P. Clegg

J. Vandeweerd, P. Clegg, N. Kirschvink, 2017, Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association.

Characterization of neopeptides in equine articular cartilage degradation

P. Clegg, M. Peffers, D. Thornton, 2015, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

Prevalence of naturally occurring cartilage defects in the ovine knee.

J. Vandeweerd, P. Gustin, P. Clegg, 2012, Osteoarthritis and cartilage.

Vancomycin Resistant Enterococci (VRE) in equine-faecal samples

N. Williams, Mohamed O Ahmed, P. Clegg, 2011 .

Mesenchymal stem cell therapy in equine musculoskeletal disease: scientific fact or clinical fiction?

P. Clegg, R. Smith, S. E. Taylor, 2007, Equine veterinary journal.

Magnetic resonance compositional imaging of articular cartilage: What can we expect in veterinary medicine?

J. Vandeweerd, P. Clegg, S. Tew, 2015, Veterinary journal.

Osteomyelitis in the Veterinary Species

P. Clegg, 2011 .

Differential regulation of the GLUT1 and GLUT3 glucose transporters by growth factors and pro-inflammatory cytokines in equine articular chondrocytes.

A. Mobasheri, P. Clegg, S. Carter, 2005, Veterinary journal.

Effects of hypoxia on glucose transport in primary equine chondrocytes in vitro and evidence of reduced GLUT1 gene expression in pathologic cartilage in vivo

A. Mobasheri, S. Carter, P. Clegg, 2009, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

Cross platform analysis of transcriptomic data identifies ageing has distinct and opposite effects on tendon in males and females

S. Cockell, P. Clegg, M. Peffers, 2017, Scientific Reports.

Cross-species gene modules emerge from a systems biology approach to osteoarthritis

P. Clegg, A. Mueller, S. Tew, 2017, npj Systems Biology and Applications.

A survey of health care and disease in geriatric horses aged 30 years or older.

G. Pinchbeck, P. Clegg, C. McGowan, 2012, Veterinary journal.

Disease prevalence in geriatric horses in the United Kingdom: veterinary clinical assessment of 200 cases.

G. Pinchbeck, P. Clegg, C. McGowan, 2012, Equine veterinary journal.

A systems biology approach to defining regulatory mechanisms for cartilage and tendon cell phenotypes

P. Clegg, A. Mueller, O. Vasieva, 2016, Scientific Reports.

Donor age affects proteome composition of tenocyte-derived engineered tendon

P. Clegg, M. Peffers, J. Anderson, 2018, BMC Biotechnology.

Comprehensive protein profiling of synovial fluid in osteoarthritis following protein equalization

P. Clegg, M. Peffers, C. Riggs, 2014, Osteoarthritis and cartilage.

An exploration of the ability of tepoxalin to ameliorate the degradation of articular cartilage in a canine in vitro model

P. Clegg, J. Innes, A. Vaughan-Thomas, 2009, BMC veterinary research.

Optimization of Synovial Fluid Collection and Processing for NMR Metabolomics and LC-MS/MS Proteomics

Simon W. Jones, P. Clegg, M. Peffers, 2020, Journal of Proteome Research.

Therapeutic Potential of Dental Pulp Stem Cells and Leukocyte- and Platelet-Rich Fibrin for Osteoarthritis

J. Vandeweerd, P. Clegg, P. Gervois, 2020, Cells.

The effect of exercise on the protein profile of rat knee joint intra- and extra-articular ligaments

D. Simpson, H. Birch, P. Clegg, 2020, bioRxiv.

Is evidence-based medicine so evident in veterinary research and practice? History, obstacles and perspectives.

C. Saegerman, J. Vandeweerd, P. Gustin, 2012, Veterinary journal.

Decoding the Regulatory Landscape of Ageing in Musculoskeletal Engineered Tissues Using Genome-Wide DNA Methylation and RNASeq

Yongxiang Fang, P. Clegg, M. Peffers, 2016, PloS one.

Leptin expression in dogs with cardiac disease and congestive heart failure.

P. Clegg, S. Tew, J. Dukes-McEwan, 2011, Journal of veterinary internal medicine.

MT3-MMP (MMP-16) is Downregulated by In Vitro Cytokine Stimulation of Cartilage, but Unaltered in Naturally Occurring Equine Osteoarthritis and Osteochondrosis

P. Clegg, C. Redmond, A. Vaughan-Thomas, 2008, Connective tissue research.

Effect of corticosteroids on articular cartilage: have animal studies said everything?

L. Zhihong, J. Vandeweerd, P. Gustin, 2015, Fundamental & clinical pharmacology.

Canine TIMP-2: Purification, Characterization and Molecular Detection

P. Clegg, D. Robertson, S. Carter, 2000 .

Current Knowledge on Equine Musculoskeletal Biomarkers and Future Needs : A White Paper

M. Vaudin, C. Kawcak, C. Little, 2014 .

Science in brief: Report on the Havemeyer Foundation workshop on equine musculoskeletal biomarkers--current knowledge and future needs.

P. Clegg, C. McIlwraith, 2014, Equine veterinary journal.

Carriage of Staphylococcus species in the veterinary visiting dog population in mainland UK: molecular characterisation of resistance and virulence.

M. Fielder, G. Pinchbeck, S. Dawson, 2014, Veterinary microbiology.

Muc5b Is the Major Polymeric Mucin in Mucus from Thoroughbred Horses With and Without Airway Mucus Accumulation

P. Clegg, D. Thornton, J. Cardwell, 2011, PloS one.

High-intensity exercise induces structural, compositional and metabolic changes in cuboidal bones--findings from an equine athlete model.

P. Clegg, N. Avery, J. Tarlton, 2008, Bone.

The use of computed tomography to assist orthopaedic surgery in 86 horses (2002–2010)

F. Desbrosse, P. Clegg, R. Perrin, 2011 .

The in vitro effects of antibiotics on cell viability and gene expression of equine bone marrow-derived mesenchymal stromal cells.

