A. Alfirevic

N. Beeching, R. Kolamunnage-Dona, M. Pirmohamed, 2014, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Systematic review of preterm birth multi-omic biomarker studies

A. Alfirevic, J. K. Gupta, 2022, Expert Reviews in Molecular Medicine.

Students’ Career Aspirations towards Entrepreneurial and Managerial Jobs: A Comparative Study in Bosnia and Herzegovina, Croatia and Serbia

A. Alfirevic, Saša Petković, Maja Ivanović Đukić, 2018, ACTA ECONOMICA.

Evaluation of agreement of placental growth factor (PlGF) tests and the soluble FMS-like tyrosine kinase 1 (sFlt-1)/PlGF ratio, comparison of predictive accuracy for pre-eclampsia, and relation to uterine artery Doppler and response to aspirin

Z. Alfirevic, A. Alfirevic, A. Jorgensen, 2019, The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians.

Carbamazepine Hypersensitivity: Progress Toward Predicting the Unpredictable

Michael R. Johnson, P. Deloukas, S. Sisodiya, 2011 .

The generation of HepG2 transmitochondrial cybrids to reveal the role of mitochondrial genotype in idiosyncratic drug-induced liver injury

Amy E. Chadwick, A. Alfirevic, Jon Lyon, 2022, bioRxiv.

Response to “HLA Allelic Variants and Carbamazepine‐Induced Hypersensitivity”

M. Pirmohamed, A. Alfirevic, V. Yip, 2013, Clinical pharmacology and therapeutics.

Vaginal bacterial load in the second trimester is associated with early preterm birth recurrence: a nested case–control study

J. H. van de Wijgert, A. Darby, D. Roberts, 2021, medRxiv.

HLA‐DQ allele‐restricted activation of nitroso sulfamethoxazole‐specific CD4‐positive T lymphocytes from patients with cystic fibrosis

M. Pirmohamed, A. Sette, B. K. Park, 2015, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Clozapine-induced agranulocytosis is associated with rare HLA-DQB1 and HLA-B alleles

M. Daly, D. Rujescu, K. Shianna, 2014, Nature Communications.

Metabolic profiling of maternal serum of women at high-risk of spontaneous preterm birth using NMR and MGWAS approach

B. Müller-Myhsok, Z. Alfirevic, A. Alfirevic, 2021, Bioscience reports.

HLA-allelotype associations with nevirapine-induced hypersensitivity reactions and hepatotoxicity: a systematic review of the literature and meta-analysis

M. Pirmohamed, D. Carr, A. Alfirevic, 2015, Pharmacogenetics and genomics.

Genome-wide association study of nevirapine hypersensitivity in a sub-Saharan African HIV-infected population

P. Deloukas, A. Morris, M. Nelson, 2017, The Journal of antimicrobial chemotherapy.

Association of Human Leukocyte Antigen Alleles and Nevirapine Hypersensitivity in a Malawian HIV-Infected Population

M. Pirmohamed, S. Khoo, R. Heyderman, 2013, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Metabolic acidosis with topiramate and zonisamide: an assessment of its severity and predictors

M. Pirmohamed, A. Marson, A. Alfirevic, 2011, Pharmacogenetics and genomics.

Application of in Vitro T Cell Assay Using Human Leukocyte Antigen-Typed Healthy Donors for the Assessment of Drug Immunogenicity.

M. Pirmohamed, B. K. Park, D. Naisbitt, 2018, Chemical research in toxicology.

Safety perspectives on presently considered drugs for the treatment of COVID‐19

Amy E. Chadwick, M. Pirmohamed, S. Khoo, 2020, British journal of pharmacology.

Genome and transcriptome profiling of spontaneous preterm birth phenotypes

B. Müller-Myhsok, Z. Alfirevic, A. Alfirevic, 2022, Scientific Reports.

Genome and transcriptome profiling of spontaneous preterm birth phenotypes

B. Müller-Myhsok, Z. Alfirevic, A. Alfirevic, 2022, Scientific reports.

Maternal selenium levels and whole genome screen in recurrent spontaneous preterm birth population: A nested case control study.

