D. Zhong

发表

Stability of baicalin in biological fluids in vitro.

J. Xing, Xiaoyan Chen, D. Zhong, 2005, Journal of pharmaceutical and biomedical analysis.

Simultaneous determination of capecitabine and its three nucleoside metabolites in human plasma by high performance liquid chromatography-tandem mass spectrometry.

Xiaoyan Chen, D. Zhong, P. Deng, 2015, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

A continued saga of Boc5, the first non-peptidic glucagon-like peptide-1 receptor agonist with in vivo activities

Min He, Wei-wei Gao, Qing Liu, 2012, Acta Pharmacologica Sinica.

Impacts of CYP2C19 genetic polymorphisms on bioavailability and effect on platelet adhesion of vicagrel, a novel thienopyridine P2Y12 inhibitor

D. Zhong, Hongbin Sun, Yifan Zhang, 2020, British journal of clinical pharmacology.

Applications of liquid chromatography-tandem mass spectrometry in drug and biomedical analyses.

Dafang Zhong, Jingkai Gu, Xiaoyan Chen, 2001, Clinica chimica acta; international journal of clinical chemistry.

Pharmacokinetic Drug Interactions of Apatinib With Rifampin and Itraconazole

Xiaoyan Chen, D. Zhong, Yifan Zhang, 2018, Journal of clinical pharmacology.

Effects of Rifampin and Ketoconazole on Pharmacokinetics of Morinidazole in Healthy Chinese Subjects

Xiaoyan Chen, D. Zhong, Yifan Zhang, 2014, Antimicrobial Agents and Chemotherapy.

Preclinical pharmacokinetics of TPN729MA, a novel PDE5 inhibitor, and prediction of its human pharmacokinetics using a PBPK model

Xiaoyan Chen, D. Zhong, Yifan Zhang, 2015, Acta Pharmacologica Sinica.

Identification of Amiodarone Metabolites in Human Bile by Ultraperformance Liquid Chromatography/Quadrupole Time-of-Flight Mass Spectrometry

Xiaoyan Chen, D. Zhong, P. Deng, 2011, Drug Metabolism and Disposition.

Liquid chromatography-mass spectrometry method for the quantification of an anti-sclerostin monoclonal antibody in cynomolgus monkey serum

D. Zhong, Yuxiong Gao, Zhendong Chen, 2020, Journal of pharmaceutical analysis.

Effect of autoinduction and food on the pharmacokinetics of furmonertinib and its active metabolite characterized by a population pharmacokinetic model

Z. Zuo, D. Zhong, Yifan Zhang, 2021, Acta Pharmacologica Sinica.

Validated LC-MS/MS method for quantitative determination of rasagiline in human plasma and its application to a pharmacokinetic study.

Xiaoyan Chen, D. Zhong, P. Deng, 2008, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

pH‐ and NIR Light‐Responsive Micelles with Hyperthermia‐Triggered Tumor Penetration and Cytoplasm Drug Release to Reverse Doxorubicin Resistance in Breast Cancer

Siling Wang, D. Zhong, Yaping Li, 2015 .

Metabolite profiling and identification of triptolide in rats.

Xiaoyan Chen, D. Zhong, Jia Liu, 2013, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Characterization of covalent binding of tyrosine kinase inhibitors to plasma proteins.

M. Zheng, D. Zhong, Yongmei Cui, 2020, Drug metabolism and pharmacokinetics.

Synthesis and Biological Evaluation of 1,3,3,4‐Tetrasubstituted Pyrrolidine CCR5 Receptor Antagonists. Discovery of a Potent and Orally Bioavailable Anti‐HIV Agent

Kunqian Yu, Hualiang Jiang, Renxiao Wang, 2007, ChemMedChem.

Carboxylesterase 2 and Intestine Transporters Contribute to the Low Bioavailability of Allisartan, a Prodrug of Exp3174 for Hypertension Treatment in Humans

Xiaoyan Chen, D. Zhong, Zi-tao Guo, 2019, Drug Metabolism and Disposition.

Pharmacokinetics, Mass Balance, and Metabolism of the Novel Urate Transporter 1 Inhibitor [14C]HR011303 in Humans: Metabolism Is Mediated Predominantly by UDP-Glucuronosyltransferase

D. Zhong, L. Miao, Yan Zhan, 2021, Drug Metabolism and Disposition.

Sulfation predominates the pharmacokinetics, metabolism, and excretion of forsythin in humans: major enzymes and transporters identified

D. Zhong, Min-quan Hui, L. Pan, 2020, Acta pharmacologica Sinica.

A novel metabolic pathway of morphine: formation of morphine glucosides in cancer patients.

D. Zhong, X. Chen, L. M. Zhao, 2003, British journal of clinical pharmacology.

Identification of modification sites on human serum albumin and human hemoglobin adducts with houttuynin using liquid chromatography coupled with mass spectrometry.

Xiaoyan Chen, D. Zhong, Z. Deng, 2012, Biomedical chromatography : BMC.

Validated method for rapid inhibition screening of six cytochrome P450 enzymes by liquid chromatography-tandem mass spectrometry.

Xiaoyan Chen, D. Zhong, Linlin Wang, 2007, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

A bridging immunogenicity assay for monoclonal antibody: case study with SHR-1222.

Xiaoyan Chen, D. Zhong, Changyong Yang, 2018, Bioanalysis.

[Bioanalysis in the development of antibody-drug conjugates].

Xiaoyan Chen, D. Zhong, Xiu-li Li, 2016, Yao xue xue bao = Acta pharmaceutica Sinica.

Pharmacokinetics, Metabolism, and Excretion of the Antiviral Drug Arbidol in Humans

Xiaoyan Chen, D. Zhong, P. Deng, 2013, Antimicrobial Agents and Chemotherapy.

Pharmacokinetic Differences between Pantoprazole Enantiomers in Rats

D. Zhong, Haiyan Xu, Z. Xie, 2005, Pharmaceutical Research.

Derivatization methods for LC-MS analysis of endogenous compounds.

D. Zhong, P. Deng, Yun-ting Zhu, 2015, Bioanalysis.

Fasiglifam (TAK-875) Inhibits Hepatobiliary Transporters: A Possible Factor Contributing to Fasiglifam-Induced Liver Injury

Xiaoyan Chen, D. Zhong, Zi-tao Guo, 2015, Drug Metabolism and Disposition.

Bioanalysis of an oligonucleotide and its metabolites by liquid chromatography-tandem mass spectrometry.

Xiaoyan Chen, D. Zhong, P. Deng, 2010, Journal of pharmaceutical and biomedical analysis.

Crystal structures of two phytohormone signal-transducing α/β hydrolases: karrikin-signaling KAI2 and strigolactone-signaling DWARF14

Yechun Xu, Yonghong Wang, Jiayang Li, 2013, Cell Research.

Application of a sensitive liquid chromatographic/tandem mass spectrometric method to pharmacokinetic study of nalmefene in humans.

Ping Li, A. Wen, Xiaoyan Chen, 2007, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Metabolic disposition of the EGFR covalent inhibitor furmonertinib in humans

D. Zhong, L. Miao, Yifan Zhang, 2021, Acta pharmacologica Sinica.

Phase I study of the safety, pharmacokinetics and antitumor activity of famitinib

Xiaoyan Chen, D. Zhong, Aiping Zhou, 2013, Cancer Chemotherapy and Pharmacology.

Metabolism and Pharmacokinetics of Morinidazole in Humans: Identification of Diastereoisomeric Morpholine N+-Glucuronides Catalyzed by UDP Glucuronosyltransferase 1A9

Xiaoyan Chen, D. Zhong, Cen Xie, 2012, Drug Metabolism and Disposition.

Metabolism and Pharmacokinetics of Morinidazole in Humans : Identification of Diastereoisomeric Morpholine N-Glucuronides Catalyzed by UDP Glucuronosyltransferase 1 A 9

Xiaoyan Chen, D. Zhong, Cen Xie, 2011 .

Simultaneous determination of 6R-leucovorin, 6S-leucovorin and 5-methyltetrahydrofolate in human plasma using solid phase extraction and chiral liquid chromatography-tandem mass spectrometry.

Xiaoyan Chen, D. Zhong, P. Deng, 2009, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Effects of Food on the Pharmacokinetic Properties and Mass Balance of Henagliflozin in Healthy Male Volunteers.

Jian-jun Zou, D. Zhong, Yifan Zhang, 2021, Clinical therapeutics.

Quantitation of the flavonoid wogonin and its major metabolite wogonin-7 beta-D-glucuronide in rat plasma by liquid chromatography-tandem mass spectrometry.

Xiaoyan Chen, D. Zhong, Hongyan Wang, 2002, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Title: Safety, Efficacy and Biomarker Analysis of Pyrotinib in Combination with Capecitabine in HER2-Positive Metastatic Breast Cancer Patients: A Phase I Clinical Trial

Yang Luo, Bing-he Xu, D. Zhong, 2019 .

Screening for in vivo metabolites of isovalertatin family oligosaccharides in rats by liquid chromatography coupled to electrospray ionization tandem mass spectrometry.

