A. Norrby-Teglund

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Necrotizing Soft Tissue Infections: Clinical and Pathogenic Aspects

Wim E Crusio, Haidong Dong, A. Norrby-Teglund, 2020, Advances in Experimental Medicine and Biology.

Integrated univariate, multivariate and correlation-based network analyses reveal metabolite-specific effects on bacterial growth and biofilm formation in necrotizing soft tissue infections.

V. M. D. Martins dos Santos, A. Norrby-Teglund, M. Svensson, 2019, Journal of proteome research.

Protein SIC Secreted from Streptococcus pyogenes Forms Complexes with Extracellular Histones That Boost Cytokine Production

L. Björck, A. Norrby-Teglund, I. Frick, 2018, Front. Immunol..

Analysis of host-pathogen gene association networks reveals patient-specific response to streptococcal and polymicrobial necrotising soft tissue infections

V. M. D. Martins dos Santos, Lorna Morris, T. Nedrebø, 2022, BMC Medicine.

Molecular and clinical characteristics of invasive group A streptococcal infection in Sweden.

A. Sandgren, A. Norrby-Teglund, B. H. Normark, 2007, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Rectal Nitric Oxide Gas and Stool Cytokine Levels during the Course of Infectious Gastroenteritis

A. Norrby-Teglund, E. Weitzberg, J. Lundberg, 2004, Clinical Diagnostic Laboratory Immunology.

Kinin receptor expression during Staphylococcus aureus infection.

A. Norrby-Teglund, H. Herwald, M. Mörgelin, 2006, Blood.

Necrotizing skin and soft tissue infections in the intensive care unit.

J. D. De Waele, A. Norrby-Teglund, S. Skrede, 2019, Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases.

Fever in the Emergency Department Predicts Survival of Patients With Severe Sepsis and Septic Shock Admitted to the ICU*

Jonas Björk, A. Norrby-Teglund, J. Björk, 2017, Critical care medicine.

Extracellular Adherence Protein from Staphylococcus aureus Enhances Internalization into Eukaryotic Cells

A. Norrby-Teglund, M. Hussain, M. Herrmann, 2003, Infection and Immunity.

HMGB1 in severe soft tissue infections caused by Streptococcus pyogenes

A. Norrby-Teglund, P. Sendi, C. Treutiger, 2014, Front. Cell. Infect. Microbiol..

Molecular profiling of tissue biopsies reveals unique signatures associated with streptococcal necrotizing soft tissue infections

T. Nedrebø, A. Norrby-Teglund, M. Svensson, 2019, Nature Communications.

Successful management of severe group A streptococcal soft tissue infections using an aggressive medical regimen including intravenous polyspecific immunoglobulin together with a conservative surgical approach

J. Bohnen, A. Norrby-Teglund, D. Low, 2005, Scandinavian journal of infectious diseases.

Evidence for superantigen involvement in severe group a streptococcal tissue infections.

A. Norrby-Teglund, M. Kotb, D. Low, 2001, The Journal of infectious diseases.

Variations in emm Type among Group A Streptococcal Isolates Causing Invasive or Noninvasive Infections in a Nationwide Study

A. Norrby-Teglund, S. Hoffmann, H. Konradsen, 2005, Journal of Clinical Microbiology.

Differential induction of Th1 versus Th2 cytokines by group A streptococcal toxic shock syndrome isolates

A. Norrby-Teglund, M. Kotb, R. Lustig, 1997, Infection and immunity.

Correlation between serum TNF alpha and IL6 levels and severity of group A streptococcal infections.

A. Norrby-Teglund, S. Holm, M. Norgren, 1995, Scandinavian journal of infectious diseases.

Detection and nucleotide sequence analysis of the speC gene in Swedish clinical group A streptococcal isolates

A. Norrby-Teglund, S. Holm, M. Norgren, 1994, Journal of clinical microbiology.

Superantigenic properties of the group A streptococcal exotoxin SpeF (MF)

A. Norrby-Teglund, M. Kotb, S. Holm, 1994, Infection and immunity.

Relation between low capacity of human sera to inhibit streptococcal mitogens and serious manifestation of disease.

