Kyeong-Man Kim

发表

Dopaminergic Supersensitivity in G Protein-Coupled Receptor Kinase 6-Deficient Mice

Marc G Caron, Laura M Bohn, Aki Laakso, 2003, Neuron.

A β-Arrestin Binding Determinant Common to the Second Intracellular Loops of Rhodopsin Family G Protein-coupled Receptors*

M. Caron, Kyeong-Man Kim, S. Marion, 2006, Journal of Biological Chemistry.

α4β2 nicotinic acetylcholine receptor downregulates D3 dopamine receptor expression through protein kinase C activation.

Kyeong-Man Kim, Srijan Acharya, 2019, Biochemical and biophysical research communications.

Effects of (-)-epigallocatechin gallate on the development of morphine-induced physical dependence

Kyeong-Man Kim, K. Oh, J. Eun, 2007, Archives of pharmacal research.

Bromocriptine activates NQO1 via Nrf2-PI3K/Akt signaling: novel cytoprotective mechanism against oxidative damage.

Kyeong-Man Kim, H. Choi, O. Hwang, 2008, Pharmacological research.

Dual regulation of mast cell degranulation through IgE receptor-mediated modulation of M2-type pyruvate kinase

Kyeong-Man Kim, S. Cheon, D. Cho, 2014, Archives of pharmacal research.

C-Src-mediated phosphorylation of δ-catenin increases its protein stability and the ability of inducing nuclear distribution of β-catenin.

W. Choi, Kyeong-Man Kim, Q. Lu, 2014, Biochimica et biophysica acta.

New designer phenethylamines 2C-C and 2C-P have abuse potential and induce neurotoxicity in rodents

Hyoung‐Chun Kim, C. Jang, Seok-Yong Lee, 2021, Archives of Toxicology.

Design and synthesis of 4-benzylpiperidine carboxamides as dual serotonin and norepinephrine reuptake inhibitors.

Kyeong-Man Kim, S. Paudel, S. Cheon, 2015, Bioorganic & medicinal chemistry.

Role of cyclooxygenase-2 in tetrahydrobiopterin-induced dopamine oxidation.

Kyeong-Man Kim, Kwang Youl Lee, H. Inoue, 2007, Biochemical and biophysical research communications.

GRK2-mediated receptor phosphorylation and Mdm2-mediated β-arrestin2 ubiquitination drive clathrin-mediated endocytosis of G protein-coupled receptors.

Kyeong-Man Kim, M. Zheng, Xiaohan Zhang, 2020, Biochemical and biophysical research communications.

Selectivity of commonly used inhibitors of clathrin-mediated and caveolae-dependent endocytosis of G protein-coupled receptors.

S. Nah, Kyeong-Man Kim, M. Oak, 2015, Biochimica et biophysica acta.

Effects of resveratrol-related hydroxystilbenes on the nitric oxide production in macrophage cells: structural requirements and mechanism of action.

W. Chung, S. Ryu, Kyeong-Man Kim, 2002, Life sciences.

β‐Arrestin1 and GPCR kinase2 play permissive roles in Src‐mediated endocytosis of α4β2 nicotinic ACh receptors

Kyeong-Man Kim, Srijan Acharya, Dooti Kundu, 2021, British journal of pharmacology.

A novel molecular mechanism responsible for phosphorylation-independent desensitization of G protein-coupled receptors exemplified by the dopamine D3 receptor.

Kyeong-Man Kim, M. Zheng, Srijan Acharya, 2020, Biochemical and biophysical research communications.

Molecular Signature That Determines the Acute Tolerance of G Protein-Coupled Receptors

Kyeong-Man Kim, C. Min, M. Zheng, 2016, Biomolecules & therapeutics.

PKCβII inhibits the ubiquitination of β‐arrestin2 in an autophosphorylation‐dependent manner

Moo-Yeol Lee, Kyeong-Man Kim, H. Choi, 2015, FEBS letters.

