B. Holzmann

K. Tsujikawa, S. Wehner, B. Holzmann, 2015, Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society.

Interleukin-10 and -12 Predict Chemotherapy-Associated Toxicity in Esophageal Adenocarcinoma

H. Friess, W. Knoefel, B. Holzmann, 2010, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

Selective defects of T lymphocyte function in patients with lethal intraabdominal infection.

J. Siewert, B. Holzmann, C. Heidecke, 1999, American journal of surgery.

Inhibition of Interleukin-22 Attenuates Bacterial Load and Organ Failure during Acute Polymicrobial Sepsis

B. Holzmann, H. Weighardt, G. Weber, 2007, Infection and Immunity.

Synthesis and Structure−Activity Relationship of Mannose-Based Peptidomimetics Selectively Blocking Integrin α4β7 Binding to Mucosal Addressin Cell Adhesion Molecule-1

H. Kessler, B. Holzmann, A. Schuster, 2003 .

Distinct but overlapping epitopes are involved in alpha 4 beta 7-mediated adhesion to vascular cell adhesion molecule-1, mucosal addressin-1, fibronectin, and lymphocyte aggregation.

T. Yoshino, E. Butcher, A. Hamann, 1994, Journal of immunology.

COMBINED IMMUNOSUPPRESSIVE AND ANTIBIOTIC THERAPY IMPROVES BACTERIAL CLEARANCE AND SURVIVAL OF POLYMICROBIAL SEPTIC PERITONITIS

B. Holzmann, V. Assfalg, N. Hüser, 2010, Shock.

Hyperinflammation in Septic Peritonitis Type I IFN Modulates Host Defense and Late

C. Bogdan, B. Holzmann, H. Weighardt, 2006 .

Cloning and expression of mouse integrin beta p(beta 7): a functional role in Peyer's patch-specific lymphocyte homing.

M. C. Hu, I. Weissman, M. C. Hu, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Regulation and function of the CGRP receptor complex in human granulopoiesis.

C. Peschel, B. Holzmann, U. Keller, 2002, Experimental hematology.

Activated α4 Integrins are Preferentially Expressed on Immature Thymocytes and Activated T Cells

J. Kearney, F. Seibold, D. Erle, 2002, Developmental immunology.

Endotoxin-Induced Lung Inflammation Is Independent of the Complement Membrane Attack Complex

B. Holzmann, C. Heidecke, B. Neumann, 2000, Infection and Immunity.

Neoadjuvant treatment of esophageal cancer: Immunosuppression following combined radiochemotherapy.

M. Feith, J. Siewert, B. Holzmann, 2002, Surgery.

Reduced notch activity is associated with an impaired marginal zone B cell development and function in Sly1 mutant mice.

B. Reis, K. Pfeffer, B. Holzmann, 2009, Molecular immunology.

alpha 4 integrins and tumor metastasis.

B. Holzmann, M. Bittner, U. Gosslar, 1998, Current topics in microbiology and immunology.

Thyroglobulin, the major and obligatory exportable protein of thyroid follicle cells, carries the lysosomal recognition marker mannose‐6‐phosphate.

V. Herzog, B. Holzmann, W. Neumüller, 1987, The EMBO journal.

The neuropeptide receptor subunit RAMP1 constrains the innate immune response during acute pancreatitis in mice.

R. Schmid, B. Holzmann, N. Hüser, 2019, Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.].

Critical role of nitric oxide for proliferation and apoptosis of bone-marrow cells under septic conditions

B. Holzmann, J. Stadler, W. Barthlen, 2000, Annals of Hematology.

Intact LFA-1 deactivation promotes T-cell activation and rejection of cardiac allograft.

B. Holzmann, N. Hüser, A. Fasan, 2010, International immunology.

Sequence motifs in the integrin alpha 4 cytoplasmic tail required for regulation of in vivo expansion of murine lymphoma cells.

B. Holzmann, M. Bittner, A. Luz, 1998, Journal of immunology.

Lymphocyte homing receptors.

I. Weissman, M. C. Hu, B. Holzmann, 1992, Cold Spring Harbor symposia on quantitative biology.

Induction of acute inflammatory lung injury by staphylococcal enterotoxin B.

