H. Blackwell

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Nonwoven Polymer Nanofiber Coatings That Inhibit Quorum Sensing in Staphylococcus aureus: Toward New Nonbactericidal Approaches to Infection Control.

D. M. Lynn, M. Kratochvil, Tian Yang, 2017, ACS infectious diseases.

A one-bead, one-stock solution approach to chemical genetics: part 1.

John A. Tallarico, M. Foley, J. Tallarico, 2001, Chemistry & biology.

Small molecule inhibitors of bacterial quorum sensing and biofilm formation.

H. Blackwell, Grant D. Geske, Rachel J. Wezeman, 2005, Journal of the American Chemical Society.

Highly Efficient Synthesis of Covalently Cross-Linked Peptide Helices by Ring-Closing Metathesis.

Helen E Blackwell, R. Grubbs, H. Blackwell, 1998, Angewandte Chemie.

Efficient construction of diketopiperazine macroarrays through a cyclative-cleavage strategy and their evaluation as luminescence inhibitors in the bacterial symbiont Vibrio fischeri.

H. Blackwell, Jennifer Campbell, 2009, Journal of combinatorial chemistry.

Structure-function relationships in peptoids: recent advances toward deciphering the structural requirements for biological function.

Helen E Blackwell, H. Blackwell, Sarah A. Fowler, 2009, Organic & biomolecular chemistry.

Rapid synthesis of diketopiperazine macroarrays via Ugi four-component reactions on planar solid supports.

H. Blackwell, Q. Lin, 2006, Chemical communications.

Improved small-molecule macroarray platform for the rapid synthesis and discovery of antibacterial chalcones.

B. Weisblum, H. Blackwell, Matthew D. Bowman, 2011, ACS combinatorial science.

Identification of small molecules that strongly inhibit bacterial quorum sensing using a high-throughput lipid vesicle lysis assay

D. M. Lynn, H. Blackwell, Curran G. Gahan, 2021, Cell Chemical Biology.

Structure-Function Analyses of the N-Butanoyl l-Homoserine Lactone Quorum-Sensing Signal Define Features Critical to Activity in RhlR.

H. Blackwell, E. Brown, M. Boursier, 2018, ACS chemical biology.

Potent and Selective Modulation of the RhlR Quorum Sensing Receptor by Using Non‐native Ligands: An Emerging Target for Virulence Control in Pseudomonas aeruginosa

Margrith E. Mattmann, H. Blackwell, Joseph D. Moore, 2015, Chembiochem : a European journal of chemical biology.

A Comparative Analysis of Synthetic Quorum Sensing Modulators in Pseudomonas aeruginosa: New Insights into Mechanism, Active Efflux Susceptibility, Phenotypic Response, and Next-Generation Ligand Design

H. Blackwell, F. M. Rossi, K. Nyffeler, 2015, Journal of the American Chemical Society.

Identification of Synthetic Inducers and Inhibitors of the 3 Quorum-Sensing Regulator LasR in Pseudomonas aeruginosa 4 by High-Throughput Screening 5 6 7 8

J. Handelsman, H. Blackwell, Grant D. Geske, 2010 .

Small molecule macroarray construction via palladium-mediated carbon-carbon bond-forming reactions: highly efficient synthesis and screening of stilbene arrays.

H. Blackwell, R. Frei, Reto Frei, 2010, Chemistry.

Diversity‐Oriented Synthesis of Biaryl‐Containing Medium Rings Using a One Bead/One Stock Solution Platform.

S. Schreiber, D. Spring, H. Blackwell, 2002 .

Plant Responses to Bacterial N-Acyl l-Homoserine Lactones are Dependent on Enzymatic Degradation to l-Homoserine

Andrew G. Palmer, Jean-Michel Ané, H. Blackwell, 2014, ACS chemical biology.

Design, synthesis, and biochemical characterization of non-native antagonists of the Pseudomonas aeruginosa quorum sensing receptor LasR with nanomolar IC50 values.

