S. Narula

发表

In vivo characterization of interleukin‐4 as a potential wound healing agent

L. Broemeling, L. Phillips, M. Robson, 1995, Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society.

Structural characterization of nitric oxide synthase isoforms reveals striking active-site conservation

P. Weber, T. Fischmann, S. Narula, 1999, Nature Structural Biology.

treated alloreactive T cells that do not induce graft-versus-host disease - β cycle progression in interleukin 10 and transforming growth factor- Altered T-cell receptor?+?CD28-mediated signaling and blocked cell

V. Boussiotis, A. Berezovskaya, M. Roncarolo, 2013 .

Altered T-cell receptor + CD28-mediated signaling and blocked cell cycle progression in interleukin 10 and transforming growth factor-beta-treated alloreactive T cells that do not induce graft-versus-host disease.

V. Boussiotis, A. Berezovskaya, M. Roncarolo, 2001, Blood.

Interleukin 4 retards dissemination of a human B-cell lymphoma in severe combined immunodeficient mice.

S. Narula, L. Sullivan, J. Fine, 1995, Cancer research.

Cutting edge: species specificity of the CC chemokine 6Ckine signaling through the CXC chemokine receptor CXCR3: human 6Ckine is not a ligand for the human or mouse CXCR3 receptors.

S. Narula, H. Byrnes, H. Kaminski, 1999, Journal of immunology.

Endocannabinoid 2-arachidonyl glycerol is a full agonist through human type 2 cannabinoid receptor: antagonism by anandamide.

S. Narula, C. Lunn, D. Lundell, 2000, Molecular pharmacology.

Triaryl bis-sulfones as a new class of cannabinoid CB2 receptor inhibitors: identification of a lead and initial SAR studies.

S. Narula, C. Lunn, D. Lundell, 2005, Bioorganic & medicinal chemistry letters.

Viral interleukin 10 (IL-10), the human herpes virus 4 cellular IL-10 homologue, induces local anergy to allogeneic and syngeneic tumors

M. Lotze, P. Robbins, S. Narula, 1995, The Journal of experimental medicine.

Blocking ion channel KCNN4 alleviates the symptoms of experimental autoimmune encephalomyelitis in mice

A. Nomeir, S. Narula, A. Golovko, 2005, European journal of immunology.

Suppression of glomerulonephritis in lupus-prone NZB × NZW mice by RN486, a selective inhibitor of Bruton's tyrosine kinase.

Daigen Xu, H. Hilton, J. Demartino, 2013, Arthritis and rheumatism.

Characterization of a novel CRAC inhibitor that potently blocks human T cell activation and effector functions.

H. Bitter, P. Ravindran, J. Allard, 2013, Molecular immunology.

Btk inhibition suppresses agonist-induced human macrophage activation and inflammatory gene expression in RA synovial tissue explants

P. Tak, J. Demartino, S. Narula, 2014, Annals of the rheumatic diseases.

Aberrant in Vivo T Helper Type 2 Cell Response and Impaired Eosinophil Recruitment in Cc Chemokine Receptor 8 Knockout Mice

Tong-Yuan Yang, S. Lira, M. Napolitano, 2001, The Journal of experimental medicine.

Inhibition of fucosyltransferase VII by gallic acid and its derivatives.

S. Narula, D. Lundell, P. Ting, 2004, Archives of biochemistry and biophysics.

Human interferon-inducible 10-kDa protein and human interferon-inducible T cell alpha chemoattractant are allotopic ligands for human CXCR3: differential binding to receptor states.

S. Narula, J. Fine, P. Zavodny, 2001, Molecular pharmacology.

IL-10 and TGF-beta induce alloreactive CD4+CD25- T cells to acquire regulatory cell function.

M. Roncarolo, S. Narula, W. Murphy, 2003, Blood.

Characterization of interleukin-10 receptor expression on B-cell chronic lymphocytic leukemia cells.

M. Caligiuri, L. Blumenson, S. Narula, 1997, Blood.

Lymphomagenesis in the SCID-hu mouse involves abundant production of human interleukin-10.