D. Zhong, Changxiao Liu, Duan-yun Si, 2006, Rapid communications in mass spectrometry : RCM.

Investigation of microemulsion system for transdermal delivery of meloxicam.

D. Zhong, Yue Yuan, San-ming Li, 2006, International journal of pharmaceutics.

Pulmonary Toxicity and Metabolic Activation of Dauricine in CD-1 Mice

Xiaoyan Chen, D. Zhong, Jia Liu, 2010, Journal of Pharmacology and Experimental Therapeutics.

Nimesulide and 4′-Hydroxynimesulide as Bile Acid Transporters Inhibitors Are Contributory Factors for Drug-Induced Cholestasis

Xiaoyan Chen, D. Zhong, Xiaoyan Pang, 2017, Drug Metabolism and Disposition.

Enantioselective quantification of chiral drugs in human plasma with LC-MS/MS.

Xiaoyan Chen, D. Zhong, Ke-Shun Liu, 2009, Bioanalysis.

Derivatization methods for quantitative bioanalysis by LC-MS/MS.

Xiaoyan Chen, D. Zhong, P. Deng, 2012, Bioanalysis.

Trimethylsilyldiazomethane derivatization coupled with solid-phase extraction for the determination of alendronate in human plasma by LC-MS/MS

Xiaoyan Chen, D. Zhong, Ke-Shun Liu, 2011, Analytical and Bioanalytical Chemistry.

Novel MS detection methods

D. Zhong, P. Deng, 2015 .

Mechanism of Reductive Metabolism and Chiral Inversion of Proton Pump Inhibitors

Weiliang Zhu, Xiaoyan Chen, D. Zhong, 2019, Drug Metabolism and Disposition.

Quantification of polar drugs in human plasma with liquid chromatography-tandem mass spectrometry.

Xiaoyan Chen, D. Zhong, P. Deng, 2009, Bioanalysis.

Structural revision of isovalertatins M03, M13, and M23 isolated from the culture of Streptomyces luteogriseus.

D. Zhong, L. Zhao, D. Si, 2001, Carbohydrate research.

Site-specific protein modification by 3-n-butylphthalide in primary hepatocytes: Covalent protein adducts diminished by glutathione and N-acetylcysteine.

D. Zhong, Yaru Xue, X. Diao, 2021, Life sciences.

Pretreatment with broad-spectrum antibiotics alters the pharmacokinetics of major constituents of Shaoyao-Gancao decoction in rats after oral administration

M. Liu, Sheng Yao, D. Zhong, 2019, Acta Pharmacologica Sinica.

Evaluation of Tolerability, Pharmacokinetics and Pharmacodynamics of Vicagrel, a Novel P2Y12 Antagonist, in Healthy Chinese Volunteers

J. Niu, D. Zhong, Wei Li, 2018, Front. Pharmacol..

Influence of dosage forms on pharmacokinetics of daidzein and its main metabolite daidzein-7-O-glucuronide in rats

Xiaoyan Chen, D. Zhong, Changxiao Liu, 2005, Acta Pharmacologica Sinica.

Identification of the ortho-Benzoquinone Intermediate of 5-O-Caffeoylquinic Acid In Vitro and In Vivo: Comparison of Bioactivation under Normal and Pathological Situations

Xiaoyan Chen, D. Zhong, Cen Xie, 2012, Drug Metabolism and Disposition.

Investigation of isomeric transformations of chlorogenic acid in buffers and biological matrixes by ultraperformance liquid chromatography coupled with hybrid quadrupole/ion mobility/orthogonal acceleration time-of-flight mass spectrometry.

A. Millar, Xiaoyan Chen, D. Zhong, 2011, Journal of agricultural and food chemistry.

Absorption and Disposition of Scutellarin in Rats: A Pharmacokinetic Explanation for the High Exposure of Its Isomeric Metabolite

Xiaoyan Chen, D. Zhong, Chunying Gao, 2011, Drug Metabolism and Disposition.

Formation of 4′-carboxyl acid metabolite of imrecoxib by rat liver microsomes

Ai-shen Gong, Hai-Yan Xu, D. Zhong, 2006, Acta Pharmacologica Sinica.

In vitro identification of metabolites of verapamil in rat liver microsomes.

D. Zhong, Lu Sun, Shu-qiu Zhang, 2004, Acta pharmacologica Sinica.

The metabolism of CYP2C9 and CYP2C19 for gliclazide by homology modeling and docking study.

Yuan Yao, Y. Yao, Zesheng Li, 2009, European journal of medicinal chemistry.

Influence of CYP2C9 and CYP2C19 genetic polymorphisms on pharmacokinetics of gliclazide MR in Chinese subjects.

Xiaoyan Chen, D. Zhong, Yingjie Guo, 2007, British journal of clinical pharmacology.

Simultaneous determination of flumatinib and its two major metabolites in plasma of chronic myelogenous leukemia patients by liquid chromatography-tandem mass spectrometry.

Xiaoyan Chen, D. Zhong, Ke-Shun Liu, 2012, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Quantifying tetrapeptide SS-20 in rat plasma using hydrophilic interaction liquid chromatography coupled with electrospray ionization tandem mass spectrometry.

Xiaoyan Chen, D. Zhong, Yan Zhan, 2011, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Metabolism and Pharmacokinetics of 3-n-Butylphthalide (NBP) in Humans: The Role of Cytochrome P450s and Alcohol Dehydrogenase in Biotransformation

Xiaoyan Chen, D. Zhong, P. Deng, 2013, Drug Metabolism and Disposition.

DMD049684 430..444

Xiaoyan Chen, D. Zhong, P. Deng, 2013 .

Metabolism and Pharmacokinetics of 3n-Butylphthalide ( NBP ) in Humans : The Role of Cytochrome P 450 s and Alcohol Dehydrogenase in Biotransformation s

Xiaoyan Chen, D. Zhong, P. Deng, 2013 .

Characterization of ornidazole metabolites in human bile after intraveneous doses by ultraperformance liquid chromatography/quadrupole time-of-flight mass spectrometry

Xiaoyan Chen, D. Zhong, P. Deng, 2012 .

Tolerability, Pharmacokinetic, and Pharmacodynamic Profiles of Henagliflozin, a Novel Selective Inhibitor of Sodium-Glucose Cotransporter 2, in Healthy Subjects following Single- and Multiple-dose Administration.

Jian-jun Zou, D. Zhong, Yifan Zhang, 2021, Clinical therapeutics.

Development and validation of a liquid chromatography/tandem mass spectrometry procedure for the quantification of adefovir in human plasma.

Xiaoyan Chen, D. Zhong, Lin-Lin Zhu, 2005, Rapid communications in mass spectrometry : RCM.

Differences in the In Vivo and In Vitro Metabolism of Imrecoxib in Humans: Formation of the Rate-Limiting Aldehyde Intermediate

Xiaoyan Chen, D. Zhong, Yifan Zhang, 2018, Drug Metabolism and Disposition.

Determination of scutellarin in rat plasma by high-performance liquid chromatography with ultraviolet detection.

Xiaoyan Chen, D. Zhong, J. Xu, 2003, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Anti‐tussive activity of benproperine enantiomers on citric‐acid‐induced cough in conscious guinea‐pigs

D. Zhong, Yan Li, Weijing Li, 2004, The Journal of pharmacy and pharmacology.

Effect of ethnicity on vinorelbine pharmacokinetics: a population pharmacokinetics analysis

Xiaoyan Chen, D. Zhong, Zhang Li, 2019, Cancer Chemotherapy and Pharmacology.

Determination of carbocysteine in human plasma by liquid chromatography/tandem mass spectrometry employing precolumn derivatization.

Xiaoyan Chen, D. Zhong, Z. Xie, 2003, Rapid communications in mass spectrometry : RCM.

ROLE OF CYP 2 C 9 AND ITS VARIANTS ( CYP 2 C 9 * 3 AND CYP 2 C 9 * 13 ) IN THE METABOLISM OF LORNOXICAM IN HUMANS

Xiaoyan Chen, D. Zhong, Yingjie Guo, 2005 .

Biotransformation of tolbutamide to 4′-hydroxytolbutamide by the fungus Cunninghamella blakesleeana

D. Zhong, Hai-hua Huang, Qiang Li, 2006, Applied Microbiology and Biotechnology.

The inhibition effect of 20(S)-Protopanaxadiol (PPD) and Ginsenoside Rh2 for CYP2C9 and CYP3A4

Y. Yao, Zesheng Li, Xiaoyan Chen, 2007 .

[Clinical pharmacokinetics of small molecule tyrosine kinase inhibitors].

D. Zhong, Juefang Ding, 2013, Yao xue xue bao = Acta pharmaceutica Sinica.

Quantification of Erdosteine in the Low-volume of Dog Plasma by Liquid Chromatography Tandem Mass Spectrometry

Xiaoyan Chen, D. Zhong, Yun-biao Tang, 2007 .

Molecular docking study of the affinity of CYP2C9 and CYP2D6 for imrecoxib

Y. Yao, Zesheng Li, D. Zhong, 2007 .

Metabolic characterization of pyrotinib in humans by ultra-performance liquid chromatography/quadrupole time-of-flight mass spectrometry.