P. Clegg, R. Parker, S. E. Taylor, 2012, Equine veterinary journal.

Cultivation of human tenocytes in high-density culture

A. Mobasheri, G. Schulze-Tanzil, M. Shakibaei, 2004, Histochemistry and Cell Biology.

Methicillin-resistant Staphylococci in Companion Animals

S. Dawson, P. Clegg, C. Hart, 2005, Emerging infectious diseases.

Characterisation of equine matrix metalloproteinase 2 and 9; and identification of the cellular sources of these enzymes in joints.

P. Clegg, S. Carter, C. Riggs, 1997, Equine veterinary journal.

A comparison of 3-T magnetic resonance imaging and computed tomography arthrography to identify structural cartilage defects of the fetlock joint in the horse.

J. Vandeweerd, P. Clegg, N. Antoine, 2014, Veterinary journal.

Longitudinal study of antimicrobial-resistant commensal Escherichia coli in the faeces of horses in an equine hospital.

G. Pinchbeck, S. Dawson, N. Williams, 2011, Preventive veterinary medicine.

Collection and propagation methods for mesenchymal stromal cells.

P. Clegg, Sarah E. Taylor, S. Taylor, 2011, The Veterinary clinics of North America. Equine practice.

The organisation of elastin and fibrillins 1 and 2 in the cruciate ligament complex

D. Spiller, P. Clegg, J. Innes, 2011, Journal of anatomy.

Ageing does not result in a decline in cell synthetic activity in an injury prone tendon

A. Goodship, H. Birch, P. Clegg, 2016, Scandinavian journal of medicine & science in sports.

Microscopic localization of active gelatinases in equine osteochondritis dissecans (OCD) cartilage.

P. Clegg, S. Carter, F. Al-hizab, 2002, Osteoarthritis and cartilage.

Biomarkers of cartilage turnover. Part 1: Markers of collagen degradation and synthesis.

P. Clegg, J. Innes, A. Vaughan-Thomas, 2010, Veterinary journal.

Chondrocyte apoptosis, inflammatory mediators and equine osteoarthritis.

A. Mobasheri, P. Clegg, 2003, Veterinary journal.

Antimicrobial resistance in equine faecal Escherichia coli isolates from North West England

N. Williams, Mohamed O Ahmed, P. Clegg, 2010, Annals of Clinical Microbiology and Antimicrobials.

Researchresistance in equine faecal Escherichia coli isolates from North West England

N. Williams, Mohamed O Ahmed, P. Clegg, 2010 .

ResearchAntimicrobial resistance in equine faecal Escherichia coli isolates from North West England

N. Williams, Mohamed O Ahmed, P. Clegg, 2010 .

Gene expression analysis of subchondral bone, cartilage, and synovium in naturally occurring equine palmar/plantar osteochondral disease

A. Boyde, G. Pinchbeck, P. Clegg, 2021, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

Ultrasound anatomy of the normal stifle in the sheep

J. Vandeweerd, A. Dugdale, P. Clegg, 2018, Anatomia, histologia, embryologia.

Ligament-Derived Stem Cells: Identification, Characterisation, and Therapeutic Application

P. Clegg, E. Canty-Laird, E. Comerford, 2017, Stem cells international.

Elastin content is high in the canine cruciate ligament and is associated with degeneration

P. Clegg, J. Innes, E. Comerford, 2014, Veterinary journal.

Osteoarthritis--what hope for effective therapy?

P. Clegg, S. Carter, C. Riggs, 1997, Equine veterinary journal.

MMP‐mediated collagen breakdown induced by activated protein C in equine cartilage is reduced by corticosteroids

P. Clegg, C. Redmond, A. Vaughan-Thomas, 2010, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

Matrix metalloproteinases 2 and 9 in equine synovial fluids.

P. Clegg, S. Carter, C. Riggs, 1997, Equine veterinary journal.

Carriage of antimicrobial resistant Escherichia coli in dogs: Prevalence, associated risk factors and molecular characteristics.

G. Pinchbeck, S. Dawson, N. Williams, 2017, Veterinary microbiology.

Matrix metalloproteinase-2 and -9 are activated in joint diseases.

P. Clegg, S. Carter, P. D. Clegg, 1999, Equine veterinary journal.

The effect of drugs commonly used in the treatment of equine articular disorders on the activity of equine matrix metalloproteinase-2 and 9.

P. Clegg, S. Carter, M. Jones, 1998, Journal of veterinary pharmacology and therapeutics.

Equine TIMP-1 and TIMP-2: identification, activity and cellular sources.

P. Clegg, S. Carter, A. Coughlan, 1998, Equine veterinary journal.

Magnetic resonance imaging (MRI) anatomy of the ovine stifle.

J. Vandeweerd, P. Clegg, N. Kirschvink, 2013, Veterinary surgery : VS.

Cartilage damage involving extrusion of mineralisable matrix from the articular calcified cartilage and subchondral bone.

A. Boyde, G. Pinchbeck, P. Clegg, 2011, European cells & materials.

A review of the characteristics and treatment of methicillin-resistant Staphylococcus aureus (MRSA) in the horse and a case series of MRSA infection in four horses

G. Pinchbeck, S. Dawson, N. Williams, 2010 .

Quantitative analysis of voltage-gated potassium currents from primary equine (Equus caballus) and elephant (Loxodonta africana) articular chondrocytes.

A. Mobasheri, P. Clegg, T. Gent, 2005, American journal of physiology. Regulatory, integrative and comparative physiology.

Antimicrobial resistance in clinical bacterial isolates from horses in the UK.

G. Pinchbeck, N. Williams, P. Clegg, 2021, Equine veterinary journal.

Emergence of carriage of CTX-M-15 in faecal Escherichia coli in horses at an equine hospital in the UK; increasing prevalence over a decade (2008–2017)

G. Pinchbeck, N. Williams, E. Winward, 2019, BMC Veterinary Research.

Evaluation of cartilage, synovium and adipose tissue as cellular sources for osteochondral repair.

P. Clegg, J. Innes, N. Rhodes, 2013, Veterinary journal.

Validation of a client-based clinical metrology instrument for the evaluation of canine elbow osteoarthritis.

