P. John

发表

Identification and in silico analysis of functional SNPs of human TAGAP protein: A comprehensive study

M. Arshad, A. Bhatti, P. John, 2018, PloS one.

Atrichia with papular lesions in two Pakistani consanguineous families resulting from mutations in the human hairless gene

M. Rafiq, P. John, W. Ahmad, 2005, Archives of Dermatological Research.

miRNA Databases: An Investigation of Regulatory RNAs Informatics

A. Bhatti, P. John, M. Altaf, 2013 .

LC-MS/MS-Based Serum Protein Profiling for Identification of Candidate Biomarkers in Pakistani Rheumatoid Arthritis Patients

M. Peffers, J. Anderson, A. Bhatti, 2022, Life.

The Adverse Impact of Modern Biotechnology on the Environment

A. Bhatti, P. John, Fahd Qadir, 2015 .

Mutations in MBOAT7, Encoding Lysophosphatidylinositol Acyltransferase I, Lead to Intellectual Disability Accompanied by Epilepsy and Autistic Features.

J. Vincent, A. Caglayan, R. Abou Jamra, 2016, American journal of human genetics.

The microRNA regulatory network: a far-reaching approach to the regulate the Wnt signaling pathway in number of diseases

S. Mahmood, A. Bhatti, P. John, 2016, Journal of receptor and signal transduction research.

MicroRNAs with a role in gene regulation and in human diseases

A. Bhatti, P. John, S. Ullah, 2013, Molecular Biology Reports.

Association of Pro12Ala (rs1801282) variant of PPAR gamma with Rheumatoid Arthritis in a Pakistani population

A. Bhatti, P. John, I. Ahmed, 2014, Rheumatology International.

Exploration of shared genetic susceptibility loci between type 1 diabetes and rheumatoid arthritis in the Pakistani population

E. Feingold, F. Demirci, M. Kamboh, 2019, BMC Research Notes.

Exome sequencing revealed a novel splice site variant in the ALX1 gene underlying frontonasal dysplasia

S. Basit, P. John, W. Ahmad, 2017, Clinical genetics.

Association of rs182429 variant in TAGAP with rheumatoid arthritis in Pakistani population

M. Arshad, F. Jalil, A. Bhatti, 2017 .

Data interpretation: deciphering the biological function of Type 2 diabetes associated risk loci

A. Bhatti, P. John, A. K. Kiani, 2015, Acta Diabetologica.

Comprehensive Computational Analysis of Protein Phenotype Changes Due to Plausible Deleterious Variants of Human SPTLC1 Gene

A. Bhatti, P. John, Tayyaba Sadaf, 2019, International journal of molecular and cellular medicine.

The physiological and pathophysiological role of epinephrine and nor-epinephrine in Alzheimer's disease: a short communication

A. Bhatti, P. John, M. Ashraf, 2014 .

A novel deletion mutation in the phospholipase H (LIPH) gene in a consanguineous Pakistani family with autosomal recessive hypotrichosis (LAH2)

P. John, W. Ahmad, S. I. Raza, 2009, The British journal of dermatology.

Localization of a novel locus for alopecia with mental retardation syndrome to chromosome 3q26.33–q27.3

S. Leal, P. John, W. Ahmad, 2005, Human Genetics.

Vitamin D as a Principal Factor in Mediating Rheumatoid Arthritis-Derived Immune Response

M. Kamboh, A. Bhatti, P. John, 2019, BioMed research international.

Therapeutic Potential Of Foeniculum vulgare Mill. Derived Selenium Nanoparticles In Arthritic Balb/c Mice

A. Bhatti, P. John, A. Arif, 2019, International journal of nanomedicine.

In silico analysis of SIGMAR1 variant (rs4879809) segregating in a consanguineous Pakistani family showing amyotrophic lateral sclerosis without frontotemporal lobar dementia

Amjad Ali, A. Mohyuddin, A. Bhatti, 2015, neurogenetics.

