S. Kishino

发表

Intestinal microbe-dependent ω3 lipid metabolite αKetoA prevents inflammatory diseases in mice and cynomolgus macaques

T. Tomonaga, H. Shimano, T. Matsuzaka, 2022, Mucosal immunology.

Characterization of hydroxy fatty acid dehydrogenase involved in polyunsaturated fatty acid saturation metabolism in Lactobacillus plantarum AKU 1009a

S. Kishino, N. Kitamura, J. Ogawa, 2015 .

Characterization of starch-accumulating duckweeds, Wolffia globosa, as renewable carbon source for bioethanol production

H. Kikukawa, S. Kishino, J. Ogawa, 2016 .

Production of ricinoleic acid-containing monoestolide triacylglycerides in an oleaginous diatom, Chaetoceros gracilis

H. Fukuzawa, Masataka Kajikawa, S. Kishino, 2016, Scientific Reports.

A Gut Microbial Metabolite of Linoleic Acid, 10-Hydroxy-cis-12-octadecenoic Acid, Ameliorates Intestinal Epithelial Barrier Impairment Partially via GPR40-MEK-ERK Pathway*

Takuya Suzuki, M. Arita, S. Kishino, 2014, The Journal of Biological Chemistry.

10-Oxo-trans-11-octadecenoic acid generated from linoleic acid by a gut lactic acid bacterium Lactobacillus plantarum is cytoprotective against oxidative stress.

S. Kishino, N. Kitamura, J. Ogawa, 2016, Toxicology and applied pharmacology.

Inhibitory effect of the gut microbial linoleic acid metabolites, 10-oxo-trans-11-octadecenoic acid and 10-hydroxy-cis-12-octadecenoic acid, on BV-2 microglial cell activation.

A. Akaike, S. Kishino, N. Kitamura, 2018, Journal of pharmacological sciences.

α‐Linolenic acid‐derived metabolites from gut lactic acid bacteria induce differentiation of anti‐inflammatory M2 macrophages through G protein‐coupled receptor 40

T. Kusakabe, F. Tani, T. Kawada, 2018, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Enzyme systems involved in glucosinolate metabolism in Companilactobacillus farciminis KB1089

T. Bamba, S. Kishino, J. Ogawa, 2021, Scientific reports.

Synthesized enone fatty acids resembling metabolites from gut microbiota suppress macrophage-mediated inflammation in adipocytes.

R. Yu, T. Kawada, S. Kishino, 2017, Molecular nutrition & food research.

Gut microbial metabolites of linoleic acid are metabolized by accelerated peroxisomal β-oxidation in mammalian cells.

S. Kishino, N. Kitamura, J. Ogawa, 2019, Biochimica et biophysica acta. Molecular and cell biology of lipids.

Title Characterization of the linoleic acid Δ 9 hydratase catalyzing the first step of polyunsaturated fatty acid saturation metabolism in Lactobacillus plantarum

S. Kishino, J. Ogawa, A. Hirata, 2018 .

10-oxo-12(Z)-octadecenoic acid, a linoleic acid metabolite produced by gut lactic acid bacteria, potently activates PPARγ and stimulates adipogenesis.

R. Yu, T. Kawada, S. Kishino, 2015, Biochemical and biophysical research communications.

Polyunsaturated fatty acid saturation by gut lactic acid bacteria affecting host lipid composition

H. Kiyono, K. Ueda, M. Arita, 2013, Proceedings of the National Academy of Sciences.

Conjugated linoleic acid production from linoleic acid by lactic acid bacteria

S. Kishino, J. Ogawa, S. Shimizu, 2002 .

Gut microbial fatty acid metabolites (KetoA and KetoC) affect the progression of nonalcoholic steatohepatitis and reverse cholesterol transport metabolism in mouse model.

S. Kishino, J. Ogawa, Yuta Yamamoto, 2020, Lipids.

Immunomodulatory activity of a gut microbial metabolite of dietary linoleic acid, 10-hydroxy-cis-12-octadecenoic acid, associated with improved antioxidant/detoxifying defences

S. Kishino, J. Ogawa, E. Cocca, 2014 .

Lipid production through simultaneous utilization of glucose, xylose, and l-arabinose by Pseudozyma hubeiensis: a comparative screening study

S. Kishino, J. Ogawa, M. Ohkuma, 2016, AMB Express.

Novel multi-component enzyme machinery in lactic acid bacteria catalyzing C=C double bond migration useful for conjugated fatty acid synthesis.

