D. Hollern

发表

A genomic analysis of mouse models of breast cancer reveals molecular features of mouse models and relationships to human breast cancer

E. Andrechek, D. Hollern, Daniel P Hollern, 2013, Breast Cancer Research.

Prediction and genetic demonstration of a role for activator E2Fs in Myc-induced tumors.

E. Andrechek, D. Hollern, I. Yuwanita, 2011, Cancer research.

Histological subtypes of mouse mammary tumors reveal conserved relationships to human cancers

E. Andrechek, D. Hollern, Matthew Swiatnicki, 2018, PLoS genetics.

E2F1 Drives Breast Cancer Metastasis by Regulating the Target Gene FGF13 and Altering Cell Migration

E. Andrechek, K. Gallo, D. Hollern, 2019, Scientific Reports.

NMDA receptor-mediated excitotoxicity depends on the coactivation of synaptic and extrasynaptic receptors

E. Andrechek, D. Hollern, X. Zhou, 2013, Cell Death and Disease.

Virus expression detection reveals RNA-sequencing contamination in TCGA

Lisle E. Mose, Sara R. Selitsky, David L. Marron, 2020, BMC Genomics.

B Cells and T Follicular Helper Cells Mediate Response to Checkpoint Inhibitors in High Mutation Burden Mouse Models of Breast Cancer

David L. Marron, C. Perou, Xiaping He, 2019, Cell.

Tip30 controls differentiation of murine mammary luminal progenitor to estrogen receptor-positive luminal cell through regulating FoxA1 expression

E. Andrechek, D. Hollern, Chengliang Zhang, 2014, Cell Death and Disease.

Integrated Molecular Characterization of Testicular Germ Cell Tumors

Joshua M. Stuart, Jeffrey A Jones, David I Heiman, 2018, Cell reports.

LPA receptor activity is basal specific and coincident with early pregnancy and involution during mammary gland postnatal development

Pilib Ó Broin, E. Andrechek, J. Greally, 2016, Scientific Reports.

Microneedle-mediated intratumoral delivery of anti-CTLA-4 promotes cDC1-dependent eradication of oral squamous cell carcinoma with limited irAEs

M. Gilardi, Daniella Kupor, Zhiyong Wang, 2021, bioRxiv.

Pyruvate kinase isoform expression alters nucleotide synthesis to impact cell proliferation.

William J. Israelsen, G. Stephanopoulos, M. Yaffe, 2014, Molecular cell.

B cells secrete GABA, which provokes a pro-tumor immune microenvironment.

M. Gilardi, D. Hollern, Daniel P. Hollern, 2021, Cancer cell.

Stimulation of Oncogene-Specific Tumor-Infiltrating T Cells through Combined Vaccine and αPD-1 Enable Sustained Antitumor Responses against Established HER2 Breast Cancer

C. Perou, L. Chodosh, Xiaping He, 2020, Clinical Cancer Research.

Chemotherapy coupled to macrophage inhibition induces T-cell and B-cell infiltration and durable regression in triple-negative breast cancer.

Jeffrey T. Chang, C. Perou, Zhandong Liu, 2022, Cancer research.

Tumour-infiltrating B cells: immunological mechanisms, clinical impact and therapeutic opportunities

B. Nelson, M. Gilardi, D. Hollern, 2022, Nature Reviews Cancer.

A genomic analysis of mouse models of breast cancer reveals molecular features of mouse models and relationships to human breast cancer

E. Andrechek, D. Hollern, Daniel P. Hollern, 2014, Breast Cancer Research.

FOXA1 overexpression suppresses interferon signaling and immune response in cancer.

Krishna R. Kalari, C. Perou, K. Kalari, 2021, The Journal of clinical investigation.

