S. Costa

发表

Serum antibody response to Human papillomavirus (HPV) infections detected by a novel ELISA technique based on denatured recombinant HPV16 L1, L2, E4, E6 and E7 proteins

L. Mariani, K. Syrjänen, P. Di Bonito, 2006, Infectious Agents and Cancer.

Matrix metalloproteinase-2 (MMP-2) and its tissue inhibitor (TIMP-2) are prognostic factors in cervical cancer, related to invasive disease but not to high-risk human papillomavirus (HPV) or virus persistence after treatment of CIN.

D. Santini, S. Syrjänen, K. Syrjänen, 2006, Anticancer research.

Covariates of high-risk human papillomavirus (HPV) infections are distinct for incident CIN1, CIN2 and CIN3 as disclosed by competing-risks regression models.

S. Tatti, A. Longatto-Filho, S. Syrjänen, 2012, European journal of gynaecological oncology.

Up-regulation of proliferating cell nuclear antigen (PCNA) is closely associated with high-risk human papillomavirus (HPV) and progression of cervical intraepithelial neoplasia (CIN), but does not predict disease outcome in cervical cancer.

D. Santini, S. Syrjänen, K. Syrjänen, 2007, European journal of obstetrics, gynecology, and reproductive biology.

Competing-Risks Regression Models in Analysis of Biomarkers as Predictors of High-risk Human Papillomavirus (HPV) Infection Outcomes and Incident CIN in the LAMS Cohort

S. Tatti, S. Syrjänen, K. Syrjänen, 2013, International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists.

Up-regulation of lipocalin 2 is associated with high-risk human papillomavirus and grade of cervical lesion at baseline but does not predict outcomes of infections or incident cervical intraepithelial neoplasia.

S. Tatti, A. Longatto-Filho, S. Syrjänen, 2010, American journal of clinical pathology.

Up-regulation of 14-3-3sigma (Stratifin) is associated with high-grade CIN and high-risk human papillomavirus (HPV) at baseline but does not predict outcomes of HR-HPV infections or incident CIN in the LAMS study.

S. Tatti, S. Syrjänen, K. Syrjänen, 2010, American journal of clinical pathology.

Up-regulation of plasminogen activator inhibitor-2 is associated with high-risk HPV and grade of cervical lesion at baseline but does not predict outcomes of high-risk HPV infections or incident CIN.

S. Tatti, A. Longatto-Filho, S. Syrjänen, 2009, American journal of clinical pathology.

Drug addiction is not an independent risk factor for oncogenic human papillomavirus infections or high-grade cervical intraepithelial neoplasia: case-control study nested within the Latin American Screening study cohort

S. Tatti, A. Longatto-Filho, S. Syrjänen, 2008, International journal of STD & AIDS.

Clinical and epidemiological correlates of antibody response to human papillomaviruses (HPVs) as measured by a novel ELISA based on denatured recombinant HPV16 late (L) and early (E) antigens

L. Mariani, K. Syrjänen, P. Di Bonito, 2008, Infectious Agents and Cancer.

Upregulation of telomerase (hTERT) is related to the grade of cervical intraepithelial neoplasia, but is not an independent predictor of high‐risk human papillomavirus, virus persistence, or disease outcome in cervical cancer

L. Mariani, M. Ruutu, D. Santini, 2006, Diagnostic cytopathology.

Evaluation of visual inspection with acetic acid (VIA), Lugol's iodine (VILI), cervical cytology and HPV testing as cervical screening tools in Latin America: This report refers to partial results from the LAMS (Latin AMerican Screening) study

S. Tatti, A. Longatto-Filho, S. Syrjänen, 2005 .

Neoadjuvant chemotherapy in cervical carcinoma: regulators of cell cycle, apoptosis, and proliferation as determinants of response to therapy and disease outcome.

D. Santini, S. Syrjänen, P. Lipponen, 2001, American journal of clinical pathology.

Is vestibular papillomatosis associated with human papillomavirus?

P. Secchiero, S. Costa, A. Rotola, 1991, Journal of medical virology.

Search for human papillomavirus, herpes simplex virus and c‐myc oncogene in human genital tumors

P. Monini, W. Grigioni, S. Costa, 1989, International journal of cancer.

Clinical Epidemiology of Microinvasive Cervical Carcinoma in an Italian Population Targeted by a Screening Programme

S. Costa, P. Giorgi Rossi, S. Ferretti, 2022, Cancers.

Beta-interferon treatment of cervical intraepithelial neoplasia: a multicenter clinical trial.

