D. Benjamin

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Evidence-based guidelines for pediatric clinical trials: focus on StaR Child Health

M. Sampson, D. Benjamin, M. Cohen-Wolkowiez, 2012, Expert review of clinical pharmacology.

Electronic Health Records and Pharmacokinetic Modeling to Assess the Relationship between Ampicillin Exposure and Seizure Risk in Neonates.

M. Pencina, P. Smith, A. Tremoulet, 2016, The Journal of pediatrics.

Population Analysis of Anidulafungin in Infants to Older Adults With Confirmed or Suspected Invasive Candidiasis

D. Benjamin, M. Cohen-Wolkowiez, L. Mcfadyen, 2020, Clinical pharmacology and therapeutics.

Results From a Prospective, International, Epidemiologic Study of Invasive Candidiasis in Children and Neonates

D. Benjamin, T. Walsh, A. Velegraki, 2012, The Pediatric infectious disease journal.

Comparison of costs, length of stay, and mortality associated with Candida glabrata and Candida albicans bloodstream infections.

D. Benjamin, S. Reed, C. Moran, 2010, American journal of infection control.

CANDIDA ALBICANS AND NON-ALBICANS BLOODSTREAM INFECTIONS IN ADULT AND PEDIATRIC PATIENTS: COMPARISON OF MORTALITY AND COSTS

D. Benjamin, S. Reed, C. Moran, 2009, The Pediatric infectious disease journal.

Pediatric antifungal agents

D. Benjamin, M. Cohen-Wolkowiez, C. Moran, 2009, Current opinion in infectious diseases.

Pediatric Antibacterial and Antifungal Trials From 2007 to 2017

J. Thaden, E. Tsalik, P. Smith, 2018, Pediatrics.

First Dose in Neonates: Are Juvenile Mice, Adults and In Vitro–In Silico Data Predictive of Neonatal Pharmacokinetics of Fluconazole

B. Matrot, D. Benjamin, K. Watt, 2014, Clinical Pharmacokinetics.

In Vitro Investigation of the Hepatobiliary Disposition Mechanisms of the Antifungal Agent Micafungin in Humans and Rats

K. Brouwer, D. Benjamin, P. Annaert, 2010, Drug Metabolism and Disposition.

Prolonged Duration of Initial Empirical Antibiotic Treatment Is Associated With Increased Rates of Necrotizing Enterocolitis and Death for Extremely Low Birth Weight Infants

B. Stoll, N. Hansen, P. Sánchez, 2009, Pediatrics.

Risk factors for hematogenous complications of intravascular catheter-associated Staphylococcus aureus bacteremia.

C. Woods, V. Fowler, N. Day, 2005, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Infections due to Aspergillus terreus: a multicenter retrospective analysis of 83 cases.

J. Perfect, H. Jafri, D. Benjamin, 2004, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Value of an inhalational model of invasive aspergillosis.

W. M. Foster, A. Zaas, J. Perfect, 2004, Medical mycology.

Population Pharmacokinetics of Intravenous Acyclovir in Preterm and Term Infants

P. Smith, M. Sampson, D. Benjamin, 2013, The Pediatric infectious disease journal.

Dosing of Antimicrobials in the Neonatal Intensive Care Unit

M. Laughon, P. Smith, D. Benjamin, 2020, The Pediatric infectious disease journal.

Characterization of the Population Pharmacokinetics of Ampicillin in Neonates Using an Opportunistic Study Design

B. Poindexter, M. Laughon, A. Tremoulet, 2014, Antimicrobial Agents and Chemotherapy.

Developmental Pharmacokinetics of Piperacillin and Tazobactam Using Plasma and Dried Blood Spots from Infants

B. Poindexter, P. Smith, D. Benjamin, 2014, Antimicrobial Agents and Chemotherapy.

Determining Population and Developmental Pharmacokinetics of Metronidazole Using Plasma and Dried Blood Spot Samples From Premature Infants

P. Smith, G. Kearns, M. Sampson, 2013, The Pediatric infectious disease journal.

Population Pharmacokinetics of Piperacillin Using Scavenged Samples From Preterm Infants

M. Walsh, N. Newman, D. Ouellet, 2012, Therapeutic drug monitoring.

Population Pharmacokinetics of Metronidazole Evaluated Using Scavenged Samples from Preterm Infants

M. Walsh, N. Newman, P. Smith, 2012, Antimicrobial Agents and Chemotherapy.

Traumatic Lumbar Punctures in Neonates: Test Performance of the Cerebrospinal Fluid White Blood Cell Count

C. M. Cotten, P. Smith, D. Benjamin, 2008, The Pediatric infectious disease journal.

Morphine vs Methadone Treatment for Infants with Neonatal Abstinence Syndrome

P. Smith, M. Bennett, D. Benjamin, 2018, The Journal of pediatrics.

Role of Flavin-Containing Monooxygenase in Oxidative Metabolism of Voriconazole by Human Liver Microsomes

D. Benjamin, P. Annaert, P. Augustijns, 2008, Drug Metabolism and Disposition.

Calcineurin Controls Growth, Morphology, and Pathogenicity in Aspergillus fumigatus

J. Heitman, J. Perfect, R. A. Cramer, 2006 .

Prolonged Post-Discontinuation Antibiotic Exposure in Very Low Birth Weight Neonates at Risk for Early-Onset Sepsis.

D. Benjamin, M. Cohen-Wolkowiez, K. Zimmerman, 2021, Journal of the Pediatric Infectious Diseases Society.

Drug Dosing and Pharmacokinetics in Children With Obesity: A Systematic Review.

J. Barrett, D. Benjamin, M. Cohen-Wolkowiez, 2015, JAMA pediatrics.

The Use of Supplemental Hydrocortisone in the Management of Persistent Pulmonary Hypertension of the Newborn

R. Goldberg, D. Benjamin, K. Zimmerman, 2021, Journal of Perinatology.

Racial differences are seen in blood pressure response to fosinopril in hypertensive children.

