J. Barker

发表

Phenome-wide association study using research participants’ self-reported data provides insight into the Th17 and IL-17 pathway

Li Li, Deepak K Rajpal, M. Nelson, 2017, PloS one.

Large scale meta-analysis characterizes genetic architecture for common psoriasis associated variants

James T. Elder, N. Eriksson, G. Abecasis, 2016, Nature Communications.

Genetic correlations among neuro-behavioral and immune-related phenotypes based on genome-wide association data

James T. Elder, H. Hakonarson, S. Grant, 2016, bioRxiv.

Sustained improvement in joint pain and nail symptoms with etanercept therapy in patients with moderate‐to‐severe psoriasis

J. Lambert, T. Luger, J. Barker, 2009, Journal of the European Academy of Dermatology and Venereology : JEADV.

European S3‐Guidelines on the systemic treatment of psoriasis vulgaris

L. Naldi, H. Hönigsmann, M. Hussain, 2009, Journal of the European Academy of Dermatology and Venereology : JEADV.

Biological therapies in the systemic management of psoriasis: International Consensus Conference

J. Saurat, S. Chimenti, J. Ortonne, 2004, The British journal of dermatology.

Genome-wide association study identiﬁes three novel susceptibility loci for severe Acne vulgaris

T. Spector, M. Weale, Sue Hood, 2022 .

Identification of fifteen new psoriasis susceptibility loci highlights the role of innate immunity

James T. Elder, C. Spencer, P. Deloukas, 2012, Nature Genetics.

Update on psoriasis immunopathogenesis and targeted immunotherapy

F. Capon, J. Barker, S. Mahil, 2015, Seminars in Immunopathology.

A synonymous SNP of the corneodesmosin gene leads to increased mRNA stability and demonstrates association with psoriasis across diverse ethnic groups.

Richard C Trembath, R. Trembath, D. Tillman, 2004, Human molecular genetics.

Mutations in the γ-secretase genes NCSTN, PSENEN, and PSEN1 underlie rare forms of hidradenitis suppurativa (acne inversa).

M. Simpson, R. Trembath, D. Dafou, 2012, The Journal of investigative dermatology.

A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1

Matti Pirinen, Peter Donnelly, Robert Plomin, 2010, Nature Genetics.

Exome-wide association study reveals novel psoriasis susceptibility locus at TNFSF15 and rare protective alleles in genes contributing to type I IFN signalling

James T. Elder, A. Peters, G. Abecasis, 2017, Human molecular genetics.

EndoPDI, a Novel Protein-disulfide Isomerase-like Protein That Is Preferentially Expressed in Endothelial Cells Acts as a Stress Survival Factor*

R. Poulsom, D. Creamer, J. Barker, 2003, Journal of Biological Chemistry.

Psoriasis and Genetics

M. Simpson, N. Dand, F. Capon, 2020, Acta dermato-venereologica.

Immunogenetics of psoriasis

J. Barker, 1998 .

Sequence variants in the genes for the interleukin-23 receptor (IL23R) and its ligand (IL12B) confer protection against psoriasis

Frank O. Nestle, Alexander Gutin, Christina Dunster, 2007, Human Genetics.

Psoriasis and its management

J. Barker, Catherine H. Smith, J. Barker, 2006, BMJ : British Medical Journal.

Marked synergism between tumor necrosis factor-alpha and interferon-gamma in regulation of keratinocyte-derived adhesion molecules and chemotactic factors.

V. Dixit, J. Barker, V. Sarma, 1990, The Journal of clinical investigation.

Effect of in vivo interleukin-1 on adhesion molecule expression in normal human skin.

D. Macdonald, J. Barker, R. Groves, 1992, The Journal of investigative dermatology.

Modulation of leucocyte adhesion molecules, a T‐cell chemotaxin (IL‐8) and a regulatory cytokine (TNF‐α) in allergic contact dermatitis (rhus dermatitis)

S. Kunkel, C. Griffiths, J. Barker, 1991, The British journal of dermatology.

The role of adhesion molecules, chemotactic factors, and cytokines in inflammatory and neoplastic skin disease--1990 update.

C. Griffiths, J. Barker, B. Nickoloff, 1990, The Journal of investigative dermatology.

Vascular cell adhesion molecule-1: expression in normal and diseased skin and regulation in vivo by interferon gamma.

D. Macdonald, J. Barker, R. Groves, 1993, Journal of the American Academy of Dermatology.

Psoriasis and cardiometabolic traits: modest association but distinct genetic architectures

James T. Elder, C. Gieger, F. Kronenberg, 2015, The Journal of investigative dermatology.

Analysis of the individual and aggregate genetic contributions of previously identified serine peptidase inhibitor Kazal type 5 (SPINK5), kallikrein-related peptidase 7 (KLK7), and filaggrin (FLG) polymorphisms to eczema risk.

C. Strobl, N. Klopp, T. Illig, 2008, The Journal of allergy and clinical immunology.

Genome-wide association study in frontal fibrosing alopecia identifies four susceptibility loci including HLA-B*07:02

Chrysanthi Ainali, Xavier Estivill, Alka Saxena, 2019, Nature Communications.

Establishing an Academic-Industrial Stratified Medicine Consortium: Psoriasis Stratification to Optimize Relevant Therapy.

M. Barnes, F. Nestle, A. Burden, 2015, The Journal of investigative dermatology.

Effects of biologic therapies on the severity of skin symptoms and quality of life in patients with plaque-type psoriasis: a meta-analysis.

K. Reich, C. Griffiths, J. Barker, 2007 .

A review of recent journal highlights

J. Barker, J. Barker, 2004 .

Does weight loss reduce the severity and incidence of psoriasis or psoriatic arthritis? A Critically Appraised Topic

J. Barker, C. Smith, S. Mahil, 2019, The British journal of dermatology.

A randomised placebo controlled trial of anakinra for treating pustular psoriasis: statistical analysis plan for stage two of the APRICOT trial

N. Reynolds, F. Capon, V. Cornelius, 2020, Trials.

Transition to ustekinumab in patients with moderate‐to‐severe psoriasis and inadequate response to methotrexate: a randomized clinical trial (TRANSIT)

S. Chimenti, J. Lambert, T. Luger, 2014, The British journal of dermatology.

One‐year safety and efficacy of ustekinumab and results of dose adjustment after switching from inadequate methotrexate treatment: the TRANSIT randomized trial in moderate‐to‐severe plaque psoriasis

S. Chimenti, J. Lambert, T. Luger, 2014, The British journal of dermatology.

A small population, randomised, placebo-controlled trial to determine the efficacy of anakinra in the treatment of pustular psoriasis: study protocol for the APRICOT trial

N. Reynolds, F. Capon, A. Pink, 2018, Trials.

Filaggrin loss‐of‐function mutations are associated with early‐onset eczema, eczema severity and transepidermal water loss at 3 months of age

C. Flohr, G. Lack, J. Barker, 2010, The British journal of dermatology.

Filaggrin mutations are a major predisposing factor in childhood-onset adult-persistent atopic dermatitis

R. Trembath, N. Reynolds, J. Barker, 2006 .

Psoriasis and cardiovascular disease: where is the risk?