Data Integration for Big Data analytics to identify the gaps in Rheumatoid Arthritis Genomics in a Post-GWAS era

M. Peffers, A. Bhatti, P. John, 2022, 2022 2nd International Conference on Advance Computing and Innovative Technologies in Engineering (ICACITE).

Molecular docking and pharmacophore models to probe binding hypothesis of inhibitors of hypoxia inducible factor-1

A. Bhatti, P. John, Z. Rehman, 2021, Journal of biomolecular structure & dynamics.

Thymus serpyllum Exhibits Anti-Diabetic Potential in Streptozotocin-Induced Diabetes Mellitus Type 2 Mice: A Combined Biochemical and In Vivo Study

A. Bhatti, P. John, Jahanzaib Azhar, 2022, Nutrients.

Nanomedicine: an emerging era of theranostics and therapeutics for rheumatoid arthritis.

A. Bhatti, P. John, Naila Qamar, 2019, Rheumatology.

Tomorou attenuates progression of rheumatoid arthritis through alteration in ULK-1 independent autophagy pathway in collagen induced arthritis mice model

A. Bhatti, P. John, M. Hayat, 2019, Cell Death Discovery.

Emerging role of selenium in treatment of rheumatoid arthritis: An insight on its antioxidant properties.

A. Bhatti, P. John, Naila Qamar, 2021, Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements.

Toxicological and Anti-Rheumatic Potential of Trachyspermum ammi Derived Biogenic Selenium Nanoparticles in Arthritic Balb/c Mice

A. Bhatti, P. John, Naila Qamar, 2020, International journal of nanomedicine.

Case-control study of vitamin D receptor gene polymorphism in Pakistani rheumatoid arthritis patients.

A. Bhatti, P. John, Tahir Iqbal, 2017, Revista brasileira de reumatologia.

Pure hair–nail ectodermal dysplasia maps to chromosome 12p11.1–q21.1 in a consanguineous Pakistani family

P. John, M. Naeem, W. Ahmad, 2007, Clinical and experimental dermatology.

Identification of a homozygous splice site mutation in the dynein axonemal light chain 4 gene on 22q13.1 in a large consanguineous family from Pakistan with congenital mirror movement disorder

J. Vincent, M. Rafiq, G. Rouleau, 2014, Human Genetics.

MicroRNAs with a role in gene regulation and in human diseases

A. Bhatti, P. John, S. Ullah, 2013, Molecular Biology Reports.

Immunomodulatory and therapeutic role of Cinnamomum verum extracts in collagen-induced arthritic BALB/c mice

A. Bhatti, P. John, M. Ashraf, 2017, Inflammopharmacology.

Biogenic Selenium Nanoparticles: Potential Solution to Oxidative Stress Mediated Inflammation in Rheumatoid Arthritis and Associated Complications

A. Bhatti, P. John, A. Rehman, 2021, Nanomaterials.

A mutation in the lipase H (LIPH) gene underlie autosomal recessive hypotrichosis

P. John, W. Ahmad, S. I. Raza, 2007, Human Genetics.

Interlace between Chromatin Structure, DNA Repair and Ubiquitination

A. Bhatti, P. John, Arooma Jannat, 2018, Ubiquitination Governing DNA Repair - Implications in Health and Disease.

Structural and functional annotation of PR/SET Domain (PRDM) protein family: In-silico study elaborating role of PRDM12 mutation in congenital insensitivity to pain

Amjad Ali, Sarmad Mehmood, Rubina Dad, 2020, Comput. Biol. Chem..