H. Blackwell, Matthew C. O’Reilly, K. Nyffeler, 2020, ACS infectious diseases.

Design, synthesis, and biochemical characterization of non-native antagonists of the Pseudomonas aeruginosa quorum sensing receptor LasR with nanomolar IC 50 values

H. Blackwell, Matthew C. O’Reilly, K. Nyffeler, 2020 .

N-Acyl l-Homocysteine Thiolactones Are Potent and Stable Synthetic Modulators of the RhlR Quorum Sensing Receptor in Pseudomonas aeruginosa.

H. Blackwell, M. Boursier, Joshua B Combs, 2019, ACS chemical biology.

Selection of Appropriate Autoinducer Analogues for the Modulation of Quorum Sensing at the Host-Bacterium Interface.

Nidhi P. Mehta, Andrew G. Palmer, H. Blackwell, 2018, ACS chemical biology.

Structural and Biochemical Studies of Non-native Agonists of the LasR Quorum-Sensing Receptor Reveal an L3 Loop "Out" Conformation for LasR.

S. Nair, H. Blackwell, S. Dong, 2018, Cell chemical biology.

Identification of Synthetic Inducers and Inhibitors of the Quorum-Sensing Regulator LasR in Pseudomonas aeruginosa by High-Throughput Screening

J. Handelsman, H. Blackwell, Grant D. Geske, 2010, Applied and Environmental Microbiology.

Tuning peptoid secondary structure with pentafluoroaromatic functionality: a new design paradigm for the construction of discretely folded peptoid structures.

H. Blackwell, Benjamin C. Gorske, 2006, Journal of the American Chemical Society.

Local and tunable n-->pi* interactions regulate amide isomerism in the peptoid backbone.

H. Blackwell, Grant D. Geske, Benjamin C. Gorske, 2007, Journal of the American Chemical Society.

Surface Coatings that Promote Rapid Release of Peptide‐Based AgrC Inhibitors for Attenuation of Quorum Sensing in Staphylococcus aureus

D. M. Lynn, M. Kratochvil, H. Blackwell, 2014, Advanced healthcare materials.

Highly potent inhibitors of quorum sensing in Staphylococcus aureus revealed through a systematic synthetic study of the group-III autoinducing peptide.

H. Blackwell, D. Koenig, Yftah Tal‐Gan, 2013, Journal of the American Chemical Society.

Synthesis of the 17-electron cations [FeL(L′)(NO)2]+(L, L′= PPh3, OPPh3): structure and bonding in four-co-ordinate metal dinitrosyls, and implications for the identity of paramagnetic iron dinitrosyl complex catalysts

A. Orpen, H. Blackwell, J. Crossley, 1996 .

Application of Ring-Closing Metathesis to the Synthesis of Rigidified Amino Acids and Peptides.

Scott J. Miller, R. Grubbs, H. Blackwell, 1997 .

Deciphering a protolanguage for bacteria-host communication.

Andrew G. Palmer, H. Blackwell, 2008, Nature chemical biology.

Nanoporous Superhydrophobic Coatings that Promote the Extended Release of Water-Labile Quorum Sensing Inhibitors and Enable Long-Term Modulation of Quorum Sensing in Staphylococcus aureus

D. M. Lynn, M. Kratochvil, Tian Yang, 2015, ACS biomaterials science & engineering.

Control of Quorum Sensing by a Burkholderia pseudomallei Multidrug Efﬂux Pump (cid:1)

Margrith E. Mattmann, H. Blackwell, H. Suga, 2007 .

Chemical Genetics Reveals Environment-Specific Roles for Quorum Sensing Circuits in Pseudomonas aeruginosa.

H. Blackwell, Michael A. Welsh, 2016, Cell chemical biology.

New strategies for the design of folded peptoids revealed by a survey of noncovalent interactions in model systems.