R. Califf, R. Portman, R. Hogg, 2006, American heart journal.

Paradoxical Antibiotic Effect of Ampicillin

P. Smith, A. Tremoulet, D. Benjamin, 2020, The Pediatric infectious disease journal.

Cefazolin Pharmacokinetics in Premature Infants

K. Brouwer, P. Smith, D. Benjamin, 2019, Journal of Perinatology.

Recruitment and Retention in Pediatric Clinical Trials: Focus on Pediatric Research Networks in the US and EU

M. Laughon, D. Benjamin, R. Smyth, 2013 .

Predictors of Prolonged Breast Milk Provision to Very Low Birth Weight Infants

C. M. Cotten, P. Smith, M. Miranda, 2018, The Journal of pediatrics.

Solithromycin Pharmacokinetics in Plasma and Dried Blood Spots and Safety in Adolescents

P. Smith, K. Keedy, D. Benjamin, 2016, Antimicrobial Agents and Chemotherapy.

Epidemiology of respiratory syncytial virus in various regions within North Carolina during multiple seasons.

D. Wilfret, D. Benjamin, E. Palavecino, 2008, North Carolina medical journal.

Quantification of 1,3-β-d-Glucan Levels in Children: Preliminary Data for Diagnostic Use of the β-Glucan Assay in a Pediatric Setting

B. Alexander, P. Smith, D. Benjamin, 2007, Clinical and Vaccine Immunology.

Antifungal treatment in pediatric patients.

D. Benjamin, W. Steinbach, T. Zaoutis, 2005, Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy.

Cefepime and Ceftazidime Safety in Hospitalized Infants

P. Smith, D. Benjamin, C. Hornik, 2015, The Pediatric infectious disease journal.

The pharmacokinetics and pharmacodynamics of micafungin in experimental hematogenous Candida meningoencephalitis: implications for echinocandin therapy in neonates.

G. Drusano, D. Benjamin, T. Walsh, 2008, The Journal of infectious diseases.

Pharmacokinetics of Clindamycin in Obese and Nonobese Children

P. Smith, D. Benjamin, M. Cohen-Wolkowiez, 2017, Antimicrobial Agents and Chemotherapy.

Drug Dosing in Obese Children: A Systematic Review of Current Pharmacokinetic Data

Daniela, J. Barrett, D. Benjamin, 2015 .

Gaps in Drug Dosing for Obese Children: A Systematic Review of Commonly Prescribed Acute Care Medications

D. Benjamin, David Siegel, Stevie Rowe, 2015 .

Safety and effectiveness of meropenem in infants with suspected or complicated intra-abdominal infections.

B. Poindexter, M. Walsh, N. Finer, 2012, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Population Pharmacokinetics of Meropenem in Plasma and Cerebrospinal Fluid of Infants With Suspected or Complicated Intra-abdominal Infections

B. Poindexter, M. Walsh, N. Finer, 2011, The Pediatric infectious disease journal.

Sildenafil Exposure and Hemodynamic Effect After Fontan Surgery

M. Laughon, P. Barker, Jennifer S. Li, 2014, Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies.

Cross-reactive immunologic material status affects treatment outcomes in Pompe disease infants.

H. Mandel, D. Bali, Jennifer S. Li, 2010, Molecular genetics and metabolism.

Higher clearance of micafungin in neonates compared with adults: role of age‐dependent micafungin serum binding

P. Smith, D. Benjamin, P. Annaert, 2011, Biopharmaceutics & drug disposition.

Medication Use in the Neonatal Intensive Care Unit

M. Laughon, P. Smith, D. Benjamin, 2013, American Journal of Perinatology.

Group B Streptococcus and Escherichia coli Infections in the Intensive Care Nursery in the Era of Intrapartum Antibiotic Prophylaxis

M. Laughon, P. Smith, D. Benjamin, 2012, The Pediatric infectious disease journal.

Exposure–Response Analysis of Micafungin in Neonatal Candidiasis

P. Bonate, D. Kaufman, P. Smith, 2018, The Pediatric infectious disease journal.

Venous thrombosis in patients with short- and long-term central venous catheter–associated Staphylococcus aureus bacteremia*

V. Fowler, D. Benjamin, L. Reller, 2008, Critical care medicine.

Criteria supporting the study of drugs in the newborn.

D. Benjamin, R. Ward, W. Rodriguez, 2006, Clinical therapeutics.

Empirical Antibiotic Therapy for Suspected Early-Onset Bacterial Sepsis

B. Stoll, A. Spitzer, C. M. Cotten, 2012, Pediatrics.

Pharmacokinetics and Pharmacodynamics of Antifungals in Children: Clinical Implications

D. Benjamin, M. Cohen-Wolkowiez, E. Capparelli, 2014, Drugs.

The use of antifungal therapy in neonatal intensive care.

P. Smith, D. Benjamin, D. Testoni, 2012, Clinics in perinatology.

Fluconazole Dosing for the Prevention or Treatment of Invasive Candidiasis in Young Infants

D. Kaufman, J. Barrett, P. Adamson, 2009, The Pediatric infectious disease journal.

Candida infective endocarditis

V. Fowler, D. Levine, J. Baddley, 2008, European Journal of Clinical Microbiology & Infectious Diseases.

Clinical Isolates Kingella kingae and Pilus-Associated Phenotypes in Examination of Type IV Pilus Expression

D. Benjamin, T. Kehl-Fie, P. Yagupsky, 2014 .

Examination of Type IV Pilus Expression and Pilus-Associated Phenotypes in Kingella kingae Clinical Isolates

D. Benjamin, J. S. St. Geme, T. Kehl-Fie, 2010, Infection and Immunity.

Commentaries on ‘Antifungal therapy in infants and children with proven, probable or suspected invasive fungal infections’ with a response from the review authors

