R. Sanishvili

发表

Ultrahigh resolution drug design I: Details of interactions in human aldose reductase–inhibitor complex at 0.66 Å

R E Cachau, B Chevrier, V. Lamour, 2004, Proteins.

In situ data collection and structure refinement from microcapillary protein crystallization.

Ruslan Sanishvili, Rustem F Ismagilov, Peter Kuhn, 2005, Journal of applied crystallography.

Structure of a HOIP/E2~ubiquitin complex reveals RBR E3 ligase mechanism and regulation

C. Ware, B. C. Lechtenberg, R. Sanishvili, 2015, Nature.

Crystal structure of the human β2 adrenergic G-protein-coupled receptor

M. Burghammer, S. Rasmussen, T. S. Kobilka, 2007, Nature.

Comparison of active sites of some microbial ribonucleases: structural basis for guanylic specificity.

K. Polyakov, J. Ševčík, R. Sanishvili, 1990, Trends in biochemical sciences.

Taking MAD to the extreme: ultrafast protein structure determination.

M A Walsh, A. Joachimiak, G. Evans, 1999, Acta crystallographica. Section D, Biological crystallography.

Integrating Structure, Bioinformatics, and Enzymology to Discover Function

J. Thornton, R. Laskowski, A. Edwards, 2003, Journal of Biological Chemistry.

The structure of iPLA2β reveals dimeric active sites and suggests mechanisms of regulation and localization

R. Gross, R. Sanishvili, S. Korolev, 2018, Nature Communications.

A 7 µm mini-beam improves diffraction data from small or imperfect crystals of macromolecules

Stephen Corcoran, Shenglan Xu, Michael Becker, 2008, Acta crystallographica. Section D, Biological crystallography.

Rastering strategy for screening and centring of microcrystal samples of human membrane proteins with a sub-10 µm size X-ray synchrotron beam

R. Stevens, V. Cherezov, Mark T. Griffith, 2009, Journal of The Royal Society Interface.

Structure Bases for Nucleotide Recognition by Guanyl-Specific Ribonucleases

A. Vagin, R. Sanishvili, A. Pavlovsky, 1988 .

Mechanism of proton transfer in class A β-lactamase catalysis and inhibition by avibactam

Fiona L. Kearns, H. Woodcock, M. Kemp, 2020, Proceedings of the National Academy of Sciences.

Ligand-Induced Proton Transfer and Low-Barrier Hydrogen Bond Revealed by X-ray Crystallography.

Jacqueline C. Hargis, A. Renslo, H. Woodcock, 2015, Journal of the American Chemical Society.

Model of the catalytic mechanism of human aldose reductase based on quantum chemical calculations

V. Lamour, A. Joachimiak, D. Moras, 2000 .

Molecular mechanism and structure of the Saccharomyces cerevisiae iron regulator Aft2

Chuan He, James R. Hinshaw, R. Sanishvili, 2014, Proceedings of the National Academy of Sciences.

Conformational Flexibility Enables Function of a BECN1 Region Essential for Starvation‐Mediated Autophagy

A. Ramanathan, Zhongyu Yang, R. Sanishvili, 2016, Biochemistry.

Crystallization of wild-type and mutant ferricytochromes c at low ionic strength: seeding technique and X-ray diffraction analysis.

K. Volz, E. Westbrook, R. Sanishvili, 1994, Acta crystallographica. Section D, Biological crystallography.

Examination of the mechanism of human brain aspartoacylase through the binding of an intermediate analogue.

R. Sanishvili, R. Viola, A. Pavlovsky, 2008, Biochemistry.

Parkinson's disease-associated mutations in the GTPase domain of LRRK2 impair its nucleotide-dependent conformational dynamics

Steven M. Johnson, M. Cookson, R. Nichols, 2019, The Journal of Biological Chemistry.

Rapid in situ X-ray position stabilization via extremum seeking feedback.

R. Fischetti, R. Sanishvili, C. Ogata, 2016, Journal of synchrotron radiation.

Structure and photoinduced electron transfer in exceptionally stable synthetic DNA hairpins with stilbenediether linkers

M. Wasielewski, A. Joachimiak, R. Letsinger, 1999 .

Identification of BECN1 and ATG14 Coiled-Coil Interface Residues That Are Important for Starvation-Induced Autophagy.