M. Ross, J. Sklar, M. Monne, 1995, Blood.

Transgenic Expression of the Chemokine Receptor Encoded by Human Herpesvirus 8 Induces an Angioproliferative Disease Resembling Kaposi's Sarcoma

Tong-Yuan Yang, M. Leach, S. Lira, 2000, The Journal of experimental medicine.

Differential effects of exogenous interleukin-10 on cardiac allograft survival: inhibition of rejection by recipient pretreatment reflects impaired host accessory cell function.

J. Fung, L. Lu, A. Thomson, 1999, Transplantation.

Purification of ADAM 10 from bovine spleen as a TNFα convertase

S. Narula, C. Lunn, D. Lundell, 1997 .

Effect of Sch 55700, a Humanized Monoclonal Antibody to Human Interleukin-5, on Eosinophilic Responses and Bronchial Hyperreactivity

R. Egan, J. Emtage, S. Narula, 1999, Arzneimittelforschung.

An active covalently linked dimer of human interferon-gamma. Subunit orientation in the native protein.

S. Narula, C. Lunn, D. Lundell, 1992, The Journal of biological chemistry.

Crystal structure of a complex between interferon-gamma and its soluble high-affinity receptor.

W. Windsor, S. Narula, C. Lunn, 1995, Nature.

Inhibition of the development of collagen-induced arthritis in rhesus monkeys by a small molecular weight antagonist of CCR5.

S. Narula, E. Remarque, B. Hart, 2005, Arthritis and rheumatism.

Growth and expansion of human T regulatory type 1 cells are independent from TCR activation but require exogenous cytokines

M. Roncarolo, M. Levings, S. Narula, 2002, European journal of immunology.

Premature Death Inflammation , Runting , Infertility , and IL-23 Subunit p 19 Induces Multiorgan Ubiquitous Transgenic Expression of the Satwant Narula

M. Leach, R. Kastelein, J. Bazan, 2001 .

Inhibition of IRF5 cellular activity with cell-penetrating peptides that target homodimerization

Charles A. Wartchow, N. Fotouhi, Seng-Lai Tan, 2020, Science Advances.

An inhibitor of CD28-CD80 interactions impairs CD28-mediated costimulation of human CD4 T cells.

S. Narula, J. Fine, P. Zavodny, 1999, Cellular immunology.

Regulated Secretion of MuGM-CSF in Saccharomyces cerevisiae via GAL1:MFα1 Prepro Sequences

S. Narula, B. Frommer, P. Leibowitz, 1988 .

IL‐4 induces neutrophilic maturation of HL‐60 cells and activation of human peripheral blood neutrophils

S. Narula, L. Sullivan, L. Bober, 1995, Clinical and experimental immunology.

Structure and humanization of a rat monoclonal Fab to human interleukin-5.

W. Cook, S. Narula, N. Murgolo, 1996, Protein engineering.

Molecular cloning and expression of cardiac-specific myosin heavy chain gene sequences in chick embryo.

H. Arnold, S. Narula, M. Siddiqui, 1982, Journal of molecular biology.

Stimulation of Cytolytic Activity by Interleukin‐10

S. Narula, L. Sullivan, L. Hamilton, 1994, Journal of immunotherapy with emphasis on tumor immunology : official journal of the Society for Biological Therapy.

Purification of ADAM 10 from bovine spleen as a TNFalpha convertase.

S. Narula, C. Lunn, D. Lundell, 1997, FEBS letters.

Bruton's Tyrosine Kinase mediates platelet receptor-induced generation of microparticles: a potential mechanism for amplification of inflammatory responses in rheumatoid arthritis synovial joints.

Seng-Lai Tan, J. Demartino, S. Narula, 2013, Immunology letters.

Characterization of Recombinant Extracellular Domain of Human Interleukin-10 Receptor (*)

S. Narula, H. Rong, Edward Dolphin, 1995, The Journal of Biological Chemistry.

Development of a CD28 receptor binding-based screen and identification of a biologically active inhibitor.

