Shan Lu

发表

Neutralizing Epitopes in the Membrane-Proximal External Region of HIV-1 gp41 Are Influenced by the Transmembrane Domain and the Plasma Membrane

Jamie K. Scott, Jason E. Donald, D. Burton, 2012, Journal of Virology.

DNA vaccines expressing glycoprotein complex II antigens gM and gN elicited neutralizing antibodies against multiple human cytomegalovirus (HCMV) isolates.

W. Britt, Shixia Wang, Shan Lu, 2007, Vaccine.

Measurement of neutralizing antibody responses against H5N1 clades in immunized mice and ferrets using pseudotypes expressing influenza hemagglutinin and neuraminidase

Boping Zhou, V. Deubel, P. Buchy, 2009, Vaccine.

Structural Analysis of the Glycosylated Intact HIV-1 gp120–b12 Antibody Complex Using Hydroxyl Radical Protein Footprinting

Oliver C. Grant, R. Woods, Keigo Ito, 2017, Biochemistry.

Small-Molecule Targeting of Proliferating Cell Nuclear Antigen Chromatin Association Inhibits Tumor Cell Growth

L. Malkas, Shan Lu, Zongqing Tan, 2012, Molecular Pharmacology.

Relative contributions of codon usage, promoter efficiency and leader sequence to the antigen expression and immunogenicity of HIV-1 Env DNA vaccine.

F. He, Shixia Wang, Shan Lu, 2006, Vaccine.

Assays for the assessment of neutralizing antibody activities against Severe Acute Respiratory Syndrome (SARS) associated coronavirus (SCV)

Shixia Wang, Shan Lu, Te-Hui Chou, 2005, Journal of Immunological Methods.

Two-Way Antigenic Cross-Reactivity between Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) and Group 1 Animal CoVs Is Mediated through an Antigenic Site in the N-Terminal Region of the SARS-CoV Nucleoprotein

A. Vlasova, L. Saif, Shan Lu, 2007, Journal of Virology.

Profiles of acute cytokine and antibody responses in patients infected with avian influenza A H 7 N 9 Authors

Yong Liu, Rui Huang, Chao Wu, 2017 .

A Novel DDB2-ATM Feedback Loop Regulates Human Cytomegalovirus Replication

A. Brass, T. Kowalik, Shixia Wang, 2013, Journal of Virology.

Enhanced Immunogenicity of gp120 Protein When Combined with Recombinant DNA Priming To Generate Antibodies That Neutralize the JR-FL Primary Isolate of Human Immunodeficiency Virus Type 1

D. Montefiori, J. Arthos, Shixia Wang, 2005, Journal of Virology.

Human Immunodeficiency Virus Type 1 Neutralize the JR-FL Primary Isolate of Priming To Generate Antibodies That When Combined with Recombinant DNA Enhanced Immunogenicity of gp 120 Protein

D. Montefiori, J. Arthos, Shixia Wang, 2005 .

Enhanced Immunogenicity of gp120 Protein When Combined with Recombinant DNA Priming To Generate Antibodies That Neutralize the JR-FL Primary Isolate of Human Immunodeficiency Virus Type 1

D. Montefiori, J. Arthos, Shixia Wang, 2005, Journal of Virology.

DNA immunization as a technology platform for monoclonal antibody induction

Shixia Wang, Shan Lu, Shuying Liu, 2016, Emerging Microbes & Infections.

Characterization of H9N2 influenza viruses isolated from vaccinated flocks in an integrated broiler chicken operation in eastern China during a 5 year period (1998-2002).

Wenbo Liu, Shan Lu, Xiufan Liu, 2008, The Journal of general virology.

Influenza H5 Hemagglutinin DNA Primes the Antibody Response Elicited by the Live Attenuated Influenza A/Vietnam/1203/2004 Vaccine in Ferrets

Shixia Wang, Shan Lu, H. Jin, 2011, PloS one.

A Novel Immunodiagnostic Assay to Detect Serum Antibody Response against Selected Soluble Egg Antigen Fractions from Schistosoma japonicum

Shixia Wang, Shan Lu, Xiaoting Wang, 2012, PloS one.

Current progress of DNA vaccine studies in humans

Shixia Wang, Shan Lu, Jill M. Grimes-Serrano, 2008, Expert review of vaccines.

Immunogenicity and protection efficacy of subunit-based smallpox vaccines using variola major antigens.

Shixia Wang, Shan Lu, Te-Hui Chou, 2008, Virology.

Immunogenicity and protection efficacy of monovalent and polyvalent poxvirus vaccines that include the D8 antigen

Shixia Wang, Shan Lu, Te-Hui Chou, 2006, Virology.

