J. A. MacKay

发表

Elastin-like peptide amphiphiles form nanofibers with tunable length.

S. Aluri, M. Pastuszka, A. S. Moses, 2012, Biomacromolecules.

Mechanism of pH-triggered collapse of phosphatidylethanolamine liposomes stabilized by an ortho ester polyethyleneglycol lipid.

F. Szoka, J. A. MacKay, Xin Guo, 2003, Biophysical journal.

Imaging and drug delivery using theranostic nanoparticles.

A. S. Moses, J. A. MacKay, S. M. Janib, 2010, Advanced drug delivery reviews.

Fabrication of elastin-like polypeptide nanoparticles for drug delivery by electrospraying.

Jonathan R. McDaniel, R. Clark, A. Chilkoti, 2009, Biomacromolecules.

Switchable elastin-like polypeptides that respond to chemical inducers of dimerization.

Isaac Weitzhandler, J. A. MacKay, J. Dhandhukia, 2013, Biomacromolecules.

Distribution in brain of liposomes after convection enhanced delivery; modulation by particle charge, particle diameter, and presence of steric coating

F. Szoka, D. Deen, J. A. MacKay, 2005, Brain Research.

HIV TAT Protein Transduction Domain Mediated Cell Binding and Intracellular Delivery of Nanoparticles.

F. Szoka, J. A. MacKay, 2003, Journal of dispersion science and technology.

Berunda polypeptides carrying rapalogues inhibit tumor mTORC1 better than oral everolimus.

J. A. MacKay, Santosh Peddi, 2020, Biomacromolecules.

Kinetic quantification of protein polymer nanoparticles using non-invasive imaging.

P. Conti, R. Park, Zibo Li, 2013, Integrative biology : quantitative biosciences from nano to macro.

Designing dendrimers for biological applications

Francis C Szoka, F. Szoka, J. A. MacKay, 2005, Nature Biotechnology.

Genetically engineered nanocarriers for drug delivery

J. A. MacKay, Joshua A. Gustafson, Joshua A Gustafson, 2014, International journal of nanomedicine.

Design and cellular internalization of genetically engineered polypeptide nanoparticles displaying adenovirus knob domain.

J. A. MacKay, S. Hamm-Alvarez, S. M. Janib, 2011, Journal of controlled release : official journal of the Controlled Release Society.

Biodegradation of elastin‐like polypeptide nanoparticles

J. A. MacKay, S. M. Janib, Guoyong Sun, 2012, Protein science : a publication of the Protein Society.

A tunable and reversible platform for the intracellular formation of genetically engineered protein microdomains.

Isaac Weitzhandler, M. Pastuszka, J. A. MacKay, 2012, Biomacromolecules.

A rapamycin-binding protein polymer nanoparticle shows potent therapeutic activity in suppressing autoimmune dacryoadenitis in a mouse model of Sjögren's syndrome.

J. A. MacKay, S. Hamm-Alvarez, J. Dhandhukia, 2013, Journal of controlled release : official journal of the Controlled Release Society.

A quantitative recipe for engineering protein polymer nanoparticles.

Yi-an, H. Cui, S. Aluri, 2014, Polymer chemistry.

Nanotoxicology of an elastin-like polypeptide rapamycin formulation for breast cancer.

J. A. MacKay, Santosh Peddi, S. Roberts, 2020, Biomacromolecules.

Berunda Polypeptides: Biheaded Rapamycin Carriers for Subcutaneous Treatment of Autoimmune Dry Eye Disease.

J. A. MacKay, S. Hamm-Alvarez, M. Edman, 2019, Molecular pharmaceutics.

Quantitative model of the phase behavior of recombinant pH-responsive elastin-like polypeptides.

Daniel J. Callahan, A. Chilkoti, J. A. MacKay, 2010, Biomacromolecules.

Thiocholesterol-based lipids for ordered assembly of bioresponsive gene carriers.

F. Szoka, J. A. MacKay, Weijun Li, 2005, Molecular therapy : the journal of the American Society of Gene Therapy.

Tear-mediated delivery of nanoparticles through transcytosis of the lacrimal gland.