Single-Cell Omics in Metabolic Disorders

A. Bhatti, P. John, N. Syed, 2019, Single-Cell Omics.

MicroRNA-155 as a therapeutic target for inflammatory diseases

A. Bhatti, P. John, Naghmana Kanwal, 2013, Rheumatology International.

Identification of a homozygous missense mutation in LRP2 and a hemizygous missense mutation in TSPYL2 in a family with mild intellectual disability

J. Vincent, M. Rafiq, A. Bhatti, 2016, Psychiatric genetics.

Phosphoserine phosphatase (PSPH) gene mutation in an intellectual disability family from Pakistan

J. Vincent, M. Rafiq, E. Schaftingen, 2015, Clinical genetics.

Co-expression of HIF-1α, MDR1 and LAPTM4B in peripheral blood of solid tumors

A. Bhatti, P. John, Z. Rehman, 2019, PeerJ.

Mapping autosomal recessive intellectual disability: combined microarray and exome sequencing identifies 26 novel candidate genes in 192 consanguineous families

A. Noor, J. Vincent, M. Rafiq, 2017, Molecular Psychiatry.

Mapping of a Gene for Alopecia with Mental Retardation Syndrome (APMR3) on Chromosome 18q11.2‐q12.2

P. John, W. Ahmad, G. Ali, 2007, Annals of human genetics.

Previously described sequence variant in CDK5RAP2 gene in a Pakistani family with autosomal recessive primary microcephaly

P. John, W. Ahmad, G. Ali, 2007, BMC Medical Genetics.

Localization of a novel autosomal recessive hypotrichosis locus (LAH3) to chromosome 13q14.11–q21.32

P. John, W. Ahmad, M. Ayub, 2007, Clinical genetics.

Ectodermal dysplasia of hair and nail type: mapping of a novel locus to chromosome 17p12–q21.2

P. John, M. Naeem, W. Ahmad, 2006, The British journal of dermatology.

A novel locus for alopecia with mental retardation syndrome (APMR2) maps to chromosome 3q26.2‐q26.31

P. John, W. Ahmad, G. Ali, 2006, Clinical genetics.

The mapping of DFNB62, a new locus for autosomal recessive non‐syndromic hearing impairment, to chromosome 12p13.2‐p11.23

P. John, W. Ahmad, G. Ali, 2006, Clinical genetics.

Association of VPREB1 Gene Copy Number Variation and Rheumatoid Arthritis Susceptibility

E. Feingold, F. Demirci, M. Kamboh, 2020, Disease markers.

Genetic Susceptibility to Type 2 Diabetes and Implications for Therapy

A. Bhatti, P. John, A. K. Kiani, 2013 .

Epidemiological Investigation of Type 2 Diabetes and Alzheimer’s Disease in a Pakistani Population †

C. Loffredo, A. Bhatti, P. John, 2018, International journal of environmental research and public health.

Prevalence of type 2 diabetes–associated complications in Pakistan

Xingbin Wang, M. Kamboh, F. Jalil, 2016, International Journal of Diabetes in Developing Countries.

Mutations in DCPS and EDC3 in autosomal recessive intellectual disability indicate a crucial role for mRNA decapping in neurodevelopment.

J. Vincent, M. Rafiq, H. Sticht, 2015, Human molecular genetics.

Reverse Engineering and Its Applications

Peter John, Attya Bhatti, Nida Ali Syed, 2018 .

Transcriptional Profiling and Biological Pathway(s) Analysis of Type 2 Diabetes Mellitus in a Pakistani Population †

C. Loffredo, A. Bhatti, P. John, 2020, International journal of environmental research and public health.

Erratum to: Genetic link of type 1 diabetes susceptibility loci with rheumatoid arthritis in Pakistani patients

Xingbin Wang, F. Demirci, M. Kamboh, 2015, Immunogenetics.