Use of ELISpot assay to study HBs-specific B cell responses in vaccinated and HBV infected humans

J. Xia, Yong Liu, Yuxin Chen, 2018, Emerging Microbes & Infections.

Involvement of CD8+ T cell-mediated immune responses in LcrV DNA vaccine induced protection against lethal Yersinia pestis challenge.

Shixia Wang, Shan Lu, J. Goguen, 2011, Vaccine.

Delivery of DNA to skin by particle bombardment.

Shixia Wang, Shan Lu, Swati Joshi, 2004, Methods in molecular biology.

Structural analysis of a novel rabbit monoclonal antibody R53 targeting an epitope in HIV-1 gp120 C4 region critical for receptor and co-receptor binding

X. Kong, Shixia Wang, Shan Lu, 2015, Emerging Microbes & Infections.

Heterologous HA DNA vaccine prime--inactivated influenza vaccine boost is more effective than using DNA or inactivated vaccine alone in eliciting antibody responses against H1 or H3 serotype influenza viruses.

A. García-Sastre, Shixia Wang, Shan Lu, 2008, Vaccine.

Polyvalent HIV-1 Env vaccine formulations delivered by the DNA priming plus protein boosting approach are effective in generating neutralizing antibodies against primary human immunodeficiency virus type 1 isolates from subtypes A, B, C, D and E.

J. Mascola, Shixia Wang, Shan Lu, 2006, Virology.

Improved induction of antibodies against key neutralizing epitopes by HIV-1 gp120 DNA prime-protein boost vaccination compared to gp120 protein only vaccination

J. Binley, D. Montefiori, Shixia Wang, 2021 .

Pilot study on the immunogenicity of paired Env immunogens from mother-to-child transmitted HIV-1 isolates

Shengqing Wan, Shixia Wang, Shan Lu, 2012, Human vaccines & immunotherapeutics.

A versatile vector for the production of pseudotyped viruses expressing gp120 antigens from different clades of primary HIV-1 isolates.

Shixia Wang, Shan Lu, Jing-yun Li, 2011, Journal of virological methods.

Antibody responses elicited through homologous or heterologous prime-boost DNA and protein vaccinations differ in functional activity and avidity.

J. Arthos, Shixia Wang, Shan Lu, 2010, Vaccine.

Improved Induction of Antibodies against Key Neutralizing Epitopes by Human Immunodeficiency Virus Type 1 gp120 DNA Prime-Protein Boost Vaccination Compared to gp120 Protein-Only Vaccination

J. Binley, D. Montefiori, Shixia Wang, 2008, Journal of Virology.

Cross-subtype antibody and cellular immune responses induced by a polyvalent DNA prime-protein boost HIV-1 vaccine in healthy human volunteers.

S. Green, A. Rothman, F. Ennis, 2008, Vaccine.

Focusing the immune response on the V3 loop, a neutralizing epitope of the HIV-1 gp120 envelope.

S. Zolla-Pazner, Shixia Wang, Shan Lu, 2008, Virology.

Antigen-specific H1N1 influenza antibody responses in acute respiratory tract infections and their relation to influenza infection and disease course.

D. Hoaglin, Shan Lu, E. Boyer, 2014, Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology.

Cytokine markers as predictors of type of respiratory infection in patients during the influenza season.

Shan Lu, J. Haran, R. Buglione-Corbett, 2013, The American journal of emergency medicine.

C-reactive protein as predictor of bacterial infection among patients with an influenza-like illness.

S. Suner, Shan Lu, J. Haran, 2013, The American journal of emergency medicine.

Identification of T Cell Epitopes in the Spike Glycoprotein of Severe Acute Respiratory Syndrome Coronavirus 2 in Rhesus Macaques

Zhengrong Hu, Shan Lu, Zhanlong He, 2021, The Journal of Immunology.

Dynamic changes of cytotoxic T lymphocytes (CTLs), natural killer (NK) cells, and natural killer T (NKT) cells in patients with acute hepatitis B infection

Shixia Wang, Shan Lu, Yaping Han, 2011, Virology Journal.

Differential induction of anti-V3 crown antibodies with cradle- and ladle-binding modes in response to HIV-1 envelope vaccination.

N. Haigwood, S. Zolla-Pazner, M. Gorny, 2017, Vaccine.

Serological reports of human infections of H7 and H9 avian influenza viruses in northern China.

S. D. de Vlas, W. Cao, J. Richardus, 2009, Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology.

Follicular regulatory T cells repress cytokine production by follicular helper T cells and optimize IgG responses in mice

Hong Liu, A. Dent, Shixia Wang, 2016, European journal of immunology.

Polyvalent AIDS vaccines.

Shixia Wang, Shan Lu, Jill M. Grimes Serrano, 2010, Current HIV research.