D. Benjamin, M. Cohen-Wolkowiez, A. Groll, 2010 .

Pediatric exclusivity and other contemporary regulatory changes: impact on pediatric drug study, labeling and safety

P. Smith, Jennifer S. Li, D. Benjamin, 2013 .

Use of Electronic Health Records to Identify Exposure-Response Relationships in Critically Ill Children: An Example of Midazolam and Delirium

F. Boakye-Agyeman, P. Smith, Tracy Spears, 2021, Journal of Pediatric Intensive Care.

In Vitro Analyses, Animal Models, and 60 Clinical Cases of Invasive Aspergillus terreus Infection

J. Perfect, W. Schell, D. Benjamin, 2004, Antimicrobial Agents and Chemotherapy.

A Phase 3 Study of Micafungin Versus Amphotericin B Deoxycholate in Infants With Invasive Candidiasis

D. Kaufman, P. Smith, D. Benjamin, 2018, The Pediatric infectious disease journal.

Anidulafungin for Neonatal Hematogenous Candida Meningoencephalitis: Identification of Candidate Regimens for Humans Using a Translational Pharmacological Approach

D. Benjamin, M. Cohen-Wolkowiez, T. Walsh, 2011, Antimicrobial Agents and Chemotherapy.

Neonatal Candidiasis: Epidemiology, Risk Factors, and Clinical Judgment

B. Poindexter, M. Walsh, B. Stoll, 2010, Pediatrics.

Population Pharmacokinetics of Micafungin in Neonates and Young Infants

P. Smith, D. Benjamin, M. Cohen-Wolkowiez, 2010, Antimicrobial Agents and Chemotherapy.

Neonatal Meningitis: What Is the Correlation Among Cerebrospinal Fluid Cultures, Blood Cultures, and Cerebrospinal Fluid Parameters?

V. Fowler, C. M. Cotten, P. Smith, 2006, Pediatrics.

Population Pharmacokinetics and Safety of Solithromycin following Intravenous and Oral Administration in Infants, Children, and Adolescents

F. Boakye-Agyeman, D. Benjamin, M. Cohen-Wolkowiez, 2018, Antimicrobial Agents and Chemotherapy.

Role of complement receptors 1 and 2 (CD35 and CD21), C3, C4, and C5 in survival by mice of Staphylococcus aureus bacteremia.

D. Benjamin, M. Frank, K. Cunnion, 2004, The Journal of laboratory and clinical medicine.

Wide range of perioperative drugs and doses used in inguinal hernia repairs for premature infants

Kristin M Corey, M. Laughon, D. Benjamin, 2020, Journal of Perinatology.

Early-onset sepsis in term infants admitted to neonatal intensive care units (2011–2016)

P. Smith, D. Benjamin, K. Zimmerman, 2020, Journal of Perinatology.

Early lumbar puncture and risk of intraventricular hemorrhage in very low birth weight infants.

P. Smith, D. Benjamin, C. Hornik, 2018, Early human development.

Neonatal Escherichia coli Bloodstream Infections: Clinical Outcomes and Impact of Initial Antibiotic Therapy

J. Thaden, V. Fowler, P. Smith, 2015, The Pediatric infectious disease journal.

Successful medical treatment of cutaneous aspergillosis in a premature infant using liposomal amphotericin B, voriconazole and micafungin.

A. Mejias, P. Sánchez, H. Jafri, 2007, The Pediatric infectious disease journal.

Hospital-acquired Pneumonia and Ventilator-associated Pneumonia in Children

R. Frenck, P. Smith, Tracy Spears, 2020, The Pediatric infectious disease journal.

Sildenafil Exposure and Hemodynamic Effect After Stage II Single-Ventricle Surgery

M. Laughon, P. Barker, Jennifer S. Li, 2013, Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies.

Triazole use in the nursery: fluconazole, voriconazole, posaconazole, and ravuconazole.

D. Benjamin, M. Cohen-Wolkowiez, K. Watt, 2013, Current drug metabolism.

External Evaluation of Two Fluconazole Infant Population Pharmacokinetic Models

K. Kennedy, S. Duara, P. Smith, 2017, Antimicrobial Agents and Chemotherapy.

The management of Candida infections in preterm neonates and the role of micafungin

D. Benjamin, W. Hope, E. Castagnola, 2011, The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians.

Use and Safety of Erythromycin and Metoclopramide in Hospitalized Infants

P. Smith, D. Benjamin, C. Hornik, 2015, Journal of pediatric gastroenterology and nutrition.

Medication Use in the Neonatal Intensive Care Unit and Changes from 2010-2018.

M. Laughon, P. Smith, D. Benjamin, 2021, The Journal of pediatrics.

Pharmacokinetic studies in infants using minimal-risk study designs.

P. Smith, M. Sampson, D. Benjamin, 2014, Current clinical pharmacology.

Association between thrombosis and bloodstream infection in neonates with peripherally inserted catheters.

C. M. Cotten, P. Smith, C. Thornburg, 2008, Thrombosis research.

Effect of fluconazole prophylaxis on Candida fluconazole susceptibility in premature infants

Robert D. White, B. Poindexter, D. Kaufman, 2018, The Journal of antimicrobial chemotherapy.

Mortality Risk Factors Among Infants Receiving Dialysis in the Neonatal Intensive Care Unit

Marcella H. Boynton, M. Laughon, D. Benjamin, 2021, The Journal of Pediatrics.

Antifungal agents and therapy for infants and children with invasive fungal infections: a pharmacological perspective

P. Smith, D. Benjamin, M. Cohen-Wolkowiez, 2013, British journal of clinical pharmacology.

Pediatric Cardiovascular Drug Dosing in Critically Ill Children and Extracorporeal Membrane Oxygenation

Jennifer S. Li, D. Benjamin, M. Cohen-Wolkowiez, 2011, Journal of cardiovascular pharmacology.

Treatment and prophylaxis of invasive candidiasis.

