B. Bierer

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Preparing for responsible sharing of clinical trial data.

Mark Barnes, M. Mello, Jeffrey K Francer, 2013, The New England journal of medicine.

Using Social Media as a Research Recruitment Tool: Ethical Issues and Recommendations

Holly Fernandez Lynch, I Glenn Cohen, Robin Pierce, 2017, The American journal of bioethics : AJOB.

Revised 'Common Rule' Shapes Protections For Research Participants.

B. Bierer, Mark Barnes, H. Lynch, 2017, Health affairs.

Physician self-assessment of leadership skills.

G. McMahon, A. V. von Keudell, M. B. Harris, 2014, Physician executive.

Advancing Health Literacy in Clinical Research: Clear Communications for Every Participant.

Christopher R. Trudeau, Sylvia Baedorf Kassis, B. Bierer, 2019, NAM perspectives.

Hydroxychloroquine/chloroquine for the treatment of hospitalized patients with COVID-19: An individual participant data meta-analysis

Elizabeth L. Ogburn, W. Self, E. Ogburn, 2022, medRxiv.

Interleukin 2 stimulation of p70 S6 kinase activity is inhibited by the immunosuppressant rapamycin.

C. Crews, V. Calvo, B. Bierer, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Up‐regulation of HIV coreceptor CXCR4 expression in human T lymphocytes is mediated in part by a cAMP‐responsive element

D. Dimitrov, R. Dewar, B. Bierer, 2002, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Ex Vivo Rapamycin Generates Donor Th2 Cells That Potently Inhibit Graft-versus-Host Disease and Graft-versus-Tumor Effects via an IL-4-Dependent Mechanism1

B. Bierer, M. Eckhaus, D. Fowler, 2005, The Journal of Immunology.

A study of induced hyponatremia in the prevention and treatment of sickle-cell crisis.

F. Epstein, B. Bierer, H. Bunn, 1980, The New England journal of medicine.

Navigating the ethics of remote research data collection

B. Bierer, L. Gelinas, S. White, 2021, Clinical trials.

Building Workforce Capacity Abroad While Strengthening Global Health Programs at Home: Participation of Seven Harvard-Affiliated Institutions in a Health Professional Training Initiative in Rwanda

D. Milner, P. Farmer, A. Binagwaho, 2017, Academic medicine : journal of the Association of American Medical Colleges.

Sialophorin, a surface sialoglycoprotein defective in the Wiskott- Aldrich syndrome, is involved in human T lymphocyte proliferation

B. Bierer, S. Burakoff, S. Mentzer, 1987, The Journal of experimental medicine.

The biologic roles of CD2, CD4, and CD8 in T-cell activation.

S. Ratnofsky, B. Bierer, B. Sleckman, 1989, Annual review of immunology.

CD43, a molecule defective in Wiskott-Aldrich syndrome, binds ICAM-1

W. Hahn, B. Bierer, John K. Park, 1991, Nature.

Enhancement of T-cell activation by the CD43 molecule whose expression is defective in Wiskott–Aldrich syndrome

B. Bierer, John K. Park, S. Burakoff, 1991, Nature.

Characterization of Informed Consent Forms Posted on ClinicalTrials.gov

D. Zarin, Tony Tse, B. Bierer, 2021, JAMA network open.

Time for NIH to lead on data sharing

A. Butte, I. Sim, H. Krumholz, 2020, Science.

Cloning and Characterization of N4WBP5A, an Inducible, Cyclosporine-sensitive, Nedd4-binding Protein in Human T Lymphocytes*

B. Bierer, L. Nie, A. Cristillo, 2003, Journal of Biological Chemistry.

T-lymphocyte coactivator molecules.

B. Bierer, L. Salazar-Fontana, 2001, Current opinion in hematology.

Expression of human interleukin-3 (multi-CSF) is restricted to human lymphocytes and T-cell tumor lines.

C. Niemeyer, B. Bierer, B. Mathey-Prevot, 1989, Blood.

Responsibilities of Data Monitoring Committees: Consensus Recommendations

Jonathan H Seltzer, J. Wittes, L. Sleeper, 2016, Therapeutic innovation & regulatory science.

Phenotypic and functional characterization of human cytolytic T cells lacking expression of CD5.

B. Bierer, S. Burakoff, B. Smith, 1988, The Journal of clinical investigation.

Allocation of Opportunities to Participate in Clinical Trials during the Covid-19 Pandemic and Other Public Health Emergencies.