A cGAS-Independent STING/IRF7 Pathway Mediates the Immunogenicity of DNA Vaccines

Shixia Wang, Shan Lu, K. Fitzgerald, 2016, The Journal of Immunology.

Identification of Aim2 as a Sensor for DNA Vaccines

Shixia Wang, Shan Lu, K. Fitzgerald, 2015, The Journal of Immunology.

DNA Vaccines for Biodefense and Emerging and Neglected Infectious Diseases

Shixia Wang, Shan Lu, Jill M. Grimes-Serrano, 2009, Vaccines for Biodefense and Emerging and Neglected Diseases.

Relative immunogenicity and protection potential of candidate Yersinia Pestis antigens against lethal mucosal plague challenge in Balb/C mice

Shixia Wang, Shan Lu, J. Goguen, 2008, Vaccine.

Passive immunotherapy of Bacillus anthracis pulmonary infection in mice with antisera produced by DNA immunization.

J. Shiloach, Shixia Wang, Shan Lu, 2006, Vaccine.

Identification of Two Neutralizing Regions on the Severe Acute Respiratory Syndrome Coronavirus Spike Glycoprotein Produced from the Mammalian Expression System

Shixia Wang, Shan Lu, H. Cao, 2005, Journal of Virology.

Optimal designs of an HA-based DNA vaccine against H7 subtype influenza viruses

Wuchun Cao, Shixia Wang, Shan Lu, 2014, Human vaccines & immunotherapeutics.

Editorial overview: vaccines against challenging viral pathogens and new vaccine technology.

Shan Lu, 2014, Current opinion in virology.

Epitope mapping and biological function analysis of antibodies produced by immunization of mice with an inactivated Chinese isolate of severe acute respiratory syndrome-associated coronavirus (SARS-CoV)

Shixia Wang, Shan Lu, Qingyu Zhu, 2005, Virology.

Potent monoclonal antibodies against Clostridium difficile toxin A elicited by DNA immunization

Shixia Wang, Shan Lu, Yanling Xiao, 2013, Human vaccines & immunotherapeutics.

DNA vaccine prime followed by boost with live attenuated virus significantly improves antigen-specific T cell responses against human cytomegalovirus

Shixia Wang, Shan Lu, Siyuan Shen, 2013, Human vaccines & immunotherapeutics.

Protective antibody responses against Clostridium difficile elicited by a DNA vaccine expressing the enzymatic domain of toxin B

Shixia Wang, Shan Lu, Yanling Xiao, 2013, Human vaccines & immunotherapeutics.

A Novel Genotype H9N2 Influenza Virus Possessing Human H5N1 Internal Genomes Has Been Circulating in Poultry in Eastern China since 1998

Wenbo Liu, Song Gao, Shan Lu, 2009, Journal of Virology.

Vaccinology: Precisely tuned antibodies nab HIV

Shan Lu, P. Clapham, 2011, Nature.

Novel DNA vaccine based on hepatitis B virus core gene induces specific immune responses in Balb/c mice.

Shixia Wang, Shan Lu, Zu-hu Huang, 2005, World journal of gastroenterology.

Combination DNA plus protein HIV vaccines

Shan Lu, 2006, Springer Seminars in Immunopathology.

The safety and tolerability of an HIV-1 DNA prime-protein boost vaccine (DP6-001) in healthy adult volunteers.

S. Green, A. Rothman, Shixia Wang, 2008, Vaccine.

Multifunctional T-Cell Characteristics Induced by a Polyvalent DNA Prime/Protein Boost Human Immunodeficiency Virus Type 1 Vaccine Regimen Given to Healthy Adults Are Dependent on the Route and Dose of Administration

P. Goepfert, Shixia Wang, Shan Lu, 2008, Journal of Virology.

RNA Interference-Mediated Targeting of Human Cytomegalovirus Immediate-Early or Early Gene Products Inhibits Viral Replication with Differential Effects on Cellular Functions

M. Debatis, T. Kowalik, Shixia Wang, 2012, Journal of Virology.

Intracellular accumulation of a 46 kDa species of mouse prion protein as a result of loss of glycosylation in cultured mammalian cells.

J. Langeveld, Shan Lu, D. Tipper, 2006, Biochemical and biophysical research communications.

Cross reactivity of serum antibody responses elicited by DNA vaccines expressing HA antigens from H1N1 subtype influenza vaccines in the past 30 years

Shixia Wang, Shan Lu, Huaiqing Chen, 2013, Human vaccines & immunotherapeutics.

Technical transformation of biodefense vaccines.

Shixia Wang, Shan Lu, 2009, Vaccine.

A DNA vaccine producing LcrV antigen in oligomers is effective in protecting mice from lethal mucosal challenge of plague

Shixia Wang, Shan Lu, J. Goguen, 2004, Vaccine.

