Xuemei Zhang

Xuemei Zhang, Yibing Yin, Yuqiang Zheng, 2019, Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research.

c‐Jun N‐terminal kinase and Akt signalling pathways regulating tumour necrosis factor‐α‐induced interleukin‐32 expression in human lung fibroblasts: implications in airway inflammation

Hong Wang, Yujuan He, Xuemei Zhang, 2015, Immunology.

Screening and Identification of DnaJ Interaction Proteins in Streptococcus pneumoniae

Hong Wang, Yujuan He, Xuemei Zhang, 2013, Current Microbiology.

The Role of Laminin α4 in Human Umbilical Vein Endothelial Cells and Pathological Mechanism of Preeclampsia

Xiaoqiu Xiao, N. Shan, H. Qi, 2015, Reproductive Sciences.

Detoxified pneumolysin derivative ΔA146Ply inhibits autophagy and induces apoptosis in acute myeloid leukemia cells by activating mTOR signaling

Xuemei Zhang, Yibing Yin, Hong Zhang, 2022, Experimental & Molecular Medicine.

Progranulin is preferentially expressed in patients with psoriasis vulgaris and protects mice from psoriasis‐like skin inflammation

Xuemei Zhang, Yibing Yin, Aijun Chen, 2015, Immunology.

Screening and identification of ClpE interaction proteins in Streptococcus pneumoniae by a bacterial two-hybrid system and co-immunoprecipitation

Hong Wang, Yujuan He, Xuemei Zhang, 2013, Journal of Microbiology.

Engineering detoxified pneumococcal pneumolysin derivative ΔA146PLY for self-biomineralization of calcium phosphate: Assessment of their protective efficacy in murine infection models.

Xuemei Zhang, Yibing Yin, Wenchun Xu, 2018, Biomaterials.

PLY for self-biomineralization of calcium phosphate : Assessment of their protective ef fi cacy in murine infection models

Xuemei Zhang, Yibing Yin, Wenchun Xu, 2017 .

Streptococcus pneumoniae aminopeptidase N regulates dendritic cells that attenuates type‐2 airway inflammation in murine allergic asthma

Hong Wang, Jian Wang, Xuemei Zhang, 2020, British journal of pharmacology.

Protection against pneumococcal infection elicited by immunization with glutamyl tRNA synthetase, polyamine transport protein D and sortase A.

Hong Wang, Xuemei Zhang, Yibing Yin, 2012, Vaccine.

Enhanced protection against pneumococcal infection elicited by immunization with the combination of PspA, PspC, and ClpP.

Beizhong Liu, Xuemei Zhang, Yibing Yin, 2007, Vaccine.

DnaJ (hsp40) of Streptococcus pneumoniae is involved in bacterial virulence and elicits a strong natural immune reaction via PI3K/JNK

Jingjing Cui, Hong Wang, Jian Wang, 2017, Molecular immunology.

Streptococcus pneumoniae Endopeptidase O (PepO) Elicits a Strong Innate Immune Response in Mice via TLR2 and TLR4 Signaling Pathways

Yujuan He, Xuemei Zhang, Yibing Yin, 2016, Front. Cell. Infect. Microbiol..

GHIP in Streptococcus pneumoniae is involved in antibacterial resistance and elicits a strong innate immune response through TLR2 and JNK/p38MAPK

Hong Wang, Jingjing Cui, Jian Wang, 2014, The FEBS journal.

Inactivation of Transcriptional Regulator FabT Influences Colony Phase Variation of Streptococcus pneumoniae

Xuemei Zhang, Yibing Yin, Yuqiang Zheng, 2021, mBio.

Mucosal Immunization with Recombinant Fusion Protein DnaJ-ΔA146Ply Enhances Cross-Protective Immunity against Streptococcus pneumoniae Infection in Mice via Interleukin 17A

Hong Wang, Xuemei Zhang, Yibing Yin, 2014, Infection and Immunity.