B. Müller-Myhsok, L. Muglia, Z. Alfirevic, 2021, European Journal of Obstetrics, Gynecology, and Reproductive Biology.

Shared Genetic Risk Factors Across Carbamazepine‐Induced Hypersensitivity Reactions

A. Morris, M. Daly, M. Nelson, 2019, Clinical pharmacology and therapeutics.

Genome-Wide Association Study of Nevirapine Hypersensitivity in a sub-Saharan 1 African HIV-infected Population 2 3

Munir, Elizabeth, Pirmohamed, 2016 .

Genetic associations with clozapine-induced myocarditis in patients with schizophrenia

A. Morris, H. Shah, R. Sebra, 2020, Translational Psychiatry.

Effect of Genetic Variability in the CYP4F2, CYP4F11, and CYP4F12 Genes on Liver mRNA Levels and Warfarin Response

P. Deloukas, M. Pirmohamed, A. Alfirevic, 2017, Front. Pharmacol..

Effects of CYP4F2 genetic polymorphisms and haplotypes on clinical outcomes in patients initiated on warfarin therapy

M. Pirmohamed, P. Williamson, A. Alfirevic, 2009, Pharmacogenetics and genomics.

Predictive Genetic Testing for Drug‐Induced Liver Injury: Considerations of Clinical Utility

M. Pirmohamed, A. Alfirevic, 2012, Clinical pharmacology and therapeutics.

Low dose aspirin and pregnancy: how important is aspirin resistance?

Z. Alfirevic, A. Alfirevic, K. Navaratnam, 2016, BJOG : an international journal of obstetrics and gynaecology.

Practical recommendations for pharmacogenomics-based prescription: 2010 ESF-UB Conference on Pharmacogenetics and Pharmacogenomics.

U. Amstutz, H. Brauch, M. Niemi, 2011, Pharmacogenomics.

The Role of Mitochondrial DNA Variation in Drug Response: A Systematic Review

Amy E. Chadwick, A. Alfirevic, Samantha W. Jones, 2021, Frontiers in Genetics.

Genome-wide association study of angioedema induced by angiotensin-converting enzyme inhibitor and angiotensin receptor blocker treatment

C. Wadelius, N. Eriksson, A. Syvänen, 2020, The Pharmacogenomics Journal.

Examining the uptake of predictive BRCA testing in the UK; findings and implications

M. Pirmohamed, A. Alfirevic, B. Godman, 2020, European Journal of Human Genetics.

Allele frequency net 2015 update: new features for HLA epitopes, KIR and disease and HLA adverse drug reaction associations

Andrew R. Jones, Faviel F. Gonzalez-Galarza, Louise Y. C. Takeshita, 2014, Nucleic Acids Res..

Implementation of genotype-guided dosing of warfarin with point-of-care genetic testing in three UK clinics: a matched cohort study

M. Pirmohamed, A. Alfirevic, A. Jorgensen, 2019, BMC Medicine.

Adverse drug reactions and pharmacogenomics: recent advances.

M. Pirmohamed, A. Alfirevic, 2008, Personalized medicine.

Genetic testing for prevention of severe drug-induced skin rash.

M. Pirmohamed, A. Alfirevic, Tess E. Cooper, 2013, The Cochrane database of systematic reviews.

Genetics of Immune-Mediated Adverse Drug Reactions: a Comprehensive and Clinical Review

M. Pirmohamed, A. Alfirevic, V. Yip, 2015, Clinical Reviews in Allergy & Immunology.

In silico analysis of HLA associations with drug-induced liver injury: use of a HLA-genotyped DNA archive from healthy volunteers

M. Pirmohamed, B. K. Park, D. Naisbitt, 2012, Genome Medicine.

TNF-α promoter region gene polymorphisms in HIV-positive patients with lipodystrophy

M. Pirmohamed, B. K. Park, A. Alfirevic, 2002 .

Molecular and genetic association of interleukin-6 in tacrine-induced hepatotoxicity

M. Pirmohamed, B. J. Barratt, B. Kevin Park, 2007, Pharmacogenetics and genomics.

Assessment of the impact of mitochondrial genotype upon drug-induced mitochondrial dysfunction in platelets derived from healthy volunteers

Amy E. Chadwick, L. Rainbow, J. Kenny, 2021, Archives of Toxicology.