Insight into mammary gland development and tumor prevention in a newly developed metastatic mouse model of breast cancer

J. Nevins, E. Andrechek, Shams Reaz, 2021, bioRxiv.

E2F1 Drives Breast Cancer Metastasis by Regulating the Target Gene FGF13 and Altering Cell Migration

E. Andrechek, K. Gallo, D. Hollern, 2019, bioRxiv.

A mouse model featuring tissue-specific deletion of p53 and Brca1 gives rise to mammary tumors with genomic and transcriptomic similarities to human basal-like breast cancer

C. Perou, David B. Darr, J. Usary, 2018, Breast Cancer Research and Treatment.

Cdh1 and Pik3ca Mutations Cooperate to Induce Immune-Related Invasive Lobular Carcinoma of the Breast

C. Fan, C. Perou, Xiaping He, 2018, Cell reports.

A mouse model with T58A mutations in Myc reduces the dependence on KRas mutations and has similarities to claudin-low human breast cancer

E. Andrechek, D. Hollern, I. Yuwanita, 2013, Oncogene.

Chemotherapy coupled to macrophage inhibition leads to enhanced T and B cell infiltration and durable triple negative breast cancer regression

Jeffrey T. Chang, C. Perou, Zhandong Liu, 2021, bioRxiv.

PDGFRβ is an essential therapeutic target for BRCA1-deficient mammary tumors

C. Fan, C. Perou, Wei-Guo Zhu, 2021, Breast cancer research : BCR.

Loss of function of BRCA1 promotes EMT in mammary tumors through activation of TGFβR2 signaling pathway

Jason I. Herschkowitz, C. Fan, Wei-Guo Zhu, 2022, Cell Death & Disease.

The E2F Transcription Factors Regulate Tumor Development and Metastasis in a Mouse Model of Metastatic Breast Cancer

Robert D. Cardiff, R. Cardiff, E. Andrechek, 2014, Molecular and Cellular Biology.

Elevated phosphorylation of EGFR in NSCLC due to mutations in PTPRH

E. Andrechek, D. Hollern, Daniel P. Hollern, 2021, bioRxiv.

Tumor and Stem Cell Biology Prediction and Genetic Demonstration of a Role for Activator E 2 Fs in Myc-Induced Tumors

E. Andrechek, D. Hollern, I. Yuwanita, 2011 .

Identification of Jun loss promotes resistance to histone deacetylase inhibitor entinostat through Myc signaling in luminal breast cancer

C. Fan, C. Perou, David B. Darr, 2018, Genome Medicine.

FGFR4 regulates tumor subtype differentiation in luminal breast cancer and metastatic disease.

Sara R. Selitsky, David L. Marron, C. Fan, 2020, The Journal of clinical investigation.

Sensitivity to targeted therapy differs between HER2-amplified breast cancer cells harboring kinase and helical domain mutations in PIK3CA

Laura M. Heiser, K. Chin, J. Gray, 2021, Breast Cancer Research.

Microneedle-mediated intratumoral delivery of anti-CTLA-4 promotes cDC1-dependent eradication of oral squamous cell carcinoma with limited irAEs.

M. Gilardi, Daniella Kupor, Zhiyong Wang, 2022, Molecular cancer therapeutics.

NCOA5 deficiency promotes a unique liver protumorigenic microenvironment through p21WAF1/CIP1 overexpression, which is reversed by metformin

M. Kiupel, D. Hollern, Hua Xiao, 2020, Oncogene.

Virus expression detection reveals RNA-sequencing contamination in TCGA

Lisle E. Mose, David L. Marron, C. Perou, 2020, BMC Genomics.

A Review of FOXI3 Regulation of Development and Possible Roles in Cancer Progression and Metastasis

D. Hollern, C. Yates, A. Mukherjee, 2018, Front. Cell Dev. Biol..

Identification of Jun loss promotes resistance to histone deacetylase inhibitor entinostat through Myc signaling in luminal breast cancer

C. Fan, C. Perou, David B. Darr, 2018, Genome Medicine.

CAN-21-3714 2281..2297

Jeffrey T. Chang, C. Perou, Zhandong Liu, 2022 .