G. Lin

D. Schrenk, G. Lin, S. Pfuhler, 2020, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Insights into the central pathways involved in the emetic and behavioural responses to exendin-4 in the ferret

D. Yew, G. Lin, J. Rudd, 2017, Autonomic Neuroscience.

Localization of estrogen receptor ERα, ERβ and GPR30 on myenteric neurons of the gastrointestinal tract and their role in motility.

G. Lin, J. Rudd, M. Fang, 2019, General and comparative endocrinology.

Differential hypoglycaemic, anorectic, autonomic and emetic effects of the glucagon-like peptide receptor agonist, exendin-4, in the conscious telemetered ferret

N. Percie du Sert, P. Andrews, G. Lin, 2014, Journal of Translational Medicine.

A Generic Multiple Reaction Monitoring Based Approach for Plant Flavonoids Profiling Using a Triple Quadrupole Linear Ion Trap Mass Spectrometry

Yi-Tao Wang, G. Lin, Ru Yan, 2014, Journal of The American Society for Mass Spectrometry.

Comprehensive investigation and risk study on pyrrolizidine alkaloid contamination in Chinese retail honey.

G. Lin, P. Fu, Yisheng He, 2020, Environmental pollution.

Simultaneous analysis of seventeen chemical ingredients of Ligusticum chuanxiong by on-line high performance liquid chromatography-diode array detector-mass spectrometry.

G. Lin, Y. Tam, S. Li, 2003, Planta medica.

Characterization of metabolites of clozapine N-oxide in the rat by micro-column high performance liquid chromatography/mass spectrometry with electrospray interface.

K. Midha, G. Lin, G. Mckay, 1996, Journal of pharmaceutical and biomedical analysis.

Position preference on glucuronidation of mono-hydroxylflavones in human intestine.

Z. Zuo, G. Lin, Li Zhang, 2006, Life sciences.

Intestinal and hepatic glucuronidation of flavonoids.

Z. Zuo, G. Lin, Li Zhang, 2007, Molecular pharmaceutics.

A Pair of Enantiomeric Bis- seco-abietane Diterpenoids from Cryptomeria fortunei.

Sheng Yao, G. Lin, A. Mándi, 2018, Journal of natural products.

Study of the anti-proliferative effects and synergy of phthalides from Angelica sinensis on colon cancer cells.

C. Cho, G. Lin, J. Rudd, 2008, Journal of ethnopharmacology.

Adduct ion‐targeted qualitative and quantitative analysis of polyoxypregnanes by ultra‐high pressure liquid chromatography coupled with triple quadrupole mass spectrometry

G. Lin, Jiang Ma, Yang Ye, 2017, Journal of pharmaceutical and biomedical analysis.

Pharmacological effects and pharmacokinetics properties of Radix Scutellariae and its bioactive flavones.

Z. Zuo, Chen-rui Li, G. Lin, 2011, Biopharmaceutics & drug disposition.

Ultra-high-performance liquid chromatography-quadrupole/time of flight mass spectrometry based chemical profiling approach to rapidly reveal chemical transformation of sulfur-fumigated medicinal herbs, a case study on white ginseng.

Hong-Mei Zhang, G. Lin, Jun Xu, 2012, Journal of chromatography. A.

Anti-metastatic effect and mechanisms of Wenshen Zhuanggu Formula in human breast cancer cells.

G. Lin, Jiang Ma, Xiaohong Zhang, 2015, Journal of ethnopharmacology.

A novel bone targeting delivery system carrying phytomolecule icaritin for prevention of steroid-associated osteonecrosis in rats.

G. Lin, L. Qin, W. Tong, 2018, Bone.

Intestinal absorbability of three Radix Puerariae isoflavones including daidzein, daidzin and puerarin

Z. Zuo, G. Lin, Li Zhang, 2011, Chinese medicine.

Drug–Drug Interactions and Drug–Dietary Chemical Interactions

Z. Zuo, G. Lin, Na Li, 2011 .

Polyoxypregnanes as safe, potent, and specific ABCB1-inhibitory pro-drugs to overcome multidrug resistance in cancer chemotherapy in vitro and in vivo

T. Efferth, Sheng Yao, O. Kadioglu, 2021, Acta pharmaceutica Sinica. B.

In vitro and in situ evaluation of herb-drug interactions during intestinal metabolism and absorption of baicalein.

Z. Zuo, Limin Zhou, G. Lin, 2012, Journal of ethnopharmacology.

Cytotoxicity of pyrrolizidine alkaloid in human hepatic parenchymal and sinusoidal endothelial cells: Firm evidence for the reactive metabolites mediated pyrrolizidine alkaloid-induced hepatotoxicity.