H. Blackwell, Sarah A. Fowler, Joseph R. Stringer, 2009, Journal of the American Chemical Society.

Expedient synthesis and design strategies for new peptoid construction.

H. Blackwell, Emily J. Guerard, S. Jewell, 2005, Organic letters.

Chemical Interrogation of LuxR-type Quorum Sensing Receptors Reveals New Insights into Receptor Selectivity and the Potential for Interspecies Bacterial Signaling.

H. Blackwell, J. P. Gerdt, M. Boursier, 2017, ACS chemical biology.

Simplified Autoinducing Peptide Mimetics with Single-Nanomolar Activity Against the Staphylococcus aureus AgrC Quorum Sensing Receptor.

H. Blackwell, Joseph K. Vasquez, 2019, ACS infectious diseases.

Discovery of fluorescent cyanopyridine and deazalumazine dyes using small molecule macroarrays.

H. Blackwell, Matthew D. Bowman, Megan M. Jacobson, 2006, Organic letters.

Efficient synthesis of small molecule macroarrays: optimization of the macroarray synthesis platform and examination of microwave and conventional heating methods

H. Blackwell, Matthew D. Bowman, Megan M. Jacobson, 2006 .

Small Molecules with Either Receptor-Selective or Pan-Receptor Activity in the Three LuxR-Type Receptors that Regulate Quorum Sensing in Pseudomonas aeruginosa.

H. Blackwell, K. Nyffeler, Emma E. Santa, 2022, ACS chemical biology.

Non‐native N‐Aroyl L‐Homoserine Lactones Are Potent Modulators of the Quorum Sensing Receptor RpaR in Rhodopseudomonas palustris

H. Blackwell, Christine Mcinnis, 2014, Chembiochem : a European journal of chemical biology.

Interception of quorum sensing in Staphylococcus aureus: a new niche for peptidomimetics.

Helen E Blackwell, H. Blackwell, Benjamin C Gorske, 2006, Organic & biomolecular chemistry.

Out of the oil bath and into the oven--microwave-assisted combinatorial chemistry heats up.

Helen E Blackwell, H. Blackwell, 2003, Organic & biomolecular chemistry.

Hitting the SPOT: small-molecule macroarrays advance combinatorial synthesis.

Helen E Blackwell, H. Blackwell, 2006, Current opinion in chemical biology.

Microwave-accelerated SPOT-synthesis on cellulose supports.

Ryan C. Jeske, H. Blackwell, Matthew D. Bowman, 2004, Organic letters.

luorination of Alkyl Aryl Thioethers with Halonium Electrophiles in the Presence of Fluorinating Reagents and Its Application for 18F-Radiolabeling

H. Blackwell, E. Nakamura, I. Guzei, 2010 .

Small molecule macroarray construction via Ugi four-component reactions.

H. Blackwell, Q. Lin, Jennifer C. O'Neill, 2005, Organic letters.

Ring-closing metathesis of olefinic peptides: design, synthesis, and structural characterization of macrocyclic helical peptides.

R. Grubbs, H. Blackwell, R. Howard, 2001, The Journal of organic chemistry.

Introduction to bacterial signals and chemical communication.

C. Fuqua, H. Blackwell, 2011, Chemical reviews.

New Approaches to Olefin Cross-Metathesis

Robert H. Grubbs, Daniel J. O'Leary, Helen E. Blackwell, 2000 .

Terminal olefin cross-metathesis with acrolein acetals

R. Grubbs, H. Blackwell, R. Washenfelder, 1999 .

Novel methods for cross-metathesis of terminal olefins

R. Grubbs, H. Blackwell, D. J. O'Leary, 1998 .

Decoding Products of Diversity Pathways from Stock Solutions Derived from Single Polymeric Macrobeads

S. Schreiber, H. Blackwell, L. Pérez, 2001 .

A peptoid ribbon secondary structure.

H. Blackwell, I. Guzei, J. A. Crapster, 2013, Angewandte Chemie.

Extraordinarily robust polyproline type I peptoid helices generated via the incorporation of α-chiral aromatic N-1-naphthylethyl side chains.