B. Engelhardt, B. Holzmann, H. Wagner, 1997, Journal of immunology.

Lymph node (but not spleen) invasion by murine lymphoma is both CD44- and hyaluronate-dependent.

M. Zahalka, B. Holzmann, D. Naor, 1995, Journal of immunology.

Procalcitonin can be used for monitoring sepsis in patients with medullary thyroid carcinoma.

H. Friess, R. Rosenberg, M. Maak, 2009, Thyroid : official journal of the American Thyroid Association.

Modulation of immune responses by the neuropeptide CGRP

B. Holzmann, 2013, Amino Acids.

Triggering of L-selectin (gp90MEL-14) induces homotypic lymphocyte adhesion by a mechanism independent of LFA-1.

B. Holzmann, U. Strauch, 1993, International immunology.

Increased susceptibility to postoperative sepsis in patients with impaired monocyte IL-12 production.

J. Siewert, K. Heeg, B. Holzmann, 1998, Journal of immunology.

Design, Synthesis, and Biological Evaluation of α4 β1 Integrin Antagonists Based on β-D-Mannose as Rigid Scaffold.

H. Kessler, B. Holzmann, D. Gottschling, 2001, Angewandte Chemie.

Current and Future Concepts of Abdominal Sepsis

J. Siewert, B. Holzmann, H. Weighardt, 2004, World Journal of Surgery.

Essential Role of Gamma Interferon in Survival of Colon Ascendens Stent Peritonitis, a Novel Murine Model of Abdominal Sepsis

J. Siewert, K. Pfeffer, B. Holzmann, 1998, Infection and Immunity.

DIFFERENTIAL REGULATION OF SYSTEMIC IL-18 AND IL-12 RELEASE DURING POSTOPERATIVE SEPSIS: HIGH SERUM IL-18 AS AN EARLY PREDICTIVE INDICATOR OF LETHAL OUTCOME

K. Ulm, J. Siewert, B. Holzmann, 2002, Shock.

Normal T lymphocyte and monocyte function after minimally invasive surgery

H. Feußner, J. Siewert, B. Holzmann, 1998, Surgical Endoscopy.

Discrimination between benign and malignant cells of melanocytic lineage by two novel antigens, a glycoprotein with a molecular weight of 113,000 and a protein with a molecular weight of 76,000.

J. Lehmann, J. Johnson, G. Riethmüller, 1987, Cancer research.

Leukocyte Integrins in the Immune System and Malignant Disease

B. Holzmann, H. Wagner, 1998, Current Topics in Microbiology and Immunology.

Integrin subunit CD18 Is the T-lymphocyte receptor for the Helicobacter pylori vacuolating cytotoxin.

D. Busch, R. Osicka, P. Šebo, 2008, Cell host & microbe.

Organ-specific requirements for cell adhesion molecules during lymphoma cell dissemination.

Ronit Vogt Sionov, M. Zahalka, B. Holzmann, 1998, Current topics in microbiology and immunology.

Role of alpha 4-integrins in lymphocyte homing to mucosal tissues in vivo.

E. Butcher, A. Hamann, B. Holzmann, 1994, Journal of immunology.

Expression of the mitotic checkpoint gene MAD2L2 has prognostic significance in colon cancer

Robert Rosenberg, R. Rosenberg, J. Friederichs, 2007, International journal of cancer.

Notch and TLR signaling coordinate monocyte cell fate and inflammation

H. Haller, T. Sparwasser, B. Holzmann, 2020, bioRxiv.

Prognostic significance of downregulated expression of the candidate tumour suppressor gene SASH1 in colon cancer

R. Rosenberg, J. Friederichs, J. Siewert, 2006, British Journal of Cancer.

Importance of integrin LFA-1 deactivation for the generation of immune responses

D. Busch, N. Hogg, B. Engelhardt, 2005, The Journal of experimental medicine.

RhoH is important for positive thymocyte selection and T-cell receptor signaling.

M. Sixt, J. Ellwart, B. Holzmann, 2007, Blood.

CC chemokine receptor 2 regulates leukocyte recruitment and IL‐10 production during acute polymicrobial sepsis

M. Mack, B. Holzmann, H. Weighardt, 2004, European journal of immunology.

Anti-oncogenic activity of signalling-defective epidermal growth factor receptor mutants

E. Wagner, A. Ullrich, J. Schlessinger, 1992, Molecular and cellular biology.

Telomere length and human telomerase reverse transcriptase expression as markers for progression and prognosis of colorectal carcinoma.

Axel Hoos, Kurt Ulm, Martin Werner, 2004, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Immune protection against septic peritonitis in endotoxin‐primed mice is related to reduced neutrophil apoptosis

B. Holzmann, H. Weighardt, Carolin Feterowski, 2001, European journal of immunology.

Inflammatory cell infiltrates in human melanoma at different stages of tumor progression

E. Bröcker, B. Holzmann, E. Macher, 1988, International journal of cancer.

Micrometastatic cancer cells in bone marrow: in vitro detection with anti-cytokeratin and in vivo labeling with anti-17-1A monoclonal antibodies.

G. Schlimok, G. Riethmüller, B. Holzmann, 1987, Proceedings of the National Academy of Sciences of the United States of America.

IL-22-Mediated Tumor Growth Reduction Correlates with Inhibition of ERK1/2 and AKT Phosphorylation and Induction of Cell Cycle Arrest in the G2-M Phase

Markus Essler, Florian C Gaertner, Georg F Weber, 2006, The Journal of Immunology.

for Host Defense in Septic Peritonitis Critical Role of Kupffer Cell-Derived IL-10

X. Zheng, B. Holzmann, S. Maier, 2013 .

Modulation of immune responses by the neuropeptide CGRP

B. Holzmann, 2011, Amino Acids.

The Human WD Repeat Protein WAIT-1 Specifically Interacts with the Cytoplasmic Tails of β7-Integrins*

B. Holzmann, W. Kolanus, M. Bittner, 1998, The Journal of Biological Chemistry.

A dual role for hepatocyte-intrinsic canonical NF-κB signaling in virus control

M. Binder, M. Karin, M. Heikenwalder, 2020, Zeitschrift für Gastroenterologie.

Attack Complex Independent of the Complement Membrane Endotoxin-Induced Lung Inflammation Is

B. Holzmann, C. Heidecke, B. Neumann, 2000 .

α4β7 integrin mediates lymphocyte binding to the mucosal vascular addressin MAdCAM-1

E. Berg, I. Weissman, E. Butcher, 1993, Cell.

Systemic neuropeptide levels as predictive indicators for lethal outcome in patients with postoperative sepsis

J. Siewert, B. Holzmann, C. Heidecke, 2002, Critical care medicine.

Impact of experimental peritonitis on bone marrow cell function.

K. Pfeffer, B. Holzmann, C. Heidecke, 1999, Surgery.

MyD88 signaling in dendritic cells and the intestinal epithelium controls immunity against intestinal infection with C. rodentium

T. Sparwasser, B. Holzmann, T. Strowig, 2017, PLoS pathogens.

Functional cloning of ARM-1, an adhesion-regulating molecule upregulated in metastatic tumor cells

U. Weidle, B. Holzmann, H. Weighardt, 2004, Clinical & Experimental Metastasis.

Identification of a TLR4‐ and TRIF‐dependent activation program of dendritic cells

B. Beutler, B. Holzmann, K. Hoebe, 2004, European journal of immunology.

Sepsis after major visceral surgery is associated with sustained and interferon-gamma-resistant defects of monocyte cytokine production.