An E2F1-Mediated DNA Damage Response Contributes to the Replication of Human Cytomegalovirus

M. Pickering, M. Debatis, T. Kowalik, 2011, PLoS pathogens.

Removing N-Terminal Sequences in Pre-S1 Domain Enhanced Antibody and B-Cell Responses by an HBV Large Surface Antigen DNA Vaccine

Shixia Wang, Shan Lu, Guohong Ge, 2012, PloS one.

HIV-1 R5 Macrophage-Tropic Envelope Glycoprotein Trimers Bind CD4 with High Affinity, while the CD4 Binding Site on Non-macrophage-tropic, T-Tropic R5 Envelopes Is Occluded

J. Luban, Shixia Wang, Shan Lu, 2017, Journal of Virology.

Association of serum gamma-glutamyl transferase with treatment outcome in chronic hepatitis B patients.

Xiaomin Yan, J. Xia, Yong Liu, 2015, World journal of gastroenterology.

Using DNA Immunization to Elicit Monoclonal Antibodies in Mice, Rabbits, and Humans.

Shixia Wang, Shan Lu, Shuying Liu, 2018, Human gene therapy.

Synergistic enhancement of immunogenicity and protection in mice against Schistosoma japonicum with codon optimization and electroporation delivery of SjTPI DNA vaccines.

Shixia Wang, Shan Lu, Xiaoting Wang, 2010, Vaccine.

One Group's Historical Reflections on DNA Vaccine Development

Shan Lu, H. Robinson, E. Fynan, 2018, Human gene therapy.

Increased immunogenicity of human immunodeficiency virus gp120 engineered to express Galalpha1-3Galbeta1-4GlcNAc-R epitopes.

Shixia Wang, Shan Lu, U. Galili, 2006, Journal of virology.

Evaluation of the Role of LcrV-Toll-Like Receptor 2-Mediated Immunomodulation in the Virulence of Yersinia pestis

Shixia Wang, Shan Lu, E. Lien, 2007, Infection and Immunity.

Immunogenicity of DNA vaccines in humans: It takes two to tango

Shan Lu, 2008, Human vaccines.

Human versus HIV: round 2 defeat in AIDS vaccine development

Shan Lu, 2008, Expert review of vaccines.

Polyvalent DNA prime and envelope protein boost HIV‐1 vaccine elicits humoral and cellular responses and controls plasma viremia in rhesus macaques following rectal challenge with an R5 SHIV isolate

J. Mascola, D. Montefiori, Shixia Wang, 2005, Journal of medical primatology.

Independent but not synergistic enhancement to the immunogenicity of DNA vaccine expressing HIV-1 gp120 glycoprotein by codon optimization and C3d fusion in a mouse model.

Shixia Wang, Shan Lu, Siyuan Shen, 2004, Vaccine.

Increased sensitivity for detecting avian influenza-specific antibodies by a modified hemagglutination inhibition assay using horse erythrocytes.

W. Cao, Shixia Wang, Shan Lu, 2008, Journal of virological methods.

Definitive toxicology and biodistribution study of a polyvalent DNA prime/protein boost human immunodeficiency virus type 1 (HIV-1) vaccine in rabbits.

Shixia Wang, Shan Lu, R. Pal, 2006, Vaccine.

Antigen engineering can play a critical role in the protective immunity elicited by Yersinia pestis DNA vaccines.

Shixia Wang, Shan Lu, J. Goguen, 2010, Vaccine.

Expression and immunogenicity of novel subunit enterovirus 71 VP1 antigens.

Weihua Gan, Shixia Wang, Shan Lu, 2012, Biochemical and biophysical research communications.

Cross-clade neutralizing antibodies against HIV-1 induced in rabbits by focusing the immune response on a neutralizing epitope.

S. Zolla-Pazner, T. Wrin, Shixia Wang, 2009, Virology.

Screening of primary gp120 immunogens to formulate the next generation polyvalent DNA prime-protein boost HIV-1 vaccines

D. Montefiori, J. Arthos, Shixia Wang, 2017, Human vaccines & immunotherapeutics.

Serum Cytokine Profiles Associated with Specific Adjuvants Used in a DNA Prime-Protein Boost Vaccination Strategy

Shixia Wang, Shan Lu, E. Lien, 2013, PloS one.

Repurposing non-antifungal drugs auranofin and pentamidine in combination as fungistatic antifungal agents against C. albicans

Shan Lu, Yijing Liang, Peiyan Yuan, 2022, Frontiers in Cellular and Infection Microbiology.

The wide utility of rabbits as models of human diseases

L. BenMohamed, G. Kaplan, G. McFadden, 2018, Experimental & Molecular Medicine.

Immunization of the Female Genital Tract with a DNA-Based Vaccine

H. Robinson, Shan Lu, Deborah J Anderson, 1998, Infection and Immunity.

Profiles of B and T cell immune responses elicited by different forms of the hepatitis B virus surface antigen.