β-Arrestin2 Plays Permissive Roles in the Inhibitory Activities of RGS9-2 on G Protein-Coupled Receptors by Maintaining RGS9-2 in the Open Conformation

Kyeong-Man Kim, D. Cho, C. Min, 2011, Molecular and Cellular Biology.

Conceptual Progress for the Improvements in the Selectivity and Efficacy of G Protein-Coupled Receptor Therapeutics: An Overview

Kyeong-Man Kim, 2017, Biomolecules & therapeutics.

Clathrin Required for Phosphorylation and Internalization of β2-Adrenergic Receptor by G Protein-coupled Receptor Kinase 2 (GRK2)*

M. Nishida, H. Nakata, Kyeong-Man Kim, 2006, Journal of Biological Chemistry.

β-arrestin2 in Infiltrated Macrophages Inhibits Excessive Inflammation after Myocardial Infarction

M. Nishida, Kyeong-Man Kim, H. Kurose, 2013, PloS one.

Multiple regulatory roles of the carboxy terminus of Ste2p a yeast GPCR.

M. Hauser, J. Becker, M. Uddin, 2012, Pharmacological research.

Characterization of the desensitization properties of five dopamine receptor subtypes and alternatively spliced variants of dopamine D2 and D4 receptors.

M. Caron, H. V. Van Tol, Kyeong-Man Kim, 2006, Biochemical and biophysical research communications.

Agonist-induced changes in RalA activities allows the prediction of the endocytosis of G protein-coupled receptors.

Kyeong-Man Kim, M. Oak, S. Cheon, 2016, Biochimica et biophysica acta.

Functional Regulation of Dopamine D3 Receptor through Interaction with PICK1

Kyeong-Man Kim, I. Oh, C. Min, 2016, Biomolecules & therapeutics.

Characterization of functional roles of DRY motif in the 2nd intracellular loop of dopamine D2 and D3 receptors

Kyeong-Man Kim, Jae H. Park, Ju-Heon Kim, 2008, Archives of pharmacal research.

Molecular mechanisms involved in epidermal growth factor receptor-mediated inhibition of dopamine D3 receptor signaling.

Kyeong-Man Kim, H. Le, S. Guo, 2018, Biochimica et biophysica acta. Molecular cell research.

Vasorelaxant Prenylated Flavonoids from the Roots of Sophora flavescens

Kyeong-Man Kim, M. Oak, C. Kim, 2013, Bioscience, biotechnology, and biochemistry.

The tyrosine phosphorylation of GRK2 is responsible for activated D2R-mediated insulin resistance.

Kyeong-Man Kim, Li Hu, Haiping Liu, 2022, Biochemical and biophysical research communications.

Roles of G protein and beta-arrestin in dopamine D2 receptor-mediated ERK activation.

P. Albert, Kyeong-Man Kim, Ju-Heon Kim, 2008, Biochemical and biophysical research communications.

Complementary roles of the DRY motif and C-terminus tail of GPCRS for G protein coupling and beta-arrestin interaction.

M. Caron, Kyeong-Man Kim, 2008, Biochemical and biophysical research communications.

Relationship between the G protein signaling and homologous desensitization of G protein-coupled receptors.

J. Becker, Kyeong-Man Kim, L. Barak, 2006, Biochemical and biophysical research communications.

The EGF receptor inhibits the signaling of dopamine D3 receptor through the phosphorylation of GRK2 on tyrosine residues.

Kyeong-Man Kim, Xiaohan Zhang, Xiaowei Zhang, 2017, Biochemical and biophysical research communications.

N-linked Glycosylation on the N-terminus of the dopamine D2 and D3 receptors determines receptor association with specific microdomains in the plasma membrane.

K. Kwon, C. Shin, Kyeong-Man Kim, 2015, Biochimica et biophysica acta.

Agonist-induced endocytosis and receptor phosphorylation mediate resensitization of dopamine D(2) receptors.

Kyeong-Man Kim, Jae H. Park, Lan Ma, 2010, Molecular endocrinology.

