C. Harding

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Proteomics and Network Analyses Reveal Inhibition of Akt‐mTOR Signaling in CD4+ T Cells by Mycobacterium tuberculosis Mannose‐Capped Lipoarabinomannan

M. Chance, R. Ewing, Sean Maxwell, 2017, Proteomics.

Mycobacterium tuberculosis LprA Is a Lipoprotein Agonist of TLR2 That Regulates Innate Immunity and APC Function1

C. Harding, W. Boom, A. Gehring, 2006, The Journal of Immunology.

Pathways of antigen processing.

C. Harding, C V Harding, 1991, Current opinion in immunology.

The efficiency of antigen delivery from macrophage phagosomes into cytoplasm for MHC class I-restricted antigen presentation.

J. Swanson, C. Harding, Y. Oh, 1997, Vaccine.

Quantitation of antigen-presenting cell MHC class II/peptide complexes necessary for T-cell stimulation

Emil R. Unanue, Clifford V. Harding, E. Unanue, 1990, Nature.

Efficient metabolic engineering of GM3 on tumor cells by N-phenylacetyl-D-mannosamine.

C. Harding, P. Chefalo, Zhongwu Guo, 2006, Biochemistry.

Preparation and immunological studies of protein conjugates of N-acylneuraminic acids

C. Harding, P. Chefalo, Zhongwu Guo, 2003, Glycoconjugate Journal.

Elemental and ultrastructural analysis of specific human lens opacities.

L. Chylack, C. Harding, W. Bobrowski, 1982, Investigative ophthalmology & visual science.

Interaction of bacteria with antigen presenting cells: influences on antigen presentation and antibacterial immunity.

C. Harding, M. Wick, L. Ramachandra, 2003, Current opinion in immunology.

Antigenic Epitopes Expressed in Salmonella typhimunium

J. Pfeifer, C. Harding, M. Wick, 2022 .

Plasmacytoid Dendritic Cells Mediate Synergistic Effects of HIV and Lipopolysaccharide on CD27+ IgD– Memory B Cell Apoptosis

M. Lederman, N. Greenspan, Yong Gao, 2014, Journal of Virology.

A critical role for alpha-synuclein in development and function of T lymphocytes.

C. Harding, H. Meyerson, W. Xiao, 2016, Immunobiology.

Phagocytic processing of bacterial antigens for class I MHC presentation to T cells

J. Pfeifer, S. Normark, C. Harding, 1993, Nature.

Phagosomes are fully competent antigen-processing organelles that mediate the formation of peptide:class II MHC complexes.

C. Harding, L. Ramachandra, R. Song, 1999, Journal of immunology.

Mycobacterium tuberculosis inhibits MHC class II antigen processing in murine bone marrow macrophages.

C. Harding, W. Boom, E. Noss, 1998, Cellular immunology.

Disordered Toll‐like receptor 2 responses in the pathogenesis of pulmonary sarcoidosis

J. Tomashefski, C. Harding, J. Kern, 2013, Clinical and experimental immunology.

Mycobacterium tuberculosis LprG (Rv1411c): A Novel TLR-2 Ligand That Inhibits Human Macrophage Class II MHC Antigen Processing1

John T. Belisle, Adam J. Gehring, Clifford V. Harding, 2004, The Journal of Immunology.

Mycobacterium tuberculosis Lipoprotein and Lipoglycan Binding to Toll-Like Receptor 2 Correlates with Agonist Activity and Functional Outcomes

C. Harding, W. Boom, Edward T. Richardson, 2018, Infection and Immunity.

Anergy via GRAIL T + Induces CD 4 Mycobacterium tuberculosis Mannose-Capped Lipoarabinomannan from

A. F. Karim, O. J. Sande, Xuedong Ding, 2015 .

Mycobacterium tuberculosis ManLAM inhibits T-cell-receptor signaling by interference with ZAP-70, Lck and LAT phosphorylation.

A. Levine, O. J. Sande, C. Harding, 2012, Cellular immunology.

TLR2 Signaling Depletes IRAK1 and Inhibits Induction of Type I IFN by TLR7/9

Derek W. Abbott, C. Harding, W. Boom, 2012, The Journal of Immunology.

Rv2468c, a novel Mycobacterium tuberculosis protein that costimulates human CD4+ T cells through VLA‐5

Xuedong Ding, C. Harding, R. Rojas, 2012, Journal of leukocyte biology.

Mycobacterium tuberculosis Lipoproteins Directly Regulate Human Memory CD4+ T Cell Activation via Toll-Like Receptors 1 and 2

Xuedong Ding, C. Harding, R. Rojas, 2010, Infection and Immunity.

TLR2 and its co-receptors determine responses of macrophages and dendritic cells to lipoproteins of Mycobacterium tuberculosis.

D. Golenbock, C. Harding, W. Boom, 2009, Cellular immunology.

Mycobacterium tuberculosis Cell Wall Glycolipids Directly Inhibit CD4+ T-Cell Activation by Interfering with Proximal T-Cell-Receptor Signaling

C. Harding, R. Rojas, W. Boom, 2009, Infection and Immunity.

Mycobacterium tuberculosis lipoprotein‐induced association of TLR2 with protein kinase C ζ in lipid rafts contributes to reactive oxygen species‐dependent inflammatory signalling in macrophages

Ji-yeon Lee, C. Harding, Sung Joong Lee, 2008, Cellular microbiology.

Mycobacterium tuberculosis 19-kDa Lipoprotein Inhibits IFN-γ-Induced Chromatin Remodeling of MHC2TA by TLR2 and MAPK Signaling1

C. Harding, W. Boom, D. C. Schultz, 2006, The Journal of Immunology.

Class II MHC antigen presentation defect in neonatal monocytes is not correlated with decreased MHC-II expression.

C. Harding, J. Smialek, D. Tisch, 2006, Cellular immunology.

The Mycobacterial 38-Kilodalton Glycolipoprotein Antigen Activates the Mitogen-Activated Protein Kinase Pathway and Release of Proinflammatory Cytokines through Toll-Like Receptors 2 and 4 in Human Monocytes

J. Son, Saet-Byel Jung, C. Harding, 2006, Infection and Immunity.

Induces Adhesion to Fibronectin T Cells and + Integrin ( VLA-5 ) on CD 4 1 β 5 α Binds Mycobacterium tuberculosis Phosphatidylinositol Mannoside from Henry Boom

J. Belisle, C. Harding, R. Rojas, 2006 .

TLR 2 and MAPK Signaling by MHC 2 TA Chromatin Remodeling of-Induced γ Lipoprotein Inhibits IFN-19-kDa Mycobacterium tuberculosis Boom and

C. Harding, W. Boom, D. C. Schultz, 2006 .

Phosphatidylinositol Mannoside from Mycobacterium tuberculosis Binds α5β1 Integrin (VLA-5) on CD4+ T Cells and Induces Adhesion to Fibronectin1

J. Belisle, C. Harding, R. Rojas, 2006, The Journal of Immunology.

Phagosomal Processing of Mycobacterium tuberculosis Antigen 85B Is Modulated Independently of Mycobacterial Viability and Phagosome Maturation

C. Harding, W. Boom, J. Smialek, 2005, Infection and Immunity.

Induction of Type I IFN by TLR7/9 TLR2 Signaling Depletes IRAK1 and Inhibits

C. Harding, W. Boom, D. Simmons, 2022 .

T-cell hybridomas from HLA-transgenic mice as tools for analysis of human antigen processing.