Ilia A Guzei, Helen E Blackwell, H. Blackwell, 2011, Journal of the American Chemical Society.

Exploiting site-site interactions on solid support to generate dimeric molecules.

P. Clemons, S. Schreiber, H. Blackwell, 2001, Organic letters.

2-Aminobenzimidazole derivatives strongly inhibit and disperse Pseudomonas aeruginosa biofilms.

H. Blackwell, R. Frei, Anthony S. Breitbach, 2012, Angewandte Chemie.

Construction of peptoids with all trans-amide backbones and peptoid reverse turns via the tactical incorporation of N-aryl side chains capable of hydrogen bonding.

H. Blackwell, I. Guzei, Joseph R. Stringer, 2010, The Journal of organic chemistry.

Re-entrant isotropic phase in a supramolecular disc-like oligomer of 4-[3,4,5-tris(n-dodecanyloxy)benzoyloxy]-4′-[(2-vinyloxy)ethoxy]biphenyl

V. Percec, G. Ungar, H. Blackwell, 1992 .

Bacterial Quorum Sensing Signals Self-Assemble in Aqueous Media to Form Micelles and Vesicles: An Integrated Experimental and Molecular Dynamics Study.

N. Abbott, D. M. Lynn, H. Blackwell, 2020, The journal of physical chemistry. B.

N-Acyl homoserine lactone analog modulators of the Pseudomonas aeruginosa RhlI quorum sensing signal synthase.

H. Blackwell, H. Arthanari, E. Brown, 2019, ACS chemical biology.

Genetic mapping of microbial and host traits reveals production of immunomodulatory lipids by Akkermansia muciniphila in the murine gut

K. Broman, D. Gatti, K. Schueler, 2023, Nature Microbiology.

New and unexpected insights into the modulation of LuxR-type quorum sensing by cyclic dipeptides.

Jennifer Campbell, Helen E Blackwell, H. Blackwell, 2009, ACS chemical biology.

Control of Quorum Sensing by a Burkholderia pseudomallei Multidrug Efflux Pump

Margrith E. Mattmann, H. Blackwell, H. Suga, 2007, Journal of bacteriology.

Chemical Genetic Approaches to Plant Biology1

Yunde Zhao, H. Blackwell, 2003, Plant Physiology.

Synthesis and biological evaluation of triazole-containing N-acyl homoserine lactones as quorum sensing modulators.

T. Tolker-Nielsen, H. Blackwell, M. Givskov, 2013, Organic & biomolecular chemistry.

Non-native autoinducer analogs capable of modulating the SdiA quorum sensing receptor in Salmonella enterica serovar Typhimurium

H. Blackwell, M. Styles, 2018, Beilstein journal of organic chemistry.

Self-assembly of taper-shaped monoesters of oligo(ethylene oxide) with 3,4,5-tris(n-dodecan-1-yloxy)benzoic acid and of their polymethacrylates into tubular supramolecular architectures displaying a columnar hexagonal mesophase

V. Percec, G. Ungar, H. Blackwell, 1993 .

SIR1, an Upstream Component in Auxin Signaling Identified by Chemical Genetics

S. Schreiber, J. Chory, Yunde Zhao, 2003, Science.

Systems genetics uncovers microbe-lipid-host connections in the murine gut

H. Blackwell, F. Rey, G. Keele, 2021, bioRxiv.

Identification of a Class of Small Molecule Inhibitors of the Sirtuin Family of NAD-dependent Deacetylases by Phenotypic Screening*

S. Schreiber, D. Moazed, C. Grozinger, 2001, The Journal of Biological Chemistry.

Small molecule disruption of quorum sensing cross-regulation in pseudomonas aeruginosa causes major and unexpected alterations to virulence phenotypes.