Xiaoyan Chen, D. Zhong, Yun-ting Zhu, 2016, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Arylacetamide Deacetylase Is Involved in Vicagrel Bioactivation in Humans

Xiaoyan Chen, D. Zhong, Jinfang Jiang, 2017, Front. Pharmacol..

Metabolism and pharmacokinetics of vicagrel, a novel thienopyridine P2Y12 inhibitor, compared with clopidogrel in healthy Chinese subjects

Xiaoyan Chen, D. Zhong, Cai Liu, 2017 .

Development of a liquid chromatographic–tandem mass spectrometric method with precolumn derivatization for the determination of dencichine in rat plasma

Yong Zhang, Xiaoyan Chen, D. Zhong, 2006 .

Population Pharmacokinetic and Covariate Analysis of Apatinib, an Oral Tyrosine Kinase Inhibitor, in Healthy Volunteers and Patients with Solid Tumors

Xiaoyan Chen, D. Zhong, Xiao-jian Dai, 2016, Clinical Pharmacokinetics.

Pharmacokinetics and pharmacokinetic/pharmacodynamic relationship of vicagrel, a novel thienopyridine P2Y12 inhibitor, compared with clopidogrel in healthy Chinese subjects following single oral dosing

Xiaoyan Chen, D. Zhong, Wei Li, 2019, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Human Liver Cytochrome P450 Enzymes and Microsomal Thiol Methyltransferase Are Involved in the Stereoselective Formation and Methylation of the Pharmacologically Active Metabolite of Clopidogrel

Weiliang Zhu, Xiaoyan Chen, D. Zhong, 2015, Drug Metabolism and Disposition.

Microsoft Word-4997871-file00

Xiaoyan Chen, D. Zhong, Zhaoqiang Chen, 2015 .

DMD064949 1632..1641

Weiliang Zhu, Xiaoyan Chen, D. Zhong, 2015 .

Development and validation of a sensitive and rapid UHPLC–MS/MS method for the simultaneous quantification of the common active and inactive metabolites of vicagrel and clopidogrel in human plasma

Xiaoyan Chen, D. Zhong, Hongbin Sun, 2018, Journal of pharmaceutical and biomedical analysis.

Absorption, metabolism, and excretion of [14C]YY-20394, a highly selective PI3K-Delta inhibitor in humans

D. Zhong, L. Miao, Yifan Zhang, 2022, Xenobiotica; the fate of foreign compounds in biological systems.

Liquid chromatography/tandem mass spectrometry for pharmacokinetic studies of 20(R)-ginsenoside Rg3 in dog.

Xiaoyan Chen, D. Zhong, J. Xu, 2005, Rapid communications in mass spectrometry : RCM.

Two validated liquid chromatography-mass spectrometry methods with different pretreatments for the quantification of an anti-CD47 monoclonal antibody in rat and cynomolgus monkey serum compared with an electrochemiluminescence method.

D. Zhong, Xiao-tao Duan, Yuxiong Gao, 2019, Journal of pharmaceutical and biomedical analysis.

Effect of N-methyl deuteration on metabolism and pharmacokinetics of enzalutamide

Xiaoyan Chen, D. Zhong, Xiao-jian Dai, 2016, Drug design, development and therapy.

Sensitive liquid chromatography-tandem mass spectrometry method for the determination of cefixime in human plasma: application to a pharmacokinetic study.

Xiaoyan Chen, D. Zhong, Fang Meng, 2005, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

A pH-Responsive Host-guest Nanosystem Loading Succinobucol Suppresses Lung Metastasis of Breast Cancer

D. Zhong, Yaping Li, Pengcheng Zhang, 2016, Theranostics.

Derivatization of (5R)-hydroxytriptolide from benzylamine to enhance mass spectrometric detection: application to a Phase I pharmacokinetic study in humans.

Xiaoyan Chen, D. Zhong, Ke-Shun Liu, 2011, Analytica chimica acta.

Effects of Apatinib on the Pharmacokinetics of Nifedipine and Warfarin in Patients with Advanced Solid Tumors

Yunpeng Liu, X. Qu, Xiaoyan Chen, 2020, Drug design, development and therapy.

Metabolite profiles and mass balance of fuzuloparib, a novel poly (ADP‐ribose) polymerase inhibitor, in subjects with advanced solid cancers

D. Zhong, Linsheng Liu, Chenrong Huang, 2022, British journal of clinical pharmacology.

Development and validation of a sensitive LC-MS/MS assay for the simultaneous quantification of allitinib and its two metabolites in human plasma.

Xiaoyan Chen, D. Zhong, Zhi-wei Gao, 2013, Journal of pharmaceutical and biomedical analysis.

Metabolite identification of a new antitumor agent icotinib in rats using liquid chromatography/tandem mass spectrometry.

Xiaoyan Chen, D. Zhong, Yinxiang Wang, 2008, Rapid communications in mass spectrometry : RCM.

Rapid determination of metformin in human plasma by liquid chromatography-tandem mass spectrometry method.

Xiaoyan Chen, D. Zhong, F. Qiu, 2004, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Safety, Clinical Activity, and Pharmacokinetics of Al ﬂ utinib (AST2818) in Patients With Advanced NSCLC With EGFR T790M Mutation

D. Zhong, N. Yang, S. Qin, 2020 .

Lornoxicam pharmacokinetics in relation to cytochrome P450 2C9 genotype.

Xiaoyan Chen, D. Zhong, Yingjie Guo, 2005, British journal of clinical pharmacology.

Identification of a novel variant CYP2C9 allele in Chinese.

D. Zhong, Yingjie Guo, Yifan Zhang, 2004, Pharmacogenetics.

Stereoselective pharmacokinetics of propafenone and its major metabolites in healthy Chinese volunteers.

D. Zhong, H. Blume, X. Chen, 2000, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Simultaneous determination of alflutinib and its active metabolite in human plasma using liquid chromatography-tandem mass spectrometry.

Xiaoyun Liu, D. Zhong, Wei Li, 2019, Journal of pharmaceutical and biomedical analysis.

Pulmonary toxicity and metabolic activation of tetrandrine in CD-1 mice.

Xiaoyan Chen, D. Zhong, Jia Liu, 2011, Chemical research in toxicology.

Increased Plasma Exposures of Conjugated Metabolites of Morinidazole in Renal Failure Patients: A Critical Role of Uremic Toxins

Xiaoyan Chen, D. Zhong, Zi-tao Guo, 2017, Drug Metabolism and Disposition.

Enantioselective determination of ornidazole in human plasma by liquid chromatography-tandem mass spectrometry on a Chiral-AGP column.

Xiaoyan Chen, D. Zhong, Yifan Zhang, 2013, Journal of pharmaceutical and biomedical analysis.

Development and validation of a sensitive LC-MS/MS method for simultaneous quantification of sinotecan and its active metabolite in human blood.

Xiaoyan Chen, D. Zhong, Yifan Zhang, 2014, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

High-sensitivity liquid chromatography-tandem mass spectrometry method for the simultaneous determination of sodium picosulfate and its three major metabolites in human plasma.

Xiaoyan Chen, D. Zhong, Yu Xia, 2013, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Development and validation of a liquid chromatography-tandem mass spectrometry method for the determination of febuxostat in human plasma.

Xiaoyan Chen, D. Zhong, P. Deng, 2013, Biomedical chromatography : BMC.

Simultaneous determination of apatinib and its four major metabolites in human plasma using liquid chromatography-tandem mass spectrometry and its application to a pharmacokinetic study.

Xiaoyan Chen, D. Zhong, Xiao-jian Dai, 2012, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Quantification of the major metabolites of bromhexine in human plasma using RRLC-MS/MS and its application to pharmacokinetics.

Xiaoyan Chen, D. Zhong, Jia Liu, 2010, Journal of pharmaceutical and biomedical analysis.

Determination of arotinoid acid in human plasma by liquid chromatography-tandem mass spectrometry.

Xiaoyan Chen, D. Zhong, P. Deng, 2009, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Determination of eptifibatide concentration in human plasma utilizing the liquid chromatography-tandem mass spectrometry method.

Xiaoyan Chen, D. Zhong, Xiao-tao Duan, 2009, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

A liquid chromatography/tandem mass spectrometry method for the simultaneous quantification of isoniazid and ethambutol in human plasma.

Xiaoyan Chen, D. Zhong, Kate Yu, 2005, Rapid communications in mass spectrometry : RCM.

Pharmacokinetics of 9-nitro-20(S)-camptothecin in rats.

D. Zhong, Yifan Zhang, Jinghua Xu, 2003, Acta pharmacologica Sinica.

Synthesis and biological evaluation of new N-linked 5-triazolylmethyl oxazolidinones.

D. Zhong, Yushe Yang, Zhiteng Jiang, 2008, European journal of medicinal chemistry.

Microbial transformation of dextromethorphan by Cunninghamella blakesleeana AS 3.153.

D. Zhong, Hai-hua Huang, Peng Zhang, 2007, Chemical & pharmaceutical bulletin.

Biotransformation of indomethacin by the fungus Cunninghamella blakesleeana

Hai-Yan Xu, D. Zhong, Hai-hua Huang, 2006, Acta Pharmacologica Sinica.

