C. Des Rosiers

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Reversibility of the mitochondrial isocitrate dehydrogenase reaction in the perfused rat liver. Evidence from isotopomer analysis of citric acid cycle intermediates.

H. Brunengraber, C. Des Rosiers, C. A. Fernandez, 1994, The Journal of biological chemistry.

Correction of 13C mass isotopomer distributions for natural stable isotope abundance.

H. Brunengraber, C. Des Rosiers, C. A. Fernandez, 1996, Journal of mass spectrometry : JMS.

Medium-chain Fatty Acids as Metabolic Therapy in Cardiac Disease

C. Des Rosiers, F. Labarthe, R. Gélinas, 2008, Cardiovascular Drugs and Therapy.

Functional evidence for the presence of adenosine A2-receptors in cultured coronary endothelial cells

C. Des Rosiers, S. Nees, 1987, Naunyn-Schmiedeberg's Archives of Pharmacology.

Pyruvate modifies metabolic flux and nutrient sensing during extracorporeal membrane oxygenation in an immature swine model.

N. Isern, C. Des Rosiers, M. Kajimoto, 2015, American journal of physiology. Heart and circulatory physiology.

Myocardial oxidative metabolism and protein synthesis during mechanical circulatory support by extracorporeal membrane oxygenation.

N. Isern, C. Des Rosiers, M. Kajimoto, 2013, American journal of physiology. Heart and circulatory physiology.

Regulation of Malonyl-CoA Concentration and Turnover in the Normal Heart*

H. Brunengraber, C. Des Rosiers, F. David, 2004, Journal of Biological Chemistry.

Pseudoketogenesis in hepatectomized dogs.

C. Cobelli, G. Toffolo, B. Landau, 1990, The American journal of physiology.

Differential modulation of citrate synthesis and release by fatty acids in perfused working rat hearts.

C. Des Rosiers, B. Bouchard, G. Vincent, 2004, American journal of physiology. Heart and circulatory physiology.

Partitioning of pyruvate between oxidation and anaplerosis in swine hearts.

H. Brunengraber, C. Des Rosiers, C. Rosiers, 2000, American journal of physiology. Heart and circulatory physiology.

Metabolic Response of the Immature Right Ventricle to Acute Pressure Overloading

N. Isern, C. Des Rosiers, M. Kajimoto, 2018, Journal of the American Heart Association.

Differential effects of octanoate and heptanoate on myocardial metabolism during extracorporeal membrane oxygenation in an infant swine model.

N. Isern, C. Des Rosiers, M. Kajimoto, 2015, American journal of physiology. Heart and circulatory physiology.

Fatty acid oxidation and its impact on response of spontaneously hypertensive rat hearts to an adrenergic stress: benefits of a medium-chain fatty acid.

C. Des Rosiers, F. Labarthe, W. Stanley, 2005, American journal of physiology. Heart and circulatory physiology.

Metabolic phenotyping of the diseased rat heart using 13C-substrates and ex vivo perfusion in the working mode

C. Des Rosiers, B. Bouchard, M. Khairallah, 2004, Molecular and Cellular Biochemistry.

Probing the link between citrate and malonyl-CoA in perfused rat hearts.

J. Kelleher, H. Brunengraber, C. Des Rosiers, 2002, American journal of physiology. Heart and circulatory physiology.

Effects and metabolism of fumarate in the perfused rat heart. A 13C mass isotopomer study.

C. Des Rosiers, A. Laplante, G. Vincent, 1997, The American journal of physiology.

Metabolic Tracing Using Stable Isotope-Labeled Substrates and Mass Spectrometry in the Perfused Mouse Heart.

C. Des Rosiers, F. Vaillant, R. Gélinas, 2015, Methods in enzymology.

First characterization of glucose flux through the hexosamine biosynthesis pathway (HBP) in ex vivo mouse heart

C. Des Rosiers, J. Chatham, W. Zhu, 2020, The Journal of Biological Chemistry.

Cyclic GMP signaling in cardiomyocytes modulates fatty acid trafficking and prevents triglyceride accumulation.

C. Des Rosiers, C. Deschepper, G. Lopaschuk, 2008, Journal of molecular and cellular cardiology.

Circulating acylcarnitine profile in human heart failure: a surrogate of fatty acid metabolic dysregulation in mitochondria and beyond.

