I. Uchegbu

Clive G. Wilson, I. Uchegbu, F. Koosha, 2003, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Low Molecular Weight Micelles

I. Uchegbu, 2013 .

Fast gelation of self-assembling peptide nanofibres triggered by electromagnetic radiation heating

A. Schätzlein, I. Uchegbu, M. Mazza, 2011 .

Unusual Enthalpy Driven Self Assembly at Room Temperature with Chitosan Amphiphiles

A. Schätzlein, I. Uchegbu, U. Odunze, 2019, Pharmaceutical nanotechnology.

Claw amphiphiles with a dendrimer core: nanoparticle stability and drug encapsulation are directly proportional to the number of digits.

X. Qu, I. Uchegbu, Xueliang Hou, 2013, Langmuir : the ACS journal of surfaces and colloids.

Pharmaceutical and biological characterisation of a doxorubicin-polymer conjugate (PK1) entrapped in sorbitan monostearate Span 60 niosomes

R. Duncan, I. Uchegbu, A. Florence, 1997 .

Hyaluronidase Coated Molecular Envelope Technology Nanoparticles Enhance Drug Absorption via the Subcutaneous Route

I. Uchegbu, A. Petkova, R. Soundararajan, 2020 .

The effect of processing variables on the physical characteristics of non-ionic surfactant vesicles (niosomes) formed from a hexadecyl diglycerol ether.

D. Craig, I. Uchegbu, A. Florence, 2000, International journal of pharmaceutics.

Polymer Based Gene Silencing: In Vitro Delivery of SiRNA.

A. Schätzlein, I. Uchegbu, M. Carlos, 2016, Methods in molecular biology.

Increased Efficacy of Oral Fixed-Dose Combination of Amphotericin B and AHCC® Natural Adjuvant against Aspergillosis

A. Schätzlein, I. Uchegbu, D. Serrano, 2019, Pharmaceutics.

Carbohydrate-based micelle clusters which enhance hydrophobic drug bioavailability by up to 1 order of magnitude.

Clive G. Wilson, A. Schätzlein, I. Uchegbu, 2006, Biomacromolecules.

Nanoparticulate peptide delivery exclusively to the brain produces tolerance free analgesia

A. Schätzlein, I. Uchegbu, J. Moger, 2018, Journal of controlled release : official journal of the Controlled Release Society.

Nanomedicines and nanodiagnostics come of age.

I. Uchegbu, Adeline Siew, 2013, Journal of pharmaceutical sciences.

Hydration forces as a tool for the optimization of core–shell nanoparticle vectors for cancer gene therapy

M. V. Lozano, M. J. Santander-Ortega, A. Schätzlein, 2012 .

Early Economic Evaluation of Diagnostic Technologies: Experiences of the NIHR Diagnostic Evidence Co-operatives

Yaling Yang, Peter Hall, Sara Graziadio, 2019, Medical decision making : an international journal of the Society for Medical Decision Making.

The evaluation of crown ether based niosomes as cation containing and cation sensitive drug delivery systems

I. Uchegbu, I. A. Darwish, 1997 .

Fundamentals of Pharmaceutical Nanoscience

Aikaterini Lalatsa, Andreas G. Schätzlein, Ijeoma F. Uchegbu, 2013, Springer New York.

Particulate levodopa nose-to-brain delivery targets dopamine to the brain with no plasma exposure.

A. Schätzlein, I. Uchegbu, I. Kubajewska, 2022, International journal of pharmaceutics.

Polyelectrolyte nanoparticles with high drug loading enhance the oral uptake of hydrophobic compounds.

L. Tetley, A. Schätzlein, A. Gray, 2006, Biomacromolecules.

Non-ionic surfactant based vesicles (niosomes) in drug delivery

Ijeoma F. Uchegbu, I. Uchegbu, S. P. Vyas, 1998 .

Polymers in Drug Delivery

Ijeoma F. Uchegbu, I. Uchegbu, 2004 .

