I. Wheeldon

发表

Nanoscale tissue engineering: spatial control over cell-materials interactions

Ali Khademhosseini, Esmaiel Jabbari, Ian Wheeldon, 2011, Nanotechnology.

A sandwiched microarray platform for benchtop cell-based high throughput screening.

A. Khademhosseini, Yiqiao Hu, I. Wheeldon, 2011, Biomaterials.

An artificial vasculature for adaptive thermal control of windows

J. Aizenberg, D. Ingber, B. Hatton, 2013 .

A chimeric fusion protein engineered with disparate functionalities-enzymatic activity and self-assembly.

Scott Banta, I. Wheeldon, S. Banta, 2009, Journal of molecular biology.

Oxygen-reducing enzyme cathodes produced from SLAC, a small laccase from Streptomyces coelicolor.

P. Atanassov, I. Wheeldon, J. Gallaway, 2008, Biosensors & bioelectronics.

Design and Analysis of Enhanced Catalysis in Scaffolded Multienzyme Cascade Reactions

Ian Wheeldon, I. Wheeldon, Jyun-Liang Lin, 2014 .

The potential of multi-enzyme pathways to create novel anodes for enzymatic biofuel cells

I. Wheeldon, 2013 .

Validating genome-wide CRISPR-Cas9 function improves screening in the oleaginous yeast Yarrowia lipolytica.

James M. Wagner, S. Lonardi, H. Alper, 2019, Metabolic engineering.

Validating genome-wide CRISPR-Cas9 function in the non-conventional yeast Yarrowia lipolytica

James M. Wagner, S. Lonardi, H. Alper, 2018, bioRxiv.

Host and Pathway Engineering for Enhanced Lycopene Biosynthesis in Yarrowia lipolytica

I. Wheeldon, Cory M Schwartz, Keith Frogue, 2017, Front. Microbiol..

Western Blotting of Membrane-Bound Proteins in Yarrowia lipolytica.

I. Wheeldon, Adithya Ramesh, 2021, Methods in molecular biology.

Multiplexed CRISPR Activation of Cryptic Sugar Metabolism Enables Yarrowia Lipolytica Growth on Cellobiose.

I. Wheeldon, Cory M Schwartz, Ann-Kathrin Löbs, 2018, Biotechnology journal.

Highly Multiplexed CRISPRi Repression of Respiratory Functions Enhances Mitochondrial Localized Ethyl Acetate Biosynthesis in Kluyveromyces marxianus.

I. Wheeldon, Cory M Schwartz, Ann-Kathrin Löbs, 2018, ACS synthetic biology.

Bioactive proteinaceous hydrogels from designed bifunctional building blocks.

I. Wheeldon, S. Banta, S. Barton, 2007, Biomacromolecules.

Stress-tolerant non-conventional microbes enable next-generation chemical biosynthesis

I. Wheeldon, J. Chartron, Cory M Schwartz, 2020, Nature Chemical Biology.

Hydrolysis of lignocellulose by anaerobic fungi produces free sugars and organic acids for two‐stage fine chemical production with Kluyveromyces marxianus

Kevin V. Solomon, I. Wheeldon, Jacob A Englaender, 2021, Biotechnology progress.

Molecular binding scaffolds increase local substrate concentration enhancing the enzymatic hydrolysis of VX nerve agent

I. Wheeldon, Tamara C. Otto, Xiao Hong, 2020, Biotechnology and bioengineering.

A Closed Form Model for Molecular Ratchet-Type Chemically Induced Dimerization Modules.

Paul J. Steiner, Timothy A. Whitehead, Dmitri A. Nusinow, 2022, Biochemistry.

Enhancing Enzyme Activity and Immobilization in Nanostructured Inorganic-Enzyme Complexes.

I. Wheeldon, Yingning Gao, Lingling Zhu, 2017, Langmuir : the ACS journal of surfaces and colloids.

Design of Hybrid RNA Polymerase III Promoters for Efficient CRISPR-Cas9 Function.

I. Wheeldon, Cory M Schwartz, Joshua Misa, 2018, Bio-protocol.

Rapid biosensor development using plant hormone receptors as reprogrammable scaffolds

Paul J. Steiner, Zachary T Baumer, Timothy A. Whitehead, 2022, Nature biotechnology.

