N. McCarthy

发表

Apoptosis in the development of the immune system: Growth factors, clonal selection and bcl-2

Gwyn T. Williams, N. McCarthy, Christopher A. Smith, 1992, Cancer and Metastasis Reviews.

The Epstein-Barr virus gene BHRF1, a homologue of the cellular oncogene Bcl-2, inhibits apoptosis induced by gamma radiation and chemotherapeutic drugs.

G. Williams, N. McCarthy, S. Hazlewood, 1996, Advances in experimental medicine and biology.

Time to Change

N. McCarthy, A. Whyte, 2017 .

Epigenetics: Histone modification

N. McCarthy, 2013, Nature Reviews Cancer.

Interferon-gamma induces Fas trafficking and sensitization to apoptosis in vascular smooth muscle cells via a PI3K- and Akt-dependent mechanism.

T. Littlewood, M. Bennett, G. Tellides, 2006, The American journal of pathology.

An Introduction to Vascular Biology: The regulation of vascular smooth muscle cell apoptosis

M. Bennett, N. McCarthy, 2002 .

Autophagy: Tumour or death?

N. McCarthy, 2007, Nature Reviews Cancer.

Childhood cancer: A chilling conclusion

N. McCarthy, 2005, Nature Reviews Cancer.

Cell death: ..and a nice Chianti

N. McCarthy, 2008, Nature Reviews Cancer.

Tumour heterogeneity: The cancer kaleidoscope

N. McCarthy, 2014, Nature Reviews Cancer.

Immunotherapy: Self-improvement

N. McCarthy, 2004, Nature Reviews Cancer.

Metastasis: Route master

N. McCarthy, 2009, Nature Reviews Cancer.

Tumour heterogeneity: Darwin's finches

N. McCarthy, 2012, Nature Reviews Cancer.

Pharmacodynamics: A new model

N. McCarthy, 2006, Nature Reviews Cancer.

Tumour microenvironment: Inside moving out

N. McCarthy, 2007, Nature Reviews Cancer.

Microenvironment: Enforced compliance

N. McCarthy, 2012, Nature Reviews Cancer.

Insertional Mutagenesis: Flip'in beautiful

N. McCarthy, 2009, Nature Reviews Cancer.

Tumorigenesis: (H)IFs and buts

N. McCarthy, 2005, Nature Reviews Cancer.

drICE is an essential caspase required for apoptotic activity in Drosophila cells

A. Fraser, G. Evan, N. McCarthy, 1997, The EMBO journal.

Tumorigenesis: WNT branches out

N. McCarthy, 2013, Nature Reviews Cancer.

Mouse models: Of mice and men

N. McCarthy, 2012, Nature Reviews Cancer.

Cancer models: Getting it right

N. McCarthy, 2013, Nature Reviews Cancer.

Rapamycin inhibits human in stent restenosis vascular smooth muscle cells independently of pRB phosphorylation and p53.

M. Bennett, N. McCarthy, D. Rosner, 2005, Cardiovascular research.

Therapeutics: Targeting an oncometabolite

N. McCarthy, 2013, Nature Reviews Cancer.

To have and to hold

N. McCarthy, 2013, Nature Reviews Cancer.

Tumour microenvironment: More than just a mutagen

N. McCarthy, 2014, Nature Reviews Cancer.

Metastasis: ADORA(2B)tion

N. McCarthy, 2013, Nature Reviews Cancer.

Bladder cancer: Seemingly similar

N. McCarthy, 2014, Nature Reviews Cancer.

Early detection: Making an early mark?