The oral delivery of amphotericin B.

I. Uchegbu, D. Serrano, J. Torrado, 2013, Therapeutic delivery.

Dextran-pegylated microparticles for enhanced cellular uptake of hydrophobic drugs.

A. Schätzlein, I. Uchegbu, R. Cassano, 2013, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Polyhedral Non‐ionic Surfactant Vesicles

A. Schätzlein, I. Uchegbu, A. Florence, 1997, The Journal of pharmacy and pharmacology.

Non-ionic surfactant vesicles (niosomes): Physical and pharmaceutical chemistry

I. Uchegbu, A. Florence, 1995 .

LARGE DISK-SHAPED STRUCTURES (DISCOMES) IN NONIONIC SURFACTANT VESICLE TO MICELLE TRANSITIONS

J. Bouwstra, I. Uchegbu, A. Florence, 1992 .

Distribution, Metabolism and Tumoricidal Activity of Doxorubicin Administered in Sorbitan Monostearate (Span 60) Niosomes in the Mouse

Ijeoma F. Uchegbu, Alexander T. Florence, J. Double, 1995, Pharmaceutical Research.

Niosomes and Polymeric Chitosan Based Vesicles Bearing Transferrin and Glucose Ligands for Drug Targeting

L. Tetley, A. Schätzlein, A. Gray, 2000, Pharmaceutical Research.

Amphotericin B Formulations – The Possibility of Generic Competition

A. Schätzlein, I. Uchegbu, D. Serrano, 2013 .

Oral particle uptake and organ targeting drives the activity of amphotericin B nanoparticles.

A. Schätzlein, J. Guarro, I. Uchegbu, 2015, Molecular pharmaceutics.

A POLYMERIC AQUEOUS TACROLIMUS FORMULATION FOR TOPICAL OCULAR DELIVERY.

A. Schatzlein, I. Uchegbu, Moutaz Y. Badr, 2021, International journal of pharmaceutics.

Dendrimers in gene delivery B

A. Schätzlein, I. Uchegbu, C. Dufès, 2005 .

Amphotericin B Polymer Nanoparticles Show Efficacy against Candida Species Biofilms

P. Stapleton, A. Schatzlein, I. Uchegbu, 2022, Pathogens.

The release of model macromolecules may be controlled by the hydrophobicity of palmitoyl glycol chitosan hydrogels.

Clive G. Wilson, L. Tetley, A. Gray, 2002, Journal of controlled release : official journal of the Controlled Release Society.

Delivery of peptides to the blood and brain after oral uptake of quaternary ammonium palmitoyl glycol chitosan nanoparticles.

I. Uchegbu, A. Schätzlein, I. Uchegbu, 2012, Molecular pharmaceutics.

SARS-CoV-2 inhibition using a mucoadhesive, amphiphilic chitosan that may serve as an anti-viral nasal spray

A. Schätzlein, K. Pyrć, A. Milewska, 2021, Scientific Reports.

SARS-CoV-2 inhibition in human airway epithelial cells using a mucoadhesive, amphiphilic chitosan that may serve as an anti-viral nasal spray

A. Schätzlein, K. Pyrć, A. Milewska, 2020, bioRxiv.

A non-covalently cross-linked chitosan based hydrogel.

A. Gray, I. Uchegbu, I F Uchegbu, 1999, International journal of pharmaceutics.

Chitosan amphiphiles provide new drug delivery opportunities

A. Schätzlein, I. Uchegbu, Xueliang Hou, 2014 .

Gene and Ribonucleic Acid Therapy

A. Schätzlein, I. Uchegbu, J. Iemsam-arng, 2013 .

Dufès, Christine and Schätzlein, A.G. and Tetley, L. and Gray, A.I. and Watson, D.G. and Olivier, J.C. and Couet, W. and Uchegbu, I.F. (2000) Niosomes and polymeric chitosan based vesicles bearing transferrin

L. Tetley, A. Schätzlein, A. Gray, 2018 .

Enhanced oral absorption of hydrophobic and hydrophilic drugs using quaternary ammonium palmitoyl glycol chitosan nanoparticles.