R. Sanishvili, S. Chakravarthy, S. Sinha, 2016, Biochemistry.

Mini-beam collimator enables microcrystallography experiments on standard beamlines.

Shenglan Xu, Michael Becker, Ruslan Sanishvili, 2009, Journal of synchrotron radiation.

Design and mechanism of tetrahydrothiophene-based γ-aminobutyric acid aminotransferase inactivators.

N. Kelleher, R. Wu, R. Sanishvili, 2015, Journal of the American Chemical Society.

The Structural Biology Center 19ID undulator beamline: facility specifications and protein crystallographic results.

Gwyndaf Evans, Ruslan Sanishvili, Edwin Westbrook, 2006, Journal of synchrotron radiation.

Polarization-dependence of anomalous scattering in brominated DNA and RNA molecules, and importance of crystal orientation in single- and multiple-wavelength anomalous diffraction phasing

G. Bricogne, R. Sanishvili, P. Pattison, 2007 .

The Active Site Sulfenic Acid Ligand in Nitrile Hydratases Can Function as a Nucleophile

R. Wu, R. Sanishvili, Dali Liu, 2014, Journal of the American Chemical Society.

Molecular basis of the antimutagenic activity of the house-cleaning inosine triphosphate pyrophosphatase RdgB from Escherichia coli.

Ruslan Sanishvili, N. Chirgadze, T. Skarina, 2007, Journal of molecular biology.

The structure of the yrdC gene product from Escherichia coli reveals a new fold and suggests a role in RNA binding

A. Joachimiak, M. Teplova, M. Egli, 2000, Protein science : a publication of the Protein Society.

The Structural Basis for Methylmalonic Aciduria

A. Joachimiak, C. Arrowsmith, V. Saridakis, 2004, Journal of Biological Chemistry.

The Structural Basis for Methylmalonic Aciduria THE CRYSTAL STRUCTURE OF ARCHAEAL ATP:COBALAMIN ADENOSYLTRANSFERASE*

A. Joachimiak, C. Arrowsmith, V. Saridakis, 2004 .

Mechanism of Inactivation of γ-Aminobutyric Acid Aminotransferase by (1S,3S)-3-Amino-4-difluoromethylene-1-cyclopentanoic Acid (CPP-115)

N. Kelleher, R. Wu, R. Sanishvili, 2015, Journal of the American Chemical Society.

PLP and GABA trigger GabR-mediated transcription regulation in Bacillus subtilis via external aldimine formation

G. Petsko, D. Ringe, R. Wu, 2017, Proceedings of the National Academy of Sciences.

X-ray crystallographic analysis of the hydration of A- and B-form DNA at atomic resolution.

M. Manoharan, A. Joachimiak, R. Miller, 1998, Biopolymers.

Mechanism of Inactivation of GABA Aminotransferase by (E)- and (Z)-(1S,3S)-3-Amino-4-fluoromethylenyl-1-cyclopentanoic Acid.

N. Kelleher, R. Wu, R. Sanishvili, 2015, ACS chemical biology.

Crystallographic analysis of a novel complex of actinomycin D bound to the DNA decamer CGATCGATCG.

A. Joachimiak, A. Wang, H. Robinson, 2001, Biochemistry.

Mechanisms of proton relay and product release by Class A β‐lactamase at ultrahigh resolution

Ruslan Sanishvili, Yu Chen, R. Sanishvili, 2018, The FEBS journal.

SIMBAD: a sequence-independent molecular-replacement pipeline

Martin Savko, Ronan M Keegan, Daniel J Rigden, 2017, Acta crystallographica. Section D, Structural biology.

The low ionic strength crystal structure of horse cytochrome c at 2.1 A resolution and comparison with its high ionic strength counterpart.

E. Margoliash, K. Volz, E. Westbrook, 1995, Structure.

Crystal structure of the human beta2 adrenergic G-protein-coupled receptor.

Manfred Burghammer, Ruslan Sanishvili, Robert F Fischetti, 2007, Nature.

Crystal structure of the hypothetical protein TA1238 from Thermoplasma acidophilum: A new type of helical super-bundle

A. Joachimiak, D. Christendat, R. Sanishvili, 2005, Journal of Structural and Functional Genomics.

Radiation damage in protein crystals is reduced with a micron-sized X-ray beam

Stephen Corcoran, Shenglan Xu, Stefan Vogt, 2011, Proceedings of the National Academy of Sciences.