H. Cui, Yi-an Lin, J. A. MacKay, 2015, Journal of controlled release : official journal of the Controlled Release Society.

Live long and active: Polypeptide-mediated assembly of antibody variable fragments.

J. A. MacKay, Changrim Lee, Minchang Choi, 2020, Advanced drug delivery reviews.

Theranostic agents that co-deliver therapeutic and imaging agents?

Zibo Li, J. A. MacKay, 2010, Advanced drug delivery reviews.

Protein polymer nanoparticles engineered as chaperones protect against apoptosis in human retinal pigment epithelial cells.

H. Cui, Yi-an Lin, J. A. MacKay, 2014, Journal of controlled release : official journal of the Controlled Release Society.

Designing dendrimers for biological

F. Szoka, J. A. MacKay, J. Fréchet, 2005 .

Rapamycin Eye Drops Suppress Lacrimal Gland Inflammation In a Murine Model of Sjögren's Syndrome

C. Ding, J. A. MacKay, S. Hamm-Alvarez, 2017, Investigative ophthalmology & visual science.

Cornea Rapamycin Eye Drops Suppress Lacrimal Gland Inflammation In a Murine Model of Sjögren ’ s Syndrome

J. A. MacKay, S. Hamm-Alvarez, M. Edman, 2017 .

The humanin peptide mediates ELP nanoassembly and protects human retinal pigment epithelial cells from oxidative stress.

J. A. MacKay, D. Hinton, R. Kannan, 2020, Nanomedicine : nanotechnology, biology, and medicine.

Molecular Targeting of Immunosuppressants Using a Bi-functional Elastin-Like Polypeptide.

J. A. MacKay, S. Hamm-Alvarez, M. Edman, 2019, Bioconjugate chemistry.

Acid-triggered transformation of diortho ester phosphocholine liposome.

F. Szoka, J. A. MacKay, Weijun Li, 2006, Journal of the American Chemical Society.

Intra-lacrimal Sustained Delivery of Rapamycin Shows Therapeutic Effects Without Systemic Toxicity in a Mouse Model of Autoimmune Dacryoadenitis Characteristic of Sjögren’s Syndrome

J. A. MacKay, J. Junge, S. Hamm-Alvarez, 2021 .

Berunda Polypeptides: Multi-Headed Fusion Proteins Promote Subcutaneous Administration of Rapamycin to Breast Cancer In Vivo

David R. Tyrpak, J. A. MacKay, J. Dhandhukia, 2017, Theranostics.

HIV TAT peptide modifies the distribution of DNA nanolipoparticles following convection-enhanced delivery.

F. Szoka, D. Deen, T. Tihan, 2008, Molecular therapy : the journal of the American Society of Gene Therapy.

NANOSCALE SELF-ASSEMBLY FOR DELIVERY OF THERAPEUTICS AND IMAGING AGENTS.

Jonathan R. McDaniel, A. Chilkoti, J. A. MacKay, 2011, Technology & Innovation.

Multimeric Disintegrin Protein Polymer Fusions That Target Tumor Vasculature

P. Conti, Zibo Li, H. Cui, 2014, Biomacromolecules.

A Human Granulocyte-Macrophage Colony-Stimulating Factor Fused to Elastin-like Polypeptides Assembles Biologically-Active Nanoparticles.

J. A. MacKay, Mincheol Park, J. Dhandhukia, 2020, Bioconjugate chemistry.

Intracellular Delivery of Rapamycin From FKBP Elastin-Like Polypeptides Is Consistent With Macropinocytosis

J. A. MacKay, Santosh Peddi, Xiaoli Pan, 2018, Front. Pharmacol..

Adaptable antibody Nanoworms designed for non-Hodgkin lymphoma.

Caleb F. Anderson, H. Cui, Hao Su, 2020, Biomaterials.

NOD and NOR mice exhibit comparable development of lacrimal gland secretory dysfunction but NOD mice have more severe autoimmune dacryoadenitis

J. A. MacKay, S. Hamm-Alvarez, M. Edman, 2018, Experimental eye research.

Bet v 1-displaying elastin-like polypeptide nanoparticles induce a strong humoral and weak CD4+ T-cell response against Bet v 1 in a murine immunogenicity model

R. Van Ree, R. Olsthoorn, W. Jiskoot, 2022, Frontiers in Immunology.

Single-Cell Quantification of the Transition Temperature of Intracellular Elastin-like Polypeptides.