N. McCarthy, 2004, Nature Reviews Cancer.

Breast cancer: Hypoxia and XBP1S

N. McCarthy, 2014, Nature Reviews Cancer.

Tumorigenesis: Megaphone MYC

N. McCarthy, 2012, Nature Reviews Cancer.

Drug resistance: Making a point

N. McCarthy, 2014, Nature Reviews Cancer.

Breast cancer: NOTCH and MAST are rearranged, but rarely

N. McCarthy, 2011, Nature Reviews Cancer.

Genomics: The great pretenders

N. McCarthy, 2012, Nature Reviews Cancer.

Tumorigenesis: Alternative view

N. McCarthy, 2007, Nature Reviews Cancer.

Metastasis: Self-renewal migrates onwards

N. McCarthy, 2010, Nature Reviews Cancer.

Old dog, new tricks

N. McCarthy, 2010, Nature Reviews Cancer.

Isolation of genes controlling apoptosis through their effects on cell survival.

M. Mourtada-Maarabouni, F. Farzaneh, Vanessa L. Hedge, 2006, Gene therapy & molecular biology.

The opposing roles of the Akt and c-Myc signalling pathways in survival from CD95-mediated apoptosis

G. Evan, J. Rohn, B. Burgering, 1998, Oncogene.

Oncolytic viruses: Export license

N. McCarthy, 2005, Nature Reviews Cancer.

Apoptosis: final control point in cell biology.

C. Smith, G. Williams, N. McCarthy, 1992, Trends in cell biology.

Leukaemia: A provoking end?

N. McCarthy, 2008, Nature Reviews Cancer.

Sharing the actin' limelight: Visualization of actin filaments in non-muscle cells

N. McCarthy, 2010 .

Therapeutics: Embracing instability

N. McCarthy, 2013, Nature Reviews Cancer.

Tumorigenesis: Oncogene detox programme

N. McCarthy, 2011, Nature Reviews Cancer.

Controllable genetic manipulation of apoptosis of cells in culture

G. Evan, T. Littlewood, S. Pelengaris, 2004, Cytotechnology.

Inhibition of Ced-3/ICE-related Proteases Does Not Prevent Cell Death Induced by Oncogenes, DNA Damage, or the Bcl-2 Homologue Bak

G. Evan, C. Gilbert, N. McCarthy, 1997, The Journal of cell biology.

Rhabdomyosarcoma: Flexibility could be important

N. McCarthy, 2014, Nature Reviews Cancer.

Autophagy: Surviving the tumour suppressor

N. McCarthy, 2007, Nature Reviews Molecular Cell Biology.

Tumorigenesis: Innate response

N. McCarthy, 2007, Nature Reviews Cancer.

Therapy: Through the barricades

N. McCarthy, 2006, Nature Reviews Cancer.

Tumour supressor: Benign association

N. McCarthy, 2004, Nature Reviews Cancer.

Death defying: Apoptosis and cancer

N. McCarthy, 2006 .

Tumour suppressors: Keeping Trim

N. McCarthy, 2008, Nature Reviews Cancer.

Angiogenesis: Blood born killer?

N. McCarthy, 2008, Nature Reviews Cancer.

Chromothripsis: Towards a mechanism

N. McCarthy, 2012, Nature Reviews Cancer.

Prostate cancer: Understanding why

N. McCarthy, 2013, Nature Reviews Cancer.

Protein kinases: REDD or dead?

N. McCarthy, 2004, Nature Reviews Cancer.

A growing concern

N. McCarthy, 2014, Nature Reviews Cancer.

A sense-abl response?