Ijeoma Uchegbu, P. Gellert, A. Schatzlein, 2012, Molecular pharmaceutics.

The Topical Ocular Delivery of Rapamycin to Posterior Eye Tissues and the Suppression of Retinal Inflammatory Disease.

A. Schätzlein, M. Eskandarpour, I. Uchegbu, 2022, International journal of pharmaceutics.

Strategies to deliver peptide drugs to the brain.

A. Schatzlein, I. Uchegbu, A. Lalatsa, 2014, Molecular pharmaceutics.

Nanofiber-based delivery of therapeutic peptides to the brain.

Michael A. Briggs, A. Schätzlein, G. Parkinson, 2013, ACS nano.

Tissue-Engineering the Fibrous Pancreatic Tumour Stroma Capsule in 3D Tumouroids to Demonstrate Paclitaxel Response

M. Emberton, A. Schatzlein, I. Uchegbu, 2021, International journal of molecular sciences.

Polymers Used for the Delivery of Genes in Gene Therapy

A. Schätzlein, I. Uchegbu, P. Kan, 2006 .

Gene Transfer with Three Amphiphilic Glycol Chitosans—the Degree of Polymerisation is the Main Controller of Transfection Efficiency

L. Tetley, A. Schätzlein, A. Gray, 2004, Journal of drug targeting.

Nose to brain delivery in rats: Effect of surface charge of rhodamine B labeled nanocarriers on brain subregion localization.

M. Serapide, I. Uchegbu, R. Pellitteri, 2017, Colloids and surfaces. B, Biointerfaces.

Achieving highly efficient gene transfer to the bladder by increasing the molecular weight of polymer-based nanoparticles.

A. Schätzlein, Shanshan He, R. Weiss, 2021, Journal of controlled release : official journal of the Controlled Release Society.

13 Dendrimers in Drug and Gene Delivery

A. Schätzlein, I. Uchegbu, C. Dufès, 2006 .

A nano-enabled cancer-specific ITCH RNAi chemotherapy booster for pancreatic cancer.

M. J. Santander-Ortega, A. Schätzlein, I. Uchegbu, 2015, Nanomedicine : nanotechnology, biology, and medicine.

The Level of Hydrophobic Substitution and the Molecular Weight of Amphiphilic Poly-L-lysine-Based Polymers Strongly Affects Their Assembly into Polymeric Bilayer Vesicles.

L. Tetley, I. Uchegbu, Wei Wang, 2001, Journal of colloid and interface science.

Pharmaceutical nanotechnology: polymeric vesicles for drug and gene delivery

I. Uchegbu, 2006, Expert opinion on drug delivery.

Glucose-receptor MR imaging of tumors: study in mice with PEGylated paramagnetic niosomes.

A. Luciani, E. Kahn, G. Frija, 2004, Radiology.

Physical characterisation and long-term stability studies on quaternary ammonium palmitoyl glycol chitosan (GCPQ)--a new drug delivery polymer.

A. Schätzlein, S. Gaisford, I. Uchegbu, 2014, Journal of pharmaceutical sciences.

Quaternary ammonium palmitoyl glycol chitosan--a new polysoap for drug delivery.

A. Schätzlein, A. Gray, I. Uchegbu, 2001, International journal of pharmaceutics.

In vitro/in vivo characterisation of polyhedral niosomes.