Patient ethnicity and the risk of immune-mediated adverse drug reactions.

A. Alfirevic, 2017, Pharmacogenomics.

Human leukocyte antigen (HLA)‐B*57:01‐restricted activation of drug‐specific T cells provides the immunological basis for flucloxacillin‐induced liver injury

M. Pirmohamed, Andrew Gibson, B. K. Park, 2013, Hepatology.

TNF-alpha promoter region gene polymorphisms in HIV-positive patients with lipodystrophy.

M. Pirmohamed, B. K. Park, A. Alfirevic, 2002, AIDS.

Exome Sequencing Reveals Common and Rare Variants in F5 Associated With ACE Inhibitor and Angiotensin Receptor Blocker–Induced Angioedema

N. Eriksson, A. Syvänen, P. Magnusson, 2020, Clinical pharmacology and therapeutics.

Trastuzumab uptake in HER2-positive breast cancer patients: a systematic review and meta-analysis of observational studies.

A. Haycox, M. Pirmohamed, A. Alfirevic, 2018, Critical reviews in oncology/hematology.

Characterization of Clozapine-Responsive Human T Cells

M. Pirmohamed, B. K. Park, D. Naisbitt, 2020, The Journal of Immunology.

Lamotrigine is a substrate for OCT1 in brain endothelial cells.

M. Pirmohamed, P. Couraud, D. Dickens, 2012, Biochemical pharmacology.

ABCB1 single nucleotide polymorphisms (1236C>T, 2677G>T, and 3435C>T) do not affect transport activity of human P-glycoprotein

M. Pirmohamed, D. Dickens, A. Alfirevic, 2013, Pharmacogenetics and genomics.

Cost-effectiveness analysis of HLA B*5701 genotyping in preventing abacavir hypersensitivity.

M. Pirmohamed, D. Hughes, B. K. Park, 2004, Pharmacogenetics.

Chapter 10 – Pharmacogenetics and Pharmacogenomics

M. Pirmohamed, A. Alfirevic, 2016 .

How important is aspirin adherence when evaluating effectiveness of low-dose aspirin?

M. Pirmohamed, Z. Alfirevic, A. Alfirevic, 2017, European journal of obstetrics, gynecology, and reproductive biology.

Phenotype Standardization for Statin-Induced Myotoxicity

D. Voora, B. Psaty, M. Pirmohamed, 2014, Clinical pharmacology and therapeutics.

An assessment of the impact of pharmacogenomics on health disparities: a systematic literature review.

A. Haycox, M. Pirmohamed, N. Fleeman, 2017, Pharmacogenomics.

Pharmacogenomics of statin-related myopathy: Meta-analysis of rare variants from whole-exome sequencing

A. Morris, R. Gibbs, E. Boerwinkle, 2019, PloS one.

Genomewide Association Study of Statin‐Induced Myopathy in Patients Recruited Using the UK Clinical Practice Research Datalink

B. Psaty, M. Pirmohamed, M. Molokhia, 2019, Clinical pharmacology and therapeutics.

GATM gene variants and statin myopathy risk

M. Pirmohamed, D. Carr, A. Alfirevic, 2014, Nature.

TNF-α promoter region gene polymorphisms in patients with alcohol-induced chronic pancreatitis

M. Pirmohamed, W. Greenhalf, J. Neoptolemos, 2001 .

Randomized Controlled Trial: Lisinopril Reduces Proteinuria, Ammonia, and Renal Polypeptide Tubular Catabolism in Patients With Chronic Allograft Nephropathy

M. Pirmohamed, A. Alfirevic, A. Shenkin, 2010, Transplantation.

Characterization of Drug-Specific CD4+ T-Cells Reveals Possible Roles of HLA Class II in the Pathogenesis of Carbamazepine Hypersensitivity Reactions

M. Pirmohamed, D. Naisbitt, A. Alfirevic, 2023, Chemical research in toxicology.

Corrections

M. Pirmohamed, B. K. Park, Andrew Gibson, 2008, The Lancet Neurology.

Processes and barriers to implementation of point-of-care genotype-guided dosing of warfarin into UK outpatient anticoagulation clinics.