Immunization with a ZmpB-Based Protein Vaccine Could Protect against Pneumococcal Diseases in Mice

Hong Wang, Yujuan He, Xuemei Zhang, 2010, Infection and Immunity.

Neonatal rhesus monkey is a potential animal model for studying pathogenesis of EV71 infection.

Hongling Zhao, Xuemei Zhang, Ying Zhang, 2011, Virology.

Type I IFN expression is stimulated by cytosolic MtDNA released from pneumolysin‐damaged mitochondria via the STING signaling pathway in macrophages

Hong Wang, Jian Wang, Xuemei Zhang, 2019, The FEBS journal.

Interleukin 17A Promotes Pneumococcal Clearance by Recruiting Neutrophils and Inducing Apoptosis through a p38 Mitogen-Activated Protein Kinase-Dependent Mechanism in Acute Otitis Media

Yujuan He, Xuemei Zhang, Yibing Yin, 2014, Infection and Immunity.

IL-17A Promotes Pneumococcal Clearance by Recruiting

Yujuan He, Xuemei Zhang, Yibing Yin, 2014 .

Serotype-independent protection against pneumococcal infections elicited by intranasal immunization with ethanol-killed pneumococcal strain, SPY1

Xuemei Zhang, Yibing Yin, Xiuyu Xu, 2014, Journal of Microbiology.

CD4(+) T lymphocytes mediated protection against invasive pneumococcal infection induced by mucosal immunization with ClpP and CbpA.

Xuemei Zhang, Yibing Yin, Wenchun Xu, 2009, Vaccine.

Type I interferon induced by DNA of nontypeable Haemophilus influenza modulates inflammatory cytokine profile to promote susceptibility to this bacterium.

Hong Wang, Jian Wang, Xuemei Zhang, 2019, International immunopharmacology.

Interleukin-17A Aggravates Middle Ear Injury Induced by Streptococcus pneumoniae through the p38 Mitogen-Activated Protein Kinase Signaling Pathway

Wenbin Liu, Yujuan He, Xuemei Zhang, 2017, Infection and Immunity.

Streptococcus pneumoniae autolysin LytA inhibits ISG15 and ISGylation through decreasing bacterial DNA abnormally accumulated in the cytoplasm of macrophages.

Hong Wang, Xuemei Zhang, Sijia Cao, 2021, Molecular immunology.

TLR2 promotes macrophage recruitment and Streptococcus pneumoniae clearance during mouse otitis media

Yujuan He, Xuemei Zhang, Yibing Yin, 2016, Pediatric Research.

Decreased expression of Wiskott-Aldrich syndrome protein family verprolin-homologous protein 2 may be involved in the development of pre-eclampsia.

Xiaoqiu Xiao, H. Qi, Xuemei Zhang, 2014, Reproductive biomedicine online.

Mucosal Immunization with the Live Attenuated Vaccine SPY1 Induces Humoral and Th2-Th17-Regulatory T Cell Cellular Immunity and Protects against Pneumococcal Infection

Hong Wang, Xuemei Zhang, Yibing Yin, 2014, Infection and Immunity.

CpsR, a GntR family regulator, transcriptionally regulates capsular polysaccharide biosynthesis and governs bacterial virulence in Streptococcus pneumoniae

Xuemei Zhang, Yibing Yin, Yuqiang Zheng, 2016, Scientific Reports.

Pneumococcal LytR Protein Is Required for the Surface Attachment of Both Capsular Polysaccharide and Teichoic Acids: Essential for Pneumococcal Virulence

Xuemei Zhang, Yibing Yin, Zhaoche Shu, 2018, Front. Microbiol..

miR-29b Reverses T helper 1 cells/T helper 2 cells Imbalance and Alleviates Airway Eosinophils Recruitment in OVA-Induced Murine Asthma by Targeting Inducible Co-Stimulator

Yulan Qiu, Xuemei Zhang, Yibing Yin, 2019, International Archives of Allergy and Immunology.

