Wenchun Xu

发表

Streptococcus pneumoniae Attenuated Strain SPY1 with an Artificial Mineral Shell Induces Humoral and Th17 Cellular Immunity and Protects Mice against Pneumococcal Infection

Xinyuan Zhang, Jingjing Cui, Yingying Wu, 2018, Front. Immunol..

Nontypeable Haemophilus influenzae DNA stimulates type I interferon expression via STING signaling pathway.

Jingjing Cui, Hong Wang, Xuemei Zhang, 2018, Biochimica et biophysica acta. Molecular cell research.

Oleanolic Acid Diminishes Liquid Fructose-Induced Fatty Liver in Rats: Role of Modulation of Hepatic Sterol Regulatory Element-Binding Protein-1c-Mediated Expression of Genes Responsible for De Novo Fatty Acid Synthesis

Y. Li, Yifan Yang, Yuhao Li, 2013, Evidence-based complementary and alternative medicine : eCAM.

Pneumococcal DnaJ modulates dendritic cell-mediated Th1 and Th17 immune responses through Toll-like receptor 4 signaling pathway.

Jingjing Cui, Yingying Wu, Yujuan He, 2017, Immunobiology.

Streptococcus pneumoniae is a Gram-positive pathogen with high morbidity and mortality globally but some of its patho-

Hong Wang, Xuemei Zhang, Wenchun Xu, 2020 .

Streptococcus pneumoniae aminopeptidase N contributes to bacterial virulence and elicits a strong innate immune response through MAPK and PI3K/AKT signaling

Hong Wang, Xuemei Zhang, Wenchun Xu, 2020, Journal of Microbiology.

A Novel Protein, RafX, Is Important for Common Cell Wall Polysaccharide Biosynthesis in Streptococcus pneumoniae: Implications for Bacterial Virulence

Xuemei Zhang, Yibing Yin, Wenchun Xu, 2014, Journal of bacteriology.

[Histidine kinase (YycG) protein of Streptococcus pneumoniae: homology modeling and analysis].

Xiaomin Luo, Weiliang Zhu, Hong Wang, 2009, Sheng wu gong cheng xue bao = Chinese journal of biotechnology.

Mucosal immunization with purified ClpP could elicit protective efficacy against pneumococcal pneumonia and sepsis in mice.

Xuemei Zhang, Yibing Yin, Wenchun Xu, 2008, Microbes and infection.

Establishment of a rapid and sensitive method based on recombinase polymerase amplification to detect mts90, a new molecular target of Mycobacterium tuberculosis

Xinyuan Zhang, Yulan Qiu, Yunjun Mo, 2017 .

An efficient alternative marker for specific identification of Mycobacterium tuberculosis

Hong Wang, Yujuan He, Xuemei Zhang, 2014, World Journal of Microbiology and Biotechnology.

c‐Jun N‐terminal kinase and Akt signalling pathways regulating tumour necrosis factor‐α‐induced interleukin‐32 expression in human lung fibroblasts: implications in airway inflammation

Hong Wang, Yujuan He, Xuemei Zhang, 2015, Immunology.

Screening and Identification of DnaJ Interaction Proteins in Streptococcus pneumoniae

Hong Wang, Yujuan He, Xuemei Zhang, 2013, Current Microbiology.

Screening and identification of ClpE interaction proteins in Streptococcus pneumoniae by a bacterial two-hybrid system and co-immunoprecipitation

Hong Wang, Yujuan He, Xuemei Zhang, 2013, Journal of Microbiology.

Engineering detoxified pneumococcal pneumolysin derivative ΔA146PLY for self-biomineralization of calcium phosphate: Assessment of their protective efficacy in murine infection models.

Xuemei Zhang, Yibing Yin, Wenchun Xu, 2018, Biomaterials.

PLY for self-biomineralization of calcium phosphate : Assessment of their protective ef fi cacy in murine infection models

Xuemei Zhang, Yibing Yin, Wenchun Xu, 2017 .

