M. Chiano

发表

Phenome-wide association study using research participants’ self-reported data provides insight into the Th17 and IL-17 pathway

Li Li, Deepak K Rajpal, M. Nelson, 2017, PloS one.

The Extent and Impact of Variation in ADME Genes in Sub-Saharan African Populations

Faisal M. Fadlelmola, A. S. Gross, C. Adebamowo, 2020, bioRxiv.

Genetics plays a limited role in predicting chronic obstructive pulmonary disease treatment response and exacerbation.

P. S. St. Jean, D. Fraser, M. Chiano, 2021, Respiratory medicine.

Tobacco smoking and oestrogen replacement are associated with lower total and central fat in monozygotic twins

T. Spector, K. Samaras, L. Campbell, 1998, International Journal of Obesity.

The role of serum TGF-beta isoforms as potential markers of osteoporosis.

T. Spector, D. Grainger, M. Chiano, 1999, Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA.

A genome-wide search for linkage to asthma phenotypes in the genetics of asthma international network families: evidence for a major susceptibility locus on chromosome 2p

M. Pericak-Vance, J. Riley, J. Vance, 2006, European Journal of Human Genetics.

Klotho Gene Polymorphisms Associated With Bone Density of Aged Postmenopausal Women

T. Spector, Kozo Nakamura, S. Inoue, 2002, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Germline mutations of the BRCA1 gene in breast and ovarian cancer families provide evidence for a genotype–phenotype correlation

D. Clayton, D. Easton, S. Seal, 1995, Nature Genetics.

CEPH consortium Map of chromosome 9.

J. Haines, J. Attwood, J. Gusella, 1994, Genomics.

No genetic association detected with mepolizumab efficacy in severe asthma.

E. Bleecker, H. Ortega, S. Yancey, 2017, Respiratory medicine.

Homozygotes and heterozygotes for ciliary neurotrophic factor null alleles do not show earlier onset of Huntington's disease

D. Rubinsztein, D. Craufurd, J. Leggo, 1997, Neurology.

Genetic and Environmental Influences on Total-Body and Central Abdominal Fat: The Effect of Physical Activity in Female Twins

Paul Kelly, P. Kelly, K. Samaras, 1999, Annals of Internal Medicine.

Comparison of genome screens for two independent cohorts provides replication of suggestive linkage of bone mineral density to 3p21 and 1p36.

T. Spector, P. Sambrook, A. Bansal, 2003, American journal of human genetics.

A coding polymorphism in the CYSLT2 receptor with reduced affinity to LTD4 is associated with asthma.

M. Wagner, J. Vestbo, H. Sarau, 2004, Pharmacogenetics.

‘Sifting the significance from the data’ - the impact of high-throughput genomic technologies on human genetics and health care

J. Gallacher, C. Tyler-Smith, N. Craddock, 2012, Human Genomics.

Genetic control of the circulating concentration of transforming growth factor type beta1.

T. Spector, H. Snieder, D. Grainger, 1999, Human molecular genetics.

Identification of a novel asthma susceptibility gene on chromosome 1qter and its functional evaluation.

J. Vestbo, J. Riley, M. Wigglesworth, 2008, Human molecular genetics.

The Role of Serum TGF-β Isoforms as Potential Markers of Osteoporosis

T. Spector, D. Grainger, M. Chiano, 1999, Osteoporosis International.

Assessment of rosacea symptom severity by genome-wide association study and expression analysis highlights immuno-inflammatory and skin pigmentation genes

M. Ehm, D. Hinds, D. Rajpal, 2018, Human molecular genetics.

Common BRCA1 variants and susceptibility to breast and ovarian cancer in the general population.

D. Clayton, D. Easton, M. Stratton, 1997, Human molecular genetics.

Genotypic relative risks under ordered restriction

D. Clayton, M. Chiano, M.N. Chiano, 1998, Genetic epidemiology.

Novel association suggests multiple independent QTLs within chromosome 5q21–33 region control variation in total humans IgE levels

T. Spector, D. Strachan, Michel Galley, 2003, Genes and Immunity.

Absence of association of asporin polymorphisms and osteoarthritis susceptibility in US Caucasians.

R. Moskowitz, M. Hochberg, J. Jordan, 2008, Osteoarthritis and cartilage.

Genotypes at the GluR6 kainate receptor locus are associated with variation in the age of onset of Huntington disease.

G Norbury, D. Rubinsztein, D. Craufurd, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Evidence of association and linkage disequilibrium between a novel polymorphism in the transforming growth factor beta 1 gene and hip bone mineral density: a study of female twins.

T. Spector, H. Snieder, P. Smith, 2001, Rheumatology.

A Genome‐Screen of a Large Twin Cohort Reveals Linkage for Quantitative Ultrasound of the Calcaneus to 2q33–37 and 4q12–21

T. Spector, M. Langdown, M. Chiano, 2003, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Sib-TDT analysis of human TGF-beta1 gene single nucleotide polymorphisms in female twins: evidence for linkage and association with blood pressure at the codon 263 polymorphism

T. Spector, H. Snieder, M. Chiano, 2000 .

Genes Versus Environment: The relationship between dietary fat and total and central abdominal fat

T. Spector, K. Samaras, L. Campbell, 1998, Diabetes Care.

Large-scale genome-wide screen of female twin pairs confirms presence of QTLs for BMD at 1p36 and 3p21

T. Spector, M. Langdown, M. Chiano, 2002 .

A genome-wide search for linkage to asthma phenotypes in the genetics of asthma international network families: evidence for a major susceptibility locus on chromosome 2p

M. Pericak-Vance, J. Riley, J. Vance, 2007, European Journal of Human Genetics.

Bootstrapping in human genetic linkage

M. Chiano, J. Yates, M. N. CHIANO, 1994, Annals of human genetics.

Linkage detection under heterogeneity and the mixture problem

M. Chiano, J. Yates, 1995, Annals of Human Genetics.

Fine genetic mapping using haplotype analysis and the missing data problem

D G Clayton, D. Clayton, M. Chiano, 1998, Annals of human genetics.

Presymptomatic diagnosis of von Hippel-Lindau disease with flanking DNA markers.

D. Barton, J. Yates, M. Chiano, 1992, Journal of medical genetics.