S. Narula, V. Hegde, P. Zavodny, 1998, Analytical biochemistry.

Endogenous mouse interleukin-10 is up-regulated by exogenously administered recombinant human interleukin-10, but does not contribute to the efficacy of the human protein in mouse models of endotoxemia.

S. Narula, G. Denhardt, D. Manfra, 1999, Immunopharmacology.

Recipient pretreatment with mammalian IL-10 prolongs mouse cardiac allograft survival by inhibition of anti-donor T cell responses.

J. Fung, L. Lu, A. Thomson, 1999, Transplantation proceedings.

Systemic administration of anti-interleukin-10 antibody prolongs organ allograft survival in normal and presensitized recipients.

J. Fung, L. Lu, A. Thomson, 1998, Transplantation.

Suppression of the allogeneic response by human IL-10: a critical role for suppression of a synergy between IL-2 and TNF-alpha.

S. Narula, L. Sullivan, W. Tadmori, 1994, Cytokine.

Cytoplasmic and periplasmic expression of a highly basic protein, human interleukin 4, inEscherichia coli

R. Kastelein, S. Narula, J. Fossetta, 1990, Journal of Industrial Microbiology.

Characterization and differential expression of human vascular smooth muscle myosin light chain 2 isoform in nonmuscle cells.

C. Kumar, S. Narula, P. Leibowitz, 1989, Biochemistry.

Alterations of the amino terminus of murine interferon-γ: expression and biological activity

S. Narula, P. Leibowitz, P. Zavodny, 1988 .

Characterization of Peripheral Human Cannabinoid Receptor (hCB2) Expression and Pharmacology Using a Novel Radioligand, [35S]Sch225336*

S. Narula, J. Jackson, Shu-Cheng Chen, 2006, Journal of Biological Chemistry.

Human B cell-attracting chemokine 1 (BCA-1; CXCL13) is an agonist for the human CXCR3 receptor.

S. Narula, P. Zavodny, C. Chou, 2001, Cytokine.

A novel cannabinoid CB 2 receptor-selective inverse agonist blocks leukocyte recruitment in vivo

S. Narula, J. Jackson, C. Lunn, 2005 .

DIFFERENTIAL EFFECTS OF EXOGENOUS INTERLEUKIN-10 ON CARDIAC ALLOGRAFT SURVIVAL 1,2

T. Starzl, J. Fung, A. Thomson, 1999 .

Induction of CD 4 1 T Cell Alloantigen-Specific Hyporesponsiveness by IL-10 and TGF-b 1

F. Ruscetti, M. Roncarolo, S. Narula, 1999 .

Interleukin-10 dose-dependent regulation of CD4+ and CD8+ T cell-mediated graft-versus-host disease.

M. Roncarolo, S. Narula, B. Blazar, 1998, Transplantation.

This information is current as Mouse CXCR 3 Receptors 6 Ckine Is Not A Ligand for the Human or CXC Chemokine Receptor CXCR 3 : Human Chemokine 6 Ckine Signaling Through the Cutting Edge : Species Specificity of the CC

S. Narula, H. Byrnes, H. Kaminski, 1999 .

A highly sensitive and specific assay using a novel human growth hormone cDNA reporter gene regulated by the human interleukin-4 inducible germline ε transcript promoter

S. Narula, D. Lundell, P. Zavodny, 1998 .

A specific stimulator of granulocyte colony-stimulating factor accelerates recovery from cyclophosphamide-induced neutropenia in the mouse.

S. Narula, C. Gommoll, L. Hamilton, 1997, Blood.

Development of a Pharmacodynamic Assay Based on PLCγ2 Phosphorylation for Quantifying Spleen Tyrosine Kinase (SYK)–Bruton’s Tyrosine Kinase (BTK) Signaling

Seng-Lai Tan, J. Demartino, C. Kitson, 2013, Journal of biomolecular screening.

Importance of the loop connecting A and B helices of human interferon-gamma in recognition by interferon-gamma receptor.

