C. Marcus

发表

Alternative Splicing in the Cytochrome P450 Superfamily Expands Protein Diversity to Augment Gene Function and Redirect Human Drug Metabolism

P. Iversen, A. Annalora, C. Marcus, 2017, Drug Metabolism and Disposition.

Immobilized Artificial Membrane Chromatography: Surface Chemistry and Applications

C. Marcus, C. Pidgeon, F. M. Alvarez, 1991 .

Tobacco smoke induces CYP1B1 in the aerodigestive tract.

N. Altorki, L. Kopelovich, J. Port, 2004, Carcinogenesis.

Evidence for an Aryl Hydrocarbon Receptor-Mediated Cytochrome P450 Autoregulatory Pathway

G. Perdew, C. Marcus, C. Chiaro, 2007, Molecular Pharmacology.

Evidence for an Ah receptor-mediated cytochrome P 450 auto-regulatory pathway

G. Perdew, C. Marcus, C. Chiaro, 2007 .

2,3,7,8-tetrachlorodibenzo-p-dioxin induces CYP1B1 expression in human luteinized granulosa cells.

C. Vandevoort, C. Marcus, A. Conley, 2005, Archives of biochemistry and biophysics.

Expression of cytochrome P450 CYP1B1 in breast cancer

W. F. Greenlee, J. McKay, G. Murray, 1995, FEBS letters.

Hybrid homology modeling and mutational analysis of cytochrome P450C24A1 (CYP24A1) of the Vitamin D pathway: insights into substrate specificity and membrane bound structure-function.

R. Serda, A. Annalora, C. Marcus, 2007, Archives of biochemistry and biophysics.

Inhibition of benzo[a]pyrene metabolism by insulin, FITC-insulin and an FITC-insulin-antibody conjugate in the human hepatoma cell line HepG2.

R. Polzer, W. Baird, C. Marcus, 1995, Chemico-biological interactions.

Rat cytochrome P450C24 (CYP24A1) and the role of F249 in substrate binding and catalytic activity.

M. Chiu, E. Bobrovnikova-Marjon, R. Serda, 2004, Archives of biochemistry and biophysics.

Effects of synthetic and naturally occurring flavonoids on benzo[a]pyrene metabolism by hepatic microsomes prepared from rats treated with cytochrome P-450 inducers.

W. Baird, C. Marcus, Y. Chae, 1991, Cancer letters.

Selective induction of cytochrome P450 isozymes in rat liver by 4-n-alkyl-methylenedioxybenzenes.

C. Jefcoate, C. Marcus, C. F. Wilkinson, 1990, Archives of biochemistry and biophysics.

Methylenedioxyphenyl compounds as inducers of cytochrome P-450 and monooxygenase activity in the southern armyworm (Spodoptera eridania) and the rat

C. Marcus, C. F. Wilkinson, M. Murray, 1986 .

Spectral and inhibitory interactions of methylenedioxyphenyl and related compounds with purified isozymes of cytochrome P-450.

C. Marcus, C. F. Wilkinson, M. Murray, 1985, Xenobiotica; the fate of foreign compounds in biological systems.

Induction of superoxide by 12‐O‐tetradecanoylphorbol‐13‐acetate and thapsigargin, a non‐phorbol‐ester—type tumor promoter, in peritoneal macrophages elicited from SENCAR and B6C3F1 mice: A permissive role for the arachidonic acid cascade in signal transduction

C. Marcus, R. Pfeifer, H. L. Yoon, 1993, Molecular carcinogenesis.

Effects of synthetic and naturally occurring flavonoids on metabolic activation of benzo[a]pyrene in hamster embryo cell cultures.

W. Baird, C. Marcus, Y. Chae, 1992, Chemico-biological interactions.

Modulation of aryl hydrocarbon receptor (AHR)-dependent signaling by peroxisome proliferator-activated receptor β/δ (PPARβ/δ) in keratinocytes.

S. Amin, J. Peters, F. Gonzalez, 2014, Carcinogenesis.

thrombospondin-2 expression endothelium through decreased intracellular oxidative stress and CYP1B1 expression promotes the proangiogenic phenotype of

C. Sorenson, N. Sheibani, C. Jefcoate, 2013 .

CYP1B1 expression promotes the proangiogenic phenotype of endothelium through decreased intracellular oxidative stress and thrombospondin-2 expression.