C. Harding, W. Boom, J. Schreiber, 2003, Journal of immunological methods.

CCAAT/Enhancer-Binding Protein β and δ Binding to CIITA Promoters Is Associated with the Inhibition of CIITA Expression in Response to Mycobacterium tuberculosis 19-kDa Lipoprotein1

Jianqi Yang, C. Harding, W. Boom, 2007, The Journal of Immunology.

Histochemical Localization of Acid Phosphatase in the Injured Rabbit Lens

C. Harding, L. Binder, J. Reddan, 1975 .

Liposome-encapsulated antigens are processed in lysosomes, recycled, and presented to T cells

E. Unanue, J. Slot, H. Geuze, 1991, Cell.

Antigen processing and CD24 expression determine antigen presentation by splenic CD4+ and CD8+ dendritic cells

C. Harding, D. Askew, 2008, Immunology.

Activation of human CD8+ alpha beta TCR+ cells by Mycobacterium tuberculosis via an alternate class I MHC antigen-processing pathway.

C. Harding, W. Boom, D. Canaday, 1999, Journal of immunology.

Liposome-encapsulated antigens engender lysosomal processing for class II MHC presentation and cytosolic processing for class I presentation.

E. Unanue, C. Harding, O. Kanagawa, 1991, Journal of immunology.

Neutrophils Process Exogenous Bacteria Via an Alternate Class I MHC Processing Pathway for Presentation of Peptides to T Lymphocytes1

C. Harding, N. Potter, 2001, The Journal of Immunology.

Phagocytic antigen processing and effects of microbial products on antigen processing and T‐cell responses

C. Harding, W. Boom, A. Krieg, 1999, Immunological reviews.

MHC molecules and microbial antigen processing in phagosomes.

C. Harding, L. Ramachandra, D. Simmons, 2009, Current opinion in immunology.

CpG DNA Induces Maturation of Dendritic Cells with Distinct Effects on Nascent and Recycling MHC-II Antigen-Processing Mechanisms

C. Harding, A. Krieg, R. Chu, 2000, The Journal of Immunology.

Phagocytic processing of exogenous particulate antigens by macrophages for presentation by class I MHC molecules.

C. Harding, R. Song, Clifford V. Harding, 1994, Journal of immunology.

Cross-Processing and -Presentation by B Fusion Protein Enhances Class I MHC Mycobacterium tuberculosis Heat Shock

C. Harding, A. Tobian, H. David, 2013 .

Mycobacterium tuberculosis Heat Shock Fusion Protein Enhances Class I MHC Cross-Processing and -Presentation by B Lymphocytes1

C. Harding, A. Tobian, D. Canaday, 2005, The Journal of Immunology.

Bacterial Heat Shock Proteins Promote CD91-Dependent Class I MHC Cross-Presentation of Chaperoned Peptide to CD8+ T Cells by Cytosolic Mechanisms in Dendritic Cells versus Vacuolar Mechanisms in Macrophages1

C. Harding, W. Boom, A. Tobian, 2004, The Journal of Immunology.

Bacterial Heat Shock Proteins Enhance Class II MHC Antigen Processing and Presentation of Chaperoned Peptides to CD4+ T Cells1

C. Harding, A. Tobian, D. Canaday, 2004, The Journal of Immunology.

Circulating CD4+ and CD8+ T cells are activated in inflammatory bowel disease and are associated with plasma markers of inflammation

M. Lederman, A. Levine, P. Fu, 2013, Immunology.

Regulation of antigen presentation by Mycobacterium tuberculosis: a role for Toll-like receptors

C. Harding, W. Boom, 2010, Nature Reviews Microbiology.

Immunogenic peptides bind to class II MHC molecules in an early lysosomal compartment.

H. Geuze, C. Harding, 1993, Journal of immunology.

Turnover of Ia-peptide complexes is facilitated in viable antigen-presenting cells: biosynthetic turnover of Ia vs. peptide exchange.

E. Unanue, C. Harding, R. W. Roof, 1989, Proceedings of the National Academy of Sciences of the United States of America.

Reduction of disulfide bonds within lysosomes is a key step in antigen processing.

E. Unanue, C. Harding, D. Collins, 1991, Journal of immunology.

Early endosomes and a late endocytic compartment generate different peptide-class II MHC complexes via distinct processing mechanisms.

C. Harding, R. Chu, J. Griffin, 1997, Journal of immunology.

Lipoprotein Promotes Neutrophil Activation 19-kDa Mycobacterium tuberculosis

C. Harding, W. Boom, C. Neufert, 2001 .

Presenting Exogenous Antigen to T Cells

C. Harding, L. Ramachandra, 1997, Current protocols in immunology.

Presenting Exogenous Antigen to T Cells

C. Harding, 1997, Current protocols in immunology.

Down-regulation of the transporter for antigen presentation, proteasome subunits, and class I major histocompatibility complex in tumor cell lines.

M. Sy, C. Harding, J. France, 1998, Cancer research.

Synthesis and immunological properties of N-modified GM3 antigens as therapeutic cancer vaccines.

C. Harding, P. Chefalo, Zhongwu Guo, 2005, Journal of medicinal chemistry.

Tapasin−/− and TAP1−/− Macrophages Are Deficient in Vacuolar Alternate Class I MHC (MHC-I) Processing due to Decreased MHC-I Stability at Phagolysosomal pH1

A. G. Grandea, C. Harding, P. Chefalo, 2003, The Journal of Immunology.

Macrophages Are Deficient in Vacuolar Alternate Class I MHC (MHC-I) Processing due to Decreased MHC-I Stability at Phagolysosomal pH

L. Kaer, A. G. Grandea, C. Harding, 2003 .

Processing of Exogenous Antigens for Presentation by Class I MHC Molecules Involves Post-Golgi Peptide Exchange Influenced by Peptide-MHC Complex Stability and Acidic pH1

C. Harding, P. Chefalo, 2001, The Journal of Immunology.

Toll-Like Receptor 2-Dependent Inhibition of Macrophage Class II MHC Expression and Antigen Processing by 19-kDa Lipoprotein of Mycobacterium tuberculosis

D. Golenbock, J. Belisle, C. Harding, 2001 .

CCR5 promoter polymorphism determines macrophage CCR5 density and magnitude of HIV-1 propagation in vitro.

M. Lederman, H. Valdez, S. Bruse, 2003, Clinical immunology.

Cellular and molecular aspects of antigen processing and the function of class II MHC molecules.

C. Harding, 1993, American journal of respiratory cell and molecular biology.

Antigen processing and intracellular Ia. Possible roles of endocytosis and protein synthesis in Ia function.

E. Unanue, C. Harding, 1989, Journal of immunology.

Mycobacterial lipoprotein activates autophagy via TLR2/1/CD14 and a functional vitamin D receptor signalling

J. Son, C. Harding, D. Shin, 2010, Cellular Microbiology.

Effects of pH and polysaccharides on peptide binding to class II major histocompatibility complex molecules.