Shixia Wang, Shan Lu, Guohong Ge, 2010, Vaccine.

Application of the polyvalent approach to HIV-1 vaccine development.

Shixia Wang, Shan Lu, J. Hurwitz, 2005, Current drug targets. Infectious disorders.

N-Linked Glycosylation at an Appropriate Position in the Pre-S2 Domain Is Critical for Cellular and Humoral Immunity against Middle HBV Surface Antigen.

Shixia Wang, Shan Lu, Zu-hu Huang, 2015, The Tohoku journal of experimental medicine.

EV71 vaccines: a milestone in the history of global vaccine development

Shan Lu, 2014, Emerging Microbes & Infections.

EV71: an emerging infectious disease vaccine target in the Far East?

Shixia Wang, Shan Lu, Y. Qian, 2010, Vaccine.

DNA Immunization for HIV Vaccine Development

Shixia Wang, Shan Lu, Yuxing Chen, 2014, Vaccines.

Levels of N-linked glycosylation on the V1 loop of HIV-1 Env proteins and their relationship to the antigenicity of Env from primary viral isolates.

Shixia Wang, Shan Lu, Siyuan Shen, 2008, Current HIV research.

The ability of Hepatitis B surface antigen DNA vaccine to elicit cell-mediated immune responses, but not antibody responses, was affected by the deglysosylation of S antigen.

Yan Lin, Shixia Wang, Shan Lu, 2008, Vaccine.

The relative immunogenicity of DNA vaccines delivered by the intramuscular needle injection, electroporation and gene gun methods.

Shixia Wang, Shan Lu, Zu-hu Huang, 2008, Vaccine.

Co-expression of HIV-1 virus-like particles and granulocyte-macrophage colony stimulating factor by GEO-D03 DNA vaccine

E. Wright, Shan Lu, H. Yi, 2012, Human vaccines & immunotherapeutics.

A novel DNA and protein combination COVID-19 vaccine formulation provides full protection against SARS-CoV-2 in rhesus macaques

Zhengrong Hu, Shixia Wang, Shan Lu, 2021, Emerging microbes & infections.

Contribution of TLR4 and MyD88 for adjuvant monophosphoryl lipid A (MPLA) activity in a DNA prime-protein boost HIV-1 vaccine.

Shixia Wang, Shan Lu, E. Lien, 2014, Vaccine.

Genome-Wide Mutant Fitness Profiling Identifies Nutritional Requirements for Optimal Growth of Yersinia pestis in Deep Tissue

R. Baker, Shan Lu, J. Goguen, 2014, mBio.

Generation and characterization of a large panel of murine monoclonal antibodies against vaccinia virus.

G. Zhong, Y. Xiang, Shan Lu, 2011, Virology.

Concurrent Measurement of Dynamic Changes in Viral Load, Serum Enzymes, T Cell Subsets, and Cytokines in Patients with Severe Fever with Thrombocytopenia Syndrome

Shixia Wang, Shan Lu, Ning Liu, 2014, PloS one.

Post-translational intracellular trafficking determines the type of immune response elicited by DNA vaccines expressing Gag antigen of Human Immunodeficiency Virus Type 1 (HIV-1)

A. Rothman, F. Ennis, Shixia Wang, 2013, Human vaccines & immunotherapeutics.

Polyvalent DNA Vaccines Expressing HA Antigens of H5N1 Influenza Viruses with an Optimized Leader Sequence Elicit Cross-Protective Antibody Responses

W. Cao, Shixia Wang, Shan Lu, 2011, PloS one.

Increased Immunogenicity of Human Immunodeficiency Virus gp120 Engineered To Express Galα1-3Galβ1-4GlcNAc-R Epitopes

Shixia Wang, Shan Lu, U. Galili, 2006, Journal of Virology.

Construction and evaluation of replication-defective recombinant optimized triosephosphate isomerase adenoviral vaccination in Schistosoma japonicum challenged mice.

Shan Lu, J. Dai, M. Zeng, 2014, Vaccine.

Structural Comparison of Human Anti-HIV-1 gp120 V3 Monoclonal Antibodies of the Same Gene Usage Induced by Vaccination and Chronic Infection

M. Gorny, X. Kong, Shixia Wang, 2018, Journal of Virology.

The wide utility of rabbits as models of human diseases

L. BenMohamed, G. Kaplan, G. McFadden, 2018, Experimental & Molecular Medicine.

Efficiency of Bridging-Sheet Recruitment Explains HIV-1 R5 Envelope Glycoprotein Sensitivity to Soluble CD4 and Macrophage Tropism

S. Zolla-Pazner, X. Kong, Shixia Wang, 2012, Journal of Virology.

J. Arthos, Shixia Wang, Shan Lu, 2011, Journal of Virology.

Comparison of safety and immunogenicity of purified chick embryo cell vaccine using Zagreb and Essen regimens in patients with category II exposure in China

Shan Lu, Man-Qing Liu, Zhenggang Zhu, 2014, Human vaccines & immunotherapeutics.