D. Benjamin, K. Watt, N. Tripathi, 2012, Seminars in perinatology.

Pharmacokinetics and Safety of Fluconazole in Young Infants Supported With Extracorporeal Membrane Oxygenation

K. Brouwer, P. Smith, D. Benjamin, 2012, The Pediatric infectious disease journal.

Innovative clinical trial design for pediatric therapeutics

M. Laughon, J. Barrett, G. Kearns, 2011, Expert review of clinical pharmacology.

Pharmacokinetics and Safety of Micafungin in Infants Supported With Extracorporeal Membrane Oxygenation

K. Brouwer, D. Benjamin, M. Cohen-Wolkowiez, 2016, The Pediatric infectious disease journal.

Fluconazole Population Pharmacokinetics and Dosing for Prevention and Treatment of Invasive Candidiasis in Children Supported with Extracorporeal Membrane Oxygenation

K. Brouwer, J. Barrett, D. Benjamin, 2015, Antimicrobial Agents and Chemotherapy.

Fluconazole Loading Dose Pharmacokinetics and Safety in Infants

P. Smith, J. Barrett, D. Benjamin, 2011, The Pediatric infectious disease journal.

Pharmacokinetics of an Elevated Dosage of Micafungin in Premature Neonates

D. Kaufman, P. Smith, G. Kearns, 2009, The Pediatric infectious disease journal.

Editorial commentary: Fluconazole therapeutic drug monitoring in children with cancer: not today.

D. Benjamin, M. Cohen-Wolkowiez, 2014, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Clinical practice guidelines for the management of candidiasis: 2009 update by the Infectious Diseases Society of America.

J. Sobel, T. Calandra, D. Benjamin, 2009, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Rifampin Pharmacokinetics and Safety in Preterm and Term Infants

B. Poindexter, F. Boakye-Agyeman, C. M. Cotten, 2019, Antimicrobial Agents and Chemotherapy.

Clindamycin Pharmacokinetics and Safety in Preterm and Term Infants

B. Poindexter, C. M. Cotten, M. Laughon, 2016, Antimicrobial Agents and Chemotherapy.

Pharmacokinetics of ticarcillin–clavulanate in premature infants

Stephen J. Balevic, C. M. Cotten, M. Laughon, 2019, British journal of clinical pharmacology.

Pharmacoepidemiology of Furosemide in the Neonatal Intensive Care Unit.

Karan R. Kumar, M. Laughon, P. Smith, 2020, Neonatology.

Safety and Pharmacokinetics of Intravenous Anidulafungin in Children with Neutropenia at High Risk for Invasive Fungal Infections

D. Benjamin, T. Walsh, N. Seibel, 2006, Antimicrobial Agents and Chemotherapy.

In Vitro Hepatic Metabolism Explains Higher Clearance of Voriconazole in Children versus Adults: Role of CYP2C19 and Flavin-Containing Monooxygenase 3

J. Ibrahim, D. Benjamin, P. Annaert, 2010, Drug Metabolism and Disposition.

Therapeutic Monitoring of Voriconazole in Children Less Than Three Years of Age: A Case Report and Summary of Voriconazole Concentrations for Ten Children

D. Benjamin, M. Cohen-Wolkowiez, A. Blaschke, 2012, The Pediatric infectious disease journal.

Safety, Effectiveness and Exposure-response of Micafungin in Infants: Application of an Established Pharmacokinetics Model to Electronic Health Records

P. Smith, D. Benjamin, M. Cohen-Wolkowiez, 2019, The Pediatric infectious disease journal.

Population Pharmacokinetics of Micafungin and Its Metabolites M1 and M5 in Children and Adolescents

D. Benjamin, W. Hope, A. Arrieta, 2014, Antimicrobial Agents and Chemotherapy.

Physiologically‐Based Pharmacokinetic Modeling of Fluconazole Using Plasma and Cerebrospinal Fluid Samples From Preterm and Term Infants

S. Duara, P. Smith, G. Kearns, 2019, CPT: pharmacometrics & systems pharmacology.

Population Pharmacokinetics of Fluconazole in Young Infants

D. Kaufman, J. Barrett, P. Adamson, 2008, Antimicrobial Agents and Chemotherapy.

Commentary: pediatric antifungal drug development: lessons learned and recommendations for the future.

D. Benjamin, M. Cohen-Wolkowiez, R. Ward, 2012, The Pediatric Infectious Disease Journal.

Effect of renal function on antihypertensive drug safety and efficacy in children

P. Smith, Jennifer S. Li, D. Benjamin, 2017, Pediatric Nephrology.

Simulated Assessment of Pharmacokinetically Guided Dosing for Investigational Treatments of Pediatric Patients With Coronavirus Disease 2019.

Stephen J. Balevic, P. Smith, D. Benjamin, 2020, JAMA pediatrics.

Association of Atrial Septal Defects and Bronchopulmonary Dysplasia in Premature Infants

Karan R. Kumar, M. Laughon, P. Smith, 2018, The Journal of pediatrics.

Sports Medicine and Ethics

P. Smith, D. Benjamin, Ross E McKinney, 2013, The American journal of bioethics : AJOB.

New antifungal agents under development in children and neonates

D. Benjamin, W. Steinbach, 2005, Current opinion in infectious diseases.

Advances in the treatment of invasive neonatal candidiasis

D. Benjamin, M. Cohen-Wolkowiez, Lorena Botero-Calderon, 2015, Expert opinion on pharmacotherapy.

Safety of High-dose Acyclovir in Infants With Suspected and Confirmed Neonatal Herpes Simplex Virus Infections

P. Smith, D. Benjamin, C. Hornik, 2017, The Pediatric infectious disease journal.

Amphotericin B Penetrates into the Central Nervous System through Focal Disruption of the Blood-Brain Barrier in Experimental Hematogenous Candida Meningoencephalitis

B. Klaunberg, M. Lizak, D. Benjamin, 2019, Antimicrobial Agents and Chemotherapy.

Infants: Yeasts are beasts in early life

D. Benjamin, R. Greenberg, 2009, Antifungal Therapy.

Population Pharmacokinetics of Fluconazole in Premature Infants with Birth Weights Less than 750 Grams

G. Natarajan, M. Laughon, P. Smith, 2016, Antimicrobial Agents and Chemotherapy.

Management of Neonatal Candidiasis

P. Smith, D. Benjamin, M. Cohen-Wolkowiez, 2011 .

Treatment of neonatal fungal infections.