J. Barker, Catherine H. Smith, C. Maybury, 2013, The Journal of investigative dermatology.

Infliximab for severe, treatment‐resistant psoriasis: a prospective, open‐label study

J. Barker, S. Bashir, A. Chew, 2006, The British journal of dermatology.

Successful treatment of severe psoriasis and psoriatic arthritis with adalimumab

A. Bennett, B. Kirkham, J. Barker, 2004, The British journal of dermatology.

Health Economic Assessment of Optimal Biological Treatment for Moderate-to-Severe Psoriasis

G. Girolomoni, J. Barker, H. Baker, 2021, Clinical Drug Investigation.

Tumour necrosis factor antagonist‐induced lupus: a Critically Appraised Topic

B. Kirkham, J. Barker, C. Smith, 2017, The British journal of dermatology.

Angiogenesis in psoriasis

D. Creamer, J. Barker, R. Bicknell, 2004, Angiogenesis.

Association of Clinical and Demographic Factors With the Severity of Palmoplantar Pustulosis

Kaspar Torz, S. Kõks, A. Burden, 2020, JAMA dermatology.

Comparison of Drug Discontinuation, Effectiveness, and Safety Between Clinical Trial Eligible and Ineligible Patients in BADBIR

A. Burden, C. Griffiths, M. Lunt, 2018, JAMA dermatology.

miR-146b Probably Assists miRNA-146a in the Suppression of Keratinocyte Proliferation and Inflammatory Responses in Psoriasis.

James T. Elder, C. Gieger, M. Weichenthal, 2017, The Journal of investigative dermatology.

Elevated expression and genetic association links the SOCS3 gene to atopic dermatitis.

J. Kere, M. Wickman, G. Pershagen, 2006, American journal of human genetics.

Genome-Wide Pathway Analysis Identifies Genetic Pathways Associated with Psoriasis.

D. Absher, R. Myers, J. Gelpí, 2016, The Journal of investigative dermatology.

Clinical characteristics including cardiovascular and metabolic risk factors in adolescents with psoriasis

A. Nybo Andersen, L. Skov, C. Zachariae, 2020, Journal of the European Academy of Dermatology and Venereology : JEADV.

Acne and telomere length. A new spectrum between senescence and apoptosis pathways

T. Spector, M. Mangino, A. Aviv, 2016 .

Meta-analysis of genome-wide studies of psoriasis susceptibility reveals linkage to chromosomes 6p21 and 4q28-q31 in Caucasian and Chinese Hans population.

James T. Elder, M. Iles, R. Trembath, 2004, The Journal of investigative dermatology.

Corneodesmosin (CDSN) gene association with psoriasis vulgaris in Caucasian but not in Japanese populations

S. Fisher, C. M. Lewis, H. Nakagawa, 2005, Clincal and Experimental Dermatology.

A Crohn's disease‐associated insertion polymorphism (3020insC) in the NOD2 gene is not associated with psoriasis vulgaris, palmo‐plantar pustular psoriasis or guttate psoriasis

C. Mathew, R. Trembath, A. Burden, 2003, Experimental dermatology.

Pathogenesis of Psoriasis

J. Barker, 1998, The Journal of dermatology.

Endothelial leucocyte adhesion molecule‐1 (ELAM‐1) expression in cutaneous inflammation

D. Macdonald, J. Barker, D. Haskard, 1991, The British journal of dermatology.

Psoriasis

C. Griffiths, J. Barker, J. Gudjonsson, 1986, The Lancet.

Placebo Response in Two Long-Term Randomized Psoriasis Studies that were Negative for Rosiglitazone

J. Barker, C. Ellis, D. Jayawardene, 2007, American journal of clinical dermatology.

Psoriasis as a systemic disease

J. Barker, 2008 .

The importance of disease associations and concomitant therapy for the long-term management of psoriasis patients

James T. Elder, J. Barker, U. Mrowietz, 2006, Archives of Dermatological Research.

Analysis of the individual and aggregate genetic contributions of previously identified SPINK 5 , KLK 7 and FLG polymorphisms to eczema risk

C. Strobl, N. Klopp, T. Illig, 2015 .

Assessment and management of methotrexate hepatotoxicity in psoriasis patients: report from a consensus conference to evaluate current practice and identify key questions toward optimizing methotrexate use in the clinic

Elizabeth J Horn, M. Lebwohl, E. Horn, 2011, Journal of the European Academy of Dermatology and Venereology : JEADV.

Polymorphisms in folate, pyrimidine, and purine metabolism are associated with efficacy and toxicity of methotrexate in psoriasis.

C. Lewis, J. Barker, Catherine H. Smith, 2007, The Journal of investigative dermatology.

Interleukin-36 promotes systemic Type-I IFN responses in severe forms of psoriasis

F. Ciccarelli, F. Capon, H. Young, 2019 .

CYP1A1 Enzymatic Activity Influences Skin Inflammation Via Regulation of the AHR Pathway

B. Stockinger, F. Nestle, P. Di Meglio, 2020, The Journal of investigative dermatology.

The tissue distribution of factor XIIIa positive cells

D. Macdonald, J. Barker, M. Price, 1993, Histopathology.

Influence of FLG loss-of-function mutations in host-microbe interactions during atopic skin inflammation.

J. Kere, D. Greco, S. Tsoka, 2022, Journal of dermatological science.

Tmem79/Matt is the matted mouse gene and is a predisposing gene for atopic dermatitis in human subjects

C. Gieger, G. Barton, A. Balmain, 2013, The Journal of allergy and clinical immunology.

Cross-phenotype association mapping of the MHC identifies genetic variants that differentiate psoriatic arthritis from psoriasis

A. Barton, M. Brown, M. Simpson, 2017, Annals of the rheumatic diseases.

Psoriasis: Aetiology and Pathogenesis

J. Barker, 2019 .

Genetic markers of treatment response to tumour necrosis factor‐α inhibitors in the treatment of psoriasis

J. Barker, C. Ryan, M. Allen, 2014, Clinical and experimental dermatology.

Anti‐E‐selectin is ineffective in the treatment of psoriasis: a randomized trial

C. Griffiths, C. Griffiths, J. Barker, 2002, The British journal of dermatology.

Clinical impact of antibodies against ustekinumab in psoriasis: an observational, cross-sectional, multicenter study.

R. Emsley, M. Barnes, K. Payne, 2020, The Journal of investigative dermatology.

Secukinumab for patients failing previous tumour necrosis factor‐α inhibitor therapy: results of a randomized open‐label study (SIGNATURE)

A. Finlay, A. Burden, C. Griffiths, 2020, The British journal of dermatology.

Cost-effectiveness of apremilast in moderate to severe psoriasis in the United Kingdom

A. Bewley, J. Barker, T. Tencer, 2018 .

Demographics and disease characteristics of patients with psoriasis enrolled in the British Association of Dermatologists Biologic Interventions Register

A. Burden, N. Reynolds, I. Iskandar, 2015, The British journal of dermatology.

Increased epidermal cell proliferation in normal human skin in vivo following local administration of interferon-gamma.

