J. Charbonnier

发表

Crystal structure of a Staphylococcus aureus protein A domain complexed with the Fab fragment of a human IgM antibody: structural basis for recognition of B-cell receptors and superantigen activity.

M. Taussig, M. Graille, E. Stura, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Crystallization of macromolecular complexes : stoichiometric variation screening

M. Taussig, M. Graille, E. Stura, 2001 .

Clickable Bambusurils to Access Multivalent Architectures.

J. Charbonnier, P. Thuéry, B. Kuhnast, 2020, Organic letters.

Macromolecular interactions in vitro, comparing classical and novel approaches

A. Velázquez‐Campoy, P. Soule, M. Aumont-Nicaise, 2021, European Biophysics Journal.

An XRCC4 mutant mouse, a model for human X4 syndrome, reveals interplays with Xlf, PAXX, and ATM in lymphoid development

J. Charbonnier, I. Callebaut, F. Boussin, 2021, eLife.

The checkpoint Saccharomyces cerevisiae Rad9 protein contains a tandem tudor domain that recognizes DNA

B. Alpha-Bazin, S. Zinn-Justin, B. Gilquin, 2007, Nucleic acids research.

Structure of the MutLα C-terminal domain reveals how Mlh1 contributes to Pms1 endonuclease site

B. Gilquin, J. Charbonnier, Pierre Legrand, 2013, Nature Structural &Molecular Biology.

FAN1-MLH1 interaction affects repair of DNA interstrand cross-links and slipped-CAG/CTG repeats

R. Guérois, M. Altmeyer, Mohiuddin Mohiuddin, 2021, Science Advances.

Cryo-EM of NHEJ supercomplexes provides insights into DNA repair

T. Blundell, D. Chirgadze, S. Hardwick, 2021, Molecular cell.

Autocyclized and oxidized forms of SCR7 induce cancer cell death by inhibiting nonhomologous DNA end joining in a Ligase IV dependent manner

J. Charbonnier, Supriya V. Vartak, S. Raghavan, 2018, The FEBS journal.

Mitochondrial targeting of human 8-oxoguanine DNA glycosylase hOGG1 is impaired by a somatic mutation found in kidney cancer.

J. Radicella, J. Charbonnier, S. Boiteux, 2002, DNA repair.

Crystallization of macromolecular complexes: combinatorial complex crystallization

M. Graille, E. Stura, J. Charbonnier, 2001 .

Concerted action of the MutLβ heterodimer and Mer3 helicase regulates the global extent of meiotic gene conversion

R. Guérois, B. Llorente, D. Loew, 2017, eLife.

Genetic Evidence for the Involvement of Mismatch Repair Proteins, PMS2 and MLH3, in a Late Step of Homologous Recombination.

R. Guérois, Mohiuddin Mohiuddin, J. Andreani, 2020, The Journal of biological chemistry.

Identification of the periplasmic DNA receptor for natural transformation of Helicobacter pylori

D. Rao, J. Radicella, J. Charbonnier, 2019, Nature Communications.

The translesion DNA polymerases Pol ζ and Rev1 are activated independently of PCNA ubiquitination upon UV radiation in mutants of DNA polymerase δ

J. Charbonnier, X. Veaute, Émilie Ma, 2017, PLoS genetics.

Molecular basis of the dual role of the Mlh1-Mlh3 endonuclease in MMR and in meiotic crossover formation

R. Guérois, J. Andreani, J. Charbonnier, 2021, Proceedings of the National Academy of Sciences.

NAD Binding Induces Conformational Changes in Rho ADP-ribosylating Clostridium botulinum C3 Exoenzyme*

J. Teulon, A. Ménez, E. Stura, 2002, The Journal of Biological Chemistry.

Crystallization and halide phasing of the C-terminal domain of human KIN17.

S. Zinn-Justin, E. Stura, J. Charbonnier, 2006, Acta crystallographica. Section F, Structural biology and crystallization communications.

pH Influences on the Crystal Structures and Mechanistic Properties of a Hydrolytic Antibody

B. Golinelli‐Pimpaneau, J. Charbonnier, Marcel Knossow, 1996 .

Genetic evidence for the involvement of mismatch repair proteins, PMS2 and MLH3, in a late step of homologous recombination.

