Hany E. A. Ahmed

发表

Methods for Computer‐aided Chemical Biology. Part 2: Evaluation of Compound Selectivity Using 2D Molecular Fingerprints

Jürgen Bajorath, Dagmar Stumpfe, Ingo Vogt, 2007, Chemical biology & drug design.

Methods for Computer‐aided Chemical Biology. Part 1: Design of a Benchmark System for the Evaluation of Compound Selectivity

Jürgen Bajorath, Dagmar Stumpfe, Ingo Vogt, 2007, Chemical biology & drug design.

Exploring structure–selectivity relationships of biogenic amine GPCR antagonists using similarity searching and dynamic compound mapping

Jürgen Bajorath, Jens Auer, Ingo Vogt, 2008, Molecular Diversity.

Methods for Computer‐Aided Chemical Biology. Part 5: Rationalizing the Selectivity of Cathepsin Inhibitors on the Basis of Molecular Fragments and Topological Feature Distributions

J. Bajorath, Hany E. A. Ahmed, 2009, Chemical biology & drug design.

Novel arylazothiazoles and arylazo[1,3,4]thiadiazoles as potential antimicrobial and anticancer agents: synthesis, molecular modeling, and biological screening

Anwar A. Deawaly, Saleh K. Ihmaid, Hany E. A. Ahmed, 2017, Medicinal Chemistry Research.

Novel triazolophthalazine-hydrazone hybrids as potential PCAF inhibitors: Design, synthesis, in vitro anticancer evaluation, apoptosis, and molecular docking studies.

Hany E. A. Ahmed, Hamada S. Abulkhair, Adel H. Ghiaty, 2020, Bioorganic chemistry.

Novel scaffold hopping of potent benzothiazole and isatin analogues linked to 1,2,3-triazole fragment that mimic quinazoline epidermal growth factor receptor inhibitors: Synthesis, antitumor and mechanistic analyses.

Saleh K. Ihmaid, Hany E. A. Ahmed, N. Rezki, 2020, Bioorganic chemistry.

Berberine Reduces Neurotoxicity Related to Nonalcoholic Steatohepatitis in Rats

J. Bajorath, Hany E. A. Ahmed, D. Ghareeb, 2015, Evidence-based complementary and alternative medicine : eCAM.

Developing lipophilic aromatic halogenated fused systems with specific ring orientations, leading to potent anticancer analogs and targeting the c-Src Kinase enzyme

Saleh K. Ihmaid, Hany E. A. Ahmed, A. Halawa, 2019, Journal of Molecular Structure.

Novel molecular discovery of promising amidine-based thiazole analogues as potent dual Matrix Metalloproteinase-2 and 9 inhibitors: Anticancer activity data with prominent cell cycle arrest and DNA fragmentation analysis effects.

Saleh K. Ihmaid, J. Bajorath, Hany E. A. Ahmed, 2020, Bioorganic chemistry.

Association of TM6SF2 rs58542926 with Hepatic and Extrahepatic Alterations in Chronic Hepatitis C Patients

G. Alvisi, Hany E. A. Ahmed, A. Calistri, 2021 .

In vitro and computational investigations of novel synthetic carboxamide-linked pyridopyrrolopyrimidines with potent activity as SARS-CoV-2-MPro inhibitors

Saleh K. Ihmaid, Hany E. A. Ahmed, H. Patel, 2022, RSC advances.

Design and Synthesis of Benzene Homologues Tethered with 1,2,4-Triazole and 1,3,4-Thiadiazole Motifs Revealing Dual MCF-7/HepG2 Cytotoxic Activity with Prominent Selectivity via Histone Demethylase LSD1 Inhibitory Effect

Saleh K. Ihmaid, Hany E. A. Ahmed, Mosa Alsehli, 2022, International journal of molecular sciences.

Synthesis, antimicrobial evaluation, DNA gyrase inhibition, and in silico pharmacokinetic studies of novel quinoline derivatives

Hany E. A. Ahmed, Khaled El-Adl, Hamada S. Abulkhair, 2020, Archiv der Pharmazie.