S. Costa, A. Rotola, D. Di Luca, 1995, Intervirology.

Incidence and survival trends of cervical adenocarcinoma in Italy: Cytology screening has become more effective in downstaging the disease but not in detecting its precursors

S. Costa, S. Ferretti, F. Falcini, 2017, International journal of cancer.

Rationale and development of an on-line quality assurance programme for colposcopy in a population-based cervical screening setting in Italy

S. Costa, M. Sideri, P. Cristiani, 2013, BMC Health Services Research.

Interpretation of colposcopy in population-based cervical screening services in north-eastern Italy: an online interregional agreement study.

S. Costa, S. Ferretti, P. Cristiani, 2016, European journal of obstetrics, gynecology, and reproductive biology.

An Online Quality Assurance Program for Colposcopy in a Population-Based Cervical Screening Setting in Italy: Results on Colposcopic Impression

S. Costa, M. Sideri, P. Cristiani, 2014, Journal of lower genital tract disease.

Expression of CD44 splice variants in normal, dysplastic, and neoplastic cervical epithelium.

M. Zöller, S. Costa, S. Woerner, 1995, Clinical cancer research : an official journal of the American Association for Cancer Research.

Detection of Human Papillomavirus Infections in the Male Sexual Partners of Women Attending an STD Clinic in Bologna

S. Syrjänen, K. Syrjänen, S. Costa, 1992, International journal of STD & AIDS.

Smoking worsens the prognosis of mild abnormalities in cervical cytology

S. Tatti, A. Longatto-Filho, S. Syrjänen, 2009, Acta obstetricia et gynecologica Scandinavica.

Performance of HPV DNA testing in the follow-up after treatment of high-grade cervical lesions, adenocarcinoma in situ (AIS) and microinvasive carcinoma

L. Mariani, P. Cristoforoni, S. Costa, 2015, Ecancermedicalscience.

Performance characteristics of Pap test, VIA, VILI, HR-HPV testing, cervicography, and colposcopy in diagnosis of significant cervical pathology

Margherita Branca, Cecília Roteli-Martins, Kari Syrjänen, 2012, Virchows Archiv.

Expression of cell-cycle–associated proteins pRB2/p130 and p27kip1 in vulvar squamous cell carcinomas

C. Cinti, A. Giordano, D. Santini, 2001 .

Impact of sexual habits on the clinical evaluation of male HPV infection

P. Monini, S. Costa, A. Rotola, 1994, European Journal of Epidemiology.

Increased Risk of Oncogenic Human Papillomavirus Infections and Incident High-Grade Cervical Intraepithelial Neoplasia Among Smokers: Experience From the Latin American Screening Study

S. Tatti, A. Longatto-Filho, S. Syrjänen, 2009, Sexually transmitted diseases.

Clinicopathologic analysis of 370 cases of vulvar intraepithelial neoplasia. Italian Study Group on Vulvar Disease.

L. Mariani, P. Carli, D. Gerbaldo, 1996, The Journal of reproductive medicine.

Mapping of linear epitopes of human papillomavirus type 16: The L1 and L2 open reading frames

J. Dillner, S. Costa, C. Eklund, 1990, International journal of cancer.

Predicting High-Risk Human Papillomavirus Infection, Progression of Cervical Intraepithelial Neoplasia, and Prognosis of Cervical Cancer With a Panel of 13 Biomarkers Tested in Multivariate Modeling

D. Santini, S. Syrjänen, K. Syrjänen, 2008, International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists.

Over-Expression of Topoisomerase II&agr; is Related to the Grade of Cervical Intraepithelial Neoplasia (CIN) and High-Risk Human Papillomavirus (HPV), but does not Predict Prognosis in Cervical Cancer or HPV Clearance after Cone Treatment

L. Mariani, D. Santini, S. Syrjänen, 2006, International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists.

Viral DNA load, physical status and E2/E6 ratio as markers to grade HPV16 positive women for high-grade cervical lesions.