D. Macdonald, J. Barker, J. Goodlad, 1993, The American journal of pathology.

Adhesion molecule expression in polymorphic light eruption.

P. Norris, D. Macdonald, J. Barker, 1992, The Journal of investigative dermatology.

Distribution of intercellular‐adhesion molecule‐1 (ICAM‐1) and lymphocyte‐function‐associated antigen‐1 (LFA‐1) in epidermal tumours

D. Macdonald, J. Barker, M. Allen, 1990, Clinical and experimental dermatology.

The effect of in vivo interferon-gamma on the distribution of LFA-1 and ICAM-1 in normal human skin.

D. Macdonald, J. Barker, M. Allen, 1989, The Journal of investigative dermatology.

γ-Secretase mutations in hidradenitis suppurativa: new insights into disease pathogenesis.

M. Simpson, R. Trembath, A. Pink, 2013, The Journal of investigative dermatology.

Genetic variation in efflux transporters influences outcome to methotrexate therapy in patients with psoriasis.

S. Eyre, Jane Worthington, C. Griffiths, 2008, The Journal of investigative dermatology.

Keratinocyte expression of OKM5 antigen in inflammatory cutaneous disease

D. Macdonald, D. Macdonald, J. Barker, 1989, The British journal of dermatology.

Interferon-gamma activates co-ordinate transcription of HLA-DR, DQ, and DP genes in cultured keratinocytes and requires de novo protein synthesis.

K. Welsh, D. Macdonald, I. Leigh, 1990, The Journal of investigative dermatology.

Products of class II major histocompatibility complex gene subregions are differentially expressed on keratinocytes in cutaneous diseases.

D. Macdonald, J. Barker, J. Ophir, 1988, Journal of the American Academy of Dermatology.

An analysis of IL-36 signature genes and individuals with IL1RL2 knockout mutations validates IL-36 as a psoriasis therapeutic target

F. Ciccarelli, P. Di Meglio, M. Peakman, 2017, Science Translational Medicine.

Recommendations for the Long-Term Treatment of Psoriasis with Infliximab: A Dermatology Expert Group Consensus

J. Saurat, S. Chimenti, J. Ortonne, 2008, Dermatology.

Comparative Genetic Analysis of Psoriatic Arthritis and Psoriasis for the Discovery of Genetic Risk Factors and Risk Prediction Modeling

A. Barton, M. Brown, M. Simpson, 2022, Arthritis & rheumatology.

Modulation of keratinocyte-derived interleukin-8 which is chemotactic for neutrophils and T lymphocytes.

V. Dixit, S. Kunkel, J. Barker, 1991, The American journal of pathology.

Filaggrin null alleles are not associated with psoriasis.

R. McManus, C. Palmer, R. Trembath, 2007, The Journal of investigative dermatology.

Platelet activating factor-induced clinical and histopathologic responses in atopic skin and their modification by the platelet activating factor antagonist BN52063.

D. Macdonald, T. Lee, J. Barker, 1990, Journal of the American Academy of Dermatology.

Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity

Matti Pirinen, Christian Gieger, Peter Donnelly, 2012 .

Efficacy and safety of infliximab vs. methotrexate in patients with moderate‐to‐severe plaque psoriasis: results of an open‐label, active‐controlled, randomized trial (RESTORE1)

J. Ortonne, K. Reich, J. Barker, 2011, The British journal of dermatology.

Neuropeptides induce rapid expression of endothelial cell adhesion molecules and elicit granulocytic infiltration in human skin.

D. Macdonald, T. Lee, J. Barker, 1993, Journal of immunology.

Mediation of systemic vascular hyperpermeability in severe psoriasis by circulating vascular endothelial growth factor.

D. Creamer, J. Barker, M. Allen, 2002, Archives of dermatology.

Null mutations in the filaggrin gene (FLG) determine major susceptibility to early-onset atopic dermatitis that persists into adulthood.

C. Palmer, R. Trembath, N. Reynolds, 2007, The Journal of investigative dermatology.

Efficacy and safety of infliximab as continuous or intermittent therapy in patients with moderate‐to‐severe plaque psoriasis: results of a randomized, long‐term extension trial (RESTORE2)

K. Reich, J. Barker, G. Wozel, 2013, The British journal of dermatology.

Demyelination during tumour necrosis factor antagonist therapy for psoriasis: a case report and review of the literature

T. Andrews, J. Barker, S. Mahil, 2013, The Journal of dermatological treatment.

Quality of life and patient benefit following transition from methotrexate to ustekinumab in psoriasis

S. Chimenti, J. Lambert, T. Luger, 2017, Journal of the European Academy of Dermatology and Venereology : JEADV.

Immunohistochemical evaluation of psoriatic plaques following selective photothermolysis of the superficial capillaries

J. Barker, P. Mortimer, M. Allen, 2001, British Journal of Dermatology.

Association Between Tumor Necrosis Factor Inhibitors and the Risk of Hospitalization or Death Among Patients With Immune-Mediated Inflammatory Disease and COVID-19

L. Trupin, E. Soriano, M. Gianfrancesco, 2021, JAMA network open.

Adalimumab for psoriasis patients who are non‐responders to etanercept: open‐label prospective evaluation

J. Barker, C. Smith, R. Groves, 2009, Journal of the European Academy of Dermatology and Venereology : JEADV.

Association of TNFA gene polymorphism at position –308 with susceptibility to irritant contact dermatitis

S. Wakelin, O. Baadsgaard, J. Barker, 2000, Immunogenetics.

A case-control study investigating candidate genes in adult eczema.

W. Cookson, M. Moffatt, N. Reynolds, 2005 .

Generalized pustular psoriasis is a disease distinct from psoriasis vulgaris: evidence and expert opinion

A. Burden, J. Barker, J. Krueger, 2022, Expert review of clinical immunology.

Epidermis as a pro-inflammatory organ.

J. Barker, 2005 .

Vascular proliferation and angiogenic factors in psoriasis

J. Barker, J. Barker, J. Creamer, 1995, Clinical and experimental dermatology.

Epidermal dendritic cells in psoriasis possess a phenotype associated with antigen presentation: in situ expression of beta 2-integrins.

J. McGregor, D. Macdonald, J. Barker, 1992, Journal of the American Academy of Dermatology.

AP1S3 Mutations Cause Skin Autoinflammation by Disrupting Keratinocyte Autophagy and Up-Regulating IL-36 Production

P. Soler-Palacín, P. Di Meglio, R. Trembath, 2016, The Journal of investigative dermatology.

Pustular Forms of Psoriasis Related to Autoinflammation

F. Capon, J. Barker, S. Mahil, 2019, Textbook of Autoinflammation.

Humoral and cellular immunogenicity to a second dose of COVID-19 vaccine BNT162b2 in people receiving methotrexate or targeted immunosuppression: a longitudinal cohort study

M. Brown, M. Malim, A. Cope, 2021, The Lancet Rheumatology.

HUT 78 T cells bind to noncytokine-stimulated keratinocytes using a non-CD18-dependent adhesion pathway.

