Hiroyuki Moritomo

发表

Discovery of ASP5878: Synthesis and structure-activity relationships of pyrimidine derivatives as pan-FGFRs inhibitors with improved metabolic stability and suppressed hERG channel inhibitory activity.

Ikumi Kuriwaki, M. Kameda, Kazuhiko Iikubo, 2022, Bioorganic & medicinal chemistry.

Identification of 4-benzylamino-2-[(4-morpholin-4-ylphenyl)amino]pyrimidine-5-carboxamide derivatives as potent and orally bioavailable STAT6 inhibitors.

Hiroyuki Moritomo, S. Kuromitsu, M. Orita, 2008, Bioorganic & medicinal chemistry.

Synthesis and biological evaluation of pyrido[3′,2′:4,5]furo[3,2- d ]pyrimidine derivatives as novel PI3 kinase p110α inhibitors

M. Waterfield, P. Workman, P. Parker, 2007 .

Synthesis and biological evaluation of 4-morpholino-2-phenylquinazolines and related derivatives as novel PI3 kinase p110alpha inhibitors.

M. Waterfield, P. Workman, P. Parker, 2006, Bioorganic & medicinal chemistry.

Synthesis and biological evaluation of pyrido[3',2':4,5]furo[3,2-d]pyrimidine derivatives as novel PI3 kinase p110alpha inhibitors.

M. Waterfield, P. Workman, P. Parker, 2007, Bioorganic & medicinal chemistry letters.

A new route to the isoindole nucleus via Furan–pyrrole ring-exchange

Hiroyuki Moritomo, K. Kanematsu, Mase Lee, 1994 .

Synthesis and biological evaluation of 4-morpholino-2-phenylquinazolines and related derivatives as novel PI3 kinase p110alpha inhibitors.

M. Waterfield, P. Workman, P. Parker, 2006, Bioorganic & medicinal chemistry.

Synthesis and structure-activity relationships of pyrimidine derivatives as potent and orally active FGFR3 inhibitors with both increased systemic exposure and enhanced in vitro potency.

Ikumi Kuriwaki, M. Kameda, Kazuhiko Iikubo, 2021, Bioorganic & medicinal chemistry.

Construction of three types of fused isoindoles via furan-pyrrole ring exchange reaction

Hiroyuki Moritomo, K. Kanematsu, M. Lee, 1996 .