B. Wilfond, M. Meyer, R. Sharp, 2021, The Hastings Center report.

Testing approaches to sharing trial results with participants: The Show RESPECT cluster randomised, factorial, mixed methods trial

William J. Cragg, M. Sydes, A. Copas, 2021, PLoS medicine.

Economic vulnerability and payment for research participation

B. Bierer, L. Gelinas, S. White, 2020, Clinical trials.

Overlapping but nonidentical binding sites on CD2 for CD58 and a second ligand CD59.

W. Hahn, B. Bierer, A. Bothwell, 1992, Science.

Scientific Merit Predicates Ethical Review of Clinical Research.

B. Bierer, L. Gelinas, 2019, Ethics & human research.

Selective depletion of bone marrow T lymphocytes with anti-CD5 monoclonal antibodies: effective prophylaxis for graft-versus-host disease in patients with hematologic malignancies.

R. Macklis, E. Guinan, D. Golan, 1991, Blood.

A distinct cytoplasmic domain of CD2 regulates ligand avidity and T-cell responsiveness to antigen.

W. Hahn, V. Calvo, B. Bierer, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Lateral mobility of class I histocompatibility antigens in B lymphoblastoid cell membranes: modulation by cross-linking and effect of cell density

D. Golan, B. Bierer, S. Herrmann, 1987, The Journal of cell biology.

Calcium‐ and FK506‐independent interaction between the immunophilin FKBP51 and calcineurin *

S. Baksh, B. Bierer, A. Cristillo, 2002 .

The effect of the immunosuppressant FK‐506 on alternate pathways of T cell activation

S. Schreiber, B. Bierer, S. Burakoff, 1991, European journal of immunology.

Molecular cloning of a membrane-associated human FK506- and rapamycin-binding protein, FKBP-13.

S. Schreiber, William Arbuthnot Sir Lane, M. Albers, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Recent advances in immunosuppression

B. Bierer, Amy C. Vander Woude, 1995 .

Rapamycin and FK506 binding proteins (immunophilins)

S. Schreiber, William Arbuthnot Sir Lane, H. Fretz, 1991 .

Differential chemokine expression profiles in human peripheral blood T lymphocytes: dependence on T-cell coreceptor and calcineurin signaling.

B. Bierer, A. Cristillo, M. Macri, 2003, Blood.

Regulation of CXCR4 expression in human T lymphocytes by calcium and calcineurin.

B. Bierer, A. Cristillo, 2003, Molecular immunology.

Identification of Novel Targets of Immunosuppressive Agents by cDNA-based Microarray Analysis*

B. Bierer, A. Cristillo, 2002, The Journal of Biological Chemistry.

Molecular and biological actions of cyclosporin A and FK506 on T cell development and function.

G. Holländer, B. Bierer, S. Burakoff, 1994, Transfusion science.

Inhibition of calcineurin phosphatase activity in adult bone marrow transplant patients treated with cyclosporine A.

D. Neuberg, S. Pai, D. Fruman, 1994, Blood.

Activation of 70‐kDa S6 kinase, induced by the cytokines interleukin‐3 and erythropoietin and inhibited by rapamycin, is not an absolute requirement for cell proliferation

V. Calvo, B. Bierer, C. Gjertson, 1994, European journal of immunology.

CD80 and CD86 Are Not Equivalent in Their Ability to Induce the Tyrosine Phosphorylation of CD28*

J. Hutchcroft, B. Bierer, J. Slavik, 1999, The Journal of Biological Chemistry.

Activation-dependent phosphorylation of the T-lymphocyte surface receptor CD28 and associated proteins.

J. Hutchcroft, B. Bierer, Barbara E. Bierer, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Animal Models for Tumor Immunology

B. Bierer, 2009 .

Animal Models for Tumor Immunology

B. Bierer, 2009 .

Animal Models for Tumor Immunology

B. Bierer, 2008 .

Animal Models for Tumor Immunology

B. Bierer, 2005 .

Synergistic T cell activation via the physiological ligands for CD2 and the T cell receptor

B. Bierer, S. Herrmann, S. Burakoff, 1988, The Journal of experimental medicine.

The effect of desferrithiocin, an oral iron chelator, on T-cell function.