M. Senior, S. Narula, C. Lunn, 1994, The Journal of biological chemistry.

A point mutation of human interferon γ abolishes receptor recognition

W. Windsor, S. Narula, N. Murgolo, 1992 .

Ubiquitous Transgenic Expression of the IL-23 Subunit p19 Induces Multiorgan Inflammation, Runting, Infertility, and Premature Death

M. Leach, R. Kastelein, S. Lira, 2001, The Journal of Immunology.

The effects of colony stimulating factors on human monocyte cell function.

S. Narula, L. Sullivan, M. Grace, 1995, International journal of immunopharmacology.

Interleukin-17 promotes angiogenesis and tumor growth.

M. Lotze, P. Robbins, M. Ono, 2003, Blood.

CCR6 mediates dendritic cell localization, lymphocyte homeostasis, and immune responses in mucosal tissue.

H. Greenberg, S. Lira, S. Narula, 2000, Immunity.

Exploiting the cell membrane for the production of heterologous proteins in Escherichia coli

R. Kastelein, S. Narula, J. Fossetta, 1990, Biotechnology and applied biochemistry.

New Cytokines as Potential Drugs

R. Coffman, S. Narula, 2000, Progress in Inflammation Research.

The effect of GM-CSF and G-CSF on human neutrophil function.

S. Narula, L. Sullivan, M. Grace, 1995, Immunopharmacology.

Cloning and characterization of a vertebrate cellular myosin regulatory light chain complementary DNA.

C. Kumar, S. Narula, P. Leibowitz, 1990, Circulation research.

Interferon-α gene therapy for cancer: retroviral transduction of fibroblasts and particle-mediated transfection of tumor cells are both effective strategies for gene delivery in murine tumor models

A. Gambotto, S. Narula, T. Tüting, 1997, Gene Therapy.

TL1A/TNFSF15 directly induces proinflammatory cytokines, including TNFα, from CD3+CD161+ T cells to exacerbate gut inflammation

N. Beaucamp, A. Fanning, F. Shanahan, 2012, Mucosal Immunology.

The functional characterization of interleukin-10 receptor expression on human natural killer cells.

R. Baiocchi, S. Narula, W. Carson, 1995, Blood.

Signaling by Covalent Heterodimers of Interferon-γ

S. Pestka, S. Kotenko, S. Narula, 2000, The Journal of Biological Chemistry.

Regulatory effects of interleukin-4 and interleukin-10 on human neutrophil function ex vivo and on neutrophil influx in a rat model of arthritis.

M. Leach, S. Narula, J. Jackson, 2000, Arthritis and rheumatism.

Expression of biologically active, mature human granulocyte-macrophage colony stimulating factor with anE. coli secretory expression system

R. Kastelein, S. Narula, B. Frommer, 1988, Current Microbiology.

Induction of CD4+ T cell alloantigen-specific hyporesponsiveness by IL-10 and TGF-beta.

F. Ruscetti, M. Roncarolo, S. Narula, 1999, Journal of immunology.

Type 1 T regulatory cells

M. Roncarolo, M. Levings, S. Narula, 2001, Immunological reviews.

Structural elements required for receptor recognition of human interferon-gamma.

S. Narula, D. Lundell, 1994, Pharmacology & therapeutics.

Systemic administration of cellular IL-10 induces an effective, specific, and long-lived immune response against established tumors in mice.

M. Lotze, P. Robbins, S. Narula, 1996, Journal of immunology.

Selective inhibition of spleen tyrosine kinase (SYK) with a novel orally bioavailable small molecule inhibitor, RO9021, impinges on various innate and adaptive immune responses: implications for SYK inhibitors in autoimmune disease therapy

Johannes C. Hermann, C. Lukacs, Seng-Lai Tan, 2013, Arthritis Research & Therapy.

Natural regulatory T cells are resistant to calcium release-activated calcium (CRAC/ORAI) channel inhibition.