Simulation of a 25 kW Steam-Methanol Fuel Processor/PEM Fuel Cell System

J. C. Amphlett, R. F. Mann, M. Fowler, 2003 .

RNA polymerase II-driven CRISPR-Cas9 system for efficient non-growth-biased metabolic engineering of Kluyveromyces marxianus

N. D. Da Silva, I. Wheeldon, D. Bever, 2022, Metabolic engineering communications.

Rapid ester biosynthesis screening reveals a high activity alcohol-O-acyltransferase (AATase) from tomato fruit.

I. Wheeldon, Jie-ping Zhu, Jyun-Liang Lin, 2016, Biotechnology journal.

acCRISPR: an activity-correction method for improving the accuracy of CRISPR screens

S. Lonardi, I. Wheeldon, Cory M Schwartz, 2022, bioRxiv.

Mechanisms of Enhanced Catalysis in Enzyme–DNA Nanostructures Revealed through Molecular Simulations and Experimental Analysis

I. Wheeldon, Yingning Gao, C. Roberts, 2016, Chembiochem : a European journal of chemical biology.

Biomimetics with a self-assembled monolayer of catalytically active tethered isoalloxazine on Au.

I. Wheeldon, E. Calvo, M. Rothacher, 2005, Langmuir : the ACS journal of surfaces and colloids.

A reverse-selective ion exchange membrane for the selective transport of phosphates via an outer-sphere complexation–diffusion pathway

Z. Ren, I. Wheeldon, D. Jassby, 2022, Nature Nanotechnology.

Prospects of thermotolerant Kluyveromyces marxianus for high solids ethanol fermentation of lignocellulosic biomass

Charles M. Cai, C. Wyman, D. Kisailus, 2022, Biotechnology for Biofuels and Bioproducts.

Engineering enzyme microenvironments for enhanced biocatalysis.

I. Wheeldon, L. Lancaster, S. Banta, 2018, Chemical Society reviews.

Microbial Attachment Inhibition through Low-Voltage Electrochemical Reactions on Electrically Conducting Membranes.

Avner Ronen, I. Wheeldon, D. Jassby, 2015, Environmental science & technology.

Utilization of Biogas Generated from Ontario Wastewater Treatment Plants in Solid Oxide Fuel Cell Systems: A Process Modeling Study

Brant A. Peppley, Chris G. Caners, Ian Wheeldon, 2007 .

Bioelectrocatalytic hydrogels from electron-conducting metallopolypeptides coassembled with bifunctional enzymatic building blocks

Scott Calabrese Barton, Scott Banta, I. Wheeldon, 2008, Proceedings of the National Academy of Sciences.

Substrate channelling as an approach to cascade reactions.

Scott Calabrese Barton, Plamen Atanassov, Scott Banta, 2016, Nature chemistry.

Systemic immune responses to irradiated tumours via the transport of antigens to the tumour periphery by injected flagellate bacteria

Jinhui Wu, Yiqiao Hu, I. Wheeldon, 2022, Nature Biomedical Engineering.

Systemic immune responses to irradiated tumours via the transport of antigens to the tumour periphery by injected flagellate bacteria

Jinhui Wu, Yiqiao Hu, I. Wheeldon, 2022, Nature Biomedical Engineering.

Theory-Based Development of Performance Metrics for Comparing Multireactant Enzymes

I. Wheeldon, S. Banta, 2020 .

Microbial host selection affects intracellular localization and activity of alcohol-O-acetyltransferase

I. Wheeldon, Jie-ping Zhu, Jyun-Liang Lin, 2015, Microbial Cell Factories.

Dual N- and C-Terminal Helices Are Required for Endoplasmic Reticulum and Lipid Droplet Association of Alcohol Acetyltransferases in Saccharomyces cerevisiae

I. Wheeldon, Jyun-Liang Lin, 2014, PloS one.

Standardized Markerless Gene Integration for Pathway Engineering in Yarrowia lipolytica.