B. Bierer, D. Nathan, D. G. Nathan, 1990, Blood.

A monoclonal antibody to LFA‐3, the CD2 ligand, specifically immobilizes major histocompatibility complex proteins

D. Golan, B. Bierer, S. Herrmann, 1989, European journal of immunology.

Expression and function of a CD 5 cDNA in human and murine T cells

J. Strominger, Y. Nishimura, B. Bierer, 1988, European journal of immunology.

The Role of Co-receptors in T Cell Activation

W. Hahn, T. Collins, B. Bierer, 1993 .

CD4, CD8 and CD2 in T cell adhesion and signaling.

T. L. Collins, W. Hahn, B. Bierer, 1993, Current topics in microbiology and immunology.

T‐Lymphocyte Activation: The Biology and Function of CD2 and CD4

B. Bierer, S. Burakoff, 1989, Immunological reviews.

THE BIOLOGIC ROLES OF CD2

B. Bierer, B. Sleckman, E. Ra, 1989 .

T cell adhesion molecules

B. Bierer, S. Burakoff, 1988, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

T3 glycoprotein is functional although structurally distinct on human T-cell receptor gamma T lymphocytes.

J. Mclean, J. Strominger, M. Krangel, 1987, Proceedings of the National Academy of Sciences of the United States of America.

Cell-mediated immunity.

B. Bierer, J. Goust, 1993, Immunology series.

Signaling via LAT (linker for T-cell activation) and Syk/ZAP70 is required for ERK activation and NFAT transcriptional activation following CD2 stimulation.

H. Lin, L. Samelson, B. Bierer, 2000, Blood.

Rapamycin: Biological and therapeutic effects, binding by immunophilins and molecular targets of action

B. Bierer, Michael A. Wood, 1994 .

The SMART IRB platform: A national resource for IRB review for multisite studies

D. MacFadden, B. Bierer, Lee M Nadler, 2019, Journal of Clinical and Translational Science.

Cross‐linking CD28 leads to activation of 70‐kDa S6 kinase

S. Pai, V. Calvo, B. Bierer, 1994, European journal of immunology.

Suppression of human IL-1β, IL-2, IFN-γ, and TNF-α production by cigarette smoke extracts

B. Bierer, B. Freed, Y. Ouyang, 2000 .

Competitive inhibition of calcineurin phosphatase activity by its autoinhibitory domain.

C. Walsh, D. Fruman, S. Wesselborg, 1996, The Biochemical journal.

T Cell Regulation of p62 dok (Dok1) Association with Crk-L*

B. Bierer, M. Martelli, M. Bu, 2001, The Journal of Biological Chemistry.

Biology of cyclosporin A and FK506.

B. Bierer, 1994, Progress in clinical and biological research.

Suppression of human IL-1beta, IL-2, IFN-gamma, and TNF-alpha production by cigarette smoke extracts.

B. Bierer, B. Freed, Y. Ouyang, 2000, The Journal of allergy and clinical immunology.

Disease and Graft-versus-Tumor Effects via Graft-versus-Host Cells That Potently Inhibit Ex Vivo Rapamycin Generates Donor Th2

B. Bierer, M. Eckhaus, D. Fowler, 2013 .

IL-4-Dependent Mechanism Disease and Graft-versus-Tumor Effects via Graft-versus-HostCells That Potently Inhibit Ex Vivo Rapamycin Generates Donor Th 2

B. Bierer, M. Eckhaus, D. Fowler, 2005 .

Transparency and Clinical Trial Data Sharing

B. Bierer, Mark Barnes, Rebecca Li, 2019, Transparency in Health and Health Care in the United States.

Patient voice in clinical trial programs in industry

Sylvia Baedorf Kassis, B. Bierer, N. Richie, 2021, Pragmatic Randomized Clinical Trials.

Expression of the T-cell surface molecule CD2 and an epitope-loss CD2 mutant to define the role of lymphocyte function-associated antigen 3 (LFA-3) in T-cell activation.

B. Seed, B. Bierer, S. Burakoff, 1988, Proceedings of the National Academy of Sciences of the United States of America.

Advancing the inclusion of underrepresented women in clinical research

B. Bierer, S. White, Laura G. Meloney, 2022, Cell reports. Medicine.

Failure of gelsolin overexpression to regulate lymphocyte apoptosis.

D. Kwiatkowski, B. Bierer, M. Martelli, 2000, Blood.

Gelsolin overexpression alters actin dynamics and tyrosine phosphorylation of lipid raft-associated proteins in Jurkat T cells.