A. Norrby-Teglund, S. Holm, M. Norgren, 1994, The Journal of infectious diseases.

U. Andersson, A. Norrby-Teglund, J. Andersson, 1994, Infection and immunity.

Immunopathogenesis of streptococcal deep tissue infections.

A. Norrby-Teglund, L. Johansson, 2013, Current topics in microbiology and immunology.

Severe streptococcal infection is associated with M protein‐induced platelet activation and thrombus formation

L. Björck, A. Norrby-Teglund, M. Mörgelin, 2007, Molecular microbiology.

Cathelicidin LL-37 in Severe Streptococcus pyogenes Soft Tissue Infections in Humans

A. Norrby-Teglund, D. Low, P. Sendi, 2008, Infection and Immunity.

CD46 Contributes to the Severity of Group A Streptococcal Infection

A. Norrby-Teglund, Hong Sjölinder, A. Jonsson, 2008, Infection and Immunity.

M Protein, a Classical Bacterial Virulence Determinant, Forms Complexes with Fibrinogen that Induce Vascular Leakage

L. Björck, L. Lindbom, A. Norrby-Teglund, 2004, Cell.

Risk factors in the pathogenesis of invasive group A streptococcal infections: role of protective humoral immunity.

B. Schwartz, A. Norrby-Teglund, M. Kotb, 1999, Infection and immunity.

Modelling staphylococcal pneumonia in a human 3D lung tissue model system delineates toxin-mediated pathology

F. Vandenesch, G. Lina, A. Norrby-Teglund, 2015, Disease Models & Mechanisms.

Human polyspecific immunoglobulin attenuates group A streptococcal virulence factor activity and reduces disease severity in a murine necrotizing fasciitis model.

A. Norrby-Teglund, F. Andreoni, A. Zinkernagel, 2019, Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases.

Viable Group A Streptococci in Macrophages during Acute Soft Tissue Infection

A. Norrby-Teglund, M. Kotb, D. Low, 2006, PLoS medicine.

Severe Invasive Group a Streptococcal Infections

A. Norrby-Teglund, M. Kotb, D. Low, 2004 .

Bacterial Phenotype Variants in Group B Streptococcal Toxic Shock Syndrome

V. Nizet, N. V. van Sorge, A. Norrby-Teglund, 2009, Emerging infectious diseases.

Association of Human Leukocyte Antigen with Outcomes of Infectious Diseases: The Streptococcal Experience

A. Norrby-Teglund, M. Kotb, D. Low, 2003, Scandinavian journal of infectious diseases.

Evidence for the presence of streptococcal-superantigen-neutralizing antibodies in normal polyspecific immunoglobulin G

R. Kaul, U. Andersson, A. Norrby-Teglund, 1996, Infection and immunity.

pyogenes Streptococcus Infection Caused by Modulates the Severity of 2 Prostaglandin E Inducible Cyclooxygenase Released

A. Norrby-Teglund, O. Goldmann, E. Medina, 2010 .

Inducible Cyclooxygenase Released Prostaglandin E2 Modulates the Severity of Infection Caused by Streptococcus pyogenes

A. Norrby-Teglund, O. Goldmann, E. Medina, 2010, The Journal of Immunology.

Increased cytotoxicity and streptolysin O activity in group G streptococcal strains causing invasive tissue infections

A. Norrby-Teglund, M. Svensson, O. Hyldegaard, 2015, Scientific Reports.

Intravenous Immunoglobulin Therapy in Superantigen-Mediated Toxic Shock Syndrome

A. Norrby-Teglund, M. Kotb, D. Low, 2007 .

Intravenous Immunoglobulin Adjunctive Therapy in Patients with Streptococcal Toxic Shock Syndrome and Necrotizing Fasciitis