J. Barker, B. Nickoloff, L. Stoolman, 1992, The American journal of pathology.

Corneodesmosin Expression in Psoriasis Vulgaris Differs from Normal Skin and Other Inflammatory Skin Disorders

R. Vaughan, A. Hayday, A. Ishida-Yamamoto, 2001, Laboratory Investigation.

Calcium homeostasis remains unaffected after 12 weeks' therapy with calcitriol 3 µg/g ointment; no correlation with extent of psoriasis

C. Griffiths, J. Barker, R. Groves, 2003, The Journal of dermatological treatment.

DIFFERENCES IN CLINICAL FEATURES AND COMORBID BURDEN BETWEEN HLA-C*06:02 CARRIER GROUPS IN MORE THAN 9,000 PEOPLE WITH PSORIASIS.

C. Curtis, M. Simpson, P. Di Meglio, 2021, The Journal of investigative dermatology.

Prevalence of Advanced Liver Fibrosis in Patients With Severe Psoriasis.

C. Lewis, J. Barker, R. Miquel, 2019, JAMA dermatology.

Biomarkers of disease progression in people with psoriasis: a scoping review

M. Acencio, Kath Wright, P. Di Meglio, 2022, The British journal of dermatology.

Enhanced meta-analysis and replication studies identify five new psoriasis susceptibility loci

Vinod Chandran, Andres Metspalu, Proton Rahman, 2015, Nature Communications.

Switching from a fumaric acid ester mixture to dimethylfumarate monotherapy in psoriasis

K. Reich, P. C. van de Kerkhof, J. Barker, 2019, Journal of the European Academy of Dermatology and Venereology : JEADV.

Morphologic Switch From Psoriasiform to Eczematous Dermatitis After Anti-IL-17 Therapy: A Case Series.

A. Pink, J. Barker, Catherine H. Smith, 2019, JAMA dermatology.

Staphylococcal toxin‐induced T cell proliferation in atopic eczema correlates with increased use of superantigen‐reactive Vβ‐chains in cutaneous lymphocyte‐associated antigen (CLA)‐positive lymphocytes

R. Vaughan, J. Barker, M. Allen, 2000, Clinical and experimental immunology.

Persistence with biologic therapies for the treatment of moderate to severe psoriasis: a prospective observational study from the British Association of Dermatologists Biologic Interventions Register (BADBIR).

A. Burden, N. Reynolds, M. Lunt, 2014 .

Susceptibility to Effects of UVB Irradiation on Induction of Contact Sensitivity, Relevance of Number and Function of Langerhans Cells and Epidermal Macrophages

L. Skov, J. Simon, O. Baadsgaard, 1998, Photochemistry and photobiology.

Contrasting effects of ultraviolet-A and ultraviolet-B exposure on induction of contact sensitivity in human skin.

L. Skov, J. Simon, O. Baadsgaard, 1997, Clinical and experimental immunology.

Cellular localization of interleukin-8 and its inducer, tumor necrosis factor-alpha in psoriasis.

James T. Elder, V. Dixit, S. Kunkel, 1991, The American journal of pathology.

Gamma‐interferon induced human keratinocyte HLA‐DR synthesis: the role of dermal activated T lymphocytes

D. Macdonald, I. Leigh, I. Leigh, 1988, The British journal of dermatology.

Combined analysis of genome-wide association studies for Crohn disease and psoriasis identifies seven shared susceptibility loci.

Christian Gieger, Andres Metspalu, Christopher G Mathew, 2012, American journal of human genetics.

Cutaneous lymphocyte trafficking in the inflammatory dermatoses

D. Macdonald, J. Barker, J. Barker, 1992, The British journal of dermatology.

Reply: Refinements in Upper Blepharoplasty: The Five-Step Technique

F. Capon, J. Barker, A. Navarini, 2019 .

Adhesion molecules in cutaneous inflammation.

J. Barker, J. Barker, 1995, Ciba Foundation symposium.

Keratinocyte HLA‐DR expression: the relationship to dermal lymphocytic infiltration

D. Macdonald, J. Barker, J. Ophir, 1987, Clinical and experimental dermatology.

Psoriasis: consensus on topical therapies

A. Menter, K. Kragballe, P. V. D. van de Kerkhof, 2008, Journal of the European Academy of Dermatology and Venereology : JEADV.

Surface-bound immunoglobulin E on antigen-presenting cells in cutaneous tissue of atopic dermatitis.

D. Macdonald, J. Barker, V. Alegre, 1988, The Journal of investigative dermatology.

PSENEN and NCSTN mutations in familial hidradenitis suppurativa (Acne Inversa).

M. Simpson, R. Trembath, A. Pink, 2011, The Journal of investigative dermatology.

Single-cell analysis implicates Th17 to Th2 cell plasticity in the pathogenesis of palmoplantar pustulosis.

A. Burden, N. Reynolds, F. Capon, 2022, The Journal of allergy and clinical immunology.

Damaging alleles affecting multiple CARD14 domains are associated with palmoplantar pustulosis.

Carmen Bugarin Diz, A. Burden, N. Reynolds, 2022, The Journal of investigative dermatology.

Excess melanocytic nevi in children with renal allografts.

J. McGregor, D. Macdonald, J. Barker, 1993, Journal of the American Academy of Dermatology.

Eruptive dysplastic naevi following renal transplantation

D. Macdonald, J. Barker, J. Barker, 1988, Clinical and experimental dermatology.

Does topical tacrolimus induce lentigines in children with atopic dermatitis? A report of three cases

J. Barker, C. Smith, A. Robson, 2005, The British journal of dermatology.

Keratinocyte expression of CD36 antigen in benign and malignant epidermal cell‐derived tumours

D. Macdonald, D. Macdonald, J. Barker, 1991, Journal of cutaneous pathology.

Role of keratinocytes in allergic contact dermatitis

J. Barker, J. Barker, 1992, Contact dermatitis.

Epidermal class II human lymphocyte antigen expression in atopic dermatitis: a comparison with experimental allergic contact dermatitis.

D. Macdonald, J. Barker, 1987, Journal of the American Academy of Dermatology.

Detection of interferon-gamma mRNA in psoriatic epidermis by polymerase chain reaction.

V. Dixit, J. Barker, V. Sarma, 1991, Journal of dermatological science.

Genetic aspects of psoriasis

J. Barker, 2001, Clinical and experimental dermatology.

Negligible impact of rare autoimmune-locus coding-region variants on missing heritability

D. MacArthur, J. Todd, J. Barrett, 2013, Nature.

Prevalent and low-frequency null mutations in the filaggrin gene are associated with early-onset and persistent atopic eczema.