B. Bierer, S. Bunnell, G. Sun, 2007, Molecular immunology.

The Harvard Catalyst Common Reciprocal IRB Reliance Agreement: An Innovative Approach to Multisite IRB Review and Oversight

B. Bierer, Sabune Winkler, Elizabeth Witte, 2015, Clinical and translational science.

Fair payment and just benefits to enhance diversity in clinical research

B. Bierer, L. Gelinas, D. Strauss, 2021, Journal of Clinical and Translational Science.

Differences between CEM and human peripheral blood T lymphocytes in cAMP-dependent HIV viral fusion and CXCR4 expression.

D. Dimitrov, Regina Campbell-Malone, B. Bierer, 2002, Experimental and molecular pathology.

Abnormal cytolytic activity of lymphocyte function-associated antigen-1-deficient human cytolytic T lymphocyte clones.

T. Springer, B. Bierer, D. Anderson, 1986, The Journal of clinical investigation.

T cell receptor activation of a ribosomal S6 kinase activity

V. Calvo, B. Bierer, T. Vik, 1992, European journal of immunology.

Small Rho GTPase Cdc42 in Human T Cellsthe Polymerization Through the Activation of CD28 Engagement Promotes Actin

V. Barr, B. Bierer, L. Salazar-Fontana, 2003 .

Gene immunotherapy in murine acute myeloid leukemia: granulocyte-macrophage colony-stimulating factor tumor cell vaccines elicit more potent antitumor immunity compared with B7 family and other cytokine vaccines.

G. Dranoff, B. Bierer, H. Weinstein, 1998, Blood.

Steps toward a System of IRB Precedent: Piloting Approaches to Summarizing IRB Decisions for Future Use.

B. Bierer, H. Lynch, C. Coleman, 2021, Ethics & human research.

Intracellular mediators regulate CD2 lateral diffusion and cytoplasmic Ca2+ mobilization upon CD2-mediated T cell activation.

W. Hahn, D. Golan, B. Bierer, 1995, Biophysical journal.

Separable portions of the CD2 cytoplasmic domain involved in signaling and ligand avidity regulation

W. Hahn, B. Bierer, 1993, The Journal of experimental medicine.

The Induction of An Immune Response: Antigens, Lymphocytes, And Accesory Cells

B. Bierer, G. Virella, 2001 .

Recombinant human interleukin-1 receptor antagonist in the treatment of steroid-resistant graft-versus-host disease.

K. Ballen, B. Bierer, H. Weinstein, 1994, Blood.

FK506 (Tacrolimus) monotherapy for prevention of graft-versus-host disease after histocompatible sibling allogenic bone marrow transplantation.

R. Collins, J. Fay, J. Wingard, 1996, Blood.

Functional Analysis of Cd2, cd4, and cd8 in t‐Cell Activation a

B. Seed, S. Ratnofsky, B. Bierer, 1988, Annals of the New York Academy of Sciences.

Humoral hypercalcemia of malignancy. Release of a prostaglandin-stimulating bone-resorbing factor in vitro by human transitional-cell carcinoma cells.

B. Bierer, G. Segre, F. R. Bringhurst, 1986, The Journal of clinical investigation.

Signaling through CD28/CTLA-4 family receptors: puzzling participation of phosphatidylinositol-3 kinase.

J. Hutchcroft, B. Bierer, 1996, Journal of immunology.

Effects of cyclosporin A and FK506 on Fc epsilon receptor type I-initiated increases in cytokine mRNA in mouse bone marrow-derived progenitor mast cells: resistance to FK506 is associated with a deficiency in FK506-binding protein FKBP12.

S. Schreiber, C. Walsh, D. Fruman, 1992, Proceedings of the National Academy of Sciences of the United States of America.

The complete sequences of plasmids pFNeo and pMH-Neo: convenient expression vectors for high-level expression of eukaryotic genes in hematopoietic cell lines.

W. Hahn, T. Saito, R. Germain, 1993, Gene.

FK 506 ( Tacrolimus ) Monotherapy for Prevention of Graft-Versus-Host Disease After Histocompatible Sibling Allogeneic Bone Marrow Transplantation

R. Collins, J. Fay, J. Wingard, 2002 .

Signal transduction pathways involved in T cell receptor-induced regulation of CD2 avidity for CD58.

W. Hahn, B. Bierer, S. Burakoff, 1993, Journal of immunology.

Rethinking ethical oversight in the era of the learning health system.

Sarah M. Greene, D. Asch, T. Lieu, 2020, Healthcare.

Interaction of CD2 with its ligand, LFA-3, in human T cell proliferation.