A. Norrby-Teglund, M. Kotb, D. Low, 2003 .

Cytokine Patterns in Severe Invasive Group A Streptococcal Infections

A. Norrby-Teglund, M. Kotb, 2003 .

Intravenous Immunoglobulin Adjunctive Therapy in Sepsis, with Special Emphasis on Severe Invasive Group A Streptococcal Infections

A. Norrby-Teglund, J. Darenberg, N. Ihendyane, 2003, Scandinavian journal of infectious diseases.

Differential presentation of group A streptococcal superantigens by HLA class II DQ and DR alleles

A. Norrby-Teglund, M. Kotb, G. Nepom, 2002, European journal of immunology.

Relative neutralizing activity in polyspecific IgM, IgA, and IgG preparations against group A streptococcal superantigens.

L. Hammarström, A. Norrby-Teglund, M. Kotb, 2000, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Risk Factors in the Pathogenesis of Invasive Group A Streptococcal Infections: Role of Protective Humoral Immunity

B. Schwartz, A. Norrby-Teglund, M. Kotb, 1999, Infection and Immunity.

Getting under the skin: the immunopathogenesis of Streptococcus pyogenes deep tissue infections.

A. Norrby-Teglund, D. Low, L. Johansson, 2010, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Immunoregulation of Neutrophil Extracellular Trap Formation by Endothelial-Derived p33 (gC1q Receptor)

A. Norrby-Teglund, H. Herwald, O. Hyldegaard, 2017, Journal of Innate Immunity.

Bacterial deception of MAIT cells in a cloud of superantigen and cytokines

A. Norrby-Teglund, E. Leeansyah, J. Sandberg, 2017, PLoS biology.

Invasive Group B Streptococcal Disease in Non-pregnant Adults

A. Norrby-Teglund, P. Sendi, L. Johansson, 2008, Infection.

LL-37 Triggers Formation of Streptococcus pyogenes Extracellular Vesicle-Like Structures with Immune Stimulatory Properties

M. Rohde, B. Kreikemeyer, A. Norrby-Teglund, 2015, Journal of Innate Immunity.

M1 Protein-Dependent Intracellular Trafficking Promotes Persistence and Replication of Streptococcus pyogenes in Macrophages

A. Norrby-Teglund, M. Kotb, M. Mörgelin, 2010, Journal of Innate Immunity.

Genetic Architecture of Group A Streptococcal Necrotizing Soft Tissue Infections in the Mouse

J. Hur, A. Norrby-Teglund, M. Svensson, 2016, PLoS pathogens.

Levels of Alpha-Toxin Correlate with Distinct Phenotypic Response Profiles of Blood Mononuclear Cells and with agr Background of Community-Associated Staphylococcus aureus Isolates

F. Vandenesch, G. Lina, A. Norrby-Teglund, 2014, PloS one.

Opsonic Antibodies to the Surface M Protein of Group A Streptococci in Pooled Normal Immunoglobulins (IVIG): Potential Impact on the Clinical Efficacy of IVIG Therapy for Severe Invasive Group A Streptococcal Infections

B. Schwartz, A. Norrby-Teglund, M. Kotb, 1998, Infection and Immunity.

Release of SpeA from Streptococcus pyogenes after exposure to penicillin: Dependency on dose and inhibition by clindamycin

A. Norrby-Teglund, J. Sjölin, E. Tano, 2006, Scandinavian journal of infectious diseases.

Intravenous immunoglobulin therapy for streptococcal toxic shock syndrome--a comparative observational study. The Canadian Streptococcal Study Group.

R. Kaul, B. Schwartz, A. Norrby-Teglund, 1999, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Plasma from patients with severe invasive group A streptococcal infections treated with normal polyspecific IgG inhibits streptococcal superantigen-induced T cell proliferation and cytokine production.