N. McCarthy, L. Brown, 1997, Nature.

Metabolism: Room to breathe

N. McCarthy, 2009, Nature Reviews Cancer.

Mathematical models: Two or three is better than one

N. McCarthy, 2013, Nature Reviews Cancer.

Angiogenesis: A complex picture

N. McCarthy, 2004, Nature Reviews Cancer.

Not as sunny as advertised

N. McCarthy, 2013, Nature Reviews Cancer.

Inflammation: Well connected

N. McCarthy, 2005, Nature Reviews Cancer.

Tumorigenesis: All together now

N. McCarthy, 2012, Nature Reviews Cancer.

Mitochondria: Getting together

N. McCarthy, 2012, Nature Reviews Molecular Cell Biology.

Metastasis: Moved to act

N. McCarthy, 2009, Nature Reviews Cancer.

Evolution: Deep down

N. McCarthy, 2008, Nature Reviews Cancer.

Signalling: REX rules

N. McCarthy, 2011, Nature Reviews Cancer.

Teaming up for transformation: Oncogene cooperation

N. McCarthy, 2006 .

Metabolism: Haem is where the heart is

N. McCarthy, 2011, Nature Reviews Cancer.

Apoptosis induced by cancer chemotherapeutic drugs and its genetic suppression

N. McCarthy, 1994 .

Retroviral insertional mutagenesis implicates E3 ubiquitin ligase RNF168 in the control of cell proliferation and survival

F. Farzaneh, Gwyn T. Williams, M. Pickard, 2017, Bioscience reports.

Expression profiling: Join the dots...find the bigger picture

N. McCarthy, 2006, Nature Reviews Cancer.

Apoptotic proteins. p53 and c-myc related pathways.

N. McCarthy, J. Mercer, M. Bennett, 2001, Cardiology clinics.

THE INTEGRATED CONTROL OF CELL PROLIFERATION AND CELL VIABILITY

G. Evan, T. Littlewood, D. Hancock, 1996 .

Dual direction CRISPR transcriptional regulation screening uncovers gene networks driving drug resistance

S. Lawo, C. le Sage, N. McCarthy, 2017, Scientific Reports.

Increasing the performance of pooled CRISPR–Cas9 drop-out screening

Jonathan D. Moore, Benedict C. S. Cross, Steffen Lawo, 2016, Scientific Reports.

Genetics: ALK takes the rap

N. McCarthy, 2008, Nature Reviews Cancer.

Cell Recognition of Apoptotic Cells

Gwyn T. Williams, N. McCarthy, Christopher A. Smith, 1993 .

Cancer: Small losses, big gains with microRNAs

N. McCarthy, 2010, Nature Reviews Genetics.

Metabonomics study of the effects of single copy mutant KRAS in the presence or absence of WT allele using human HCT116 isogenic cell lines

K. Veselkov, H. Keun, N. McCarthy, 2021, Metabolomics.

Metabolic characterization of colorectal cancer cells harbouring different KRAS mutations in codon 12, 13, 61 and 146 using human SW48 isogenic cell lines

K. Veselkov, H. Keun, N. McCarthy, 2020, Metabolomics.

Genomics: A broad brush

N. McCarthy, 2010, Nature Reviews Cancer.

Tumour homeostasis: Newton's third law

N. McCarthy, 2005, Nature Reviews Cancer.

15 Methods for Detecting and Quantifying Apoptosis

G. Evan, N. McCarthy, 1997 .

MicroRNA: Friend or foe?

N. McCarthy, 2005, Nature Reviews Cancer.

Leukaemia: Wandering downstream

N. McCarthy, 2006, Nature Reviews Cancer.

Chemotherapeutics: Lethal and resistant partners

N. McCarthy, 2007, Nature Reviews Cancer.

Genetics: A numbers game

N. McCarthy, 2008, Nature Reviews Cancer.

Breast cancer: The X factor

N. McCarthy, 2006, Nature Reviews Cancer.

Metastasis: SIX1 of the best

N. McCarthy, 2012, Nature Reviews Cancer.

Neuroblastoma: The right type of ALK

N. McCarthy, 2011, Nature Reviews Cancer.

Aneuploidy: Lack of a full set is damaging

N. McCarthy, 2011, Nature Reviews Cancer.

Autophagy: Limiting factors

N. McCarthy, 2011, Nature Reviews Cancer.

Biochemistry of cell death

A. Fraser, G. Evan, N. McCarthy, 1996, Current Opinion in Neurobiology.

Dual direction CRISPR transcriptional regulation screening uncovers gene networks driving drug resistance

Syed Asad Rahman, Annette S. Little, S. Lawo, 2017, Scientific Reports.