H. Blackwell, Joseph D. Moore, N. Eibergen, 2015, Journal of the American Chemical Society.

Attenuation of quorum sensing in the pathogen Acinetobacter baumannii using non-native N-Acyl homoserine lactones.

P. Rather, H. Blackwell, Michael A. Welsh, 2012, ACS chemical biology.

N-phenylacetanoyl-L-homoserine lactones can strongly antagonize or superagonize quorum sensing in Vibrio fischeri.

H. Blackwell, Grant D. Geske, Jennifer C. O'Neill, 2007, ACS chemical biology.

Isovaleryl-homoserine lactone, an unusual branched-chain quorum-sensing signal from the soybean symbiont Bradyrhizobium japonicum

Helen E Blackwell, E. Greenberg, G. Pessi, 2011, Proceedings of the National Academy of Sciences.

Liquid Crystal-Infused Porous Polymer Surfaces: A "Slippery" Soft Material Platform for the Naked-Eye Detection and Discrimination of Amphiphilic Species.

D. M. Lynn, U. Manna, H. Blackwell, 2021, ACS applied materials & interfaces.

Liquid Crystal Emulsions that Intercept and Report on Bacterial Quorum Sensing.

N. Abbott, D. M. Lynn, H. Blackwell, 2020, ACS applied materials & interfaces.

Small molecules that modulate quorum sensing and control virulence in Pseudomonas aeruginosa.

Margrith E. Mattmann, H. Blackwell, 2010, The Journal of organic chemistry.

Expanding dialogues: from natural autoinducers to non-natural analogues that modulate quorum sensing in Gram-negative bacteria.

Helen E Blackwell, H. Blackwell, Grant D. Geske, 2008, Chemical Society reviews.

Modulation of bacterial quorum sensing with synthetic ligands: systematic evaluation of N-acylated homoserine lactones in multiple species and new insights into their mechanisms of action.

Helen E Blackwell, Margrith E. Mattmann, H. Blackwell, 2007, Journal of the American Chemical Society.

Active Efflux Influences the Potency of Quorum Sensing Inhibitors in Pseudomonas aeruginosa

H. Blackwell, J. P. Gerdt, Joseph D. Moore, 2014, Chembiochem : a European journal of chemical biology.

Competition Studies Confirm Two Major Barriers That Can Preclude the Spread of Resistance to Quorum-Sensing Inhibitors in Bacteria

H. Blackwell, J. P. Gerdt, 2014, ACS chemical biology.

Slippery Antifouling Polymer Coatings Fabricated Entirely from Biodegradable and Biocompatible Components.

D. M. Lynn, S. Palecek, H. Blackwell, 2022, ACS applied materials & interfaces.

Fabrication of Slippery Liquid-Infused Coatings in Flexible Narrow-Bore Tubing.

D. M. Lynn, H. Blackwell, H. Agarwal, 2021, ACS applied materials & interfaces.

Interactions of Bacterial Quorum Sensing Signals with Model Lipid Membranes: Influence of Membrane Composition on Membrane Remodeling.

D. M. Lynn, H. Blackwell, R. V. Van Lehn, 2022, Langmuir : the ACS journal of surfaces and colloids.

Interactions of Bacterial Quorum Sensing Signals with Model Lipid Membranes: Influence of Acyl Tail Structure on Multiscale Response.

D. M. Lynn, H. Blackwell, R. V. Van Lehn, 2021, Langmuir : the ACS journal of surfaces and colloids.

Bacterial Quorum Sensing Signals Promote Large-Scale Remodeling of Lipid Membranes.

D. M. Lynn, H. Blackwell, R. V. Van Lehn, 2021, Langmuir : the ACS journal of surfaces and colloids.

Diversity-oriented synthesis of biaryl-containing medium rings using a one bead/one stock solution platform.

Stuart L Schreiber, David R Spring, Helen E Blackwell, 2002, Journal of the American Chemical Society.

Structural characterization of native autoinducing peptides and abiotic analogues reveals key features essential for activation and inhibition of an AgrC quorum sensing receptor in Staphylococcus aureus.