G. Pinchbeck, P. Clegg, J. Innes, 2009, The Journal of small animal practice.

Absolute Quantification of Selected Proteins in the Human Osteoarthritic Secretome

R. Beynon, P. Clegg, M. Peffers, 2013, International journal of molecular sciences.

Biomarkers of cartilage turnover. Part 2: Non-collagenous markers.

P. Clegg, J. Innes, E. Garvican, 2010, Veterinary journal.

Synovial Fluid Metabolites Differentiate between Septic and Nonseptic Joint Pathologies

P. Clegg, M. Peffers, J. Anderson, 2018, Journal of proteome research.

Proposed definitions and criteria for reporting time frame, outcome, and complications for clinical orthopedic studies in veterinary medicine.

M. Conzemius, R. Evans, A. Kapatkin, 2010, Veterinary surgery : VS.

Treatment of sepsis in the small tarsal joints of 11 horses with gentamicin-impregnated polymethylmethacrylate beads

P. Clegg, R. Smith, M. Schramme, 2001, Veterinary Record.

Antimicrobial resistance changes in enteric Escherichia coli of horses during hospitalisation: resistance profiling of isolates.

R. Christley, N. Williams, P. Clegg, 2013, Veterinary journal.

Matrix assisted laser desorption ionization mass spectrometry imaging identifies markers of ageing and osteoarthritic cartilage

Gert B. Eijkel, R. Heeren, B. Cillero-Pastor, 2014, Arthritis Research & Therapy.

Biofilms and their relevance to veterinary medicine.

P. Clegg, S. Percival, D. Knottenbelt, 2007, Veterinary microbiology.

Analysis of horse race videos to identify intra-race risk factors for fatal distal limb fracture.

T D H Parkin, P. Clegg, K. Morgan, 2006, Preventive veterinary medicine.

Whip use and race progress are associated with horse falls in hurdle and steeplechase racing in the UK.

G. Pinchbeck, P. Clegg, K. Morgan, 2010, Equine veterinary journal.

The interfascicular matrix enables fascicle sliding and recovery in tendon, and behaves more elastically in energy storing tendons

H. Birch, P. Clegg, H. Screen, 2015, Journal of the mechanical behavior of biomedical materials.

Cross-sectional study of antimicrobial-resistant bacteria in horses. Part 1: Prevalence of antimicrobial-resistant Escherichia coli and methicillin-resistant Staphylococcus aureus.

P. Diggle, G. Pinchbeck, S. Dawson, 2012, Equine veterinary journal.

Antimicrobial resistance in bacteria from horses: Epidemiology of antimicrobial resistance.

G. Pinchbeck, N. Williams, P. Clegg, 2015, Equine veterinary journal.

A test of the universal applicability of a commonly used principle of hoof balance.

G. Pinchbeck, K. Kissick, P. Clegg, 2016, Veterinary journal.

Comparison of owner-reported health problems with veterinary assessment of geriatric horses in the United Kingdom.

G. Pinchbeck, P. Clegg, C. McGowan, 2012, Equine veterinary journal.

Expression of purinergic P2X receptor subtypes 1, 2, 3 and 7 in equine laminitis.

P. Clegg, M. Senior, P. Milner, 2013, Veterinary journal.

Endoscopic electrosurgical excision of laryngeal granulation tissue in a standing pregnant mare

P. Clegg, D. Knottenbelt, D. Kelly, 2000, Veterinary Record.

Chronic equine laminitis is characterised by loss of GLUT1, GLUT4 and ENaC positive laminar keratinocytes.

A. Mobasheri, P. Clegg, C. Canessa, 2010, Equine veterinary journal.

Alveolar rhabdomyosarcoma: an unusual cause of lameness in a pony.

P. Clegg, A. Coumbe, 1993, Equine veterinary journal.

Stem cells in veterinary medicine--attempts at regenerating equine tendon after injury.

P. Clegg, J. Dudhia, Roger K. Smith, 2007, Trends in biotechnology.

Treatment of septic common digital extensor tenosynovitis by complete resection in seven horses.

P. Clegg, J. Abbot, E. Singer, 2004, Veterinary surgery : VS.

Computed Tomography and Magnetic Resonance Anatomy of the Normal Orbit and Eye of the Horse

J. Vandeweerd, P. Clegg, T. Launois, 2015, Anatomia, histologia, embryologia.

Musculoskeletal disease and injury, now and in the future. Part 1: fractures and fatalities.

P. Clegg, 2011, Equine veterinary journal.

Advances in the understanding of tendinopathies: a report on the Second Havemeyer Workshop on equine tendon disease.

S. Dakin, M. Kjaer, N. Crevier-Denoix, 2014, Equine veterinary journal.

Cross-sectional study of antimicrobial-resistant bacteria in horses. Part 2: Risk factors for faecal carriage of antimicrobial-resistant Escherichia coli in horses.

G. Pinchbeck, S. Dawson, N. Williams, 2012, Equine veterinary journal.

Distribution of proteins within different compartments of tendon varies according to tendon type

H. Birch, P. Clegg, H. Screen, 2016, Journal of anatomy.

Anatomical heterogeneity of tendon: Fascicular and interfascicular tendon compartments have distinct proteomic composition

D. Simpson, P. Clegg, H. Screen, 2016, Scientific Reports.

The role of the non‐collagenous matrix in tendon function

H. Birch, P. Clegg, H. Screen, 2013, International journal of experimental pathology.

Unilateral hindlimb swelling may be a sign of serious disseminated neoplasia in horses

P. Clegg, D. Knottenbelt, 2010 .

Desflurane in equine anaesthesia: a preliminary trial

Noah J. Jones, P. Clegg, K. Clarke, 1995, Veterinary Record.

Post anaesthetic colic in horses: a preventable complication?

