P. Wangemann

F. Trepiccione, B. Villoutreix, A. Griffith, 2017, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

Mouse Models Reveal the Role of Pendrin in the Inner Ear

A. Griffith, P. Wangemann, 2017 .

Slc26a4 expression prevents fluctuation of hearing in a mouse model of large vestibular aqueduct syndrome

A. Griffith, P. Wangemann, Hui Cheng, 2016, Neuroscience.

Progressive irreversible hearing loss is caused by stria vascularis degeneration in an Slc26a4-insufficient mouse model of large vestibular aqueduct syndrome

A. Griffith, P. Wangemann, A. Nishio, 2015, Neuroscience.

Mouse Models for Pendrin-Associated Loss of Cochlear and Vestibular Function

P. Wangemann, 2013, Cellular Physiology and Biochemistry.

SLC 26 A 4 Targeted to the Endolymphatic Sac Rescues Hearing and Balance in Slc 26 a 4 Mutant Mice

A. Griffith, R. Chambrey, P. Wangemann, 2013 .

Endolymphatic Na+ and K+ Concentrations during Cochlear Growth and Enlargement in Mice Lacking Slc26a4/pendrin

P. Wangemann, D. C. Marcus, Xiangming Li, 2013, PloS one.

SLC26A4 Targeted to the Endolymphatic Sac Rescues Hearing and Balance in Slc26a4 Mutant Mice

A. Griffith, R. Chambrey, P. Wangemann, 2013, PLoS genetics.

Developmental expression of SLC26A4 (Pendrin) during amelogenesis in developing rodent teeth

P. Wangemann, B. Zandieh-Doulabi, A. Bronckers, 2012 .

The Role of Pendrin in the Development of the Murine Inner Ear

P. Wangemann, 2011, Cellular Physiology and Biochemistry.

Mouse model of enlarged vestibular aqueducts defines temporal requirement of Slc26a4 expression for hearing acquisition.

R. Petralia, A. Griffith, T. Friedman, 2011, The Journal of clinical investigation.

Hearing loss associated with enlargement of the vestibular aqueduct: Mechanistic insights from clinical phenotypes, genotypes, and mouse models

A. Griffith, P. Wangemann, 2011, Hearing Research.

Epithelial Cell Stretching and Luminal Acidification Lead to a Retarded Development of Stria Vascularis and Deafness in Mice Lacking Pendrin

P. Wangemann, Hyoung-Mi Kim, 2011, PloS one.

Failure of Fluid Absorption in the Endolymphatic Sac Initiates Cochlear Enlargement that Leads to Deafness in Mice Lacking Pendrin Expression

P. Wangemann, Hyoung-Mi Kim, 2010, PloS one.

Free radical stress-mediated loss of Kcnj10 protein expression in stria vascularis contributes to deafness in Pendred syndrome mouse model.

P. Wangemann, Ruchira Singh, 2008, American journal of physiology. Renal physiology.

Lack of pendrin HCO3- transport elevates vestibular endolymphatic [Ca2+] by inhibition of acid-sensitive TRPV5 and TRPV6 channels.

E. Green, P. Wangemann, S. Wall, 2007, American journal of physiology. Renal physiology.

Macrophage invasion contributes to degeneration of stria vascularis in Pendred syndrome mouse model

E. Green, P. Wangemann, S. Fleming, 2006, BMC medicine.

Loss of KCNJ10 protein expression abolishes endocochlear potential and causes deafness in Pendred syndrome mouse model

E. Green, P. Wangemann, Tao Wu, 2004, BMC medicine.

The gastric H,K-ATPase in stria vascularis contributes to pH regulation of cochlear endolymph but not to K secretion

P. Wangemann, D. C. Marcus, H. Miyazaki, 2016, BMC Physiology.

SLC26A4 Genotypes and Phenotypes Associated with Enlargement of the Vestibular Aqueduct

T. Shawker, J. Butman, A. Griffith, 2011, Cellular Physiology and Biochemistry.

Glucocorticoids stimulate cation absorption by semicircular canal duct epithelium via epithelial sodium channel.

P. Wangemann, P. Milhaud, Joel D. Sanneman, 2004, American journal of physiology. Renal physiology.

Cochlear blood flow regulation.

Philine Wangemann, P. Wangemann, 2002, Advances in oto-rhino-laryngology.

