitchell, Ali R. Rajabi-Siahboomi, C. Melia, 1993 .

Gastrointestinal transit of Sinemet CR in healthy volunteers.

I. Wilding, S. Davis, C. Melia, 1989, Neurology.

Determining the molar mass of a plasma substitute succinylated gelatin by size exclusion chromatography-multi-angle laser light scattering, sedimentation equilibrium and conventional size exclusion chromatography.

K. Hardie, C. Melia, A. Hardman, 2002, Journal of chromatography. A.

The applications of near-infrared Fourier transform Raman spectroscopy to the analysis of polymorphic forms of cimetidine

M. C. Davies, Patrick J. Hendra, R. Mitchell, 1991 .

NMR microscopy of hydrating hydrophilic matrix pharmaceutical tablets.

R Bowtell, P Mansfield, M C Davies, 1994, Magnetic resonance imaging.

A simple, high throughput method for the quantification of sodium alginates on oesophageal mucosa.

C. Melia, F. Hampson, P. Dettmar, 2004, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

The application of Fourier transform Raman spectroscopy to the analysis of poly(anhydride) homo- and co-polymers

R. Langer, M. Davies, C. Melia, 1991 .

The application of Fourier-transform Raman spectroscopy to the analysis of pharmaceuticals and biomaterials.

M. Davies, C. Melia, P. Hendra, 1990, Journal of pharmaceutical and biomedical analysis.

An Investigation into the Rheology of Pharmaceutical Inter-granular Material Bridges at High Shear Rates

C. Roberts, C. Melia, Barry Crean, 2009, Pharmaceutical Research.