P. A. Crawford, A. Ducharme, J. Tardif, 2017, American journal of physiology. Heart and circulatory physiology.

Protecting the heart through MK2 modulation, toward a role in diabetic cardiomyopathy and lipid metabolism.

C. Des Rosiers, B. Allen, L. Coderre, 2017, Biochimica et biophysica acta. Molecular basis of disease.

Metabolism and acetylation contribute to leucine-mediated inhibition of cardiac glucose uptake.

J. Auquier, L. Bertrand, A. Ginion, 2017, American journal of physiology. Heart and circulatory physiology.

Treatment with Docosahexaenoic Acid, but Not Eicosapentaenoic Acid, Delays Ca2+-Induced Mitochondria Permeability Transition in Normal and Hypertrophied Myocardium

K. O’Shea, C. Des Rosiers, W. Stanley, 2010, Journal of Pharmacology and Experimental Therapeutics.

Decreased cardiac mitochondrial NADP+-isocitrate dehydrogenase activity and expression: a marker of oxidative stress in hypertrophy development.

C. Des Rosiers, B. Comte, M. Benderdour, 2004, American journal of physiology. Heart and circulatory physiology.

A single Mediterranean meal does not impair postprandial flow-mediated dilatation in healthy men with subclinical metabolic dysregulations.

J. Tardif, S. Lacroix, C. Des Rosiers, 2016, Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme.

mTORC1 is required for expression of LRPPRC and cytochrome-c oxidase but not HIF-1α in Leigh syndrome French Canadian type patient fibroblasts.

C. Laprise, C. Des Rosiers, J. Tardif, 2019, American journal of physiology. Cell physiology.

Reducing 14-3-3ζ expression influences adipocyte maturity and impairs function.

C. Des Rosiers, G. E. Lim, Isabelle Robillard Frayne, 2020, American journal of physiology. Endocrinology and metabolism.

Acute Regulation of Cardiac Metabolism by the Hexosamine Biosynthesis Pathway and Protein O-GlcNAcylation

C. Des Rosiers, J. Chatham, A. Onay-Beşikci, 2011, PloS one.

Rates of gluconeogenesis and citric acid cycle in perfused livers, assessed from the mass spectrometric assay of the 13C labeling pattern of glutamate.

H. Brunengraber, C. Des Rosiers, F. David, 1993, The Journal of biological chemistry.

Metabolic effects of glutamine on the heart: anaplerosis versus the hexosamine biosynthetic pathway.

V. Dolinsky, J. Dyck, C. Des Rosiers, 2013, Journal of molecular and cellular cardiology.

NADPH oxidase activation by hyperglycaemia in cardiomyocytes is independent of glucose metabolism but requires SGLT1.

L. Bertrand, C. Beauloye, A. Ginion, 2011, Cardiovascular research.

Metabolic and signaling alterations in dystrophin-deficient hearts precede overt cardiomyopathy.

J. Dyck, C. Des Rosiers, M. Young, 2007, Journal of molecular and cellular cardiology.

Mouse strain differences in metabolic fluxes and function of ex vivo working hearts.

C. Des Rosiers, F. Vaillant, É. Thorin, 2014, American journal of physiology. Heart and circulatory physiology.

Ivabradine reduces heart rate while preserving metabolic fluxes and energy status of healthy normoxic working hearts.

J. Tardif, C. Des Rosiers, R. Brownsey, 2011, American journal of physiology. Heart and circulatory physiology.

Post-translational modifications, a key process in CD36 function: lessons from the spontaneously hypertensive rat heart.

V. Dolinsky, J. Dyck, C. Des Rosiers, 2011, Journal of molecular and cellular cardiology.

ω-3 Polyunsaturated fatty acids prevent pressure overload-induced ventricular dilation and decrease in mitochondrial enzymes despite no change in adiponectin

K. Walsh, K. O’Shea, C. Des Rosiers, 2010, Lipids in Health and Disease.

Alterations in mitochondrial function as a harbinger of cardiomyopathy: lessons from the dystrophic heart.

C. Des Rosiers, C. Deschepper, Y. Burelle, 2010, Journal of molecular and cellular cardiology.

Alterations in carbohydrate metabolism and its regulation in PPARalpha null mouse hearts.