Biotransformation of pantoprazole by the fungus Cunninghamella blakesleeana

D. Zhong, Z. Xie, H. Huang, 2005, Xenobiotica; the fate of foreign compounds in biological systems.

Biotransformation of metoprolol by the fungus Cunninghamella blakesleeana

Xiaoyan Chen, D. Zhong, Hai-hua Huang, 2007, Acta Pharmacologica Sinica.

Effects of ketoconazole and rifampicin on the pharmacokinetics of GLS4, a novel anti-hepatitis B virus compound, in dogs

Xiaoyan Chen, D. Zhong, Zhi-wei Gao, 2013, Acta Pharmacologica Sinica.

Isomer-selective distribution of 3-n-butylphthalide (NBP) hydroxylated metabolites, 3-hydroxy-NBP and 10-hydroxy-NBP, across the rat blood-brain barrier

Xiaoyan Chen, D. Zhong, Kan Zhong, 2015, Acta Pharmacologica Sinica.

Bioactivation of 3-n-Butylphthalide via Sulfation of Its Major Metabolite 3-Hydroxy-NBP: Mediated Mainly by Sulfotransferase 1A1

Xiaoyan Chen, D. Zhong, Cen Xie, 2014, Drug Metabolism and Disposition.

Bioactivation of 3n-Butylphthalide via Sulfation of Its Major Metabolite 3-Hydroxy-NBP : Mediated Mainly by Sulfotransferase 1 A 1 s

Xiaoyan Chen, D. Zhong, Cen Xie, 2014 .

Simultaneous quantitation of 3-n-butylphthalide (NBP) and its four major metabolites in human plasma by LC-MS/MS using deuterated internal standards.

Xiaoyan Chen, D. Zhong, Yifan Zhang, 2013, Journal of pharmaceutical and biomedical analysis.

PHARMACOKINETICS AND METABOLISM OF THE FLAVONOID SCUTELLARIN IN HUMANS AFTER A SINGLE ORAL ADMINISTRATION

Xiaoyan Chen, D. Zhong, Xiao-tao Duan, 2006, Drug Metabolism and Disposition.

Determination of zolmitriptan in human plasma by liquid chromatography-tandem mass spectrometry method: application to a pharmacokinetic study.

Xiaoyan Chen, D. Zhong, Y. Luan, 2006, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Enantioselective Total Synthesis of (−)-Strychnine Using the Catalytic Asymmetric Michael Reaction and Tandem Cyclization

D. Zhong, M. Shibasaki, Ryo Takita, 2002 .

Characterization of TPN729 metabolites in humans using ultra-performance liquid chromatography/quadrupole time-of-flight mass spectrometry.

Xiaoyan Chen, D. Zhong, P. Deng, 2016, Journal of pharmaceutical and biomedical analysis.

Simultaneous determination of enalapril and enalaprilat in human plasma by liquid chromatography-tandem mass spectrometry.

Xiaoyan Chen, D. Zhong, Ying-wu Wang, 2004, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Quantification of the major circulating metabolite of BS1801, an ebselen analog, in human plasma.

H. Yin, D. Zhong, Jinfang Jiang, 2022, Journal of pharmaceutical and biomedical analysis.

Rapid and sensitive liquid chromatography-tandem mass spectrometry method for the determination of leuprolide in human serum.

Xiaoyan Chen, D. Zhong, Yan Zhan, 2009, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Bioavailability of clarithromycin cyclodextrin ternary complexes upon oral administration to healthy beagle dogs.

Xiaoyan Chen, D. Zhong, Xiangrong Zhang, 2008, Drug development and industrial pharmacy.

Investigation and Physicochemical Characterization of Clarithromycin–Citric Acid–Cyclodextrins Ternary Complexes

D. Zhong, Xiangrong Zhang, Yifan Zhang, 2007, Drug development and industrial pharmacy.

Evidence for the bioactivation of 4-nonylphenol to quinone methide and ortho-benzoquinone metabolites in human liver microsomes.

F. Nan, Xiaoyan Chen, D. Zhong, 2010, Chemical research in toxicology.

Effects of an Al3+- and Mg2+-containing antacid, ferrous sulfate, and calcium carbonate on the absorption of nemonoxacin (TG-873870) in healthy Chinese volunteers

Yu-Ting Chang, Xiaoyan Chen, D. Zhong, 2014, Acta Pharmacologica Sinica.

[Determination of citalopram in human plasma with LC-MS/MS method and its bioequivalent evaluation].

Xiaoyan Chen, D. Zhong, Yifan Zhang, 2007, Yao xue xue bao = Acta pharmaceutica Sinica.

Determination of meloxicam in human plasma by liquid chromatography-tandem mass spectrometry following transdermal administration.

Xiaoyan Chen, D. Zhong, Yue Yuan, 2007, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Microbial transformation of naproxen by Cunninghamella species.

D. Zhong, Hai-hua Huang, Lu Sun, 2003, Acta pharmacologica Sinica.

Pharmacokinetic studies of meloxicam following oral and transdermal administration in Beagle dogs

Xiaoyan Chen, D. Zhong, Xiu-yan Wei, 2009, Acta Pharmacologica Sinica.

Physicochemical Properties and Evaluation of Microemulsion Systems for Transdermal Delivery of Meloxicam

D. Zhong, Sanming Li, Pan Deng, 2007 .

Simultaneous determination of albendazole and its major active metabolite in human plasma using a sensitive and specific liquid chromatographic-tandem mass spectrometric method.

Xiaoyan Chen, D. Zhong, Haiyan Xu, 2004, Journal of pharmaceutical and biomedical analysis.

Determination of ketotifen and its conjugated metabolite in human plasma by liquid chromatography/tandem mass spectrometry: application to a pharmacokinetic study.

Xiaoyan Chen, D. Zhong, Ying-wu Wang, 2003, Rapid communications in mass spectrometry : RCM.

Enantioselective determination of doxazosin in human plasma by liquid chromatography-tandem mass spectrometry using ovomucoid chiral stationary phase.

Xiaoyan Chen, D. Zhong, Ke-Shun Liu, 2010, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

A fragmentation-based method for the differentiation of glutathione conjugates by high-resolution mass spectrometry with electrospray ionization.

Xiaoyan Chen, D. Zhong, Cen Xie, 2013, Analytica chimica acta.

Development of a dissolution medium for nimodipine tablets based on bioavailability evaluation.

Xiaoyan Chen, D. Zhong, Limei Zhao, 2004, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Determination of ginsenoside compound K in human plasma by liquid chromatography–tandem mass spectrometry of lithium adducts

Xiaoyan Chen, D. Zhong, Liang Zhu, 2015, Acta pharmaceutica Sinica. B.

Determination of vertilmicin in rat serum by high-performance liquid chromatography using 1-fluoro-2,4-dinitrobenzene derivatization.

D. Zhong, Changxiao Liu, Yuming Sun, 2003, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Pharmacokinetics of clarithromycin citrate salt after oral administration to beagle dogs and food effects on its absorption.

D. Zhong, Xiangrong Zhang, Yifan Zhang, 2008, PDA journal of pharmaceutical science and technology.

Chemical and Enzymatic Transformations of Nimesulide to GSH Conjugates through Reductive and Oxidative Mechanisms.

Xiaoyan Chen, D. Zhong, Cen Xie, 2015, Chemical research in toxicology.

Determination of cefaclor in human plasma by a sensitive and specific liquid chromatographic-tandem mass spectrometric method.

Xiaoyan Chen, D. Zhong, Bin Huang, 2003, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Identification of 20(S)-Protopanaxadiol Metabolites in Human Liver Microsomes and Human Hepatocytes

Xiaoyan Chen, D. Zhong, Liang Li, 2011, Drug Metabolism and Disposition.

Validation of a chiral liquid chromatography-tandem mass spectrometry method for the determination of pantoprazole in dog plasma.

Xiaoyan Chen, D. Zhong, Yu Xia, 2012, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Aldehyde Oxidase Mediated Metabolism in Drug-like Molecules: A Combined Computational and Experimental Study.

Liang Li, Pan Deng, Mingyue Zheng, 2017, Journal of medicinal chemistry.

Sensitive and specific liquid chromatographic-tandem mass spectrometric assay for dihydroergotamine and its major metabolite in human plasma.

Xiaoyan Chen, D. Zhong, B. Schug, 2002, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

On-cartridge derivatization coupled with solid-phase extraction for the ultra-sensitive determination of minodronic acid in human plasma by LC-MS/MS method.

Xiaoyan Chen, D. Zhong, Yifan Zhang, 2015, Journal of pharmaceutical and biomedical analysis.

Simultaneous determination of trans-resveratrol-3-O-glucoside and its two metabolites in rat plasma using liquid chromatography with ultraviolet detection.

Xiaoyan Chen, D. Zhong, Mao-jin Zhou, 2007, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Sensitive liquid chromatography-tandem mass spectrometry method for the simultaneous determination of paracetamol and guaifenesin in human plasma.