B. Bierer, S. Herrmann, S. Burakoff, 1988, Journal of immunology.

Treatment of chronic graft-versus-host disease with clofazimine.

B. Bierer, J. Antin, S. Lee, 1997, Blood.

Expression of CD5 regulates responsiveness to IL-1.

B. Bierer, S. Burakoff, Y. Nishimura, 1988, Journal of immunology.

Universal Funder Responsibilities That Advance Social Value

D. Zarin, B. Bierer, D. Strauss, 2018, The American journal of bioethics : AJOB.

The Decision to Enroll in a Clinical Trial Should Be Unencumbered

B. Bierer, L. Gelinas, 2020 .

Two distinct signal transmission pathways in T lymphocytes are inhibited by complexes formed between an immunophilin and either FK506 or rapamycin.

L A Herzenberg, R F Standaert, S. Schreiber, 1990, Proceedings of the National Academy of Sciences of the United States of America.

Actin Stabilization by Jasplakinolide Enhances Apoptosis Induced by Cytokine Deprivation*

B. Bierer, S. Posey, Celeste Posey, 1999, The Journal of Biological Chemistry.

Sharing and reuse of individual participant data from clinical trials: principles and recommendations

Dipak Kalra, Rachel L Knowles, Christian Ohmann, 2017, BMJ Open.

J. Coligan, D. Margulies, E. Shevach, 2012 .

Immunosuppressants FK506 and rapamycin function as reversal agents of the multidrug resistance phenotype.

B. Bierer, K. Stieglitz, R. Arceci, 1992, Blood.

Identification of a Physical Interaction between Calcineurin and Nuclear Factor of Activated T Cells (NFATp) (*)

D. Fruman, S. Wesselborg, B. Bierer, 1996, The Journal of Biological Chemistry.

Cyclosporin A and FK506: molecular mechanisms of immunosuppression and probes for transplantation biology.

D. Fruman, G. Holländer, B. Bierer, 1993, Current opinion in immunology.

Correlation of calcineurin phosphatase activity and programmed cell death in murine T cell hybridomas

D. Fruman, B. Bierer, S. Burakoff, 1992, European journal of immunology.

Calcineurin phosphatase activity in T lymphocytes is inhibited by FK 506 and cyclosporin A.

C. Klee, D. Fruman, B. Bierer, 1992, Proceedings of the National Academy of Sciences of the United States of America.

CD28 Engagement Promotes Actin Polymerization Through the Activation of the Small Rho GTPase Cdc42 in Human T Cells

V. Barr, L. Samelson, B. Bierer, 2003, The Journal of Immunology.

Rapamycin-induced inhibition of the 70-kilodalton S6 protein kinase.

J. Avruch, V. Calvo, B. Bierer, 1992, Science.

Molecular cloning of a 25-kDa high affinity rapamycin binding protein, FKBP25.

B. Bierer, S. Burakoff, Y. J. Jin, 1992, The Journal of biological chemistry.

FK506 binding protein 12 mediates sensitivity to both FK506 and rapamycin in murine mast cells

D. Fruman, B. Bierer, S. Burakoff, 1995, European journal of immunology.

Immunophilins in protein folding and immunosuppression 1

D. Fruman, B. Bierer, S. Burakoff, 1994, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Structural organization of the genes encoding human and murine FK506-binding protein (FKBP) 13 and comparison to FKBP1.

A. Dilella, W. Zhang, R. J. Craig, 1993, Gene.

Yeast Bim1p Promotes the G1-specific Dynamics of Microtubules

E. O'Toole, D. Pellman, B. Bierer, 1999, The Journal of cell biology.

The APC-associated protein EB1 associates with components of the dynactin complex and cytoplasmic dynein intermediate chain

Barbara E. Bierer, David Pellman, D. Pellman, 1999, Current Biology.

The adenomatous polyposis coli-binding protein EB1 is associated with cytoplasmic and spindle microtubules.

D. Pellman, B. Bierer, S. C. Schuyler, 1998, Proceedings of the National Academy of Sciences of the United States of America.

T cell signal transfuction and the role of CD7 in costimulation

B. Bierer, Ross Stillwell, 2001, Immunologic research.

When clinical trials compete: prioritising study recruitment

I. Cohen, B. Bierer, H. Lynch, 2017, Journal of Medical Ethics.

CD28/CTLA-4 and CD80/CD86 families

J. Hutchcroft, B. Bierer, J. Slavik, 1999, Immunologic research.

Eb1 Proteins Regulate Microtubule Dynamics, Cell Polarity, and Chromosome Stability

B. Bierer, J. S. Tirnauer, 2000, The Journal of cell biology.

A Descriptive-Multivariate Analysis of Community Knowledge, Confidence, and Trust in COVID-19 Clinical Trials among Healthcare Workers in Uganda

Khalid J. Alzahrani, A. Laudisoit, L. DeTora, 2021, Vaccines.