E. Unanue, P. Allen, C. Harding, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Initial assessment of α-synuclein structure in platelets

C. Harding, H. Meyerson, R. Maitta, 2021, Journal of Thrombosis and Thrombolysis.

α‐Synuclein concentration increases over time in plasma supernatant of single donor platelets

C. Harding, H. Hong, R. Maitta, 2018, European journal of haematology.

Ultrastructural changes in peripheral blood leukocytes in α-synuclein knockout mice.

C. Harding, R. Maitta, A. Shameli, 2018, Blood cells, molecules & diseases.

A comparative study of corneal epithelial cell surfaces utilizing the scanning electron microscope.

C. Harding, M. Bagchi, V. Peters, 1974, Investigative ophthalmology.

Calcium-containing opacities in the human lens.

L. Chylack, C. Harding, W. Bobrowski, 1983, Investigative ophthalmology & visual science.

The Permeability Characteristics of the Nuclear Envelope at Interphase

C. Harding, C. Feldherr, 1964 .

MyD88-dependent interplay between myeloid and endothelial cells in the initiation and progression of obesity-associated inflammatory diseases

S. Hazen, R. Ransohoff, Jonathan D. Smith, 2014, The Journal of experimental medicine.

Glycopeptides bind MHC molecules and elicit specific T cell responses.

E. Unanue, J. Kihlberg, C. Harding, 1993, Journal of immunology.

Choosing and Preparing Antigen‐Presenting Cells

C. Harding, 1997, Current protocols in immunology.

Faculty Opinions recommendation of Mice completely lacking immunoproteasomes show major changes in antigen presentation.

C. Harding, 2012 .

Choosing and Preparing Antigen‐Presenting Cells

C. Harding, D. Canaday, L. Ramachandra, 1997, Current protocols in immunology.

Human Naive B Cells Cells by CpG Oligodeoxynucleotide-Primed T + Presentation of Soluble Antigens to CD8

M. Lederman, C. Harding, S. Sieg, 2011 .

Presentation of Soluble Antigens to CD8+ T Cells by CpG Oligodeoxynucleotide-Primed Human Naive B Cells

M. Lederman, C. Harding, S. Sieg, 2011, The Journal of Immunology.

Phosphoantigen Presentation by Macrophages to Mycobacterium tuberculosis-Reactive Vγ9Vδ2+ T Cells: Modulation by Chloroquine

C. Harding, R. Rojas, W. Boom, 2002, Infection and Immunity.

Arrhythmias in Cardiac Sarcoidosis Bench to Bedside

Ben A. Lin, Jagmeet P. Singh, M. Chung, 2021, Circulation. Arrhythmia and electrophysiology.

Phagocytic processing of antigens for presentation by class II major histocompatibility complex molecules

C. Harding, L. Ramachandra, E. Noss, 1999, Cellular microbiology.

Complexes the Formation of Peptide:Class II MHC Antigen-Processing Organelles That Mediate Phagosomes Are Fully Competent

C. Harding, L. Ramachandra, R. Song, 1999 .

Phosphoantigen presentation by macrophages to mycobacterium tuberculosis--reactive Vgamma9Vdelta2+ T cells: modulation by chloroquine.

C. Harding, R. Rojas, W. Boom, 2002, Infection and immunity.

Type I IFN Drives a Distinctive Dendritic Cell Maturation Phenotype That Allows Continued Class II MHC Synthesis and Antigen Processing

C. Harding, W. Boom, H. Meyerson, 2012, The Journal of Immunology.

Antigen Processing Continued Class II MHC Synthesis and Cell Maturation Phenotype That Allows Type I IFN Drives a Distinctive Dendritic

C. Harding, W. Boom, H. Meyerson, 2012 .

Class II MHC molecules are present in macrophage lysosomes and phagolysosomes that function in the phagocytic processing of Listeria monocytogenes for presentation to T cells

H. Geuze, C. Harding, 1992, The Journal of cell biology.

Inhibition of Class II Major Histocompatibility Complex Antigen Processing by Escherichia coli Heat-Labile Enterotoxin Requires an Enzymatically Active A Subunit

C. Harding, W. Cieplak, J. Nedrud, 1998, Infection and Immunity.

Molecular Detection of SARS-CoV-2 Infection in FFPE Samples and Histopathologic Findings in Fatal SARS-CoV-2 Cases

Hannah Gilmore, C. Harding, M. Sekulic, 2020, American journal of clinical pathology.

CD4+ and CD8+ T Cells Kill Intracellular Mycobacterium tuberculosis by a Perforin and Fas/Fas Ligand-Independent Mechanism1

R. Wilkinson, C. Harding, W. Boom, 2001, The Journal of Immunology.

CD4 and CD8 T Cells Kill Intracellular Mycobacterium tuberculosis by a Perforin and Fas/Fas Ligand-Independent Mechanism

R. Wilkinson, C. Harding, W. Boom, 2001 .

Fas / Fas Ligand-Independent Mechanism by a Perforin and Mycobacterium tuberculosis T Cells Kill Intracellular + and CD 8 + CD 4

R. Wilkinson, C. Harding, W. Boom, 2001 .

Toll-Like Receptor 2-Dependent Extracellular Signal-Regulated Kinase Signaling in Mycobacterium tuberculosis-Infected Macrophages Drives Anti-Inflammatory Responses and Inhibits Th1 Polarization of Responding T Cells

P. Tsichlis, C. Harding, W. Boom, 2015, Infection and Immunity.

Cellular mechanisms ofantigen processing andthefunction ofclass Iand11major histocompatibili ty complex molecules

C. Harding, 1990 .

Further Analysis of the Role of MHC Molecules in Antigen Presentation

E. Unanue, C. Harding, I. Luescher, 1989 .

Mechanisms of Antigen Processing

E. Unanue, C. Harding, F. Leyva-Cobián, 1988, Immunological reviews.

Antigen Processing of the Heptavalent Pneumococcal Conjugate Vaccine Carrier Protein CRM197 Differs Depending on the Serotype of the Attached Polysaccharide

C. Harding, J. Schreiber, D. Canaday, 2003, Infection and Immunity.

Surfactant protein D enhances bacterial antigen presentation by bone marrow-derived dendritic cells.

C. Harding, E. Mostaghel, J. Wright, 2001, American journal of physiology. Lung cellular and molecular physiology.

CpG DNA switches on Th1 immunity and modulates antigen-presenting cell function.

C. Harding, D. Askew, R. Chu, 2000, Current topics in microbiology and immunology.

Mycobacterium tuberculosis Promotes HIV trans-Infection and Suppresses Major Histocompatibility Complex Class II Antigen Processing by Dendritic Cells

C. Harding, N. Pecora, D. Canaday, 2010, Journal of Virology.

Low‐temperature inhibition of antigen processing and iron uptake from transferrin: Deficits in endosome functions at 18 °C

E. Unanue, C. Harding, Clifford V. Harding, 1990 .

Inhibition of Major Histocompatibility Complex II Expression and Antigen Processing in Murine Alveolar Macrophages by Mycobacterium bovis BCG and the 19-Kilodalton Mycobacterial Lipoprotein

C. Harding, W. Boom, M. Torres, 2004, Infection and Immunity.

Distinct effects of recombinant cholera toxin B subunit and holotoxin on different stages of class II MHC antigen processing and presentation by macrophages.

