J. Topham

发表

Identification and Analyses of Extra-Cranial and Cranial Rhabdoid Tumor Molecular Subgroups Reveal Tumors with Cytotoxic T Cell Infiltration

Steven J. M. Jones, Richard A. Moore, D. Gerhard, 2019, Cell reports.

NRG1 Gene Fusions Are Recurrent, Clinically Actionable Gene Rearrangements in KRAS Wild-Type Pancreatic Ductal Adenocarcinoma

Steven J. M. Jones, Richard A. Moore, E. Pleasance, 2019, Clinical Cancer Research.

Integration of Whole-Genome Sequencing With Circulating Tumor DNA Analysis Captures Clonal Evolution and Tumor Heterogeneity in Non-V600 BRAF Mutant Colorectal Cancer.

Steven J. M. Jones, Ryan D. Morin, M. Marra, 2020, Clinical colorectal cancer.

Airway Gene Expression Correlates of Respiratory Syncytial Virus Disease Severity and Microbiome Composition in Infants

J. Holden-Wiltse, J. Topham, A. Grier, 2021 .

The CCTG PA.7 phase II trial of gemcitabine and nab-paclitaxel with or without durvalumab and tremelimumab as initial therapy in metastatic pancreatic ductal adenocarcinoma

D. Tu, S. Gill, S. Welch, 2022, Nature Communications.

Integrative analysis of KRAS wildtype metastatic pancreatic ductal adenocarcinoma reveals mutation and expression-based similarities to cholangiocarcinoma

Steven J. M. Jones, Richard A. Moore, M. Marra, 2022, Nature Communications.

Regulation of pH by Carbonic Anhydrase 9 Mediates Survival of Pancreatic Cancer Cells With Activated KRAS in Response to Hypoxia.

S. C. Chafe, A. Bashashati, S. Shah, 2019, Gastroenterology.

Endogenous Retrovirus Transcript Levels Are Associated with Immunogenic Signatures in Multiple Metastatic Cancer Types

Steven J. M. Jones, Richard A. Moore, E. Pleasance, 2020, Molecular Cancer Therapeutics.

Transcription phenotypes of pancreatic cancer are driven by genomic events during tumor evolution

Steven J. M. Jones, Lincoln D. Stein, P. Campbell, 2020, Nature Genetics.

Uncovering Clinically Relevant Gene Fusions with Integrated Genomic and Transcriptomic Profiling of Metastatic Cancers

Steven J. M. Jones, Richard A. Moore, E. Pleasance, 2020, Clinical Cancer Research.

Clinical and genomic characterisation of mismatch repair deficient pancreatic adenocarcinoma

F. Notta, S. Gallinger, R. Denroche, 2020, Gut.

Transcription phenotypes of pancreatic cancer are driven by genomic events during tumor evolution

P. Campbell, B. Haibe-Kains, M. Marra, 2020, Nature Genetics.

Genome and Transcriptome Biomarkers of Response to Immune Checkpoint Inhibitors in Advanced Solid Tumors

Steven J. M. Jones, Richard A. Moore, Scott D. Brown, 2020, Clinical Cancer Research.

Altered Gene Expression along the Glycolysis–Cholesterol Synthesis Axis Is Associated with Outcome in Pancreatic Cancer

Steven J. M. Jones, Richard A. Moore, M. Marra, 2019, Clinical Cancer Research.

The neoantigen landscape of the coding and noncoding cancer genome space.

E. Pleasance, A. Karsan, E. Titmuss, 2022, The Journal of molecular diagnostics : JMD.

Delving into Early-onset Pancreatic Ductal Adenocarcinoma: How Does Age Fit In?

Steven J. M. Jones, Richard A. Moore, M. Marra, 2020, Clinical Cancer Research.

MicroRNA Expression-Based Model Indicates Event-Free Survival in Pediatric Acute Myeloid Leukemia

D. Gerhard, E. Pleasance, M. Marra, 2017, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Circulating tumor DNA: toward evolving the clinical paradigm of pancreatic ductal adenocarcinoma

J. Topham, D. Renouf, D. Schaeffer, 2023, Therapeutic advances in medical oncology.

Circulating Tumor DNA Identifies Diverse Landscape of Acquired Resistance to Anti–Epidermal Growth Factor Receptor Therapy in Metastatic Colorectal Cancer

H. Feilotter, D. Tu, H. Kennecke, 2022, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Author Correction: Transcription phenotypes of pancreatic cancer are driven by genomic events during tumor evolution

Steven J. M. Jones, Lincoln D. Stein, P. Campbell, 2020, Nature Genetics.

Impact of consensus molecular subtyping (CMS) on survival in the CO.26 trial of durvalumab plus tremelimumab versus best supportive care (BSC) in metastatic colorectal cancer (mCRC).

H. Feilotter, D. Tu, S. Kopetz, 2022, Journal of Clinical Oncology.

Homologous recombination deficiency signatures in gastrointestinal and thoracic cancers correlate with platinum therapy duration

E. Pleasance, M. Marra, K. Mungall, 2023, npj Precision Oncology.

Tumor infiltrating neutrophils and gland formation predict overall survival and molecular subgroups in pancreatic ductal adenocarcinoma

Steven J. M. Jones, Richard A. Moore, M. Marra, 2020, Cancer medicine.

Subtype-Discordant Pancreatic Ductal Adenocarcinoma Tumors Show Intermediate Clinical and Molecular Characteristics

Steven J. M. Jones, Richard A. Moore, M. Marra, 2020, Clinical Cancer Research.

Stroma vs epithelium‐enhanced prognostics through histologic stratification in pancreatic ductal adenocarcinoma

S. Kalloger, C. Chow, H. Wong, 2020, International journal of cancer.

Clinicopathological features of pancreatic cancer-related diabetes.

S. Kalloger, H. Wong, J. Topham, 2020 .

Predictive value of plasma tumor mutation burden (TMB) in the CCTG PA.7 trial: Gemcitabine (GEM) and nab-paclitaxel (Nab-P) vs. GEM, nab-P, durvalumab (D) and tremelimumab (T) as first line therapy in metastatic pancreatic ductal adenocarcinoma (mPDAC).

D. Tu, S. Gill, S. Welch, 2021 .

Optimizing the number of variants tracked to follow disease burden with circulating tumor DNA assays in metastatic colorectal cancer

H. Feilotter, D. Tu, H. Kennecke, 2023, Therapeutic advances in medical oncology.

Sequencing Strategies to Guide Decision Making in Cancer Treatment

M. Marra, J. Topham, 2016, PLoS medicine.

Immune Activation following Irbesartan Treatment in a Colorectal Cancer Patient: A Case Study

M. Marra, S. Kalloger, A. Mungall, 2023, International journal of molecular sciences.

Tissue and plasma tumor mutation burden (TMB) as predictive biomarkers in the CO.26 trial of durvalumab + tremelimumab (D+T) versus best supportive care (BSC) in metastatic colorectal cancer (mCRC).

H. Feilotter, D. Tu, H. Kennecke, 2021 .

Nutrient scavenging-fueled growth in pancreatic cancer depends on caveolae-mediated endocytosis under nutrient-deprived conditions

J. Topham, J. Karasinska, D. Renouf, 2024, Science advances.

Clonal hematopoiesis of indeterminate potential (CHIP), treatment outcomes and adverse events in gastrointestinal cancers: A pooled analysis of clinical trial and real-world data.

D. Jonker, E. Titmuss, J. Topham, 2024, Journal of Clinical Oncology.