S. Costa, A. Morselli-Labate, M. Zerbini, 2007, Gynecologic oncology.

HPV DNA patterns and disease implications in the follow‐up of patients treated for HPV16 high‐grade carcinoma in situ

D. Santini, S. Costa, M. Zerbini, 2006, Journal of medical virology.

Accuracy of Colposcopically Directed Biopsy: Results from an Online Quality Assurance Programme for Colposcopy in a Population-Based Cervical Screening Setting in Italy

S. Costa, M. Sideri, P. Cristiani, 2015, BioMed research international.

Correlation of high‐risk human papillomavirus genotypes persistence and risk of residual or recurrent cervical disease after surgical treatment

E. Leo, S. Costa, M. Zerbini, 2008, Journal of medical virology.

Human papillomavirus (HPV) test and PAP smear as predictors of outcome in conservatively treated adenocarcinoma in situ (AIS) of the uterine cervix.

G. Martinelli, D. Santini, S. Costa, 2007, Gynecologic oncology.

Factors predicting human papillomavirus clearance in cervical intraepithelial neoplasia lesions treated by conization.

D. Santini, S. Syrjänen, K. Syrjänen, 2003, Gynecologic oncology.

Down-regulation of E-cadherin is closely associated with progression of cervical intraepithelial neoplasia (CIN), but not with high-risk human papillomavirus (HPV) or disease outcome in cervical cancer.

L. Mariani, D. Santini, S. Syrjänen, 2006, European journal of gynaecological oncology.

Factors associated with cone margin involvement in CIN patients undergoing conization‐equivalent electrosurgical procedure

D. Santini, A. Bovicelli, S. Costa, 2000, Acta obstetricia et gynecologica Scandinavica.

p16INK4A Expression Is Related to Grade of CIN and High-risk Human Papillomavirus but Does not Predict Virus Clearance After Conization or Disease Outcome

D. Santini, K. Syrjänen, M. Branca, 2004, International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists.

Persistent High-Risk Human Papillomavirus Infections and Other End-Point Markers of Progressive Cervical Disease Among Women Prospectively Followed up in the New Independent States of the Former Soviet Union and the Latin American Screening Study Cohorts

S. Tatti, A. Longatto-Filho, S. Syrjänen, 2009, International Journal of Gynecologic Cancer.

Outcome of Conservatively Treated Microinvasive Squamous Cell Carcinoma of the Uterine Cervix During a 10-Year Follow-up

G. Martinelli, D. Santini, K. Syrjänen, 2009, International Journal of Gynecologic Cancer.

VIN usual type—from the past to the future

L. Mariani, P. Cristoforoni, S. Costa, 2015, ecancermedicalscience.

Molecular Markers Implicating Early Malignant Events in Cervical Carcinogenesis

K. Kurvinen, S. Syrjänen, K. Syrjänen, 2010, Cancer Epidemiology, Biomarkers & Prevention.

ecular Markers Implicating Early Malignant Events in B & P vical Carcinogenesis

K. Kurvinen, S. Syrjänen, K. Syrjänen, 2010 .

HPV-Testing in Follow-up of Patients Treated for CIN2+ Lesions

L. Mariani, P. Cristoforoni, S. Costa, 2016, Journal of Cancer.

Extending Human Papillomavirus (HPV) vaccination beyond female adolescents and after treatment for high grade CIN: the Italian HPV Study Group (IHSG) review and position paper.

L. Mariani, P. Cristoforoni, S. Costa, 2020, European review for medical and pharmacological sciences.

[HPV vaccination: not only female adolescents and not only prophylactic. Review and position paper of the Italian HPV Study Group (IHSG)].

L. Mariani, P. Cristoforoni, S. Costa, 2019, Minerva ginecologica.

Relationship of Up-Regulation of 67-kd Laminin Receptor to Grade of Cervical Intraepithelial Neoplasia and to High-Risk HPV Types and Prognosis in Cervical Cancer

L. Mariani, D. Santini, S. Syrjänen, 2006, Acta Cytologica.

E6/E7 mRNA testing for human papilloma virus-induced high-grade cervical intraepithelial disease (CIN2/CIN3): a promising perspective

L. Mariani, P. Cristoforoni, S. Costa, 2015, Ecancermedicalscience.

The predictive value of human papillomavirus testing for the outcome of patients conservatively treated for stage IA squamous cell cervical carcinoma.

D. Santini, S. Costa, M. Sideri, 2015, Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology.

Disease persistence in patients with cervical intraepithelial neoplasia undergoing electrosurgical conization.