G. Pinchbeck, A. Dugdale, P. Clegg, 2010, Equine veterinary journal.

Retrospectoive Study the risk factors and prevalence of colic in horses after orthopaedic surgery

G. Pinchbeck, A. Dugdale, P. Clegg, 2004, Veterinary Record.

Reported morbidities following 861 anaesthetics given at four equine hospitals

G. Pinchbeck, A. Dugdale, P. Clegg, 2007, Veterinary Record.

Identification of Equid herpesvirus 2 in tissue-engineered equine tendon

J. Stewart, A. Radford, P. Clegg, 2017, Wellcome Open Research.

Stem Cells for Cartilage Repair: Preclinical Studies and Insights in Translational Animal Models and Outcome Measures

J. Vandeweerd, P. Clegg, P. Gervois, 2018, Stem cells international.

Proteomic analysis of polymeric salivary mucins: no evidence for MUC19 in human saliva.

D. Rogers, P. Clegg, D. Thornton, 2008, The Biochemical journal.

Muc5b and Muc5ac are the major oligomeric mucins in equine airway mucus.

P. Clegg, D. Thornton, S. Mckane, 2007, American journal of physiology. Lung cellular and molecular physiology.

Serum snoRNAs as biomarkers for joint ageing and post traumatic osteoarthritis

Peter D. Clegg, Yongxiang Fang, P. Clegg, 2017, Scientific Reports.

Differential tissue specific, temporal and spatial expression patterns of the Aggrecan gene is modulated by independent enhancer elements

P. Clegg, George Bou-Gharios, A. Neal, 2018, Scientific Reports.

miR-24:Prdx6 interactions regulate oxidative stress and viability of myogenic progenitors during ageing

E. McCloskey, P. Clegg, I. Bellantuono, 2021, bioRxiv.

MicroRNA Profiling in Cartilage Ageing

Yongxiang Fang, P. Clegg, M. Peffers, 2017, International journal of genomics.

Polymorphisms of the equine major histocompatibility complex class II DRA locus.

S. Eyre, W. Thomson, W. Ollier, 2004, Tissue antigens.

Influence of Ageing on Tendon Homeostasis.

H. Birch, P. Clegg, M. Peffers, 2016, Advances in experimental medicine and biology.

Transcriptome analysis of ageing in uninjured human Achilles tendon

Yongxiang Fang, H. Birch, P. Clegg, 2015, Arthritis Research & Therapy.

P. Clegg, M. Peffers, C. Proctor, 2016, European cells & materials.

Septic tenosynovitis of the tarsal sheath of an Arab gelding and suspected sepsis of the lateral digital flexor tendon subsequent to bacterial peritonitis

P. Clegg, G. Edwards, D. Archer, 2004, Veterinary Record.

Magnetic Resonance Imaging (MRI) Anatomy of the Ovine Lumbar Spine

P. Clegg, N. Kirschvink, F. Hontoir, 2014, Anatomia, histologia, embryologia.

Specialization of tendon mechanical properties results from interfascicular differences

H. Birch, P. Clegg, H. Screen, 2012, Journal of The Royal Society Interface.

Equine synovial fluid small non-coding RNA signatures in early osteoarthritis

Yongxiang Fang, P. Clegg, M. Peffers, 2020, bioRxiv.

Transcriptome-Wide Analysis of Messenger RNA Decay in Normal and Osteoarthritic Human Articular Chondrocytes

P. Clegg, M. Peffers, S. Tew, 2014, Arthritis & rheumatology.

Identification and Characterization of Canine Ligament Progenitor Cells and Their Extracellular Matrix Niche.

D. Simpson, P. Clegg, E. Canty-Laird, 2019, Journal of proteome research.

A cross-sectional study of geriatric horses in the United Kingdom. Part 1: Demographics and management practices.

G. Pinchbeck, P. Clegg, C. McGowan, 2011, Equine veterinary journal.

A review of tendon injury: why is the equine superficial digital flexor tendon most at risk?

H. Birch, P. Clegg, C. Thorpe, 2010, Equine veterinary journal.

Matrix metabolism rate differs in functionally distinct tendons.

H. Birch, P. Clegg, S. Strassburg, 2007, Matrix biology : journal of the International Society for Matrix Biology.

98 Early Inflammatory Response Of Tenocytes To Overload

H. Birch, P. Clegg, H. Screen, 2014, British Journal of Sports Medicine.

Musculoskeletal disease and injury, now and in the future. Part 2: Tendon and ligament injuries.

P. Clegg, 2012, Equine veterinary journal.

Evidence-based medicine and stem cell therapy: how do we know such technologies are safe and efficacious?

G. Pinchbeck, P. Clegg, 2011, The Veterinary clinics of North America. Equine practice.

A study of the anatomy and injection techniques of the ovine stifle by positive contrast arthrography, computed tomography arthrography and gross anatomical dissection.

P. Bonnet, J. Vandeweerd, E. Depiereux, 2012, Veterinary journal.

Risk of fatal distal limb fractures among thoroughbreds involved in the five tpes of racing in the United Kingdom

P. M. Webbon, P. Clegg, K. Morgan, 2004, Veterinary Record.

Ex vivo study correlating the stiffness of the ovine patellar tendon to age and weight

J. Vandeweerd, A. Dugdale, B. Innocenti, 2022, International biomechanics.

Intrafascicular chondroid‐like bodies in the ageing equine superficial digital flexor tendon comprise glycosaminoglycans and type II collagen

P. Clegg, T. Maddox, E. Canty-Laird, 2021, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

Variations during ageing in the three-dimensional anatomical arrangement of fascicles within the equine superficial digital flexor tendon.

P. Clegg, E. Canty-Laird, E. Comerford, 2018, European cells & materials.

Resection of the common digital extensor tendon in a gelding

P. Clegg, E. Singer, M. Cheeseman, 2000, Veterinary Record.

Cell phenotypic variation in normal and damaged tendons

P. Clegg, S. Strassburg, Roger K. Smith, 2007, International journal of experimental pathology.

The effect of exercise on the protein profile of rat knee joint intra‐ and extra‐articular ligaments

D. Simpson, H. Birch, P. Clegg, 2018, Scandinavian journal of medicine & science in sports.

Proteomic Analysis Reveals Age-related Changes in Tendon Matrix Composition, with Age- and Injury-specific Matrix Fragmentation

P. Clegg, H. Screen, M. Peffers, 2014, The Journal of Biological Chemistry.

Characterisation of key proteoglycans in the cranial cruciate ligaments (CCLs) from two dog breeds with different predispositions to CCL disease and rupture.