R. Guérois, Mohiuddin Mohiuddin, J. Andreani, 2020, The Journal of biological chemistry.

Aprolactin-releasing peptide in thebrain

O. Nishimura, S. Hinuma, J. Charbonnier, 2022 .

Measurements of Protein-DNA Complexes Interactions by Isothermal Titration Calorimetry (ITC) and Microscale Thermophoresis (MST).

M. Aumont-Nicaise, M. Desmadril, J. Charbonnier, 2021, Methods in molecular biology.

Identification and structural basis of the reaction catalyzed by CYP121, an essential cytochrome P450 in Mycobacterium tuberculosis

O. Lequin, J. Charbonnier, J. Pernodet, 2009, Proceedings of the National Academy of Sciences.

Plugged into the Ku-DNA hub: The NHEJ network.

J. Charbonnier, M. Modesti, P. Frit, 2019, Progress in biophysics and molecular biology.

A Small Compound Targeting Prohibitin with Potential Interest for Cognitive Deficit Rescue in Aging mice and Tau Pathology Treatment

Y. Hérault, L. Meijer, J. Charbonnier, 2020, Scientific Reports.

Design of a Gag pentapeptide analogue that binds human cyclophilin A more efficiently than the entire capsid protein: new insights for the development of novel anti-HIV-1 drugs.

A. Ménez, J. Charbonnier, M. Moutiez, 2000, Journal of medicinal chemistry.

Dual functions of the Hsm3 protein in chaperoning and scaffolding regulatory particle subunits during the proteasome assembly

R. Guérois, N. Richet, F. Ochsenbein, 2012, Proceedings of the National Academy of Sciences.

Mechanism of in vivo activation of the MutLγ-Exo1 complex for meiotic crossover formation

S. Keeney, R. Guérois, F. Klein, 2019, bioRxiv.

Hug1 is an intrinsically disordered protein that inhibits ribonucleotide reductase activity by directly binding Rnr2 subunit

N. Richet, F. Ochsenbein, J. Charbonnier, 2014, Nucleic acids research.

Hug 1 is an intrinsically disordered protein that inhibits ribonucleotide reductase activity by directly binding Rnr 2 subunit

N. Richet, F. Ochsenbein, J. Charbonnier, 2014 .

The Multifaceted Roles of Ku70/80

J. Charbonnier, M. Le Du, V. Ropars, 2021, International journal of molecular sciences.

Tandem regulation of MutS activity by ATP and DNA during MMR initiation

J. Charbonnier, 2022, Nature Structural & Molecular Biology.

Structural, thermodynamic, and cellular characterization of human centrin 2 interaction with xeroderma pigmentosum group C protein.

S. Miron, C. Craescu, J. Charbonnier, 2007, Journal of molecular biology.

Structural characterization of filaments formed by human Xrcc4–Cernunnos/XLF complex involved in nonhomologous DNA end-joining

R. Guérois, P. Revy, E. Le Cam, 2011, Proceedings of the National Academy of Sciences.

Exo1 recruits Cdc5 polo kinase to MutLγ to ensure efficient meiotic crossover formation

S. Keeney, R. Guérois, F. Klein, 2020, Proceedings of the National Academy of Sciences.

RNA:DNA hybrids from Okazaki fragments contribute to establish the Ku-mediated barrier to replication-fork degradation.

J. Charbonnier, S. Lambert, Anusha Chaudhuri, 2023, Molecular cell.

Structural analysis of the Smad2-MAN1 interaction that regulates transforming growth factor-β signaling at the inner nuclear membrane.

Wei Wu, S. Zinn-Justin, B. Gilquin, 2010, Biochemistry.

Bi-directional routing of DNA mismatch repair protein human exonuclease 1 to replication foci and DNA double strand breaks.

L. Rasmussen, V. Bohr, F. Nielsen, 2011, DNA repair.

C-terminal region of bacterial Ku controls DNA bridging, DNA threading and recruitment of DNA ligase D for double strand breaks repair

P. Roblin, E. Le Cam, P. Noirot, 2016, Nucleic acids research.

XLF and APLF bind Ku80 at two remote sites to ensure DNA repair by non-homologous end joining

C. Delteil, R. Guérois, E. Le Cam, 2018, Nature Structural & Molecular Biology.

The helicase FBH1 is tightly regulated by PCNA via CRL4(Cdt2)-mediated proteolysis in human cells

J. Charbonnier, P. Kannouche, B. Lopez, 2013, Nucleic acids research.

A Recurrent Activating Missense Mutation in Waldenström Macroglobulinemia Affects the DNA Binding of the ETS Transcription Factor SPI1 and Enhances Proliferation.