C. Sorenson, N. Sheibani, C. Jefcoate, 2009, Blood.

The time-dependent increase in the binding of benzo[a]pyrene to DNA through (+)-anti-benzo[a]pyrene-7,8-diol-9,10-epoxide in primary rat hepatocyte cultures results from induction of cytochrome P450IA1 by benzo[a]pyrene treatment.

W. Baird, C. Marcus, H. Gelboin, 1992, Carcinogenesis.

Selective interactions of cytochromes P-450 with the hydroxymethyl derivatives of 7,12-dimethylbenz[a]anthracene.

C. Jefcoate, C. Marcus, M. Christou, 1986, Carcinogenesis.

Immunolocalization of CYP1B1 in normal, human, fetal and adult eyes.

B. Bejjani, C. Marcus, D. Edward, 2006, Experimental eye research.

Minireview Alternative Splicing in the Cytochrome P450 Superfamily Expands Protein Diversity to Augment Gene Function and Redirect Human Drug Metabolism s

P. Iversen, A. Annalora, C. Marcus, 2017 .

Stimulation of mouse Cyp1b1 during adipogenesis: characterization of promoter activation by the transcription factor Pax6.

C. Jefcoate, C. Marcus, Tie-gang Tong, 2013, Archives of biochemistry and biophysics.

Cytochrome P450 1B1: A Key Regulator of Ocular Iron Homeostasis and Oxidative Stress

C. Sorenson, N. Sheibani, C. Jefcoate, 2022, Cells.

Selective expression of cytochrome P450 isozymes by 4-n-alkyl-methylenedioxybenzenes in rat lung cells.

C. Jefcoate, C. Marcus, I. Keith, 1990, Archives of biochemistry and biophysics.

Selectivity in the binding of hydroxylated benzo[a]pyrene derivatives to purified cytochrome P-450c.

C. Jefcoate, C. Marcus, C. Turner, 1985, Biochemistry.

Quantitative Structure‐Activity Relationships in the Displacement of the Dihydrosafrole Metabolite‐Cytochrome P‐450 Complex

C. Marcus, C. F. Wilkinson, M. Murray, 1985 .

Biologically active components of anise: toxicity and interactions with insecticides in insects

C. Marcus, E. Lichtenstein, 1979 .

Interactions of naturally occurring food plant components with insecticides and pentobarbital in rats and mice.

C. Marcus, E. Lichtenstein, 1982, Journal of agricultural and food chemistry.

Heat Shock Protein 90 Inhibitors Suppress Aryl Hydrocarbon Receptor–Mediated Activation of CYP1A1 and CYP1B1 Transcription and DNA Adduct Formation

K. Subbaramaiah, A. Dannenberg, C. Marcus, 2008, Cancer Prevention Research.

Alternative Splicing in the Nuclear Receptor Superfamily Expands Gene Function to Refine Endo-Xenobiotic Metabolism

P. Iversen, A. Annalora, C. Marcus, 2020, Drug Metabolism and Disposition.

Alternative Splicing in the Nuclear Receptor Superfamily Expands Gene Function to Refine Endo-Xenobiotic Metabolism

P. Iversen, A. Annalora, C. Marcus, 2020, Drug Metabolism and Disposition.

Alternative splicing of the vitamin D receptor modulates target gene expression and promotes ligand‐independent functions

P. Iversen, A. Annalora, C. Marcus, 2019, Toxicology and applied pharmacology.

Antisense oligonucleotide development for the selective modulation of CYP3A5 in renal disease

P. Iversen, J. Himmelfarb, A. Annalora, 2021, Scientific Reports.

Role of the aryl hydrocarbon receptor in drug metabolism

G. Perdew, C. Marcus, P. Ramadoss, 2005, Expert opinion on drug metabolism & toxicology.

Effect of p-xylene inhalation on the bioactivation of bromobenzene in rat lung and liver.

C. Marcus, G. Carlson, B. Day, 1992, Fundamental and applied toxicology : official journal of the Society of Toxicology.

A k-mer based transcriptomics approach for antisense drug discovery targeting the Ewing’s family of tumors

P. Iversen, J. Summerton, A. Annalora, 2018, Oncotarget.

Cytochrome P450 purification and immunological detection in an insecticide resistant strain of German cockroach (Blattella germanica, L.).