Safety comparison of four types of rabies vaccines in patients with WHO category II animal exposure

Shan Lu, Zhenggang Zhu, Yuan-yuan Fang, 2016, Medicine.

Safety, immunogenicity of lyophilized purified vero cell cultured rabies vaccine administered in Zagreb and Essen regimen in post-exposure subjects: A post-marketing, parallel control clinical trial

Shan Lu, Yuan-yuan Fang, Lei Zhang, 2021, Human vaccines & immunotherapeutics.

Rabies post-exposure prophylaxis for a male with severe Henoch Schönlein purpura following rabies vaccination

Shan Lu, Yuan-yuan Fang, Yi Zheng, 2018, Human vaccines & immunotherapeutics.

DNA Immunization

Shixia Wang, Shan Lu, 2013, Current protocols in microbiology.

Rationally Designed Immunogens Targeting HIV-1 gp120 V1V2 Induce Distinct Conformation-Specific Antibody Responses in Rabbits

S. Zolla-Pazner, M. Totrov, Xueling Wu, 2016, Journal of Virology.

The role of follicular helper T cells and the germinal center in HIV-1 gp120 DNA prime and gp120 protein boost vaccination

A. Mondal, A. Dent, Shixia Wang, 2014, Human vaccines & immunotherapeutics.

DNA prime-protein boost using subtype consensus Env was effective in eliciting neutralizing antibody responses against subtype BC HIV-1 viruses circulating in China

K. Hong, Y. Shao, Shixia Wang, 2012, Human vaccines & immunotherapeutics.

Progress on the Induction of Neutralizing Antibodies Against HIV Type 1 (HIV-1)

Shixia Wang, Shan Lu, M. Vaine, 2012, BioDrugs.

Non-neutralizing antibodies targeting the immunogenic regions of HIV-1 envelope reduce mucosal infection and virus burden in humanized mice

S. Zolla-Pazner, Daniel W. Heindel, J. Prévost, 2021, bioRxiv.

Broadly binding and functional antibodies and persisting memory B cells elicited by HIV vaccine PDPHV

G. Ferrari, Shixia Wang, Shan Lu, 2022, npj Vaccines.

Broadly binding and functional antibodies and persisting memory B cells elicited by HIV vaccine PDPHV

G. Ferrari, Shixia Wang, Shan Lu, 2022, npj Vaccines.

DNA priming immunization is more effective than recombinant protein vaccine in eliciting antigen-specific B cell responses

Shixia Wang, Shan Lu, Lu Zhang, 2021, Emerging microbes & infections.

The dynamics of immunoglobulin V-gene usage and clonotype expansion in mice after prime and boost immunizations as analyzed by NGS

Shixia Wang, Shan Lu, Diego J. Farfán-Arribas, 2017, Human vaccines & immunotherapeutics.

Identification of Aim2 as a Sensor for DNA Vaccines

Katherine A. Fitzgerald, Shan Lu, Shixia Wang, 2015, The Journal of Immunology.

Identification of QS-21 as an Inflammasome-activating Molecular Component of Saponin Adjuvants*

Shixia Wang, Shan Lu, E. Lien, 2015, The Journal of Biological Chemistry.

Profiles of Human Serum Antibody Responses Elicited by Three Leading HIV Vaccines Focusing on the Induction of Env-Specific Antibodies

D. Montefiori, M. McElrath, P. Goepfert, 2010, PloS one.

Neutralizing antibody-independent containment of immunodeficiency virus challenges by DNA priming and recombinant pox virus booster immunizations

D. Montefiori, J. Lifson, R. Johnson, 1999, Nature Medicine.

Rabbit Anti-HIV-1 Monoclonal Antibodies Raised by Immunization Can Mimic the Antigen-Binding Modes of Antibodies Derived from HIV-1-Infected Humans

X. Kong, Shixia Wang, Shan Lu, 2013, Journal of Virology.

Immunization of rhesus macaques with a polyvalent DNA prime/protein boost human immunodeficiency virus type 1 vaccine elicits protective antibody response against simian human immunodeficiency virus of R5 phenotype.

J. Mascola, D. Montefiori, Shixia Wang, 2006, Virology.

, Immunogen Design of Antibody Epitopes for HIV-1 Env Platform To Dissect the Diverse Repertoire A Novel Rabbit Monoclonal Antibody

D. Montefiori, Shengqing Wan, Shixia Wang, 2014 .

Preclinical evaluation of cellular immune responses elicited by a polyvalent DNA prime/protein boost HIV-1 vaccine.