Evidence for a Calcium-Sensing Receptor in the Vascular Smooth Muscle Cells of the Spiral Modiolar Artery

P. Wangemann, M. Scofield, K. Wonneberger, 2000, The Journal of Membrane Biology.

The isolated in vitro perfused spiral modiolar artery: pressure dependence of vasoconstriction

P. Wangemann, Daniel D. Gruber, 1998, Hearing Research.

α1A-Adrenergic receptors mediate vasoconstriction of the isolated spiral modiolar artery in vitro

P. Wangemann, M. Scofield, M. Shimozono, 1998, Hearing Research.

Ryanodine-induced vasoconstriction of the gerbil spiral modiolar artery depends on the Ca2+ sensitivity but not on Ca2+ sparks or BK channels

P. Wangemann, K. Reimann, G. Krishnamoorthy, 2016, BMC Physiology.

Molecular and pharmacological characteristics of the gerbil α1a-adrenergic receptor

P. Wangemann, M. Scofield, C. Bockman, 2012, Hearing Research.

A Claudin-9–Based Ion Permeability Barrier Is Essential for Hearing

P. Wangemann, S. H. Kim, R. Nessler, 2009, PLoS genetics.

[Potassium ion secretion and generation of the endocochlear potential in the stria vascularis].

P. Wangemann, 1997, HNO.

KCNJ10(Kir4.1)カリウムチャンネルノックアウトはか牛内直流電位を消失させる

P. Wangemann, P. Kofuji, C. MarcusD, 2002 .

CRISPR/Cas9-Induced Mutagenesis Corroborates the Role of Transportin-SR2 in HIV-1 Nuclear Import

K. Steel, A. Forge, N. Ingham, 2014, Stem Cell Research & Therapy.

Gender Differences in Myogenic Regulation along the Vascular Tree of the Gerbil Cochlea

W. Wier, P. Wangemann, K. Reimann, 2011, PloS one.

The Na+/H+ exchanger in transitional cells of the inner ear

P. Wangemann, D. C. Marcus, N. Shiga, 1993, Hearing Research.

Vestibular Dark Cells Contain an H+/Monocarboxylate− Cotransporter in Their Apical and Basolateral Membrane

P. Wangemann, J. Liu, M. Scofield, 1998, The Journal of Membrane Biology.

Functional evidence for a monocarboxylate transporter (MCT) in strial marginal cells and molecular evidence for MCT1 and MCT2 in stria vascularis

P. Wangemann, M. Scofield, M. Shimozono, 1997, Hearing Research.

β1-Adrenergic Receptors but not β2-Adrenergic or Vasopressin Receptors Regulate K+ Secretion in Vestibular Dark Cells of the Inner Ear

P. Wangemann, J. Liu, M. Scofield, 1999, The Journal of Membrane Biology.

Functional β2-Adrenergic Receptors Are Present in Nonstrial Tissues of the Lateral Wall in the Gerbil Cochlea

P. Wangemann, S. Schimanski, M. Scofield, 2001, Audiology and Neurotology.

K+ Secretion in Strial Marginal Cells is Stimulated via β1-Adrenergic Receptors but not via β2-Adrenergic or Vasopressin Receptors

P. Wangemann, S. Schimanski, J. Liu, 2000, The Journal of Membrane Biology.

ETA receptors in the gerbil spiral modiolar artery.

P. Wangemann, E. Scherer, 2002, Advances in oto-rhino-laryngology.

How Do Loop Diuretics Act?

P. Wangemann, R. Greger, A. Stefano, 2012, Drugs.

K+-induced swelling of vestibular dark cells is dependent on Na+ and Cl− and inhibited by piretanide

P. Wangemann, D. C. Marcus, 1990, Pflügers Archiv.

Cl−-channel blockers in the thick ascending limb of the loop of Henle Structure activity relationship

P. Wangemann, R. Greger, E. Schlatter, 2004, Pflügers Archiv.

Analogues of torasemide — structure function relationships —experiments in the thick ascending limb of the loop of Henle of rabbit nephron

P. Wangemann, J. Liégeois, R. Greger, 2004, Pflügers Archiv.

Expression of epithelial calcium transport system in rat cochlea and vestibular labyrinth

P. Wangemann, Donald G. Harbidge, Ruchira Singh, 2010, BMC Physiology.

Pharmacological reversal of endothelin-1 mediated constriction of the spiral modiolar artery: a potential new treatment for sudden sensorineural hearing loss

P. Wangemann, W. Arnold, E. Scherer, 2005, BMC ear, nose, and throat disorders.

Inner Ear Defects Induced by Null Mutationof the isk Gene

S. Heinemann, M. Lazdunski, K. Mclaughlin, 1996, Neuron.

I(sK) Channel in Strial Marginal Cells. Voltage-Dependence, Ion-Selectivity, Inhibition by 293B and Sensitivity to Clofilium.