Streptococcus pneumoniae aminopeptidase N regulates dendritic cells that attenuates type‐2 airway inflammation in murine allergic asthma

Hong Wang, Jian Wang, Xuemei Zhang, 2020, British journal of pharmacology.

Protection against pneumococcal infection elicited by immunization with glutamyl tRNA synthetase, polyamine transport protein D and sortase A.

Hong Wang, Xuemei Zhang, Yibing Yin, 2012, Vaccine.

A purification method for tag-free human cystatin C recombinant protein expressed in Escherichia coli

Wenchun Xu, Te Chen, 2017, Preparative biochemistry & biotechnology.

In vivo characterization of Streptococcus pneumoniae genes involved in the pathogenesis of meningitis by differential fluorescence induction.

Hong Wang, Wenchun Xu, Xue-Mei Zhang, 2010, Saudi medical journal.

Enhanced protection against pneumococcal infection elicited by immunization with the combination of PspA, PspC, and ClpP.

Beizhong Liu, Xuemei Zhang, Yibing Yin, 2007, Vaccine.

DnaJ (hsp40) of Streptococcus pneumoniae is involved in bacterial virulence and elicits a strong natural immune reaction via PI3K/JNK

Jingjing Cui, Hong Wang, Jian Wang, 2017, Molecular immunology.

Streptococcus pneumoniae Endopeptidase O (PepO) Elicits a Strong Innate Immune Response in Mice via TLR2 and TLR4 Signaling Pathways

Yujuan He, Xuemei Zhang, Yibing Yin, 2016, Front. Cell. Infect. Microbiol..

GHIP in Streptococcus pneumoniae is involved in antibacterial resistance and elicits a strong innate immune response through TLR2 and JNK/p38MAPK

Hong Wang, Jingjing Cui, Jian Wang, 2014, The FEBS journal.

Immunization with a ZmpB-Based Protein Vaccine Could Protect against Pneumococcal Diseases in Mice

Hong Wang, Yujuan He, Xuemei Zhang, 2010, Infection and Immunity.

Type I IFN expression is stimulated by cytosolic MtDNA released from pneumolysin‐damaged mitochondria via the STING signaling pathway in macrophages

Hong Wang, Jian Wang, Xuemei Zhang, 2019, The FEBS journal.

Synergy of IL-27 and TNF-α in regulating CXCL10 expression in lung fibroblasts.

Hong Wang, Yujuan He, Yibing Yin, 2013, American journal of respiratory cell and molecular biology.

CD4(+) T lymphocytes mediated protection against invasive pneumococcal infection induced by mucosal immunization with ClpP and CbpA.

Xuemei Zhang, Yibing Yin, Wenchun Xu, 2009, Vaccine.

Innate Anti-microbial and Anti-chemotaxis Properties of Progranulin in an Acute Otitis Media Mouse Model

Yujuan He, Yibing Yin, Wenchun Xu, 2018, Front. Immunol..

Type I interferon induced by DNA of nontypeable Haemophilus influenza modulates inflammatory cytokine profile to promote susceptibility to this bacterium.

Hong Wang, Jian Wang, Xuemei Zhang, 2019, International immunopharmacology.

Interleukin-17A Aggravates Middle Ear Injury Induced by Streptococcus pneumoniae through the p38 Mitogen-Activated Protein Kinase Signaling Pathway

Wenbin Liu, Yujuan He, Xuemei Zhang, 2017, Infection and Immunity.

TLR2 promotes macrophage recruitment and Streptococcus pneumoniae clearance during mouse otitis media

Yujuan He, Xuemei Zhang, Yibing Yin, 2016, Pediatric Research.

Mucosal Immunization with the Live Attenuated Vaccine SPY1 Induces Humoral and Th2-Th17-Regulatory T Cell Cellular Immunity and Protects against Pneumococcal Infection

Hong Wang, Xuemei Zhang, Yibing Yin, 2014, Infection and Immunity.

miR-29b Reverses T helper 1 cells/T helper 2 cells Imbalance and Alleviates Airway Eosinophils Recruitment in OVA-Induced Murine Asthma by Targeting Inducible Co-Stimulator

Yulan Qiu, Xuemei Zhang, Yibing Yin, 2019, International Archives of Allergy and Immunology.