Applications of X-Ray Micro-Beam for Data Collection.

Ruslan Sanishvili, Robert F Fischetti, R. Fischetti, 2017, Methods in molecular biology.

Targeting γ-Herpesvirus 68 Bcl-2-mediated Down-regulation of Autophagy*

R. Sanishvili, B. Levine, S. Sinha, 2014, The Journal of Biological Chemistry.

Structural and Biochemical Characterization of the Type II Fructose-1,6-bisphosphatase GlpX from Escherichia coli*

A. Joachimiak, T. Skarina, A. Savchenko, 2009, Journal of Biological Chemistry.

Crystal structure of the human b 2 adrenergic G-protein-coupled receptor

M. Burghammer, S. Rasmussen, T. S. Kobilka, 2007 .

A novel dimeric active site and regulation mechanism revealed by the crystal structure of iPLA2β

R. Gross, R. Sanishvili, S. Korolev, 2017, bioRxiv.

JBluIce-EPICS control system for macromolecular crystallography.

Sergey Stepanov, Mark Hilgart, Oleg Makarov, 2011, Acta crystallographica. Section D, Biological crystallography.

MAD data collection - current trends.

A. Joachimiak, G. Evans, R. Sanishvili, 1999, Acta crystallographica. Section D, Biological crystallography.

Micro‐Crystallography Developments at GM/CA‐CAT at the APS

Craig M. Ogata, Oleg Makarov, Stephen Corcoran, 2010 .

A revised 1.6 Å structure of the GTPase domain of the Parkinson’s disease-associated protein LRRK2 provides insights into mechanisms

Steven M. Johnson, M. Cookson, R. Nichols, 2019, bioRxiv.

Biochemical characterization and crystal structure determination of human heart short chain L-3-hydroxyacyl-CoA dehydrogenase provide insights into catalytic mechanism.

L. Banaszak, R. Sanishvili, A. Strauss, 1999, Biochemistry.

Using surface-bound rubidium ions for protein phasing.

A. Joachimiak, Z. Otwinowski, W. Minor, 2001, Acta crystallographica. Section D, Biological crystallography.

In Crystallo Posttranslational Modification Within a MauG/Pre–Methylamine Dehydrogenase Complex

C. Wilmot, V. Davidson, R. Sanishvili, 2010, Science.

Automated sample-scanning methods for radiation damage mitigation and diffraction-based centering of macromolecular crystals.

Michael Becker, Ruslan Sanishvili, Robert F Fischetti, 2011, Journal of synchrotron radiation.

A 7 m m mini-beam improves diffraction data from small or imperfect crystals of macromolecules

R. Sanishvili, Shenglan Xu, M. Becker, 2008 .

Fast fluorescence techniques for crystallography beamlines.

Michael Becker, Martin Caffrey, Mark Hilgart, 2011, Journal of applied crystallography.

SIMBAD: a sequence-independent molecular-replacement pipeline

D. Rigden, A. Lebedev, R. Keegan, 2018, Acta crystallographica. Section D, Structural biology.

The role of histidines 26 and 33 in the structural stabilization of cytochrome c.

R. Sanishvili, W. Qin, A. Schejter, 1995, Biochimica et biophysica acta.

Design and mechanism of tetrahydrothiophene-based γ-aminobutyric acid aminotransferase inactivators.

N. Kelleher, R. Wu, R. Sanishvili, 2015, Journal of the American Chemical Society.

Hexahydrated magnesium ions bind in the deep major groove and at the outer mouth of A-form nucleic acid duplexes.

A. Joachimiak, H. Robinson, R. Sanishvili, 2000, Nucleic acids research.

Crystal structure of Bacillus subtilis YckF: structural and functional evolution.

J. Watson, A. Joachimiak, F. Collart, 2004, Journal of structural biology.

Face-to-face and edge-to-face pi-pi interactions in a synthetic DNA hairpin with a stilbenediether linker.

M. Egli, V. Tereshko, R. Sanishvili, 2003, Journal of the American Chemical Society.

Tightly integrated single- and multi-crystal data collection strategy calculation and parallelized data processing in JBluIce beamline control system

Craig M. Ogata, Nicholas K. Sauter, Michael Becker, 2014, Journal of applied crystallography.