P. Wangemann, D. C. Marcus, H. Sunose, 1997, Auditory neuroscience.

K+-induced stimulation of K+ secretion involves activation of the IsK channel in vestibular dark cells

P. Wangemann, Zhijun Shen, Jianzhong Liu, 1996, Hearing Research.

Cell volume control in vestibular dark cells during and after a hyposmotic challenge.

P. Wangemann, N. Shiga, 1994, The American journal of physiology.

Transepithelial voltage and resistance of vestibular dark cell epithelium from the gerbil ampulla

P. Wangemann, D. C. Marcus, Jianzhong Liu, 1994, Hearing Research.

DIDS increases K+ secretion through an IsKchannel in apical membrane of vestibular dark cell epithelium of gerbil

P. Wangemann, D. C. Marcus, N. Shiga, 1995, The Journal of Membrane Biology.

K+ Cycling and Its Regulation in the Cochlea and the Vestibular Labyrinth

P. Wangemann, 2002, Audiology and Neurotology.

Membrane potential measurements of transitional cells from the crista ampullaris of the Gerbil

P. Wangemann, D. C. Marcus, 1989, Pflügers Archiv.

Vestibular dark cells contain the Na + H + exchanger NHE-1 in

P. Wangemann, N. Shiga, Jianzhong Liu, 1996, Hearing Research.

Endothelin-1–Induced Vasospasms of Spiral Modiolar Artery Are Mediated by Rho-Kinase–Induced Ca2+ Sensitization of Contractile Apparatus and Reversed by Calcitonin Gene–Related Peptide

P. Wangemann, E. Scherer, M. Herzog, 2002 .

Endothelin-1–Induced Vasospasms of Spiral Modiolar Artery Are Mediated by Rho-Kinase–Induced Ca Sensitization of Contractile Apparatus and Reversed by Calcitonin Gene–Related Peptide

P. Wangemann, E. Scherer, 2002 .

Endothelin-1-induced vasospasms of spiral modiolar artery are mediated by rho-kinase-induced Ca(2+) sensitization of contractile apparatus and reversed by calcitonin gene-related Peptide.

P. Wangemann, E. Scherer, M. Herzog, 2002, Stroke.

' s response to reviews Pharmacological reversal of endothelin-1 mediated constriction of the spiral modiolar artery : a Title : potential new treatment for sudden sensorineural hearing loss

H. Shimokawa, P. Wangemann, E. Scherer, 2005 .

Chemical synthesis of tetracyclic terpenes and evaluation of antagonistic activity on endothelin-A receptors and voltage-gated calcium channels.

B. Zou, P. Wangemann, Aibin Shi, 2015, Bioorganic & medicinal chemistry.

Differential Desensitization of Ca2+ Mobilization and Vasoconstriction by ETA Receptors in the Gerbil Spiral Modiolar Artery

P. Wangemann, E. Scherer, K. Wonneberger, 2001, The Journal of Membrane Biology.

Ba2+ and amiloride uncover or induce a pH-sensitive and a Na+ or non-selective cation conductance in transitional cells of the inner ear

P. Wangemann, N. Shiga, 1994, Pflügers Archiv.

Claudin expression during early postnatal development of the murine cochlea

P. Wangemann, D. C. Marcus, T. Kudo, 2018, BMC Physiology.

CALL Methods in cell physiology Microarray-based comparison of three ampliﬁcation methods for nanogram amounts of total RNA

P. Wangemann, Glenn Deng, J. Heath, 2005 .

Osmotic water permeability of capillaries from the isolated spiral ligament: new in-vitro techniques for the study of vascular permeability and diameter

P. Wangemann, Jianzhong Liu, 1996, Hearing Research.

Two types of chloride channel in the basolateral membrane of vestibular dark cells

P. Wangemann, D. C. Marcus, S. Takeuchi, 1993, Hearing Research.

Endothelin-A receptors mediate vasoconstriction of capillaries in the spiral ligament

P. Wangemann, Jianzhong Liu, M. Sadanaga, 1997, Hearing Research.

Cochlear Homeostasis and Homeostatic Disorders

Philine Wangemann, P. Wangemann, 2008 .