C. Marcus, M. Scharf, G. Bennett, 1998, Insect biochemistry and molecular biology.

Expression of CYP1A1 and CYP1B1 in human endothelial cells: regulation by fluid shear stress.

L. McIntire, H. Jo, D. Weiss, 2009, Cardiovascular research.

Expression of CYP 1 A 1 and CYP 1 B 1 in human endothelial cells : regulation by fluid shear stress

L. McIntire, H. Jo, D. Weiss, 2009 .

In vitro exposure to environmental tobacco smoke induces CYP1B1 expression in human luteinized granulosa cells.

C. Vandevoort, C. Marcus, A. Conley, 2006, Reproductive toxicology.

Structure-activity relationships in the interactions of alkoxymethylenedioxybenzene derivatives with rat hepatic microsomal mixed-function oxidases in vivo.

C. Marcus, C. F. Wilkinson, M. Murray, 1983, Molecular pharmacology.

Complex chemical signals dictate Ah receptor activation through the gut-lung axis

D. Desai, Imhoi Koo, G. Perdew, 2023, bioRxiv.

Role of cytochrome P450 enzyme induction in the metabolic activation of benzo[c]phenanthrene in human cell lines and mouse epidermis.

D. Jerina, S. Amin, W. Baird, 1997, Chemical research in toxicology.

Contribution of circulating host and microbial tryptophan metabolites towards Ah receptor activation

P. Kris-Etherton, G. Perdew, A. Annalora, 2023, bioRxiv.

Molecular basis of dioxin actions on rodent and human target tissues.

C. Marcus, T. Sutter, W. Greenlee, 1994, Progress in clinical and biological research.

Roles of Cytochrome P450 1A1 and 1B1 in Metabolic Activation of Dibenzo[a, l]Pyrene by Microsomes from the Human Mammary Carcinoma Cell Line MCF-7

F. Guengerich, W. Baird, C. Marcus, 2000 .

Complex chemical signals dictate Ah receptor activation through the gut–lung axis

D. Desai, Imhoi Koo, G. Perdew, 2023, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Endogenous Tryptophan-Derived Ah Receptor Ligands are Dissociated from CYP1A1/1B1-Dependent Negative-Feedback

G. Perdew, A. Annalora, C. Marcus, 2023, International journal of tryptophan research : IJTR.

Immobilized artificial membrane chromatography: rapid purification of functional membrane proteins.

C. Jefcoate, C. Marcus, C. Pidgeon, 1991, Analytical biochemistry.

MECHANISTIC STUDIES ON THE INHIBITION OF CYTOCHROME P-450-MEDIATED MIXED FUNCTION OXIDATION

C. Marcus, C. F. Wilkinson, M. Murray, 1983 .

Methylenedioxyphenyl complexes with microsomal cytochrome P-450: In vivo complex formation in rat liver and in midgut tissues of the Southern armyworm (Spodoptera eridania)

C. Marcus, C. F. Wilkinson, M. Murray, 1987 .

Cytochrome P450 1B1 expression in human malignant tumours.

J. McKay, G. Murray, C. Marcus, 1996, Biochemical Society transactions.

Retraction: HSP90 Inhibitors Suppress Aryl Hydrocarbon Receptor-Mediated Activation of CYP1A1 and CYP1B1 Transcription and DNA Adduct Formation.

K. Subbaramaiah, A. Dannenberg, C. Marcus, 2022, Cancer prevention research.

Induction of AHR Signaling in Response to the Indolimine Class of Microbial Stress Metabolites

Imhoi Koo, G. Perdew, A. Annalora, 2023, Metabolites.

A novel adrenocorticotropin-inducible cytochrome P450 from rat adrenal microsomes catalyzes polycyclic aromatic hydrocarbon metabolism.

C. Jefcoate, C. Marcus, C. Pidgeon, 1991, Endocrinology.

Alternative Splicing in the Nuclear Receptor Superfamily Redirects Human Metabolic Homeostasis

P. Iversen, A. Annalora, C. Marcus, 2020 .

CYP1B1 expression promotes the proangiogenic phenotype of endothelium through decreased intracellular oxidative stress and thrombospondin-2 expression.

C. Sorenson, N. Sheibani, C. Jefcoate, 2009, Blood.

Binding of benzo[a]pyrene by purified cytochrome P-450c.

C. Jefcoate, C. Marcus, C. Turner, 1985, Biochemistry.