Lack of association of –863C/A (rs1800630) polymorphism of tumor necrosis factor-a gene with rheumatoid arthritis

A. Bhatti, P. John, J. Malik, 2018, Archives of medical science : AMS.

Lack of tumor necrosis factor alpha gene polymorphism ‐857c/t (rs1799724) association in Pakistani rheumatoid arthritis patients

A. Bhatti, P. John, Sidra Jahangir, 2016, International journal of rheumatic diseases.

Recurrent intragenic deletion mutation in desmoglein 4 gene underlies autosomal recessive hypotrichosis in two Pakistani families of Balochi and Sindhi origins

I. Waheed, P. John, W. Ahmad, 2006, Archives of Dermatological Research.

Anti-citrullinated protein antibodies: role in pathogenesis of RA and potential as a diagnostic tool

A. Bhatti, P. John, S. Moeez, 2013, Rheumatology International.

In silico analysis of non-synonymous missense SNPs (nsSNPs) in CPE, GNAS genes and experimental validation in type II diabetes mellitus through Next Generation Sequencing.

J. Ali, A. Bhatti, P. John, 2021, Genomics.

Docking and Molecular Dynamics Study to Identify Novel Phytobiologics from Dracaena trifasciata against Metabolic Reprogramming in Rheumatoid Arthritis

R. Z. Paracha, A. Bhatti, P. John, 2022, Life.

Tomorou attenuates progression of rheumatoid arthritis through alteration in ULK-1 independent autophagy pathway in collagen induced arthritis mice model

A. Bhatti, P. John, M. Hayat, 2019, Cell Death Discovery.

Rheumatoid arthritis: What have we learned about the causing factors?

M. Arshad, A. Bhatti, P. John, 2016, Pakistan journal of pharmaceutical sciences.

Replication of European Rheumatoid Arthritis Loci in a Pakistani Population

Xingbin Wang, F. Demirci, M. Kamboh, 2013, The Journal of Rheumatology.

Homozygous mutations in NTRK 1 gene underlie congenital insensitivity to pain with anhidrosis in Pakistani families

S. Mahmood, E. Khan, P. John, 2016 .

A sequencing study of CTLA4 in Pakistani rheumatoid arthritis cases

E. Feingold, F. Demirci, M. Kamboh, 2020, PloS one.

Single-Cell Omics in Autoimmune Disorders

A. Bhatti, P. John, Shanzay Ahmed, 2019, Single-Cell Omics.

Pan-transcriptomics and its applications

A. Bhatti, P. John, F. Shah, 2020 .

T cell activation Rho GTPase activating protein (TAGAP) is upregulated in clinical and experimental arthritis

M. Arshad, F. Jalil, A. Bhatti, 2017, Cytokine.

The prognostic outcome of ‘type 2 diabetes mellitus and breast cancer’ association pivots on hypoxia-hyperglycemia axis

A. Bhatti, P. John, Ilhaam Ayaz Durrani, 2021, Cancer Cell International.

Association of Fc Gamma Receptor 3B Gene Copy Number Variation with Rheumatoid Arthritis Susceptibility

E. Feingold, F. Demirci, M. Kamboh, 2022, Genes.

Genetic link of type 1 diabetes susceptibility loci with rheumatoid arthritis in Pakistani patients

Xingbin Wang, F. Demirci, M. Kamboh, 2015, Immunogenetics.

Assessment of genetic risk of type 2 diabetes among Pakistanis based on GWAS-implicated loci.

E. Feingold, F. Demirci, M. Kamboh, 2021, Gene.

The prognostic outcome of ‘type 2 diabetes mellitus and breast cancer’ association pivots on hypoxia-hyperglycemia axis

A. Bhatti, P. John, Ilhaam Ayaz Durrani, 2021, Cancer Cell International.

Homozygosity mapping of autosomal recessive intellectual disability loci in 11 consanguineous Pakistani families

J. Vincent, M. Rafiq, A. Bhatti, 2014, Acta Neuropsychiatrica.

In silico analysis of SIGMAR1 variant (rs4879809) segregating in a consanguineous Pakistani family showing amyotrophic lateral sclerosis without frontotemporal lobar dementia

Amjad Ali, A. Mohyuddin, A. Bhatti, 2015, neurogenetics.