D. Benjamin, C. Moran, 2010, Advances in experimental medicine and biology.

Invasive Candida infections in the neonate.

D. Benjamin, W. Steinbach, P. Brian Smith, 2005, Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy.

Old and new: appropriate dosing for neonatal antifungal drugs in the nursery.

D. Benjamin, J. Ericson, P. Manzoni, 2013, Early human development.

Antifungal Therapy and Outcomes in Infants With Invasive Candida Infections

P. Smith, D. Benjamin, M. Cohen-Wolkowiez, 2012, The Pediatric infectious disease journal.

Nosocomial Infection in the NICU: A Medical Complication or Unavoidable Problem?

Robert D. White, P. Sánchez, D. Benjamin, 2004, Journal of Perinatology.

Neurodevelopmental outcome of extremely low birth weight infants with Candida infection.

M. Walsh, B. Vohr, R. Ehrenkranz, 2013, The Journal of pediatrics.

Neonatal Candidiasis Among Extremely Low Birth Weight Infants: Risk Factors, Mortality Rates, and Neurodevelopmental Outcomes at 18 to 22 Months

William Oh, Daniel K. Benjamin, Barbara J. Stoll, 2006, Pediatrics.

Pharmacokinetics of antifungal agents in children.

D. Benjamin, M. Cohen-Wolkowiez, K. Watt, 2011, Early human development.

Comparative safety of amphotericin B lipid complex and amphotericin B deoxycholate as aerosolized antifungal prophylaxis in lung-transplant recipients

J. Perfect, D. Benjamin, S. Palmer, 2004, Transplantation.

When to Suspect Fungal Infection in Neonates: A Clinical Comparison of Candida albicans and Candida parapsilosis Fungemia With Coagulase-Negative Staphylococcal Bacteremia

R. Auten, D. Benjamin, R. McKinney, 2000, Pediatrics.

Candida virulence properties and adverse clinical outcomes in neonatal candidiasis.

B. Stoll, S. Shankaran, R. Higgins, 2012, The Journal of pediatrics.

Zygomycosis in neonates: an uncommon but life-threatening infection.

D. Benjamin, T. Walsh, T. Zaoutis, 2009, American journal of perinatology.

Fluconazole prophylaxis for prevention of invasive candidiasis in infants

D. Benjamin, J. Ericson, 2014, Current opinion in pediatrics.

Outcomes following candiduria in extremely low birth weight infants.

M. Walsh, B. Stoll, S. Shankaran, 2012, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Cryptococcus neoformans α Strains Preferentially Disseminate to the Central Nervous System during Coinfection

T. G. Mitchell, J. Heitman, A. Casadevall, 2005, Infection and Immunity.

Role of echinocandins in the management of fungal infections in neonates

M. Mostert, D. Benjamin, P. Manzoni, 2010, The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians.

For Peer Review Higher clearance of micafungin in neonates compared to adults: role of age-dependent micafungin serum binding

D. Benjamin, P. Annaert, P. Augustijns, 2011 .

Pharmacological resolution of a multiloculated Candida spp. liver abscess in a preterm neonate.

M. Mostert, D. Benjamin, P. Paolillo, 2013, Early human development.

Prevention and Treatment of Nosocomial Sepsis in the NICU

Robert D. White, P. Sánchez, D. Benjamin, 2004, Journal of Perinatology.

Very late onset infections in the neonatal intensive care unit.

P. Smith, D. Benjamin, M. Cohen-Wolkowiez, 2012, Early human development.

Mortality Following Blood Culture in Premature Infants: Increased with Gram-negative Bacteremia and Candidemia, but Not Gram-positive Bacteremia

Reese H Clark, D. Benjamin, W. Steinbach, 2004, Journal of Perinatology.

Calcineurin Controls Growth, Morphology, and Pathogenicity in Aspergillus fumigatus

William R. Kirkpatrick, Joseph Heitman, Daniel K. Benjamin, 2006, Eukaryotic Cell.

Quantification of 1,3-beta-D-glucan levels in children: preliminary data for diagnostic use of the beta-glucan assay in a pediatric setting.

B. Alexander, P. Smith, D. Benjamin, 2007, Clinical and vaccine immunology : CVI.

Changes in the Incidence of Candidiasis in Neonatal Intensive Care Units

D. Kaufman, M. Laughon, P. Smith, 2014, Pediatrics.

Effect of fluconazole prophylaxis on candidiasis and mortality in premature infants: a randomized clinical trial.

Robert D. White, D. Kaufman, G. Natarajan, 2014, JAMA.

Risk Factors for Invasive Candidiasis in Infants >1500 g Birth Weight

A. Herring, P. Smith, D. Benjamin, 2012, The Pediatric infectious disease journal.

Evaluation of Gentamicin Exposure in the Neonatal Intensive Care Unit and Hearing Function at Discharge

D. Benjamin, D. Gonzalez, C. Hornik, 2018, The Journal of pediatrics.

Exposure-response Relationships of Metronidazole in Infants: Integration of Electronic Health Record Data With Population Pharmacokinetic Modeling-derived Exposure Simulation

D. Benjamin, C. Hornik, R. Clark, 2022, The Pediatric infectious disease journal.

Rifampin Use and Safety in Hospitalized Infants

P. Smith, D. Benjamin, C. Hornik, 2015, American Journal of Perinatology.

Survival Benefit of Empirical Therapy for Staphylococcus aureus Bloodstream Infections in Infants

J. Thaden, V. Fowler, P. Smith, 2015, The Pediatric infectious disease journal.

Late-onset Bloodstream Infections in Hospitalized Term Infants

P. Smith, D. Benjamin, M. Cohen-Wolkowiez, 2014, The Pediatric infectious disease journal.

Early and Late Onset Sepsis in Late Preterm Infants

C Michael Cotten, Reese H. Clark, Daniel K. Benjamin, 2009, The Pediatric infectious disease journal.