O. Elemento, P. Vyas, F. Cosset, 2019, Cancer discovery.

Delineation of the Xrcc4-interacting Region in the Globular Head Domain of Cernunnos/XLF*

R. Guérois, P. Revy, J. Mornon, 2010, The Journal of Biological Chemistry.

Insights from a decade of biophysical studies on MutL: Roles in strand discrimination and mismatch removal.

A. Guarné, J. Charbonnier, Alba Guarné, 2015, Progress in biophysics and molecular biology.

Probing structural and motional features of the C-terminal part of the Human Centrin 2/P17-XPC microcrystalline complex by solid-state NMR spectroscopy.

G. Bodenhausen, J. Charbonnier, L. Duma, 2012, The journal of physical chemistry. B.

Stable interactions between DNA polymerase δ catalytic and structural subunits are essential for efficient DNA repair.

S. Gangloff, J. Charbonnier, C. Dhérin, 2010, DNA repair.

B. Golinelli‐Pimpaneau, J. Charbonnier, Marcel Knossow, 1997, Biochimie.

X-Ray structures of two families of hydrolytic antibodies

B. Golinelli‐Pimpaneau, Z. Eshhar, J. Charbonnier, 1998 .

X-ray structures of a hydrolytic antibody and of complexes elucidate catalytic pathway from substrate binding and transition state stabilization through water attack and product release.

Z. Eshhar, J. Charbonnier, Marcel Knossow, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Structural Convergence in the Active Sites of a Family of Catalytic Antibodies

Dan S. Tawfik, S. Kim, B. Golinelli‐Pimpaneau, 1997, Science.

Highly specific anti-estradiol antibodies: structural characterisation and binding diversity.

S. Zinn-Justin, A. Ménez, B. Gilquin, 2002, Journal of molecular biology.

Exonuclease I-dependent Mismatch Repair Binding Site of Mlh1 Required for Characterization of a Highly Conserved Supplemental Material

L. Rasmussen, S. Zinn-Justin, B. Gilquin, 2008 .

Engineering cyclophilin into a proline-specific endopeptidase

A. Ménez, J. Charbonnier, M. Moutiez, 1998, Nature.

Mechanism of inactivation of a catalytic antibody by p-nitrophenyl esters.

B. Golinelli‐Pimpaneau, Z. Eshhar, J. Charbonnier, 1997, European journal of biochemistry.

Crystal structure of the complex of a catalytic antibody Fab fragment with a transition state analog: structural similarities in esterase-like catalytic antibodies.

B. Golinelli‐Pimpaneau, Z. Eshhar, J. Charbonnier, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Dynamics of Ku and bacterial non-homologous end-joining characterized using single DNA molecule analysis

R. Guérois, J. Charbonnier, F. Westerlund, 2021, Nucleic acids research.

A histidine in the beta-CASP domain of Artemis is critical for its full in vitro and in vivo functions.

M. Lieber, A. Fischer, J. Mornon, 2009, DNA Repair.

XLF and APLF bind Ku80 at two remote sites to ensure DNA repair by non-homologous end joining

C. Delteil, J. Yu, R. Guérois, 2018, Nature Structural & Molecular Biology.

PAXX Is an Accessory c-NHEJ Factor that Associates with Ku70 and Has Overlapping Functions with XLF.

J. Charbonnier, S. Audebert, M. Modesti, 2016, Cell reports.

Catalytic and DNA-binding properties of the human Ogg1 DNA N-glycosylase/AP lyase: biochemical exploration of H270, Q315 and F319, three amino acids of the 8-oxoguanine-binding pocket.

J. Charbonnier, P. A. van der Kemp, S. Boiteux, 2004, Nucleic acids research.

Complex between Peptostreptococcus magnus protein L and a human antibody reveals structural convergence in the interaction modes of Fab binding proteins.

S. Bottomley, M. Taussig, M. Graille, 2001, Structure.

Mechanism of MRX inhibition by Rif2 at telomeres

S. Zinn-Justin, P. Cuniasse, S. Miron, 2021, Nature Communications.

Dual expression system suitable for high-throughput fluorescence-based screening and production of soluble proteins.