MgaSpn is a negative regulator of capsule and phosphorylcholine biosynthesis and influences the virulence of Streptococcus pneumoniae D39

Xuemei Zhang, Yibing Yin, Yuqiang Zheng, 2021, Virulence.

Pneumococcal wall teichoic acid is required for the pathogenesis of Streptococcus pneumoniae in murine models

Xuemei Zhang, Yibing Yin, Wenchun Xu, 2015, Journal of Microbiology.

Immunoprotection elicited by an enterovirus type 71 experimental inactivated vaccine in mice and rhesus monkeys.

Hongling Zhao, Xuemei Zhang, Yan Liang, 2011, Vaccine.

SP0454, a putative threonine dehydratase, is required for pneumococcal virulence in mice

Hong Wang, Xuemei Zhang, Wenchun Xu, 2012, Journal of Microbiology.

Mucosal immunization with caseinolytic protease X elicited cross-protective immunity against pneumococcal infection in mice

Hong Wang, Xuemei Zhang, Yibing Yin, 2012, Experimental biology and medicine.

IL-4 plays an essential role in DnaJ-ΔA146Ply-mediated immunoprotection against Streptococcus pneumoniae in mice.

Xuemei Zhang, Yibing Yin, Wenchun Xu, 2022, Molecular immunology.

spd1672, a novel in vivo-induced gene, affects inflammatory response in a murine model of Streptococcus pneumoniae infection.

Jingjing Cui, Hong Wang, Xuemei Zhang, 2018, Canadian journal of microbiology.

IL-27 Activates Human Trophoblasts to Express IP-10 and IL-6: Implications in the Immunopathophysiology of Preeclampsia

Xiaoqiu Xiao, N. Shan, H. Qi, 2014, Mediators of inflammation.

Mast cell degranulation impairs pneumococcus clearance in mice via IL-6 dependent and TNF-α independent mechanisms

Yulan Qiu, Yujuan He, Xuemei Zhang, 2019, The World Allergy Organization journal.

Cytosolic MtDNA Released from Pneumolysin-Damaged Mitochondria Triggers IFN-β Production in Epithelial Cells.

Hong Wang, Xuemei Zhang, Yibing Yin, 2020, Canadian journal of microbiology.

Novel Therapeutic Targeting of CCL3-CCR4 Axis Mediated Apoptotic Intesitnal Injury in Necrotizing Enterocolitis

Xuemei Zhang, Yibing Yin, Jufang Cao, 2022, Frontiers in Immunology.

Progesterone and nifedipine for maintenance tocolysis after arrested preterm labor: A systematic review and meta-analysis of randomized controlled trial.

Xuemei Zhang, Xin Luo, H. Qi, 2016, Taiwanese journal of obstetrics & gynecology.

Il-27 Enhances Innate Immunity of Human Pulmonary Fibroblasts and Epithelial Cells through Upregulation of Tlr4 Expression Running Title: Tlr4 Expression in Lung Tissue Cells by Il-27

Hong Wang, Xuemei Zhang, Yibing Yin, 2022 .

Molecular mechanisms of the secretion of cytokines and chemokines from human monocytes activated by pneumococcal surface protein A (PspA): Roles of mitogen-activated protein kinases and NF-kappaB

Xuemei Zhang, Yibing Yin, Wenchun Xu, 2010, Microbial Pathogenesis.

rM2e-ΔPly protein immunization induces protection against influenza viruses and its co-infection with Streptococcus pneumoniae in mice.

Xuemei Zhang, Yibing Yin, Lian Li, 2022, Molecular immunology.

Pneumococcal ClpP modulates the maturation and activation of human dendritic cells: implications for pneumococcal infections

Xuemei Zhang, Yibing Yin, Liping Zhang, 2013, Journal of leukocyte biology.

Heterologous prime-boost immunization with live SPY1 and DnaJ protein of Streptococcus pneumoniae induces strong Th1 and Th17 cellular immune responses in mice

Xinyuan Zhang, Hong Wang, Yulan Qiu, 2017, Journal of Microbiology.