R. Kaul, U. Andersson, A. Norrby-Teglund, 1996, Journal of immunology.

Myositis, Pyomyositis, and Necrotizing Fasciitis

A. Norrby-Teglund, D. Low, 2008 .

Genome Sequencing Unveils a Novel Sea Enterotoxin-Carrying PVL Phage in Staphylococcus aureus ST772 from India

R. Srinivasan, A. Seshasayee, A. Norrby-Teglund, 2013, PloS one.

Prothrombotic and Proinflammatory Activities of the β-Hemolytic Group B Streptococcal Pigment

M. Lalk, M. Rohde, A. Norrby-Teglund, 2019, Journal of Innate Immunity.

Severe group A streptococcal infections in Uppsala County, Sweden: Clinical and molecular characterization of a case cluster from 2006 to 2007

A. Norrby-Teglund, S. Sylvan, A. Melhus, 2009, Scandinavian journal of infectious diseases.

The Karolinska KI/K COVID‐19 immune atlas: An open resource for immunological research and educational purposes

H. Ljunggren, J. Klingström, O. Rooyackers, 2022, Scandinavian journal of immunology.

Polyspecific intravenous immunoglobulin in clindamycin-treated patients with 1 streptococcal toxic shock syndrome : a systematic review and meta-analysis 2 3

T. Parks, A. Norrby-Teglund, N. Curtis, 2019 .

Title: High-dimensional profiling reveals phenotypic heterogeneity and disease-specific alterations of granulocytes in COVID-19 2

H. Ljunggren, A. Sönnerborg, A. Norrby-Teglund, 2021 .

Risk Factors and Predictors of Mortality in Streptococcal Necrotizing Soft-tissue Infections: A Multicenter Prospective Study

V. M. D. Martins dos Santos, T. Nedrebø, A. Norrby-Teglund, 2020, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Clinical and Microbiologic Characteristics of Invasive Streptococcus pyogenes Infections in North and South India

R. Kumar, A. Nerlich, G. S. Chhatwal, 2012, Journal of Clinical Microbiology.

Coagulation, an ancestral serine protease cascade, exerts a novel function in early immune defense.

A. Norrby-Teglund, H. Herwald, M. Mörgelin, 2011, Blood.

COVID‐19‐specific metabolic imprint yields insights into multiorgan system perturbations

H. Ljunggren, J. Klingström, O. Rooyackers, 2021, European journal of immunology.

Soluble M1 protein of Streptococcus pyogenes triggers potent T cell activation

A. Norrby-Teglund, M. Kotb, H. Herwald, 2007, Cellular microbiology.

Superantigenic activity produced by group A streptococcal isolates is neutralized by plasma from IVIG-treated streptococcal toxic shock syndrome patients.

A. Norrby-Teglund, M. Kotb, D. Low, 1997, Advances in experimental medicine and biology.

Detection andNucleotide Sequence Analysis ofthespeCGene inSwedish Clinical GroupA Streptococcal Isolates

A. Norrby-Teglund, 1994 .

Decision support system and outcome prediction in a cohort of patients with necrotizing soft-tissue infections

A. Norrby-Teglund, S. Skrede, E. Saccenti, 2022, Int. J. Medical Informatics.

Adjunctive Rifampicin Increases Antibiotic Efficacy in Group A Streptococcal Tissue Infection Models

M. Morgan, A. Norrby-Teglund, M. Svensson, 2021, Antimicrobial agents and chemotherapy.

Intravenous polyclonal IgM‐enriched immunoglobulin therapy in sepsis: a review of clinical efficacy in relation to microbiological aetiology and severity of sepsis

L. Hammarström, A. Norrby-Teglund, K. Haque, 2006, Journal of internal medicine.

Sequence variability is correlated with weak immunogenicity in Streptococcus pyogenes M protein

G. Lindahl, A. Norrby-Teglund, B. Kristensen, 2015, MicrobiologyOpen.

The Hypervariable region of Streptococcus pyogenes M protein escapes antibody attack by antigenic variation and weak immunogenicity.

G. Lindahl, A. Norrby-Teglund, J. Lannergård, 2011, Cell host & microbe.

Group A Streptococcal DNase Sda1 Impairs Plasmacytoid Dendritic Cells' Type 1 Interferon Response.