G. Lin, P. Fu, Jianqing Ruan, 2016, Chemico-biological interactions.

Effect of structural modification on the gastrointestinal stability and hepatic metabolism of α-aminoxy peptides

G. Lin, Dan Yang, Chun Yin, 2012, Amino Acids.

Pharmacokinetics and Metabolism of Ligustilide, a Major Bioactive Component in Rhizoma Chuanxiong, in the Rat

G. Lin, Y. Tam, S. Li, 2008, Drug Metabolism and Disposition.

Deacetylclivorine: A Gender-Selective Metabolite of Clivorine Formed in Female Sprague-Dawley Rat Liver Microsomes

Yan Jiang, G. Lin, Jiang Zheng, 2007, Drug Metabolism and Disposition.

Low Oral Bioavailability and Pharmacokinetics of Senkyunolide A, a Major Bioactive Component in Rhizoma Chuanxiong, in the Rat

G. Lin, Y. Tam, N. Ko, 2007, Therapeutic drug monitoring.

A physiological role of glucagon-like peptide-1 receptors in the central nervous system of Suncus murinus (house musk shrew).

D. Yew, G. Lin, S. Chan, 2011, European journal of pharmacology.

Intestinal first-pass glucuronidation activities of selected dihydroxyflavones.

Z. Zuo, G. Lin, Y. Wong, 2009, International journal of pharmaceutics.

Separation of emetic and anorexic responses of exendin-4, a GLP-1 receptor agonist in Suncus murinus (house musk shrew)

D. Yew, G. Lin, S. Chan, 2013, Neuropharmacology.

Addition of Berberine to 5-Aminosalicylic Acid for Treatment of Dextran Sulfate Sodium-Induced Chronic Colitis in C57BL/6 Mice

G. Lin, Hai-tao Xiao, Cheng-Yuan Lin, 2015, PloS one.

Novel Insights into Pyrrolizidine Alkaloid Toxicity and Implications for Risk Assessment: Occurrence, Genotoxicity, Toxicokinetics, Risk Assessment–AWorkshop Report

D. Schrenk, G. Lin, S. Pfuhler, 2021 .

Novel Insights into Pyrrolizidine Alkaloid Toxicity and Implications for Risk Assessment: Occurrence, Genotoxicity, Toxicokinetics, Risk Assessment–A Workshop Report

D. Schrenk, G. Lin, S. Pfuhler, 2021, Planta Medica.

Contamination of hepatotoxic pyrrolizidine alkaloids in retail honey in China

G. Lin, P. Fu, Yisheng He, 2018 .

Phyllanthus urinaria ameliorates the severity of nutritional steatohepatitis both in vitro and in vivo

Jun Yu, J. Sung, G. Lin, 2007, Hepatology.

Metabolism-mediated cytotoxicity and genotoxicity of pyrrolizidine alkaloids

G. Lin, Yisheng He, Jiang Ma, 2021, Archives of Toxicology.

Pyrrole-protein adducts – A biomarker of pyrrolizidine alkaloid-induced hepatotoxicity

G. Lin, P. Fu, Q. Xia, 2018, Journal of food and drug analysis.

Hepatic Metabolism and Disposition of Baicalein via the Coupling of Conjugation Enzymes and Transporters—In Vitro and In Vivo Evidences

Z. Zuo, Chen-rui Li, G. Lin, 2011, The AAPS Journal.

A Catenary Model to Study Transport and Conjugation of Baicalein, a Bioactive Flavonoid, in the Caco-2 Cell Monolayer: Demonstration of Substrate Inhibition

Z. Zuo, G. Lin, K. Pang, 2008, Journal of Pharmacology and Experimental Therapeutics.

Intestinal and hepatic biotransformation of pyrrolizidine alkaloid N-oxides to toxic pyrrolizidine alkaloids

G. Lin, P. Fu, Jianqing Ruan, 2019, Archives of Toxicology.

Characterization of liver injury induced by a pyrrolizidine alkaloid in rats.

G. Lin, Yisheng He, Jiang Ma, 2021, Phytomedicine : international journal of phytotherapy and phytopharmacology.

Pulmonary toxicity is a common phenomenon of toxic pyrrolizidine alkaloids.

G. Lin, P. Fu, Yisheng He, 2020, Journal of environmental science and health. Part C, Toxicology and carcinogenesis.

The effects of pretreatment with glycyrrhizin and glycyrrhetinic acid on the retrorsine-induced hepatotoxicity in rats.

G. Lin, I. Nnane, T. Cheng, 1999, Toxicon : official journal of the International Society on Toxinology.

Action of anti-tussive drugs on the emetic reflex of Suncus murinus (house musk shrew).

Ping Li, G. Lin, S. Chan, 2007, European journal of pharmacology.

First evidence of pyrrolizidine alkaloid N-oxide-induced hepatic sinusoidal obstruction syndrome in humans

G. Lin, P. Fu, Jianqing Ruan, 2017, Archives of Toxicology.

Dual-Functional Liposomes with Carbonic Anhydrase IX Antibody and BR2 Peptide Modification Effectively Improve Intracellular Delivery of Cantharidin to Treat Orthotopic Hepatocellular Carcinoma Mice

G. Lin, Aiping Lu, Hongcan Shi, 2019, Molecules.

Isolation and Stereochemistry of Two New Alkaloids from Stemona tuberosa

G. Lin, W. Ye, P. But, 2002 .

Polyoxypregnane steroids from the stems of Marsdenia tenacissima.