The critical role of myeloperoxidase in Streptococcus pneumoniae clearance and tissue damage during mouse acute otitis media

Yujuan He, Xuemei Zhang, Yibing Yin, 2017, Innate immunity.

IL-6 Prevents Lung Macrophage Death and Lung Inflammation Injury by Inhibiting GSDME- and GSDMD-Mediated Pyroptosis during Pneumococcal Pneumosepsis

Xuemei Zhang, Yibing Yin, Wenchun Xu, 2022, Microbiology spectrum.

Interleukin 4 Deficiency Reverses Development of Secondary Pseudomonas aeruginosa Pneumonia During Sepsis-Associated Immunosuppression.

Hong Wang, Xuemei Zhang, Yibing Yin, 2015, The Journal of infectious diseases.

Apoptosis induced by pneumolysin in human endothelial cells involves mitogen-activated protein kinase phosphorylation.

Hong Wang, Yujuan He, Xuemei Zhang, 2012, International journal of molecular medicine.

Mitochondrial DNA Leakage Caused by Streptococcus pneumoniae Hydrogen Peroxide Promotes Type I IFN Expression in Lung Cells

Hong Wang, Xuemei Zhang, Wenchun Xu, 2019, Front. Microbiol..

Compound 48/80 acts as a potent mucosal adjuvant for vaccination against Streptococcus pneumoniae infection in young mice.

Yingying Wu, Hong Wang, Xuemei Zhang, 2015, Vaccine.

Progranulin Decreases Susceptibility to Streptococcus pneumoniae in Influenza and Protects against Lethal Coinfection

Hong Wang, Xuemei Zhang, Yibing Yin, 2019, The Journal of Immunology.

Purified Streptococcus pneumoniae Endopeptidase O (PepO) Enhances Particle Uptake by Macrophages in a Toll-Like Receptor 2- and miR-155-Dependent Manner

Hong Wang, Xuemei Zhang, Yibing Yin, 2017, Infection and Immunity.

Pneumococcal wall teichoic acid is required for the pathogenesis of Streptococcus pneumoniae in murine models

Xuemei Zhang, Yibing Yin, Wenchun Xu, 2015, Journal of Microbiology.

Excessive autophagy induces the failure of trophoblast invasion and vasculature: possible relevance to the pathogenesis of preeclampsia

P. Baker, Xuemei Zhang, Hua Zhang, 2015, Journal of hypertension.

IL-33 synergistically promotes the proliferation of lung cancer cells in vitro by inducing antibacterial peptide LL-37 and proinflammatory cytokines in macrophages.

Hong Wang, Xuemei Zhang, Hongyi Liao, 2020, Immunobiology.

Screening and Identification of DnaJ Interaction Proteins in Streptococcus pneumoniae

Hong Wang, Yujuan He, Xuemei Zhang, 2013, Current Microbiology.

CD5L attenuates allergic airway inflammation by expanding CD11chigh alveolar macrophages and inhibiting NLRP3 inflammasome activation via HDAC2

Xuemei Zhang, Yibing Yin, Wenchun Xu, 2022, Immunology.

IL-27 as a potential biomarker for distinguishing between necrotising enterocolitis and highly suspected early-onset food protein-induced enterocolitis syndrome with abdominal gas signs

Yuan Shi, Xuemei Zhang, Yibing Yin, 2021, EBioMedicine.

ComE, an Essential Response Regulator, Negatively Regulates the Expression of the Capsular Polysaccharide Locus and Attenuates the Bacterial Virulence in Streptococcus pneumoniae

Xuemei Zhang, Yibing Yin, Yuqiang Zheng, 2017, Front. Microbiol..

Muc5ac Production Inhibited by Decreased lncRNA H19 via PI3K/Akt/NF-kB in Asthma

Hong Wang, Xuemei Zhang, Wenchun Xu, 2021, Journal of asthma and allergy.