Shixia Wang, Shan Lu, R. Pal, 2006, Virology.

Syndrome Coronavirus 2 in Rhesus Glycoprotein of Severe Acute Respiratory Identification of T Cell Epitopes in the Spike

Zhanlong, Shan Lu, Qihan Li, 2021 .

Structure-guided design and immunological characterization of immunogens presenting the HIV-1 gp120 V3 loop on a CTB scaffold.

R. Abagyan, S. Zolla-Pazner, M. Gorny, 2010, Virology.

Nucleic Acid Vaccines

Shixia Wang, Shan Lu, J. Suschak, 2013 .

Clostridium difficile infections in China

Shixia Wang, Shan Lu, K. Jin, 2010, Journal of biomedical research.

infections in China

Shixia Wang, Shan Lu, K. Jin, 2010 .

Factors influencing the development of antibiotic associated diarrhea in ED patients discharged home: risk of administering IV antibiotics.

D. Hoaglin, Shan Lu, Chris Merritt, 2014, The American journal of emergency medicine.

Intramuscular delivery of a cholera DNA vaccine primes both systemic and mucosal protective antibody responses against cholera.

Shixia Wang, Shan Lu, Zu-hu Huang, 2009, Vaccine.

Select gp120 V2 domain specific antibodies derived from HIV and SIV infection and vaccination inhibit gp120 binding to α4β7

A. Fauci, L. Morris, M. Roederer, 2018, PLoS pathogens.

Mouse study of combined DNA/protein COVID-19 vaccine to boost high levels of antibody and cell mediated immune responses

Shan Lu, Zhenglun Liang, Shuying Liu, 2022, Emerging microbes & infections.

Fc Receptor-Mediated Activities of Env-Specific Human Monoclonal Antibodies Generated from Volunteers Receiving the DNA Prime-Protein Boost HIV Vaccine DP6-001

H. Liao, M. Gorny, D. Montefiori, 2016, Journal of Virology.

Rationally Designed Vaccines Targeting the V2 Region of HIV-1 gp120 Induce a Focused, Cross-Clade-Reactive, Biologically Functional Antibody Response

S. Zolla-Pazner, M. Totrov, X. Kong, 2016, Journal of Virology.

Cross-subtype antibody and cellular immune responses induced by a polyvalent DNA prime-protein boost HIV-1 vaccine in healthy human volunteers.

S. Green, A. Rothman, F. Ennis, 2008, Vaccine.

Application of area scaling analysis to identify natural killer cell and monocyte involvement in the GranToxiLux antibody dependent cell‐mediated cytotoxicity assay

Y. Hu, R. Koup, G. Ferrari, 2018, Cytometry. Part A : the journal of the International Society for Analytical Cytology.

Cross-Clade HIV-1 Neutralizing Antibodies Induced with V3-Scaffold Protein Immunogens following Priming with gp120 DNA

S. Zolla-Pazner, M. Totrov, A. Nadas, 2011, Journal of Virology.

Hemagglutinin (HA) Proteins from H1 and H3 Serotypes of Influenza A Viruses Require Different Antigen Designs for the Induction of Optimal Protective Antibody Responses as Studied by Codon-Optimized HA DNA Vaccines

A. García-Sastre, Shixia Wang, Shan Lu, 2006, Journal of Virology.

Timely development of vaccines against SARS-CoV-2

Shan Lu, 2020, Emerging microbes & infections.

Author Correction: The wide utility of rabbits as models of human diseases

Jia Liu, Shan Lu, Neil Christensen, 2018, Experimental & Molecular Medicine.

Immunogenicities of Env glycoproteins from circulating HIV-1 isolates in China focusing on the strategy of "DNA prime plus protein boost".

Z. Wang, Shan Lu, Lu Zhang, 2009, Chinese medical journal.

Select gp120 V2 domain specific antibodies derived from HIV and SIV infection and vaccination inhibit gp120 binding to alpha4beta7

A. Fauci, L. Morris, M. Roederer, 2018 .

Increased immunogenicity of HIV-1 p24 and gp120 following immunization with gp120/p24 fusion protein vaccine expressing alpha-gal epitopes.

Shixia Wang, Shan Lu, U. Galili, 2010, Vaccine.

Profiles of Acute Cytokine and Antibody Responses in Patients Infected with Avian Influenza A H7N9

Yong Liu, Rui Huang, Chao Wu, 2014, PloS one.