Gabriel Cornilescu, H. Blackwell, C. Cornilescu, 2013, Journal of the American Chemical Society.

Potent and Selective Synthetic Modulators of a Quorum Sensing Repressor in Pseudomonas aeruginosa Identified from Second‐Generation Libraries of N‐Acylated L‐Homoserine Lactones

Margrith E. Mattmann, H. Blackwell, Patrick M. Shipway, 2011, Chembiochem : a European journal of chemical biology.

Microwave-Facilitated SPOT-Synthesis of Antibacterial Dipeptoids.

Stefan Bräse, Helen E Blackwell, Daniel Fritz, 2017, ACS combinatorial science.

Slippery Liquid‐Infused Porous Surfaces that Prevent Microbial Surface Fouling and Kill Non‐Adherent Pathogens in Surrounding Media: A Controlled Release Approach

Sean P. Palecek, D. M. Lynn, U. Manna, 2016, Advanced functional materials.

Evaluation of a focused library of N-aryl L-homoserine lactones reveals a new set of potent quorum sensing modulators.

Margrith E. Mattmann, H. Blackwell, Grant D. Geske, 2008, Bioorganic & medicinal chemistry letters.

Comparative Analyses of N‐Acylated Homoserine Lactones Reveal Unique Structural Features that Dictate Their Ability to Activate or Inhibit Quorum Sensing

Margrith E. Mattmann, H. Blackwell, Grant D. Geske, 2008, Chembiochem : a European journal of chemical biology.

Bacterial crowd control with iron.

H. Blackwell, 2005, Chemistry & biology.

Rapid identification of antibacterial agents effective against Staphylococcus aureus using small-molecule macroarrays.

H. Blackwell, Matthew D. Bowman, Joseph R. Stringer, 2007, Chemistry & biology.

Chemical and biomolecular insights into the Staphylococcus aureus agr quorum sensing system: Current progress and ongoing challenges.

Jordan T. York, H. Blackwell, Ke Zhao, 2023, Israel journal of chemistry.

Omics Technologies to Understand Activation of a Biosynthetic Gene Cluster in Micromonospora sp. WMMB235: Deciphering Keyicin Biosynthesis

Doug R. Braun, H. Blackwell, J. Kwan, 2019, ACS chemical biology.

Potent modulation of the CepR quorum sensing receptor and virulence in a Burkholderia cepacia complex member using non-native lactone ligands

Betty L. Slinger, H. Blackwell, Josephine R. Chandler, 2019, Scientific Reports.

Slippery Liquid-Infused Porous Surfaces that Prevent Bacterial Surface Fouling and Inhibit Virulence Phenotypes in Surrounding Planktonic Cells.

D. M. Lynn, U. Manna, M. Kratochvil, 2016, ACS infectious diseases.

Quorum-sensing signals in the microbial community of the cabbage white butterfly larval midgut

Courtney J. Robinson, J. Handelsman, H. Blackwell, 2008, The ISME Journal.

Efficient synthesis and evaluation of quorum-sensing modulators using small molecule macroarrays.

H. Blackwell, Grant D. Geske, Thanit Praneenararat, 2009, Organic letters.

Interkingdom Responses to Bacterial Quorum Sensing Signals Regulate Frequency and Rate of Nodulation in Legume–Rhizobia Symbiosis

Andrew G. Palmer, Jean-Michel Ané, H. Blackwell, 2016, ChemBioChem.

Chemical methods to interrogate bacterial quorum sensing pathways.

Andrew G. Palmer, H. Blackwell, Thanit Praneenararat, 2012, Organic & biomolecular chemistry.

Expedient construction of small molecule macroarrays via sequential palladium- and copper-mediated reactions and their ex situ biological testing.

H. Blackwell, R. Frei, Anthony S. Breitbach, 2012, Chemical science.

Attenuation of virulence in pathogenic bacteria using synthetic quorum-sensing modulators under native conditions on plant hosts.

