Hiroshi Tomiyama

Discovery of ASP5878: Synthesis and structure-activity relationships of pyrimidine derivatives as pan-FGFRs inhibitors with improved metabolic stability and suppressed hERG channel inhibitory activity.

Ikumi Kuriwaki, M. Kameda, Kazuhiko Iikubo, 2022, Bioorganic & medicinal chemistry.

Renoprotective Effects of a Novel Receptor-Interacting Protein Kinase 2 Inhibitor, AS3334034, in Uninephrectomized Adriamycin-Induced Chronic Kidney Disease Rats

K. Tokita, Hiroshi Tomiyama, T. Ishikawa, 2020, The Journal of Pharmacology and Experimental Therapeutics.

SGLT2 selective inhibitor ipragliflozin reduces body fat mass by increasing fatty acid oxidation in high-fat diet-induced obese rats.

M. Sasamata, Y. Uchiyama, Hiroshi Tomiyama, 2014, European journal of pharmacology.

Synthesis of a C-glycoside analogue of sTn: an HIV- and tumor-associated antigen.

R. Linhardt, Hiroshi Tomiyama, B. Kuberan, 2003, Angewandte Chemie.

‘‘Ordered’’ structure in dilute solutions of biopolymers as studied by small‐angle x‐ray scattering

Hiroshi Tomiyama, T. Okubo, H. Matsuoka, 1985 .

Catalytic asymmetric intramolecular cyclopropanation of enol silyl ether. Synthesis of the phorbol CD-ring skeleton

M. Sodeoka, Hiroshi Tomiyama, M. Shibasaki, 1996 .

Methode de synthese d'un alcool optiquement actif

Hiroshi Tomiyama, M. Yokota, 2007 .

Discovery of Ipragliflozin (ASP1941): a novel C-glucoside with benzothiophene structure as a potent and selective sodium glucose co-transporter 2 (SGLT2) inhibitor for the treatment of type 2 diabetes mellitus.

Atsushi Noda, Hiroshi Tomiyama, M. Takeuchi, 2012, Bioorganic & medicinal chemistry.