The actin cytoskeleton, membrane lipid microdomains, and T cell signal transduction.

B. Bierer, S. C. Morley, 2001, Advances in immunology.

The involvement of the proto-oncogene p120 c-Cbl and ZAP-70 in CD2-mediated T cell activation.

B. Bierer, M. Martelli, H. Lin, 2001, International immunology.

A Framework for Ethical Payment to Research Participants

I. Cohen, B. Bierer, H. Lynch, 2018, The New England journal of medicine.

Recombinant human interleukin-1 receptor antagonist in the treatment of steroid-resistant graft-versus-host disease

E. Guinan, K. Ballen, B. Bierer, 1994 .

REGULATION OF CYTOTOXIC T LYMPHOCYTE‐MEDIATED GRAFT REJECTION FOLLOWING BONE MARROW

B. Smith, B. Bierer, S. Emerson, 1988, Transplantation.

A Large Proportion of T Lymphocytes Lack CD5 Expression After Bone Marrow Transplantation

B. Smith, B. Bierer, S. Burakoff, 1989 .

The interaction of CD2 with its LFA-3 ligand expressed by autologous erythrocytes results in enhancement of B cell responses.

B. Bierer, M. Rugeles, B. Hyman, 1988, Cellular immunology.

A large proportion of T lymphocytes lack CD5 expression after bone marrow transplantation.

B. Bierer, S. Burakoff, B. Smith, 1989, Blood.

Dental Care in Times of the COVID-19 Pandemic: A Review

M. Tovani-Palone, L. DeTora, B. Bierer, 2021, Medical sciences.

Characterization of HTLV-I in vivo infected T cell clones. IL-2-independent growth of nontransformed T cells.

D. Hafler, K. Wucherpfennig, P. Höllsberg, 1992, Journal of immunology.

Disruptive and avoidable: GDPR challenges to secondary research uses of data

B. Bierer, Mark Barnes, M. Dimaio, 2020, European Journal of Human Genetics.

Ethical Challenges in Clinical Research During the COVID-19 Pandemic

B. Bierer, L. Gelinas, S. White, 2020, Journal of Bioethical Inquiry.

A role for calcineurin in degranulation of murine cytotoxic T lymphocytes.

D. Fruman, B. Bierer, S. Burakoff, 1993, Journal of immunology.

T cell receptors: adhesion and signaling.

B. Bierer, S. Burakoff, 1991, Advances in cancer research.

Association of CD2 with tubulin. Evidence for a role of the cytoskeleton in T cell activation.

R. Offringa, B. Bierer, 1993, The Journal of biological chemistry.

Uncoupling activation-dependent HS1 phosphorylation from nuclear factor of activated T cells transcriptional activation in Jurkat T cells: differential signaling through CD3 and the costimulatory receptors CD2 and CD28.

J. Hutchcroft, B. Bierer, T. Watanabe, 1998, Journal of immunology.

Receptors CD 2 and CD 28 Through CD 3 and the Costimulatory in Jurkat T Cells : Differential Signaling Activated T Cells Transcriptional Activation Phosphorylation from Nuclear Factor of Uncoupling Activation-Dependent HS 1

J. Hutchcroft, B. Bierer, J. Slavik, 1998 .

Identification of a Proline-Rich Sequence in the CD2 Cytoplasmic Domain Critical for Regulation of Integrin-Mediated Adhesion and Activation of Phosphoinositide 3-Kinase

B. Bierer, Y. Shimizu, T. Zell, 1998, Molecular and Cellular Biology.

Association of p59 fyn with the T Lymphocyte Costimulatory Receptor CD2

J. Hutchcroft, H. Band, B. Bierer, 1998, The Journal of Biological Chemistry.

Functional CD2 mutants unable to bind to, or be stimulated by, LFA-3.

B. Bierer, S. Burakoff, H. Wolff, 1990, Journal of immunology.

Partial deletions of the cytoplasmic domain of CD2 result in a partial defect in signal transduction.

B. Bierer, S. Burakoff, R. Bogart, 1990, Journal of immunology.

Adhesion receptors in lymphocyte activation.