D. Craig, I. Uchegbu, A. Florence, 1999, International journal of pharmaceutics.

Drug distribution and a pulmonary adverse effect of intraperitoneally administered doxorubicin niosomes in the mouse

J. Double, I. Uchegbu, A. Florence, 1994, Biopharmaceutics & drug disposition.

Lomustine Nanoparticles Enable Both Bone Marrow Sparing and High Brain Drug Levels – A Strategy for Brain Cancer Treatments

A. Schätzlein, R. Satchi‐Fainaro, F. Fisusi, 2016, Pharmaceutical Research.

The polyacrylic acid/modified chitosan capsules with tunable release of small hydrophobic probe and drug

V. Salnikov, I. Uchegbu, L. Zakharova, 2015 .

Polymeric Micelles as Pharmaceutical Carriers

I. Uchegbu, 2006 .

Imaging cortical vasculature with stimulated Raman scattering and two‐photon photothermal lensing microscopy

D. Begley, I. Uchegbu, J. Moger, 2012 .

Nose-to-Brain Delivery

A. Schätzlein, I. Uchegbu, Zian Wang, 2019, The Journal of Pharmacology and Experimental Therapeutics.

Polymeric Nanoparticles as Drug Carriers

I. Uchegbu, 2006 .

Anticancer Drug Delivery with Transferrin Targeted Polymeric Chitosan Vesicles

A. Schätzlein, W. Couet, I. Uchegbu, 2004, Pharmaceutical Research.

Poly(lactic-co-glycolic acid) Microspheres

I. Uchegbu, 2006 .

A Cost Analysis of Cardiac Magnetic Resonance Imaging in the Diagnostic Pathway of Patients Presenting With Unexplained Acute Myocardial Injury and Culprit-Free Coronary Angiography

S. Petersen, I. Uchegbu, S. Mohiddin, 2021, Frontiers in Cardiovascular Medicine.

Some aspects of the niosomal delivery of doxorubicin.

I. Uchegbu, 1994 .

Platinum(IV)-Loaded Degraded Glycol Chitosan as Efficient Platinum(IV) Drug Delivery Platform

A. Schätzlein, M. Jakupec, B. Keppler, 2023, Pharmaceutics.

Emulsions and Nanosuspensions for the Formulation of Poorly Soluble Drugs, Edited by R.H. Muller, S. Benita, B. Bohm, Medpharm Scientific Publishers, Stuttgart, 1998. ISBN 3-88763-069-6

I. Uchegbu, 2001 .

Dendrimer-Based Gene Delivery Systems: Administration Routes and In Vivo Evaluation

M. J Santander‐Ortega, I. F. Uchegbu, A. G. Schätzlein, 2012 .

Liposomes encapsulating polymeric chitosan based vesicles--a vesicle in vesicle system for drug delivery.

L. Tetley, I. Uchegbu, C. Dufès, 2000, International journal of pharmaceutics.

PEI-based vesicle-polymer hybrid gene delivery system with improved biocompatibility.

A. Schätzlein, I. Uchegbu, A. Brownlie, 2004, International journal of pharmaceutics.

The biodistribution of novel 200-nm palmitoyl muramic acid vesicles

I. Uchegbu, 1998 .

Exploring uptake mechanisms of oral nanomedicines using multimodal nonlinear optical microscopy

Julian Moger, Aikaterini Lalatsa, Andreas Schätzlein, 2012, Journal of biophotonics.

Drug delivery across the blood-brain barrier

I. Uchegbu, A. Schätzlein, A. Lalatsa, 2011 .

Chitosan amphiphile coating of peptide nanofibres reduces liver uptake and delivers the peptide to the brain on intravenous administration.

Michael A. Briggs, A. Schätzlein, I. Uchegbu, 2015, Journal of controlled release : official journal of the Controlled Release Society.

Hyaluronidase coated MET nanoparticles enhance drug absorption via the subcutaneous route.

A. Schätzlein, I. Uchegbu, A. Petkova, 2020, Molecular pharmaceutics.

Lomustine Nanoparticles Enable Both Bone Marrow Sparing and High Brain Drug Levels – A Strategy for Brain Cancer Treatments

A. Schätzlein, R. Satchi‐Fainaro, P. Stapleton, 2016, Pharmaceutical Research.

Polymer Hydrophobicity Has a Positive Effect on the Oral Absorption of Cyclosporine A from Poly(ethylenimine) Based Nanomedicines

A. Schätzlein, I. Uchegbu, H. Le, 2012 .

Preparation and in vitro/in vivo evaluation of luteinizing hormone releasing hormone (LHRH)-loaded polyhedral and spherical/tubular niosomes.