Sheng Yao, G. Lin, K. To, 2014, Journal of natural products.

Oral absorption and antitussive activity of tuberostemonine alkaloids from the roots of Stemona tuberosa.

Z. Zuo, G. Lin, Yang Ye, 2009, Planta medica.

Croomine- and tuberostemonine-type alkaloids from roots of Stemona tuberosa and their antitussive activity

G. Lin, J. Rudd, C. Ke, 2008 .

Relaxation effects of ligustilide and senkyunolide A, two main constituents of Ligusticum chuanxiong, in rat isolated aorta.

G. Lin, Sunny Sun-Kin Chan, T. Cheng, 2007, Journal of ethnopharmacology.

Triterpenoid saponins profiling by adducts-targeted neutral loss triggered enhanced resolution and product ion scanning using triple quadrupole linear ion trap mass spectrometry.

Yi-Tao Wang, G. Lin, Ru Yan, 2014, Analytica chimica acta.

Pyrrolizidine alkaloid-derived DNA adducts as a common biological biomarker of pyrrolizidine alkaloid-induced tumorigenicity.

G. Lin, D. Doerge, P. Fu, 2013, Chemical research in toxicology.

Ginsenosides facilitate the anti-cancer efficacy of cyclophosphamide via modulating intestinal bacteria and alleviating intestinal mucositis in mammary carcinoma mice

G. Lin, Yisheng He, Jiang Ma, 2019 .

In vitro Tracheobronchial Relaxation of Fritillaria Alkaloids

Y. Kwan, G. Lin, S. Chan, 2011 .

The dual roles of ginsenosides in improving the anti-tumor efficiency of cyclophosphamide in mammary carcinoma mice.

G. Lin, Yisheng He, Jiang Ma, 2020, Journal of ethnopharmacology.

Identification of lactams as in vitro metabolites of piperidine-type phenothiazine antipsychotic drugs.

K. Midha, G. Lin, E. Hawes, 1996, Journal of pharmaceutical and biomedical analysis.

Authentication and Quality Assessment of the Antitussive Herb Baibu (Radix Stemonae)

P. Shaw, G. Lin, P. But, 2012 .

Vatalanib sensitizes ABCB1 and ABCG2-overexpressing multidrug resistant colon cancer cells to chemotherapy under hypoxia.

F. Wang, G. Lin, K. To, 2015, Biochemical pharmacology.

Olvanil, a non-pungent vanilloid enhances the gastrointestinal toxicity of cisplatin in the ferret.

N. Percie du Sert, P. Andrews, G. Lin, 2010, Toxicology letters.

Metabolism of piperidine-type phenothiazine antipsychotic agents. IV. Thioridazine in dog, man and rat.

K. Midha, G. Lin, G. Mckay, 1993, Xenobiotica; the fate of foreign compounds in biological systems.

Selective and sensitive determination of bis(7)-tacrine, a high erythrocyte binding acetylcholinesterase inhibitor, in rat plasma by high-performance liquid chromatography-tandem mass spectrometry.

Z. Zuo, Y. Pang, G. Lin, 2008, Biomedical chromatography : BMC.

Lung injury induced by pyrrolizidine alkaloids depends on metabolism by hepatic cytochrome P450s and blood transport of reactive metabolites

G. Lin, Yisheng He, Jiang Ma, 2020, Archives of Toxicology.

Blood pyrrole-protein adducts as a diagnostic and prognostic index in pyrrolizidine alkaloid-hepatic sinusoidal obstruction syndrome

G. Lin, Jianqing Ruan, C. Ke, 2015, Drug design, development and therapy.

Development of a two-layer transwell co-culture model for the in vitro investigation of pyrrolizidine alkaloid-induced hepatic sinusoidal damage.

G. Lin, Jiang Ma, Yao Lu, 2019, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Fasting augments pyrrolizidine alkaloid-induced hepatotoxicity

G. Lin, Yisheng He, Chunyuan Zhang, 2021, Archives of toxicology.

Assessment of pyrrolizidine alkaloid-induced toxicity in an in vitro screening model.

G. Lin, Na Li, W. L. T. Kan, 2013, Journal of ethnopharmacology.

Mechanisms underlying the vasorelaxing effects of butylidenephthalide, an active constituent of Ligusticum chuanxiong, in rat isolated aorta.

G. Lin, R. Jones, A. Choi, 2006, European journal of pharmacology.

Photoirradiation of dehydropyrrolizidine alkaloids--formation of reactive oxygen species and induction of lipid peroxidation.