A replication study of 49 Type 2 diabetes risk variants in a Punjabi Pakistani population

D. Saleheen, A. Rasheed, F. Demirci, 2016, Diabetic medicine : a journal of the British Diabetic Association.

Therapeutic Potential of Selenium Nanoparticles

A. Bhatti, P. John, Maryam Zafar, 2018 .

Investigating the GWAS-Implicated Loci for Rheumatoid Arthritis in the Pakistani Population

E. Feingold, F. Demirci, M. Kamboh, 2020, Disease markers.

Polymorphisms in DNA repair genes XRCC1 and OGG1 lead to the progression of rheumatoid arthritis in Pakistani patients.

A. Bhatti, P. John, M. Ashraf, 2016, Pakistan journal of pharmaceutical sciences.

Association Study of Coronary Artery Disease-Associated Genome-Wide Significant SNPs with Coronary Stenosis in Pakistani Population

Asma N. Cheema, E. Feingold, Xingbin Wang, 2020, Disease markers.

Association of 32 type 1 diabetes risk loci in Pakistani patients.

Xingbin Wang, F. Demirci, M. Kamboh, 2015, Diabetes research and clinical practice.

Previously described sequence variant in CDK5RAP2 gene in a Pakistani family with autosomal recessive primary microcephaly

P. John, W. Ahmad, G. Ali, 2007, BMC Medical Genetics.

Molecular dynamics simulations and bioinformatics’ analysis of deleterious missense single nucleotide polymorphisms in Glyoxalase-1 gene

A. Bhatti, P. John, N. Syed, 2023, Journal of biomolecular structure & dynamics.

Identification and in silico analysis of functional SNPs of human TAGAP protein: A comprehensive study

M. Arshad, A. Bhatti, P. John, 2018, PloS one.

Mutations in MBOAT7, Encoding Lysophosphatidylinositol Acyltransferase I, Lead to Intellectual Disability Accompanied by Epilepsy and Autistic Features.

J. Vincent, R. Abou Jamra, J. Gleeson, 2016, American journal of human genetics.

Molecular Link between Glo-1 Expression and Markers of Hyperglycemia and Oxidative Stress in Vascular Complications of Type 2 Diabetes Mellitus

A. Bhatti, P. John, N. Syed, 2023, Antioxidants.

Annotation of Type 1 Diabetes Functional Variants Through RegulomeDB

P. John, Sidra Jahangir, A. K. Kiani, 2018, Advances in Intelligent Systems and Computing.

Mutations in DCPS and EDC3 in autosomal recessive intellectual disability indicate a crucial role for mRNA decapping in neurodevelopment.

M. Rafiq, H. Sticht, A. Reis, 2015, Human Molecular Genetics.

Association analysis of Vascular Endothelial Growth Factor-A (VEGF-A) polymorphism in rheumatoid arthritis using computational approaches

A. Bhatti, P. John, Iraj Ahmed, 2023, Scientific reports.

Dual inhibition of glycolysis and glutaminolysis for synergistic therapy of rheumatoid arthritis

A. Bhatti, P. John, S. Kemble, 2023, Arthritis Research & Therapy.

Biocompatible gelatin-coated ferrite nanoparticles: A magnetic approach to advanced drug delivery

A. Bhatti, P. John, Varda Shakeel, 2024, Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society.

Identification of a homozygous splice site mutation in the dynein axonemal light chain 4 gene on 22q13.1 in a large consanguineous family from Pakistan with congenital mirror movement disorder

J. Vincent, M. Rafiq, G. Rouleau, 2014, Human Genetics.

Network medicine based approach for identifying the type 2 diabetes, osteoarthritis and triple negative breast cancer interactome: Finding the hub of hub genes

A. Bhatti, P. John, Ilhaam Ayaz Durrani, 2024, Heliyon.

Integrated bioinformatics analyses identifying potential biomarkers for type 2 diabetes mellitus and breast cancer: In SIK1-ness and health

A. Bhatti, P. John, Ilhaam Ayaz Durrani, 2023, PloS one.