S. Zinn-Justin, A. Ménez, J. Charbonnier, 2005, Journal of proteome research.

A B-cell superantigen that targets B-1 lymphocytes.

M. Graille, E. Stura, A. Corper, 2000, Current topics in microbiology and immunology.

Regulation of the MLH1–MLH3 endonuclease in meiosis

Joao Matos, J. Charbonnier, Aurore Sanchez, 2020, Nature.

Large-Scale Production of Microcrystals and Precipitates of Proteins and Their Complexes

G. Bodenhausen, J. Charbonnier, L. Duma, 2012 .

XLF and APLF bind Ku80 at two remote sites to ensure DNA repair by non-homologous end joining

C. Delteil, J. Yu, R. Guérois, 2018, Nature Structural & Molecular Biology.

Cyclodipeptide synthases, a family of class-I aminoacyl-tRNA synthetase-like enzymes involved in non-ribosomal peptide synthesis

J. Charbonnier, J. Seguin, J. Pernodet, 2011, Nucleic acids research.

Nonribosomal peptide synthesis in animals: the cyclodipeptide synthase of Nematostella.

J. Charbonnier, J. Seguin, J. Pernodet, 2011, Chemistry & biology.

Regulation of the MLH1–MLH3 endonuclease in meiosis

Joao Matos, J. Charbonnier, Aurore Sanchez, 2020, Nature.

The FIGNL1-FIRRM complex is required to complete meiotic recombination in the mouse and prevents massive DNA damage-independent RAD51 and DMC1 loading

J. Charbonnier, J. Cau, B. de Massy, 2024, bioRxiv.

A Small Compound Targeting Prohibitin with Potential Interest for Cognitive Deficit Rescue in Aging mice and Tau Pathology Treatment

Y. Hérault, L. Meijer, J. Charbonnier, 2020, Scientific Reports.

Structure-based secondary structure-independent approach to design protein ligands: Application to the design of Kv1.2 potassium channel blockers.

A Joly, P Cuniasse, M. Lefranc, 2006, Journal of the American Chemical Society.

Cryo-EM structure of a DNA-PK trimer: higher order oligomerisation in NHEJ.

T. Blundell, D. Chirgadze, S. Hardwick, 2023, Structure.

On the role of the cis‐proline residue in the active site of DsbA

E. Stura, J. Charbonnier, M. Moutiez, 2008, Protein science : a publication of the Protein Society.

PAXX binding to the NHEJ machinery explains functional redundancy with XLF

T. Blundell, A. P. Pandurangan, S. Hardwick, 2023, Science advances.

A histidine in the beta-CASP domain of Artemis is critical for its full in vitro and in vivo functions.

M. Lieber, A. Fischer, J. Mornon, 2009, DNA repair.

Characterization of a Highly Conserved Binding Site of Mlh1 Required for Exonuclease I-Dependent Mismatch Repair

L. Rasmussen, S. Zinn-Justin, B. Gilquin, 2008, Molecular and Cellular Biology.

Identification and structural basis of the reaction catalyzed by CYP121, an essential cytochrome P450 in Mycobacterium tuberculosis

O. Lequin, J. Charbonnier, J. Pernodet, 2009, Proceedings of the National Academy of Sciences.

Crossreactivity, efficiency and catalytic specificity of an esterase-like antibody.

Z. Eshhar, J. Charbonnier, Marcel Knossow, 1998, Journal of molecular biology.

STRUCTURES OF ESTERASE-LIKE CATALYTIC ANTIBODIES

Z. Eshhar, J. Charbonnier, Marcel Knossow, 1999 .

Ku-binding motifs in RAG2, XLF, PAXX and MRI support functional redundancy during V(D)J recombination

D. Loew, F. Dingli, J. Charbonnier, 2023, bioRxiv.

Uncoupling programmed DNA cleavage and repair scrambles the Paramecium somatic genome.

J. Charbonnier, M. Bétermier, O. Arnaiz, 2024, Cell reports.

Crystallization and preliminary X-ray diffraction data of the complex between human centrin 2 and a peptide from the protein XPC.

E. Stura, S. Miron, C. Craescu, 2006, Acta crystallographica. Section F, Structural biology and crystallization communications.

HLTF disrupts Cas9-DNA post-cleavage complexes to allow DNA break processing

M. Jinek, J. Charbonnier, E. Cannavó, 2024, Nature communications.