C. Harding, J. Nedrud, M. Matousek, 1996, Journal of immunology.

History and Outcomes of 50 Years of Physician-Scientist Training in Medical Scientist Training Programs.

M. Akabas, C. Harding, Olaf S Andersen, 2017, Academic medicine : journal of the Association of American Medical Colleges.

Phagosomes Acquire Nascent and Recycling Class II MHC Molecules but Primarily Use Nascent Molecules in Phagocytic Antigen Processing1

C. Harding, L. Ramachandra, 2000, The Journal of Immunology.

ProcessingNascent Molecules in Phagocytic Antigen Class II MHC Molecules but Primarily Use Phagosomes Acquire Nascent and Recycling

C. Harding, L. Ramachandra, 2000 .

Toll-Like Receptor 2-Dependent Inhibition of Macrophage Class II MHC Expression and Antigen Processing by 19-kDa Lipoprotein of Mycobacterium tuberculosis1

D. Golenbock, J. Radolf, J. Belisle, 2001, The Journal of Immunology.

Mycobacterium tuberculosis Antigen Processing by 19-kDa Lipoprotein of Macrophage Class II MHC Expression and Toll-Like Receptor 2-Dependent Inhibition of Boom and

D. Golenbock, J. Radolf, J. Belisle, 2001 .

Class I MHC presentation of exogenous antigens

C. Harding, 1996, Journal of Clinical Immunology.

of Type I IFN in Dendritic Cells TLR-Dependent and -Independent Induction CpG-B Oligodeoxynucleotides Inhibit

Derek W. Abbott, C. Harding, Yi C. Liu, 2010 .

Alternate Class I MHC Antigen Processing Is Inhibited by Toll-Like Receptor Signaling Pathogen-Associated Molecular Patterns: Mycobacterium tuberculosis 19-kDa Lipoprotein, CpG DNA, and Lipopolysaccharide1

C. Harding, W. Boom, A. Tobian, 2003, The Journal of Immunology.

Lipopolysaccharide 19-kDa Lipoprotein , Mycobacterium tuberculosis Pathogen-Associated Molecular Patterns : Inhibited by Toll-Like Receptor Signaling Alternate Class I MHC Antigen Processing Is

C. Harding, W. Boom, L. Ramachandra, 2003 .

Role of Phagosomes and Major Histocompatibility Complex Class II (MHC-II) Compartment in MHC-II Antigen Processing of Mycobacterium tuberculosis in Human Macrophages

C. Harding, R. Rojas, W. Boom, 2006, Infection and Immunity.

The impact of glycosylation on HLA-DR1-restricted T cell recognition of type II collagen in a mouse model.

J. Isaacs, R. Holmdahl, D. Altmann, 2006, Arthritis and rheumatism.

Differences in antigen processing with haplotype‐mismatched MHC class II heterodimers: AαdAβb heterodimers participate in early endosomal processing

C. Harding, D. Askew, 2002 .

Processing of Mycobacterium tuberculosis Antigen 85B Involves Intraphagosomal Formation of Peptide–Major Histocompatibility Complex II Complexes and Is Inhibited by Live Bacilli that Decrease Phagosome Maturation

C. Harding, W. Boom, L. Ramachandra, 2001, The Journal of experimental medicine.

Phagocytic processing of antigens for presentation by MHC molecules.

C. Harding, 1995, Trends in cell biology.

Processing of liposome-encapsulated antigens targeted to specific subcellular compartments.

E. Unanue, C. Harding, D. Collins, 1992, Research in immunology.

A propagated stimulation of DNA synthesis and cell division.

B. D. Srinivasan, C. Harding, 1961, Experimental cell research.

Cellular mechanisms of antigen processing and the function of class I and II major histocompatibility complex molecules.

E. Unanue, C. Harding, 1990, Cell regulation.

Bacterial Membrane Vesicles Mediate the Release of Mycobacterium tuberculosis Lipoglycans and Lipoproteins from Infected Macrophages

C. Harding, W. Boom, P. Wearsch, 2015, The Journal of Immunology.

MacrophagesLipoglycans and Lipoproteins from Infected Mycobacterium tuberculosis Release of Bacterial Membrane Vesicles Mediate the

C. Harding, W. Boom, P. Wearsch, 2015 .

B- and T-Cell Immune Responses to Pneumococcal Conjugate Vaccines: Divergence between Carrier- and Polysaccharide-Specific Immunogenicity

N. Greenspan, C. Harding, J. Schreiber, 1999, Infection and Immunity.

Use of a whole‐cell ELISA to detect additional antibodies in setting of suspected heparin‐induced thrombocytopenia

C. Harding, R. Maitta, Eva Bashover, 2019, European journal of haematology.

Toll-Like Receptor 2-Tpl2-Dependent ERK Signaling Drives Inverse Interleukin 12 Regulation in Dendritic Cells and Macrophages

C. Harding, W. Boom, Sarah G. Groft, 2020, Infection and Immunity.

The NQR pathway regulates the immunomodulatory function of Bacteroides thetaiotaomicron

C. Harding, Philip P. Ahern, E. Martens, 2022, bioRxiv.

Processing of Exogenous Antigens for Presentation by Class I MHC Molecules Involves Post-Golgi Peptide Exchange Influenced by Peptide-MHC Complex Stability and Acidic pH

C. Harding, P. Chefalo, 2003, The Journal of Immunology.

LymphocytesPathway for Presentation of Peptides to T an Alternate Class I MHC Processing Neutrophils Process Exogenous Bacteria Via

C. Harding, N. Potter, 2001 .

Class II antigen processing: analysis of compartments and functions.

C. Harding, 1996, Critical reviews in immunology.

CpG‐B ODNs potently induce low levels of IFN‐αβ and induce IFN‐αβ‐dependent MHC‐I cross‐presentation in DCs as effectively as CpG‐A and CpG‐C ODNs

C. Harding, J. Kuchtey, R. Gray, 2007 .

Processing of exogenous liposome-encapsulated antigens in vivo generates class I MHC-restricted T cell responses.

C. Harding, K. Findlay, D. Collins, 1992, Journal of immunology.

Tight junctions in the lens epithelia of human and frog: freeze-fracture and protein tracer studies.

C. Harding, W. Lo, 1983, Investigative ophthalmology & visual science.

Functional and ultrastructural evidence for intracellular formation of major histocompatibility complex class II-peptide complexes during antigen processing.

E. Unanue, J. Slot, H. Geuze, 1990, Proceedings of the National Academy of Sciences of the United States of America.

Antigen Processing and Presentation

C. Harding, 2007 .

Antigen Processing and Presentation

C. Harding, 2000 .

Osteocytes directly regulate osteolysis via MYD88 signaling in bacterial bone infection

L. Bonewald, C. Harding, R. Rojas, 2022, Nature Communications.

Interferon-α Is the Primary Plasma Type-I IFN in HIV-1 Infection and Correlates with Immune Activation and Disease Markers

M. Lederman, R. Rabin, T. Schacker, 2013, PloS one.

Desensitization to type I interferon in HIV-1 infection correlates with markers of immune activation and disease progression.