Chloride secretion by semicircular canal duct epithelium is stimulated via beta 2-adrenergic receptors.

P. Wangemann, P. Milhaud, J. Lee, 2002, American journal of physiology. Cell physiology.

Targeted Ablation of Connexin26 in the Inner Ear Epithelial Gap Junction Network Causes Hearing Impairment and Cell Death

K. Willecke, M. Cohen-Salmon, C. Petit, 2002, Current Biology.

Cochlear and Vestibular Function and Dysfunction

P. Wangemann, D. C. Marcus, 2009 .

Localization of β1-Adrenergic Receptors in the Cochlea and the Vestibular Labyrinth

P. Wangemann, S. Schimanski, C. Fauser, 2004, The Journal of Membrane Biology.

Comparison of ion transport mechanisms between vestibular dark cells and strial marginal cells

P. Wangemann, 1995, Hearing Research.

Aminoglycoside antibiotics inhibit maxi-K+ channel in single isolated cochlear efferent nerve terminals

P. Wangemann, S. Takeuchi, 1993, Hearing Research.

N-Ethylmaleimide Stimulates and Inhibits Ion Transport in Vestibular Dark Cells of Gerbil.

P. Wangemann, D. C. Marcus, N. Shiga, 1994, Auditory neuroscience.

Blockers of Active Transport in the Thick Ascending Limb of the Loop of Henle

P. Wangemann, R. Greger, H. Lang, 1987 .

Slc26a4-insufficiency causes fluctuating hearing loss and stria vascularis dysfunction

A. Griffith, B. Choi, P. Wangemann, 2014, Neurobiology of Disease.

Mutations of KCNJ10 together with mutations of SLC26A4 cause digenic nonsyndromic hearing loss associated with enlarged vestibular aqueduct syndrome.

P. Wangemann, P. Snyder, Richard J. H. Smith, 2009, American journal of human genetics.

Mutations of KCNJ 10 Together with Mutations of SLC 26 A 4 Cause Digenic Nonsyndromic Hearing Loss Associated with Enlarged Vestibular Aqueduct Syndrome

T. Yang, P. Wangemann, P. Snyder, 2009 .

Supporting sensory transduction: cochlear fluid homeostasis and the endocochlear potential

Philine Wangemann, P. Wangemann, 2006, The Journal of physiology.

Molecular architecture underlying fluid absorption by the developing inner ear

Michael C. Kelly, A. Griffith, M. Kelley, 2017, eLife.

K+ cycling and the endocochlear potential

Philine Wangemann, P. Wangemann, 2002, Hearing Research.

Differential effects of ADH on sodium, chloride, potassium, calcium and magnesium transport in cortical and medullary thick ascending limbs of mouse nephron

P. Wangemann, N. Roinel, C. Bailly, 1988, Pflügers Archiv.

The diuretic effect of muzolimine

P. Wangemann, R. Greger, R. Braitsch, 1987, Pflügers Archiv.

CGRP Receptors in the Gerbil Spiral Modiolar Artery Mediate a Sustained Vasodilation via a Transient cAMP-mediated Ca2+-decrease

P. Wangemann, B. Rorabaugh, E. Scherer, 2002, The Journal of Membrane Biology.

Microarray-based comparison of three amplification methods for nanogram amounts of total RNA.

P. Wangemann, Glenn Deng, J. Heath, 2005, American journal of physiology. Cell physiology.

Tumor Necrosis Factor-&agr; Enhances Microvascular Tone and Reduces Blood Flow in the Cochlea via Enhanced Sphingosine-1-Phosphate Signaling

W. Wier, P. Wangemann, D. Lidington, 2010, Stroke.

Ca2+-activated nonselective cation, maxi K+ and Cl− channels in apical membrane of marginal cells of stria vascularis

P. Wangemann, D. C. Marcus, S. Takeuchi, 1992, Hearing Research.

Hypo-osmotic challenge stimulates transepithelial k+ secretion and activates apical isK channel in vestibular dark cells

P. Wangemann, A. Shipley, D. C. Marcus, 1995, The Journal of Membrane Biology.

The pH-sensitivity of transepithelial K+ transport in vestibular dark cells

P. Wangemann, N. Shiga, J. Liu, 1995, The Journal of Membrane Biology.

Evidence for the involvement of a K+ channel in isosmotic cell shrinking in vestibular dark cells.

P. Wangemann, D. C. Marcus, N. Shiga, 1992, The American journal of physiology.

Maxi K+ channel in apical membrane of vestibular dark cells.