P. Clegg, S. Tew, C. Hughes, 2021, Veterinary journal.

Variation in the Quantity of Elastic Fibres with Degeneration in Canine Cranial Cruciate Ligaments from Labrador Retrievers

P. Clegg, J. Innes, D. Clements, 2017, Veterinary and Comparative Orthopaedics and Traumatology.

Variations in cell morphology in the canine cruciate ligament complex.

D. Spiller, P. Clegg, J. Innes, 2012, Veterinary journal.

Clinical aspects of the equine shoulder and elbow joints

P. Clegg, E. Garvican, 2008 .

Local anaesthetics or their combination with morphine and/or magnesium sulphate are toxic for equine chondrocytes and synoviocytes in vitro

P. Clegg, M. Peffers, L. Rubio‐Martínez, 2017, BMC Veterinary Research.

Communication between the distal interphalangeal joint and the navicular bursa in the horse at Computed Tomography Arthrography

J. Vandeweerd, P. Clegg, C. Nicaise, 2019, Anatomia, histologia, embryologia.

Severe distal interphalangeal joint synovitis in a Thoroughbred cross mare

P. Clegg, 1996 .

J.A. Butler, C.M. Colles, S.J. Dyson, S.E. Kold, P.W. Poulos, Clinical Radiology of the Horse, third ed., Wiley Blackwell, 2008, ISBN101405171081, 748 pp.; £139.50 (hard)

P. Clegg, 2009 .

Use of computed tomography to diagnose new bone formation associated with desmitis of the proximal aspect of the suspensory ligament in third metacarpal or third metatarsal bones of three horses.

J. Vandeweerd, F. Desbrosse, P. Clegg, 2009, Journal of the American Veterinary Medical Association.

Subluxation of the left elbow joint in a pony at induction of general anaesthesia

P. Clegg, M. Senior, M. Smith, 2002, Veterinary Record.

Scapulohumeral osteoarthritis in 20 Shetland ponies, miniature horses and falabella ponies

P. Clegg, S. Dyson, M. Schramme, 2001, Veterinary Record.

Pathological and clinical features associated with palmar/plantar osteochondral disease of the metacarpo/metatarsophalangeal joint in Thoroughbred racehorses.

A. Boyde, G. Pinchbeck, P. Clegg, 2013, Equine veterinary journal.

Post mortem evaluation of palmar osteochondral disease (traumatic osteochondrosis) of the metacarpo/metatarsophalangeal joint in Thoroughbred racehorses.

A. Boyde, G. Pinchbeck, P. Clegg, 2009, Equine veterinary journal.

Catastrophic fracture of the lateral condyle of the third metacarpus/metatarsus in UK racehorses - fracture descriptions and pre-existing pathology.

P. Clegg, K. Morgan, T. Parkin, 2006, Veterinary journal.

Equine flexor tendon imaging part 2: Current status and future directions in advanced diagnostic imaging, with focus on the deep digital flexor tendon.

P. Clegg, T. Maddox, A. Ehrle, 2021, Veterinary journal.

How can veterinarians base their medical decisions on the best available scientific evidence?

J. Vandeweerd, P. Clegg, S. Buczinski, 2012, The Veterinary clinics of North America. Food animal practice.

A cross-sectional study of geriatric horses in the United Kingdom. Part 2: Health care and disease.

G. Pinchbeck, P. Clegg, C. McGowan, 2011, Equine veterinary journal.

Cytokine and matrix metalloproteinase expression in blood samples of dogs with congestive heart failure.

P. Clegg, S. Tew, J. Dukes-McEwan, 2010 .

Aspartic Acid Racemization and Collagen Degradation Markers Reveal an Accumulation of Damage in Tendon Collagen That Is Enhanced with Aging*

Ian Streeter, Helen L Birch, Allen E Goodship, 2010, The Journal of Biological Chemistry.

Skeletal scintigraphy in the horse: current indications and validity as a diagnostic test.

P. Clegg, D. Archer, L. Voute, 2007, Veterinary journal.

Post-transcriptional gene regulation following exposure of osteoarthritic human articular chondrocytes to hyperosmotic conditions.

P. Clegg, M. Peffers, O. Vasieva, 2011, Osteoarthritis and cartilage.

Analysis of post transcriptional regulation of SOX9 mRNA during in vitro chondrogenesis.

P. Clegg, S. Tew, Simon R Tew, 2011, Tissue engineering. Part A.

TNF-alpha SNP haplotype frequencies in equidae.

W. Thomson, W. Ollier, G. Pinchbeck, 2006, Tissue antigens.

Endoscopic resection of dorsal spinous processes and interspinous ligament in ten horses.

J. Vandeweerd, F. Desbrosse, P. Clegg, 2007, Veterinary surgery : VS.

Innervation and nerve injections of the lumbar spine of the horse: a cadaveric study.

F. Desbrosse, P. Clegg, P. Cripps, 2007, Equine veterinary journal.

Tendon extracellular matrix damage, degradation and inflammation in response to in vitro overload exercise

Saira Chaudhry, Chavaunne T. Thorpe, Peter D. Clegg, 2015, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

Systematic review of efficacy of nutraceuticals to alleviate clinical signs of osteoarthritis.

C. Saegerman, J. Vandeweerd, C. Cambier, 2012, Journal of veterinary internal medicine.

Treatment of a coxofemoral luxation secondary to upward fixation of the patella in a Shetland pony

P. Clegg, R. Butson, 1996, Veterinary Record.

Haemoperitoneum in horses: a retrospective review of 54 cases

P. Clegg, R. Pirie, R S Pirie, 2010, Veterinary Record.

Effect of age at presentation on outcome following arthroscopic debridement of subchondral cystic lesions of the medial femoral condyle: 85 horses (1993--2003).