M. Lederman, C. Harding, S. Sieg, 2009, Blood.

Interferon-α differentially rescues CD4 and CD8 T cells from apoptosis in HIV infection

M. Lederman, C. Harding, S. Sieg, 2006 .

Regulation of Antigen Presenting Cell Function by CpG DNA

C. Harding, D. Askew, R. Chu, 2002 .

Techniques for studying phagocytic processing of bacteria for class I or II MHC-restricted antigen recognition by T lymphocytes.

C. Harding, 1994, Methods in cell biology.

Modulation of Naive CD4+ T-Cell Responses to an Airway Antigen during Pulmonary Mycobacterial Infection

C. Harding, W. Boom, Mursalin M. Anis, 2007, Infection and Immunity.

Modulation of Naive CD4 (cid:1) T-Cell Responses to an Airway Antigen during Pulmonary Mycobacterial Infection (cid:1)

C. Harding, W. Boom, Mursalin M. Anis, 2007 .

TLR2 on CD4+ and CD8+ T cells promotes late control of Mycobacterium tuberculosis infection

C. Harding, R. Rojas, W. Boom, 2021, bioRxiv.

TLR2 engagement on CD4+ T cells enhances effector functions and protective responses to Mycobacterium tuberculosis

A. F. Karim, Xuedong Ding, C. Harding, 2014, European journal of immunology.

Innate Immunity and APC Function Lipoprotein Agonist of TLR2 That Regulates LprA Is a Mycobacterium tuberculosis

C. Harding, A. Gehring, N. Pecora, 2006 .

Flow analysis of MHC molecules and other membrane proteins in isolated phagosomes.

C. Harding, W. Boom, D. Canaday, 1998, Journal of immunological methods.

Antigen processing and recognition Editorial overview

J. Neefjes, C. Harding, 2005 .

gp96 leads the way for toll-like receptors.

C. Harding, 2007, Immunity.

Processing and presentation of intact hen egg‐white lysozyme by dendritic cells

C. Harding, J. Nieland, M. De Bruijn, 1992, European journal of immunology.

TLR9 stimulation drives naïve B cells to proliferate and to attain enhanced antigen presenting function

M. Lederman, C. Harding, S. Sieg, 2007, European journal of immunology.

CpG Oligodeoxynucleotides Act as Adjuvants for Pneumococcal Polysaccharide-Protein Conjugate Vaccines and Enhance Antipolysaccharide Immunoglobulin G2a (IgG2a) and IgG3 Antibodies

N. Greenspan, C. Harding, J. Schreiber, 2000, Infection and Immunity.

Mycobacterium tuberculosis Membrane Vesicles Inhibit T Cell Activation

O. J. Sande, C. Harding, R. Rojas, 2017, The Journal of Immunology.

A carbohydrate antigen linked to a T-cell immunogenic peptide induces T-cell clones selective for carbohydrate

E. Unanue, J. Kihlberg, C. Harding, 1993 .

Responsiveness to IL-7 but not to IFN-&agr; is diminished in CD4+ T cells from treated HIV infected patients who experience poor CD4+ T-cell recovery

M. Lederman, C. Harding, S. Sieg, 2016, AIDS.

Modulation of Pulmonary Dendritic Cell Function during Mycobacterial Infection

C. Harding, W. Boom, Yi C. Liu, 2007, Infection and Immunity.

The control of cell division in the ocular lens.

C. Harding, M. Bagchi, J. Reddan, 1971, International review of cytology.

Mycobacterium bovis BCG decreases MHC-II expression in vivo on murine lung macrophages and dendritic cells during aerosol infection.

C. Harding, W. Boom, M. Drage, 2009, Cellular immunology.

Exosomes derived from HIV-1-infected cells promote growth and progression of cancer via HIV TAR RNA

J. Karn, C. Harding, S. Sieg, 2018, Nature Communications.

CpG Oligodeoxynucleotides Act as Adjuvants that Switch on T Helper 1 (Th1) Immunity

C. Harding, P. Lehmann, A. Krieg, 1997, The Journal of experimental medicine.

Differential Expression of Interleukin-2 and Gamma Interferon in Human Immunodeficiency Virus Disease

M. Lederman, C. Harding, S. Sieg, 2001, Journal of Virology.

In vitro human memory CD8 T cell expansion in response to cytomegalovirus requires CD4+ T cell help.

M. Lederman, C. Harding, S. Sieg, 2004, Journal of Infectious Diseases.

CELLULAR PROLIFERATION IN THE LENS.

B. D. Srinivasan, C. Harding, 1965, Investigative ophthalmology.

Disappearance of Tritiated Thymidine and Tritiated Water from the Anterior Chamber of the Rabbit Eye

C. Harding, R. Maenza, RONALD M. MAENZA, 1962, Nature.

Tritium Retention by Corneal Endothelium After Incorporation of H3—Thymidine

C. Harding, L. Bito, 1961 .

P2X7 Receptor-Stimulated Secretion of MHC Class II-Containing Exosomes Requires the ASC/NLRP3 Inflammasome but Is Independent of Caspase-1 1

S. Mohr, G. Dubyak, G. Núñez, 2009, The Journal of Immunology.

Induction of mitosis in the cultured rabbit lens initiated by the addition of insulin to medium KEI-4.

C. Harding, M. Bagchi, J. Reddan, 1975, Experimental eye research.

DNA SYNTHESIS AND CELL DIVISION IN THE CULTURED OCULAR LENS.

C. Harding, M. N. Thayer, 1964, Investigative ophthalmology.

The activation of DNA synthesis and cell division in rabbit lens in vitro.

C. Harding, M. Newman, H. Rothstein, 1962, Experimental eye research.

Autoradiographic localization of tritiated thymidine in wholemount preparations of lens epithelium.

V. Bond, C. Harding, W. Hughes, 1960, Archives of ophthalmology.

CpG oligodeoxynucleotides down-regulate macrophage class II MHC antigen processing.

C. Harding, A. Tobian, A. Krieg, 1999, Journal of immunology.

SARS-CoV-2 and ACE2: The biology and clinical data settling the ARB and ACEI controversy

M. Chung, M. Lederman, A. Schmaier, 2020, EBioMedicine.

Seasonal mitotic activity and wound healing in a teleost (Opsanus tau) ocular lens

C. Harding, J. Reddan, C. Mathews, 1975, Experientia.

Epithelial cell surfaces and the basement membrane in the ocular lens, studied with the scanning electron microscope.

C. Harding, T. Kuwabara, M. Bagchi, 1973, Experimental eye research.

Characterization of macromolecular synthesis in the epithelium of cultured rabbit lenses.

C. Harding, J. Reddan, M. W. Crotty, 1970, Experimental eye research.

An enzymatic assay for DNA in epoxy-tissue-sections by light microscope-autoradiography.

C. Harding, J. Reddan, N. Unakar, 1973, Experimental cell research.

INCORPORATION OF IDOXURIDINE (IDU) BY THE RABBIT LENS EPITHELIUM IN VITRO.

C. Harding, W. Hughes, M. B. Wheeler, 1964, A M A Archives of Ophthalmology.

DEVELOPMENTAL CHANGES IN THE INCORPORATION OF 5-IODO-DEOXYURIDINE BY THE EMBRYO OF ARBACIA PUNCTULATA.