H. Cordell, R. Trembath, C. Relton, 2008, The Journal of investigative dermatology.

In vivo UVA-1 and UVB irradiation differentially perturbs the antigen-presenting function of human epidermal Langerhans cells.

L. Skov, J. Simon, O. Baadsgaard, 1998, The Journal of investigative dermatology.

Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci

Søren Brunak, Buhm Han, Andres Metspalu, 2016, Nature Genetics.

Enhanced NF-κB signaling in type-2 dendritic cells at baseline predicts non-response to adalimumab in psoriasis

M. Barnes, F. Nestle, P. Di Meglio, 2021, Nature communications.

Enhanced NF-κB signaling in type-2 dendritic cells at baseline predicts non-response to adalimumab in psoriasis

R. Emsley, M. Barnes, K. Payne, 2020, Nature Communications.

European Society for Dermatological Research (ESDR): Shifting Scope and Expanding Boundaries, Promoting Cutaneous Biology Research across Europe and beyond.

C. Griffiths, M. Gilliet, J. Barker, 2017, The Journal of investigative dermatology.

Hamartoma moniliformis — a case report

D. Macdonald, J. Barker, 1988, Clinical and experimental dermatology.

A case of chromoblastomycosis responding to treatment with itraconazole

R. Hay, J. Barker, C. Smith, 1993, The British journal of dermatology.

Detection of circulating adhesion molecules in erythrodermic skin disease.

R W Groves, P. Kapahi, D. Macdonald, 1995, Journal of the American Academy of Dermatology.

Retinoid pharmacogenetics and vasular endothelial growth factor in chronic plaque psoriasis.

M. Detmar, C. Griffiths, J. Barker, 2005 .

A randomized, investigator‐masked clinical evaluation of the efficacy and safety of clobetasol propionate 0.05% shampoo and tar blend 1% shampoo in the treatment of moderate to severe scalp psoriasis

A. Finlay, C. Griffiths, J. Barker, 2006, The Journal of dermatological treatment.

The pathophysiology of psoriasis

J. Barker, 1991, The Lancet.

Recommendations for the use of etanercept in psoriasis: a European dermatology expert group consensus

J. Saurat, S. Chimenti, A. Giannetti, 2006, Journal of the European Academy of Dermatology and Venereology : JEADV.

Mechanisms of Disease: Psoriasis.

Frank O. Nestle, F. Nestle, J. Barker, 2009 .

Psoriasis and systemic inflammatory diseases: potential mechanistic links between skin disease and co-morbid conditions.

Luis Puig, Giampiero Girolomoni, Paul Emery, 2010, The Journal of investigative dermatology.

Psoriasis: a brief overview.

J. Barker, S. Mahil, A. Raharja, 2021, Clinical medicine.

Pathogenesis and clinical features of psoriasis

C. Griffiths, J. Barker, Christopher EM Griffiths, 2007, The Lancet.

Physician perspectives in the management of psoriasis and psoriatic arthritis: results from the population‐based Multinational Assessment of Psoriasis and Psoriatic Arthritis survey

M. Lebwohl, G. Girolomoni, A. Kavanaugh, 2015, Journal of the European Academy of Dermatology and Venereology : JEADV.

Microbial and transcriptional differences elucidate atopic dermatitis heterogeneity across skin sites

J. Kere, D. Greco, S. Tsoka, 2020, Allergy.

Psoriasis in practice

A. Menter, J. Barker, J. Barker, 1991, The Lancet.

(60) Basal cell naevus syndrome (lacking basal cell carcinomata)

D. Macdonald, J. Barker, 1988 .

Patient perspectives in the management of psoriasis: results from the population-based Multinational Assessment of Psoriasis and Psoriatic Arthritis Survey.

M. Lebwohl, G. Girolomoni, A. Kavanaugh, 2014, Journal of the American Academy of Dermatology.

Clinical use of dimethyl fumarate in moderate‐to‐severe plaque‐type psoriasis: a European expert consensus

L. Naldi, L. Iversen, K. Reich, 2018, Journal of the European Academy of Dermatology and Venereology : JEADV.

Alterations induced in normal human skin by in vivo interferon‐gamma

D. Macdonald, J. Barker, M. Allen, 1990, The British journal of dermatology.

Characterization of the major susceptibility region for psoriasis at chromosome 6p21.3.

A. Little, R. Trembath, J. Barker, 1999, The Journal of investigative dermatology.

What does acne genetics teach us about disease pathogenesis?

J. Common, J. Barker, M. V. van Steensel, 2019, The British journal of dermatology.

Methotrexate and liver fibrosis in people with psoriasis: a systematic review of observational studies

A. Dhillon, J. Barker, Z. Jabbar-Lopez, 2014, The British journal of dermatology.

British Association of Dermatologists guidelines for use of biological interventions in psoriasis 2005

A. Finlay, A. Burden, N. Reynolds, 2005, The British journal of dermatology.

Screening for anxiety and depression in people with psoriasis: a cross‐sectional study in a tertiary referral setting

Charles H. Smith, M. Hotopf, F. Matcham, 2017, The British journal of dermatology.

Cross-disorder analysis of schizophrenia and 19 immune-mediated diseases identifies shared genetic risk

Stephanie A. Santorico, H. Hakonarson, S. Raychaudhuri, 2019, Human molecular genetics.

Genetic correlations among psychiatric and immune‐related phenotypes based on genome‐wide association data

James T. Elder, H. Hakonarson, S. Grant, 2018, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

Integrative Biology Approach Identifies Cytokine Targeting Strategies for Psoriasis

S. Tsoka, W. Ouyang, M. Mirza, 2014, Science Translational Medicine.

Mutations in IL36RN/IL1F5 are associated with the severe episodic inflammatory skin disease known as generalized pustular psoriasis.

M. Simpson, S. Spain, F. Nestle, 2011, American journal of human genetics.

Haplotype analysis of distantly related populations implicates corneodesmosin in psoriasis susceptibility

R. Trembath, D. Tillman, F. Capon, 2003, Journal of medical genetics.

Family-based analysis using a dense single-nucleotide polymorphism-based map defines genetic variation at PSORS1, the major psoriasis-susceptibility locus.

R. Trembath, D. Tillman, F. Capon, 2002, American journal of human genetics.

Coding haplotype analysis supports HCR as the putative susceptibility gene for psoriasis at the MHC PSORS1 locus.

X. Estivill, J. Kere, S. Ripatti, 2002, Human molecular genetics.

Identification of a major susceptibility locus on chromosome 6p and evidence for further disease loci revealed by a two stage genome-wide search in psoriasis.

J. Browne, J. Terwilliger, G. Lathrop, 1997, Human molecular genetics.

Allele-specific cytokine responses at the HLA-C locus, implications for psoriasis

S. Chimenti, A. Hayday, F. Nestle, 2011, The Journal of investigative dermatology.

An update on the genetics of psoriasis.