Xiaoyan Chen, D. Zhong, Jia Huang, 2005, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Characterization of the pharmacokinetics of dioscin in rat

D. Zhong, J. P. Fawcett, J. Gu, 2005, Steroids.

Simultaneous determination of dronedarone and its active metabolite debutyldronedarone in human plasma by liquid chromatography-tandem mass spectrometry: application to a pharmacokinetic study.

Xiaoyan Chen, D. Zhong, Xiao-jian Dai, 2011, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Liquid chromatography/negative ion electrospray tandem mass spectrometry method for the quantification of rosuvastatin in human plasma: application to a pharmacokinetic study.

Xiaoyan Chen, D. Zhong, Xiao-tao Duan, 2007, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

[Simultaneous determination of ephedrine and chlorpheniramine in human plasma by a highly sensitive liquid chromatography-tandem mass spectrometric method].

Xiaoyan Chen, D. Zhong, Xiao-tao Duan, 2006, Yao xue xue bao = Acta pharmaceutica Sinica.

[Determination of lornoxicam in human plasma by LC/MS/MS].

Xiaoyan Chen, D. Zhong, Yifan Zhang, 2004, Yao xue xue bao = Acta pharmaceutica Sinica.

Enantioselective HPLC determination and pharmacokinetic study of secnidazole enantiomers in rats.

Xiaoyan Chen, D. Zhong, Yifan Zhang, 2014, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Stereoselective Glucuronidation of Ornidazole in Humans: Predominant Contribution of UDP-Glucuronosyltransferases 1A9 and 2B7

Xiaoyan Chen, D. Zhong, Tiangeng You, 2013, Drug Metabolism and Disposition.

Interaction of baicalin and baicalein with antibiotics in the gastrointestinal tract

J. Xing, Xiaoyan Chen, D. Zhong, 2005, The Journal of pharmacy and pharmacology.

Study of the electrospray ionization tandem mass spectrometry of sildenafil derivatives.

J. Xing, D. Zhong, Lu Sun, 2002, Rapid communications in mass spectrometry : RCM.

Metabolism of MRX-I, a Novel Antibacterial Oxazolidinone, in Humans: The Oxidative Ring Opening of 2,3-Dihydropyridin-4-One Catalyzed by Non-P450 Enzymes

Zhengyu Yuan, Dafang Zhong, Chen Li, 2015, Drug Metabolism and Disposition.

Microsoft Word-86754198-file00.docx

Jialan, Xiaoyan Chen, D. Zhong, 2015 .

Chronic Morphine Treatment Impaired Hippocampal Long-Term Potentiation and Spatial Memory via Accumulation of Extracellular Adenosine Acting on Adenosine A1 Receptors

Xiaoyan Chen, D. Zhong, Qi-Xin Zhou, 2010, The Journal of Neuroscience.

[Determination of adefovir in monkey plasma by liquid chromatography-tandem mass spectrometry].

Xiaoyan Chen, D. Zhong, Yong Zhang, 2003, Yao xue xue bao = Acta pharmaceutica Sinica.

Small-Molecule Targeting of Oncogenic FTO Demethylase in Acute Myeloid Leukemia.

Hualiang Jiang, Yue Huang, Cai-Guang Yang, 2019, Cancer cell.

Metabolism and Pharmacokinetics of Novel Selective Vascular Endothelial Growth Factor Receptor-2 Inhibitor Apatinib in Humans

Xiaoyan Chen, D. Zhong, Xiao-jian Dai, 2013, Drug Metabolism and Disposition.

Determination of tegafur, 5-fluorouracil, gimeracil and oxonic acid in human plasma using liquid chromatography-tandem mass spectrometry.

Ke Liu, Dafang Zhong, Xiaoyan Chen, 2010, Journal of pharmaceutical and biomedical analysis.

Potential role of organic anion transporting polypeptide 1B1 (OATP1B1) in the selective hepatic uptake of hematoporphyrin monomethyl ether isomers

Xiaoyan Chen, D. Zhong, Zi-tao Guo, 2014, Acta Pharmacologica Sinica.

Safety, Efficacy, and Biomarker Analysis of Pyrotinib in Combination with Capecitabine in HER2-Positive Metastatic Breast Cancer Patients: A Phase I Clinical Trial

Peng Yuan, Jiayu Wang, Qiao Li, 2019, Clinical Cancer Research.

Covalent Binding Mechanism of Furmonertinib and Osimertinib With Human Serum Albumin

D. Zhong, Hao Xue, Qingfeng He, 2022, Drug Metabolism and Disposition.

Small-Molecule Targeting of E3 Ligase Adaptor SPOP in Kidney Cancer.

Cheng Luo, Jin Ren, Ke Chen, 2016, Cancer cell.

Determination of tropisetron in human plasma by liquid chromatography-tandem mass spectrometry.

Xiaoyan Chen, D. Zhong, P. Deng, 2009 .

Metabolism of Flumatinib, a Novel Antineoplastic Tyrosine Kinase Inhibitor, in Chronic Myelogenous Leukemia Patients

Xiaoyan Chen, D. Zhong, P. Deng, 2010, Drug Metabolism and Disposition.

Alflutinib (AST2818), primarily metabolized by CYP3A4, is a potent CYP3A4 inducer

D. Zhong, Yifan Zhang, Xiao-yun Liu, 2020, Acta Pharmacologica Sinica.

A sensitive LC-MS/MS method for the determination of triptolide and its application to pharmacokinetic research in rats.

Xiaoyan Chen, D. Zhong, Ye-chun Xu, 2019, Biomedical chromatography : BMC.

Mechanistic Studies on the Absorption and Disposition of Scutellarin in Humans: Selective OATP2B1-Mediated Hepatic Uptake Is a Likely Key Determinant for Its Unique Pharmacokinetic Characteristics

Xiaoyan Chen, D. Zhong, Chunying Gao, 2012, Drug Metabolism and Disposition.

Simultaneous determination of chlorpheniramine and pseudoephedrine in human plasma by liquid chromatography-tandem mass spectrometry.

Xiaoyan Chen, D. Zhong, Yong Zhang, 2004, Biomedical chromatography : BMC.

Direct quantification of anorethidrani disuccinate and determination of sterol metabolites by chemical derivatization combined with LC-MS/MS: Application to a Phase I pharmacokinetic study in humans.

Xiaoyan Chen, D. Zhong, Liang Li, 2020, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Quantification of rabeprazole in human plasma by liquid chromatography–tandem mass spectrometry

Xiaoyan Chen, D. Zhong, Yong Zhang, 2004 .

Predominant contributions of carboxylesterase 1 and 2 in hydrolysis of anordrin in humans

Xiaoyan Chen, D. Zhong, Jinfang Jiang, 2018, Xenobiotica; the fate of foreign compounds in biological systems.

Development of a UHPLC-MS/MS method for the determination of plasma histamine in various mammalian species.

Xiaoyan Chen, D. Zhong, Jia Liu, 2014, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

A phase I study of AST1306, a novel irreversible EGFR and HER2 kinase inhibitor, in patients with advanced solid tumors

D. Zhong, Si Sun, N. Zhao, 2014, Journal of Hematology & Oncology.

Safety, Clinical Activity and Pharmacokinetics of Alflutinib (AST2818) in Advanced NSCLC Patients with EGFR T790M Mutation.

Jian Feng, D. Zhong, Yuankai Shi, 2020, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

Characterization of metabolites of GLS4 in humans using ultrahigh-performance liquid chromatography/quadrupole time-of-flight mass spectrometry.

Xiaoyan Chen, D. Zhong, P. Deng, 2013, Rapid communications in mass spectrometry : RCM.

Metabolite identification of arbidol in human urine by the study of CID fragmentation pathways using HPLC coupled with ion trap mass spectrometry

Xiaoyan Chen, D. Zhong, Qiang Li, 2008, Journal of mass spectrometry : JMS.

Metabolism and bioactivation of famitinib, a novel inhibitor of receptor tyrosine kinase, in cancer patients

Xiaoyan Chen, D. Zhong, Cen Xie, 2013, British journal of pharmacology.

In Vitro Studies on the Oxidative Metabolism of 20(S)-Ginsenoside Rh2 in Human, Monkey, Dog, Rat, and Mouse Liver Microsomes, and Human Liver S9

Xiaoyan Chen, D. Zhong, Liang Li, 2012, Drug Metabolism and Disposition.

Recent advances in metabolite identification and quantitative bioanalysis by LC-Q-TOF MS.

Dafang Zhong, Xiaoyan Chen, D. Zhong, 2012, Bioanalysis.

Species differences in the CYP3A-catalyzed metabolism of TPN729, a novel PDE5 inhibitor

Zhen Wang, D. Zhong, Jingshan Shen, 2020, Acta Pharmacologica Sinica.

Absorption, distribution, metabolism, and excretion of [14C]TPN729 after oral administration to rats

D. Zhong, X. Diao, Ji-xiang He, 2022, Xenobiotica; the fate of foreign compounds in biological systems.

Stability of glufosfamide in phosphate buffers and in biological samples.