Introducing of potent cytotoxic novel 2-(aroylamino)cinnamamide derivatives against colon cancer mediated by dual apoptotic signal activation and oxidative stress.

Mostafa H. Ahmed, Hany E. A. Ahmed, M. Safo, 2020, Bioorganic chemistry.

Discovery of novel phthalimide analogs: Synthesis, antimicrobial and antitubercular screening with molecular docking studies

Hany E. A. Ahmed, Sahar Ahmed, T. H. Afifi, 2016, EXCLI journal.

Structure-activity relationships and molecular docking studies of chromene and chromene based azo chromophores: A novel series of potent antimicrobial and anticancer agents

J. Ilaš, Hany E. A. Ahmed, A. Abd-El-Aziz, 2017, EXCLI journal.

Antimicrobial and Antitumor Screening of Fluorescent 5,7‐Dihydroxy‐4‐Propyl‐2H‐Chromen‐2‐One Derivatives with Docking Studies

Hany E. A. Ahmed, A. Abd-El-Aziz, R. Bissessur, 2016 .

First example of Azo-Sulfa conjugated chromene moieties: Synthesis, characterization, antimicrobial assessment, docking simulation as potent class I histone deacetylase inhibitors and antitumor agents.

Hany E. A. Ahmed, R. M. Okasha, T. H. Afifi, 2019, Bioorganic chemistry.

Design, Synthesis, Cytotoxic Evaluation and Molecular Docking of New Fluoroquinazolinones as Potent Anticancer Agents with Dual EGFR Kinase and Tubulin Polymerization Inhibitory Effects

Hany E. A. Ahmed, S. Ibrahim, Sahar Ahmed, 2018, International journal of molecular sciences.

Synthesis, Modelling, and Anticonvulsant Studies of New Quinazolines Showing Three Highly Active Compounds with Low Toxicity and High Affinity to the GABA-A Receptor

Hany E. A. Ahmed, A. Asiri, Khaled El-Adl, 2017, Molecules.

Synthesis and screening of some new fluorinated quinazolinone–sulphonamide hybrids as anticancer agents

Hany E. A. Ahmed, A. Omar, M. Zayed, 2015 .

Design, synthesis, and biological evaluation studies of novel quinazolinone derivatives as anticonvulsant agents

Hany E. A. Ahmed, Khaled El-Adl, M. Zayed, 2013, Medicinal Chemistry Research.

Design, Synthesis and Cytotoxic Evaluation of Novel Chalcone Derivatives Bearing Triazolo[4,3-a]-quinoxaline Moieties as Potent Anticancer Agents with Dual EGFR Kinase and Tubulin Polymerization Inhibitory Effects

Hany E. A. Ahmed, A. Bayoumi, Ahmed Elmorsy, 2017, Molecules.

Design, synthesis, molecular docking of new lipophilic acetamide derivatives affording potential anticancer and antimicrobial agents.

Hany E. A. Ahmed, M. Elaasser, Sahar Ahmed, 2018, Bioorganic chemistry.

A novel dicationic ionic liquids encompassing pyridinium hydrazone-phenoxy conjugates as antimicrobial agents targeting diverse high resistant microbial strains

Hany E. A. Ahmed, M. Messali, N. Rezki, 2019, Journal of Molecular Liquids.

Targeted potent antimicrobial benzochromene-based analogues: Synthesis, computational studies, and inhibitory effect against 14α-Demethylase and DNA Gyrase.

Hany E. A. Ahmed, A. Halawa, Essam M. Eliwa, 2020, Bioorganic chemistry.

Synthesis, characterization, molecular modeling, and potential antimicrobial and anticancer activities of novel 2-aminoisoindoline-1,3-dione derivatives.

Mohamed A. Shaker, Hany E. A. Ahmed, H. Abdel-salam, 2016, Bioorganic chemistry.

Introducing novel potent anticancer agents of 1H-benzo[f]chromene scaffolds, targeting c-Src kinase enzyme with MDA-MB-231 cell line anti-invasion effect

Hany E. A. Ahmed, A. El-Agrody, A. Fouda, 2018, Journal of enzyme inhibition and medicinal chemistry.