O. Boyman, A. Norrby-Teglund, O. Hyldegaard, 2019, The Journal of investigative dermatology.

Neutrophil-Derived Hyperresistinemia in Severe Acute Streptococcal Infections1

A. Norrby-Teglund, H. Herwald, C. Treutiger, 2009, The Journal of Immunology.

Streptococcus agalactiae in relapsing cellulitis.

A. Norrby-Teglund, W. Zimmerli, P. Sendi, 2007, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Antibodies against a Surface Protein of Streptococcus pyogenes Promote a Pathological Inflammatory Response

L. Björck, A. Norrby-Teglund, H. Herwald, 2008, PLoS pathogens.

Phosphoglycerate Kinase-A Novel Streptococcal Factor Involved in Neutrophil Activation and Degranulation.

A. Norrby-Teglund, P. Bergman, Y. Kai-Larsen, 2016, The Journal of infectious diseases.

Shocking superantigens promote establishment of bacterial infection

A. Norrby-Teglund, N. Siemens, 2017, Proceedings of the National Academy of Sciences.

The treatment of severe group a streptococcal infections

A. Norrby-Teglund, D. Low, S. Norrby, 2003, Current infectious disease reports.

Differential neutrophil responses to bacterial stimuli: Streptococcal strains are potent inducers of heparin-binding protein and resistin-release

B. Kreikemeyer, A. Norrby-Teglund, H. Herwald, 2016, Scientific Reports.

Necrotizing Soft Tissue Infections S.aureus - but not S.pyogenes- isolates display high rate of internalization and cytotoxicity toward human myoblasts.

V. M. D. Martins dos Santos, F. Vandenesch, P. Leblanc, 2019, The Journal of infectious diseases.

Necrotizing Soft Tissue Infections Staphylococcus aureus - but not Streptococcus pyogenes-isolates display high rate of internalization and cytotoxicity toward human myoblasts

F. Vandenesch, P. Leblanc, A. Norrby-Teglund, 2019, bioRxiv.

Viridans streptococcal septicaemia in neutropenic patients: role of proinflammatory cytokines

P. Ljungman, A. Norrby-Teglund, D. Low, 2004, Bone Marrow Transplantation.

MAIT Cells Are Major Contributors to the Cytokine Response in Group A Streptococcal Toxic Shock Syndrome

J. McCormick, I. Barrantes, A. Norrby-Teglund, 2019, Proceedings of the National Academy of Sciences.

Microbiologic Characteristics of invasive Streptococcus pyogenes Infections in 1 North and South India 2 3 Running title : Invasive S . pyogenes infections in India

A. Nerlich, A. Norrby-Teglund, N. Mehra, 2012 .

Novel superantigens from streptococcal toxic shock syndrome Streptococcus pyogenes isolates.

A. Norrby-Teglund, M. Kotb, D. Low, 1997, Advances in experimental medicine and biology.

Host variation in cytokine responses to superantigens determine the severity of invasive group A streptococcal infection

A. Norrby-Teglund, M. Kotb, D. Low, 2000, European journal of immunology.

Correlation between immunoglobulin dose administered and plasma neutralization of streptococcal superantigens in patients with necrotizing soft tissue infections.

A. Norrby-Teglund, M. Svensson, S. Skrede, 2020, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Discriminatory plasma biomarkers predict specific clinical phenotypes of necrotizing soft-tissue infections

A. Norrby-Teglund, M. Svensson, S. Skrede, 2021, The Journal of clinical investigation.

Erysipelas caused by group A streptococcus activates the contact system and induces the release of heparin-binding protein.

L. Björck, A. Norrby-Teglund, M. Mörgelin, 2010, The Journal of investigative dermatology.

Clinical efficacy of polyspecific intravenous immunoglobulin therapy in patients with streptococcal toxic shock syndrome: a comparative observational study.

A. Norrby-Teglund, B. Henriques-Normark, J. Sjölin, 2014, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

An immunogenetic and molecular basis for differences in outcomes of invasive group A streptococcal infections

Malak Kotb, Benjamin Schwartz, Glenys Thomson, 2002, Nature Medicine.