Roles of conserved intracellular sequences regions for the proper expression of dopamine D2 and D3 receptors

Kyeong-Man Kim, Jae H. Park, Eun-Young Cho, 2008, Archives of pharmacal research.

Roles of Dopamine D2 Receptor Subregions in Interactions with β-Arrestin2

Kyeong-Man Kim, Xiaohan Zhang, Bo-Gil Choi, 2016, Biomolecules & therapeutics.

β-Arrestin2 directly or through GRK2 inhibits PKCβII activation in a ubiquitination-dependent manner.

Kyeong-Man Kim, M. Zheng, Xiaohan Zhang, 2018, Biochimica et biophysica acta. Molecular cell research.

Different conformational dynamics of β-arrestin1 and β-arrestin2 analyzed by hydrogen/deuterium exchange mass spectrometry.

K. Chung, Kyeong-Man Kim, M. Seo, 2015, Biochemical and biophysical research communications.

Intracellular Trafficking Assays for Dopamine D2-Like Receptors

Kyeong-Man Kim, C. Min, M. Zheng, 2015 .

Design, synthesis, and biological evaluation of arylpiperazine-benzylpiperidines with dual serotonin and norepinephrine reuptake inhibitory activities.

Kyeong-Man Kim, S. Paudel, S. Cheon, 2016, Bioorganic & medicinal chemistry.

Molecular mechanisms of inhibitory activities of tanshinones on Lipopolysaccharide-lnduced nitric oxide generation in RAW 264.7 cells

S. Ryu, Hoo-Kyun Choi, Kyeong-Man Kim, 2004, Archives of pharmacal research.

Preparation of δ-opioid receptor-specific antibodies using molecular cloned genes

Kyeong-Man Kim, Ae-young Kim, Shee-Yong Lee, 1995 .

Prevention of Ginsenoside-induced Desensitization of Ca2+-activated Cl– Current by Microinjection of Inositol Hexakisphosphate in Xenopus laevis Oocytes

Byung-Hwan Lee, S. Nah, H. Rhim, 2004, Journal of Biological Chemistry.

Identification of Cis-acting Elements and Signaling Components of High Affinity IgE Receptor that Regulate the Expression of Cyclooxygenase-2

Hoo-Kyun Choi, Kyeong-Man Kim, A. Yi, 2012, Cellular Physiology and Biochemistry.

The role of G protein in muscarinic depolarization near resting potential in cultured hippocampal neurons

Kyeong-Man Kim, Y. Nakajima, S. Nakajima, 1993, Brain Research.

Studies of structure activity relationship of flavonoids for the anti-allergic actions

S. Ryu, Kyeong-Man Kim, M. Oak, 1998, Archives of pharmacal research.

Anti-allergic and Antioxidative Activities of Some Compounds from Thai Medicinal Plants

Kyeong-Man Kim, W. Reanmongkol, P. Panichayupakaranant, 2003 .

RGS4 exerts inhibitory activities on the signaling of dopamine D2 receptor and D3 receptor through the N-terminal region.

Kyeong-Man Kim, D. Cho, C. Min, 2012, Pharmacological research.

Anti-allergic prenylated flavonoids from the roots of Sophora flavescens.

Kyeong-Man Kim, B. Um, M. Oak, 2008, Planta medica.

Novel Regulatory Mechanism of Canonical Wnt Signaling by Dopamine D2 Receptor through Direct Interaction with β-Catenin

K. Kwon, C. Shin, Kyeong-Man Kim, 2011, Molecular Pharmacology.

Current perspectives on the selective regulation of dopamine D2 and D3 receptors

Kyeong-Man Kim, D. Cho, M. Zheng, 2010, Archives of pharmacal research.

Roles of protein kinase C and actin-binding protein 280 in the regulation of intracellular trafficking of dopamine D3 receptor.