David R. Tyrpak, J. A. MacKay, Yaocun Li, 2021, ACS biomaterials science & engineering.

Anti-CD99 scFv-ELP nanoworms for the treatment of acute myeloid leukemia.

J. A. MacKay, Mincheol Park, H. Alachkar, 2020, Nanomedicine : nanotechnology, biology, and medicine.

Triggered Sorting and Co‐Assembly of Genetically Engineered Protein Microdomains in the Cytoplasm

H. Cui, Yi-an Lin, M. Pastuszka, 2014, Advanced materials.

Inhibition of Cathepsin S Reduces Lacrimal Gland Inflammation and Increases Tear Flow in a Mouse Model of Sjögren’s Syndrome

J. A. MacKay, S. Hamm-Alvarez, M. Edman, 2019, Scientific Reports.

Anti-FLT3 nanoparticles for acute myeloid leukemia: Preclinical pharmacology and pharmacokinetics.

J. A. MacKay, Mincheol Park, H. Alachkar, 2020, Journal of controlled release : official journal of the Controlled Release Society.

Improved non-chromatographic purification of a recombinant protein by cationic elastin-like polypeptides.

A. Chilkoti, D. Lim, J. A. MacKay, 2007, Biomacromolecules.

A Hybrid Protein–Polymer Nanoworm Potentiates Apoptosis Better than a Monoclonal Antibody

P. Conti, Zibo Li, H. Cui, 2014, ACS nano.

New biologically active cyclophosphazene derivatives

R. Newman, J. A. MacKay, M. Hacker, 1982 .

A thermo-responsive protein treatment for dry eyes.

G. Laurie, S. Aluri, J. A. MacKay, 2015, Journal of controlled release : official journal of the Controlled Release Society.

In situ growth of a stoichiometric PEG-like conjugate at a protein's N-terminus with significantly improved pharmacokinetics

E. Toone, A. Chilkoti, J. A. MacKay, 2009, Proceedings of the National Academy of Sciences.

Recursive directional ligation by plasmid reconstruction allows rapid and seamless cloning of oligomeric genes.

Felipe García Quiroz, Ashutosh Chilkoti, Jonathan R. McDaniel, 2010, Biomacromolecules.

Self-assembling chimeric polypeptide-doxorubicin conjugate nanoparticles that abolish tumors after a single injection

Ashutosh Chilkoti, Jonathan R. McDaniel, J. Andrew MacKay, 2009, Nature materials.

A new temperature-dependent strategy to modulate the epidermal growth factor receptor.

David R. Tyrpak, J. A. MacKay, Mincheol Park, 2018, Biomaterials.

Elastin‐like polypeptide switches: A design strategy to detect multimeric proteins

M. Pastuszka, J. A. MacKay, J. Dhandhukia, 2017, Protein science : a publication of the Protein Society.

Structural Analyses Reveal Phosphatidyl Inositols as Ligands for the NR5 Orphan Receptors SF-1 and LRH-1

T. Willson, R. Fletterick, R. Guy, 2005, Cell.

Tunable Assembly of Protein‐Microdomains in Living Vertebrate Embryos

David R. Tyrpak, C. Lien, J. A. MacKay, 2018, Advanced biosystems.

Biomolecular engineering of intracellular switches in eukaryotes.

M. Pastuszka, J. A. MacKay, 2010, Journal of drug delivery science and technology.

Bifunctional Elastin-like Polypeptide Nanoparticles Bind Rapamycin and Integrins and Suppress Tumor Growth in Vivo.

H. Cui, Yi-an Lin, S. Aluri, 2017, Bioconjugate chemistry.

Environmentally responsive peptides as anticancer drug carriers.