T. L. Collins, B. Bierer, P. Kassner, 1994, Current opinion in immunology.

Localization of the FK506-binding protein, FKBP 13, to the lumen of the endoplasmic reticulum.

B. Bierer, S. Nigam, S. Burakoff, 1993, The Biochemical journal.

Inhibition of actin polymerization enhances commitment to and execution of apoptosis induced by withdrawal of trophic support

B. Bierer, G. Sun, S. Celeste Morley, 2003, Journal of cellular biochemistry.

Cyclosporin A, FK506, and rapamycin: binding to immunophilins and biological action.

B. Bierer, 1994, Chemical immunology.

Characterization of a mutant calcineurin A alpha gene expressed by EL4 lymphoma cells

S. Pai, D. Fruman, B. Bierer, 1995, Molecular and cellular biology.

History of Animal Plagues of North America. With an Occasional Reference to Other Diseases and Diseased Conditions. Part 1, Part 2, Part 3, Part 4 and Part 5.

B. Bierer, 1939 .

Rapamycin inhibits clonal expansion and adipogenic differentiation of 3T3-L1 cells.

W. Yeh, B. Bierer, S. McKnight, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Standards for Clinical Research: Keeping Pace With the Technology of the Future.

E. Antman, B. Bierer, 2016, Circulation.

Protecting Pregnant Women With Substance Use Disorders and Their Neonates Participating in Research.

J. Davis, B. Bierer, L. Yao, 2019, JAMA.

Data Authorship as an Incentive to Data Sharing.

Mercè Crosas, B. Bierer, M. Crosas, 2017, The New England journal of medicine.

A Global, Neutral Platform for Sharing Trial Data.

Mark Barnes, Rebecca Li, B. Bierer, 2016, The New England journal of medicine.

Truth in Advertising

I. Cohen, B. Bierer, H. Lynch, 2018, Therapeutic innovation & regulatory science.

Justice, diversity, and research ethics review

B. Bierer, D. Strauss, S. White, 2021, Science.

Reimagining Health Data Exchange: An Application Programming Interface–Enabled Roadmap for India

Kenneth D Mandl, Tarun Khanna, Adrian Gropper, 2018, Journal of medical Internet research.

Disruption of T cell development and repertoire selection by calcineurin inhibition in vivo.

D. Fruman, G. Holländer, B. Bierer, 1994, Transplantation.

Q-T prolongation and torsades de pointes ventricular tachycardia produced by the tetracyclic antidepressant agent maprotiline.

H. Herrmann, B. Bierer, L. Kaplan, 1983, The American journal of cardiology.

Credit data generators for data reuse

Barbara E. Bierer, Heather H. Pierce, Anurupa Dev, 2019, Nature.

Forensic bitemark identification: weak foundations, exaggerated claims

Stephen E. Fienberg, Hal Stern, William C. Thompson, 2016, Journal of law and the biosciences.

Incorporating ethical principles into clinical research protocols: a tool for protocol writers and ethics committees

Jacquelyn Murphy, Marc Wilenzick, B. Bierer, 2016, Journal of Medical Ethics.

Committing to the Inclusion of Diverse Populations in Clinical Research

B. Bierer, D. Strauss, Hayat Ahmed, 2020, Therapeutic Innovation & Regulatory Science.

Credit data generators for data reuse

A. Dev, B. Bierer, Heather H Pierce, 2019, Nature.

Evaluating the frequency of English language requirements in clinical trial eligibility criteria: A systematic analysis using ClinicalTrials.gov

B. Bierer, W. Morrell, A. Muthukumar, 2021, PLoS medicine.

Data visualization explorer: A tool for participant representation in pivotal trials of FDA-approved medicinal products

B. Bierer, Laura G Meloney, Ariel B. Carmeli, 2023, Patterns.

Patient-reported safety and quality of care in outpatient oncology.

Patricia Reid Ponte, Saul N Weingart, S. Weingart, 2007, Joint Commission journal on quality and patient safety.

Research Subject Injury Compensation: The Ongoing Search for Fairness, Consistency and Clarity

B. Bierer, Mark Barnes, J. Flaherty, 2019, Journal of Law, Medicine & Ethics.

Data Authorship as an Incentive to Data Sharing.

Mercè Crosas, Barbara E. Bierer, Heather H. Pierce, 2017, The New England journal of medicine.