G. Lin, P. Fu, Q. Xia, 2011, Toxicology letters.

Developing urinary pyrrole–amino acid adducts as non-invasive biomarkers for identifying pyrrolizidine alkaloids-induced liver injury in human

G. Lin, P. Fu, Q. Xia, 2021, Archives of Toxicology.

Phosphocreatine attenuates Gynura segetum-induced hepatocyte apoptosis via a SIRT3-SOD2-mitochondrial reactive oxygen species pathway

G. Lin, C. Ke, Yang Ye, 2019, Drug design, development and therapy.

1-Formyl-7-hydroxy-6,7-dihydro-5 H-pyrrolizine (1-CHO-DHP): A Potential Proximate Carcinogenic Metabolite of Pyrrolizidine Alkaloids.

G. Lin, P. Fu, Q. Xia, 2019, Chemical research in toxicology.

Phosphocreatine attenuates Gynura segetum -induced hepatocyte apoptosis via a SIRT3-SOD2-mitochondrial reactive oxygen species pathway

G. Lin, C. Ke, Yang Ye, 2019 .

Characteristic ion clusters as determinants for the identification of pyrrolizidine alkaloid N-oxides in pyrrolizidine alkaloid-containing natural products using HPLC-MS analysis.

G. Lin, P. Fu, Q. Xia, 2012, Journal of mass spectrometry : JMS.

A new approach for simultaneous screening and quantification of toxic pyrrolizidine alkaloids in some potential pyrrolizidine alkaloid-containing plants by using ultra performance liquid chromatography-tandem quadrupole mass spectrometry.

G. Lin, P. Fu, S. Li, 2010, Analytica chimica acta.

Identification of five hepatotoxic pyrrolizidine alkaloids in a commonly used traditional Chinese medicinal herb, Herba Senecionis scandentis (Qianliguang).

Zhong-Zhen Zhao, G. Lin, Zhi-Hong Jiang, 2008, Rapid communications in mass spectrometry : RCM.

Metabolic formation of DHP-derived DNA adducts from a representative otonecine type pyrrolizidine alkaloid clivorine and the extract of Ligularia hodgsonnii hook.

G. Lin, P. Fu, Q. Xia, 2004, Chemical research in toxicology.

Pyrrolizidine Alkaloids—Genotoxicity, Metabolism Enzymes, Metabolic Activation, and Mechanisms

Ge Lin, Peter P Fu, G. Lin, 2004, Drug metabolism reviews.

Characterization of rat liver microsomal metabolites of clivorine, an hepatotoxic otonecine-type pyrrolizidine alkaloid.

G. Lin, E. Hawes, Yan-yan Cui, 2000, Drug metabolism and disposition: the biological fate of chemicals.

Pyrrolizidine alkaloids - Tumorigenic components in Chinese herbal medicines and dietary supplements

G. Lin, P. Fu, Q. Xia, 2020 .

Lysine Adduction by Reactive Metabolite(s) of Monocrotaline.

G. Lin, Jiang Zheng, Kai Wang, 2016, Chemical research in toxicology.

Pyrrole-Hemoglobin Adducts, a More Feasible Potential Biomarker of Pyrrolizidine Alkaloid Exposure.

Sheng Yao, G. Lin, P. Fu, 2019, Chemical research in toxicology.

Tu-San-Qi (Gynura japonica): the culprit behind pyrrolizidine alkaloid-induced liver injury in China

G. Lin, P. Fu, Chunyuan Zhang, 2020, Acta Pharmacologica Sinica.

Anti-inflammatory Inositol Derivatives from the Whole Plant of Inula cappa.

Sheng Yao, Linyin Feng, G. Lin, 2015, Journal of natural products.

Metabolic conversion from co-existing ingredient leading to significant systemic exposure of Z-butylidenephthalide, a minor ingredient in Chuanxiong Rhizoma in rats.

G. Lin, Y. Tam, Bin Ma, 2012, Current drug metabolism.

Antitussive activity of Stemona alkaloids from Stemona tuberosa.

G. Lin, P. But, Hoi-sing Chung, 2003, Planta medica.

Alkaloids from roots of Stemona sessilifolia and their antitussive activities.

G. Lin, J. Rudd, C. Ke, 2009, Planta medica.

Antitussive stemoninine alkaloids from the roots of Stemona tuberosa.

G. Lin, J. Rudd, C. Ke, 2008, Journal of natural products.

Stemoninines from the roots of Stemona tuberosa.

G. Lin, C. Ke, Chunping Tang, 2006, Journal of natural products.

Synthesis of the piperidinone metabolites of piperidine type phenothiazine antipsychotic drugs via ruthenium tetroxide oxidation

K. Midha, G. Lin, E. Hawes, 1991 .

Synthesis of the N-oxides of phenothiazine antipsychotic agents.

K. Midha, J. Hubbard, G. Lin, 1993, Journal of pharmaceutical sciences.

Reversal of P-glycoprotein-mediated multidrug resistance by a synthetic α-aminoxy peptidomimetic.