Intravenous Immunoglobulin Therapy for Streptococcal Toxic Shock Syndrome—A Comparative Observational Study

R. Kaul, B. Schwartz, A. Norrby-Teglund, 1999 .

Macrophage activation-like syndrome: an immunological entity associated with rapid progression to death in sepsis

S. Orfanos, A. Armaganidis, A. Kotanidou, 2017, BMC Medicine.

Clinical Characteristics and Histopathology in Suspected Necrotizing Soft Tissue Infections

H. K. Haugland, A. Norrby-Teglund, S. Skrede, 2022, Open forum infectious diseases.

Extracellular Histones Induce Chemokine Production in Whole Blood Ex Vivo and Leukocyte Recruitment In Vivo

A. Norrby-Teglund, H. Herwald, A. Egesten, 2015, PLoS pathogens.

Major alterations in the mononuclear phagocyte landscape associated with COVID-19 severity

F. Ginhoux, H. Ljunggren, J. Klingström, 2021, Proceedings of the National Academy of Sciences.

Perturbations in the mononuclear phagocyte landscape associated with COVID-19 disease severity

F. Ginhoux, H. Ljunggren, J. Klingström, 2020, medRxiv.

Neutrophils acquire the capacity for antigen presentation to memory CD4+ T cells in vitro and ex vivo.

R. Koup, A. Norrby-Teglund, K. Loré, 2017, Blood.

Treatment of Necrotizing Soft Tissue Infections: IVIG.

A. Norrby-Teglund, M. Madsen, H. Bergsten, 2020, Advances in experimental medicine and biology.

Persistent elevation of high mobility group box-1 protein (HMGB1) in patients with severe sepsis and septic shock*

K. Tracey, Martin L. Lee, H. Rauvala, 2005, Critical care medicine.

High-dimensional profiling reveals phenotypic heterogeneity and disease-specific alterations of granulocytes in COVID-19

H. Ljunggren, A. Sönnerborg, J. Klingström, 2021, Proceedings of the National Academy of Sciences.

Risk assessment in sepsis: a new prognostication rule by APACHE II score and serum soluble urokinase plasminogen activator receptor

I. Dimopoulou, A. Armaganidis, A. Norrby-Teglund, 2012, Critical Care.

Necrotizing soft tissue infections – a multicentre, prospective observational study (INFECT): protocol and statistical analysis plan

V. M. D. Martins dos Santos, A. Norrby-Teglund, S. Skrede, 2018, Acta anaesthesiologica Scandinavica.

High HMGB1 levels in sputum are related to pneumococcal bacteraemia but not to disease severity in community-acquired pneumonia

A. Norrby-Teglund, P. Mölling, K. Strålin, 2018, Scientific Reports.

Targeted plasma proteomics reveals signatures discriminating COVID-19 from sepsis with pneumonia

H. Ljunggren, J. Klingström, M. Pernemalm, 2023, Respiratory Research.

CHAPTER 38 – Sepsis

A. Norrby-Teglund, C. Treutiger, 2010 .

MAIT cell activation and dynamics associated with COVID-19 disease severity

H. Ljunggren, J. Klingström, O. Rooyackers, 2020, Science Immunology.

Varying titers of neutralizing antibodies to streptococcal superantigens in different preparations of normal polyspecific immunoglobulin G: implications for therapeutic efficacy.

A. Norrby-Teglund, M. Kotb, D. Low, 1998, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Prognostic Value and Therapeutic Potential of TREM-1 in Streptococcus pyogenes-Induced Sepsis

A. Norrby-Teglund, A. Beineke, O. Goldmann, 2013, Journal of Innate Immunity.

Patient’s characteristics and outcomes in necrotising soft-tissue infections: results from a Scandinavian, multicentre, prospective cohort study

V. M. D. Martins dos Santos, A. Norrby-Teglund, S. Skrede, 2019, Intensive Care Medicine.

Phagocytosis-independent antimicrobial activity of mast cells by means of extracellular trap formation.