C. Harding, W. Hughes, W. Wilson, 1964, Experimental Cell Research.

B lymphocytes secrete antigen-presenting vesicles

C. Melief, H. Geuze, W. Stoorvogel, 1996, The Journal of experimental medicine.

Mannose-Capped Lipoarabinomannan from Mycobacterium tuberculosis Induces CD4+ T Cell Anergy via GRAIL

A. F. Karim, O. J. Sande, Xuedong Ding, 2016, The Journal of Immunology.

Inhibition of IFN-γ-Induced Class II Transactivator Expression by a 19-kDa Lipoprotein from Mycobacterium tuberculosis: A Potential Mechanism for Immune Evasion1

C. Harding, W. Boom, T. Hamilton, 2003, The Journal of Immunology.

Extracellular vesicles and infectious diseases: new complexity to an old story.

C. Harding, J. Schorey, 2016, The Journal of clinical investigation.

Exosomes: Looking back three decades and into the future

C. Harding, P. Stahl, J. Heuser, 2013, The Journal of cell biology.

Macrophage Class II MHC Antigen A Novel TLR-2 Ligand That Inhibits Human ) : Rv 1411 c LprG ( Mycobacterium tuberculosis

J. Belisle, C. Harding, W. Boom, 2004 .

Differential Effects of Hepatitis C Virus JFH1 on Human Myeloid and Plasmacytoid Dendritic Cells

D. Anthony, C. Harding, B. Rodriguez, 2009, Journal of Virology.

Activation of Human CD8+ αβ TCR+ Cells by Mycobacterium tuberculosis Via an Alternate Class I MHC Antigen-Processing Pathway

C. Harding, W. Boom, D. Canaday, 1999, The Journal of Immunology.

Deficiency of transporter for antigen presentation (TAP) in tumor cells allows evasion of immune surveillance and increases tumorigenesis.

D. Templeton, M. Sy, C. Harding, 1999, Journal of immunology.

Roles of proteasomes, transporter for antigen presentation (TAP), and beta 2-microglobulin in the processing of bacterial or particulate antigens via an alternate class I MHC processing pathway.

C. Harding, R. Song, Clifford V. Harding, 1996, Journal of immunology.

Determinants of protection among HIV‐exposed seronegative persons: an overview.

D. Goldstein, J. Goedert, M. Lederman, 2010, The Journal of infectious diseases.

CCAAT/Enhancer-Binding Protein and Binding to CIITA Promoters Is Associated with the Inhibition of CIITA Expression in Response to Mycobacterium tuberculosis 19-kDa Lipoprotein

Jianqi Yang, C. Harding, W. Boom, 2007 .

CpG-B Oligodeoxynucleotides Inhibit TLR-Dependent and -Independent Induction of Type I IFN in Dendritic Cells

Clifford V. Harding, Derek W. Abbott, C. Harding, 2010, The Journal of Immunology.

Prolonged Toll-Like Receptor Signaling by Mycobacterium tuberculosis and Its 19-Kilodalton Lipoprotein Inhibits Gamma Interferon-Induced Regulation of Selected Genes in Macrophages

C. Harding, W. Boom, A. Tobian, 2004, Infection and Immunity.

The Mycobacterium tuberculosis 19-Kilodalton Lipoprotein Inhibits Gamma Interferon-Regulated HLA-DR and FcγR1 on Human Macrophages through Toll-Like Receptor 2

C. Harding, R. Rojas, W. Boom, 2003, Infection and Immunity.

Regulation of Class II MHC Expression in APCs: Roles of Types I, III, and IV Class II Transactivator1

C. Harding, W. Boom, D. Askew, 2002, The Journal of Immunology.

Surface ultrastructure of the cornea and adjacent epidermis during metamorphosis of Rana pipiens A scanning electron microscopic study

C. Harding, J. Kaltenbach, Stanley Susan, 1980, Journal of morphology.

Cross fertilization with the sperm of Arbacia lixula

C. Harding, D. Harding, 1952 .

Stimulation of Mitosis in the Vertebrate Lens in the Presence of Insulin

C. Harding, J. Reddan, H. Rothstein, 1972 .

Incorporation of thymidine by injured lens epithelium.

B. D. Srinivasan, C. Harding, A. Donn, 1959, Experimental cell research.

Patterns of cellular organization and cell division in the epithelium of the cultured lens.

C. Harding, L. Bito, 1965, Experimental eye research.

The action of certain polysaccharides on fertilization in the sea urchin egg

C. Harding, 1951 .

The nuclear envelope in the crystalline lens fiber cell.

C. Harding, S. Susan, 1976, Investigative Ophthalmology.

Scanning Electron Microscopy of the Adult Rabbit Lens

C. Harding, S. Susan, Hedwig Murphy, 1976 .

SEMIPERMEABILITY OF THE NUCLEAR MEMBRANE IN THE INTACT CELL

C. Harding, C. Feldherr, 1959, The Journal of general physiology.

Quantitative studies on the stimulation of mitosis and DNA synthesis in the cultured rabbit ocular lens.

J. Wilson, C. Harding, W. Wilson, 1967, Experimental eye research.

Human β-defensin-3 activates professional antigen-presenting cells via Toll-like receptors 1 and 2

M. Lederman, C. Harding, S. Sieg, 2007, Proceedings of the National Academy of Sciences.

Inhibition of macropinocytosis blocks antigen presentation of type II collagen in vitro and in vivo in HLA-DR1 transgenic mice

J. Isaacs, R. Holmdahl, D. Altmann, 2006, Arthritis research & therapy.

Mouse Endothelial Cells Cross-Present Lymphocyte-Derived Antigen on Class I MHC via a TAP1- and Proteasome-Dependent Pathway1

C. Harding, A. Valujskikh, P. Heeger, 2005, The Journal of Immunology.

Interferon‐α inhibits CD4 T cell responses to interleukin‐7 and interleukin‐2 and selectively interferes with Akt signaling

M. Lederman, C. Harding, S. Sieg, 2015, Journal of leukocyte biology.

Impaired T-cell responses to sphingosine-1-phosphate in HIV-1 infected lymph nodes.

M. Lederman, T. Schacker, E. Haddad, 2013, Blood.

Intracellular signalling cascades regulating innate immune responses to Mycobacteria: branching out from Toll‐like receptors

Chul Hee Choi, C. Harding, Chul-Su Yang, 2007, Cellular microbiology.

Guidance for Rebooting Electrophysiology Through the COVID-19 Pandemic From the Heart Rhythm Society and the American Heart Association Electrocardiography and Arrhythmias Committee of the Council on Clinical Cardiology

Dhanunjaya R. Lakkireddy, Paul J. Wang, M. Chung, 2020, Circulation. Arrhythmia and electrophysiology.

MyD88-dependent interplay between myeloid and endothelial cells in the initiation and progression of obesity-associated inflammatory diseases

S. Hazen, R. Ransohoff, Jonathan D. Smith, 2014, The Journal of experimental medicine.

Systemic deficits in transporter for antigen presentation (TAP)‐1 or proteasome subunit LMP2 have little or no effect on tumor incidence

F. Abdul-Karim, M. Sy, C. Harding, 2001, International journal of cancer.

HIV-1 infection impairs cell cycle progression of CD4(+) T cells without affecting early activation responses.