D. Santini, S. Costa, P. Cristiani, 2002, Gynecologic oncology.

Time to viral clearance after successful conservative treatment for high-risk HPV-infected high-grade cervical intraepithelial neoplasia and early invasive squamous cervical carcinoma.

S. Costa, M. Landini, S. Ferretti, 2016, Diagnostic microbiology and infectious disease.

Factors predicting the outcome of conservatively treated adenocarcinoma in situ of the uterine cervix: an analysis of 166 cases.

D. Santini, S. Syrjänen, K. Syrjänen, 2012, Gynecologic oncology.

Survivin as a marker of cervical intraepithelial neoplasia and high-risk human papillomavirus and a predictor of virus clearance and prognosis in cervical cancer.

L. Mariani, D. Santini, S. Syrjänen, 2005, American journal of clinical pathology.

Co-factors of high-risk human papillomavirus infections display unique profiles in incident CIN1, CIN2 and CIN3

S. Tatti, A. Longatto-Filho, S. Syrjänen, 2011, International journal of STD & AIDS.

Down-regulated nucleoside diphosphate kinase nm23-H1 expression is unrelated to high-risk human papillomavirus but associated with progression of cervical intraepithelial neoplasia and unfavourable prognosis in cervical cancer

L. Mariani, D. Santini, K. Syrjänen, 2006, Journal of Clinical Pathology.

p300 Expression is Related to High-risk Human Papillomavirus Infections and Severity of Cervical Intraepithelial Neoplasia But Not to Viral or Disease Outcomes in a Longitudinal Setting

S. Tatti, A. Longatto-Filho, S. Syrjänen, 2010, International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists.

HPV-DNA testing for cervical cancer precursors: from evidence to clinical practice

L. Mariani, P. Cristoforoni, S. Costa, 2012, Ecancermedicalscience.

Upregulation of nuclear factor‐κB (NF‐κB) is related to the grade of cervical intraepithelial neoplasia, but is not an independent predictor of high‐risk human papillomavirus or disease outcome in cervical cancer

L. Mariani, D. Santini, S. Syrjänen, 2006 .

Immunosuppressive cytokine Interleukin-10 (IL-10) is up-regulated in high-grade CIN but not associated with high-risk human papillomavirus (HPV) at baseline, outcomes of HR-HPV infections or incident CIN in the LAMS cohort

S. Tatti, A. Longatto-Filho, S. Syrjänen, 2009, Virchows Archiv.

Expression of cell-cycle-associated proteins pRB2/p130 and p27kip in vulvar squamous cell carcinomas.

C. Cinti, A. Giordano, D. Santini, 2001, Human pathology.

Combined Pap Smear, Cervicography and HPV DNA Testing in the Detection of Cervical Intraepithelial Neoplasia and Cancer

K. Syrjänen, A. Zamparelli, A. Bovicelli, 2000, Acta Cytologica.

CD44 isoform 6 (CD44v6) is a prognostic indicator of the response to neoadjuvant chemotherapy in cervical carcinoma.

D. Santini, S. Syrjänen, P. Lipponen, 2001, Gynecologic oncology.

Search for herpes simplex virus 2 and human papillomavirus genetic expression in vulvar neoplasia.

L. Aurelian, S. Costa, A. Rotola, 1990, The Journal of reproductive medicine.

Hormonal Contraceptives and the Length of Their Use Are Not Independent Risk Factors for High-Risk HPV Infections or High-Grade CIN

S. Tatti, A. Longatto-Filho, S. Syrjänen, 2010, Gynecologic and Obstetric Investigation.

Follow-up of screening patients conservatively treated for cervical intraepithelial neoplasia grade 2-3.

S. Costa, M. Manfredi, F. Falcini, 2007, European journal of obstetrics, gynecology, and reproductive biology.

Cervicography and HPV DNA testing as triage criteria for patients with abnormal pap smear.

S. Costa, M. Sideri, L. Spinaci, 1998, Gynecologic oncology.

Disruption of HPV 16 E1 and E2 genes in precancerous cervical lesions.

E. Leo, S. Costa, M. Zerbini, 2009, Journal of virological methods.

Does Microcolposcopy Protect Patients with CIN and Unsatisfactory Colposcopy from the Risk of Incomplete Excision of Disease at the Time of Conization?