R. Trembath, F. Capon, J. Barker, 2004, Dermatologic clinics.

Conditional analysis identifies three novel major histocompatibility complex loci associated with psoriasis.

M. Weale, A. Hayday, S. Spain, 2012, Human molecular genetics.

Cross-disorder analysis of schizophrenia and 19 immune diseases reveals genetic correlation

Stephanie A. Santorico, S. Raychaudhuri, M. Mayes, 2018, bioRxiv.

Running Head: Genetic Correlations: Brain & Immune Phenotypes-1 1 Title: Genetic correlations among neuro-behavioral and immune-related phenotypes based on genome-

Annegret, James T. Elder, H. Hakonarson, 2017 .

Polygenic analysis of schizophrenia and 19 immune diseases reveals modest pleiotropy Running Title : Pleiotropy between schizophrenia and autoimmunity

Stephanie A. Santorico, S. Raychaudhuri, M. Mayes, 2016 .

Activating CARD14 Mutations Are Associated with Generalized Pustular Psoriasis but Rarely Account for Familial Recurrence in Psoriasis Vulgaris.

J. McGrath, R. Trembath, F. Capon, 2015, The Journal of investigative dermatology.

IL36RN mutations define a severe autoinflammatory phenotype of generalized pustular psoriasis.

C. Prins, P. Soler-Palacín, R. Trembath, 2015, The Journal of allergy and clinical immunology.

Genome-wide Comparative Analysis of Atopic Dermatitis and Psoriasis Gives Insight into Opposing Genetic Mechanisms

James T. Elder, C. Gieger, M. Nöthen, 2015, American journal of human genetics.

Psoriasis heritability: 125 years and counting

J. Barker, 2014, The British journal of dermatology.

Psoriasis and other complex trait dermatoses: from loci to functional pathways

R. Trembath, A. Burden, F. Capon, 2011, The Journal of investigative dermatology.

Meta-analysis confirms the LCE3C_LCE3B deletion as a risk factor for psoriasis in several ethnic groups and finds interaction with HLA-Cw6.

Rafael de Cid, Pui-Yan Kwok, Xavier Estivill, 2011, The Journal of investigative dermatology.

Differential contribution of CDKAL1 variants to psoriasis, Crohn's disease and type II diabetes

Jane Worthington, R. Trembath, A. Burden, 2009, Genes and Immunity.

The immunopathology of psoriasis.

J. Barker, 1994, Bailliere's clinical rheumatology.

Genome-wide meta-analysis implicates mediators of hair follicle development and morphogenesis in risk for severe acne

T. Spector, Sue Hood, C. Curtis, 2018, Nature Communications.

Differential Drug Survival of Biologic Therapies for the Treatment of Psoriasis: A Prospective Observational Cohort Study from the British Association of Dermatologists Biologic Interventions Register (BADBIR).

A. Burden, N. Reynolds, M. Lunt, 2015, The Journal of investigative dermatology.

Re-Categorization of Psoriasis Severity: Delphi Consensus from the International Psoriasis Council.

B. Strober, A. Kimball, J. M. van der Walt, 2019, Journal of the American Academy of Dermatology.

Clinical and genetic differences between pustular psoriasis subtypes

Kaspar Torz, A. Burden, N. Reynolds, 2018, The Journal of allergy and clinical immunology.

AP1S3 mutations are associated with pustular psoriasis and impaired Toll-like receptor 3 trafficking.

A. Smahi, C. Prins, M. Simpson, 2014, American journal of human genetics.

Rare pathogenic variants in IL36RN underlie a spectrum of psoriasis-associated pustular phenotypes.

M. Simpson, R. Trembath, A. Burden, 2013, The Journal of investigative dermatology.

Loss-of-Function Myeloperoxidase Mutations Are Associated with Increased Neutrophil Counts and Pustular Skin Disease

M. Mockenhaupt, A. Burden, N. Reynolds, 2020, American journal of human genetics.

Rare variations in IL36RN in severe adverse drug reactions manifesting as acute generalized exanthematous pustulosis.

M. Simpson, R. Trembath, M. Mockenhaupt, 2013, The Journal of investigative dermatology.

Identification of rare, disease-associated variants in the promoter region of the RNF114 psoriasis susceptibility gene.

M. Simpson, R. Trembath, A. Burden, 2012, The Journal of investigative dermatology.

Identification of ZNF313/RNF114 as a novel psoriasis susceptibility gene.

Richard C Trembath, Alexander Gutin, Victor Abkevich, 2008, Human molecular genetics.

Expression of E‐cadherin in human epidermal non‐melanoma cutaneous tumours

D. Macdonald, J. Barker, M. Montesu, 1996, The British journal of dermatology.

Monocyte chemotaxis and activating factor production by keratinocytes in response to IFN-gamma.

V. Dixit, P. Ward, J. Barker, 1991, Journal of immunology.

European S3‐Guidelines on the systemic treatment of psoriasis vulgaris – Update 2015 – Short version – EDF in cooperation with EADV and IPC

P. Gisondi, K. Papp, K. Reich, 2015, Journal of the European Academy of Dermatology and Venereology : JEADV.

Skin immune system (SIS): cutaneous immunology and clinical immunodermatology.

J. Barker, 2005 .

The effect of methotrexate and targeted immunosuppression on humoral and cellular immune responses to the COVID-19 vaccine BNT162b2: a cohort study

M. Brown, M. Malim, A. Cope, 2021, The Lancet Rheumatology.

HLA-C*06:02 genotype is a predictive biomarker of biologic treatment response in psoriasis.

C. Curtis, M. Simpson, S. Lee, 2019, The Journal of allergy and clinical immunology.

Genetics of psoriasis: the potential impact on new therapies.

A. Bowcock, J. Barker, 2003, Journal of the American Academy of Dermatology.

Altered vascular endothelium integrin expression in psoriasis.

D. Creamer, J. Barker, M. Allen, 1995, The American journal of pathology.

Microbe-host interplay in atopic dermatitis and psoriasis

J. Kere, D. Greco, S. Katayama, 2019, Nature Communications.

IL-36 Promotes Systemic IFN-I Responses in Severe Forms of Psoriasis

F. Ciccarelli, A. Burden, F. Capon, 2020, The Journal of investigative dermatology.

Interleukin-36 promotes systemic Type-I IFN responses in severe psoriasis

F. Ciccarelli, A. Burden, F. Capon, 2018, bioRxiv.

Using Real‐World Data to Guide Ustekinumab Dosing Strategies for Psoriasis: A Prospective Pharmacokinetic‐Pharmacodynamic Study

R. Emsley, M. Barnes, K. Payne, 2020, Clinical and translational science.

Association of Serum Ustekinumab Levels With Clinical Response in Psoriasis

D. Stocken, A. Burden, N. Reynolds, 2019, JAMA dermatology.

Defining the Therapeutic Range for Adalimumab and Predicting Response in Psoriasis: A Multicenter Prospective Observational Cohort Study

D. Stocken, A. Burden, N. Reynolds, 2019, The Journal of investigative dermatology.

The role of IL‐23 and the IL‐23/TH17 immune axis in the pathogenesis and treatment of psoriasis

G. Girolomoni, J. Barker, W. Boehncke, 2017, Journal of the European Academy of Dermatology and Venereology : JEADV.

Absence of association between asthma and high serum immunoglobulin E associated GPRA haplotypes and adult atopic dermatitis.