M. Caron, Kyeong-Man Kim, Jae H. Park, 2007, Molecular endocrinology.

G Protein-coupled Receptor Kinase Regulates Dopamine D3 Receptor Signaling by Modulating the Stability of a Receptor-Filamin-β-Arrestin Complex

R. Gainetdinov, M. Caron, Kyeong-Man Kim, 2005, Journal of Biological Chemistry.

Direct and biochemical interaction between dopamine D3 receptor and elongation factor-1Bbetagamma.

Hoo-Kyun Choi, Kyeong-Man Kim, M. Oak, 2003, Life sciences.

Differential Regulation of the Dopamine D2and D3 Receptors by G Protein-coupled Receptor Kinases and β-Arrestins*

M. Caron, W. Yao, Kyeong-Man Kim, 2001, The Journal of Biological Chemistry.

Exploration of substituted arylpiperazine-tetrazoles as promising dual norepinephrine and dopamine reuptake inhibitors.

Kyeong-Man Kim, S. Paudel, Goo Yoon, 2016, Bioorganic & medicinal chemistry.

Mdm2-mediated ubiquitination of β-arrestin2 in the nucleus occurs in a Gβγ- and clathrin-dependent manner.

Kyeong-Man Kim, Xiaohan Zhang, Ningning Sun, 2020, Biochemical pharmacology.

Functional Interaction between Monoamine Plasma Membrane Transporters and the Synaptic PDZ Domain–Containing Protein PICK1

A. Levey, M. Caron, W. Yao, 2001, Neuron.

Distinct effects on M2-type pyruvate kinase are involved in the dimethylsulfoxide-induced modulation of cellular proliferation and degranulation of mast cells

Kyeong-Man Kim, N. Koo, 2009, Archives of pharmacal research.

Dopamine D2 Receptor as a Cellular Component Controlling Nocturnal Hyperactivities in Drosophila melanogaster

J. Bahn, Kyeong-Man Kim, Jae H. Park, 2013, Chronobiology international.

β-Arrestin/AP-2 Interaction in G Protein-coupled Receptor Internalization

M. Caron, W. Miller, Kyeong-Man Kim, 2002, The Journal of Biological Chemistry.

beta-Arrestin/AP-2 interaction in G protein-coupled receptor internalization: identification of a beta-arrestin binging site in beta 2-adaptin.

M. Caron, W. Miller, Kyeong-Man Kim, 2002, The Journal of biological chemistry.

Roles of the Functional Interaction between Brain Cholinergic and Dopaminergic Systems in the Pathogenesis and Treatment of Schizophrenia and Parkinson’s Disease

Kyeong-Man Kim, Srijan Acharya, 2021, International journal of molecular sciences.

The Role of Phosphorylation in D1 Dopamine Receptor Desensitization

D. Sibley, Kyeong-Man Kim, P. Marinec, 2004, Journal of Biological Chemistry.

Metabotropic signaling cascade involved in α4β2 nicotinic acetylcholine receptor-mediated PKCβII activation.

Kyeong-Man Kim, H. Choi, Srijan Acharya, 2020, Biochimica et biophysica acta. Molecular cell research.

Multifactorial Regulation of G Protein-Coupled Receptor Endocytosis

Kyeong-Man Kim, Xiaohan Zhang, 2017, Biomolecules & therapeutics.

Mechanistic diversity involved in the desensitization of G protein-coupled receptors

Kyeong-Man Kim, Ningning Sun, 2021, Archives of Pharmacal Research.

Mdm2-mediated ubiquitination of PKCβII in the nucleus mediates clathrin-mediated endocytic activity.

Kyeong-Man Kim, Srijan Acharya, Xiaohan Zhang, 2019, Biochemical pharmacology.

Differentiated HT22 cells as a novel model for in vitro screening of serotonin reuptake inhibitors

Kyeong-Man Kim, H. Choi, Yeojin Bang, 2023, Frontiers in Pharmacology.

Palmitoylation of the carboxyl-terminal tail of dopamine D4 receptor is required for surface expression, endocytosis, and signaling.