Subcutaneous immunization with Streptococcus pneumoniae GAPDH confers effective protection in mice via TLR2 and TLR4

Hong Wang, Yujuan He, Xuemei Zhang, 2017, Molecular immunology.

Streptococcus pneumoniae Endopeptidase O Promotes the Clearance of Staphylococcus aureus and Streptococcus pneumoniae via SH2 Domain-Containing Inositol Phosphatase 1-Mediated Complement Receptor 3 Upregulation

Xuemei Zhang, Yibing Yin, Wenchun Xu, 2020, Frontiers in Cellular and Infection Microbiology.

Apelin Promotes ECM Synthesis by Enhancing Autophagy Flux via TFEB in Human Degenerative NP Cells under Oxidative Stress

Xuemei Zhang, Wei Jiang, Pei Zhao, 2020, BioMed research international.

Apelin Promotes ECMSynthesis by EnhancingAutophagy Flux via TFEB in Human Degenerative NP Cells under Oxidative Stress

Xuemei Zhang, Wei Jiang, Pei Zhao, 2020 .

Combination of Detoxified Pneumolysin Derivative ΔA146Ply and Berbamine as a Treatment Approach for Breast Cancer

Hong Wang, Xuemei Zhang, Yibing Yin, 2020, Molecular therapy oncolytics.

Attenuated Streptococcus pneumoniae vaccine candidate SPY1 promotes dendritic cell activation and drives a Th1/Th17 response.

Jingjing Cui, Yingying Wu, Hong Wang, 2016, Immunology letters.

Serotype-independent protection against pneumococcal infections elicited by intranasal immunization with ethanol-killed pneumococcal strain, SPY1

Xuemei Zhang, Yibing Yin, Xiuyu Xu, 2014, Journal of Microbiology.

Discovery of novel inhibitors of Streptococcus pneumoniae based on the virtual screening with the homology-modeled structure of histidine kinase (VicK)

Weiliang Zhu, Xuemei Zhang, Yibing Yin, 2009, BMC Microbiology.

Immunization with a Combination of Three Pneumococcal Proteins Confers Additive and Broad Protection against Streptococcus pneumoniae Infections in Mice

Hong Wang, Yujuan He, Xuemei Zhang, 2009, Infection and Immunity.

Antibacterial effects of Traditional Chinese Medicine monomers against Streptococcus pneumoniae via inhibiting pneumococcal histidine kinase (VicK)

Xuemei Zhang, Wenchun Xu, Yusi Liu, 2015, Front. Microbiol..

LAMA5 promotes human umbilical vein endothelial cells migration, proliferation, and angiogenesis and is decreased in preeclampsia

H. Qi, Xuemei Zhang, Wei Jiang, 2018, The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians.

SCCmec-associated psm-mec mRNA promotes Staphylococcus epidermidis biofilm formation

Xuemei Zhang, Yibing Yin, Wen-fang Huang, 2016, Antonie van Leeuwenhoek.

SP0454, a putative threonine dehydratase, is required for pneumococcal virulence in mice

Hong Wang, Xuemei Zhang, Wenchun Xu, 2012, Journal of Microbiology.

Methotrexate-loaded PLGA nanobubbles for ultrasound imaging and Synergistic Targeted therapy of residual tumor during HIFU ablation.

Zhigang Wang, Yuanyi Zheng, Xiaoqiu Xiao, 2014, Biomaterials.

Interleukin‐4 protects mice against lethal influenza and Streptococcus pneumoniae co‐infected pneumonia

Hong Wang, Xuemei Zhang, Yibing Yin, 2021, Clinical and experimental immunology.

Immunization with DnaJ (hsp40) could elicit protection against nasopharyngeal colonization and invasive infection caused by different strains of Streptococcus pneumoniae.

Yibing Yin, Yujuan He, Hong Wang, 2011, Vaccine.

comCDE (Competence) Operon Is Regulated by CcpA in Streptococcus pneumoniae D39

Xuemei Zhang, Yibing Yin, Yuqiang Zheng, 2023, Microbiology spectrum.