Fluconazole Prophylaxis for the Prevention of Candidiasis in Premature Infants: A Meta-analysis Using Patient-level Data.

B. Poindexter, D. Kaufman, S. Shankaran, 2016, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

School Safety, Masking, and the Delta Variant.

D. Benjamin, K. Zimmerman, Angelique E. Boutzoukas, 2021, Pediatrics.

Burden of Invasive Staphylococcus aureus Infections in Hospitalized Infants.

V. Fowler, P. Smith, D. Benjamin, 2015, JAMA pediatrics.

Meningitis in preterm neonates: importance of cerebrospinal fluid parameters.

P. Smith, D. Benjamin, T. Walsh, 2008, American journal of perinatology.

No Survival Benefit With Empirical Vancomycin Therapy for Coagulase-negative Staphylococcal Bloodstream Infections in Infants

J. Thaden, V. Fowler, P. Smith, 2015, The Pediatric infectious disease journal.

Use of the Complete Blood Cell Count in Early-onset Neonatal Sepsis

P. Smith, Jennifer S. Li, D. Benjamin, 2012, The Pediatric infectious disease journal.

Ampicillin Dosing in Premature Infants for Early-onset Sepsis: Exposure-driven Efficacy, Safety, and Stewardship

D. Benjamin, M. Cohen-Wolkowiez, K. Zimmerman, 2022, Journal of Perinatology.

Timing of Multiorgan Dysfunction among Hospitalized Infants with Fatal Fulminant Sepsis

P. Smith, D. Benjamin, M. Kelly, 2016, American Journal of Perinatology.

Predictors of Positive Cerebrospinal Fluid Cultures in Infants With Bacteremia

M. Laughon, P. Smith, D. Benjamin, 2014, The Pediatric Infectious Disease Journal.

Effectiveness of Granulocyte Colony-Stimulating Factor in Hospitalized Infants with Neutropenia

P. Smith, D. Benjamin, Jin A. Lee, 2016, American Journal of Perinatology.

Group B streptococcal meningitis: cerebrospinal fluid parameters in the era of intrapartum antibiotic prophylaxis.

P. Smith, Jennifer S. Li, D. Benjamin, 2009, Early human development.

Early sepsis does not increase the risk of late sepsis in very low birth weight neonates.

Abhik Das, B. Stoll, W. Carlo, 2013, The Journal of pediatrics.

Critical Appraisal of the Role of Ureaplasma in the Development of Bronchopulmonary Dysplasia With Metaanalytic Techniques

R. Schelonka, D. Benjamin, K. Waites, 2005, The Pediatric infectious disease journal.

Safety of Enalapril in Infants Admitted to the Neonatal Intensive Care Unit

P. Smith, D. Benjamin, K. Zimmerman, 2016, Pediatric Cardiology.

Safety of histamine-2 receptor blockers in hospitalized VLBW infants.

P. Smith, D. Benjamin, C. Hornik, 2016, Early human development.

The Association of Third-Generation Cephalosporin Use and Invasive Candidiasis in Extremely Low Birth-Weight Infants

B. Stoll, R. Goldberg, K. Poole, 2006, Pediatrics.

Early Caffeine Prophylaxis and Risk of Failure of Initial Continuous Positive Airway Pressure in Very Low Birth Weight Infants

D. Carlton, D. Benjamin, K. Zimmerman, 2017, The Journal of pediatrics.

Outcomes associated with surfactant in more mature and larger premature infants with respiratory distress syndrome

M. Laughon, D. Benjamin, N. Bamat, 2020, Journal of Perinatology.

Anaerobic Antimicrobial Therapy After Necrotizing Enterocolitis in VLBW Infants

M. Laughon, P. Smith, D. Benjamin, 2015, Pediatrics.

Postconception Age and Other Risk Factors Associated with Mortality Following Gram-negative Rod Bacteremia

D. Benjamin, R. Clark, H. Garges, 2004, Journal of Perinatology.

Population Pharmacokinetics and Exploratory Exposure‐Response Relationships of Diazepam in Children Treated for Status Epilepticus

J. Chamberlain, G. Kearns, D. Benjamin, 2018, CPT: pharmacometrics & systems pharmacology.

Postnatal Cytomegalovirus Infection and the Risk for Bronchopulmonary Dysplasia.

M. Laughon, P. Smith, D. Benjamin, 2015, JAMA pediatrics.

Funding Pediatric Subspecialty Training: Are T32 Grants the Future?

D. Benjamin, W. Steinbach, J. Sleasman, 2018, Jornal de Pediatria.

Pediatric residents' clinical diagnostic accuracy of otitis media.

T. Sectish, A. Messner, D. Benjamin, 2002, Pediatrics.

Safety and Pharmacokinetic Profiles of Repeated-dose Micafungin in Children and Adolescents Treated for Invasive Candidiasis

D. Benjamin, A. Arrieta, J. Deville, 2013, The Pediatric infectious disease journal.

Predictive value of cerebrospinal fluid parameters in neonates with intraventricular drainage devices.

P. Smith, D. Benjamin, P. Seed, 2007, Journal of neurosurgery.

Association between Nephrotoxic Drug Combinations and Acute Kidney Injury in the Neonatal Intensive Care Unit.

M. Laughon, D. Benjamin, D. Gonzalez, 2020, The Journal of pediatrics.

Development and Evaluation of a Virtual Population of Children with Obesity for Physiologically Based Pharmacokinetic Modeling

Karan R. Kumar, M. Laughon, G. Kearns, 2021, Clinical Pharmacokinetics.