Andrew G. Palmer, H. Blackwell, Evan Streng, 2011, ACS chemical biology.

Thiolactone modulators of quorum sensing revealed through library design and screening.

H. Blackwell, Christine Mcinnis, 2011, Bioorganic & medicinal chemistry.

Design, synthesis, and biological evaluation of abiotic, non-lactone modulators of LuxR-type quorum sensing.

H. Blackwell, Christine Mcinnis, 2011, Bioorganic & medicinal chemistry.

Quorum Sensing in Bacterial Species that Use Degenerate Autoinducers Can Be Tuned by Using Structurally Identical Non‐native Ligands

Andrew G. Palmer, H. Blackwell, K. Jewell, 2011, Chembiochem : a European journal of chemical biology.

A comparative study of non-native N-acyl l-homoserine lactone analogs in two Pseudomonas aeruginosa quorum sensing receptors that share a common native ligand yet inversely regulate virulence.

H. Blackwell, M. Boursier, Joshua B Combs, 2018, Bioorganic & medicinal chemistry.

Chemical probes of quorum sensing: from compound development to biological discovery.

H. Blackwell, Michael A. Welsh, 2016, FEMS microbiology reviews.

Synthetic ligands that activate and inhibit a quorum-sensing regulator in Pseudomonas aeruginosa.

E. Greenberg, Margrith E. Mattmann, H. Blackwell, 2008, Bioorganic & medicinal chemistry letters.

Identification of Unanticipated and Novel N-Acyl L-Homoserine Lactones (AHLs) Using a Sensitive Non-Targeted LC-MS/MS Method

H. Blackwell, D. Amador-Noguez, N. Patel, 2016, PloS one.

Mechanism of agonism and antagonism of the Pseudomonas aeruginosa quorum sensing regulator QscR with non‐native ligands

M. Churchill, H. Blackwell, K. Hansen, 2018, Molecular microbiology.

Autoinducer-fluorophore conjugates enable FRET in LuxR proteins in vitro and in cells

Betty L. Slinger, Margrith E. Mattmann, H. Blackwell, 2022, Nature Chemical Biology.

A New Model for Transitioning Students from the Undergraduate Teaching Laboratory to the Research Laboratory. The Evolution of an Intermediate Organic Synthesis Laboratory Course

H. Blackwell, Grant D. Geske, J. J. Hollenbeck, 2006 .

Slippery nanoemulsion-infused porous surfaces (SNIPS): anti-fouling coatings that can host and sustain the release of water-soluble agents.

D. M. Lynn, H. Blackwell, Harshita Agarwal, 2021, Chemical communications.

Chemical modification of reactive multilayered films fabricated from poly(2-alkenyl azlactone)s: design of surfaces that prevent or promote mammalian cell adhesion and bacterial biofilm growth.

M. E. Buck, D. M. Lynn, H. Blackwell, 2009, Biomacromolecules.

Unraveling the contributions of hydrogen-bonding interactions to the activity of native and non-native ligands in the quorum-sensing receptor LasR.

H. Blackwell, J. P. Gerdt, T. Schell, 2015, Organic & biomolecular chemistry.

Chemical Control of Quorum Sensing in E. coli: Identification of Small Molecule Modulators of SdiA and Mechanistic Characterization of a Covalent Inhibitor.

Ying Ge, H. Blackwell, Trisha Tucholski, 2020, ACS infectious diseases.

Non-Native Peptides Capable of Pan-Activating the agr Quorum Sensing System across Multiple Specificity Groups of Staphylococcus epidermidis.

Tian Yang, H. Blackwell, A. Horswill, 2021, ACS chemical biology.

Conformational Switch to a β-turn in a Staphylococcal Quorum Sensing Signal Peptide Causes a Dramatic Increase in Potency.

Gabriel Cornilescu, M. Tonelli, Tian Yang, 2019, Journal of the American Chemical Society.