S. Aluri, J. A. MacKay, S. M. Janib, 2009, Advanced drug delivery reviews.

A Multivalent ICAM-1 Binding Nanoparticle which Inhibits ICAM-1 and LFA-1 Interaction Represents a New Tool for the Investigation of Autoimmune-Mediated Dry Eye

J. A. MacKay, S. Hamm-Alvarez, M. Edman, 2020, International journal of molecular sciences.

Supra-lacrimal protein-based carriers for cyclosporine A reduce Th17-mediated autoimmunity in murine model of Sjögren's syndrome.

J. A. MacKay, S. Hamm-Alvarez, M. Edman, 2022, Biomaterials.

Elastin-like polypeptides: Therapeutic applications for an emerging class of nanomedicines.

J. A. MacKay, S. Hamm-Alvarez, J. Dhandhukia, 2016, Journal of controlled release : official journal of the Controlled Release Society.

Stimulus responsive elastin biopolymers: Applications in medicine and biotechnology.

Ashutosh Chilkoti, A. Chilkoti, J. A. MacKay, 2006, Current opinion in chemical biology.

Injectable intratumoral depot of thermally responsive polypeptide-radionuclide conjugates delays tumor progression in a mouse model.

Jonathan R. McDaniel, Daniel J. Callahan, A. Chilkoti, 2010, Journal of controlled release : official journal of the Controlled Release Society.

An amphipathic alpha-helical peptide from apolipoprotein A1 stabilizes protein polymer vesicles.

H. Cui, L. Lock, M. Pastuszka, 2014, Journal of controlled release : official journal of the Controlled Release Society.

Thermally-Responsive Loading and Release of Elastin-Like Polypeptides from Contact Lenses

G. Laurie, M. Pastuszka, J. A. MacKay, 2019, Pharmaceutics.

Intra‐vitreal &agr;B crystallin fused to elastin‐like polypeptide provides neuroprotection in a mouse model of age‐related macular degeneration

J. A. MacKay, D. Hinton, Wan Wang, 2018, Journal of controlled release : official journal of the Controlled Release Society.

Image-driven pharmacokinetics: nanomedicine concentration across space and time.

J. A. MacKay, Dab A Brill, Dab Brill, 2015, Nanomedicine.

Low-pH-sensitive PEG-stabilized plasmid-lipid nanoparticles: preparation and characterization.

Francis C Szoka, F. Szoka, J. Choi, 2003, Bioconjugate chemistry.

A pharmacokinetics primer for preclinical nanomedicine research

Hao Guo, John Andrew MacKay, J. A. MacKay, 2020 .

Biomimetic SARS-CoV-2 Spike Protein Nanoparticles

J. A. MacKay, Hugo Avila, Alvin Phan, 2023, Biomacromolecules.

Flipping the Switch on Clathrin‐Mediated Endocytosis using Thermally Responsive Protein Microdomains

M. Pastuszka, J. A. MacKay, C. Okamoto, 2014, Advanced functional materials.

Elastin-based protein polymer nanoparticles carrying drug at both corona and core suppress tumor growth in vivo.

H. Cui, Yi-an Lin, S. Aluri, 2013, Journal of controlled release : official journal of the Controlled Release Society.

Inhibition of Cathepsin S Reduces Lacrimal Gland Inflammation and Increases Tear Flow in a Mouse Model of Sjögren’s Syndrome

J. A. MacKay, S. Hamm-Alvarez, M. Edman, 2019, Scientific Reports.

Intracellular Dynamin Elastin-like Polypeptides Assemble into Rodlike, Spherical, and Reticular Dynasomes.

David R. Tyrpak, J. A. MacKay, C. Okamoto, 2021, Biomacromolecules.

Engineering structure and function using thermoresponsive biopolymers.

M. Pastuszka, J. A. MacKay, 2016, Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology.

Biosynthesized Multivalent Lacritin Peptides Stimulate Exosome Production in Human Corneal Epithelium

G. Laurie, J. A. MacKay, S. Hamm-Alvarez, 2020, International journal of molecular sciences.

Caveolin elastin-like polypeptide fusions mediate temperature-dependent assembly of caveolar microdomains.

David R. Tyrpak, Yue Wang, J. A. MacKay, 2019, ACS biomaterials science & engineering.