I. Wheeldon, M. Blenner, Cory M Schwartz, 2017, ACS synthetic biology.

Genome and metabolic engineering in non-conventional yeasts: Current advances and applications

I. Wheeldon, Cory M Schwartz, Ann-Kathrin Löbs, 2017, Synthetic and systems biotechnology.

Genome-wide functional screens enable the prediction of high activity CRISPR-Cas9 and -Cas12a guides in Yarrowia lipolytica

S. Lonardi, I. Wheeldon, Cory M Schwartz, 2021, bioRxiv.

Guide RNA engineering enables dual purpose CRISPR-Cpf1 for simultaneous gene editing and gene regulation in Yarrowia lipolytica.

I. Wheeldon, J. Adams, Adithya Ramesh, 2020, ACS synthetic biology.

CRISPR-Cas9-Mediated Genome Editing and Transcriptional Control in Yarrowia lipolytica.

I. Wheeldon, Cory M Schwartz, 2018, Methods in molecular biology.

Microscale Biomaterials for Tissue Engineering

H. Kaji, A. Khademhosseini, Hojae Bae, 2011 .

Spot identification and quality control in cell-based microarrays.

Ali Khademhosseini, Keekyoung Kim, Ronglih Liao, 2012, ACS combinatorial science.

CRISPRi repression of nonhomologous end‐joining for enhanced genome engineering via homologous recombination in Yarrowia lipolytica

I. Wheeldon, Cory M Schwartz, Keith Frogue, 2017, Biotechnology and bioengineering.

Synthetic RNA Polymerase III Promoters Facilitate High-Efficiency CRISPR-Cas9-Mediated Genome Editing in Yarrowia lipolytica.

Ian Wheeldon, Mark Blenner, I. Wheeldon, 2016, ACS synthetic biology.

Controlled intracellular trafficking alleviates an expression bottleneck in S. cerevisiae ester biosynthesis

I. Wheeldon, Jie-ping Zhu, Cory M Schwartz, 2018, Metabolic engineering communications.

Synthetic Protein Scaffolds for Biosynthetic Pathway Colocalization on Lipid Droplet Membranes.

I. Wheeldon, Jie-ping Zhu, Jyun-Liang Lin, 2017, ACS synthetic biology.

CRISPR-mediated multigene integration enables Shikimate pathway refactoring for enhanced 2-phenylethanol biosynthesis in Kluyveromyces marxianus

N. D. Da Silva, I. Wheeldon, Xuye Lang, 2021, Biotechnology for Biofuels.

Tuning Enzyme Kinetics through Designed Intermolecular Interactions Far from the Active Site

Jie Zhu, I. Wheeldon, Jyun-Liang Lin, 2015 .

High throughput, colorimetric screening of microbial ester biosynthesis reveals high ethyl acetate production from Kluyveromyces marxianus on C5, C6, and C12 carbon sources.

I. Wheeldon, Jyun-Liang Lin, Ann-Kathrin Löbs, 2016, Biotechnology journal.

CRISPR–Cas9-enabled genetic disruptions for understanding ethanol and ethyl acetate biosynthesis in Kluyveromyces marxianus

I. Wheeldon, Cory M Schwartz, Ann-Kathrin Löbs, 2017, Biotechnology for Biofuels.

Microenvironmental effects can masquerade as substrate channelling in cascade biocatalysis.

I. Wheeldon, S. Banta, Xiao Hong, 2021, Current opinion in biotechnology.

A Strong Hybrid Fatty Acid Inducible Transcriptional Sensor Built From Yarrowia lipolytica Upstream Activating and Regulatory Sequences

I. Wheeldon, M. Blenner, Murtaza Shabbir Hussain, 2017, Biotechnology journal.

Population genomics-guided engineering of phenazine biosynthesis in Pseudomonas chlororaphis

I. Wheeldon, Varun Trivedi, Sarah Thorwall, 2023, bioRxiv.

Protein engineering in the development of functional hydrogels.

Scott Banta, Ian R Wheeldon, Mark Blenner, 2010, Annual review of biomedical engineering.

Genome-wide functional screens enable the prediction of high activity CRISPR-Cas9 and -Cas12a guides in Yarrowia lipolytica

S. Lonardi, I. Wheeldon, Cory M Schwartz, 2021, Nature Communications.

DNA Nanostructure Sequence-Dependent Binding of Organophosphates.

I. Wheeldon, Yingning Gao, A. Toop, 2017, Langmuir : the ACS journal of surfaces and colloids.

Integration of heterogeneous and biochemical catalysis for production of fuels and chemicals from biomass.