Non-native acylated homoserine lactones reveal that LuxIR quorum sensing promotes symbiont stability.

E. Ruby, H. Blackwell, Julia A. Schwartzman, 2014, Environmental microbiology.

Synthesis and characterization of nitroaromatic peptoids: fine tuning peptoid secondary structure through monomer position and functionality.

H. Blackwell, Sarah A. Fowler, Rinrada Luechapanichkul, 2009, The Journal of organic chemistry.

Design and conformational analysis of peptoids containing N-hydroxy amides reveals a unique sheet-like secondary structure.

H. Blackwell, I. Guzei, Joseph R. Stringer, 2011, Biopolymers.

Periprosthetic bacterial biofilm and quorum sensing

A. Barron, D. Amanatullah, H. Blackwell, 2018, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

Structure-Based Design and Biological Evaluation of Triphenyl Scaffold-Based Hybrid Compounds as Hydrolytically Stable Modulators of a LuxR-Type Quorum Sensing Receptor

H. Blackwell, Matthew C. O’Reilly, 2015, ACS infectious diseases.

Mutational analysis of the quorum-sensing receptor LasR reveals interactions that govern activation and inhibition by nonlactone ligands.

H. Blackwell, J. P. Gerdt, F. M. Rossi, 2014, Chemistry & biology.

Design and synthesis of macrocyclic peptomers as mimics of a quorum sensing signal from Staphylococcus aureus.

H. Blackwell, Sarah A. Fowler, Danielle M Stacy, 2008, Organic letters.

The State of the Union Is Strong: a Review of ASM's 6th Conference on Cell-Cell Communication in Bacteria

Sam P. Brown, H. Blackwell, B. Hammer, 2018, Journal of bacteriology.

Simplified AIP‐II Peptidomimetics Are Potent Inhibitors of Staphylococcus aureus AgrC Quorum Sensing Receptors

Gabriel Cornilescu, H. Blackwell, Yftah Tal‐Gan, 2017, Chembiochem : a European journal of chemical biology.

Structure-Function Analyses of a Staphylococcus epidermidis Autoinducing Peptide Reveals Motifs Critical for AgrC-type Receptor Modulation.

Tian Yang, H. Blackwell, A. Horswill, 2016, ACS chemical biology.

Characterization of structural elements in native autoinducing peptides and non-native analogues that permit the differential modulation of AgrC-type quorum sensing receptors in Staphylococcus aureus.

Gabriel Cornilescu, H. Blackwell, Yftah Tal‐Gan, 2016, Organic & biomolecular chemistry.

N-Methyl and peptoid scans of an autoinducing peptide reveal new structural features required for inhibition and activation of AgrC quorum sensing receptors in Staphylococcus aureus.

H. Blackwell, Yftah Tal‐Gan, Danielle M Stacy, 2014, Chemical communications.

Characterization of an Autoinducing Peptide Signal Reveals Highly Efficacious Synthetic Inhibitors and Activators of Quorum Sensing and Biofilm Formation in Listeria monocytogenes.

J. Sauer, Ying Ge, H. Blackwell, 2023, Biochemistry.

Highly Stable, Amide-Bridged Autoinducing Peptide Analogues that Strongly Inhibit the AgrC Quorum Sensing Receptor in Staphylococcus aureus.

Gabriel Cornilescu, Tian Yang, H. Blackwell, 2016, Angewandte Chemie.

Surface‐Mediated Release of a Small‐Molecule Modulator of Bacterial Biofilm Formation: A Non‐Bactericidal Approach to Inhibiting Biofilm Formation in Pseudomonas aeruginosa

Helen E Blackwell, D. M. Lynn, H. Blackwell, 2013, Advanced healthcare materials.

The state of the union is strong : A review of ASM ’ s 6 th conference on Cell-cell Communication 1 in Bacteria 2 3 4 5 6

Sam P. Brown, H. Blackwell, B. Hammer, 2018 .