C. Lindgren, J. Kere, R. Trembath, 2005, The Journal of investigative dermatology.

Leukocyte-endothelium interactions in cutaneous inflammatory processes

J. Barker, B. Nickoloff, 2004, Springer Seminars in Immunopathology.

ESDR 2010-2020: Journey toward Translational and Systems Dermatology.

T. Biedermann, M. Picardo, J. Barker, 2020, The Journal of investigative dermatology.

A standardization approach to compare treatment safety and effectiveness outcomes between clinical trials and real‐world populations in psoriasis

A. Burden, C. Griffiths, M. Lunt, 2019, The British journal of dermatology.

A European subset analysis from the population‐based Multinational Assessment of Psoriasis and Psoriatic Arthritis shows country‐specific features: results from psoriasis patients in Spain

G. Girolomoni, K. Reich, P. V. D. van de Kerkhof, 2017, Journal of the European Academy of Dermatology and Venereology : JEADV.

Factors associated with adverse COVID-19 outcomes in patients with psoriasis—insights from a global registry–based study

S. Feldman, L. Naldi, E. Freeman, 2020, Journal of Allergy and Clinical Immunology.

G. Girolomoni, J. Barker, A. Egeberg, 2019, The Journal of dermatological treatment.

Langerhans' cell expression of the selectin ligand, sialyl Lewis x.

D. Macdonald, J. Barker, A. Chu, 1994, Immunology.

Interaction between genetic control of vascular endothelial growth factor production and retinoid responsiveness in psoriasis.

M. Detmar, H. Young, C. Griffiths, 2006, The Journal of investigative dermatology.

Expression of selectin ligands by cutaneous squamous cell carcinoma.

D. Macdonald, J. Barker, M. Allen, 1993, The American journal of pathology.

E-selectin binds to squamous cell carcinoma and keratinocyte cell lines.

D. Macdonald, J. Barker, P. Stephens, 1996, The Journal of investigative dermatology.

Association of Patient Mental Health Status With the Level of Agreement Between Patient and Physician Ratings of Psoriasis Severity.

A. Pink, K. Goldsmith, E. Carr, 2021, JAMA dermatology.

Induction of thrombospondin-1 partially mediates the anti-angiogenic activity of dexrazoxane

Z. Nagy, J. Barker, R. Bicknell, 2009, British Journal of Cancer.

Risk of major cardiovascular events in patients with psoriasis receiving biologic therapies: a prospective cohort study

M. Rutter, A. Burden, N. Reynolds, 2019, Journal of the European Academy of Dermatology and Venereology : JEADV.

Genome-wide association meta-analysis identifies 29 new acne susceptibility loci

Laurent F. Thomas, Michelle K. Lupton, Jiali Han, 2022, Nature Communications.

Searching for the major histocompatibility complex psoriasis susceptibility gene.

R. Trembath, F. Capon, J. Barker, 2002, The Journal of investigative dermatology.

A case of metastatic malignant melanoma masquerading as disseminated mammary carcinoma

J. Barker, A. Girling, 1989, Histopathology.

Genetic association analysis using data from triads and unrelated subjects.

Chun Li, Michael P Epstein, Richard C Trembath, 2005, American journal of human genetics.

Adhesion molecules in allergic inflammation.

T. Lee, J. Barker, C. Smith, 1993, The American review of respiratory disease.

The Psoriasis Risk Allele HLA-C*06:02 Shows Evidence of Association with Chronic or Recurrent Streptococcal Tonsillitis

J. Kere, P. Jousilahti, P. Saavalainen, 2018, Infection and Immunity.

endothelial hypoxic stress protein Identification of protein disulfide isomerase as an

A. Harris, Tsonwin Hai, R. Poulsom, 2005 .

An In-Depth Characterization of the Major Psoriasis Susceptibility Locus Identifies Candidate Susceptibility Alleles within an HLA-C Enhancer Element

M. Simpson, A. Hayday, S. Spain, 2013, PloS one.

Methotrexate polyglutamates as a marker of patient compliance and clinical response in psoriasis: a single‐centre prospective study

C. Lewis, S. West, J. Barker, 2012, The British journal of dermatology.

Intentional and Unintentional Medication Non-Adherence in Psoriasis: The Role of Patients’ Medication Beliefs and Habit Strength

R. Emsley, K. Payne, D. Stocken, 2017, The Journal of investigative dermatology.

Meeting Report: Psoriasis Stratification to Optimise Relevant Therapy Showcase.

R. Emsley, M. Barnes, P. Di Meglio, 2021, The Journal of investigative dermatology.

The clinical genetics of Psoriasis.

J. Barker, E. Campalani, 2005 .

Cell trafficking and role of adhesion molecules in psoriasis.

J. Barker, C. Smith, Catherine Smith, 1995, Clinics in dermatology.

Functional analysis of the RNF114 psoriasis susceptibility gene implicates innate immune responses to double-stranded RNA in disease pathogenesis.

Richard C Trembath, R. Trembath, F. Capon, 2011, Human molecular genetics.

(28) Dermatology at Guy's Hospital: the first hundred years

D. Macdonald, J. Barker, R. Wells, 1988 .

Comparative effects of biological therapies on the severity of skin symptoms and health-related quality of life in patients with plaque-type psoriasis: a meta-analysis.

K. Reich, C. Griffiths, J. Barker, 2008, Current medical research and opinion.

The interleukin 1 receptor antagonist anakinra to reduce disease severity of palmoplantar pustulosis in adults: APRICOT RCT and PLUM mechanistic study

F. Capon, C. Griffiths, A. Pink, 2022, Efficacy and Mechanism Evaluation.

Loss of IL36RN function does not confer susceptibility to psoriasis vulgaris.

R. Trembath, A. Burden, F. Capon, 2014, The Journal of investigative dermatology.

Genetic analysis of PSORS1 distinguishes guttate psoriasis and palmoplantar pustulosis.