Phillip Christopher, Ian Wheeldon, H. Blanch, 2017, Current opinion in biotechnology.

Kinetic Enhancements in DNA–Enzyme Nanostructures Mimic the Sabatier Principle

I. Wheeldon, Jyun-Liang Lin, 2013 .

Catalysis of Thermostable Alcohol Dehydrogenase Improved by Engineering the Microenvironment through Fusion with Supercharged Proteins

I. Wheeldon, S. Banta, Walaa Abdallah, 2019, Chembiochem : a European journal of chemical biology.

Bioinspired design of a hybrid bifunctional enzymatic/organic electrocatalyst for site selective alcohol oxidation.

David P. Hickey, S. Minteer, I. Wheeldon, 2018, Chemical communications.

Drug-eluting microarrays for cell-based screening of chemical-induced apoptosis.

A. Khademhosseini, N. Kachouie, S. Sant, 2011, Analytical chemistry.

Catalytic biomaterials: engineering organophosphate hydrolase to form self-assembling enzymatic hydrogels.

I. Wheeldon, S. Banta, H. Lu, 2010, Protein engineering, design & selection : PEDS.

Multiscale simulation-guided design of enzyme bioconjugates with enhanced catalysis.

I. Wheeldon, T. Cholko, Xiao Hong, 2022, Chem catalysis.

Broadening the cofactor specificity of a thermostable alcohol dehydrogenase using rational protein design introduces novel kinetic transient behavior

Scott Banta, I. Wheeldon, S. Banta, 2010, Biotechnology and bioengineering.

Genome‐wide CRISPR‐Cas9 screen reveals a persistent null‐hyphal phenotype that maintains high carotenoid production in Yarrowia lipolytica

I. Wheeldon, Cory M Schwartz, Adithya Ramesh, 2022, Biotechnology and bioengineering.

Protein Engineering Strategies for Modular, Responsive and Spatially Organized Biomaterials

Ian Wheeldon, I. Wheeldon, 2014 .

Enzyme colocalization in protein-based hydrogels.

I. Wheeldon, L. Lancaster, B. Bulutoglu, 2019, Methods in enzymology.

Microengineering Hydrogels for Stem Cell Bioengineering and Tissue Regeneration

Ali Khademhosseini, Ian Wheeldon, Amirhossein F Ahari, 2010, JALA.

Guide RNA Design for Genome-Wide CRISPR Screens in Yarrowia lipolytica.

I. Wheeldon, Adithya Ramesh, 2021, Methods in molecular biology.

The Importance and Future of Biochemical Engineering.

Kristala L J Prather, Rashmi Kshirsagar, Beth Junker, 2020, Biotechnology and bioengineering.

Validating genome-wide CRISPR-Cas9 function in the non-conventional yeast Yarrowia lipolytica

James M. Wagner, S. Lonardi, H. Alper, 2018, bioRxiv.

Integration of heterogeneous and biochemical catalysis for production of fuels and chemicals from biomass.

H. Blanch, I. Wheeldon, P. Christopher, 2017, Current Opinion in Biotechnology.

An orthogonalized PYR1-based CID module with reprogrammable ligand-binding specificity

Dmitri A. Nusinow, B. Volkman, F. Peterson, 2023, Nature chemical biology.

Stream Monitoring and Stewardship Programme Involving a Partnership Between Community Organizations, High Schools and a University

G. Bae, R. F. Io, F. Lee, 1997 .

Catalysis of Thermostable Alcohol Dehydrogenase Improved by Engineering the Microenvironment through Fusion with Supercharged Proteins

I. Wheeldon, S. Banta, Walaa Abdallah, 2019, Chembiochem : a European journal of chemical biology.

Repurposing plant hormone receptors as chemically-inducible genetic switches for dynamic regulation in yeast.

I. Wheeldon, Sang-Youl Park, Xuye Lang, 2024, Metabolic engineering.

GMMA can stabilize proteins across different functional constraints

Zachary T Baumer, K. E. Johansson, K. Lindorff-Larsen, 2024, bioRxiv.

Optimized genome-wide CRISPR screening enables rapid engineering of growth-based phenotypes in Yarrowia lipolytica

Robert E. Jinkerson, I. Wheeldon, Adithya Ramesh, 2024, bioRxiv.