1 CROSS-CLADE HIV-1 NEUTRALIZING ANTIBODIES INDUCED WITH 1 V 3-SCAFFOLD PROTEIN IMMUNOGENS FOLLOWING PRIMING WITH gp 120 DNA 2 3 Running Title : Vaccine-induced HIV neutralizing antibodies 4 5

S. Zolla-Pazner, M. Totrov, A. Nadas, 2011 .

Pilot Study on the Use of DNA Priming Immunization to Enhance Y. pestis LcrV-Specific B Cell Responses Elicited by a Recombinant LcrV Protein Vaccine

Shixia Wang, Shan Lu, Wei Li, 2013, Vaccines.

The safety and immunogenicity of an inactivated SARS-CoV-2 vaccine in Chinese adults aged 18–59 years: A phase I randomized, double-blinded, controlled trial

Shan Lu, Changgui Li, Xuanyi Wang, 2021, Vaccine.

Protective immunity induced by rotavirus DNA vaccines.

H. Greenberg, Shan Lu, J. Herrmann, 1997, Vaccine.

Immunogenicity of DNA vaccines expressing human immunodeficiency virus type 1 envelope glycoprotein with and without deletions in the V1/2 and V3 regions.

J. Sodroski, R. Wyatt, D. Montefiori, 1998, AIDS research and human retroviruses.

Glycan Profiles of gp120 Protein Vaccines from Four Major HIV-1 Subtypes Produced from Different Host Cell Lines under Non-GMP or GMP Conditions

M. Ishihara, Shixia Wang, Shan Lu, 2020, Journal of Virology.

Studies of the Neutralizing Activity and Avidity of Anti-Human Immunodeficiency Virus Type 1 Env Antibody Elicited by DNA Priming and Protein Boosting

D. Montefiori, J. Richmond, Shiu-Lok Hu, 1998, Journal of Virology.

HIV-1 Env glycoproteins from two series of primary isolates: replication phenotype and immunogenicity.

J. Richmond, E. Fenyö, Shan Lu, 1997, Virology.

An in-depth investigation of the safety and immunogenicity of an inactivated SARS-CoV-2 vaccine

Yang Gao, H. Yang, Y. Li, 2020, medRxiv.

Antibody responses in COVID-19 patients

Shan Lu, Shuying Liu, 2020, Journal of biomedical research.

Humoral and cellular immunogenecity of DNA vaccine based on hepatitis B core gene in rhesus monkeys.

Zu-hu Huang, Shan Lu, H. Zhuang, 2001, World journal of gastroenterology.

Reduced MyD88 dependency of ISCOMATRIX™ adjuvant in a DNA prime-protein boost HIV vaccine

Shixia Wang, Shan Lu, E. Lien, 2014, Human vaccines & immunotherapeutics.

The Induction of Mucosal Immunity in the Female Genital Tract Using Gene‐Gun Technology Part 1: Antigen Expression

Shan Lu, H. Robinson, Deborah J Anderson, 1995, Annals of the New York Academy of Sciences.

Follicular regulatory T cells repress cytokine production by follicular helper T cells and optimize IgG responses in mice

Hong Liu, A. Dent, Shixia Wang, 2016, European journal of immunology.

A Novel DDB2-ATM Feedback Loop Regulates Human Cytomegalovirus Replication

A. Brass, T. Kowalik, Shixia Wang, 2013, Journal of Virology.

Fc Receptor-Mediated Activities of Env-Specific Human Monoclonal Antibodies Generated from Volunteers Receiving the DNA Prime-Protein Boost HIV Vaccine DP6-001

M. Gorny, D. Montefiori, Shixia Wang, 2016, Journal of Virology.

A Novel Rabbit Monoclonal Antibody Platform To Dissect the Diverse Repertoire of Antibody Epitopes for HIV-1 Env Immunogen Design

D. Montefiori, X. Kong, Shixia Wang, 2013, Journal of Virology.

Identification of two neutralizing regions on the severe acute Identification of two neutralizing regions on the severe acute respiratory syndrome coronavirus spike glycoprotein produced respiratory syndrome coronavirus spike glycoprotein produced from the mammalian expression system from the mammal

Shan Lu, Pavlo V. Sakhatskyy, John M. Lawrence, 2022 .

Focusing the immune response on the V3 loop of HIV-1 gp120 induces cross-clade neutralizing

S. Zolla-Pazner, Shixia Wang, Shan Lu, 2006, Retrovirology.

Involvement of the Aim2 inflammasome pathway in generating antibody responses elicited by DNA vaccination. (P4313)

Shixia Wang, Shan Lu, K. Fitzgerald, 2013, The Journal of Immunology.

Measurement of neutralizing antibody responses against H5N1 clades in immunized mice and ferrets using pseudotypes expressing influenza hemagglutinin and neuraminidase

Boping Zhou, V. Deubel, P. Buchy, 2009, Vaccine.