Pneumococcal wall teichoic acid is required for the pathogenesis of Streptococcus pneumoniae in murine models

Xuemei Zhang, Yibing Yin, Wenchun Xu, 2015, Journal of Microbiology.

SP0454, a putative threonine dehydratase, is required for pneumococcal virulence in mice

Hong Wang, Xuemei Zhang, Wenchun Xu, 2012, Journal of Microbiology.

Mucosal immunization with caseinolytic protease X elicited cross-protective immunity against pneumococcal infection in mice

Hong Wang, Xuemei Zhang, Yibing Yin, 2012, Experimental biology and medicine.

IL-4 plays an essential role in DnaJ-ΔA146Ply-mediated immunoprotection against Streptococcus pneumoniae in mice.

Xuemei Zhang, Yibing Yin, Wenchun Xu, 2022, Molecular immunology.

Contribution of ClpE to virulence of Streptococcus pneumoniae.

Hong Wang, Wenchun Xu, Xue-Mei Zhang, 2009, Canadian journal of microbiology.

spd1672, a novel in vivo-induced gene, affects inflammatory response in a murine model of Streptococcus pneumoniae infection.

Jingjing Cui, Hong Wang, Xuemei Zhang, 2018, Canadian journal of microbiology.

Mast cell degranulation impairs pneumococcus clearance in mice via IL-6 dependent and TNF-α independent mechanisms

Yulan Qiu, Yujuan He, Xuemei Zhang, 2019, The World Allergy Organization journal.

Cytosolic MtDNA Released from Pneumolysin-Damaged Mitochondria Triggers IFN-β Production in Epithelial Cells.

Hong Wang, Xuemei Zhang, Yibing Yin, 2020, Canadian journal of microbiology.

Molecular mechanisms of the secretion of cytokines and chemokines from human monocytes activated by pneumococcal surface protein A (PspA): Roles of mitogen-activated protein kinases and NF-kappaB

Xuemei Zhang, Yibing Yin, Wenchun Xu, 2010, Microbial Pathogenesis.

Heterologous prime-boost immunization with live SPY1 and DnaJ protein of Streptococcus pneumoniae induces strong Th1 and Th17 cellular immune responses in mice

Xinyuan Zhang, Hong Wang, Yulan Qiu, 2017, Journal of Microbiology.

The critical role of myeloperoxidase in Streptococcus pneumoniae clearance and tissue damage during mouse acute otitis media

Yujuan He, Xuemei Zhang, Yibing Yin, 2017, Innate immunity.

IL-6 Prevents Lung Macrophage Death and Lung Inflammation Injury by Inhibiting GSDME- and GSDMD-Mediated Pyroptosis during Pneumococcal Pneumosepsis

Xuemei Zhang, Yibing Yin, Wenchun Xu, 2022, Microbiology spectrum.

Interleukin 4 Deficiency Reverses Development of Secondary Pseudomonas aeruginosa Pneumonia During Sepsis-Associated Immunosuppression.

Hong Wang, Xuemei Zhang, Yibing Yin, 2015, The Journal of infectious diseases.

Apoptosis induced by pneumolysin in human endothelial cells involves mitogen-activated protein kinase phosphorylation.

Hong Wang, Yujuan He, Xuemei Zhang, 2012, International journal of molecular medicine.

Mitochondrial DNA Leakage Caused by Streptococcus pneumoniae Hydrogen Peroxide Promotes Type I IFN Expression in Lung Cells

Hong Wang, Xuemei Zhang, Wenchun Xu, 2019, Front. Microbiol..

Compound 48/80 acts as a potent mucosal adjuvant for vaccination against Streptococcus pneumoniae infection in young mice.