Manfred Rohde, M. Rohde, A. Norrby-Teglund, 2008, Blood.

Intravenous immunoglobulin G therapy in streptococcal toxic shock syndrome: a European randomized, double-blind, placebo-controlled trial.

A. Norrby-Teglund, J. Andersson, J. Sjölin, 2003, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Consistent Biofilm Formation by Streptococcus pyogenes emm 1 Isolated From Patients With Necrotizing Soft Tissue Infections

A. Norrby-Teglund, S. Skrede, H. Wiker, 2022, Frontiers in Microbiology.

The role of high mobility group box-1 protein in severe sepsis

A. Norrby-Teglund, C. Treutiger, J. Sunden-Cullberg, 2006, Current opinion in infectious diseases.

Inverse Relation between Disease Severity and Expression of the Streptococcal Cysteine Protease, SpeB, among Clonal M1T1 Isolates Recovered from Invasive Group A Streptococcal Infection Cases

Malak Kotb, Donald E. Low, A. Norrby-Teglund, 2000, Infection and Immunity.

Host-microbe interactions in the pathogenesis of invasive group A streptococcal infections.

A. Norrby-Teglund, M. Kotb, 2000, Journal of medical microbiology.

Malak Kotb, Nahla Ihendyane, Donald E. Low, 2000, Infection and Immunity.

Differences in potency of intravenous polyspecific immunoglobulin G against streptococcal and staphylococcal superantigens: implications for therapy of toxic shock syndrome.

B. Söderquist, A. Norrby-Teglund, B. H. Normark, 2004, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Immunoglobulin G for patients with necrotising soft tissue infection (INSTINCT): a randomised, blinded, placebo-controlled trial

T. Lange, A. Norrby-Teglund, A. Perner, 2017, Intensive Care Medicine.

Short- and Long-Term Mortality in Severe Sepsis/Septic Shock in a Setting with Low Antibiotic Resistance: A Prospective Observational Study in a Swedish University Hospital

A. Norrby-Teglund, C. Treutiger, L. Johansson, 2013, Front. Public Health.

Association between cytokine response, the LRINEC score and outcome in patients with necrotising soft tissue infection: a multicentre, prospective study

L. Rasmussen, T. Nedrebø, A. Norrby-Teglund, 2017, Scientific Reports.

Pronounced elevation of resistin correlates with severity of disease in severe sepsis and septic shock

Martin L. Lee, A. Norrby-Teglund, J. Andersson, 2007, Critical care medicine.

Novel therapies in streptococcal toxic shock syndrome: attenuation of virulence factor expression and modulation of the host response.

A. Norrby-Teglund, D. Stevens, 1998, Current opinion in infectious diseases.

Intracellular Streptococcus pyogenes in Human Macrophages Display an Altered Gene Expression Profile

V. Nizet, A. Norrby-Teglund, M. Kotb, 2012, PloS one.

A point mutation in AgrC determines cytotoxic or colonizing properties associated with phenotypic variants of ST22 MRSA strains

F. Vandenesch, A. Norrby-Teglund, M. Svensson, 2016, Scientific Reports.

Streptococcal M Protein: A Multipotent and Powerful Inducer of Inflammation1

L. Björck, K. Riesbeck, O. Soehnlein, 2006, The Journal of Immunology.

PHAGOCYTES , GRANULOCYTES , AND MYELOPOIESIS Neutrophils acquire the capacity for antigen presentation to memory CD 4 1 T cells in vitro and ex vivo

R. Koup, A. Norrby-Teglund, K. Loré, 2017 .

Pathogenic Mechanisms of Streptococcal Necrotizing Soft Tissue Infections.

