Ying Tang

发表

Monoclonal Antibody Clearance

Ying Tang, A. Datta-Mannan, D. Witcher, 2007, Journal of Biological Chemistry.

The interplay of non-specific binding, target-mediated clearance and FcRn interactions on the pharmacokinetics of humanized antibodies

Ying Tang, A. Datta-Mannan, D. Witcher, 2015, mAbs.

Ultra-potent antibodies against respiratory syncytial virus: effects of binding kinetics and binding valence on viral neutralization.

Ying Tang, Herren Wu, W. Huse, 2005, Journal of molecular biology.

Generation and characterization of ixekizumab, a humanized monoclonal antibody that neutralizes interleukin-17A

K. Kikly, Ying Tang, V. Wroblewski, 2016, Journal of inflammation research.

Cancer Therapy: Preclinical LY2875358, a Neutralizing and Internalizing Anti-MET Bivalent Antibody, Inhibits HGF-Dependent and HGF-Independent MET Activation and Tumor Growth

Ying Tang, J. Manro, K. Credille, 2014 .

Humanized IgG1 Variants with Differential Binding Properties to the Neonatal Fc Receptor: Relationship to Pharmacokinetics in Mice and Primates

A. Datta-Mannan, D. Witcher, Ying Tang, 2007, Drug Metabolism and Disposition.

Cancer Therapy : Preclinical LY 2875358 , a Neutralizing and Internalizing Anti-MET Bivalent Antibody , Inhibits HGF-Dependent and HGF-Independent MET Activation and Tumor Growth

Ying Tang, J. Manro, K. Credille, 2014 .

Use of a Peptide Mimotope to Guide the Humanization of MRK-16, an Anti-P-glycoprotein Monoclonal Antibody*

W. Huse, Ying Tang, J. Watkins, 1999, The Journal of Biological Chemistry.

LY2875358, a Neutralizing and Internalizing Anti-MET Bivalent Antibody, Inhibits HGF-Dependent and HGF-Independent MET Activation and Tumor Growth

Ying Tang, J. Manro, K. Credille, 2014, Clinical Cancer Research.

A Plaque-Specific Antibody Clears Existing β-amyloid Plaques in Alzheimer's Disease Mice

W. H. Jordan, M. Hutton, P. Mcdonnell, 2012, Neuron.

Balancing charge in the complementarity-determining regions of humanized mAbs without affecting pI reduces non-specific binding and improves the pharmacokinetics

A. Datta-Mannan, D. Witcher, Ying Tang, 2015, mAbs.

COMBINATION THERAPY WITH A PLAQUE-SPECIFIC ABETA ANTIBODY AND BACE INHIBITOR RESULTS IN DRAMATIC PLAQUE LOWERING IN AGED PDAPP TRANSGENIC MICE

R. Demattos, C. Delong, P. May, 2014, Alzheimer's & Dementia.

Abstract 2734: c-Met antibody LY2875358 (LA480) shows differential antitumor effects in non-small cell lung cancer

Ying Tang, J. Manro, J. Lu, 2012 .

Abstract 873: A novel MET-EGFR bispecific antibody LY3164530 shows advantage over combining MET and EGFR antibodies in tumor inhibition and overcome resistance

Ying Tang, J. Lu, Wei Zeng, 2016 .

Generation and characterization of ixekizumab, a humanized monoclonal antibody that neutralizes interleukin-17A

K. Kikly, Ying Tang, V. Wroblewski, 2016, Journal of inflammation research.