G. Lin, Dan Yang, K. To, 2012, International journal of pharmaceutics.

Effect of structural modification on the gastrointestinal stability and hepatic metabolism of α-aminoxy peptides

G. Lin, Dan Yang, Chun Yin, 2012, Amino Acids.

Effect of structural modification of α-aminoxy peptides on their intestinal absorption and transport mechanism.

G. Lin, Dan Yang, Na Li, 2011, Molecular pharmaceutics.

Lack of metabolic activation and predominant formation of an excreted metabolite of nontoxic platynecine-type pyrrolizidine alkaloids.

G. Lin, Jianqing Ruan, Yang Ye, 2014, Chemical research in toxicology.

Microsomal formation of a pyrrolic alcohol glutathione conjugate of clivorine. Firm evidence for the formation of a pyrrolic metabolite of an otonecine-type pyrrolizidine alkaloid.

G. Lin, G Lin, Y Y Cui, 1998, Drug metabolism and disposition: the biological fate of chemicals.

Extraordinary metabolic stability of peptides containing α-aminoxy acids

G. Lin, Dan Yang, Fei Chen, 2012, Amino Acids.

The first phytochemical investigation of Rhododendron websterianum : triterpenoids and their cytotoxic activity

Sheng Yao, G. Lin, C. Ke, 2018, Phytochemistry Letters.

Sulfur Fumigation Processing of Traditional Chinese Medicinal Herbs: Beneficial or Detrimental?

G. Lin, Bin Ma, W. L. T. Kan, 2011, Front. Pharmacol..

Evidence on Integrating Pharmacokinetics to Find Truly Therapeutic Agent for Alzheimer's Disease: Comparative Pharmacokinetics and Disposition Kinetics Profiles of Stereoisomers Isorhynchophylline and Rhynchophylline in Rats

G. Lin, Chunyuan Zhang, Zhi-xiu Lin, 2019, Evidence-based complementary and alternative medicine : eCAM.

Diterpenoids from the flowers of Rhododendron molle.

Sheng Yao, G. Lin, C. Ke, 2014, Journal of natural products.

Chromatographic analysis of Fritillaria isosteroidal alkaloids, the active ingredients of Beimu, the antitussive traditional Chinese medicinal herb.

S. Li, G. Lin, P. Li, 2001, Journal of chromatography. A.

Transporter modulation by Chinese herbal medicines and its mediated pharmacokinetic herb-drug interactions.

G. Lin, Jiang Ma, Yang Ye, 2016, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Involvement of UDP-Glucuronosyltransferases in the Extensive Liver and Intestinal First-Pass Metabolism of Flavonoid Baicalein

Z. Zuo, G. Lin, Li Zhang, 2006, Pharmaceutical Research.

Surface plasmon enhanced drug efficacy using core-shell Au@SiO2 nanoparticle carrier.

G. Lin, Quan Li, Zhiqin Chu, 2013, Nanoscale.

Drug delivery system targeting advanced hepatocellular carcinoma: Current and future.

G. Lin, Aiping Lu, Xue Zhang, 2016, Nanomedicine : nanotechnology, biology, and medicine.

Decomposition of clozapine N-oxide in the qualitative and quantitative analysis of clozapine and its metabolites.

K. Midha, J. Hubbard, G. Lin, 1994, Journal of pharmaceutical sciences.

The Actions of Centrally Administered Nesfatin-1 on Emesis, Feeding, and Locomotor Activity in Suncus murinus (House Musk Shrew)

I. Sakata, G. Lin, T. Sakai, 2022, Frontiers in Pharmacology.

Antitumor effects of novel compound, guttiferone K, on colon cancer by p21Waf1/Cip1‐mediated G0/G1 cell cycle arrest and apoptosis

C. Cho, G. Lin, K. To, 2013, International journal of cancer.

High performance liquid chromatographic analysis of a novel aminoalkylpyridine anticonvulsant 2-(4-chlorophenyl)amino-2-(4-pyridyl)ethane.

A. Chow, G. Lin, I. Nnane, 1998, Journal of pharmaceutical and biomedical analysis.

Circumvention of multi-drug resistance of cancer cells by Chinese herbal medicines

K. To, G. Lin, Kenneth K. W. To, 2010, Chinese medicine.

Cytotoxic Germacrane-Type Sesquiterpene Lactones from the Whole Plant of Carpesium lipskyi.

Sheng Yao, G. Lin, C. Ke, 2019, Journal of natural products.

The role of formation of pyrrole–ATP synthase subunit beta adduct in pyrrolizidine alkaloid-induced hepatotoxicity

G. Lin, P. Fu, Jiang Ma, 2018, Archives of Toxicology.

Role of Intestinal First-Pass Metabolism of Baicalein in its Absorption Process

Z. Zuo, G. Lin, Q. Chang, 2005, Pharmaceutical Research.

Cytotoxic acylphloroglucinol derivatives from the twigs of Garcinia cowa.

Ge Lin, Yan Zhou, Gang Xu, 2010, Journal of natural products.

Reversal of multidrug resistance by Marsdenia tenacissima and its main active ingredients polyoxypregnanes.