Kyeong-Man Kim, Xiaowei Zhang, 2016, Biochemical and biophysical research communications.

Tanshinones Inhibit Mast Cell Degranulation by Interfering with IgE Receptor-Mediated Tyrosine Phosphorylation of PLCγ2 and MAPK

H. Choi, Kyeong-Man Kim, 2004, Planta medica.

Design, Synthesis, and Functional Evaluation of 1, 5-Disubstituted Tetrazoles as Monoamine Neurotransmitter Reuptake Inhibitors

C. Shin, Kyeong-Man Kim, Eunae Kim, 2021, Biomolecules & Therapeutics.

Developmental regulation and functions of the expression of the neuropeptide corazonin in Drosophila melanogaster

Kyeong-Man Kim, Jae H. Park, Youn-Jeong Choi, 2008, Cell and Tissue Research.

Unveiling the Differences in Signaling and Regulatory Mechanisms between Dopamine D2 and D3 Receptors and Their Impact on Behavioral Sensitization

Kyeong-Man Kim, 2023, International journal of molecular sciences.

Differential regulation of phospholipase Cγ subtypes through FcεRI, high affinity IgE receptor

E. Yoon, Kyeong-Man Kim, M. Oak, 2004 .

Heterologous down-regulation of angiotensin type 1 receptors by purinergic P2Y2 receptor stimulation through S-nitrosylation of NF-κB

M. Nishida, Kazuhide Inoue, Kyeong-Man Kim, 2011, Proceedings of the National Academy of Sciences.

A beta-arrestin binding determinant common to the second intracellular loops of rhodopsin family G protein-coupled receptors.

M. Caron, Kyeong-Man Kim, S. Marion, 2006, The Journal of biological chemistry.

Sequestration of Gβγ by deubiquitinated arrestins into the nucleus as a novel desensitization mechanism of G protein–coupled receptors

Kyeong-Man Kim, Xiaohan Zhang, Ningning Sun, 2023, Cell Communication and Signaling.

Comparative Studies of Molecular Mechanisms of Dopamine D2 and D3 Receptors for the Activation of Extracellular Signal-regulated Kinase*

M. Caron, G. Torres, Kyeong-Man Kim, 2004, Journal of Biological Chemistry.

Identification of certain sequences in the 3rd cytoplasmic loop of D4 dopamine receptor that suppress the bacterial expression

Kyeong-Man Kim, Ae-young Kim, Ji-Sook Cheong, 1996 .

Palmitoylation on the carboxyl terminus tail is required for the selective regulation of dopamine D2 versus D3 receptors.

Kyeong-Man Kim, M. Zheng, H. Le, 2016, Biochimica et biophysica acta.

Cytoplasmic recruitment of Mdm2 as a common characteristic of G protein-coupled receptors that undergo desensitization.

Kyeong-Man Kim, M. Zheng, Xiaohan Zhang, 2020, Biochemical and biophysical research communications.

Design, synthesis and docking study of 4-arylpiperazine carboxamides as monoamine neurotransmitters reuptake inhibitors.

Kyeong-Man Kim, S. Paudel, Goo Yoon, 2018, Bioorganic & medicinal chemistry.

RalA employs GRK2 and β-arrestins for the filamin A-mediated regulation of trafficking and signaling of dopamine D2 and D3 receptor.

Kyeong-Man Kim, C. Min, M. Zheng, 2016, Biochimica et biophysica acta.

Role of Helix 8 in Dopamine Receptor Signaling

K. Chung, Hyun-Ju Park, Xiaodi Zhao, 2019, Biomolecules & therapeutics.

A novel molecular mechanism involved in the crosstalks between homologous and PKC-mediated heterologous regulatory pathway of dopamine D2 receptor.

Kyeong-Man Kim, Xiaohan Zhang, X. Min, 2020, Biochemical pharmacology.

Clathrin-mediated endocytosis is responsible for the lysosomal degradation of dopamine D3 receptor.

Kyeong-Man Kim, M. Zheng, Xiaohan Zhang, 2016, Biochemical and biophysical research communications.