A. Norrby-Teglund, M. Svensson, J. Snäll, 2020, Advances in experimental medicine and biology.

Mucosa-Associated Invariant T Cell Hypersensitivity to Staphylococcus aureus Leukocidin ED and Its Modulation by Activation

A. Norrby-Teglund, Srikanth Mairpady Shambat, E. Leeansyah, 2022, The Journal of Immunology.

Hypersensitivity of MAIT cells to Leukocidin ED indicates a Staphylococcus aureus immune evasion mechanism targeting the innate effector cell response

A. Norrby-Teglund, E. Leeansyah, Caroline Boulouis, 2021, bioRxiv.

Reciprocal, Temporal Expression of SpeA and SpeB by Invasive M1T1 Group A Streptococcal Isolates In Vivo

Ramy K. Aziz, Rita Kansal, Malak Kotb, 2001, Infection and Immunity.

Dual effects of extracellular adherence protein from Staphylococcus aureus on peripheral blood mononuclear cells.

A. Norrby-Teglund, J. Flock, O. Shannon, 2005, The Journal of infectious diseases.

Biofilm in group A streptococcal necrotizing soft tissue infections.

M. Morgan, J. Juarez, A. Norrby-Teglund, 2016, JCI insight.

Systemic immune activation profiles in streptococcal necrotizing soft tissue infections: A prospective multicenter study.

V. M. D. Martins dos Santos, A. Norrby-Teglund, M. Svensson, 2023, Clinical immunology.

Neutrophil-derived reactive agents induce a transient SpeB negative phenotype in Streptococcus pyogenes

T. Nedrebø, A. Norrby-Teglund, M. Svensson, 2023, Journal of Biomedical Science.

The INFECT-Project: An International and Multidisciplinary Project on Necrotizing Soft Tissue Infections.

A. Norrby-Teglund, M. Svensson, 2020, Advances in Experimental Medicine and Biology.

Reduced iNOS expression in adenoids from children with otitis media with effusion

A. Norrby-Teglund, R. Uddman, L. Cardell, 2010, Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology.

Diabetes and necrotizing soft tissue infections—A prospective observational cohort study: Statistical analysis plan

A. Norrby-Teglund, S. Skrede, E. Saccenti, 2018, Acta anaesthesiologica Scandinavica.

Beyond the traditional immune response: bacterial interaction with phagocytic cells.

A. Norrby-Teglund, L. Johansson, 2013, International journal of antimicrobial agents.

Polyspecific Intravenous Immunoglobulin in Clindamycin-treated Patients With Streptococcal Toxic Shock Syndrome: A Systematic Review and Meta-analysis

T. Parks, A. Norrby-Teglund, N. Curtis, 2018, Clinical Infectious Diseases.

Reply to Arends and Harkisoen

A. Norrby-Teglund, B. Henriques-Normark, J. Sjölin, 2014, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

High HMGB1 levels in sputum are related to pneumococcal bacteraemia but not to disease severity in community-acquired pneumonia

A. Norrby-Teglund, P. Mölling, K. Strålin, 2018, Scientific Reports.

Viva Europa, a Land of Excellence in Research and Innovation for Health and Wellbeing

A. D. Meglio, L. Hood, T. Bourgeron, 2017 .

Phagocytosis-independent antimicrobial activity of mast cells by means of extracellular trap formation.

M. Rohde, A. Norrby-Teglund, M. von Köckritz-Blickwede, 2008, Blood.

Intravenous polyclonal IgM‐enriched immunoglobulin therapy in sepsis: a review of clinical efficacy in relation to microbiological aetiology and severity of sepsis

A. Norrby-Teglund, Lennart Hammarström, K. N. Haque, 2006, Journal of internal medicine.

Interplay between human STING genotype and bacterial NADase activity regulates inter-individual disease variability

E. Elhaik, J. Velarde, M. Wessels, 2023, Nature communications.

Staphylococcal protein A inflames the lungs

S. Normark, A. Norrby-Teglund, B. H. Normark, 2004, Nature Medicine.

Protein C Inhibitor—A Novel Antimicrobial Agent

A. Schmidtchen, M. Malmsten, A. Norrby-Teglund, 2009, PLoS pathogens.

Extracellular adherence protein (Eap) from Staphylococcus aureus does not function as a superantigen.

A. Norrby-Teglund, J. Flock, A. Haggar, 2010, Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases.