J. Boccard

P. Carrupt, S. Rudaz, F. Bajot, 2009, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Metabolite profiling of plant extracts by ultra-high-pressure liquid chromatography at elevated temperature coupled to time-of-flight mass spectrometry.

Serge Rudaz, Davy Guillarme, Julien Boccard, 2009, Journal of chromatography. A.

Protein pathway analysis to study development-dependent effects of acute and repeated trimethyltin (TMT) treatments in 3D rat brain cell cultures.

S. Rudaz, Jean-Charles Sanchez, J. Boccard, 2019, Toxicology in vitro : an international journal published in association with BIBRA.

Statistical Correlations between HPLC Activity-Based Profiling Results and NMR/MS Microfraction Data to Deconvolute Bioactive Compounds in Mixtures

Serge Rudaz, Julien Boccard, Jean-Luc Wolfender, 2016, Molecules.

Cultivar, site or harvest date: the gordian knot of wine terroir

J. Blackman, J. Boccard, L. Schmidtke, 2020, Metabolomics.

Removal of batch effects using stratified subsampling of metabolomic data for in vitro endocrine disruptors screening.

S. Rudaz, A. Odermatt, J. Boccard, 2019, Talanta.

Exploring Omics data from designed experiments using analysis of variance multiblock Orthogonal Partial Least Squares.

Serge Rudaz, Julien Boccard, S. Rudaz, 2016, Analytica chimica acta.

Comprehensive profiling and marker identification in non-volatile citrus oil residues by mass spectrometry and nuclear magnetic resonance.

S. Rudaz, L. Marcourt, J. Boccard, 2014, Food chemistry.

Metabolomics: Application in Plant Sciences

S. Rudaz, G. Glauser, J. Boccard, 2013 .

Combining the advantages of multilevel and orthogonal partial least squares data analysis for longitudinal metabolomics: Application to kidney transplantation.

P. Lescuyer, S. Rudaz, B. Ponte, 2020, Analytica chimica acta.

Enhanced metabolite annotation via dynamic retention time prediction: Steroidogenesis alterations as a case study.

Serge Rudaz, Ioannis Xenarios, Julien Boccard, 2017, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Implementation of liquid chromatography-high resolution mass spectrometry methods for untargeted metabolomic analyses of biological samples: A tutorial.

Serge Rudaz, Julien Boccard, Víctor González-Ruiz, 2020, Analytica chimica acta.

Steroidomics for highlighting novel serum biomarkers of testosterone doping.

S. Rudaz, M. Saugy, J. Boccard, 2019, Bioanalysis.

A scoring approach for multi-platform acquisition in metabolomics.

S. Rudaz, D. Guillarme, J. Boccard, 2019, Journal of chromatography. A.

Steroid profile analysis by LC-HRMS in human seminal fluid.

S. Rudaz, J. Boccard, R. Rahban, 2019, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Steroid profiles in both blood serum and seminal plasma are not correlated and do not reflect sperm quality: Study on the male reproductive health of fifty young Swiss men.

S. Rudaz, J. Boccard, R. Rahban, 2018, Clinical biochemistry.

UHPLC-HRMS Analysis for Steroid Profiling in Serum (Steroidomics).

S. Rudaz, M. Saugy, J. Boccard, 2018, Methods in molecular biology.

Quantification of glucuronidated and sulfated steroids in human urine by ultra-high pressure liquid chromatography quadrupole time-of-flight mass spectrometry

J. Veuthey, S. Rudaz, M. Saugy, 2011, Analytical and bioanalytical chemistry.

Steroidomic Footprinting Based on Ultra-High Performance Liquid Chromatography Coupled with Qualitative and Quantitative High-Resolution Mass Spectrometry for the Evaluation of Endocrine Disrupting Chemicals in H295R Cells.

D. Hochstrasser, S. Rudaz, A. Odermatt, 2015, Chemical research in toxicology.

Steroid profiling in H295R cells to identify chemicals potentially disrupting the production of adrenal steroids.

S. Rudaz, A. Odermatt, D. Kratschmar, 2017, Toxicology.

Choosing an Optimal Sample Preparation in Caulobacter crescentus for Untargeted Metabolomics Approaches

S. Rudaz, J. Boccard, Julian Pezzatti, 2019, Metabolites.

Retention time prediction for dereplication of natural products (CxHyOz) in LC-MS metabolite profiling.

P. Carrupt, J. Boccard, Philippe J. Eugster, 2014, Phytochemistry.

Inhibition of enteric methanogenesis in dairy cows induces changes in plasma metabolome highlighting metabolic shifts and potential markers of emission

F. Jourdan, C. Canlet, J. Boccard, 2020, Scientific Reports.

Supercritical fluid chromatography-mass spectrometry in routine anti-doping analyses: Estimation of retention time variability under reproducible conditions.

J. Veuthey, S. Rudaz, D. Guillarme, 2019, Journal of chromatography. A.

Method development for pharmaceutics: some solutions for tuning selectivity in reversed phase and hydrophilic interaction liquid chromatography.

J. Veuthey, S. Rudaz, D. Guillarme, 2012, Journal of pharmaceutical and biomedical analysis.

Exploring blood alterations in chronic kidney disease and haemodialysis using metabolomics

S. Rudaz, S. de Seigneux, B. Ponte, 2020, Scientific Reports.

Integrating metabolomic data from multiple analytical platforms for a comprehensive characterisation of lemon essential oils

S. Rudaz, J. Boccard, J. Wolfender, 2015 .

Optimized selection of liquid chromatography conditions for wide range analysis of natural compounds.

J. Veuthey, A. Periat, D. Guillarme, 2017, Journal of chromatography. A.

Systematic comparison of sensitivity between hydrophilic interaction liquid chromatography and reversed phase liquid chromatography coupled with mass spectrometry.

J. Veuthey, S. Rudaz, A. Periat, 2013, Journal of chromatography. A.

Insights on the Structural and Metabolic Resistance of Potato (Solanum tuberosum) Cultivars to Tuber Black Dot (Colletotrichum coccodes)

K. Gindro, J. Boccard, J. Wolfender, 2020, Frontiers in Plant Science.

Systematic evaluation of matrix effects in hydrophilic interaction chromatography versus reversed phase liquid chromatography coupled to mass spectrometry.

J. Veuthey, A. Periat, D. Guillarme, 2016, Journal of chromatography. A.

Comprehensive Examination of the Mouse Lung Metabolome Following Mycobacterium tuberculosis Infection Using a Multiplatform Mass Spectrometry Approach

S. Rudaz, A. Steyn, C. Barbas, 2020, Journal of proteome research.

Evaluation and identification of dioxin exposure biomarkers in human urine by high-resolution metabolomics, multivariate analysis and in vitro synthesis.

D. Hochstrasser, J. Saurat, S. Rudaz, 2016, Toxicology letters.

In vitro models to study insulin and glucocorticoids modulation of trimethyltin (TMT)-induced neuroinflammation and neurodegeneration, and in vivo validation in db/db mice

O. Poirot, A. Odermatt, B. Chantong, 2019, Archives of Toxicology.

DISCOVER WILEY'S LEADING STATISTICS JOURNALS

Concha Bielza, Pedro Larrañaga, Serge Rudaz, 2014 .

From raw signals to identified metabolites: recent tools for enhancing LC–MS untargeted metabolomic data processing

S. Rudaz, J. Boccard, D. Tonoli, 2015 .

Profiling of steroid metabolites after transdermal and oral administration of testosterone by ultra-high pressure liquid chromatography coupled to quadrupole time-of-flight mass spectrometry

N. Baume, J. Boccard, F. Badoud, 2013, The Journal of Steroid Biochemistry and Molecular Biology.

Dynamics of Metabolite Induction in Fungal Co-cultures by Metabolomics at Both Volatile and Non-volatile Levels

S. Rudaz, K. Gindro, J. Boccard, 2018, Front. Microbiol..

An integrated metabolomics and proteogenomics approach reveals molecular alterations following carbamazepine exposure in the male mussel Mytilus galloprovincialis.

J. Armengaud, J. Boccard, F. Courant, 2021, Chemosphere.

Digoxin Induces Human Astrocyte Reaction In Vitro

Jean-Charles Sanchez, J. Boccard, Víctor González-Ruiz, 2022, Molecular neurobiology.

Development and validation of an UHPLC-MS/MS method for extended serum steroid profiling in female populations.

S. Rudaz, M. Saugy, J. Boccard, 2020, Bioanalysis.

Wipe-sampling procedure optimisation for the determination of 23 antineoplastic drugs used in the hospital pharmacy

S. Rudaz, P. Bonnabry, J. Boccard, 2019, European journal of hospital pharmacy : science and practice.

In vitro models to study insulin and glucocorticoids modulation of trimethyltin (TMT)-induced neuroinflammation and neurodegeneration, and in vivo validation in db/db mice

O. Poirot, A. Odermatt, B. Chantong, 2019, Archives of Toxicology.

Applicability of Supercritical fluid chromatography-Mass spectrometry to metabolomics. II-Assessment of a comprehensive library of metabolites and evaluation of biological matrices.

J. Veuthey, S. Rudaz, D. Guillarme, 2020, Journal of chromatography. A.

An Integrative Multi-Omics Workflow to Address Multifactorial Toxicology Experiments

Serge Rudaz, Jenny Sandström, Julien Boccard, 2019, Metabolites.

From fundamentals in calibration to modern methodologies: A tutorial for small molecules quantification in liquid chromatography-mass spectrometry bioanalysis.

S. Rudaz, M. Feinberg, J. Boccard, 2022, Analytica chimica acta.

Differentiation of lemon essential oil based on volatile and non-volatile fractions with various analytical techniques: a metabolomic approach.

S. Rudaz, M. Velazco, J. Boccard, 2014, Food chemistry.

Mass spectrometry metabolomic data handling for biomarker discovery

Serge Rudaz, Julien Boccard, S. Rudaz, 2020, Proteomic and Metabolomic Approaches to Biomarker Discovery.

Standard machine learning algorithms applied to UPLC-TOF/MS metabolic fingerprinting for the discovery of wound biomarkers in Arabidopsis thaliana

Melanie Hilario, Alexandros Kalousis, Julien Boccard, 2010 .

Knowledge discovery in metabolomics: an overview of MS data handling.

Serge Rudaz, Julien Boccard, Jean-Luc Veuthey, 2010, Journal of separation science.

Antimitotic and antiproliferative activities of chalcones: forward structure-activity relationship.

P. Carrupt, E. Matera, C. Dumontet, 2008, Journal of medicinal chemistry.

Breast cancer resistance protein (BCRP/ABCG2): new inhibitors and QSAR studies by a 3D linear solvation energy approach.

Julien Boccard, Pierre-Alain Carrupt, P. Carrupt, 2009, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

MS-based Plant Metabolomic Approaches for Biomarker Discovery

S. Rudaz, G. Glauser, J. Boccard, 2009, Natural product communications.

Standardized LC×LC-ELSD Fractionation Procedure for the Identification of Minor Bioactives via the Enzymatic Screening of Natural Extracts.

D. Barron, K. Sakamoto, M. Deák, 2016, Journal of natural products.

Multifactorial Analysis of Environmental Metabolomic Data in Ecotoxicology: Wild Marine Mussel Exposed to WWTP Effluent as a Case Study

J. Boccard, F. Courant, H. Fenet, 2020, Metabolites.

Metabotypes of Pseudomonas aeruginosa Correlate with Antibiotic Resistance, Virulence and Clinical Outcome in Cystic Fibrosis Chronic Infections

J. Boccard, D. Bicout, F. Fenaille, 2021, Metabolites.

Metabolomics approach reveals disruption of metabolic pathways in the marine bivalve Mytilus galloprovincialis exposed to a WWTP effluent extract.

J. Boccard, F. Courant, H. Fenet, 2020, The Science of the total environment.

Approaches in metabolomics for regulatory toxicology applications.

S. Rudaz, J. Boccard, Víctor González-Ruiz, 2021, The Analyst.

Methods for Doping Detection.

S. Rudaz, N. Baume, M. Saugy, 2016, Frontiers of hormone research.

Targeted metabolomics shows plasticity in the evolution of signaling lipids and uncovers old and new endocannabinoids in the plant kingdom

A. Schubert, J. Gertsch, J. Boccard, 2017, Scientific Reports.

Rumen microbial communities influence metabolic phenotypes in lambs

Julien Boccard, Estelle Rathahao-Paris, Hamid Boudra, 2015, Front. Microbiol..

Metabolomic analysis of urine samples by UHPLC-QTOF-MS: Impact of normalization strategies.

Serge Rudaz, Julie Schappler, Julien Boccard, 2017, Analytica chimica acta.

Structured plant metabolomics for the simultaneous exploration of multiple factors

Julien Boccard, Serge Rudaz, Nikolay Vasilev, 2016, Scientific Reports.

Phenotypic and molecular characterization of proliferating and differentiated GnRH-expressing GnV-3 cells

J. Boccard, V. Prévot, F. Pralong, 2011, Molecular and Cellular Endocrinology.

Human urinary biomarkers of dioxin exposure: analysis by metabolomics and biologically driven data dimensionality reduction.

D. Hochstrasser, J. Saurat, S. Rudaz, 2014, Toxicology letters.

Analysis of basic compounds by supercritical fluid chromatography: attempts to improve peak shape and maintain mass spectrometry compatibility.

Davy Guillarme, Julien Boccard, Jean-Luc Veuthey, 2012, Journal of chromatography. A.

Analytical aspects in doping control: challenges and perspectives.

Serge Rudaz, Martial Saugy, Davy Guillarme, 2011, Forensic science international.

Neuroinflammatory Response to TNFα and IL1β Cytokines Is Accompanied by an Increase in Glycolysis in Human Astrocytes In Vitro

S. Rudaz, L. Pellerin, Jean-Charles Sanchez, 2021, International journal of molecular sciences.

CD40-CD40 ligand disruption does not prevent hyperoxia-induced injury.

J. Boccard, Y. Donati, C. Vesin, 2002, The American journal of pathology.

Evaluation of steroidomics by liquid chromatography hyphenated to mass spectrometry as a powerful analytical strategy for measuring human steroid perturbations.

Serge Rudaz, Martial Saugy, Julien Boccard, 2016, Journal of chromatography. A.

From a single steroid to the steroidome: Trends and analytical challenges

Serge Rudaz, Julien Boccard, Eulalia Olesti, 2020, The Journal of Steroid Biochemistry and Molecular Biology.

Steroid profiling by UHPLC-MS/MS in dried blood spots collected from healthy women with and without testosterone gel administration.

S. Rudaz, M. Saugy, J. Boccard, 2021, Journal of pharmaceutical and biomedical analysis.

Network principal component analysis: a versatile tool for the investigation of multigroup and multiblock datasets

Serge Rudaz, Julien Boccard, Víctor González-Ruiz, 2020, Bioinform..

Optimized liquid chromatography-mass spectrometry approach for the isolation of minor stress biomarkers in plant extracts and their identification by capillary nuclear magnetic resonance.

Serge Rudaz, Davy Guillarme, Julien Boccard, 2008, Journal of chromatography. A.

High-resolution mass spectrometry as an alternative detection method to tandem mass spectrometry for the analysis of endogenous steroids in serum.

S. Rudaz, N. Baume, M. Saugy, 2017, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Longitudinal evaluation of multiple biomarkers for the detection of testosterone gel administration in women with normal menstrual cycle.

S. Rudaz, M. Saugy, J. Boccard, 2021, Drug testing and analysis.

Harnessing the complexity of metabolomic data with chemometrics

Serge Rudaz, Julien Boccard, S. Rudaz, 2014 .

Multivariate data analysis of rapid LC-TOF/MS experiments from Arabidopsis thaliana stressed by wounding

Serge Rudaz, Julien Boccard, Jean-Luc Wolfender, 2007 .

Quantitative monitoring of tamoxifen in human plasma extended to 40 metabolites using liquid-chromatography high-resolution mass spectrometry: new investigation capabilities for clinical pharmacology

S. Rudaz, B. Testa, K. Zaman, 2014, Analytical and Bioanalytical Chemistry.

Development of a two-step screening ESI-TOF-MS method for rapid determination of significant stress-induced metabolome modifications in plant leaf extracts: the wound response in Arabidopsis thaliana as a case study.

Serge Rudaz, Julien Boccard, Jean-Luc Wolfender, 2007, Journal of separation science.

Metabolomics reveals herbivore-induced metabolites of resistance and susceptibility in maize leaves and roots.

S. Rudaz, M. Erb, G. Glauser, 2013, Plant, cell & environment.

Analysis of Metabolomics Data—A Chemometrics Perspective

Serge Rudaz, Julien Boccard, S. Rudaz, 2020 .

Toward a better understanding of chronic kidney disease with complementary chromatographic methods hyphenated with mass spectrometry for improved polar metabolome coverage.

Serge Rudaz, Julien Boccard, Pierre Lescuyer, 2019, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Extracting Knowledge from MS Clinical Metabolomic Data: Processing and Analysis Strategies.

Serge Rudaz, Julien Boccard, S. Rudaz, 2018, Methods in molecular biology.

Mass spectrometry-based metabolomics oriented by correlation analysis for wound-induced molecule discovery: identification of a novel jasmonate glucoside.

Serge Rudaz, Julien Boccard, Jean-Luc Wolfender, 2010, Phytochemical analysis : PCA.

Unravelling the effects of multiple experimental factors in metabolomics, analysis of human neural cells with hydrophilic interaction liquid chromatography hyphenated to high resolution mass spectrometry.

S. Rudaz, L. Stoppini, J. Boccard, 2017, Journal of chromatography. A.

High-throughput identification of monoclonal antibodies after compounding by UV spectroscopy coupled to chemometrics analysis

Serge Rudaz, Julien Boccard, Myriam Taverna, 2016, Analytical and Bioanalytical Chemistry.

Assessing Susceptibility to Epilepsy in Three Rat Strains Using Brain Metabolic Profiling Based on HRMAS NMR Spectroscopy and Chemometrics.

C. Deransart, A. Depaulis, F. Fauvelle, 2015, Journal of proteome research.

Multi-way PLS regression: Monotony convergence of tri-linear PLS2 and optimality of parameters

Serge Rudaz, Mohamed Hanafi, Julien Boccard, 2015, Comput. Stat. Data Anal..

Processing of NMR and MS metabolomics data using chemometrics methods: a global tool for fungi biotransformation reactions monitoring

A. Petit, R. Molinié, D. Mathiron, 2019, Metabolomics.

Integration of Metabolomic Data From Multiple Analytical Platforms: Towards Extensive Coverage of the Metabolome

Serge Rudaz, Julien Boccard, S. Rudaz, 2018 .

Identification of a predictive metabolic signature of response to immune checkpoint inhibitors in non-small cell lung cancer: METABO-ICI clinical study protocol.

C. Aspord, A. Le Gouellec, D. Moro-Sibilot, 2021, Respiratory medicine and research.

Extended steroid profiling in H295R cells provides deeper insight into chemical-induced disturbances of steroidogenesis: Exemplified by prochloraz and anabolic steroids

A. Odermatt, J. Boccard, Víctor González-Ruiz, 2023, Molecular and Cellular Endocrinology.

Ultra-high performance supercritical fluid chromatography coupled with quadrupole-time-of-flight mass spectrometry as a performing tool for bioactive analysis.

Davy Guillarme, Julien Boccard, Jean-Luc Veuthey, 2016, Journal of chromatography. A.

Low-polarity untargeted metabolomic profiling as a tool to gain insight into seminal fluid

J. Boccard, R. Rahban, S. Nef, 2023, Metabolomics.

Gaining Insights Into Metabolic Networks Using Chemometrics and Bioinformatics: Chronic Kidney Disease as a Clinical Model

S. Rudaz, F. Jourdan, M. Hanafi, 2021, Frontiers in Molecular Biosciences.

Straightforward quantification of endogenous steroids with liquid chromatography-tandem mass spectrometry: Comparing calibration approaches.

J. Boccard, R. Nicoli, T. Kuuranne, 2023, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Multitargeted Internal Calibration for the Quantification of Chronic Kidney Disease-Related Endogenous Metabolites Using Liquid Chromatography–Mass Spectrometry

B. Ponte, J. Boccard, D. Jaques, 2023, Analytical chemistry.

DynaStI: A Dynamic Retention Time Database for Steroidomics

Serge Rudaz, Alan Bridge, Víctor González-Ruiz, 2019, Metabolites.

Prediction of retention time in reversed-phase liquid chromatography as a tool for steroid identification.

Giuseppe Marco Randazzo, S. Rudaz, D. Guillarme, 2016, Analytica chimica acta.

Indirect quantitative structure-retention relationship for steroid identification: A chemometric challenge at “Chimiométrie 2016”

Giuseppe Marco Randazzo, E. Vigneau, S. Rudaz, 2017 .

Quantification of glucuronidated and sulfated steroids in human urine by ultra-high pressure liquid chromatography quadrupole time-of-flight mass spectrometry

J. Veuthey, S. Rudaz, M. Saugy, 2011, Analytical and bioanalytical chemistry.

A steroidomic approach for biomarkers discovery in doping control.

J. Veuthey, S. Rudaz, M. Hanafi, 2011, Forensic science international.

IEF pattern classification‐derived criteria for the identification of epoetin‐δ in urine

N. Robinson, M. Saugy, P. Sottas, 2010, Electrophoresis.

Comprehensive plasma steroidomics reveals subtle alterations of systemic steroid profile in patients at different stages of prostate cancer disease

J. Boccard, Elena Tobolkina, Serge Rudaz, 2024, Scientific reports.

Analysis of experimental design with multivariate response: A contribution using multiblock techniques

Serge Rudaz, Mohamed Hanafi, Julien Boccard, 2011 .

Efficiently handling high‐dimensional data from multifactorial designs with unequal group sizes using Rebalanced ASCA (RASCA)

R. Zenobi, J. Boccard, S. Giannoukos, 2022, Journal of Chemometrics.

Mixture effects of pharmaceuticals carbamazepine, diclofenac and venlafaxine on Mytilus galloprovincialis mussel probed by metabolomics and proteogenomics combined approach.

J. Boccard, F. Courant, H. Fenet, 2023, The Science of the total environment.