T. Efferth, Sheng Yao, O. Kadioglu, 2017, Journal of ethnopharmacology.

Mutational Signature Analysis Reveals Widespread Contribution of Pyrrolizidine Alkaloid Exposure to Human Liver Cancer

S. Tsui, K. Man, G. Lin, 2021, Hepatology.

Post-harvest alteration of the main chemical ingredients in Ligusticum chuanxiong Hort. (Rhizoma Chuanxiong).

G. Lin, Y. Tam, S. Li, 2007, Chemical & pharmaceutical bulletin.

Pyrrolizidine Alkaloid-Induced Hepatotoxicity Associated with the Formation of Reactive Metabolite-Derived Pyrrole–Protein Adducts

W. Chan, G. Lin, Jiang Ma, 2021, Toxins.

Immunoassay approach for diagnosis of exposure to pyrrolizidine alkaloids

G. Lin, Fan Zhang, Jiang Zheng, 2017, Journal of environmental science and health. Part C, Environmental carcinogenesis & ecotoxicology reviews.

Pyrrolizidine Alkaloid-Protein Adducts: Potential Non-invasive Biomarkers of Pyrrolizidine Alkaloid-Induced Liver Toxicity and Exposure.

F. Beland, G. Lin, P. Fu, 2016, Chemical research in toxicology.

Blood Pyrrole-Protein Adducts—A Biomarker of Pyrrolizidine Alkaloid-Induced Liver Injury in Humans

G. Lin, P. Fu, Jianqing Ruan, 2015, Journal of environmental science and health. Part C, Environmental carcinogenesis & ecotoxicology reviews.

Proteomic study of pyrrolizidine alkaloid-induced hepatic sinusoidal obstruction syndrome in rats.

W. Chan, G. Lin, W. Tai, 2015, Chemical research in toxicology.

Metabolic activation of pyrrolizidine alkaloids: insights into the structural and enzymatic basis.

Ge Lin, Yang Ye, Jianqing Ruan, 2014, Chemical research in toxicology.

Pelitinib (EKB‐569) targets the up‐regulation of ABCB1 and ABCG2 induced by hyperthermia to eradicate lung cancer

Liwu Fu, G. Lin, K. To, 2015, British journal of pharmacology.

Clinical application of pyrrole–hemoglobin adducts as a biomarker of pyrrolizidine alkaloid exposure in humans

G. Lin, Yisheng He, Chunyuan Zhang, 2020, Archives of toxicology.

Dual-ligand modified liposomes provide effective local targeted delivery of lung-cancer drug by antibody and tumor lineage-homing cell-penetrating peptide

Hubiao Chen, G. Lin, Ge Zhang, 2018, Drug delivery.

[Study on fingerprint of rhizoma chuanxiong by HPLC-DAD-MS].

G. Lin, Y. Tam, S. Li, 2004, Yao xue xue bao = Acta pharmaceutica Sinica.

Comparison of Intestinal Absorption and Disposition of Structurally Similar Bioactive Flavones in Radix Scutellariae

Z. Zuo, Chen-rui Li, G. Lin, 2012, The AAPS Journal.

Mechanistic study on the intestinal absorption and disposition of baicalein.

Z. Zuo, G. Lin, P. Krajcsi, 2007, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Genotoxic Pyrrolizidine Alkaloids — Mechanisms Leading to DNA Adduct Formation and Tumorigenicity

G. Lin, P. Fu, Q. Xia, 2002 .

The Potential of Liposomes with Carbonic Anhydrase IX to Deliver Anticancer Ingredients to Cancer Cells in Vivo

G. Lin, L. Qin, Aiping Lu, 2014, International journal of molecular sciences.

Antibody-based detection of lysine modification of hepatic protein in mice treated with retrorsine.

G. Lin, Fan Zhang, Jiang Zheng, 2020, Journal of environmental science and health. Part C, Toxicology and carcinogenesis.

Controllable drug release and simultaneously carrier decomposition of SiO2-drug composite nanoparticles.

G. Lin, Quan Li, Chunyuan Zhang, 2013, Journal of the American Chemical Society.

Pyrrolizidine alkaloid-derived DNA adducts are common toxicological biomarkers of pyrrolizidine alkaloid N-oxides

G. Lin, P. Fu, Q. Xia, 2017, Journal of food and drug analysis.

Pulmonary delivery of triptolide-loaded liposomes decorated with anti-carbonic anhydrase IX antibody for lung cancer therapy

Hubiao Chen, G. Lin, Ge Zhang, 2017, Scientific Reports.

Quantitation of DNA reactive pyrrolic metabolites of senecionine - A carcinogenic pyrrolizidine alkaloid by LC/MS/MS analysis.

Q. Shi, G. Lin, P. Fu, 2020, Journal of food and drug analysis.

Primary and secondary pyrrolic metabolites of pyrrolizidine alkaloids form DNA adducts in human A549 cells.