M. Pirmohamed, A. Alfirevic, J. Downing, 2019, Pharmacogenomics.

Safety pharmacology--current and emerging concepts.

Dominic P. Williams, J. Sidaway, S. Sethu, 2013, Toxicology and applied pharmacology.

Has the introduction of direct oral anticoagulants (DOACs) in England increased emergency admissions for bleeding conditions? A longitudinal ecological study

M. Pirmohamed, B. Barr, A. Alfirevic, 2020, BMJ Open.

A common missense variant of LILRB5 is associated with statin intolerance and myalgia

P. Ridker, D. Chasman, M. Pirmohamed, 2017, European heart journal.

CKM Glu83Gly Is Associated With Blunted Creatine Kinase Variation, but Not With Myalgia

P. Ridker, D. Chasman, M. Pirmohamed, 2017, Circulation. Cardiovascular genetics.

Gly is associated blunted creatine kinase variation , but not with myalgia Running title : CKM Glu 83 Gly , creatine kinase and myalgia

Munir, Pirmohamed, P. Ridker, 2017 .

Trends in BRCA testing and socioeconomic deprivation

M. Pirmohamed, A. Alfirevic, B. Godman, 2019, European Journal of Human Genetics.

Pharmacogenetics and pharmacogenomics: adverse drug reactions.

A. Alfirevic, A. Jorgensen, 2008, Pharmacogenomics.

A microRNA-based prediction algorithm for diagnosis of non-small lung cell carcinoma in minimal biopsy material

T. Liloglou, A. Alfirevic, R. Hyde, 2013, British Journal of Cancer.

Developing In Vitro Models to Define the Role of Direct Mitochondrial Toxicity in Frequently Reported Drug-Induced Rhabdomyolysis

Amy E. Chadwick, A. Alfirevic, Faten F Bin Dayel, 2023, Biomedicines.

A Multi-System Approach Assessing the Interaction of Anticonvulsants with P-gp

M. Pirmohamed, P. Couraud, D. Dickens, 2013, PloS one.

A web resource for mining HLA associations with adverse drug reactions: HLA-ADR

Andrew R. Jones, Yenal Dundar, Faviel F. Gonzalez-Galarza, 2016, Database J. Biol. Databases Curation.

Activation of carbamazepine-responsive T-cell clones with metabolically inert halogenated derivatives.

M. Pirmohamed, B. K. Park, D. Naisbitt, 2013, Journal of Allergy and Clinical Immunology.

The d3/fl-GH receptor gene polymorphism does not influence quality of life and body composition in GH-deficient adults receiving GH replacement therapy.

M. Pirmohamed, A. Alfirevic, M. Javadpour, 2009, European journal of endocrinology.

7th Drug hypersensitivity meeting: part two

S. Mallal, A. Borobia, P. Korošec, 2016, Clinical and Translational Allergy.

Genome-wide common and rare variant analysis provides novel insights into clozapine-associated neutropenia

H. Stefánsson, D. Rujescu, A. Jonasdottir, 2016, Molecular Psychiatry.

Genome-wide common and rare variant analysis provides novel insights into clozapine-associated neutropenia

M. Daly, H. Stefánsson, D. Rujescu, 2016, Molecular Psychiatry.

Public involvement in the dissemination of the North West Coast Household Health Survey: Experiences and lessons of co‐producing research together

R. Corcoran, B. Barr, A. Alfirevic, 2019, Health expectations : an international journal of public participation in health care and health policy.

in the of the North West Coast Household Health Survey: Experiences and lessons of co-producing research together in the of the North West Coast Household Health Survey: Experiences and lessons of co-producing research together. Health

A. Alfirevic, M. Gabbay, J. Downing, 2020 .

SPECIAL ECONOMIC ZONES: THE IMPACT AND IMPLICATIONS ON ECONOMIC ROWTH WITH REFERENCE TO THE CHINESE MODEL

A. Alfirevic, Dražen Marjanac, 2020 .

Association of maternal prenatal selenium concentration and preterm birth: a multicountry meta-analysis