S. Kishino, J. Ogawa, S. Shimizu, 2011, Biochemical and biophysical research communications.

Gut Microbial Fatty Acid Metabolites Reduce Triacylglycerol Levels in Hepatocytes

T. Kawada, S. Kishino, N. Kitamura, 2015, Lipids.

Evaluation of electron-transferring cofactor mediating enzyme systems involved in urolithin dehydroxylation in Gordonibacter urolithinfaciens DSM 27213.

S. Kishino, J. Ogawa, Hiroaki Yamamoto, 2020, Journal of bioscience and bioengineering.

Medium-chain triglycerides inhibit long-chain triglyceride-induced GIP secretion through GPR120-dependent inhibition of CCK

S. Kishino, J. Ogawa, A. Hirasawa, 2021, iScience.

Structural differences in bacterial lipopolysaccharides determine atherosclerotic plaque progression by regulating the accumulation of neutrophils.

K. Hirata, S. Kishino, N. Kitamura, 2022, Atherosclerosis.

Production of GABA-enriched tomato juice by Lactiplantibacillus plantarum KB1253.

S. Kishino, J. Ogawa, Tetsuya Fukaya, 2022, Journal of bioscience and bioengineering.

Dietary-protein sources modulate host susceptibility to Clostridioides difficile infection through the gut microbiota.

Aina Gotoh, K. Okano, A. Hirayama, 2022, Cell reports.

Lactic acid bacteria–derived γ-linolenic acid metabolites are PPARδ ligands that reduce lipid accumulation in human intestinal organoids

H. Kiyono, Shintaro Sato, K. Nagata, 2022, The Journal of biological chemistry.

Biohydrogenation of C20 polyunsaturated fatty acids by anaerobic bacteria[S]

S. Kishino, J. Ogawa, S. Shimizu, 2014, Journal of Lipid Research.

The anti‐inflammatory effect of 10‐oxo‐trans‐11‐octadecenoic acid (KetoC) on RAW 264.7 cells stimulated with Porphyromonas gingivalis lipopolysaccharide

S. Kishino, J. Ogawa, K. Yamazaki, 2018, Journal of periodontal research.

Direct ethanol production from starch using a natural isolate, Scheffersomyces shehatae: Toward consolidated bioprocessing

S. Kishino, J. Ogawa, Minako Kikukawa, 2015, Scientific Reports.

Lipid production via simultaneous conversion of glucose and xylose by a novel yeast, Cystobasidium iriomotense

S. Kishino, J. Ogawa, M. Ohkuma, 2018, PloS one.

β-Glucuronidase from Lactobacillus brevis useful for baicalin hydrolysis belongs to glycoside hydrolase family 30

Y. Yonejima, S. Kishino, J. Ogawa, 2014, Applied Microbiology and Biotechnology.

Metabolic diversity in biohydrogenation of polyunsaturated fatty acids by lactic acid bacteria involving conjugated fatty acid production

S. Kishino, J. Ogawa, S. Shimizu, 2009, Applied Microbiology and Biotechnology.

Hydroxy fatty acid production by Pediococcus sp.

S. Kishino, J. Ogawa, S. Shimizu, 2013 .

A bacterial metabolite induces Nrf2-mediated anti-oxidative responses in gingival epithelial cells by activating the MAPK signaling pathway.

S. Kishino, J. Ogawa, K. Tabeta, 2019, Archives of oral biology.

Conjugated α-linolenic acid production from α-linolenic acid by Lactobacillus plantarum AKU 1009a

S. Kishino, J. Ogawa, S. Shimizu, 2003 .

Rational Engineering of Hydratase from Lactobacillus acidophilus Reveals Critical Residues Directing Substrate Specificity and Regioselectivity

B. Eser, S. Kishino, J. Ogawa, 2019, Chembiochem : a European journal of chemical biology.

Conjugated Linoleic Acid Accumulation via 10-Hydroxy-12-Octadecaenoic Acid during Microaerobic Transformation of Linoleic Acid by Lactobacillus acidophilus

S. Kishino, J. Ogawa, S. Shimizu, 2001, Applied and Environmental Microbiology.

A possible beneficial effect of Bacteroides on faecal lipopolysaccharide activity and cardiovascular diseases

Takuji Yamada, K. Hirata, A. Kondo, 2020, Scientific Reports.