Sequencing: CpG islands and 5-hydroxymethylcytosine

N. McCarthy, Nicola McCarthy, 2012, Nature Reviews Cancer.

Cell death: 1+1≠2

N. McCarthy, 2012, Nature Reviews Cancer.

Metabolism: Unmasking an oncometabolite

N. McCarthy, 2012, Nature Reviews Cancer.

Tumour microenvironment: Losing your SPARC

N. McCarthy, 2013, Nature Reviews Cancer.

Doubling up?

N. McCarthy, 2012, Nature Reviews Cancer.

Mouse models: Role reversal

N. McCarthy, 2008, Nature Reviews. Cancer.

Anticancer drugs: Targeting menin

N. McCarthy, 2012, Nature reviews. Drug discovery.

Tumour suppressors: Super suppressor

N. McCarthy, 2004, Nature Reviews Cancer.

Tumorigenesis: Intricate insights

N. McCarthy, 2006, Nature Reviews. Cancer.

What's a girl to do?

N. McCarthy, 2012, Nature Reviews Cancer.

Tumorigenesis: Two-faced

N. McCarthy, 2008, Nature Reviews Cancer.

Chromatin remodelling: Looking vulnerable

N. McCarthy, 2014, Nature Reviews Cancer.

Metastasis: Influencing bad behaviour

N. McCarthy, 2009, Nature Reviews Cancer.

Tumour suppressors: Motoring on down

N. McCarthy, 2008, Nature Reviews Cancer.

DNA repair. A sense-abl response?

N. McCarthy, L. Brown, 1997, Nature.

Anticancer drugs: Collusion

N. McCarthy, 2007, Nature Reviews Drug Discovery.

Licensed to cause chaos

N. McCarthy, 2007, Nature Reviews Cancer.

Cancer stem cells: Tracing clones

N. McCarthy, 2012, Nature Reviews Cancer.

Therapeutics: A positive defect

N. McCarthy, 2005, Nature Reviews Cancer.

Metastasis: A new protector?

N. McCarthy, 2012, Nature Reviews Cancer.

Going up

Nicola McCarthy, N. McCarthy, 2020, Nature Reviews Cancer.

Bladder cancer: Finding the origin

N. McCarthy, 2014, Nature Reviews. Cancer.

Epigenetics: The long view

N. McCarthy, 2013, Nature Reviews Cancer.

Gene therapy: Means to an end

N. McCarthy, 2004, Nature Reviews. Cancer.

A Medium-Throughput Single Cell CRISPR-Cas9 Assay to Assess Gene Essentiality

J. Moore, R. Copeland, A. Grassian, 2015, Biological Procedures Online.

Therapeutics: Histone eviction

N. McCarthy, 2013, Nature Reviews Cancer.

CHAPTER 1 – An Introduction to Apoptosis

Gwyn T. Williams, N. McCarthy, Christopher A. Smith, 1993 .

Therapeutics: Smac it to them!

N. McCarthy, 2008, Nature Reviews Cancer.

Does the gender of the researcher or review author matter?

N. McCarthy, E. Hutchinson, Sarah E. Seton-Rogers, 2006, Nature reviews. Cancer.

Progress in Oncology 2001

N. McCarthy, 2003 .

Lung cancer: Overcoming crizotinib resistance

N. McCarthy, 2014, Nature Reviews Cancer.

Tumorigenesis: An original beginning

N. McCarthy, 2004, Nature Reviews. Cancer.

Microenvironment: A disturbed background

N. McCarthy, 2007, Nature Reviews Cancer.

Metastasis: Leaky effect

N. McCarthy, 2012, Nature Reviews Cancer.

Methods for detecting and quantifying apoptosis.

G. Evan, N. McCarthy, 1998, Current topics in developmental biology.

Melanoma: Directed therapy

N. McCarthy, 2013, Nature Reviews. Cancer.

Anticancer drugs: Now get out of that...

N. McCarthy, 2011, Nature reviews. Drug discovery.

Leukaemia: Now get out of that...