W. Tolleson, G. Lin, P. Fu, 2019, Toxicology in vitro : an international journal published in association with BIBRA.

Unambiguous observation of shape effects on cellular fate of nanoparticles

Ge Lin, Huan-Cheng Chang, Chia-Yi Fang, 2014, Scientific Reports.

Species differences in the in vitro metabolic activation of the hepatotoxic pyrrolizidine alkaloid clivorine.

G. Lin, Xiao-quan Liu, Yan-yan Cui, 2002, Chemical research in toxicology.

Identification and quantification of baicalein, wogonin, oroxylin A and their major glucuronide conjugated metabolites in rat plasma after oral administration of Radix scutellariae product.

Z. Zuo, Chen-rui Li, G. Lin, 2011, Journal of pharmaceutical and biomedical analysis.

Simultaneous determination of amino acids in discrete brain areas in Suncus murinus by high performance liquid chromatography with electrochemical detection.

D. Yew, G. Lin, S. Chan, 2010, Journal of pharmaceutical and biomedical analysis.

The metabolism of piperidine-type phenothiazine antipsychotic agents. II. Sulforidazine in dog and human.

K. Midha, G. Lin, G. Mckay, 1993, Xenobiotica; the fate of foreign compounds in biological systems.

Gender differences in microsomal metabolic activation of hepatotoxic clivorine in rat.

G. Lin, Xiao-quan Liu, Yan-yan Cui, 2003, Chemical research in toxicology.

Absorption difference between hepatotoxic pyrrolizidine alkaloids and their N-oxides - Mechanism and its potential toxic impact.

G. Lin, Jianqing Ruan, Chunyuan Zhang, 2019, Journal of ethnopharmacology.

Chemical diversity investigation of hepatotoxic pyrrolizidine alkaloids in Qianliguang (Senecio scandens) and related species by UHPLC-QTOF-MS1

G. Lin, P. Fu, Jianqing Ruan, 2015 .

Gastric myoelectric activity during cisplatin-induced acute and delayed emesis reveals a temporal impairment of slow waves in ferrets: effects not reversed by the GLP-1 receptor antagonist, exendin (9-39)

D. Yew, P. Andrews, G. Lin, 2017, Oncotarget.

Isorhynchophylline ameliorates cognitive impairment via modulating amyloid pathology, tau hyperphosphorylation and neuroinflammation: Studies in a transgenic mouse model of Alzheimer’s disease

Yue Liu, K. Tsim, Yifan Han, 2019, Brain, Behavior, and Immunity.

Toxicoproteomic assessment of liver responses to acute pyrrolizidine alkaloid intoxication in rats

W. Chan, G. Lin, W. Tai, 2018, Journal of environmental science and health. Part C, Environmental carcinogenesis & ecotoxicology reviews.

Simultaneous quantification of 12 bioactive components of Ligusticum chuanxiong Hort. by high-performance liquid chromatography.

G. Lin, Y. Tam, S. Li, 2005, Journal of pharmaceutical and biomedical analysis.

The key role of gut–liver axis in pyrrolizidine alkaloid-induced hepatotoxicity and enterotoxicity

G. Lin, Yisheng He, Jiang Ma, 2021, Acta pharmaceutica Sinica. B.

The metabolism of piperidine-type phenothiazine antipsychotic agents. I. Sulforidazine in the rat.

G McKay, K. Midha, G. Lin, 1992, Xenobiotica; the fate of foreign compounds in biological systems.

The metabolism of piperidine-type phenothiazine antipsychotic agents. III. Mesoridazine in dog, human and rat.

K. Midha, G. Lin, G. Mckay, 1993, Xenobiotica; the fate of foreign compounds in biological systems.

Development of a high performance liquid chromatography-tandem mass method for determination of bis(7)-tacrine, a promising anti-Alzheimer's dimer, in rat blood.

Yitao Wang, Y. Pang, Wenming Li, 2007, Journal of pharmaceutical and biomedical analysis.

Characterization of two structural forms of otonecine-type pyrrolizidine alkaloids from Ligularia hodgsonii by NMR spectroscopy.

G. Lin, X. Zhao, K. Chatson, 2000, Journal of natural products.

UVA Photoirradiation of Oxygenated Benz[a]anthracene and 3-Methylcholanthene - Generation of Singlet Oxygen and Induction of Lipid Peroxidation

Hongtao Yu, G. Lin, P. Fu, 2008, International journal of environmental research and public health.

Naturally occurring proteinaceous nanoparticles in Coptidis Rhizoma extract act as concentration-dependent carriers that facilitate berberine absorption

G. Lin, Bing-Liang Ma, Chun Yin, 2016, Scientific Reports.

A novel ultra-performance liquid chromatography hyphenated with quadrupole time of flight mass spectrometry method for rapid estimation of total toxic retronecine-type of pyrrolizidine alkaloids in herbs without requiring corresponding standards.

G. Lin, P. Fu, Jianqing Ruan, 2016, Food chemistry.

Qianliguang (Senecio scandens) safety dilemma: dose is the key?