Production of conjugated fatty acids by lactic acid bacteria.

S. Kishino, J. Ogawa, S. Shimizu, 2005, Journal of bioscience and bioengineering.

Novel alcohol oxidase with glycolate oxidase activity from Ochrobactrum sp. AIU 033

S. Kishino, J. Ogawa, M. Kataoka, 2014 .

Recent trends in the field of lipid engineering.

H. Kikukawa, S. Kishino, E. Sakuradani, 2022, Journal of bioscience and bioengineering.

Application of Enzymatic Reactions Involving Electron Transfer and Energy Supply for the Production of Useful Chemicals

S. Kishino, J. Ogawa, M. Hibi, 2020 .

Screening and Industrial Application of Unique Microbial Reactions Involved in Nucleic Acid and Lipid Metabolisms

S. Kishino, J. Ogawa, S. Shimizu, 2006, Bioscience, biotechnology, and biochemistry.

Characterization of the linoleic acid Δ9 hydratase catalyzing the first step of polyunsaturated fatty acid saturation metabolism in Lactobacillus plantarum AKU 1009a.

S. Kishino, N. Kitamura, J. Ogawa, 2015, Journal of bioscience and bioengineering.

Selective production of cis‐9,trans‐11 isomer of conjugated linoleic acid from trans‐vaccenic acid methyl ester by Delacroixia coronata

S. Kishino, J. Ogawa, E. Sakuradani, 2009, Journal of applied microbiology.

Structural Analysis of Conjugated Linoleic Acid Produced by Lactobacillus plantarum, and Factors Affecting Isomer Production

T. Iwashita, S. Kishino, J. Ogawa, 2003, Bioscience, biotechnology, and biochemistry.

Metabolic engineering of oleaginous fungus Mortierella alpina for high production of oleic and linoleic acids.

T. Bamba, H. Kikukawa, S. Kishino, 2017, Bioresource technology.

Characterization of a trifunctional fatty acid desaturase from oleaginous filamentous fungus Mortierella alpina 1S-4 using a yeast expression system.

M. Ochiai, H. Kikukawa, S. Kishino, 2013, Journal of bioscience and bioengineering.

Microbial Production of Functional Polyunsaturated Fatty Acids and Their Derivatives

S. Kishino, J. Ogawa, E. Sakuradani, 2014 .

Polyunsaturated fatty acids production and transformation by Mortierella alpina and anaerobic bacteria

S. Kishino, J. Ogawa, E. Sakuradani, 2012 .

Oils, Microbial Production

S. Kishino, J. Ogawa, E. Sakuradani, 2002 .

The anti-inflammatory effect of the gut lactic acid bacteria-generated metabolite 10-oxo-cis-6,trans-11-octadecadienoic acid on monocytes.

S. Kishino, J. Ogawa, C. Nishiyama, 2020, Biochemical and biophysical research communications.

17(S),18(R)‐epoxyeicosatetraenoic acid generated by cytochrome P450 BM‐3 from Bacillus megaterium inhibits the development of contact hypersensitivity via G‐protein‐coupled receptor 40‐mediated neutrophil suppression

T. Nagatake, S. Kishino, Prabha Tiwari, 2019, FASEB bioAdvances.

A bacterial metabolite ameliorates periodontal pathogen-induced gingival epithelial barrier disruption via GPR40 signaling

T. Ushiki, Y. Mikami, M. Arita, 2018, Scientific Reports.

Conjugated linoleic acid production from castor oil by Lactobacillus plantarum JCM 1551

S. Kishino, J. Ogawa, S. Shimizu, 2004 .

Novel Mechanism of Fatty Acid Sensing in Enteroendocrine Cells: Specific Structures in Oxo‐Fatty Acids Produced by Gut Bacteria Are Responsible for CCK Secretion in STC‐1 Cells via GPR40

H. Hara, S. Kishino, J. Ogawa, 2018, Molecular nutrition & food research.

Dietary cis-9, trans-11-conjugated linoleic acid reduces amyloid β-protein accumulation and upregulates anti-inflammatory cytokines in an Alzheimer’s disease mouse model

Y. Sano, K. Zou, Toshiharu Suzuki, 2021, Scientific Reports.

Fatty Acid Desaturation and Elongation Reactions of Trichoderma sp. 1-OH-2-3

N. Shirasaka, S. Kishino, J. Ogawa, 2009 .

Antimicrobial function of the polyunsaturated fatty acid ketoC in an experimental model of periodontitis.

S. Kishino, J. Ogawa, K. Tabeta, 2019, Journal of periodontology.

Characterization of a new enzyme oxidizing ω-amino group of aminocarboxyric acid, aminoalcohols and amines from Phialemonium sp. AIU 274

Tomoko Sasaki, S. Kishino, J. Ogawa, 2013 .

10‐oxo‐12(Z)‐octadecenoic acid, a linoleic acid metabolite produced by gut lactic acid bacteria, enhances energy metabolism by activation of TRPV1

M. Tominaga, R. Yu, T. Kawada, 2017, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Structure and reaction mechanism of a novel enone reductase

M. Tanokura, S. Kishino, N. Kitamura, 2015, The FEBS journal.

Gut microbiota confers host resistance to obesity by metabolizing dietary polyunsaturated fatty acids

D. Drucker, H. Itoh, M. Arita, 2019, Nature Communications.

Linoleic Acid Isomerase in Lactobacillus plantarum AKU1009a Proved to Be a Multi-Component Enzyme System Requiring Oxidoreduction Cofactors

S. Kishino, J. Ogawa, S. Shimizu, 2011, Bioscience, biotechnology, and biochemistry.

Characterization of a novel l-amino acid oxidase with protein oxidizing activity from Penicillium steckii AIU 027.

S. Kishino, J. Ogawa, Miwa Yamada, 2014, Journal of bioscience and bioengineering.

Ricinoleic Acid and Castor Oil as Substrates for Conjugated Linoleic Acid Production by Washed Cells of Lactobacillus plantarum

S. Kishino, J. Ogawa, S. Shimizu, 2002, Bioscience, biotechnology, and biochemistry.

Microbial production of conjugated fatty acids

S. Kishino, J. Ogawa, S. Shimizu, 2009 .

Title A novel unsaturated fatty acid hydratase toward C(16) to C(22) fatty acids from Lactobacillus acidophilus

Ogawa, S. Kishino, N. Kitamura, 2020 .

A novel unsaturated fatty acid hydratase toward C16 to C22 fatty acids from Lactobacillus acidophilus

S. Kishino, N. Kitamura, J. Ogawa, 2015, Journal of Lipid Research.

CLA production from ricinoleic acid by lactic acid bacteria

S. Kishino, J. Ogawa, S. Shimizu, 2003 .

Effects of the engineering of a single binding pocket residue on specificity and regioselectivity of hydratases from Lactobacillus Acidophilus

B. Eser, S. Kishino, J. Ogawa, 2021, Biochemical Engineering Journal.

Efficient enzymatic production of hydroxy fatty acids by linoleic acid Δ9 hydratase from Lactobacillus plantarum AKU 1009a

S. Kishino, N. Kitamura, A. Saika, 2016, Journal of applied microbiology.

Microbial production of conjugated γ‐linolenic acid from γ‐linolenic acid by Lactobacillus plantarum AKU 1009a

S. Kishino, J. Ogawa, K. Yokozeki, 2010, Journal of applied microbiology.

Production of dicarboxylic acids from novel unsaturated fatty acids by laccase-catalyzed oxidative cleavage

S. Kishino, N. Kitamura, A. Saika, 2016, Bioscience, biotechnology, and biochemistry.

Supplemental feeding of a gut microbial metabolite of linoleic acid, 10-hydroxy-cis-12-octadecenoic acid, alleviates spontaneous atopic dermatitis and modulates intestinal microbiota in NC/nga mice

Takuya Suzuki, Y. Yonejima, S. Kishino, 2017, International journal of food sciences and nutrition.