G Protein-Coupled Receptor Kinase Regulates Dopamine D3 Receptor Signaling By Modulating the Stability of a Receptor/Filamin/β-Arrestin Complex: A Case of Autoreceptor Regulation*

R. Gainetdinov, M. Caron, Kyeong-Man Kim, 2005 .

Activation of Fc Epsilon RI Inhibits the Pyruvate Kinase through Direct Interaction with the Gamma–Chain

Kyeong-Man Kim, M. Oak, H. Cheong, 1999, International Archives of Allergy and Immunology.

Effects of dopaminergic drugs on the mast cell degranulation and nitric oxide generation in RAW 264.7 cells

Kyeong-Man Kim, Il-Woong Seol, Na Youn Kuo, 2004, Archives of pharmacal research.

Design, synthesis, and systematic evaluation of 4-arylpiperazine- and 4-benzylpiperidine napthyl ethers as inhibitors of monoamine neurotransmitters reuptake.

Kyeong-Man Kim, S. Paudel, Goo Yoon, 2018, Bioorganic & medicinal chemistry.

Multiple signaling routes involved in the regulation of adenylyl cyclase and extracellular regulated kinase by dopamine D(2) and D(3) receptors.

Kyeong-Man Kim, H. Kurose, D. Cho, 2013, Pharmacological research.

Triple reuptake inhibitors: Design, synthesis and structure-activity relationship of benzylpiperidine-tetrazoles.

Kyeong-Man Kim, S. Paudel, Goo Yoon, 2017, Bioorganic & medicinal chemistry.

β-Arrestin2 Plays Permissive Roles in the Inhibitory Activities of RGS9-2 on G Protein-Coupled Receptors by Maintaining RGS9-2 in the Open Conformation

Kyeong-Man Kim, D. Cho, C. Min, 2011, Molecular and Cellular Biology.

Multiple regulatory roles of the carboxy terminus of Ste2p a yeast GPCR.

M. Hauser, J. Becker, M. Uddin, 2012, Pharmacological research.

C-Src-mediated phosphorylation of δ-catenin increases its protein stability and the ability of inducing nuclear distribution of β-catenin.

W. Choi, Kyeong-Man Kim, Q. Lu, 2014, Biochimica et biophysica acta.

Design, synthesis and in vitro activity of 1,4-disubstituted piperazines and piperidines as triple reuptake inhibitors.

Kyeong-Man Kim, S. Paudel, Goo Yoon, 2017, Bioorganic & medicinal chemistry.

Novel Regulatory Mechanism of Canonical Wnt Signaling by Dopamine D2 Receptor through Direct Interaction with β-Catenin

K. Kwon, C. Shin, Kyeong-Man Kim, 2011, Molecular Pharmacology.

Structural Requirements for Modulating 4-Benzylpiperidine Carboxamides from Serotonin/Norepinephrine Reuptake Inhibitors to Triple Reuptake Inhibitors

Kyeong-Man Kim, Eunae Kim, S. Paudel, 2021, Biomolecules & therapeutics.

Functional interaction between dopamine receptor subtypes for the regulation of c-fos expression.

Kyeong-Man Kim, M. Oak, Kwang Youl Lee, 2007, Biochemical and biophysical research communications.

Excavation of lead compounds that inhibit mast cell degranulation by combinatorial chemistry and activity-guided

Kyeong-Man Kim, M. Oak, H. Oh, 2004, Archives of pharmacal research.

Design, synthesis and evaluation of bitopic arylpiperazinephenyl-1,2,4-oxadiazoles as preferential dopamine D3 receptor ligands.

Kyeong-Man Kim, S. Cheon, C. Min, 2016, Bioorganic & medicinal chemistry.

Synthesis and evaluation of arylpiperazine-reverse amides as biased dopamine D3 receptor ligands.

Kyeong-Man Kim, S. Paudel, S. Cheon, 2015, Bioorganic & medicinal chemistry.