Xiaoyan Chen, D. Zhong, Yuming Sun, 2006, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

9-Glutathionyl-6,7-dihydro-1-hydroxymethyl-5H-pyrrolizine Is the Major Pyrrolic Glutathione Conjugate of Retronecine-Type Pyrrolizidine Alkaloids in Liver Microsomes and in Rats.

Xiaoyan Chen, D. Zhong, Jiang Zheng, 2016, Chemical Research in Toxicology.

Identification of amino acid and glutathione N-conjugates of toosendanin: bioactivation of the furan ring mediated by CYP3A4.

Xiaoyan Chen, D. Zhong, P. Deng, 2014, Chemical research in toxicology.

CYP3A-mediated apoptosis of dauricine in cultured human bronchial epithelial cells and in lungs of CD-1 mice.

Xiaoyan Chen, D. Zhong, Jiang Zheng, 2012, Toxicology and applied pharmacology.

Pharmacokinetics of loratadine and its active metabolite descarboethoxyloratadine in healthy Chinese subjects.

Xiaoyan Chen, D. Zhong, Yifan Zhang, 2003, Acta pharmacologica Sinica.

Identification of the metabolites of roxithromycin in humans.

D. Zhong, A. Wang, Y. Xu, 2000, Drug metabolism and disposition: the biological fate of chemicals.

Bioequivalence of generic alendronate sodium tablets (70 mg) to Fosamax® tablets (70 mg) in fasting, healthy volunteers: a randomized, open-label, three-way, reference-replicated crossover study

Xiaoyan Chen, D. Zhong, Yifan Zhang, 2017, Drug design, development and therapy.

Analysis of O-glucuronide conjugates in urine by electrospray ion trap mass spectrometry

Xiaoyan Chen, D. Zhong, J. Gu, 1999 .

[Characterization of some glucuronide conjugates by electrospray ion trap mass spectrometry].

D. Zhong, X. Chen, J. Gu, 1998, Yao xue xue bao = Acta pharmaceutica Sinica.

Identification of quinone methide metabolites of dauricine in human liver microsomes and in rat bile.

Xiaoyan Chen, D. Zhong, Jiang Zheng, 2009, Chemical research in toxicology.

Development and validation of a sensitive LC-MS/MS assay for simultaneous quantitation of ranolazine and its three metabolites in human plasma.

Y. Wang, Ying Zhang, Xiaoyan Chen, 2012, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Formation of glucoside conjugate of acetaminophen by fungi separated from soil

D. Zhong, L. H. Lin, X. Qi, 2006, European Journal of Drug Metabolism and Pharmacokinetics.

Mechanistic Study on the Species Differences in Excretion Pathway of HR011303 in Humans and Rats

Xiaoyan Chen, D. Zhong, Yaru Xue, 2021, Drug Metabolism and Disposition.

Technologies to improve the sensitivity of existing chromatographic methods used for bioanalytical studies.

D. Zhong, Yuxiong Gao, Zhendong Chen, 2020, Biomedical chromatography : BMC.

Covalent protein binding and tissue distribution of houttuynin in rats after intravenous administration of sodium houttuyfonate

Xiaoyan Chen, D. Zhong, Z. Deng, 2012, Acta Pharmacologica Sinica.

Metabolism of pantoprazole involving conjugation with glutathione in rats

Xiaoyan Chen, D. Zhong, Z. Xie, 2005, The Journal of pharmacy and pharmacology.

Absorption and enterohepatic circulation of baicalin in rats.

J. Xing, Xiaoyan Chen, D. Zhong, 2005, Life sciences.

Precolumn derivatization of cysteine residues for quantitative analysis of five major cytochrome P450 isoenzymes by liquid chromatography/tandem mass spectrometry.

Xiaoyan Chen, D. Zhong, Xiao-tao Duan, 2007, Rapid communications in mass spectrometry : RCM.

Identification of the metabolites of 9-nitro-20(S)-camptothecin in rats.

Xiaoyan Chen, D. Zhong, Yan Li, 2003, Drug metabolism and disposition: the biological fate of chemicals.

A validated HPLC-MS/MS method for determination of simmitecan and its metabolite chimmitecan in human plasma and its application to a pharmacokinetic study in Chinese patients with advanced solid tumor.

L. Shen, Xiaoyan Chen, D. Zhong, 2021, Journal of separation science.

Catalytic activities of human cytochrome P450 2C9*1, 2C9*3 and 2C9*13

H. Zhou, D. Zhong, Y. Wang, 2005, Xenobiotica; the fate of foreign compounds in biological systems.

Bioequivalence of paclitaxel protein-bound particles in patients with breast cancer: determining total and unbound paclitaxel in plasma by rapid equilibrium dialysis and liquid chromatography–tandem mass spectrometry

Xiaoyan Chen, D. Zhong, Xiao-jian Dai, 2019, Drug design, development and therapy.

Effects of Renal Impairment on the Pharmacokinetics of Morinidazole: Uptake Transporter-Mediated Renal Clearance of the Conjugated Metabolites

Xiaoyan Chen, D. Zhong, Cen Xie, 2014, Antimicrobial Agents and Chemotherapy.

Pharmacokinetics of tacrolimus converted from twice-daily formulation to once-daily formulation in Chinese stable liver transplant recipients

Xiaoyan Chen, D. Zhong, Xiao-jian Dai, 2011, Acta Pharmacologica Sinica.

Simultaneous determination of forsythin and its major metabolites in human plasma via liquid chromatography-tandem mass spectrometry.

D. Zhong, Tao Chen, Min-quan Hui, 2021, Journal of pharmaceutical and biomedical analysis.

Structural identification of bitespiramycin metabolites in rat: A single oral dose study

D. Zhong, J. P. Fawcett, X. Shi, 2005, Xenobiotica; the fate of foreign compounds in biological systems.

Acid catalysed degradation of some spiramycin derivatives found in the antibiotic bitespiramycin.

D. Zhong, J. P. Fawcett, Shu-qiu Zhang, 2004, Journal of pharmaceutical and biomedical analysis.

Clopidogrel as a donor probe and thioenol derivatives as flexible promoieties for enabling H2S biomedicine

B. Geng, D. Zhong, Elkin Romero, 2018, Nature Communications.

[Research advances in non-P450-mediated drug oxidative metabolism].

Xiaoyan Chen, D. Zhong, Lei Zhou, 2017, Yao xue xue bao = Acta pharmaceutica Sinica.

Comparative bioavailability and tolerability of a single 20-mg dose of two fluoxetine hydrochloride dispersible tablet formulations in fasting, healthy Chinese male volunteers: an open-label, randomized-sequence, two-period crossover study.

S. Shi, Yani Liu, D. Zhong, 2010, Clinical therapeutics.

Enantioselective determination of 3-n-butylphthalide (NBP) in human plasma by liquid chromatography on a teicoplanin-based chiral column coupled with tandem mass spectrometry.

Xiaoyan Chen, D. Zhong, Yifan Zhang, 2013, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Determination of methacycline in human plasma by liquid chromatography coupled to tandem mass spectrometry

Xiaoyan Chen, D. Zhong, Yifan Zhang, 2005 .

Assignments of 1H and 13C NMR spectral data for ondansetron and its two novel metabolites, 1‐hydroxy‐ondansetron diastereoisomers

Xiaoyan Chen, D. Zhong, Hai-hua Huang, 2006, Magnetic resonance in chemistry : MRC.

CYP3A4 inducer and inhibitor strongly affect the pharmacokinetics of triptolide and its derivative in rats

Xiaoyan Chen, D. Zhong, Yifan Zhang, 2017, Acta Pharmacologica Sinica.

Discovery and development of pyrotinib: A novel irreversible EGFR/HER2 dual tyrosine kinase inhibitor with favorable safety profiles for the treatment of breast cancer

Xin Li, L. Lou, Weikang Tao, 2017, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Discovery and development of pyrotinib : A novel irreversible EGFR / HER 2 dual tyrosine kinase inhibitor with favorable safety pro fi les for the treatment of breast cancer

L. Lou, Weikang Tao, Xiaoyan Chen, 2017 .

Determination of dioscin in rat plasma by liquid chromatography-tandem mass spectrometry.

Xiaoyan Chen, D. Zhong, J. Gu, 2005, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Identification of some benproperine metabolites in humans and investigation of their antitussive effect

D. Zhong, Yan Li, I. Maeba, 2005, Acta Pharmacologica Sinica.

Characterization of in-vivo human metabolites of the oral nucleoside anti-COVID-19 drug VV116 using UHPLC-Orbitrap-MS

D. Zhong, A. Zhou, Zhen Wang, 2023, Journal of Pharmaceutical and Biomedical Analysis.

Derivatization of beta-dicarbonyl compound with 2,4-dinitrophenylhydrazine to enhance mass spectrometric detection: application in quantitative analysis of houttuynin in human plasma.

Xiaoyan Chen, D. Zhong, Xiao-tao Duan, 2008, Journal of mass spectrometry : JMS.

Metabolism and Pharmacokinetics of Allitinib in Cancer Patients: The Roles of Cytochrome P450s and Epoxide Hydrolase in its Biotransformation

Xiaoyan Chen, D. Zhong, Cen Xie, 2014, Drug Metabolism and Disposition.