Returning aggregate results of clinical trials: Empirical data of patient preferences

J. Ligibel, B. Bierer, J. Denninger, 2018, Journal of Clinical and Translational Science.

Differential Phosphorylation of the T Lymphocyte Costimulatory Receptor CD28

J. Hutchcroft, B. Bierer, B. Tsai, 1996, The Journal of Biological Chemistry.

Identification and characterization of an immunophilin expressed during the clonal expansion phase of adipocyte differentiation.

W. Yeh, B. Bierer, T. Li, 1995, Proceedings of the National Academy of Sciences of the United States of America.

An ethics framework for consolidating and prioritizing COVID-19 clinical trials

B. Wilfond, M. Meyer, R. Sharp, 2021, Clinical trials.

Leveling the Joint Task Force Core Competencies for Clinical Research Professionals

B. Bierer, S. Sonstein, R. N. Namenek Brouwer, 2018, Therapeutic Innovation & Regulatory Science.

Leveling the Joint Task Force Core Competencies for Clinical Research Professionals

B. Bierer, S. Sonstein, H. R. Kolb, 2018, Therapeutic innovation & regulatory science.

The complex of FK506-binding protein 12 and FK506 inhibits calcineurin phosphatase activity and IgE activation-induced cytokine transcripts, but not exocytosis, in mouse mast cells.

D. Fruman, K. Austen, B. Bierer, 1995, Journal of immunology.

T cell adhesion, avidity regulation and signaling: a molecular analysis of CD2.

W. Hahn, B. Bierer, 1993, Seminars in immunology.

Disruptive and avoidable: GDPR challenges to secondary research uses of data

B. Bierer, Mark Barnes, M. Dimaio, 2020, European Journal of Human Genetics.

How to fix the GDPR's frustration of global biomedical research

Mark Barnes, Bartha Maria Knoppers, David Peloquin, 2020, Science.

Applying Civil Rights Law to Clinical Research: Title VI’s Equal Access Mandate

B. Bierer, M. Barnes, David Péloquin, 2022, Journal of Law, Medicine & Ethics.

Institutions as an ethical locus of research prioritisation

I. Cohen, B. Bierer, H. Lynch, 2017, Journal of Medical Ethics.

Primed to comply: Individual participant data sharing statements on ClinicalTrials.gov

B. Bierer, S. White, Emily E Statham, 2020, PloS one.

Issues in the Registration of Database Studies.

W. Crown, D. Zarin, B. Bierer, 2020, Journal of clinical epidemiology.

Phorbol ester treatment inhibits phosphatidylinositol 3-kinase activation by, and association with, CD28, a T-lymphocyte surface receptor.

J. Hutchcroft, B. Tsai, L. Varticovski, 1995, Proceedings of the National Academy of Sciences of the United States of America.

High-dose cyclophosphamide, carmustine, and etoposide with autologous transplantation in Hodgkin's disease: a prognostic model for treatment outcomes.

Shaun Parsons, E. Guinan, P. Mauch, 1997, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Enhancing Safety Reporting in Adult Ambulatory Oncology With a Clinician Champion: A Practice Innovation

S. Weingart, B. Bierer, P. R. Ponte, 2009, Journal of nursing care quality.

Interaction of CD2 with its ligand lymphocyte function-associated antigen-3 induces adenosine 3',5'-cyclic monophosphate production in T lymphocytes.

W. Hahn, B. Bierer, S. Burakoff, 1991, Journal of immunology.

Nonexceptionalism, Research Risks, and Social Media: Response to Open Peer Commentaries on “Using Social Media as a Research Recruitment Tool: Ethical Issues and Recommendations”

B. Bierer, H. Lynch, Sabune Winkler, 2017, American Journal of Bioethics.

Sharing and reuse of individual participant data from clinical trials: principles and recommendations

C. Ohmann, H. Sitter, C. Tudur-Smith, 2017, BMJ Open.

What do revised U.S. rules mean for human research?

Martha F. Jones, Suzanne M. Rivera, B. Bierer, 2017, Science.

Responsibilities of Data Monitoring Committees: Consensus Recommendations

Jonathan H Seltzer, J. Wittes, L. Sleeper, 2016, Therapeutic innovation & regulatory science.

Online Research Participant Communication: Balancing Benefits and Risks.

B. Bierer, W. Morrell, Luke Gelinas, 2021, Ethics & human research.

Assessment of a shortened informed consent form for pediatric research: a pilot study

S. Hirschfeld, J. Davis, B. Bierer, 2018, Pediatric Research.