N. McCarthy, 2011, Nature Reviews. Cancer.

Immunotherapy: Adapt and survive

N. McCarthy, 2012, Nature Reviews. Cancer.

Senescence: Without SKP2

N. McCarthy, 2010, Nature Reviews. Cancer.

Cancer biology: Motion capture

N. McCarthy, 2010, Nature Reviews Molecular Cell Biology.

Metastasis: Motion capture

N. McCarthy, 2010, Nature Reviews Cancer.

JUMP Cell Painting dataset: morphological impact of 136,000 chemical and genetic perturbations

Anne E Carpenter, Lewis H. Mervin, Patrick W. Faloon, 2023, bioRxiv.

Senescence: Arrest me!

N. McCarthy, 2007, Nature Reviews Cancer.

Leukaemia: Top-NOTCH

N. McCarthy, 2006, Nature Reviews. Cancer.

Signalling: Structural survey

N. McCarthy, 2008, Nature Reviews Cancer.

Tumour heterogeneity: Darwin's finches

N. McCarthy, 2012, Nature Reviews Cancer.

Genetics: Bespoke mutations

N. McCarthy, 2013, Nature Reviews. Cancer.

Signalling: Wild type and mutant combine

N. McCarthy, 2012, Nature Reviews Cancer.

Metabolism: Mutant BRAF feels the burn

N. McCarthy, 2015, Nature Reviews Cancer.

Signalling: A change of state leads to rewiring

N. McCarthy, 2013, Nature Reviews Cancer.

Metabolism: MYC clocks on

N. McCarthy, 2015, Nature Reviews Cancer.

Prostate cancer: Studying the classics

N. McCarthy, 2011, Nature Reviews Cancer.

Feed a cold, starve a tumour

N. McCarthy, 2015, Nature Reviews Cancer.

Metabolism: Feed a cold, starve a tumour

N. McCarthy, 2014, Nature Reviews Cancer.

Tumorigenesis: Divining forks for developing tumours

N. McCarthy, 2004, Nature Reviews Cancer.

Tumour microenvironment: Target practice

N. McCarthy, 2011, Nature Reviews Cancer.

DNA damage: “Curiouser and curiouser!” cried Alice

N. McCarthy, 2010, Nature Reviews Cancer.

Mouse Models: Closer than you think

N. McCarthy, 2009, Nature Reviews Cancer.

Tumorigenesis: Replicating recurrence

N. McCarthy, 2009, Nature Reviews. Cancer.

Tumorigenesis: Them's the breaks kid

N. McCarthy, 2010, Nature Reviews Cancer.

Differential cyclin E expression in human in-stent stenosis smooth muscle cells identifies targets for selective anti-restenosis therapy.

P. Kirkpatrick, M. Bennett, N. McCarthy, 2003, Cardiovascular research.

Programmed Cell Death

G. Evan, N. McCarthy, 2002 .

Metabolism: Desaturated lipids required for survival

N. McCarthy, 2013, Nature Reviews Cancer.

Epigenetics: Worth another look?

N. McCarthy, 2011, Nature Reviews Cancer.

Understanding why

N. McCarthy, 2013, Nature Reviews Cancer.

Leukaemia: MLL makes friends and influences

N. McCarthy, 2010, Nature Reviews Cancer.

Tumour suppressors: Selective justice

N. McCarthy, 2011, Nature Reviews Cancer.

Tumour progression: Invasion suppressed

N. McCarthy, 2004, Nature Reviews Cancer.

Oncogene repression: CDYL and REST — a silent team

N. McCarthy, 2009, Nature Reviews Cancer.

Tumour profiling: Networking, protein style

Nicola McCarthy, N. McCarthy, 2007, Nature Reviews Cancer.

Tumour suppression: Ejector seat

N. McCarthy, 2010, Nature Reviews. Cancer.

An Introduction to Vascular Biology: The regulation of vascular smooth muscle cell apoptosis

M. Bennett, N. McCarthy, 2002 .

Well connected

N. McCarthy, Lewis Morgan, J. Ritchie, 2005 .