C. Des Rosiers, M. Young, F. Labarthe, 2008, American journal of physiology. Heart and circulatory physiology.

Sildenafil and cardiomyocyte-specific cGMP signaling prevent cardiomyopathic changes associated with dystrophin deficiency

C. Des Rosiers, C. Rosiers, C. Deschepper, 2008, Proceedings of the National Academy of Sciences.

Peroxisomal Fatty Acid Oxidation Is a Substantial Source of the Acetyl Moiety of Malonyl-CoA in Rat Heart*

C. Hoppel, H. Brunengraber, C. Des Rosiers, 2004, Journal of Biological Chemistry.

Assay of the concentration and 13C-isotopic enrichment of malonyl-coenzyme A by gas chromatography-mass spectrometry.

H. Brunengraber, C. Des Rosiers, F. David, 2001, Analytical biochemistry.

Assessing the Reversibility of the Anaplerotic Reactions of the Propionyl-CoA Pathway in Heart and Liver*

C. Hoppel, H. Brunengraber, C. Des Rosiers, 2003, Journal of Biological Chemistry.

Instantaneous analysis of aldehydes in biological fluids using a spray interface coupled to a mass spectrometer.

C. Des Rosiers, F. St-Germain, B. Vachon, 1997, Free radical biology & medicine.

A high omega-3 fatty acid diet rapidly changes the lipid composition of cardiac tissue and results in cardioprotection.

G. Rousseau, C. Des Rosiers, C. Daneault, 2018, Canadian journal of physiology and pharmacology.

Gas chromatographic-mass spectrometric assay of tissue malondialdehyde, 4-hydroxynonenal, and other aldehydes after their reduction to stable alcohols.

C. Des Rosiers, A. Kumar, M. Boily, 1993, Analytical biochemistry.

Marine n3 polyunsaturated fatty acids enhance resistance to mitochondrial permeability transition in heart failure but do not improve survival.

K. O’Shea, H. Sabbah, C. Des Rosiers, 2013, American journal of physiology. Heart and circulatory physiology.

Dietary omega-3 fatty acids alter cardiac mitochondrial phospholipid composition and delay Ca2+-induced permeability transition.

G. Fiskum, T. Kristian, R. Murphy, 2009, Journal of molecular and cellular cardiology.

Propofol Compared with Isoflurane Inhibits Mitochondrial Metabolism in Immature Swine Cerebral Cortex

N. Isern, C. Des Rosiers, E. Kayser, 2014, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Mitochondrial Vulnerability and Increased Susceptibility to Nutrient-Induced Cytotoxicity in Fibroblasts from Leigh Syndrome French Canadian Patients

G. Boucher, C. Des Rosiers, Y. Burelle, 2015, PloS one.

Increased cardiac fatty acid oxidation in a mouse model with decreased malonyl-CoA sensitivity of CPT1B

J. Auwerx, C. Argmann, S. Denis, 2018, Cardiovascular research.

Effects of N-acetylcysteine in the rat heart reperfused after low-flow ischemia: evidence for a direct scavenging of hydroxyl radicals and a nitric oxide-dependent increase in coronary flow.

C. Des Rosiers, C. Rosiers, J. Brunet, 1995, Free radical biology & medicine.

Identification of Circulating Endocan-1 and Ether Phospholipids as Biomarkers for Complications in Thalassemia Patients

N. Chattipakorn, S. Chattipakorn, G. Sweeney, 2021, Metabolites.

Nonhomogeneous labeling of liver mitochondrial acetyl-CoA.

H. Brunengraber, C. Des Rosiers, F. David, 1991, The Journal of biological chemistry.

Interference of 3-hydroxyisobutyrate with measurements of ketone body concentration and isotopic enrichment by gas chromatography-mass spectrometry.

H. Brunengraber, C. Des Rosiers, F. David, 1988, Analytical biochemistry.

Dystrophin‐deficient cardiomyocytes are abnormally vulnerable to mechanical stress‐induced contractile failure and injury

A. Comtois, C. Des Rosiers, B. Petrof, 2001, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Adaptive optimization of the OXPHOS assembly line partially compensates lrpprc-dependent mitochondrial translation defects in mice

C. Des Rosiers, C. Daneault, Y. Burelle, 2021, Communications biology.

Humoral responses to the measles, mumps and rubella vaccine are impaired in Leigh Syndrome French Canadian patients

C. Laprise, C. Des Rosiers, C. Morin, 2020, PloS one.

Long-Chain Acylcarnitines and Monounsaturated Fatty Acids Discriminate Heart Failure Patients According to Pulmonary Hypertension Status

A. Ducharme, J. Tardif, C. Des Rosiers, 2021, Metabolites.

Circulating 4-hydroxynonenal-protein thioether adducts assessed by gas chromatography-mass spectrometry are increased with disease progression and aging in spontaneously hypertensive rats.

J. Tardif, C. Des Rosiers, Bertrand Bouchard, 2006, Free radical biology & medicine.

Prolonged QT interval and lipid alterations beyond β-oxidation in very long-chain acyl-CoA dehydrogenase null mouse hearts.

C. Des Rosiers, C. Daneault, F. Labarthe, 2011, American journal of physiology. Heart and circulatory physiology.

A comparison between NMR and GCMS 13C-isotopomer analysis in cardiac metabolism

C. Des Rosiers, J. Chatham, Bertrand Bouchard, 2001, Molecular and Cellular Biochemistry.

Stress-induced opening of the permeability transition pore in the dystrophin-deficient heart is attenuated by acute treatment with sildenafil.

C. Bourcier-Lucas, C. Des Rosiers, F. Daussin, 2011, American journal of physiology. Heart and circulatory physiology.

Dynamic responses of the glutathione system to acute oxidative stress in dystrophic mouse (mdx) muscles.

L. Lands, C. Des Rosiers, Roy W R Dudley, 2006, American journal of physiology. Regulatory, integrative and comparative physiology.

Very Long-Chain Unsaturated Sphingolipids Mediate Oleate-Induced Rat β-Cell Proliferation

S. Summers, V. Poitout, C. Des Rosiers, 2021, bioRxiv.

Quantitative gas chromatographic-mass spectrometric assay of 4-hydroxynonenal bound to thiol proteins in ischemic/reperfused rat hearts.

C. Des Rosiers, B. Comte, M. Véronneau, 2002, Free radical biology & medicine.

Metabolic Response to Stress by the Immature Right Ventricle Exposed to Chronic Pressure Overload

N. Isern, C. Des Rosiers, M. Kajimoto, 2019, Journal of the American Heart Association.

Mitochondrial Pyruvate Carriers are Required for Myocardial Stress Adaptation

Paul V. Taufalele, R. Weiss, E. Lewandowski, 2020, Nature Metabolism.

Pseudoketogenesis in the perfused rat heart.

B. Landau, H. Brunengraber, C. Des Rosiers, 1988, The Journal of biological chemistry.

Protein O‐GlcNAcylation levels are regulated independently of dietary intake in a tissue and time‐specific manner during rat postnatal development

D. Vertommen, L. Bertrand, T. Issad, 2020, Acta physiologica.

Metabolism of R-beta-hydroxypentanoate and of beta-ketopentanoate in conscious dogs.

H. Brunengraber, C. Des Rosiers, C. A. Fernandez, 1995, The American journal of physiology.

Assay of blood and tissue oxaloacetate and alpha-ketoglutarate by isotope dilution gas chromatography-mass spectrometry.

C. Des Rosiers, B. Comte, A. Laplante, 1995, Analytical biochemistry.

Interpretation of isotopomer patterns in tracing glycogen synthesis and glucose recycling using [13C6]glucose.

B. Landau, H. Brunengraber, C. Des Rosiers, 1990, The American journal of physiology.

Why publish in the American Journal of Physiology-Heart and Circulatory Physiology?

Steven P Jones, D. Kass, D. O'Leary, 2017, American journal of physiology. Heart and circulatory physiology.

Heart Rate Reduction by Ivabradine Reduces Diastolic Dysfunction and Cardiac Fibrosis

J. Tardif, C. Des Rosiers, É. Rhéaume, 2011, Cardiology.

Cardiac anaplerosis in health and disease: food for thought.

S. Lloyd, C. Des Rosiers, J. Chatham, 2011, Cardiovascular research.

Acute hibernation decreases myocardial pyruvate carboxylation and citrate release.

M. Chandler, H. Brunengraber, C. Des Rosiers, 2001, American journal of physiology. Heart and circulatory physiology.

Purine metabolism in cultured aortic and coronary endothelial cells.

C. Des Rosiers, S. Nees, E. Gerlach, 1989, Biochemistry and cell biology = Biochimie et biologie cellulaire.

Dosimetric analysis and clinical implementation of 6 MV X-ray radiosurgery beam.

C. Des Rosiers, W. Bloomer, K. Parthasaradhi, 1997, Medical dosimetry : official journal of the American Association of Medical Dosimetrists.

Metabolism of S-3-hydroxybutyrate in the perfused rat liver.

H. Brunengraber, C. Des Rosiers, B. Lincoln, 1987, Archives of biochemistry and biophysics.

Quantitation of 1,3-butanediol and its acidic metabolites by gas chromatography-mass spectrometry.

H. Brunengraber, C. Des Rosiers, J. Montgomery, 1990, Analytical biochemistry.

A Metabolic Signature of Mitochondrial Dysfunction Revealed through a Monogenic Form of Leigh Syndrome

J. Rioux, V. Mootha, C. Laprise, 2015, Cell reports.

Muscle-Specific Lipid Hydrolysis Prolongs Lifespan through Global Lipidomic Remodeling.

C. Des Rosiers, S. Schmeisser, R. Roy, 2019, Cell reports.

Loss of hepatic LRPPRC alters mitochondrial bioenergetics, regulation of permeability transition and trans-membrane ROS diffusion

J. Rioux, E. Shoubridge, C. Des Rosiers, 2017, Human molecular genetics.

Serum Analyte Profiles Associated With Crohn's Disease and Disease Location.

Judy H. Cho, Claire L. Simpson, J. Rioux, 2021, Inflammatory bowel diseases.

Serum Lipidomic Screen Identifies Key Metabolites, Pathways, and Disease Classifiers in Crohn's Disease.

Judy H. Cho, J. Rioux, M. Silverberg, 2023, Inflammatory bowel diseases.

SLC25A46 is required for mitochondrial lipid homeostasis and cristae maintenance and is responsible for Leigh syndrome

E. Shoubridge, A. Gingras, H. McBride, 2016, EMBO molecular medicine.

Mitochondrial dysfunction and lipid accumulation in the human diaphragm during mechanical ventilation.

D. Turnbull, S. Jaber, S. Matecki, 2012, American journal of respiratory and critical care medicine.

Oxidative Stress and Myocardial Gene Alterations Associated with Doxorubicin-Induced Cardiotoxicity in Rats Persist for 2 Months after Treatment Cessation

L. Rochette, Y. Cottin, C. Richard, 2011, Journal of Pharmacology and Experimental Therapeutics.

Assessing Cardiac Metabolism: A Scientific Statement From the American Heart Association.

Thomas J. Wang, S. Neubauer, R. Gropler, 2016, Circulation research.

Circulating levels of linoleic acid and HDL-cholesterol are major determinants of 4-hydroxynonenal protein adducts in patients with heart failure

A. Ducharme, E. Levy, J. Tardif, 2013, Redox biology.

High intake of saturated fat, but not polyunsaturated fat, improves survival in heart failure despite persistent mitochondrial defects.

K. O’Shea, H. Sabbah, C. Des Rosiers, 2012, Cardiovascular research.

Past history of obesity triggers persistent epigenetic changes in innate immunity and exacerbates neuroinflammation

T. Langmann, C. Des Rosiers, C. Daneault, 2023, Science.

Cardiac Mitochondrial NADP+-isocitrate Dehydrogenase Is Inactivated through 4-Hydroxynonenal Adduct Formation

C. Des Rosiers, B. Comte, M. Benderdour, 2003, Journal of Biological Chemistry.

Applications of mass isotopomer analysis to nutrition research.

J K Kelleher, J. Kelleher, H. Brunengraber, 1997, Annual review of nutrition.

PCSK9 Induces CD36 Degradation and Affects Long-Chain Fatty Acid Uptake and Triglyceride Metabolism in Adipocytes and in Mouse Liver

C. Des Rosiers, G. Mayer, H. Ong, 2015, Arteriosclerosis, thrombosis, and vascular biology.

Purine synthesis de novo and its regulation in rat hepatocytes.

C. Des Rosiers, M. Lalanne, J. Willemot, 1980, Canadian journal of biochemistry.

Selective cerebral perfusion prevents abnormalities in glutamate cycling and neuronal apoptosis in a model of infant deep hypothermic circulatory arrest and reperfusion

N. Isern, C. Des Rosiers, M. Kajimoto, 2016, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

A critical perspective of the use of (13)C-isotopomer analysis by GCMS and NMR as applied to cardiac metabolism.

S. Lloyd, C. Des Rosiers, B. Comte, 2004, Metabolic engineering.

Triiodothyronine Facilitates Weaning From Extracorporeal Membrane Oxygenation by Improved Mitochondrial Substrate Utilization

N. Isern, C. Des Rosiers, M. Kajimoto, 2014, Journal of the American Heart Association.

Applications of metabolomics and proteomics to the mdx mouse model of Duchenne muscular dystrophy: lessons from downstream of the transcriptome

J. Griffin, C. Des Rosiers, 2009, Genome Medicine.

Validation of fatty acid intakes estimated by a food frequency questionnaire using erythrocyte fatty acid profiling in the Montreal Heart Institute Biobank.

G. Lettre, J. Tardif, V. Turcot, 2015, Journal of human nutrition and dietetics : the official journal of the British Dietetic Association.

Heart rate-associated mechanical stress impairs carotid but not cerebral artery compliance in dyslipidemic atherosclerotic mice.

Jean-Claude Tardif, Eric Thorin, Virginie Bolduc, 2011, American journal of physiology. Heart and circulatory physiology.

Comprehensive and Reproducible Untargeted Lipidomic Workflow Using LC-QTOF Validated for Human Plasma Analysis.

J. Rioux, J. Tardif, G. Boucher, 2018, Journal of proteome research.

Adaptive optimization of the OXPHOS assembly line partially compensates lrpprc-dependent mitochondrial translation defects in mice

J. Rioux, E. Shoubridge, C. Laprise, 2021, Communications Biology.

AMPK activation counteracts cardiac hypertrophy by reducing O-GlcNAcylation

B. Viollet, J. Balligand, L. Bertrand, 2018, Nature Communications.

Evidence of separate pathways for lactate uptake and release by the perfused rat heart.

C. Des Rosiers, C. Rosiers, J. Chatham, 2001, American journal of physiology. Endocrinology and metabolism.

Profiling substrate fluxes in the isolated working mouse heart using 13C-labeled substrates: focusing on the origin and fate of pyruvate and citrate carbons.

C. Des Rosiers, F. Labarthe, Basil J Petrof, 2004, American journal of physiology. Heart and circulatory physiology.

Plasma metabolomics identify hydroxyproline as a potential player in the pathophysiogy of HFpEF

L. Bertrand, C. Beauloye, A. Pouleur, 2022, Archives of Cardiovascular Diseases Supplements.

Ivabradine and metoprolol differentially affect cardiac glucose metabolism despite similar heart rate reduction in a mouse model of dyslipidemia.

J. Tardif, C. Des Rosiers, D. Lachance, 2016, American journal of physiology. Heart and circulatory physiology.

Biosynthesis and characterization of 3-hydroxyalkan-2-ones and 2,3-alkanediols: potential products of aldehyde metabolism.

H. Brunengraber, C. Des Rosiers, J. Montgomery, 1992, Biological mass spectrometry.

MK2 Deletion in Mice Prevents Diabetes-Induced Perturbations in Lipid Metabolism and Cardiac Dysfunction

M. Gaestel, A. Carpentier, C. Des Rosiers, 2015, Diabetes.

Resveratrol Prevents the Prohypertrophic Effects of Oxidative Stress on LKB1

Anita Y. M. Chan, V. Dolinsky, P. Light, 2009, Circulation.

Gene-metabolite annotation with shortest reactional distance enhances metabolite genome-wide association studies results

J. Rioux, G. Lettre, A. Ashley-Koch, 2023, bioRxiv.

Dietary supplementation with docosahexaenoic acid, but not eicosapentaenoic acid, dramatically alters cardiac mitochondrial phospholipid fatty acid composition and prevents permeability transition.

Gary Fiskum, William C Stanley, Peter A Hecker, 2010, Biochimica et biophysica acta.

One-stage hepatectomy in the dog.

H. Brunengraber, C. Des Rosiers, P. Daloze, 1990, The Journal of surgical research.

Myocardial phenotyping using isotopomer analysis of metabolic fluxes.

C. Des Rosiers, J. Chatham, 2005, Biochemical Society transactions.

Reverse flux through cardiac NADP(+)-isocitrate dehydrogenase under normoxia and ischemia.

C. Des Rosiers, B. Comte, M. Benderdour, 2002, American journal of physiology. Heart and circulatory physiology.

Impact of obesity on day‐night differences in cardiac metabolism

S. Mia, S. Frank, C. Des Rosiers, 2021, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Biomarker-guided stratification of autoimmune patients for biologic therapy.

J. Rioux, M. Levings, C. Des Rosiers, 2017, Current opinion in immunology.

Calorie Restriction Prevents Hypertension and Cardiac Hypertrophy in the Spontaneously Hypertensive Rat

V. Dolinsky, K. Walsh, S. Davidge, 2010, Hypertension.

Abnormal in vivo myocardial energy substrate uptake in diet-induced type 2 diabetic cardiomyopathy in rats.

E. Croteau, M. Bentourkia, R. Lecomte, 2010, American journal of physiology. Endocrinology and metabolism.

Probing pyruvate metabolism in normal and mutant fibroblast cell lines using 13C-labeled mass isotopomer analysis and mass spectrometry.

C. Des Rosiers, P. Pencharz, B. Robinson, 2009, Molecular genetics and metabolism.

Publisher Correction: Mitochondrial pyruvate carriers are required for myocardial stress adaptation

Paul V. Taufalele, R. Weiss, E. Lewandowski, 2020, Nature Metabolism.

AMPK activation counteracts cardiac hypertrophy by reducing O-GlcNAcylation

B. Viollet, J. Balligand, L. Bertrand, 2018, Nature Communications.

A high omega-3 fatty acid diet rapidly changes the lipid composition of cardiac tissue and results in cardioprotection.

G. Rousseau, C. Des Rosiers, C. Daneault, 2018, Canadian journal of physiology and pharmacology.

Prolonged QT interval and lipid alterations beyond β-oxidation in very long-chain acyl-CoA dehydrogenase null mouse hearts.

C. Des Rosiers, C. Daneault, F. Labarthe, 2011, American journal of physiology. Heart and circulatory physiology.

Ivabradine and metoprolol differentially affect cardiac glucose metabolism despite similar heart rate reduction in a mouse model of dyslipidemia.

J. Tardif, C. Des Rosiers, D. Lachance, 2016, American journal of physiology. Heart and circulatory physiology.

Metabolism and acetylation contribute to leucine-mediated inhibition of cardiac glucose uptake.

J. Auquier, L. Bertrand, A. Ginion, 2017, American journal of physiology. Heart and circulatory physiology.

Circulating acylcarnitine profile in human heart failure: a surrogate of fatty acid metabolic dysregulation in mitochondria and beyond.

A. Ducharme, J. Tardif, C. Des Rosiers, 2017, American journal of physiology. Heart and circulatory physiology.

Perturbations in lipid metabolism and gut microbiota composition precede cardiac dysfunction in a mouse model of thalassemia.

C. Des Rosiers, C. Fillebeen, K. Pantopoulos, 2023, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Acyloin production from aldehydes in the perfused rat heart: the potential role of pyruvate dehydrogenase.

Stéphane Huot, C. Des Rosiers, J. Montgomery, 1993, The Biochemical journal.

Variable glycation of serum proteins in patients with diabetes mellitus.

C. Des Rosiers, R. Comtois, M. Couturier, 1997, Clinical and investigative medicine. Medecine clinique et experimentale.

Pyruvate modifies metabolic flux and nutrient sensing during extracorporeal membrane oxygenation in an immature swine model.

N. Isern, C. Des Rosiers, M. Kajimoto, 2015, American journal of physiology. Heart and circulatory physiology.

A NRF2/β3-adrenoreceptor axis drives a sustained antioxidant and metabolic rewiring through the pentose-phosphate pathway to alleviate cardiac stress

J. Balligand, C. Des Rosiers, C. Bouzin, 2023, bioRxiv.