I. Uchegbu, A. Florence, J. Turton, 1999, Journal of pharmaceutical sciences.

Surface enhanced deep Raman detection of cancer tumour through 71 mm of heterogeneous tissue

P. Matousek, J. Baumberg, Benjamin Gardner, 2022, Nanotheranostics.

Brain Gene Silencing with Cationic Amino-Capped Poly(ethylene glycol) Polyplexes

A. Schätzlein, I. Uchegbu, David G Workman, 2022, Biomedicines.

Clustering superparamagnetic iron oxide nanoparticles produces organ-targeted high-contrast magnetic resonance images.

A. Schätzlein, I. Uchegbu, B. Siow, 2019, Nanomedicine.

The Role of Polymers in Solid Oral Dosage Forms

I. Uchegbu, 2006 .

Size-tuneable Nanometric MRI Contrast Agents for the Imaging of Molecular Weight Dependent Transport Processes

A. Schätzlein, I. Uchegbu, C. Dufès, 2015 .

High-resolution 3D isotropic MR imaging of mouse flank tumours obtained in vivo with solenoid RF micro-coil

A. Schätzlein, I. Uchegbu, C. Dufès, 2008, Physics in medicine and biology.

El-Hammadi, Mazen M. and MacLellan, Steven and Dufès, Christine and Holmes, William M. and Condon, Barrie and Uchegbu, Ijeoma F. and Schatzlein, Andreas G. (2014) Size-tuneable nanometric MRI contrast agents for the imaging of molecular weight dependent transport

A. Schatzlein, I. Uchegbu, C. Dufès, 2018 .

FULL TITLE Size-tuneable Nanometric MRI Contrast Agents for the Imaging of Molecular Weight Dependent Transport Processes AUTHORS NAMES AND AFFILIATION

A. Schatzlein, I. Uchegbu, C. Dufès, 2015 .

Cancer-specific transgene expression mediated by systemic injection of nanoparticles.

G. Vassaux, A. Schatzlein, I. Uchegbu, 2009, Cancer research.

Polymer Characterization Techniques

I. Uchegbu, 2006 .

In silico modelling of drug–polymer interactions for pharmaceutical formulations

Blair F. Johnston, P. Gellert, A. Schatzlein, 2010, Journal of The Royal Society Interface.

Nanomedicines for the Delivery of Biologics

R. Mrsny, F. Greco, A. Jones, 2019, Pharmaceutics.

Detecting polymeric nanoparticles with coherent anti-stokes Raman scattering microscopy in tissues exhibiting fixative-induced autofluorescence

Julian Moger, Natalie L. Garrett, Lisa Godfrey, 2015, Photonics West - Biomedical Optics.

Quaternary Ammonium Palmitoyl Glycol Chitosan (GCPQ) Loaded with Platinum-Based Anticancer Agents—A Novel Polymer Formulation for Anticancer Therapy

A. Schätzlein, M. Jakupec, B. Keppler, 2023, Pharmaceuticals.

A prodrug nanoparticle approach for the oral delivery of a hydrophilic peptide, leucine(5)-enkephalin, to the brain.

A. Schätzlein, M. Zloh, J. Malkinson, 2012, Molecular pharmaceutics.

Modified glycol chitosan nanocarriers carry hydrophobic materials into tumours

A. Schatzlein, I. Uchegbu, Abida Raza, 2010 .

pharmaceutical formulations polymer interactions for − modelling of drug In silico

Blair F. Johnston, P. Gellert, A. Schatzlein, 2010 .

High-capacity glycol chitosan-based nanoemulsion for efficient delivery of disulfiram.