Design, synthesis, and biological evaluation studies of novel quinazolinone derivatives as anticonvulsant agents

Hany E. A. Ahmed, Khaled El-Adl, M. Zayed, 2013, Medicinal Chemistry Research.

Novel 1,2,4‐triazole derivatives: Design, synthesis, anticancer evaluation, molecular docking, and pharmacokinetic profiling studies

Farag F. Sherbiny, Hany E. A. Ahmed, Hamada S. Abulkhair, 2020, Archiv der Pharmazie.

Synthesis, Biological Evaluation, and Molecular Docking of Novel Thiazoles and [1,3,4]Thiadiazoles Incorporating Sulfonamide Group as DHFR Inhibitors

Hany E. A. Ahmed, S. Riyadh, E. E. Habib, 2018, Chemistry & biodiversity.

Design of molecular hybrids of phthalimide-triazole agents with potent selective MCF-7/HepG2 cytotoxicity: Synthesis, EGFR inhibitory effect, and metabolic stability.

Hany E. A. Ahmed, S. Salama, A. Aljuhani, 2021, Bioorganic chemistry.

Design, Synthesis, and Docking Studies of 4H-Chromene and Chromene Based Azo Chromophores: A Novel Series of Potent Antimicrobial and Anticancer Agents

Hany E. A. Ahmed, A. Abd-El-Aziz, R. M. Okasha, 2017 .

The antimicrobial potential and pharmacokinetic profiles of novel quinoline-based scaffolds: synthesis and in silico mechanistic studies as dual DNA gyrase and DHFR inhibitors

Hany E. A. Ahmed, Khaled El-Adl, Hamada S. Abulkhair, 2021, New Journal of Chemistry.

S-substituted 2-mercaptoquinazolin-4(3H)-one and 4-ethylbenzensulfonamides act as potent and selective human carbonic anhydrase IX and XII inhibitors

C. Supuran, Hany E. A. Ahmed, M. Alanazi, 2020, Journal of enzyme inhibition and medicinal chemistry.

Exploring structure-activity relationship of S-substituted 2-mercaptoquinazolin-4(3H)-one including 4-ethylbenzenesulfonamides as human carbonic anhydrase inhibitors

C. Supuran, Hany E. A. Ahmed, A. Nocentini, 2020, Journal of enzyme inhibition and medicinal chemistry.

Antimicrobial screening and pharmacokinetic profiling of novel phenyl-[1,2,4]triazolo[4,3-a]quinoxaline analogues targeting DHFR and E. coli DNA gyrase B.

Farag F. Sherbiny, Hany E. A. Ahmed, T. H. Afifi, 2020, Bioorganic chemistry.

The rational design, synthesis, and antimicrobial investigation of 2-Amino-4-Methylthiazole analogues inhibitors of GlcN-6-P synthase.

Hany E. A. Ahmed, Sahar Ahmed, Hamada S. Abulkhair, 2020, Bioorganic chemistry.

Aegyoxepane: A New Oxepane Derivative from the Fungus Aspergillus aegyptiacus

Hany E. A. Ahmed, G. Mohamed, S. Ibrahim, 2016 .

The Design and Development of Potent Small Molecules as Anticancer Agents Targeting EGFR TK and Tubulin Polymerization

Hany E. A. Ahmed, M. Zayed, Saleh K Ihmaid, 2018, International journal of molecular sciences.

The anticancer and EGFR-TK/CDK-9 dual inhibitory potentials of new synthetic pyranopyrazole and pyrazolone derivatives: X-ray crystallography, in vitro, and in silico mechanistic investigations.

M. Abdelgawad, A. Musa, Sami I. Alzarea, 2023, Journal of biomolecular structure & dynamics.

In vivo‐ and in silico‐driven identification of novel synthetic quinoxalines as anticonvulsants and AMPA inhibitors

Memy H Hassan, Hany E. A. Ahmed, M. El-Zoghbi, 2021, Archiv der Pharmazie.