D. Santini, A. Bovicelli, S. Costa, 2002, Journal of lower genital tract disease.

Comparing PAP smear cytology, aided visual inspection, screening colposcopy, cervicography and HPV testing as optional screening tools in Latin America. Study design and baseline data of the LAMS study.

S. Tatti, A. Longatto-Filho, S. Syrjänen, 2005, Anticancer research.

Evaluation of visual inspection with acetic acid (VIA), Lugol's iodine (VILI), cervical cytology and HPV testing as cervical screening tools in Latin America. This report refers to partial results from the LAMS (Latin AMerican Screening) study.

S. Tatti, A. Longatto-Filho, S. Syrjänen, 2006, Journal of medical screening.

Aberrant expression of VEGF-C is related to grade of cervical intraepithelial neoplasia (CIN) and high risk HPV, but does not predict virus clearance after treatment of CIN or prognosis of cervical cancer

D. Santini, K. Syrjänen, P. Di Bonito, 2006, Journal of Clinical Pathology.

Presurgical assessment and therapy of microinvasive carcinoma of the cervix.

L. Martellini, G. Martinelli, S. Costa, 1995, Gynecologic oncology.

Colposcopy: A Direct Oral Microscopy for Oral Cancer and Precancer

Prashanth Panta, S. Costa, 2019 .

Independent determinants of inaccuracy of colposcopically directed punch biopsy of the cervix.

D. Santini, S. Costa, P. Cristiani, 2003, Gynecologic oncology.

Activation of the ERK/MAP kinase pathway in cervical intraepithelial neoplasia is related to grade of the lesion but not to high-risk human papillomavirus, virus clearance, or prognosis in cervical cancer.

D. Santini, K. Syrjänen, M. Branca, 2004, American journal of clinical pathology.

Molecular analysis of HPV 16 E6I/E6II spliced mRNAs and correlation with the viral physical state and the grade of the cervical lesion

E. Leo, S. Costa, M. Zerbini, 2009, Journal of medical virology.

Follow-up Study of Patients With Cervical Intraepithelial Neoplasia Grade 1 Overexpressing p 16 Ink 4 a

P. Monini, S. Costa, G. Barillari, 2013 .

Longitudinal outcomes of high-risk human papillomavirus (HPV) infections as competing-risks events following cervical HPV test at baseline visit in the NIS-LAMS cohort.

S. Tatti, A. Longatto-Filho, S. Syrjänen, 2012, European journal of gynaecological oncology.

ATL

P. Monini, S. Costa, G. Barillari, 2013, International Journal of Gynecologic Cancer.

Population-based frequency assessment of HPV-induced lesions in patients with borderline Pap tests in the Emilia-Romagna Region: the PATER study

D. Santini, E. Leo, S. Costa, 2011, Current medical research and opinion.

Human papillomavirus DNA and Pap tests: the need for cotesting in opportunistic setting during the transition time.

L. Mariani, P. Cristoforoni, S. Costa, 2013, Journal of lower genital tract disease.

Speculoscopy for Triage of Patients with an Abnormal Pap Smear: Data from the GISPE Study

K. Syrjänen, A. Zamparelli, A. Bovicelli, 2000, Journal of lower genital tract disease.

Immunological status to Epstein-Barr virus and cytomegalovirus in patients with genital condylomata

S. Costa, M. Zerbini, G. Gentilomi, 1989, European Journal of Epidemiology.

Assessment of risk factors and human papillomavirus (HPV) related pathogenetic mechanisms of CIN in HIV-positive and HIV-negative women. Study design and baseline data of the HPV-PathogenISS study.

L. Mariani, D. Santini, K. Syrjänen, 2004, European journal of gynaecological oncology.

Improving Laboratory Efficiency by Automation of Preanalytic Processing of ThinPrep Specimens for Real-Time PCR High-Risk HPV Testing

Maria Paola Landini, Daniela Barbieri, Simona Venturoli, 2016, Journal of laboratory automation.

Comparison of Abbott RealTime High Risk HPV and Hybrid Capture 2 for the detection of high-risk HPV DNA in a referral population setting.

D. Santini, E. Leo, S. Costa, 2012, Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology.

An Online Quality Assurance Program for Colposcopy in a Population-Based Cervical Screening Setting in Italy: Results on Colposcopic Impression

S. Costa, M. Sideri, P. Cristiani, 2014, Journal of lower genital tract disease.