R. Weaver

发表

Virtual chromatographic resolution enhancement in cryoflow LC-NMR experiments via statistical total correlation spectroscopy.

Manfred Spraul, Jeremy K Nicholson, Alison Campbell, 2007, Analytical chemistry.

The olivacine derivative s 16020 (9-hydroxy-5,6-dimethyl-N-[2-(dimethylamino)ethyl)-6H-pyrido(4,3-B)-carbazole-1-carboxamide) induces CYP1A and its own metabolism in human hepatocytes in primary culture.

G. Scarfe, R. Weaver, P. Maurel, 2004, Drug metabolism and disposition: the biological fate of chemicals.

Identification and quantification of glutathione adducts of clozapine using ultra-high-performance liquid chromatography with orthogonal acceleration time-of-flight mass spectrometry and inductively coupled plasma mass spectrometry.

I. Wilson, R. Weaver, Christopher J. Smith, 2011, Rapid communications in mass spectrometry : RCM.

Identification and reduction of ion suppression effects on pharmacokinetic parameters by polyethylene glycol 400.

R. Weaver, R. Riley, 2006, Rapid communications in mass spectrometry : RCM.

Cytochrome P450 inhibition using recombinant proteins and mass spectrometry/multiple reaction monitoring technology in a cassette incubation.

R. Weaver, R. Riley, I. Beattie, 2003, Drug metabolism and disposition: the biological fate of chemicals.

Isolation, structural identification, synthesis, and pharmacological profiling of 1,2-trans-dihydro-1,2-diol metabolites of the utrophin modulator ezutromid.

G. Wynne, K. Davies, M. Chatzopoulou, 2019, Journal of medicinal chemistry.

Discovery of potent CRTh2 (DP2) receptor antagonists.

S. Teague, R. Weaver, S. Paine, 2006, Bioorganic & medicinal chemistry letters.

Hit-to-Lead studies: the discovery of potent adamantane amide P2X7 receptor antagonists.

Martin Braddock, Keith Bowers, Richard Weaver, 2003, Bioorganic & medicinal chemistry letters.

Discovery of pyrazoles as novel FPR1 antagonists.

M. Wenlock, J. Unitt, Bryan E. Roberts, 2011, Bioorganic & medicinal chemistry letters.

Time-dependent CYP inhibition

Robert J Riley, Ken Grime, Richard Weaver, 2007, Expert opinion on drug metabolism & toxicology.

Design, Synthesis, and Evaluation of Lung-Retentive Prodrugs for Extending the Lung Tissue Retention of Inhaled Drugs

R. Weaver, C. Bosquillon, Michael J. Stocks, 2022, Journal of medicinal chemistry.

Rapid high-performance liquid chromatographic method for the separation of hydroxylated testosterone metabolites.

R. Weaver, K. Grime, P. Whalley, 2001, Journal of Chromatography B: Biomedical Sciences and Applications.

Discovery of potent and selective adamantane-based small-molecule P2X(7) receptor antagonists/interleukin-1beta inhibitors.

Martin Braddock, Mark Furber, Keith Bowers, 2007, Journal of medicinal chemistry.