J. Kere, R. Trembath, C. Griffiths, 2003, The Journal of investigative dermatology.

Loss-of-function myeloperoxidase mutations are associated with increased neutrophil counts and pustular skin disease

M. Mockenhaupt, A. Burden, N. Reynolds, 2021, American journal of human genetics.

European consensus statement on phenotypes of pustular psoriasis: ESDR 2016 Annual Meeting Abstract SupplementEuropean Society for Dermatological Research (ESDR) Annual Meeting

F. Capon, J. Barker, U. Mrowietz, 2016 .

Global reporting of cases of COVID‐19 in psoriasis and atopic dermatitis: an opportunity to inform care during a pandemic

C. Flohr, P. Di Meglio, N. Dand, 2020, The British journal of dermatology.

Optimising the Use of Tazarotene in Clinical Practice: Consensus Statement from the European Advisory Panel for Tazarotene (Zorac™)

J. Saurat, H. Gollnick, J. Revuz, 1999, Dermatology.

Comparative effects of biological therapies on the severity of skin symptoms and health-related quality of life in patients with plaque-type psoriasis: a meta-analysis

K. Reich, C. Griffiths, J. Barker, 2008 .

(57) Actinic granuloma annulare

D. Macdonald, J. Barker, R. Groves, 1991 .

Comprar Rook's Textbook Of Dermatology, 4 Vols. 9ª Ed. | C. Griffiths | 9781118441190 | Wiley

D. Creamer, C. Griffiths, J. Barker, 2016 .

A non-HLA gene within the MHC in psoriasis

R. Vaughan, R. Trembath, J. Barker, 1999, The Lancet.

Characteristics and skin cancer risk of psoriasis patients with a history of skin cancer in BADBIR

A. Burden, N. Reynolds, A. Green, 2021, Journal of the European Academy of Dermatology and Venereology : JEADV.

Application of information theoretic feature selection and machine learning methods for the development of genetic risk prediction models

A. Barton, M. Simpson, J. Bowes, 2021, Scientific Reports.

Biomarkers of systemic treatment response in people with psoriasis: a scoping review

M. Acencio, Kath Wright, P. Di Meglio, 2022, The British journal of dermatology.

Genetic analysis of PSORS2 markers in a UK dataset supports the association between RAPTOR SNPs and familial psoriasis

A. Bowcock, R. Trembath, C. Helms, 2004, Journal of Medical Genetics.

Identification of a novel psoriasis susceptibility locus at 1p and evidence of epistasis between PSORS1 and candidate loci

R. Trembath, D. Tillman, A. Burden, 2001, Journal of medical genetics.

Psoriasis

J. Barker, 1997, Journal of the Royal College of Physicians of London.

Staging of fibrosis Indirect Biomarkers Direct Biomarkers Combinational panels Proteomics profiles Liver Biopsy Liver imaging

A. Douiri, J. Barker, C. Smith, 2014 .

The value of monitoring ciclosporin concentration 2 hours post-dose (C2) in dermatology: A prospective cohort study

J. Barker, S. Bashir, A. Chew, 2011, The Journal of dermatological treatment.

Pulmonary capillary leak syndrome complicating generalized pustular psoriasis: possible role of cytokines

J. McGregor, D. Macdonald, J. Barker, 1991, The British journal of dermatology.

The IL23R A/Gln381 Allele Promotes IL-23 Unresponsiveness in Human Memory T-Helper 17 Cells and Impairs Th17 Responses in Psoriasis Patients

J. Todd, S. Nutland, F. Villanova, 2013, The Journal of investigative dermatology.

Psoriasis is associated with pleiotropic susceptibility loci identified in type II diabetes and Crohn disease

N. Prescott, C. Mathew, R. Trembath, 2007, Journal of Medical Genetics.

A Strategic Approach to Setting the Research Agenda in Psoriasis

A. Kimball, W. Sterry, J. Barker, 2011 .

Improving clinical trial design in psoriasis: Perspectives from the global dermatology community

E. Horn, A. Menter, W. Sterry, 2011, Journal of dermatological treatment (Print).

The major psoriasis susceptibility locus PSORS1 is not a risk factor for late-onset psoriasis.

Richard C Trembath, R. Trembath, A. Burden, 2005, The Journal of investigative dermatology.

Polymorphisms in IL-1B distinguish between psoriasis of early and late onset.

A. Barton, J. Bowes, H. Hébert, 2014, The Journal of investigative dermatology.

An association between psoriasis and hereditary multiple exostoses. A clue for the mapping of a psoriasis susceptibility gene?

R. Trembath, J. Barker, J. Leigh, 1994, The British journal of dermatology.

Cross-disorder analysis of schizophrenia and 19 immune diseases reveals genetic correlation

Stephanie A. Santorico, S. Raychaudhuri, M. Mayes, 2016, bioRxiv.

Psoriasis as a T cell-mediated autoimmune disease.

J. Barker, 1998, Hospital medicine.

Genome-wide meta-analysis implicates mediators of hair follicle development and morphogenesis in risk for severe acne

T. Spector, Sue Hood, C. Curtis, 2018, Nature Communications.

Diagnosing liver fibrosis: a narrative review of current literature for dermatologists

J. Barker, K. Agarwal, A. Salam, 2017, The British journal of dermatology.

Long‐wave UVA offers partial protection against UVB‐induced immune suppression in human skin

L. Skov, J. Simon, BJARNE K. Ersbøll, 2000, APMIS : acta pathologica, microbiologica, et immunologica Scandinavica.

Exclusion of interleukin-1 receptor antagonist as a primary disease determinant for psoriasis.

R. Trembath, J. Barker, J. Rosbotham, 1995, The Journal of investigative dermatology.

The genes that cause psoriasis

J. Barker, 2000, Clinical and experimental dermatology.

Interleukin-36 promotes systemic Type-I IFN responses in severe forms of psoriasis

F. Ciccarelli, F. Capon, H. Young, 2019 .

DIFFERENCES IN CLINICAL FEATURES AND COMORBID BURDEN BETWEEN HLA-C*06:02 CARRIER GROUPS IN MORE THAN 9,000 PEOPLE WITH PSORIASIS.

C. Curtis, M. Simpson, P. Di Meglio, 2021, The Journal of investigative dermatology.

The early dermatologists of Guy's Hospital.

D. Macdonald, J. Barker, R. Wells, 1990, Journal of the American Academy of Dermatology.

Conditional analysis identifies three novel major histocompatibility complex loci associated with psoriasis.

M. Weale, A. Hayday, S. Spain, 2012, Human molecular genetics.

Identification of rare, disease-associated variants in the promoter region of the RNF114 psoriasis susceptibility gene.

M. Simpson, R. Trembath, A. Burden, 2012, The Journal of investigative dermatology.

Intentional and Unintentional Medication Non-Adherence in Psoriasis: The Role of Patients’ Medication Beliefs and Habit Strength

K. Payne, D. Stocken, L. Cordingley, 2017, The Journal of investigative dermatology.

Genetic correlations among psychiatric and immune-related Genetic correlations among psychiatric and immune-related phenotypes based on genome-wide association data [preprint] phenotypes based on genome-wide association data [preprint]

James T. Elder, H. Hakonarson, S. Grant, 2020 .

Generalized pustular eruptions: time to adapt the disease taxonomy to the genetic architecture?

M. Simpson, R. Trembath, M. Mockenhaupt, 2014, The Journal of investigative dermatology.

Ultraviolet B induced suppression of induction of contact sensitivity in human skin is not associated with tumour necrosis factor-alpha-308 or interleukin-10 genetic polymorphisms.

R Trembath, M H Allen, L Skov, 1998, The British journal of dermatology.