A. Schätzlein, I. Uchegbu, Erazuliana Abd Kadir, 2023, International journal of pharmaceutics.

Preferential liver gene expression with polypropylenimine dendrimers.

Clive J Roberts, Martyn C Davies, Ijeoma F Uchegbu, 2005, Journal of controlled release : official journal of the Controlled Release Society.

Polymeric Chitosan‐based Vesicles for Drug Delivery

L. Tetley, I. Uchegbu, A. Schätzlein, 1998, The Journal of pharmacy and pharmacology.

Development of Bio-Functionalized, Raman Responsive, and Potentially Excretable Gold Nanoclusters

A. Schätzlein, I. Uchegbu, Ryan D Mellor, 2021, Nanomaterials.

A Self-Assembling Lipidic Peptide and Selective Partial V2 Receptor Agonist Inhibits Urine Production

A. Schätzlein, S. Haider, I. Uchegbu, 2020, Scientific Reports.

Dose - dependent delivery of genes to the cerebral cortex via the nasal route.

A. Schatzlein, I. Uchegbu, A. Petkova, 2023, International journal of pharmaceutics.

Surface enhanced deep Raman detection of cancer tumour through 71 mm of heterogeneous tissue

P. Matousek, J. Baumberg, Benjamin Gardner, 2022, Nanotheranostics.

The Effect of Monomers and of Micellar and Vesicular Forms of Non‐ionic Surfactants (Solulan C24 and Solulan 16) on Caco‐2 Cell Monolayers

I. Uchegbu, A. Florence, A. J. Shaw, 1997, The Journal of pharmacy and pharmacology.

The dendritic polymer DAB-Am16 as a novel tumoricidal compound

A. Schätzlein, I. Uchegbu, A. Mirenska, 2013 .

Osmotic Behaviour of Polyhedral Non‐ionic Surfactant Vesicles (Niosomes)

I. Uchegbu, A. Florence, P. Arunothayanun, 1999, The Journal of pharmacy and pharmacology.

Polymeric Micelles for the Enhanced Deposition of Hydrophobic Drugs into Ocular Tissues, without Plasma Exposure

A. Schätzlein, I. Uchegbu, U. Odunze, 2021, Pharmaceutics.

Direct in vivo evidence on the mechanism by which nanoparticles facilitate the absorption of a water insoluble, P-gp substrate.

A. Schätzlein, I. Uchegbu, K. Sasaki, 2016, International journal of pharmaceutics.

Label‐free imaging of polymeric nanomedicines using coherent anti‐stokes Raman scattering microscopy

Julian Moger, Natalie L. Garrett, Aikaterini Lalatsa, 2012 .

Nanomedicines in the treatment of brain tumors.

A. Schätzlein, F. Fisusi, I. Uchegbu, 2018, Nanomedicine.

Oral particle uptake and organ targeting drives the activity of amphotericin B nanoparticles.

A. Schätzlein, J. Guarro, I. Uchegbu, 2015, Molecular pharmaceutics.

Cancer-specific transgene expression mediated by systemic injection of nanoparticles.

G. Vassaux, A. Schatzlein, I. Uchegbu, 2009, Cancer research.

Quantification of beta-galactosidase activity after non-viral transfection in vivo.

A. Schätzlein, B. Zinselmeyer, I. Uchegbu, 2003, Journal of controlled release : official journal of the Controlled Release Society.

Nanotechnology in Drug Delivery

I. Uchegbu, A. Schätzlein, 2010 .

Limiting the level of tertiary amines on polyamines leads to biocompatible nucleic acid vectors.

A. Schätzlein, I. Uchegbu, J. Moger, 2017, International journal of pharmaceutics.

A nano-enabled cancer-specific ITCH RNAi chemotherapy booster for pancreatic cancer.

M. J. Santander-Ortega, A. Schätzlein, I. Uchegbu, 2015, Nanomedicine : nanotechnology, biology, and medicine.