DMD056341 872..884

Xiaoyan Chen, D. Zhong, Cen Xie, 2014 .

Metabolism and Pharmacokinetics of Allitinib in Cancer Patients: The Roles of Cytochrome P450s and Epoxide Hydrolase in its Biotransformation s

Xiaoyan Chen, D. Zhong, Cen Xie, 2014 .

[Determination of ambroxol and clenbuterol in human plasma by LC-MS/MS method].

Xiaoyan Chen, D. Zhong, N. Lin, 2007, Yao xue xue bao = Acta pharmaceutica Sinica.

High-throughput salting-out-assisted liquid-liquid extraction for the simultaneous determination of atorvastatin, ortho-hydroxyatorvastatin, and para-hydroxyatorvastatin in human plasma using ultrafast liquid chromatography with tandem mass spectrometry.

Xiaoyan Chen, D. Zhong, Yong Yang, 2015, Journal of separation science.

Pharmacokinetics of Telmisartan in Healthy Chinese Subjects after Oral Administration of Two Dosage Levels

Xiaoyan Chen, D. Zhong, Yifan Zhang, 2006, Arzneimittelforschung.

Separation and identification of Aconitum alkaloids and their metabolites in human urine.

Ying Sun, D. Zhong, Han Zhang, 2005, Toxicon : official journal of the International Society on Toxinology.

Quantitative determination of ondansetron in human plasma by enantioselective liquid chromatography-tandem mass spectrometry.

Xiaoyan Chen, D. Zhong, Xiao-jian Dai, 2008, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Impact of curcumin on the pharmacokinetics of rosuvastatin in rats and dogs based on the conjugated metabolites

D. Zhong, Hongliang Jiang, Zi-tao Guo, 2017, Xenobiotica; the fate of foreign compounds in biological systems.

Enantioselective determination of propafenone and its metabolites in human plasma by liquid chromatography-mass spectrometry.

D. Zhong, X. Chen, 1999, Journal of Chromatography B: Biomedical Sciences and Applications.

Advantages of a steady-state crossover design in assessment of bioequivalence of highly variable drugs : propafenone

D. Zhong, B. Schug, B. Scheidel, 1994 .

Determination of zolmitriptan in human plasma by liquid chromatography–tandem mass spectrometry method: Application to a pharmacokinetic study

Xiaoyan Chen, D. Zhong, Y. Luan, 2006 .

Determination of nimodipine in human plasma by a sensitive and selective liquid chromatography-tandem mass spectrometry method.

Xiaoyan Chen, D. Zhong, F. Qiu, 2004, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Pharmacokinetics and Disposition of Contezolid in Humans: Resolution of a Disproportionate Human Metabolite for Clinical Development

Xingdang Liu, D. Zhong, Jing Zhang, 2021, Antimicrobial agents and chemotherapy.

Transformation of Verapamil by Cunninghamella blakesleeana

D. Zhong, Hai-hua Huang, Lu Sun, 2004, Applied and Environmental Microbiology.

ROLE OF CYP2C9 AND ITS VARIANTS (CYP2C9*3 AND CYP2C9*13) IN THE METABOLISM OF LORNOXICAM IN HUMANS

Yifan Zhang, Dafang Zhong, Xiaoyan Chen, 2005, Drug Metabolism and Disposition.

Distribution of CYP2C9*13 allele in the Chinese Han and the long-range haplotype containing CYP2C9*13 and CYP2C19*2.

D. Zhong, Yifan Zhang, Juan Wang, 2012, Biopharmaceutics & drug disposition.

Metabolism and Pharmacokinetics of Novel Selective Vascular Endothelial Growth Factor Receptor-2 Inhibitor Apatinib in Humans s

Xiaoyan Chen, D. Zhong, Xiao-jian Dai, 2013 .

Liquid chromatography/tandem mass spectrometry method for the quantification of deserpidine in human plasma: Application to a pharmacokinetic study.

Xiaoyan Chen, D. Zhong, Xiao-jian Dai, 2009, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Characterization and quantitative determination of henagliflozin metabolites in humans.

D. Zhong, Yifan Zhang, Yan Zhan, 2020, Journal of pharmaceutical and biomedical analysis.

Synthesis of [3- 3 H]20( S )-protopanaxadiol

Xiaoyan Chen, D. Zhong, Lizhi Zhao, 2009 .

Derivatization in Sample Preparation for LC‐MS Bioanalysis

D. Zhong, Yun-ting Zhu, 2019, Sample Preparation in LC‐MS Bioanalysis.

LC-MS-MS analysis of 2-pyridylacetic acid, a major metabolite of betahistine: application to a pharmacokinetic study in healthy volunteers

D. Zhong, X. Chen, B. Yan, 2003, Xenobiotica; the fate of foreign compounds in biological systems.

Bioequivalence of Oral Formulations of Anastrozole in Healthy Chinese Male Volunteers: A Randomized, Single‐Dose, Two‐Period, Two‐Sequence Crossover Study

Xiaoyan Chen, D. Zhong, Jialang Zhuang, 2019, Clinical pharmacology in drug development.

[LC-MS/MS determination of budesonide in dog plasma].

Xiaoyan Chen, D. Zhong, P. Deng, 2008, Yao xue xue bao = Acta pharmaceutica Sinica.

QUANTIFICATION OF LETROZOLE IN HUMAN PLASMA USING LC-(–)ESI-MS/MS WITH D4-LETROZOLE AS INTERNAL STANDARD: APPLICATION IN A PHARMACOKINETIC STUDY

Xiaoyan Chen, D. Zhong, Yifan Zhang, 2012 .

Simultaneous determination of pantoprazole and its two metabolites in dog plasma by HPLC.

Xiaoyan Chen, D. Zhong, Z. Xie, 2005, Journal of chromatographic science.

A mass balance study of [14C]SHR6390 (dalpiciclib), a selective and potent CDK4/6 inhibitor in humans

D. Zhong, Yi-cong Bian, Yan Zhan, 2023, Frontiers in Pharmacology.

Evaluation ofin-vitro dissolution andin-vivo absorption for two different film-coated pellets of clarithromycin

Xiaoyan Chen, D. Zhong, Xiangrong Zhang, 2005, Archives of pharmacal research.

Identification of novel ondansetron metabolites using LC/MSn and NMR.

D. Zhong, Li Qin, Peng Zhang, 2018, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

The effect of Madopar on the pharmacokinetics of ropinirole in healthy Chinese volunteers.

A. Wen, Xiaoyan Chen, D. Zhong, 2007, Journal of pharmaceutical and biomedical analysis.

pH-dependent geometric isomerization of roxithromycin in simulated gastrointestinal fluids and in rats.

J. Xing, D. Zhong, Shu-qiu Zhang, 2004, Journal of pharmaceutical sciences.

Determination of glufosfamide in rat plasma by liquid chromatography/tandem mass spectrometry.

Xiaoyan Chen, D. Zhong, Yuming Sun, 2005, Rapid communications in mass spectrometry : RCM.

[Enantioselective determinination of R-warfarin/S-warfarin in human plasma using liquid chromatography-tandem mass spectrometry and its application in a drug-drug interaction study].

Xiaoyan Chen, D. Zhong, Ke-Shun Liu, 2012, Yao xue xue bao = Acta pharmaceutica Sinica.

Pharmacokinetics, mass balance, and metabolism of [14C]vicagrel, a novel irreversible P2Y12 inhibitor in humans

D. Zhong, Yi-cong Bian, L. Miao, 2020, Acta Pharmacologica Sinica.

Pharmacokinetics, mass balance, and metabolism of [14C]vicagrel, a novel irreversible P2Y12 inhibitor in humans

D. Zhong, Yi-cong Bian, Yan Zhan, 2020, Acta Pharmacologica Sinica.

Metabolism and disposition of pyrotinib in healthy male volunteers: covalent binding with human plasma protein

Xiaoyan Chen, D. Zhong, L. Miao, 2018, Acta Pharmacologica Sinica.

[Simultaneous determination of metformin and glipizide in human plasma by liquid chromatography-tandem mass spectrometry].

Xiaoyan Chen, D. Zhong, B. Song, 2007, Yao xue xue bao = Acta pharmaceutica Sinica.

Rapid and selective liquid chromatographic/tandem mass spectrometric method for the determination of fosfomycin in human plasma.

Xiaoyan Chen, D. Zhong, Hui Chen, 2007, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Analysis of diacylglycerols by ultra performance liquid chromatography-quadrupole time-of-flight mass spectrometry: Double bond location and isomers separation.

Pan Deng, Dafang Zhong, Ying Leng, 2016, Analytica chimica acta.

Effect of Fluconazole on the Pharmacokinetic Properties of Imrecoxib, a Novel NSAID: A Single-center, Open-label, Self-controlled Study in Healthy Chinese Male Volunteers.

D. Zhong, Xiao-yan Chen, R. Zhu, 2018, Clinical therapeutics.

Improved and simplified liquid chromatography/electrospray ionization mass spectrometry method for the analysis of underivatized glucosamine in human plasma.