P. Wangemann, D. C. Marcus, S. Takeuchi, 1992, The American journal of physiology.

Ca(2+)-activated nonselective cation channel in apical membrane of vestibular dark cells.

P. Wangemann, D. C. Marcus, S. Takeuchi, 1992, The American journal of physiology.

Slc26a7 Chloride Channel Activity and Localization in Mouse Reissner’s Membrane Epithelium

Daniel C. Marcus, Jie Xu, Philine Wangemann, 2014, PloS one.

Apical membrane P2Y4 purinergic receptor controls K+ secretion by strial marginal cell epithelium

P. Wangemann, J. Lee, D. C. Marcus, 2005, Cell Communication and Signaling.

Non-linear classification for on-the-fly fractional mass filtering and targeted precursor fragmentation in mass spectrometry experiments

Hanno Steen, Marc Kirchner, Wiebke Timm, 2010, Bioinform..

BIOINFORMATICS Non-linear classiﬁcation for on-the-ﬂy fractional mass ﬁltering and targeted precursor fragmentation in mass spectrometry experiments

H. Steen, Marc Kirchner, P. Wangemann, 2010 .

Muscarinic Receptors Control K+ Secretion in Inner Ear Strial Marginal Cells

P. Wangemann, E. Scherer, J. Liu, 2001, The Journal of Membrane Biology.

Ca2+-dependence and nifedipine-sensitivity of vascular tone and contractility in the isolated superfused spiral modiolar artery in vitro

P. Wangemann, M. Gratton, E. Cohn, 1998, Hearing Research.

Neurogenic regulation of cochlear blood flow occurs along the basilar artery, the anterior inferior cerebellar artery and at branch points of the spiral modiolar artery

Philine Wangemann, P. Wangemann, Kai Wonneberger, 2005, Hearing Research.

NOS Inhibition Enhances Myogenic Tone by Increasing Rho-Kinase Mediated Ca2+ Sensitivity in the Male but Not the Female Gerbil Spiral Modiolar Artery

P. Wangemann, K. Reimann, G. Krishnamoorthy, 2013, PloS one.

Tmc2 expression partially restores auditory function in a mouse model of DFNB7/B11 deafness caused by loss of Tmc1 function

J. R. Holt, H. Nakanishi, A. Griffith, 2018, Scientific Reports.

Loop diuretics.

P. Wangemann, R. Greger, 1987, Renal physiology.

Macrophage invasion contributes to degeneration of stria vascularis in Pendred syndrome mouse model

E. Green, P. Wangemann, S. Fleming, 2007 .

Loss of KCNJ 10 protein expression abolishes endocochlear potential and causes deafness in Pendred syndrome mouse model

E. Green, P. Wangemann, Tao Wu, 2022 .

Macrophage Invasion Contributes to Degeneration of Stria Vascularis in Pendred Syndrome Mouse Model Bmc Medicine Macrophage Invasion Contributes to Degeneration of Stria Vascularis in Pendred Syndrome Mouse Model

Edu, E. Green, P. Wangemann, 2022 .

Potassium ion movement in the inner ear: insights from genetic disease and mouse models.

P. Wangemann, T. Jentsch, A. Zdebik, 2009, Physiology.

Bmc Ear, Nose and Throat Disorders Open Access Pharmacological Reversal of Endothelin-1 Mediated Constriction of the Spiral Modiolar Artery: a Potential New Treatment for Sudden Sensorineural Hearing Loss

P. Wangemann, W. Arnold, E. Scherer, 2005 .

Non-linear classification for on-the-fly fractional mass filtering and targeted precursor fragmentation in mass spectrometry experiments

H. Steen, Marc Kirchner, P. Wangemann, 2010, Bioinform..

Tmc2 expression partially restores auditory function in a mouse model of DFNB7/B11 deafness caused by loss of Tmc1 function

J. R. Holt, H. Nakanishi, A. Griffith, 2018, Scientific Reports.

P2RX2 and P2RX4 receptors mediate cation absorption in transitional cells and supporting cells of the utricular macula

P. Wangemann, J. Choi, D. C. Marcus, 2019, Hearing Research.

Macrophage invasion contributes to degeneration of stria vascularis in Pendred syndrome mouse model

E. Green, P. Wangemann, S. Fleming, 2006, BMC medicine.

The Role of Pendrin in the Development of the Murine Inner Ear

P. Wangemann, 2011, Cellular Physiology and Biochemistry.