D. Roopenian

D. Roopenian, R. Levy, A. Shatry, 2007, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Shaping the repertoire of cytotoxic T-lymphocyte responses: explanation for the immunodominance effect whereby cytotoxic T lymphocytes specific for immunodominant antigens prevent recognition of nondominant antigens.

C. Perreault, D. Roopenian, G. Christianson, 1999, Blood.

Naturally variant autosomal and sex-linked loci determine the severity of iron overload in β2-microglobulin-deficient mice

W. Sly, B. Bacon, R. Britton, 2001, Proceedings of the National Academy of Sciences of the United States of America.

A new MHC locus that influences class I peptide presentation.

R. Hammer, S. Summerfield, C. Slaughter, 1997, Immunity.

Cdcs1 a major colitis susceptibility locus in mice; Subcongenic analysis reveals genetic complexity

J. Affourtit, J. Sundberg, A. Bleich, 2010, Inflammatory bowel diseases.

Blocking FcRn in humans reduces circulating IgG levels and inhibits IgG immune complex–mediated immune responses

L. Pearce, A. Bitonti, J. Andersen, 2019, Science Advances.

All Others Histocompatibility Antigen Dominates Over Transplantation Antigens In Vivo : The H 60 Response to Mouse Non-MHC Quantitative Analysis of the Immune

N. Shastri, S. Malarkannan, E. Choi, 2001 .

Expansion of the CD4−, CD8− γδ T cell subset in the spleens of mice during non‐lethal blood‐stage malaria

D. Roopenian, H. C. van der Heyde, M. Elloso, 1993 .

Response against single minor histocompatibility antigens. I. Functional and immunogenetic analysis of cloned cytolytic T cells.

C. Orosz, F. Bach, D. Roopenian, 1983, Journal of immunology.

Encoded by the Classical H7 Minor an Immunodominant Peptide (B6dom1) Biochemical and Immunogenetic Analysis of

C. Perreault, D. Roopenian, J. Wettstein, 2013 .

Responses against antigens encoded by theH-3 histocompatibility locus: Antigens stimulating class I MHC- and class II MHC-restricted T cells are encoded by separate genes

D. Roopenian, A. P. Davis, 2006, Immunogenetics.

Complexity at the mouse minor histocompatibility locusH-4

D. Roopenian, A. P. Davis, 2004, Immunogenetics.

The H4b Minor Histocompatibility Antigen Is Caused by a Combination of Genetically Determined and Posttranslational Modifications1

D. Roopenian, Y. Yoshimura, S. Joyce, 2003, The Journal of Immunology.

Immunodominance of H60 is caused by an abnormally high precursor T cell pool directed against its unique minor histocompatibility antigen peptide.

Eun Young Choi, Sebastian Joyce, E. Choi, 2002, Immunity.

Biochemical and immunogenetic analysis of an immunodominant peptide (B6dom1) encoded by the classical H7 minor histocompatibility locus.

C. Perreault, D. Roopenian, P. Wettstein, 1999, Journal of immunology.

A molecular basis for how a single TCR interfaces multiple ligands.

M. Brehm, D. Roopenian, S. Tevethia, 1998, Journal of immunology.

Interfaces Multiple Ligands A Molecular Basis for How a Single TCR Roopenian and

M. Brehm, D. Roopenian, S. Tevethia, 1998 .

A single nucleotide polymorphism in the Emp3 gene defines the H4 minor histocompatibility antigen

S. Malarkannan, E. Choi, D. Roopenian, 2003, Immunogenetics.

A genetic linkage map of mouse chromosome 2 extending from thrombospondin to paired box gene 1, including the H3 minor histocompatibility complex.

B. Taylor, D. Roopenian, A. Zuberi, 1996, Genomics.

Generation of helper cell-independent cytotoxic T lymphocytes is dependent upon L3T4+ helper T cells.