M. Lederman, C. Harding, S. Sieg, 2001, The Journal of clinical investigation.

CpG DNA Induces a Class II Transactivator-Independent Increase in Class II MHC by Stabilizing Class II MHC mRNA in B Lymphocytes 1

C. Harding, J. Kuchtey, R. Pai, 2003, The Journal of Immunology.

: A Potential Mechanism for Immune Evasion Mycobacterium tuberculosis Lipoprotein from Transactivator Expression by a 19-kDa -Induced Class II g Inhibition of IFN-Henry

C. Harding, W. Boom, T. Hamilton, 2003 .

Interferon-alpha differentially rescues CD4 and CD8 T cells from apoptosis in HIV infection.

M. Lederman, C. Harding, S. Sieg, 2006, AIDS.

Impaired Monocyte Maturation in Response to CpG Oligodeoxynucleotide Is Related to Viral RNA Levels in Human Immunodeficiency Virus Disease and Is at Least Partially Mediated by Deficiencies in Alpha/Beta Interferon Responsiveness and Production

M. Lederman, C. Harding, S. Sieg, 2005, Journal of Virology.

Upregulation of Local Hepcidin Contributes to Iron Accumulation in Alzheimer's Disease Brains.

C. Harding, Neena Singh, S. Chaudhary, 2021, Journal of Alzheimer's disease : JAD.

Mycobacterium tuberculosis and TLR2 Agonists Inhibit Induction of Type I IFN and Class I MHC Antigen Cross Processing by TLR9

C. Harding, W. Boom, D. Canaday, 2010, The Journal of Immunology.

Induction of mitosis in ocular tissue by chemotoxic agents.

C. Harding, R. Briggs, J. Reddan, 1975, Experimental eye research.

Antigen processing and intracellular traffic of antigens and MHC molecules.

H. Geuze, C. Harding, 1993, Current opinion in cell biology.

Novel dipeptide aldehydes are proteasome inhibitors and block the MHC-I antigen-processing pathway.

C. Harding, S. Chatterjee, R. Siman, 1995, Journal of immunology.

Thermolabile H-2Kb molecules expressed by transporter associated with antigen processing-deficient RMA-S cells are occupied by low-affinity peptides.

E. Harhaj, C. Harding, S. Joyce, 1999, Journal of immunology.

Occupied by Low-Affinity Peptides Processing-Deficient RMAS Cells Are Transporter Associated with Antigen Molecules Expressed bybThermolabile H-2 K

E. Harhaj, C. Harding, S. Joyce, 1999 .

Type I IFN and Stabilization of Class I MHC Cross-Presentation by CpG DNA Involves Enhancement of Dendritic Cell Antigen

C. Harding, P. Chefalo, J. Kuchtey, 2005 .

Evasion of Immune Surveillance and Presentation (TAP) in Tumor Cells Allows Deficiency of Transporter for Antigen

D. Templeton, C. Harding, A. Johnsen, 2013 .

Enhancement of Dendritic Cell Antigen Cross-Presentation by CpG DNA Involves Type I IFN and Stabilization of Class I MHC mRNA1

C. Harding, P. Chefalo, J. Kuchtey, 2005, The Journal of Immunology.

Mycobacterium tuberculosis 19-kDa Lipoprotein Promotes Neutrophil Activation1

C. Harding, W. Boom, C. Neufert, 2001, The Journal of Immunology.

TLR9 Class I MHC Antigen Cross Processing by Agonists Inhibit Induction of Type I IFN and and TLR2 Mycobacterium tuberculosis

C. Harding, W. Boom, D. Canaday, 2010 .

B Cell Development Is Regulated By a-Synuclein, a Key Player In Parkinson’s Disease

C. Harding, H. Meyerson, W. Xiao, 2013 .

ERK Signaling Is Essential for Macrophage Development

G. Landreth, C. Harding, W. Boom, 2015, PloS one.

STIMULATION OF DNA SYNTHESIS AND MITOSIS BY INJURY *

B. D. Srinivasan, C. Harding, 1960, Annals of the New York Academy of Sciences.

Novel Quorum-Quenching Agents Promote Methicillin-Resistant Staphylococcus aureus (MRSA) Wound Healing and Sensitize MRSA to β-Lactam Antibiotics

M. Ghannoum, M. Shoham, C. Harding, 2014, Antimicrobial Agents and Chemotherapy.

Electron microscopy of cultured mammalian lenses. I. Initial changes which precede and accompany the stimulation of DNA synthesis and mitosis.

R. Bell, C. Harding, J. Reddan, 1970, Investigative Ophthalmology.

CELLULAR PROLIFERATION AND REGENERATION FOLLOWING TISSUE DAMAGE.

C. Harding, 1972 .

Mycobacterium tuberculosis Synergizes with ATP To Induce Release of Microvesicles and Exosomes Containing Major Histocompatibility Complex Class II Molecules Capable of Antigen Presentation

G. Dubyak, K. Takatsu, C. Harding, 2010, Infection and Immunity.

COVID-19 and Cardiovascular Disease

J. Loscalzo, C. Harding, E. Tsai, 2021, Circulation research.

Genetically associated CD16(+)56(-) natural killer cell interferon (IFN)-αR expression regulates signaling and is implicated in IFN-α-induced hepatitis C virus decline.

D. Anthony, R. Blanton, C. Harding, 2012, The Journal of infectious diseases.

The phoP locus influences processing and presentation of Salmonella typhimurium antigens by activated macrophages

J. Pfeifer, S. Normark, C. Harding, 1995, Molecular microbiology.

Dhanunjaya R. Lakkireddy, Paul J. Wang, M. Chung, 2020, JACC: Clinical Electrophysiology.

Guidance for rebooting electrophysiology through the COVID-19 pandemic from the Heart Rhythm Society and the American Heart Association Electrocardiography and Arrhythmias Committee of the Council on Clinical Cardiology

Dhanunjaya R. Lakkireddy, Paul J. Wang, M. Chung, 2020, Heart Rhythm.

Unit Membrane Redundancy in Spherical Structures Within the Ocular Lens

R. Jampel, C. Harding, S. Susan, 1978 .

Square arrays and their role in ridge formation in human lens fibers.

C. Harding, W. Lo, Woo-Kuen Lo, 1984, Journal of ultrastructure research.

Experimental Modification of the Temporal Aspects of the Serum-Induced Cell Cycle in the Cultured Adult Rabbit Lens

C. Harding, M. Bagchi, J. Reddan, 1971 .

Antigens in sea urchin hybrid embryos.

C. Harding, P. Perlmann, D. Harding, 1954, Experimental cell research.

Impaired Naive and Memory B-Cell Responsiveness to TLR9 Stimulation in Human Immunodeficiency Virus Infection

M. Lederman, C. Harding, S. Sieg, 2008, Journal of Virology.

Late stages of hematopoiesis and B cell lymphopoiesis are regulated by α-synuclein, a key player in Parkinson's disease.

C. Harding, H. Meyerson, W. Xiao, 2014, Immunobiology.

Injury-induced Synthesis of Deoxyribonucleic Acid in the Lens of the Sea Bass

C. Harding, H. Rothstein, 1962, Nature.

Processing of bacterial antigens for presentation to class I and II MHC-restricted T lymphocytes.