Zhong-Zhen Zhao, W. Chan, G. Lin, 2009, Planta medica.

Double loaded self-decomposable SiO₂ nanoparticles for sustained drug release.

G. Lin, Quan Li, Jiang Ma, 2015, Nanoscale.

The e ects of pretreatment with glycyrrhizin and glycyrrhetinic acid on the retrorsine-induced hepatotoxicity in rats

G. Lin, I. Nnane, T. Cheng, 1999 .

Rapid endosomal escape of prickly nanodiamonds: implications for gene delivery

Ge Lin, Huan-Cheng Chang, Saisai Zhao, 2015, Scientific Reports.

Intestinal absorption of Stemona alkaloids in a Caco-2 cell model.

Z. Zuo, G. Lin, Li Zhang, 2006, Planta medica.

The extraction of imperialine and imperialine-3 beta-glucoside from Fritillaria pallidiflora Schrenk and quantitative determination by HPLC-evaporative light scattering detection.

Ping Li, G. Lin, S. Li, 2002, Phytochemical analysis : PCA.

Polyoxypregnane steroids with an open-chain sugar moiety from Marsdenia tenacissima and their chemoresistance reversal activity.

Sheng Yao, G. Lin, K. To, 2016, Phytochemistry.

Investigation of association of chemical profiles with the tracheobronchial relaxant activity of Chinese medicinal herb Beimu derived from various Fritillaria species.

Ping Li, P. Shaw, G. Lin, 2018, Journal of ethnopharmacology.

Cassane Diterpenoids from the Pericarps of Caesalpinia bonduc.

Sheng Yao, G. Lin, Chunping Tang, 2016, Journal of natural products.

Centrally located GLP-1 receptors modulate gastric slow waves and cardiovascular function in ferrets consistent with the induction of nausea

D. Yew, P. Andrews, G. Lin, 2017, Neuropeptides.

Pharmacokinetic interactions among major bioactive components in Radix Scutellariae via metabolic competition

Z. Zuo, Chen-rui Li, G. Lin, 2012, Biopharmaceutics & drug disposition.

Structure–activity relationships of the glucuronidation of flavonoids by human glucuronosyltransferases

Z. Zuo, G. Lin, Y. Wong, 2009, Expert opinion on drug metabolism & toxicology.

Pitfalls of the selection of chemical markers for the quality control of medicinal herbs

G. Lin, S. Li, Sunny Sun-Kin Chan, 2020 .

Evaluation of the first-pass glucuronidation of selected flavones in gut by Caco-2 monolayer model.

Z. Zuo, G. Lin, Li Zhang, 2004, Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques.

Influence of mefenamic acid on the intestinal absorption and metabolism of three bioactive flavones in Radix Scutellariae and potential pharmacological impact

Z. Zuo, Q. Mei, Chen-rui Li, 2014, Pharmaceutical biology.

Mitochondrial membrane potential played crucial roles in the accumulation of berberine in HepG2 cells

G. Lin, Chang Liu, Jiquan Zhang, 2019, Bioscience reports.

Editorial: Pharmacokinetics of herbal medicines and herb-drug interactions

G. Lin, Guangbo Ge, Chuang Lu, 2022, Frontiers in Pharmacology.

Three new dimeric diterpenes from Rhododendron molle

Sheng Yao, G. Lin, Chunping Tang, 2017 .

Birhodomolleins D and E, two new dimeric grayanane diterpenes with a 3-O-2′ linkage from the fruits of Rhododendron pumilum

Sheng Yao, G. Lin, Chunping Tang, 2018 .

Soy flavonoids prevent cognitive deficits induced by intra-gastrointestinal administration of beta-amyloid.

E. Ponomarev, G. Lin, J. Rudd, 2020, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Sulfur fumigation reducing systemic exposure of ginsenosides and weakening immunomodulatory activity of ginseng.

G. Lin, Song-Lin Li, He Zhu, 2017, Journal of ethnopharmacology.

Blood Pyrrole–DNA Adducts Define the Early Tumorigenic Risk in Patients with Pyrrolizidine Alkaloid-Induced Liver Injury

G. Lin, P. Fu, Q. Xia, 2021 .

Extraction of the Main Ingredients from Chuanxiong by CO 2 Supercritical Fluid Extraction

G. Lin, S. Li, Ru Yan, 2012 .

High-performance liquid chromatographic method for simultaneous determination of baicalein and baicalein 7-glucuronide in rat plasma.

Z. Zuo, G. Lin, Li Zhang, 2004, Journal of pharmaceutical and biomedical analysis.

Polyethylene glycol 400 (PEG400) affects the systemic exposure of oral drugs based on multiple mechanisms: taking berberine as an example

G. Lin, Bing-Liang Ma, Yueming Ma, 2017 .

Centrally located GLP-1 receptors modulate gastric slow waves and cardiovascular function in ferrets consistent with the induction of nausea

D. Yew, P. Andrews, G. Lin, 2017, Neuropeptides.