B. Holzmann, C. Heidecke, S. Maier, 2000, Surgery.

A20 prevents inflammasome-dependent arthritis by inhibiting macrophage necroptosis through its ZnF7 ubiquitin-binding domain

G. Kollias, S. Uemura, M. Pasparakis, 2019, Nature Cell Biology.

Cell-type specific MyD88 signaling is required for intestinal tumor initiation and progression to malignancy

K. Janssen, B. Holzmann, Anja Conrad, 2018, Oncoimmunology.

Toll‐like receptor 3 expression in myeloid cells is essential for efficient regeneration after acute pancreatitis in mice

R. Schmid, B. Holzmann, K. Steiger, 2021, European journal of immunology.

Organ-Specific Role of MyD88 for Gene Regulation during Polymicrobial Peritonitis

B. Holzmann, H. Weighardt, J. Mages, 2006, Infection and Immunity.

Improved host defense against septic peritonitis in mice lacking MyD88 and TRIF is linked to a normal interferon response

B. Holzmann, D. Reim, Olivia Prazeres da Costa, 2011, Journal of leukocyte biology.

Tumor progression in human malignant melanoma: Five stages defined by their antigenic phenotypes

J. Lehmann, D. Ruiter, E. Bröcker, 1987, International journal of cancer.

Cytochrome P450 activity mirrors nitric oxide levels in postoperative sepsis: predictive indicators of lethal outcome.

M. Schwaiger, J. Siewert, B. Holzmann, 2007, Surgery.

Gene expression profiles of different clinical stages of colorectal carcinoma: toward a molecular genetic understanding of tumor progression

R. Rosenberg, J. Friederichs, H. Nekarda, 2005, International Journal of Colorectal Disease.

Expression of osteopontin, a target gene of de‐regulated Wnt signaling, predicts survival in colon cancer

R. Rosenberg, J. Friederichs, J. Siewert, 2007, International journal of cancer.

Bacterial superantigens induce rapid and T cell receptor V beta-selective down-regulation of L-selectin (gp90Mel-14) in vivo.

K. Heeg, B. Holzmann, H. Wagner, 1993, Journal of immunology.

Predominant role of alpha 4-integrins for distinct steps of lymphoma metastasis.

A. Hamann, B. Holzmann, D. Naor, 1996, Proceedings of the National Academy of Sciences of the United States of America.

APACHE II and Mannheim Peritonitis Index (MPI) fail to predict lethality in septic peritonitis in immunosuppressed solid organ transplant recipients

B. Holzmann, V. Assfalg, N. Hüser, 2013, European Surgery.

Identification of a murine Peyer's patch—specific lymphocyte homing receptor as an integrin molecule with an α chain homologous to human VLA-4α

I. Weissman, B. Holzmann, B. McIntyre, 1989, Cell.

[Immune paralysis of T-lymphocytes and monocytes in postoperative abdominal sepsis. Correlation of immune function with survival].

B. Holzmann, C. Heidecke, H. Weighardt, 2000, Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen.

Cloning and expression of cDNAs for the alpha subunit of the murine lymphocyte-Peyer's patch adhesion molecule

I. Weissman, M. C. Hu, Y. Takada, 1991, The Journal of cell biology.

Mixed antagonist response and sepsis severity-dependent dysbalance of pro- and anti-inflammatory responses at the onset of postoperative sepsis.

H. Friess, B. Holzmann, V. Assfalg, 2012, Immunobiology.

Impaired Monocyte IL-12 Production Before Surgery as a Predictive Factor for the Lethal Outcome of Postoperative Sepsis

K. Ulm, J. Siewert, B. Holzmann, 2002, Annals of surgery.

Expression of type I interferon by splenic macrophages suppresses adaptive immunity during sepsis

C. Coch, S. Wehner, R. Zawatzky, 2012, The EMBO journal.

Use of procalcitonin for early prediction of lethal outcome of postoperative sepsis.

K. Ulm, J. Siewert, B. Holzmann, 2007, American journal of surgery.

Procalcitonin ratio and on-demand relaparotomy for septic peritonitis: validation of the focus index (FI)

H. Friess, Petra Wolf, B. Holzmann, 2016, Surgery Today.

Molecular analysis of the physiological and pathophysiological role of α4-integrins

B. Holzmann, G. Kilger, 1995, Journal of Molecular Medicine.

Effects of functional Toll‐like receptor‐4 mutations on the immune response to human and experimental sepsis

K. Ulm, B. Holzmann, H. Weighardt, 2003, Immunology.

Distinct binding specificities of integrins α4β7 (LPAM-1), α4β1 (VLA-4), and αIELβ7

B. Holzmann, J. Clements, A. Lifka, 1994 .

Distinct binding specificities of integrins alpha 4 beta 7 (LPAM-1), alpha 4 beta 1 (VLA-4), and alpha IEL beta 7.

