Y. Tung

发表

Six new loci associated with body mass index highlight a neuronal influence on body weight regulation

Christian Gieger, Thomas Meitinger, Inês Barroso, 2009, Nature Genetics.

Subcellular Profiling Reveals Distinct and Developmentally Regulated Repertoire of Growth Cone mRNAs

Michael Piper, J. Fawcett, C. Holt, 2010, The Journal of Neuroscience.

Genetic Defects in Human Pericentrin Are Associated With Severe Insulin Resistance and Diabetes

S. O’Rahilly, M. O’Driscoll, J. Nolan, 2011, Diabetes.

Leptin regulates peripheral lipid metabolism primarily through central effects on food intake.

S. O’Rahilly, J. Griffin, I. Farooqi, 2008, Endocrinology.

Pro-opiomelanocortin modulates the thermogenic and physical activity responses to high-fat feeding and markedly influences dietary fat preference.

S. O’Rahilly, Y. Tung, A. Coll, 2007, Endocrinology.

Differential effects of α-, β- and γ2-melanocyte-stimulating hormones on hypothalamic neuronal activation and feeding in the fasted rat

S. O’Rahilly, Y. Tung, S. Dickson, 2001, Neuroscience.

A truncation mutation in TBC1D4 in a family with acanthosis nigricans and postprandial hyperinsulinemia

S. O’Rahilly, G. Lienhard, I. Barroso, 2009, Proceedings of the National Academy of Sciences.

Obesity-associated gene TMEM18 has a role in the central control of appetite and body weight regulation

S. O’Rahilly, V. Saudek, G. Yeo, 2017, Proceedings of the National Academy of Sciences.

Pro-opiomelanocortin (POMC)-derived peptides and the regulation of energy homeostasis

Y. Tung, A. Coll, Y. C. Tung, 2009, Molecular and Cellular Endocrinology.

Trim28 Haploinsufficiency Triggers Bi-stable Epigenetic Obesity

M. Surani, S. O’Rahilly, T. Jenuwein, 2016, Cell.

Activation of the hypothalamic–pituitary–adrenal axis by exogenous and endogenous GDF15

S. O’Rahilly, M. Clatworthy, G. Yeo, 2021, Proceedings of the National Academy of Sciences.

Constitutional Thinness: tALKing the tALK or wALKing the wALK?

S. O’Rahilly, Y. Tung, Y. C. Tung, 2020, Cell metabolism.

Peripheral administration of the N-terminal pro-opiomelanocortin fragment 1-28 to Pomc-/- mice reduces food intake and weight but does not affect adrenal growth or corticosterone production.

S. O’Rahilly, F. Beuschlein, M. Fassnacht, 2006, The Journal of endocrinology.

Actions of leptin on growth hormone secretagogue-responsive neurones in the rat hypothalamic arcuate nucleus recorded in vitro.

Y. Tung, S. Dickson, A. K. Hewson, 2001 .

A comparative study of the central effects of specific proopiomelancortin (POMC)-derived melanocortin peptides on food intake and body weight in pomc null mice.

S. O’Rahilly, Y. Tung, A. Coll, 2006, Endocrinology.

Differential effects of alpha-, beta- and gamma(2)-melanocyte-stimulating hormones on hypothalamic neuronal activation and feeding in the fasted rat.

S. O’Rahilly, Y. Tung, S. Dickson, 2001, Neuroscience.

Obesity and FTO: Changing Focus at a Complex Locus.

S. O’Rahilly, G. Yeo, Y. Tung, 2014, Cell metabolism.

GDF15 mediates the effects of metformin on body weight and energy balance

S. O’Rahilly, N. Wareham, G. Yeo, 2019, Nature.

A multicomponent screen for feeding behaviour and nutritional status in Drosophila to interrogate mammalian appetite-related genes

S. O’Rahilly, G. Yeo, Y. Tung, 2020, Molecular metabolism.

Adult Onset Global Loss of the Fto Gene Alters Body Composition and Metabolism in the Mouse

F. Ashcroft, S. Wells, R. Cox, 2013, PLoS genetics.

The Obesity-Associated FTO Gene Encodes a 2-Oxoglutarate-Dependent Nucleic Acid Demethylase

Chris P. Ponting, Christopher J. Schofield, Patrik Rorsman, 2007, Science.

Hyperphagia, Severe Obesity, Impaired Cognitive Function, and Hyperactivity Associated With Functional Loss of One Copy of the Brain-Derived Neurotrophic Factor (BDNF) Gene

J. Hodges, S. O’Rahilly, G. Yeo, 2006, Diabetes.

Hypothalamic-Specific Manipulation of Fto, the Ortholog of the Human Obesity Gene FTO, Affects Food Intake in Rats

S. O’Rahilly, G. Yeo, E. Ayuso, 2010, PloS one.

Trim28 Haploinsufficiency Triggers Bi-stable Epigenetic Obesity

M. Surani, S. O’Rahilly, T. Jenuwein, 2016, Cell.

Transcriptome analysis of embryonic and adult sensory axons reveals changes in mRNA repertoire localization.

Giovanni Coppola, Jeffery L Twiss, J. Fawcett, 2011, RNA.

Title : Six new loci associated with body mass index highlight a neuronal influence on body weight regulation

Eleanor, Willem, Ness, 2022 .

Where to go with FTO?

G. Yeo, Y. Tung, A. Coll, 2011, Trends in Endocrinology & Metabolism.

From GWAS to biology: lessons from FTO

G. Yeo, Y. Tung, Y. C. Tung, 2011, Annals of the New York Academy of Sciences.

Role for the obesity-related FTO gene in the cellular sensing of amino acids

F. Ashcroft, R. Cox, S. O’Rahilly, 2013, Proceedings of the National Academy of Sciences.

FTO is necessary for the induction of leptin resistance by high-fat feeding

S. O’Rahilly, V. Saudek, G. Yeo, 2015, Molecular metabolism.

Novel Leptin-Regulated Genes Revealed by Transcriptional Profiling of the Hypothalamic Paraventricular Nucleus

S. O’Rahilly, G. Yeo, Y. Tung, 2008, The Journal of Neuroscience.

Tachykinin-1 in the central nervous system regulates adiposity in rodents.

Henriette Kirchner, G. Yeo, Y. Tung, 2015, Endocrinology.

Protein-truncating variants in BSN are associated with severe adult-onset obesity, type 2 diabetes and fatty liver disease

R. Collins, D. Saleheen, J. Emberson, 2023, medRxiv.

Murine neuronatin deficiency is associated with a hypervariable food intake and bimodal obesity

S. O’Rahilly, V. Saudek, G. Yeo, 2021, Scientific Reports.

GDF15 and the beneficial actions of metformin in pre-diabetes

M. Chen, S. O’Rahilly, N. Sattar, 2019, bioRxiv.