H. Geuze, J. Pfeifer, C. Harding, 1995, Infectious agents and disease.

Interferon‐αβ mediates partial control of early pulmonary Mycobacterium bovis bacillus Calmette–Guérin infection

C. Harding, W. Boom, J. Kuchtey, 2006 .

The Nuclear Membrane and Nucleocytoplasmic Interchange

A. Mirsky, W. Loewenstein, J. Gall, 1964, Protoplasmatologia.

The NQR complex regulates the immunomodulatory function of Bacteroides thetaiotaomicron

C. Harding, Philip P. Ahern, E. Martens, 2023, bioRxiv.

Interferon-Alpha Administration Enhances CD8+ T Cell Activation in HIV Infection

R. Schooley, M. Lederman, D. Asmuth, 2012, PloS one.

A rapid, automated surface protein profiling of single circulating exosomes in human blood

J. Lötvall, G. Kibria, Simo Huang, 2016, Scientific Reports.

Mycobacterium tuberculosis Interactions with Dendritic Cells and Macrophages

C. Harding, M. Drage, N. Pecora, 2017 .

Exosomes derived from HIV-1-infected cells promote growth and progression of cancer via HIV TAR RNA

J. Karn, C. Harding, S. Sieg, 2018, Nature Communications.

Blockade of Deoxyribonucleic Acid Synthesis by Deuterium Oxide

C. Harding, P. Gross, 1961, Science.

MyD88-dependent interplay between myeloid and endothelial cells in the initiation and progression of obesity-associated inflammatory diseases

R. Ransohoff, Jonathan D. Smith, A. DeFranco, 2014, The Journal of Experimental Medicine.

CpG DNA Induces a Class II Transactivator-Independent Increase in Class II MHC by Stabilizing Class II MHC mRNA in B Lymphocytes

C. Harding, J. Kuchtey, R. Pai, 2003, The Journal of Immunology.

Electroporation of exogenous antigen into the cytosol for antigen processing and class I major histocompatibility complex (MHC) presentation: weak base amines and hypothermia (18°C) inhibit the class I MHC processing pathway

C. Harding, 1992, European journal of immunology.

Antigen-binding function of class II MHC molecules.

E. Unanue, C. Harding, I. Luescher, 1989, Cold Spring Harbor symposia on quantitative biology.

ATP and Control of Intracellular Growth of Mycobacteria by T Cells

G. Dubyak, C. Harding, W. Boom, 2002, Infection and Immunity.

Exosomes: Looking back three decades and into the future

C. Harding, P. Stahl, J. Heuser, 2013, The Journal of Cell Biology.

Localization of peptide/MHC class II complexes in macrophages following antigen processing of viable Streptococcus pyogenes

C. Harding, L. Ramachandra, Alexei von Delwig, 2003, European journal of immunology.

Intracellular organelles involved in antigen processing and the binding of peptides to class II MHC molecules.

C. Harding, 1995, Seminars in immunology.

Mycobacterium tuberculosis Lipoprotein LprG Binds Lipoarabinomannan and Determines Its Cell Envelope Localization to Control Phagolysosomal Fusion

C. Harding, W. Boom, M. Jackson, 2014, PLoS pathogens.

Mycobacterium tuberculosis lipoprotein LprG (Rv1411c) binds triacylated glycolipid agonists of Toll-like receptor 2

J. Sacchettini, D. Moody, C. Harding, 2010, Nature Structural &Molecular Biology.

Structure and distribution of gap junctions in lens epithelium and fiber cells

C. Harding, W. Lo, 2004, Cell and Tissue Research.

Semipermeability of the Nuclear Membrane

C. Harding, C. Feldherr, 1958, Nature.

Transferrin recycling in reticulocytes: pH and iron are important determinants of ligand binding and processing.

C. Harding, P. Stahl, C. Harding, 1983, Biochemical and biophysical research communications.

Development of immune-complex glomerulonephritis in athymic mice: T cells are not required for the genesis of glomerular injury

C. Harding, S. Emancipator, Medhat O. Hassan, 2005, Laboratory Investigation.

Endocytosis and intracellular processing of transferrin and colloidal gold-transferrin in rat reticulocytes: demonstration of a pathway for receptor shedding.

C. Harding, P. Stahl, J. Heuser, 1984, European journal of cell biology.

Phosphatidylinositol mannoside from Mycobacterium tuberculosis binds alpha5beta1 integrin (VLA-5) on CD4+ T cells and induces adhesion to fibronectin.

J. Belisle, C. Harding, R. Rojas, 2006, Journal of immunology.

Low-temperature inhibition of antigen processing and iron uptake from transferrin: deficits in endosome functions at 18 degrees C.

E. Unanue, C. Harding, 1990, European journal of immunology.

Potassium distribution in the normal rat lens

C. Harding, W. Bobrowski, M. Owczarzak, 1986 .

Elemental studies in rat lens during galactose cataract reversal.

C. Harding, W. Bobrowski, N J Unakar, 1993, Current eye research.

Mycobacterial lipoprotein activates autophagy via TLR2/1/CD14 and a functional vitamin D receptor signalling

J. Son, C. Harding, D. Shin, 2010, Cellular microbiology.

B lymphocytes secrete antigen-presenting vesicles

C. Melief, H. Geuze, W. Stoorvogel, 1996, The Journal of experimental medicine.

Class II MHC molecules are present in macrophage lysosomes and phagolysosomes that function in the phagocytic processing of Listeria monocytogenes for presentation to T cells

H. Geuze, C. Harding, 1992, The Journal of cell biology.

Genetically associated CD16(+)56(-) natural killer cell interferon (IFN)-αR expression regulates signaling and is implicated in IFN-α-induced hepatitis C virus decline.

D. Anthony, R. Blanton, C. Harding, 2012, The Journal of infectious diseases.

Ultrastructural changes in peripheral blood leukocytes in α-synuclein knockout mice.

C. Harding, R. Maitta, A. Shameli, 2018, Blood cells, molecules & diseases.

Mycobacterium tuberculosis lipoprotein‐induced association of TLR2 with protein kinase C ζ in lipid rafts contributes to reactive oxygen species‐dependent inflammatory signalling in macrophages

Ji-yeon Lee, C. Harding, Sung Joong Lee, 2008, Cellular microbiology.

Plasmacytoid Dendritic Cells Mediate Synergistic Effects of HIV and Lipopolysaccharide on CD27+ IgD– Memory B Cell Apoptosis

M. Lederman, N. Greenspan, Yong Gao, 2014, Journal of Virology.

Class II MHC antigen processing in phagosomes.

C. Harding, W. Boom, L. Ramachandra, 2008, Methods in molecular biology.

Mycobacterium tuberculosis lipoprotein LprG (Rv1411c) binds triacylated glycolipid agonists of Toll-like receptor 2

J. Sacchettini, C. Harding, R. Rojas, 2010, Nature Structural &Molecular Biology.

Interferon-alphabeta mediates partial control of early pulmonary Mycobacterium bovis bacillus Calmette-Guérin infection.

C. Harding, W. Boom, J. Kuchtey, 2006, Immunology.

Ultraviolet light induced delay in cleavage of centrifuged Arbacia eggs.

C. Harding, L. J. Thomas, 1950, Journal of cellular and comparative physiology.

Antigen Processing and Presentation

C. Harding, 2007, Computational Immunology.