B. Holzmann, J. Clements, U. Strauch, 1994, International immunology.

Cytosolic nucleic acid sensors of the innate immune system promote liver regeneration after partial hepatectomy

H. Friess, B. Holzmann, N. Hüser, 2018, Scientific Reports.

Gut microbiota promote liver regeneration through hepatic membrane phospholipid biosynthesis.

F. Lohöfer, G. Liebisch, A. Bleich, 2023, Journal of hepatology.

TRIF Signaling Stimulates Translation of TNF-α mRNA via Prolonged Activation of MK2

M. Gaestel, B. Holzmann, H. Weighardt, 2010, The Journal of Immunology.

Reduced expression of a gene proliferation signature is associated with enhanced malignancy in colon cancer

A. Reeve, J. Friederichs, Sarah Song, 2008, British Journal of Cancer.

[Indicators for early prediction of outcome in sepsis].

J. Siewert, B. Holzmann, A. Novotny, 2005, Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen.

Differential Regulation of Integrin-dependent Binding to Domains 1 and 4 of Vascular Cell Adhesion Molecule-1 (*)

D. Vestweber, L. Needham, B. Holzmann, 1995, The Journal of Biological Chemistry.

Amino acid residues required for binding of vascular cell adhesion molecule-1 to integrin α 4 β 7

B. Holzmann, J. Clements, G. Kilger, 1997 .

The Peyer's patch homing receptor.

I. Weissman, M. C. Hu, B. Holzmann, 1993, Current topics in microbiology and immunology.

Identification ofa 107-kDGlycoproteinthatMediates Adhesionbetween StromalCellsand Hematolymphoid Cells

I. Weissman, B. Holzmann, Y. Katsura, 1991 .

Blood interleukin 12 as preoperative predictor of fatal postoperative sepsis after neoadjuvant radiochemotherapy

K. Ulm, J. Siewert, B. Holzmann, 2006, The British journal of surgery.

RESPIRATORY BURST AND PHAGOCYTIC ACTIVITY IN PATIENTS WITH SEPSIS AFTER ABDOMINAL SURGERY: 179

J. Siewert, B. Holzmann, J. Stadler, 1997 .

ROLE OF T CELLS FOR CYTOKINE PRODUCTION AND OUTCOME IN A MODEL OF ACUTE SEPTIC PERITONITIS

B. Holzmann, H. Weighardt, D. Reim, 2009, Shock.

Antiinflammatory activities of CGRP modulating innate immune responses in health and disease.

B. Holzmann, 2013, Current protein & peptide science.

β-D-Mannose Based Peptidomimetics in the Design of α4ß1 and α4β7 Antagonists

H. Kessler, B. Holzmann, A. Schuster, 2001 .

Design and Synthesis of Potent and Selective a 4 7 Integrin Antagonists

H. Kessler, B. Holzmann, M. Semmrich, 2001 .

De novo expression of intercellular-adhesion molecule 1 in melanoma correlates with increased risk of metastasis.

G. Riethmüller, B. Holzmann, Judith P. Johnson, 1989, Proceedings of the National Academy of Sciences of the United States of America.

[Pneumonia due to a rare atypical Mycobacterium in AIDS].

M. Classen, B. Holzmann, W. Huber, 1993, Deutsche Medizinische Wochenschrift.

Animal Models of sepsis: setting the stage

M. Sitkovsky, B. Holzmann, J. Buras, 2005 .

Dendritic cells coordinate innate immunity via MyD88 signaling to control Listeria monocytogenes infection.

A. Kühl, T. Sparwasser, B. Holzmann, 2014, Cell reports.

Requirement of MyD88 signaling in keratinocytes for Langerhans cell migration and initiation of atopic dermatitis‐like symptoms in mice

B. Holzmann, H. Weighardt, I. Förster, 2016, European journal of immunology.

[Receptors and signal proteins of the innate immune system as new targets in sepsis therapy. Reprogramming of the immune response].

B. Holzmann, C. Heidecke, H. Weighardt, 2003, Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen.