I. Miyawaki

发表

Distinct synaptic and related transcriptional abnormalities in neonatal, childhood and mature autism model of primate: implications for early-age therapeutic intervention

T. Kurotani, J. Noguchi, T. Minamimoto, 2020, bioRxiv.

Evaluation of ovarian toxicity of mono-(2-ethylhexyl) phthalate (MEHP) using cultured rat ovarian follicles.

T. Miyano, I. Miyawaki, H. Inada, 2012, The Journal of toxicological sciences.

Applicability of the Øie‐Tozer model to predict three types of distribution volume (Vd) in humans: Vd in central compartment, Vd at steady state, and Vd at beta phase

I. Miyawaki, Y. Ishii, M. Yahata, 2020, Biopharmaceutics & drug disposition.

Application of zebrafish to safety evaluation in drug discovery

I. Miyawaki, 2020, Journal of toxicologic pathology.

Investigation of the role and quantitative impact of breast cancer resistance protein on drug distribution into brain and CSF in rats

M. Takano, I. Miyawaki, Koji Umemura, 2021, Drug Metabolism and Pharmacokinetics.

Evaluation of ovarian toxicity of sodium valproate (VPA) using cultured rat ovarian follicles.

T. Miyano, I. Miyawaki, H. Inada, 2012, The Journal of toxicological sciences.

Oral administration of drugs with hypersensitivity potential induces germinal center hyperplasia in secondary lymphoid organ/tissue in Brown Norway rats, and this histological lesion is a promising candidate as a predictive biomarker for drug hypersensitivity occurrence in humans.

I. Miyawaki, J. Kimura, H. Funabashi, 2013, Toxicology and applied pharmacology.

Telemetered common marmosets is useful for the assessment of electrocardiogram parameters changes induced by multiple cardiac ion channel inhibitors.

E. Hinoi, I. Miyawaki, T. Tsubouchi, 2019, The Journal of toxicological sciences.

The effects of clobazam treatment in rats on the expression of genes and proteins encoding glucronosyltransferase 1A/2B (UGT1A/2B) and multidrug resistance-associated protein-2 (MRP2), and development of thyroid follicular cell hypertrophy.

I. Miyawaki, H. Inada, T. Kunimatsu, 2012, Toxicology and applied pharmacology.

Establishment of a novel experimental protocol for drug-induced seizure liability screening based on a locomotor activity assay in zebrafish.

I. Miyawaki, Akihito Yamashita, H. Funabashi, 2014, The Journal of toxicological sciences.

Toxicological approach for elucidation of clobazam-induced hepatomegaly in male rats.

T. Seki, I. Miyawaki, H. Inada, 2011, Regulatory toxicology and pharmacology : RTP.

Detection of fenoldopam-induced arteritis in rats using ex vivo / in vivo MRI

A. Nakae, I. Miyawaki, Kazuhiro Chihara, 2022, Toxicology reports.

Biosynthesis of Poly(3-Hydroxyalkanoic Acid) Copolymer from CO(inf2) in Pseudomonas acidophila through Introduction of the DNA Fragment Responsible for Chemolithoautotrophic Growth of Alcaligenes hydrogenophilus

M. Kawase, K. Yagi, I. Miyawaki, 1996, Applied and environmental microbiology.

hydrogenophilus.ophic Growth of Alcaligenes Fragment Responsible for acidophila through Introduction of the DNA Copolymer from CO(inf2) in Pseudomonas Biosynthesis of Poly(3-Hydroxyalkanoic Acid)

M. Kawase, I. Miyawaki, I. Maeda, 2013 .

Imbalance of circuit plasticity and consolidation in autism model marmosets is adjusted by oxytocin administration

T. Yamamori, A. Watakabe, J. Noguchi, 2022, bioRxiv.

Metabolic profiling of urine and blood plasma in rat models of drug addiction on the basis of morphine, methamphetamine, and cocaine-induced conditioned place preference

E. Fukusaki, T. Bamba, Koichi Suzuki, 2014, Analytical and Bioanalytical Chemistry.

Functional and molecular characterization of a non-human primate model of autism spectrum disorder shows similarity with the human disease

T. Kurotani, J. Noguchi, T. Minamimoto, 2021, Nature Communications.

Influences of methamphetamine-induced acute intoxication on urinary and plasma metabolic profiles in the rat.

E. Fukusaki, T. Bamba, I. Miyawaki, 2011, Toxicology.

Mechanism of clobazam-induced thyroidal oncogenesis in male rats.