G. Pinchbeck, P. Clegg, D. Richardson, 2010, Equine veterinary journal.

Treatment of recurrent luxation of the shoulder in an alpaca

A. Dugdale, P. Clegg, E. Wawra, 2007, Veterinary Record.

Aquaporin water channels AQP1 and AQP3, are expressed in equine articular chondrocytes.

A. Mobasheri, P. Clegg, S. Carter, 2004, Veterinary journal.

Antibiotic Resistance Patterns in Faecal E. coli: A Longitudinal Cohort-Control Study of Hospitalized Horses

N. Williams, Mohamed O Ahmed, P. Clegg, 2012 .

Restricted differentiation potential of progenitor cell populations obtained from the equine superficial digital flexor tendon (SDFT)

P. Clegg, E. Canty-Laird, E. Comerford, 2015, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

Identification of Disease Specific Metabolic Fingerprints in Early Osteoarthritis

P. Clegg, M. Peffers, M. Phelan, 2015 .

Clinical findings associated with chronic ischial fracture in a gelding.

P. Clegg, T. Booth, 2000, Australian veterinary journal.

Case-control study to investigate risk factors for horse falls in hurdle racing in England and Wales

G. Pinchbeck, P. Clegg, K. Morgan, 2003, Veterinary Record.

Active synthesis of type I collagen homotrimer in Dupuytren’s fibrosis is unaffected by anti-TNF-α treatment

D. Simpson, P. Clegg, G. Cheung, 2020, bioRxiv.

An anatomic study of the calcaneal bursae in the horse.

P. Clegg, E. Singer, E. M. Post, 2007, Veterinary surgery : VS.

Retrospective study of 24 cases of septic calcaneal bursitis in the horse.

P. Clegg, R. Smith, P. Cripps, 2010, Equine veterinary journal.

Nutraceutical Therapies for Degenerative Joint Diseases: A Critical Review

A. Mobasheri, M. Shakibaei, P. Clegg, 2005, Critical reviews in food science and nutrition.

Antimicrobial resistance in the horse - EVJ's online collection.

P. Clegg, I. Bowen, 2015, Equine veterinary journal.

Special Focus on Antimicrobial Resistance

P. Clegg, I. Bowen, 2015 .

THREE-DIMENSIONAL ANATOMY OF EQUINE SUPERFICIAL DIGITAL FLEXOR TENDON (SDFT)

P. Clegg, E. Comerford, E.G. Canty-Laird, 2015 .

Fascicles and the interfascicular matrix show adaptation for fatigue resistance in energy storing tendons

H. Birch, P. Clegg, H. Screen, 2016, Acta biomaterialia.

Regulation of SOX9 in normal and osteoarthritic equine articular chondrocytes by hyperosmotic loading

P. Clegg, M. Peffers, S. Tew, 2010, Osteoarthritis and cartilage.

Post-transcriptional gene regulation in chondrocytes.

P. Clegg, S. Tew, 2010, Biochemical Society transactions.

A topographic anatomical study of the equine epiploic foramen and comparison with laparoscopic visualisation.

P. Clegg, W. Van den Broeck, P. Cornillie, 2015, Equine veterinary journal.

Primary retroperitoneal tumour in a horse.

P. Clegg, P D Clegg, J S McKay, 2010, Equine veterinary journal.

Is the T-ligament a ligament? A histological study in equine cadaver forelimbs.

J. Vandeweerd, A. Dugdale, P. Clegg, 2020, Research in veterinary science.

Differential diagnosis of a swollen hock in the horse

P. Clegg, 2003, In Practice.

Comparative rheumatology: what can be learnt from naturally occurring musculoskeletal disorders in domestic animals?

P. Clegg, J. Innes, 2010, Rheumatology.

J. Vandeweerd, P. Clegg, N. Kirschvink, 2019, Anatomia, histologia, embryologia.

Online papers Oct 2.indd

P. Clegg, R. Pirie, T. Mair, 2010 .

Horse injuries and racing practices in National Hunt racehorses in the UK: the results of a prospective cohort study.

G. Pinchbeck, P. Clegg, K. Morgan, 2004, Veterinary journal.

Understanding veterinary practitioners' decision-making process: implications for veterinary medical education.

C. Saegerman, J. Vandeweerd, C. Cambier, 2012, Journal of veterinary medical education.

Destructive lesions of the proximal sesamoid bones as a complication of dorsal metatarsal artery catheterization in three horses.

P. Clegg, E. Singer, E. Barr, 2005, Veterinary surgery : VS.

A prospective cohort study to investigate risk factors for horse falls in UK hurdle and steeplechase racing.

G. Pinchbeck, P. Clegg, K. Morgan, 2010, Equine veterinary journal.

Prevalence of Age-Related Changes in Ovine Lumbar Intervertebral Discs during Computed Tomography and Magnetic Resonance Imaging.

J. Vandeweerd, A. Dugdale, P. Clegg, 2016, Comparative medicine.

Ex Vivo Equine Cartilage Explant Osteoarthritis Model: A Metabolomics and Proteomics Study

P. Clegg, M. Peffers, J. Anderson, 2020, Journal of proteome research.

Ex-Vivo Equine Cartilage Explant Osteoarthritis Model - A Metabolomics and Proteomics Study

P. Clegg, M. Peffers, J. Anderson, 2020, bioRxiv.

The interfascicular matrix of energy storing tendons houses heterogenous cell populations disproportionately affected by ageing

H. Birch, P. Clegg, H. Screen, 2023, bioRxiv.

A proteomic analysis of chondrogenic, osteogenic and tenogenic constructs from ageing mesenchymal stem cells

P. Clegg, M. Peffers, C. Proctor, 2016, Stem cell research & therapeutics.

The role of endogenous and exogenous enzymes in chronic wounds: A focus on the implications of aberrant levels of both host and bacterial proteases in wound healing

P. Clegg, S. Percival, C. Cochrane, 2012, Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society.

Evidence and Significance of Biofilms in Chronic Wounds in Horses

P. Clegg, S. Percival, D. Knottenbelt, 2011 .

Chronic equine wounds: what is the role of infection and biofilms?.