Yingying Wu, Hong Wang, Xuemei Zhang, 2015, Vaccine.

Pneumococcal wall teichoic acid is required for the pathogenesis of Streptococcus pneumoniae in murine models

Xuemei Zhang, Yibing Yin, Wenchun Xu, 2015, Journal of Microbiology.

Screening and Identification of DnaJ Interaction Proteins in Streptococcus pneumoniae

Hong Wang, Yujuan He, Xuemei Zhang, 2013, Current Microbiology.

CD5L attenuates allergic airway inflammation by expanding CD11chigh alveolar macrophages and inhibiting NLRP3 inflammasome activation via HDAC2

Xuemei Zhang, Yibing Yin, Wenchun Xu, 2022, Immunology.

IL-27 as a potential biomarker for distinguishing between necrotising enterocolitis and highly suspected early-onset food protein-induced enterocolitis syndrome with abdominal gas signs

Yuan Shi, Xuemei Zhang, Yibing Yin, 2021, EBioMedicine.

Muc5ac Production Inhibited by Decreased lncRNA H19 via PI3K/Akt/NF-kB in Asthma

Hong Wang, Xuemei Zhang, Wenchun Xu, 2021, Journal of asthma and allergy.

Subcutaneous immunization with Streptococcus pneumoniae GAPDH confers effective protection in mice via TLR2 and TLR4

Hong Wang, Yujuan He, Xuemei Zhang, 2017, Molecular immunology.

Streptococcus pneumoniae Endopeptidase O Promotes the Clearance of Staphylococcus aureus and Streptococcus pneumoniae via SH2 Domain-Containing Inositol Phosphatase 1-Mediated Complement Receptor 3 Upregulation

Xuemei Zhang, Yibing Yin, Wenchun Xu, 2020, Frontiers in Cellular and Infection Microbiology.

Combination of Detoxified Pneumolysin Derivative ΔA146Ply and Berbamine as a Treatment Approach for Breast Cancer

Hong Wang, Xuemei Zhang, Yibing Yin, 2020, Molecular therapy oncolytics.

Attenuated Streptococcus pneumoniae vaccine candidate SPY1 promotes dendritic cell activation and drives a Th1/Th17 response.

Jingjing Cui, Yingying Wu, Hong Wang, 2016, Immunology letters.

Immunization with a Combination of Three Pneumococcal Proteins Confers Additive and Broad Protection against Streptococcus pneumoniae Infections in Mice

Hong Wang, Yujuan He, Xuemei Zhang, 2009, Infection and Immunity.

Antibacterial effects of Traditional Chinese Medicine monomers against Streptococcus pneumoniae via inhibiting pneumococcal histidine kinase (VicK)

Xuemei Zhang, Wenchun Xu, Yusi Liu, 2015, Front. Microbiol..

SP0454, a putative threonine dehydratase, is required for pneumococcal virulence in mice

Hong Wang, Xuemei Zhang, Wenchun Xu, 2012, Journal of Microbiology.

Protein Kinase CK2 Promotes Proliferation, Abnormal Differentiation, and Proinflammatory Cytokine Production of Keratinocytes via Regulation of STAT3 and Akt Pathways in Psoriasis.

Wenchun Xu, Qian Li, Wenjie Huang, 2023, The American journal of pathology.

Interleukin‐4 protects mice against lethal influenza and Streptococcus pneumoniae co‐infected pneumonia

Hong Wang, Xuemei Zhang, Yibing Yin, 2021, Clinical and experimental immunology.

Progranulin deficiency suppresses allergic asthma and enhances efferocytosis via PPAR‐γ/MFG‐E8 regulation in macrophages

Hong Wang, Wenchun Xu, Shifei Yao, 2023, Immunity, inflammation and disease.

Immunization with DnaJ (hsp40) could elicit protection against nasopharyngeal colonization and invasive infection caused by different strains of Streptococcus pneumoniae.

Yibing Yin, Yujuan He, Hong Wang, 2011, Vaccine.