J. Allard, J. Demartino, C. Kitson, 2013, International immunology.

RN486, a Selective Bruton's Tyrosine Kinase Inhibitor, Abrogates Immune Hypersensitivity Responses and Arthritis in Rodents

Daigen Xu, J. Demartino, S. Narula, 2012, Journal of Pharmacology and Experimental Therapeutics.

Crystal structure of a complex between interferon-γ and its soluble high-affinity receptor

W. Windsor, S. Narula, C. Lunn, 1995, Nature.

Characterization of interleukin-10 receptors on human and mouse cells.

S. Narula, C C Chou, S K Narula, 1993, The Journal of biological chemistry.

A Novel Cannabinoid Peripheral Cannabinoid Receptor-Selective Inverse Agonist Blocks Leukocyte Recruitment in Vivo

Jay S. Fine, S. Narula, J. Jackson, 2006, Journal of Pharmacology and Experimental Therapeutics.

The carboxyl-terminal region of human interferon gamma is important for biological activity: mutagenic and NMR analysis.

S. Narula, J. Fossetta, C. Lunn, 1991, Protein engineering.

The pyrimidinergic P2Y6 receptor mediates a novel release of proinflammatory cytokines and chemokines in monocytic cells stimulated with UDP.

S. Narula, B. Wilburn, Kyle Palmer, 2005, Biochemical and biophysical research communications.

The nucleotide sequence of chicken smooth muscle myosin light chain two.

C. Kumar, S. Narula, P. Leibowitz, 1988, Nucleic acids research.

Thymic stromal lymphopoietin receptor blockade reduces allergic inflammation in a cynomolgus monkey model of asthma.

Donavan T. Cheng, S. Apparsundaram, H. Bitter, 2013, The Journal of allergy and clinical immunology.

Regulation of granulocyte colony-stimulating factor gene expression by interleukin-17.

S. Narula, C. Gommoll, J. Fine, 1998, Immunology letters.

JPET #187740 RN486 [6-Cyclopropyl-8-fluoro-2-(2-hydroxymethyl-3-{1-methyl-5-[5-(4-methyl- piperazin-1-yl)-pyridin-2-ylamino]-6-oxo-1,6-dihydro-pyridin-3-yl}-phenyl)-2H- isoquinolin-1-one], a Selective Bruton’s Tyrosine Kinase (Btk) Inhibitor, Abrogates Immune Hypersensitivity Responses and Arthritis

Daigen Xu, J. Demartino, S. Narula, 2011 .

Characterization of potential antagonists of human interleukin 5 demonstrates their cross-reactivity with receptors for interleukin 3 and granulocyte-macrophage colony-stimulating factor.

S. Narula, D. Lundell, C C Chou, 1997, European journal of biochemistry.

A point mutation of human interferon gamma abolishes receptor recognition.

W. Windsor, S. Narula, N. Murgolo, 1992, Protein Engineering.

Interleukin-10 eliminates anti-CD3 monoclonal antibody-induced mortality and prolongs heart allograft survival in inbred mice.

S. Narula, C. Larsen, D. Alexander, 1995, Transplantation proceedings.

Interleukin‐10 Suppresses the Development of Collagen Type II‐Induced Arthritis and Ameliorates Sustained Arthritis in Rats

R. Holmdahl, S. Narula, A. O’Garra, 1996, Scandinavian journal of immunology.

Immunomodulation of Crohn's disease by interleukin-10.

S. Narula, P. Grint, D. Cutler, 1998, Agents and actions. Supplements.

Aberrant in Vivo T Helper Type 2 Cell Response and Impaired Eosinophil Recruitment in Cc Chemokine Receptor 8 Knockout Mice

S. Lira, M. Napolitano, S. Kunkel, 2001, The Journal of experimental medicine.

RN486, a Selective Bruton's Tyrosine Kinase Inhibitor, Abrogates Immune Hypersensitivity Responses and Arthritis in Rodents

Daigen Xu, S. Narula, D. Srinivasan, 2012, Journal of Pharmacology and Experimental Therapeutics.

Expression of human inducible nitric oxide synthase in Escherichia coli

S. Narula, X. Niu, J. Fossetta, 1996, FEBS letters.