Shane Lofgren

发表

Integrated molecular, clinical, and ontological analysis identifies overlooked disease relationships

N. Shah, Francesco Vallania, P. Khatri, 2018 .

Integrated molecular and clinical analysis for understanding human disease relationships

N. Shah, Francesco Vallania, P. Khatri, 2017, bioRxiv.

Combined inhibition of BET family proteins and histone deacetylases as a potential epigenetics-based therapy for pancreatic ductal adenocarcinoma

Francisco J. Sánchez-Rivera, R. Braren, P. Khatri, 2015, Nature Medicine.

Structure-Based Prediction of Transcription Factor Binding Sites

Jun-tao Guo, Shane Lofgren, Alvin Farrel, 2014 .

Antigen Identification for Orphan T Cell Receptors Expressed on Tumor-Infiltrating Lymphocytes

Purvesh Khatri, David Baltimore, Mark M. Davis, 2017, Cell.

High-throughput quantitative histology in systemic sclerosis skin disease using computer vision

P. Khatri, Shane Lofgren, M. Hinchcliff, 2020, Arthritis Research & Therapy.

Abstract A44: Coordination of stress signals by the lysine methyltransferase SMYD2 promotes pancreatic cancer

P. Khatri, P. Hainaut, J. Sage, 2016 .

CD47-blocking immunotherapies stimulate macrophage-mediated destruction of small-cell lung cancer.

I. Weissman, M. van de Rijn, C. Rudin, 2016, The Journal of clinical investigation.

Leveraging heterogeneity across multiple datasets increases cell-mixture deconvolution accuracy and reduces biological and technical biases

Francesco Vallania, Purvesh Khatri, Andrew Tam, 2018, Nature Communications.

Elevated NSD3 histone methylation activity drives squamous cell lung cancer

J. Minna, I. Wistuba, P. Mazur, 2021, Nature.

Elevated NSD3 Histone Methylation Activity Drives Squamous Cell Lung Cancer

J. Minna, J. Roth, I. Wistuba, 2021, Nature.

METTL13 Methylation of eEF1A Increases Translational Output to Promote Tumorigenesis

Joshua E. Elias, Capucine Van Rechem, A. Maitra, 2019, Cell.

SETD5-Coordinated Chromatin Reprogramming Regulates Adaptive Resistance to Targeted Pancreatic Cancer Therapy.

Matthew J. Meiners, Joshua E. Elias, A. Maitra, 2020, Cancer cell.

Empowering Multi-Cohort Gene Expression Analysis to Increase Reproducibility

Winston Haynes, Francesco Vallania, Purvesh Khatri, 2016, bioRxiv.

Interpretation of biological experiments changes with evolution of the Gene Ontology and its annotations

Dominique T. Alessi, N. Shah, Francesco Vallania, 2018, Scientific Reports.

Interpretation of biological experiments changes with evolution of the Gene Ontology and its annotations

Mark A. Musen, Winston Haynes, Francesco Vallania, 2017, Scientific Reports.

Leveraging heterogeneity across multiple data sets increases accuracy of cell-mixture deconvolution and reduces biological and technical biases

Francesco Vallania, Purvesh Khatri, Andrew Tam, 2017, bioRxiv.

Integrated, multicohort analysis of systemic sclerosis identifies robust transcriptional signature of disease severity.

Alex Kuo, Purvesh Khatri, Shane Lofgren, 2016, JCI insight.

Synthetic promoters capable of driving robust nuclear gene expression in the green alga Chlamydomonas reinhardtii

Andreas Dräger, Stephen P. Mayfield, David L. Masica, 2016 .

Gene Expression Analysis to Assess the Relevance of Rodent Models to Human Lung Injury

Purvesh Khatri, Shane Lofgren, Timothy E Sweeney, 2017, American journal of respiratory cell and molecular biology.

Multiplexed transcriptomic profiling of the fate of human CAR T cells in vivo via genetic barcoding with shielded small nucleotides

P. Mazur, Shane Lofgren, Xiaoyin Lu, 2023, Nature Biomedical Engineering.

Leveraging heterogeneity across multiple datasets increases cell-mixture deconvolution accuracy and reduces biological and technical biases

Mark M. Davis, Michael N. Alonso, Francesco Vallania, 2018, Nature Communications.