Characterization of regioselective glycosyltransferase of Rhizobium pusense JCM 16209T useful for resveratrol 4'-O-α-d-glucoside production.

S. Kishino, N. Kitamura, J. Ogawa, 2022, Journal of bioscience and bioengineering.

Estimation of Catechins Concentration of Green Tea Using Hyperspectral Remote Sensing

C. Ryu, M. Suguri, S. Kishino, 2010 .

The relationship between unique gut microbiome-derived lipid metabolites and subsequent revascularization in patients who underwent percutaneous coronary intervention.

S. Kishino, H. Otake, H. Kawamori, 2023, Atherosclerosis.

Estimating the catechin concentrations of new shoots in green tea fields using ground-based hyperspectral imagery.

Ye-Seong Kang, C. Ryu, M. Suguri, 2021, Food chemistry.

A bacterial metabolite ameliorates periodontal pathogen-induced gingival epithelial barrier disruption via GPR40 signaling

T. Ushiki, Y. Mikami, M. Arita, 2018, Scientific Reports.

Hydratase, Dehydrogenase, Isomerase, and Enone Reductase Involved in Fatty Acid Saturation Metabolism

S. Kishino, J. Ogawa, M. Takeuchi, 2018 .

Lipid production through simultaneous utilization of glucose, xylose, and l-arabinose by Pseudozyma hubeiensis: a comparative screening study

S. Kishino, J. Ogawa, M. Ohkuma, 2016, AMB Express.

α‐Linolenic acid‐derived metabolites from gut lactic acid bacteria induce differentiation of anti‐inflammatory M2 macrophages through G protein‐coupled receptor 40

T. Kusakabe, F. Tani, T. Kawada, 2018, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Discovery of an isoflavone oxidative catabolic pathway in legume root microbiota

K. Shirasu, S. Kishino, J. Ogawa, 2023, bioRxiv.

A new aldehyde oxidase catalyzing the conversion of glycolaldehyde to glycolate from Burkholderia sp. AIU 129.

S. Kishino, J. Ogawa, M. Kataoka, 2015, Journal of bioscience and bioengineering.

A gut microbial metabolite of linoleic acid ameliorates liver fibrosis by inhibiting TGF-β signaling in hepatic stellate cells

S. Kishino, T. Hosooka, Yusei Hosokawa, 2023, Scientific reports.

BIOTECHNOLOGICALLY RELEVANT ENZYMES AND PROTEINS β-Glucuronidase from Lactobacillus brevis useful for baicalin hydrolysis belongs to glycoside hydrolase family 30

Y. Yonejima, S. Kishino, J. Ogawa, 2014 .

Metabolic diversity in biohydrogenation of polyunsaturated fatty acids by lactic acid bacteria involving conjugated fatty acid production

S. Kishino, J. Ogawa, S. Shimizu, 2009, Applied Microbiology and Biotechnology.

Microbial production of conjugated γ‐linolenic acid from γ‐linolenic acid by Lactobacillus plantarum AKU 1009a

S. Kishino, J. Ogawa, S. Shimizu, 2010, Journal of Applied Microbiology.

A search for microorganisms producing medium-chain alkanes from aldehydes.

S. Kishino, J. Ogawa, M. Muramatsu, 2018, Journal of bioscience and bioengineering.

Characterization of a trifunctional fatty acid desaturase from oleaginous filamentous fungus Mortierella alpina 1S-4 using a yeast expression system.

M. Ochiai, H. Kikukawa, S. Kishino, 2013, Journal of bioscience and bioengineering.

The gut lactic acid bacteria metabolite, 10-oxo-cis-6,trans-11-octadecadienoic acid, suppresses inflammatory bowel disease in mice by modulating the NRF2 pathway and GPCR-signaling

Masakazu Hachisu, S. Kishino, J. Ogawa, 2024, bioRxiv.

Characterization of hydroxy fatty acid dehydrogenase involved in polyunsaturated fatty acid saturation metabolism in plantarum

S. Kishino, N. Kitamura, M. Takeuchi, 2019 .