J. Hirst, S. Murphy, L. Muglia, 2021, BMJ Global Health.

Deletion of exon 3 in the growth hormone receptor gene in adults with growth hormone deficiency: comparison of symptomatic and asymptomatic patients

M. Pirmohamed, A. Alfirevic, M. Javadpour, 2010, Clinical Endocrinology.

Publisher Correction: Genome and transcriptome profiling of spontaneous preterm birth phenotypes

B. Müller-Myhsok, Z. Alfirevic, A. Alfirevic, 2022, Scientific Reports.

ABCB1 single nucleotide polymorphisms (1236C>T, 2677G>T, and 3435C>T) do not affect transport activity of human P-glycoprotein

M. Pirmohamed, D. Dickens, A. Alfirevic, 2013, Pharmacogenetics and genomics.

Practical recommendations for pharmacogenomics-based prescription: 2010 ESF-UB Conference on Pharmacogenetics and Pharmacogenomics.

U. Amstutz, H. Brauch, M. Niemi, 2011, Pharmacogenomics.

CKM Glu83Gly Is Associated With Blunted Creatine Kinase Variation, but Not With Myalgia

P. Ridker, D. Chasman, M. Pirmohamed, 2017, Circulation. Cardiovascular genetics.

Genetic testing for prevention of severe drug-induced skin rash.

M. Pirmohamed, A. Alfirevic, Tess E. Cooper, 2019, The Cochrane database of systematic reviews.

Genetic testing for prevention of severe drug-induced skin rash.

M. Pirmohamed, A. Alfirevic, Andrea L. Jorgensen, 2013 .

T-cells from HLA-B*57:01+ human subjects are activated with abacavir through two independent pathways and induce cell death by multiple mechanisms.

M. Pirmohamed, D. Naisbitt, A. Alfirevic, 2013, Chemical research in toxicology.

Trastuzumab uptake in HER2-positive breast cancer patients: a systematic review and meta-analysis of observational studies.

A. Haycox, M. Pirmohamed, A. Alfirevic, 2018, Critical reviews in oncology/hematology.

Safety perspectives on presently considered drugs for the treatment of COVID‐19

M. Pirmohamed, A. Alfirevic, A. Owen, 2020, British journal of pharmacology.

Drug-induced hypersensitivity reactions and pharmacogenomics: past, present and future.

M. Pirmohamed, A. Alfirevic, 2010, Pharmacogenomics.

STIMULATING INNOVATIONS AND PERFORMANCE OF COMPANIES IN BOSNIA AND HERZEGOVINA

Christian Stipanović, Andrijana Ostojić Mihić, Ana-Marija Alfirević, 2016 .

Human leukocyte antigen (HLA)‐B*57:01‐restricted activation of drug‐specific T cells provides the immunological basis for flucloxacillin‐induced liver injury

M. Pirmohamed, Andrew Gibson, D. Naisbitt, 2013, Hepatology.

This information is current as Receptors β That Express Distinct V Specific T Cells − Priming of Drug Hapten The Effect of Inhibitory Signals on the

M. Pirmohamed, Andrew Gibson, D. Naisbitt, 2017 .

Institutional profile: the Wolfson Centre for Personalised Medicine, University of Liverpool, Liverpool, UK.

M. Pirmohamed, S. Pushpakom, D. Carr, 2013, Pharmacogenomics.

Role of Transporters and Enzymes in Metabolism and Distribution of 4-Chlorokynurenine (AV-101)

M. Pirmohamed, A. Alfirevic, David Dickens, 2024, Molecular pharmaceutics.

Role of transporters and enzymes in metabolism and distribution of 4 chlorokynurenine and metabolites

M. Pirmohamed, A. Alfirevic, David Dickens, 2023, bioRxiv.

Aspirin non-responsiveness in pregnant women at high-risk of pre-eclampsia.

Z. Alfirevic, A. Alfirevic, A. Jorgensen, 2018, European journal of obstetrics, gynecology, and reproductive biology.