Is pediatric exclusivity working

R. Califf, P. Smith, Jennifer S. Li, 2007 .

Prevalence and safety of diazoxide in the neonatal intensive care unit

D. Benjamin, R. Clark, R. Greenberg, 2018, Journal of Perinatology.

Prolonged furosemide exposure and risk of abnormal newborn hearing screen in premature infants.

R. Goldberg, M. Laughon, P. Smith, 2018, Early Human Development.

Immunotherapy in neonatal sepsis: advances in treatment and prophylaxis

D. Benjamin, M. Cohen-Wolkowiez, E. Capparelli, 2009, Current opinion in pediatrics.

93 – Clinical Approach to the Infected Neonate

P. Smith, D. Benjamin, 2012 .

Outcomes of Catheter-associated Infections in Pediatric Patients With Short Bowel Syndrome

P. Smith, D. Benjamin, M. Cohen-Wolkowiez, 2010, Journal of pediatric gastroenterology and nutrition.

Probiotic Use and Safety in the Neonatal Intensive Care Unit: A Matched Cohort Study.

D. Benjamin, J. Messina, K. Zimmerman, 2020, The Journal of pediatrics.

Incidence of Breakthrough Urinary Tract Infection in Hospitalized Infants Receiving Antibiotic Prophylaxis

P. Smith, D. Benjamin, C. Hornik, 2017, Clinical pediatrics.

Adverse Events Associated With Meropenem Versus Imipenem/Cilastatin Therapy in a Large Retrospective Cohort of Hospitalized Infants

A. Herring, P. Smith, G. Kearns, 2013, The Pediatric infectious disease journal.

Association between neonatal intensive care unit medication safety practices, adverse events, and death

C. Bose, P. Smith, D. Benjamin, 2020, Journal of Perinatology.

Pharmacokinetics of Moxifloxacin in an Infant With Mycoplasma hominis Meningitis

M. Laughon, D. Benjamin, M. Cohen-Wolkowiez, 2012, The Pediatric infectious disease journal.

Metronidazole Metabolism in Neonates and the Interplay Between Ontogeny and Genetic Variation

R. Tyndale, G. Kearns, D. Benjamin, 2017, Journal of clinical pharmacology.

Improved Neurodevelopmental Outcomes following Long-Term High-Dose Oral Acyclovir Therapy in Infants with Central Nervous System and Disseminated Herpes Simplex Disease

D. Benjamin, D. Benjamin, P. Palasanthiran, 2005, Journal of Perinatology.

Solithromycin in Children and Adolescents With Community-acquired Bacterial Pneumonia

D. Benjamin, M. Cohen-Wolkowiez, J. Lang, 2022, The Pediatric infectious disease journal.

Safety Monitoring of Drugs Receiving Pediatric Marketing Exclusivity

R. Califf, P. Smith, Jennifer S. Li, 2008, Pediatrics.

Antibiotic Safety and Effectiveness in Premature Infants With Complicated Intraabdominal Infections

Jinson J. Erinjeri, P. Smith, D. Benjamin, 2021, The Pediatric infectious disease journal.

Risk factors for Group B streptococcal disease in neonates of mothers with negative antenatal testing

P. Smith, D. Benjamin, J. Messina, 2016, Journal of Perinatology.

Risk factors and prevention of late-onset sepsis in premature infants.

P. Smith, D. Benjamin, L. C. Downey, 2010, Early human development.

Sedation, Analgesia, and Paralysis during Mechanical Ventilation of Premature Infants

T. Stürmer, M. Laughon, D. Benjamin, 2017, The Journal of pediatrics.

Is an Increased Dwell Time of a Peripherally Inserted Catheter Associated With an Increased Risk of Bloodstream Infection in Infants?

P. Smith, C. Thornburg, D. Benjamin, 2008, Infection Control & Hospital Epidemiology.

Pharmacokinetics and Tolerability of Single-Dose Daptomycin in Young Infants

P. Smith, D. Benjamin, M. Cohen-Wolkowiez, 2012, The Pediatric infectious disease journal.

Recent Advances in the Detection of Neonatal Candidiasis

P. Smith, D. Benjamin, M. Cohen-Wolkowiez, 2010, Current fungal infection reports.

Coagulase-Negative Staphylococcal Infections in the Neonatal Intensive Care Unit

V. Fowler, M. Laughon, P. Smith, 2011, Infection Control & Hospital Epidemiology.

Candidiasis in Extremely Low Birth-Weight Infants The Association of Third-Generation Cephalosporin Use and Invasive

B. Stoll, R. Goldberg, D. Benjamin, 2013 .

Clinical characteristics and response to prophylactic fluconazole of preterm VLBW neonates with baseline and acquired fungal colonisation in NICU: data from a multicentre RCT.

F. Mosca, M. Mostert, D. Benjamin, 2012, Early human development.

Use of the Complete Blood Cell Count in Late-onset Neonatal Sepsis

P. Smith, Jennifer S. Li, D. Benjamin, 2012, The Pediatric infectious disease journal.

Medications and in-hospital outcomes in infants born at 22–24 weeks of gestation

D. Benjamin, A. Wilson, N. Younge, 2020, Journal of Perinatology.

Furosemide Exposure and Prevention of Bronchopulmonary Dysplasia in Premature Infants

M. Laughon, P. Smith, D. Benjamin, 2019, The Journal of pediatrics.

Very low birth weight neonates who survive early-onset sepsis do not have an increased risk of developing late-onset sepsis.

P. Smith, D. Benjamin, C. Hornik, 2012, Early human development.

In Vitro Interactions between Antifungals and Immunosuppressants against Aspergillus fumigatus Isolates from Transplant and Nontransplant Patients

Joseph Heitman, Daniel K. Benjamin, Nina Singh, 2004, Antimicrobial Agents and Chemotherapy.