Xiaoyan Chen, D. Zhong, Sheng Zhong, 2007, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Simultaneous determination of amodiaquine and its active metabolite in human blood by ion-pair liquid chromatography-tandem mass spectrometry.

Xiaoyan Chen, D. Zhong, P. Deng, 2007, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

[Impact of cytochrome P450 CYP2C9 variant allele CYP2C9 * 3 on the pharmacokinetics of glibenclamide and lornoxicam in Chinese subjects].

Xiaoyan Chen, D. Zhong, Yingjie Guo, 2005, Yao xue xue bao = Acta pharmaceutica Sinica.

The effects of CYP2C9 and CYP2C19 genetic polymorphisms on the pharmacokinetics and pharmacodynamics of glipizide in Chinese subjects

Xiaoyan Chen, D. Zhong, Yifan Zhang, 2010, European Journal of Clinical Pharmacology.

Identification and quantitative determination of benproperine metabolites in human plasma and urine by liquid chromatography-tandem mass spectrometry.

D. Zhong, Yifan Zhang, Yuming Sun, 2006, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Simultaneous determination of ornidazole and its main metabolites in human plasma by LC-MS/MS: application to a pharmacokinetic study.

Xiaoyan Chen, D. Zhong, Yifan Zhang, 2014, Bioanalysis.

LC-MS-MS analysis of 2-pyridylacetic acid, a major metabolite of betahistine: application to a pharmacokinetic study in healthy volunteers

D. Zhong, X. Chen, B. Yan, 2003 .

Microsoft Word-46596367-file00

Xiaoyan Chen, D. Zhong, Liang Li, 2010 .

[Metabolites of injected chlorogenic acid in rats].

Xiaoyan Chen, D. Zhong, Cen Xie, 2011, Yao xue xue bao = Acta pharmaceutica Sinica.

Characterization of TPN171 metabolism in humans via ultra-performance liquid chromatography/quadrupole time-of-flight mass spectrometry.

Xiaoyan Chen, D. Zhong, Xiangrui Jiang, 2019, Journal of pharmaceutical and biomedical analysis.

Pharmacokinetics of R-(-)ondansetron compared with that of S-(-)ondansetron in rats using an LC-MS/MS method.

D. Zhong, Yue Yuan, Qi Zhao, 2019, Biomedical chromatography : BMC.

[Pharmacokinetics of meloxicam in healthy Chinese volunteers].

D. Zhong, L. M. Zhao, H. Y. Xu, 2001, Yao xue xue bao = Acta pharmaceutica Sinica.

Determination of three major components of bitespiramycin and their major active metabolites in rat plasma by liquid chromatography-ion trap mass spectrometry.

Xiaoyan Chen, D. Zhong, Lu Sun, 2003, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Tissue distribution of bitespiramycin and spiramycin in rats.

D. Zhong, Yu-feng Zhang, Yu-ming Sun, 2004, Acta pharmacologica Sinica.

Microsoft Word-77887028-file00

Xiaoyan Chen, D. Zhong, P. Deng, 2010 .

Inhibitor, in Chronic Myelogenous Leukemia Patients

Xiaoyan Chen, D. Zhong, P. Deng, 2010 .

Phase II metabolites of etofesalamide in filamentous fungi

Qiang Li, D. Zhong, Hai-hua Huang, 2005, Acta Pharmacologica Sinica.

Hydrolytic Metabolism of Cyanopyrrolidine DPP-4 Inhibitors Mediated by Dipeptidyl Peptidases

M. Zheng, Jihui Zhao, Xiaoyan Chen, 2018, Drug Metabolism and Disposition.

Characterization of metabolites of a novel histamine H(2)-receptor antagonist, lafutidine, in human liver microsomes by liquid chromatography coupled with ion trap mass spectrometry.

Xiaoyan Chen, D. Zhong, Qiang Li, 2008, Rapid communications in mass spectrometry : RCM.

Study on the bioavailability of nateglinide-hydroxypropyl-beta-cyclodextrin complex capsule in rabbits by liquid chromatographic-tandem mass spectrometry.

Xiaoyan Chen, D. Zhong, Zhonggui He, 2004, Biomedical chromatography : BMC.

Determination of misoprostol acid in human plasma by liquid chromatography coupled to tandem mass spectrometry.

Xiaoyan Chen, D. Zhong, Yueyang Zou, 2007, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Wedelolactone metabolism in rats through regioselective glucuronidation catalyzed by uridine diphosphate-glucuronosyltransferases 1As (UGT1As).

M. Zheng, Xiaoyan Chen, D. Zhong, 2016, Phytomedicine : international journal of phytotherapy and phytopharmacology.

Excretion of [3H]triptolide and its metabolites in rats after oral administration

Xiaoyan Chen, D. Zhong, Jia Liu, 2014, Acta Pharmacologica Sinica.

Development and validation of a liquid chromatographic/tandem mass spectrometric method for the determination of sertraline in human plasma.

Xiaoyan Chen, D. Zhong, Xiao-jian Dai, 2006, Rapid communications in mass spectrometry : RCM.

Simultaneous determination of imrecoxib and its two active metabolites in plasma of hepatic impairment patients by liquid chromatography-tandem mass spectrometry.

Xiaoyan Chen, D. Zhong, Xiao-jian Dai, 2019, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Metabolism and excretion of imrecoxib in rat.

Hai-Yan Xu, D. Zhong, F. Chu, 2006, Xenobiotica; the fate of foreign compounds in biological systems.

Role of rat liver cytochrome P450 3A and 2D in metabolism of imrecoxib

Hai-Yan Xu, D. Zhong, F. Chu, 2006, Acta Pharmacologica Sinica.

[Investigation on the hydroxylation metabolism of imrecoxib in vitro by using recombinant human CYPs].

Qiang Li, D. Zhong, Hai-hua Huang, 2005, Yao xue xue bao = Acta pharmaceutica Sinica.

Metabolism and excretion of imrecoxib in rat

H. Xu, D. Zhong, F. Chu, 2006 .

A sensitive LC-MS/MS method for quantifying clofarabine triphosphate concentrations in human peripheral blood mononuclear cells.

Xiaoyan Chen, D. Zhong, Yifan Zhang, 2014, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Bioavailability of Clarithromycin Cyclodextrin Ternary Complexes Upon Oral Administration to Healthy Beagle Dogs

Xiaoyan Chen, D. Zhong, Xiangrong Zhang, 2008 .

Metabolism and Pharmacokinetics of Novel Selective Vascular Endothelial Growth Factor Receptor-2 Inhibitor Apatinib in Humans

Xiaoyan Chen, D. Zhong, Xiao-jian Dai, 2013, Drug Metabolism and Disposition.

Furmonertinib (Alflutinib, AST2818) is a potential positive control drug comparable to rifampin for evaluation of CYP3A4 induction in sandwich-cultured primary human hepatocytes

D. Zhong, Zi-tao Guo, Zhendong Chen, 2021, Acta Pharmacologica Sinica.

Metabolism and Pharmacokinetics of Allitinib in Cancer Patients: The Roles of Cytochrome P450s and Epoxide Hydrolase in its Biotransformation

Xiaoyan Chen, D. Zhong, Cen Xie, 2014, Drug Metabolism and Disposition.

CYP3A4 inducer and inhibitor strongly affect the pharmacokinetics of triptolide and its derivative in rats

Xiaoyan Chen, D. Zhong, Yifan Zhang, 2018, Acta Pharmacologica Sinica.

Identification of Amiodarone Metabolites in Human Bile by Ultraperformance Liquid Chromatography/Quadrupole Time-of-Flight Mass Spectrometry

Xiaoyan Chen, D. Zhong, P. Deng, 2011, Drug Metabolism and Disposition.

Fasiglifam (TAK-875) Inhibits Hepatobiliary Transporters: A Possible Factor Contributing to Fasiglifam-Induced Liver Injury

Xiaoyan Chen, D. Zhong, Zi-tao Guo, 2015, Drug Metabolism and Disposition.

Bioanalysis of an oligonucleotide and its metabolites by liquid chromatography-tandem mass spectrometry.

Xiaoyan Chen, D. Zhong, P. Deng, 2010, Journal of pharmaceutical and biomedical analysis.

A pH-Responsive Host-guest Nanosystem Loading Succinobucol Suppresses Lung Metastasis of Breast Cancer

D. Zhong, Yaping Li, Pengcheng Zhang, 2016, Theranostics.

Influence of omeprazole on pharmacokinetics of domperidone given as free base and maleate salt in healthy Chinese patients

Xiaoyan Chen, D. Zhong, Xiao-jian Dai, 2007, Acta Pharmacologica Sinica.

Metabolite identification in preclinical and clinical phase of drug development.

D. Zhong, Zhendong Chen, X. Diao, 2021, Current drug metabolism.

Metabolism and disposition of pyrotinib in healthy male volunteers: covalent binding with human plasma protein

Xiaoyan Chen, D. Zhong, L. Miao, 2018, Acta Pharmacologica Sinica.

Development of a UHPLC-MS/MS method for the determination of plasma histamine in various mammalian species.

Xiaoyan Chen, D. Zhong, Jia Liu, 2014, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.