P. Clegg, S. Percival, D. Knottenbelt, 2010, Wounds : a compendium of clinical research and practice.

Letter to the Editor: Equine Veterinary Journal's antimicrobial stewardship policy.

P. Clegg, M. Bowen, C. Marr, 2016, Equine veterinary journal.

Equine welfare: Risk of horses falling in the Grand National

P. Clegg, C. Proudman, Peter Clegg, 2004, Nature.

Differential regulation of gelatinases by transforming growth factor beta-1 in normal equine chondrocytes.

P. Clegg, S. Carter, C. Thompson, 2001, Osteoarthritis and cartilage.

Investigating the efficacy of articular medications in the horse: the science behind clinical practices.

P. Clegg, 2010, Equine veterinary journal.

Owners’ perceptions of quality of life in geriatric horses: a cross-sectional study

G. Pinchbeck, P. Clegg, C. McGowan, 2011, Animal Welfare.

Stem cell-based therapies for bone repair.

P. Clegg, M. Stewart, P. Milner, 2011, The Veterinary clinics of North America. Equine practice.

Repair or destruction: optimising therapies for joint diseases.

P. Clegg, 2012, Equine Veterinary Journal.

Biomarkers for equine joint injury and osteoarthritis

M. Karsdal, C. Kawcak, L. Lohmander, 2018, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

Complete and partial hoof wall resection for keratoma removal: post operative complications and final outcome in 26 horses (1994-2004).

P. Clegg, E. Singer, I. Hughes, 2010, Equine veterinary journal.

Drugs used to treat osteoarthritis in the horse

P. Clegg, T. Booth, 2000, In Practice.

MicroRNA Signatures in Cartilage Ageing and Osteoarthritis

Yongxiang Fang, P. Clegg, M. Peffers, 2023, Biomedicines.

Postnatal mechanical loading drives adaptation of tissues primarily through modulation of the non-collagenous matrix

H. Birch, P. Clegg, H. Screen, 2020, bioRxiv.

Measurement of cartilage oligomeric matrix protein (COMP) in normal and diseased equine synovial fluids.

P. Clegg, S. Carter, S D Carter, 2001, Osteoarthritis and cartilage.

Fragmentation with Age-and Injury-specific Matrix Changes in Tendon Matrix Composition , Proteomic Analysis Reveals Age-related Genomics and Proteomics

P. Clegg, H. Screen, M. Peffers, 2014 .

Transcriptomic signatures in cartilage ageing

P. Clegg, M. Peffers, Xuan Liu, 2013, Arthritis Research & Therapy.

Collagen (I) homotrimer potentiates the osteogenesis imperfecta (oim) mutant allele and reduces survival in male mice

R. Akhtar, P. Clegg, George Bou-Gharios, 2020, bioRxiv.

Mouse microRNA signatures in joint ageing and post-traumatic osteoarthritis

Yongxiang Fang, P. Clegg, M. Peffers, 2021, Osteoarthritis and cartilage open.

Treatment of a coxofemoral luxation secondary to upward patella fixation in a Shetland pony

P. Clegg, R. Butson, 2005 .

Science in brief: recent advances into understanding tendon function and injury risk.

Ewa M. Spiesz, P. Clegg, H. Screen, 2015, Equine veterinary journal.

Is it just joint inflammation or is it septic? The nagging worry!

P. Clegg, 2010 .

Clinical insights: Recent developments in equine articular disease (2016-2018).

P. Clegg, 2018, Equine veterinary journal.

UKRI MRC National Musculoskeletal Ageing Network: strategic prioritisation to increase healthy lifespan and minimise physical frailty

E. McCloskey, C. Gregson, K. Ward, 2022, Archives of Osteoporosis.

Gene expression in human chondrocytes in late osteoarthritis is changed in both fibrillated and intact cartilage without evidence of generalised chondrocyte hypertrophy

C. Brew, T. Hardingham, P. Clegg, 2008, Annals of the rheumatic diseases.

The role of polyphosphates in the sequestration of matrix metalloproteinases

P. Clegg, S. Percival, C. Cochrane, 2015, International wound journal.

CT-guided injection technique into intervertebral discs in the ovine lumbar spine

J. Vandeweerd, P. Clegg, N. Kirschvink, 2013, European Spine Journal.

Risk factors for fatal lateral condylar fracture of the third metacarpus/metatarsus in UK racing.

T D H Parkin, P. Clegg, K. Morgan, 2010, Equine veterinary journal.

Race- and course-level risk factors for fatal distal limb fracture in racing Thoroughbreds.

T D H Parkin, P. Clegg, K. Morgan, 2010, Equine veterinary journal.

Fascicles from energy-storing tendons show an age-specific response to cyclic fatigue loading

Hazel R C Screen, Helen L Birch, H. Birch, 2014, Journal of The Royal Society Interface.

Isothiocyanates are detected in human synovial fluid following broccoli consumption and can affect the tissues of the knee joint

R. Mithen, M. Traka, S. Donell, 2017, Scientific Reports.

Horse–, training– and race–level risk factors for palmar/plantar osteochondral disease in the racing Thoroughbred

A. Boyde, G. Pinchbeck, P. Clegg, 2013, Equine veterinary journal.

Horse-level risk factors for fatal distal limb fracture in racing Thoroughbreds in the UK.

T D H Parkin, P. Clegg, K. Morgan, 2010, Equine veterinary journal.

Distribution of purinergic P2X receptors in the equine digit, cervical spinal cord and dorsal root ganglia

P. Clegg, J. M. Senior, S. Carter, 2013, Purinergic Signalling.

Epigenetic mechanisms in Tendon Ageing

P. Clegg, M. Peffers, K. Goljanek-Whysall, 2020, British medical bulletin.

Heterogeneity of proteome dynamics between connective tissue phases of adult tendon

P. Ping, D. Simpson, A. Pitsillides, 2020, bioRxiv.

Risk factors and sources of variation in horse falls in steeplechase racing in the UK.