I. Miyawaki, H. Funabashi, M. Yasuba, 2003, Toxicology letters.

[Drug dependence study].

I. Miyawaki, 2007, Nihon yakurigaku zasshi. Folia pharmacologica Japonica.

Clozapine-specific proliferative response of peripheral blood-derived mononuclear cells in Japanese patients with clozapine-induced agranulocytosis

M. Ikeda, N. Iwata, I. Miyawaki, 2022, Journal of psychopharmacology.

Multiplatform metabolomic analysis of the R6/2 mouse model of Huntington’s disease

I. Miyawaki, Masayo Hashimoto, K. Miyoshi, 2021, FEBS open bio.

Use of an alternating current amplifier when recording the ERG c-wave to evaluate the function of retinal pigment epithelial cells in rats

I. Miyawaki, H. Inada, Naohisa Umeya, 2022, Documenta Ophthalmologica.

Increased susceptibility to oxidative stress-induced toxicological evaluation by genetically modified nrf2a-deficient zebrafish.

Y. Nishimura, I. Miyawaki, Akihito Yamashita, 2019, Journal of pharmacological and toxicological methods.

Automatic switching valve system to minimize variation of liquid chromatography-tandem mass spectrometry-based chiral amino acid profiling.

E. Fukusaki, I. Miyawaki, Kenichi Watanabe, 2019, Journal of bioscience and bioengineering.

Evaluation of in vivo MRI for detecting midodrine-induced arteritis in rats

A. Nakae, I. Miyawaki, Kazuhiro Chihara, 2023, Toxicology Reports.

Developmental expression profiles of axon guidance signaling and the immune system in the marmoset cortex: potential molecular mechanisms of pruning of dendritic spines during primate synapse formation in late infancy and prepuberty (I).

Kayo Sumida, Koichi Saito, Noritaka Ichinohe, 2014, Biochemical and biophysical research communications.

Abnormal axon guidance signals and reduced interhemispheric connection via anterior commissure in neonates of marmoset ASD model

Koichi Saito, Ichio Aoki, Koki Mimura, 2019, NeuroImage.

Availability of multistep light stimulus method for evaluation of visual dysfunctions.

I. Miyawaki, Keigo Ikeda, M. Kamada, 2019, Journal of pharmacological and toxicological methods.

Effects of microsampling on toxicity assessment of hematotoxic compounds in a general toxicity study in rats.

I. Miyawaki, H. Inada, Kazuhiro Chihara, 2022, The Journal of toxicological sciences.

Usefulness of Simultaneous Measurement of Plasma Steroids, Including Precursors, for the Evaluation of Drug Effects on Adrenal Steroidogenesis in Rats

I. Miyawaki, Akihito Yamashita, Toru Yamada, 2017, Toxicologic pathology.

Changes in plasma concentrations of corticosterone and its precursors after ketoconazole administration in rats: An application of simultaneous measurement of multiple steroids using LC-MS/MS.

I. Miyawaki, Akihito Yamashita, H. Funabashi, 2016, Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie.

Physiological and drug-induced changes in blood levels of adrenal steroids and their precursors in cynomolgus monkeys: An application of steroid profiling by LC-MS/MS for evaluation of the adrenal toxicity.

I. Miyawaki, Akihito Yamashita, Toru Yamada, 2019, The Journal of toxicological sciences.

Dose- and time-dependent changes in blood and adrenal levels of multiple steroids in rats after administration of ketoconazole with or without ACTH.

I. Miyawaki, Akihito Yamashita, I. Matsumoto, 2019, The Journal of toxicological sciences.

Comparison of 1H-magnetic resonance spectroscopy and blood biochemistry as methods for monitoring non-diffuse hepatic steatosis in a rat model

A. Nakae, I. Miyawaki, Kazuhiro Chihara, 2023, Toxicology reports.

Estimation of contribution of CYP2D6 to tipepidine metabolism in humans and prolongation of the half-life of tipepidine by combination use with a CYP2D6 inhibitor in chimeric mice with humanised liver

I. Miyawaki, T. Fukami, M. Nakajima, 2023, Xenobiotica; the fate of foreign compounds in biological systems.

Altered projection-specific synaptic remodeling and its modification by oxytocin in an idiopathic autism marmoset model

T. Yamamori, A. Watakabe, J. Noguchi, 2023, bioRxiv.