Globalization of Pediatric Research: Analysis of Clinical Trials Completed for Pediatric Exclusivity

P. Smith, Jennifer S. Li, D. Benjamin, 2010, Pediatrics.

Vancomycin Cerebrospinal Fluid Pharmacokinetics in Children with Cerebral Ventricular Shunt Infections

P. Smith, G. Grant, D. Benjamin, 2014, The Pediatric infectious disease journal.

Effect of Methicillin-Resistant Staphylococcus aureus Colonization in the Neonatal Intensive Care Unit on Total Hospital Cost

R. Goldberg, P. Smith, D. Benjamin, 2009, Infection Control & Hospital Epidemiology.

Objective: Determine sildenafil exposure and hemodynamic effect in children after Fontan single-ventricle surgery. Design: Prospective dose-escalation trial. Setting: Single-center pediatric catheterization laboratory. Patients: Nine children post Fontan single-ventricle surgical pal- liation and un

M. Laughon, P. Barker, Jennifer S. Li, 2013 .

Empiric antifungal therapy and outcomes in extremely low birth weight infants with invasive candidiasis.

B. Poindexter, M. Walsh, R. Ehrenkranz, 2012, The Journal of pediatrics.

Staphylococcus aureus bacteremia among patients with health care-associated fever.

V. Fowler, D. Benjamin, L. Reller, 2009, The American journal of medicine.

Safety of Metronidazole in Late Pre-term and Term Infants with Complicated Intra-abdominal Infections

Jinson J. Erinjeri, P. Smith, D. Benjamin, 2020, The Pediatric infectious disease journal.

Comparative Analysis of Ampicillin Plasma and Dried Blood Spot Pharmacokinetics in Neonates

B. Poindexter, F. Boakye-Agyeman, M. Laughon, 2017, Therapeutic drug monitoring.

Cytokine Profiles of Preterm Neonates with Fungal and Bacterial Sepsis

J. Tyson, R. Ehrenkranz, B. Stoll, 2012, Pediatric Research.

Respiratory Support for Very Low Birth Weight Infants Receiving Dexamethasone

M. Laughon, D. Benjamin, C. Hornik, 2017, The Journal of pediatrics.

Excess Costs of Hospital Care Associated With Neonatal Candidemia

P. Smith, S. Fridkin, L. Harrison, 2007, The Pediatric infectious disease journal.

Effect of Fluconazole Prophylaxis on Candidiasis andMortality in Premature Infants

Robert D. White, D. Kaufman, G. Natarajan, 2014 .

Choosing the right empirical antibiotics for neonates

P. Smith, D. Benjamin, 2010, Archives of Disease in Childhood: Fetal and Neonatal Edition.

Safety of sildenafil in premature infants at risk of bronchopulmonary dysplasia: Rationale and methods of a phase II randomized trial

M. Laughon, P. Smith, D. Benjamin, 2022, Contemporary Clinical Trials Communications.

Abatacept, Cenicriviroc, or Infliximab for Treatment of Adults Hospitalized With COVID-19 Pneumonia: A Randomized Clinical Trial.

Cameron K. Murray, Glenda F. Brown, Patrick B. Dorr, 2023, JAMA.

Early Predictors of In-Hospital Death in Infective Endocarditis

Vance G. Fowler, Andrew Wang, V. Fowler, 2004, Circulation.

A meta-analysis of medical versus surgical therapy for Candida endocarditis.

A. Zaas, J. Perfect, V. Fowler, 2005, The Journal of infection.

Non-HACEK Gram-Negative Bacillus Endocarditis

Pierre Tattevin, Francisco Nacinovich, John Klein, 2007, Annals of Internal Medicine.

Trends in COVID-19 diagnoses and outcomes in infants hospitalized in the neonatal intensive care unit.

Courtney K. Blackwell, P. Smith, D. Benjamin, 2023, Journal of Perinatology.

Use of vasopressors for septic shock in the neonatal intensive care unit.

D. Benjamin, C. Hornik, R. Clark, 2023, Journal of perinatology : official journal of the California Perinatal Association.

Impact of Gastrostomy Tube Placement on Short-Term Weight Gain in Hospitalized Premature Infants.

P. Smith, D. Benjamin, K. Zimmerman, 2019, JPEN - Journal of Parenteral and Enteral Nutrition.

Safety Monitoring of Drugs Receiving Pediatric Marketing Exclusivity

R. Califf, P. Smith, Jennifer S. Li, 2008, Pediatrics.

Pharmacokinetics of an Elevated Dosage of Micafungin in Premature Neonates

D. Kaufman, P. Smith, G. Kearns, 2009, The Pediatric infectious disease journal.

Results From a Prospective, International, Epidemiologic Study of Invasive Candidiasis in Children and Neonates

D. Benjamin, T. Walsh, A. Velegraki, 2012, The Pediatric infectious disease journal.

Commentary: pediatric antifungal drug development: lessons learned and recommendations for the future.

D. Benjamin, M. Cohen-Wolkowiez, R. Ward, 2012, The Pediatric infectious disease journal.

Principles of Antifungal Therapy

D. Benjamin, M. Cohen-Wolkowiez, W. Steinbach, 2011 .

Epidemiology of respiratory syncytial virus in various regions within North Carolina during multiple seasons.

D. Wilfret, D. Benjamin, E. Palavecino, 2008, North Carolina medical journal.

Prevalence of Renal Anomalies Following Urinary Tract Infections in Hospitalized Infants Less Than Two Months of Age

B. Alexander, P. Smith, D. Benjamin, 2009, Journal of Perinatology.

Sepsis in young infants with congenital heart disease.

P. Smith, D. Benjamin, Jennifer S. Li, 2012, Early human development.

Early antibiotic exposure in very-low birth weight infants and infection risk at 3–7 days after birth

M. Laughon, D. Benjamin, R. Clark, 2023, Journal of Perinatology.

In Reply

P. Smith, Jennifer S. Li, D. Benjamin, 2011, Pediatrics.