J. Wood, G. Pinchbeck, P. Clegg, 2002, Preventive veterinary medicine.

SOX9 transduction of a human chondrocytic cell line identifies novel genes regulated in primary human chondrocytes and in osteoarthritis

C. Brew, T. Hardingham, P. Clegg, 2007, Arthritis research & therapy.

Cross-species gene modules emerge from a systems biology approach to osteoarthritis

P. Clegg, A. Mueller, S. Tew, 2017, npj Systems Biology and Applications.

Case-control investigation of the factors affecting the risk of horses falling during steeplechase racing in the UK

G. Pinchbeck, P. Clegg, N. French, 2004, Veterinary Record.

Comparison between chaotropic and detergent‐based sample preparation workflow in tendon for mass spectrometry analysis

P. Clegg, E. Comerford, D. Zamboulis, 2017, Proteomics.

Antibiotic Resistance and Chromosomal Variation in Equine Faecal Salmonella spp.

N. Williams, Mohamed O Ahmed, P. Clegg, 2012 .

Tendon Physiology and Mechanical Behavior

H. Birch, P. Clegg, H. Screen, 2015 .

Collagen (I) homotrimer does not cause bone fragility but potentiates the osteogenesis imperfecta (oim) mutant allele

R. Akhtar, P. Clegg, George Bou-Gharios, 2020 .

Capacity for sliding between tendon fascicles decreases with ageing in injury prone equine tendons: a possible mechanism for age-related tendinopathy?

H. Birch, P. Clegg, H. Screen, 2013, European cells & materials.

Effect of fatigue loading on structure and functional behaviour of fascicles from energy-storing tendons.

H. Birch, P. Clegg, H. Screen, 2014, Acta Biomaterialia.

response to cyclic fatigue loading Fascicles from energy-storing tendons show an age-specific

H. Birch, P. Clegg, H. Screen, 2014 .

Tendon overload results in alterations in cell shape and increased markers of inflammation and matrix degradation

H. Birch, P. Clegg, H. Screen, 2015, Scandinavian journal of medicine & science in sports.

Preparation and Culture of Myogenic Precursor Cells/Primary Myoblasts from Skeletal Muscle of Adult and Aged Humans

P. Clegg, K. Goljanek-Whysall, Ana Soriano-Arroquia, 2017, Journal of visualized experiments : JoVE.

Use of computed tomography in standing position to identify guidelines for screw insertion in the distal phalanx of horses: an ex vivo study.

J. Vandeweerd, F. Desbrosse, P. Clegg, 2009, Veterinary surgery : VS.

Transcriptomic signatures in cartilage ageing

P. Clegg, M. Peffers, Xuan Liu, 2013 .

Fascicles and the interfascicular matrix show decreased fatigue life with ageing in energy storing tendons☆

H. Birch, P. Clegg, H. Screen, 2017, Acta biomaterialia.

Therapeutic Potential of Dental Pulp Stem Cells and Leukocyte- and Platelet-Rich Fibrin for Osteoarthritis

J. Vandeweerd, P. Clegg, P. Gervois, 2020, Cells.

Assessment of the use of RNA quality metrics for the screening of articular cartilage specimens from clinically normal dogs and dogs with osteoarthritis.

W. Ollier, P. Clegg, J. Innes, 2006, American journal of veterinary research.

Assessment of the use of RNA quality metrics for the screening of normal and pathological canine articular cartilage samples.

P. Clegg, J. Innes, 2006 .

Avulsion of the proximal digital annular ligament in five hindlimbs

E. O'Brien, P. Clegg, R. Smith, 2018 .

Muscle disorders111. The impact of fatigue in patients with idiopathic inflammatory myopathy: a mixed method study

R. Moots, P. Salkovskis, Yulia Goryachev, 2012 .

Interaction with macrophages attenuates equine fibroblast‐like synoviocyte ADAMTS5 (aggrecanase‐2) gene expression following inflammatory stimulation

J. Hunt, P. Clegg, J. Innes, 2018, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

Differential tissue specific, temporal and spatial expression patterns of the Aggrecan gene is modulated by independent enhancer elements

P. Clegg, George Bou-Gharios, A. Neal, 2018, Scientific Reports.

Expression of matrix metalloproteinases, their inhibitors, and lysyl oxidase in myocardial samples from dogs with end-stage systemic and cardiac diseases.

P. Clegg, S. Tew, J. Dukes-McEwan, 2013, American journal of veterinary research.

Cross-sectional study of antimicrobial-resistant bacteria in horses. Part 1: Prevalence of antimicrobial-resistant Escherichia coli and methicillin-resistant Staphylococcus aureus.

P. Diggle, G. Pinchbeck, N. Williams, 2012, Equine veterinary journal.

The synovial fluid proteome differentiates between septic and nonseptic articular pathologies

D. Simpson, P. Clegg, M. Peffers, 2019, Journal of proteomics.

Hyperosmolarity regulates SOX9 mRNA posttranscriptionally in human articular chondrocytes

T. Hardingham, Emma T. Lowe, P. Clegg, 2009, American Journal of Physiology - Cell Physiology.

Equine flexor tendon imaging part 1: Recent developments in ultrasonography, with focus on the superficial digital flexor tendon.

P. Clegg, T. Maddox, A. Ehrle, 2021, Veterinary journal.

Fascicles and the interfascicular matrix show adaptation for fatigue resistance in energy storing tendons

H. Birch, P. Clegg, H. Screen, 2016, Acta biomaterialia.

Myocardial cytokine expression in dogs with systemic and naturally occurring cardiac diseases.

P. Clegg, S. Tew, J. Dukes-McEwan, 2013, American journal of veterinary research.

Accuracy of diagnostic techniques used in investigation of stifle lameness in horses — 40 cases

P. Clegg, E. Singer, G. Pinchbeck, 2010 .

The interfascicular matrix enables fascicle sliding and recovery in tendon, and behaves more elastically in energy storing tendons

H. Birch, P. Clegg, H. Screen, 2015, Journal of the mechanical behavior of biomedical materials.

Matrix metalloproteinases 2 and 9 activity in bovine synovial fluids.

P. Clegg, S. Carter, A. Coughlan, 2000, Journal of veterinary medicine. A, Physiology, pathology, clinical medicine.