Rational design, synthesis, pharmacophore modeling, and docking studies for identification of novel potent DNA-PK inhibitors.

Hany E. A. Ahmed, H. Tarazi, Adeeb Al-Sheikh Ali, 2017, Bioorganic chemistry.

Discovery of triaromatic flexible agents bearing 1,2,3-Triazole with selective and potent anti-breast cancer activity and CDK9 inhibition supported by molecular dynamics

Hany E. A. Ahmed, S. Salama, A. Aljuhani, 2022, Journal of Molecular Structure.

Self Organizing Map-Based Classification of Cathepsin k and S Inhibitors with Different Selectivity Profiles Using Different Structural Molecular Fingerprints: Design and Application for Discovery of Novel Hits

Saleh K. Ihmaid, Hany E. A. Ahmed, Mohamed F. Zayed, 2016, Molecules.

Molecular pharmacophore selectivity studies, virtual screening, and in silico ADMET analysis of GPCR antagonists

Hany E. A. Ahmed, M. Zayed, Saleh K Ihmaid, 2015, Medicinal Chemistry Research.

Neuroprotective effect of berberine against environmental heavy metals-induced neurotoxicity and Alzheimer's-like disease in rats.

Hany E. A. Ahmed, D. Ghareeb, Hend M. Hussien, 2018, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

New ursane triterpenoids from Ficus pandurata and their binding affinity for human cannabinoid and opioid receptors

Hany E. A. Ahmed, G. Mohamed, S. Ibrahim, 2016, Archives of Pharmacal Research.

Pharmacological implications of ipriflavone against environmental metal–induced neurodegeneration and dementia in rats

Hany E. A. Ahmed, Samar R. Saleh, D. Ghareeb, 2021, Environmental Science and Pollution Research.

Effect of weeding status and tapping date on the yield of gum Arabic (Acacia Senegal) in Jigawa state, Nigeria

Hany E. A. Ahmed, S. Ahmed, M. S. Babura, 2017 .

A novel class of phenylpyrazolone-sulphonamides rigid synthetic anticancer molecules selectively inhibit the isoform IX of carbonic anhydrases guided by molecular docking and orbital analyses

Hany E. A. Ahmed, A. El-Agrody, Azizah M Malebari, 2023, Journal of biomolecular structure & dynamics.

1,2,4-Triazolo[4,3-c]quinazolines: a bioisosterism-guided approach towards the development of novel PCAF inhibitors with potential anticancer activity

Hany E. A. Ahmed, M. El-Zoghbi, Khaled El-Adl, 2021 .

Design, synthesis, molecular modelling and in vitro screening of monoamine oxidase inhibitory activities of novel quinazolyl hydrazine derivatives

Hany E. A. Ahmed, A. Amer, R. Ramsay, 2020, Royal Society Open Science.

Design and Evaluation of Bonded Atom Pair Descriptors

Jürgen Bajorath, Martin Vogt, Hany E. A. Ahmed, 2010, J. Chem. Inf. Model..

Hany E. A. Ahmed, A. Bayoumi, Ahmed Elmorsy, 2017, Molecules.

Development of Novel Class of Phenylpyrazolo[3,4-d]pyrimidine-Based Analogs with Potent Anticancer Activity and Multitarget Enzyme Inhibition Supported by Docking Studies

Hany E. A. Ahmed, Mohammed Almaghrabi, Mohamed M. Elsebaei, 2023, International journal of molecular sciences.

Synthesis, Docking, and Evaluation of Antimicrobial Activity of a New Series of Acyclo C-Nucleosides of 1, 2, 4-Triazolo[4, 3-a]quinoxaline Derivatives

Sherine N. Khattab, S. Senior, Hany E. A. Ahmed, 2016 .

N- and s-substituted Pyrazolopyrimidines: A promising new class of potent c-Src kinase inhibitors with prominent antitumor activity.

Hany E. A. Ahmed, A. Shati, M. Alfaifi, 2024, Bioorganic chemistry.