P. Anderson, D. Roopenian, 1988, Journal of immunology.

NF-κB Signaling Regulates Functional Expression of the MHC Class I-Related Neonatal Fc Receptor for IgG via Intronic Binding Sequences1

D. Roopenian, Xiaoping Zhu, G. Christianson, 2007, The Journal of Immunology.

Inhibition of Glycolysis Reduces Disease Severity in an Autoimmune Model of Rheumatoid Arthritis

L. Morel, D. Roopenian, Seung-Chul Choi, 2018, Front. Immunol..

Augmented glucose dependency of autoreactive B cells provides a treatment target for lupus

P. Lipsky, Chih-Hao Chang, A. Grammer, 2022, bioRxiv.

Adhesion Molecule Deficiencies Increase Porphyromonas gingivalis-Induced Alveolar Bone Loss in Mice

D. Roopenian, M. Dixon, P. Baker, 2000, Infection and Immunity.

Adhesion Molecule Deﬁciencies Increase Porphyromonas gingivalis Induced Alveolar Bone Loss in Mice

D. Roopenian, P. Baker, L. Dufour, 2000 .

The MHC Class I-Like IgG Receptor Controls Perinatal IgG Transport, IgG Homeostasis, and Fate of IgG-Fc-Coupled Drugs1

E. Choi, S. Akilesh, C. Anderson, 2003, The Journal of Immunology.

FcRn is a CD32a coreceptor that determines susceptibility to IgG immune complex–driven autoimmunity

E. Fiebiger, J. Andersen, J. Glickman, 2020, The Journal of experimental medicine.

Serum antibody response to oral infection precedes but does not prevent Porphyromonas gingivalis-induced alveolar bone loss in mice.

D. Roopenian, P. Baker, R. T. Evans, 1999, Oral microbiology and immunology.

Duration of Alloantigen Presentation and Avidity of T Cell Antigen Recognition Correlate with Immunodominance of CTL Response to Minor Histocompatibility Antigens1

D. Roopenian, Y. Yoshimura, S. Joyce, 2004, The Journal of Immunology.

NOTCH is part of the transcriptional network regulating cell growth and survival in mouse plasmacytomas.

D. Roopenian, Hongsheng Wang, H. Morse, 2008, Cancer research.

Phorbol myristate acetate and in vitro T lymphocyte function. II. Influence of PMA and supernatants from PMA-treated P388D1 cells on the proliferation of cloned T cells.

C. Orosz, F. Bach, D. Roopenian, 1983, Journal of Immunology.

In vivo role of ER-associated peptidase activity in tailoring peptides for presentation by MHC class Ia and class Ib molecules

Vrajesh V. Parekh, D. Roopenian, L. Van Kaer, 2006, The Journal of experimental medicine.

Seven naturally variant loci serve as genetic modifiers of Lamc2jeb induced non-Herlitz junctional Epidermolysis Bullosa in mice

V. Philip, D. Roopenian, T. Sproule, 2023, bioRxiv.

Accelerated wound healing of alkali-burned corneas in MRL mice is associated with a reduced inflammatory signature.

D. Roopenian, L. Shultz, L. Burzenski, 2005, Investigative ophthalmology & visual science.

How H13 Histocompatibility Peptides Differing by a Single Methyl Group and Lacking Conventional MHC Binding Anchor Motifs Determine Self-Nonself Discrimination1

H. Grey, N. Shastri, S. Almo, 2002, The Journal of Immunology.

Discrimination Motifs Determine Self-Nonself Lacking Conventional MHC Binding Anchor Differing by a Single Methyl Group and How H13 Histocompatibility Peptides

H. Grey, N. Shastri, S. Almo, 2001 .

Genetic modification of hearing in tubby mice: evidence for the existence of a major gene (moth1) which protects tubby mice from hearing loss.

J. Naggert, P. Rosenstiel, M. North, 1999, Human molecular genetics.

A single-amino-acid variant of the H60 CD8 epitope generates specific immunity with diverse TCR recruitment

Jun Chang, E. Choi, D. Roopenian, 2012, Molecules and cells.

Human neonatal Fc receptor mediates transport of IgG into luminal secretions for delivery of antigens to mucosal dendritic cells.

D. Roopenian, W. Lencer, R. Blumberg, 2004, Immunity.

Additional mapping of mouse chromosome 2 genes

D. Roopenian, R. Graff, M. Kurtz, 2004, Immunogenetics.

A new minor histocompatibility locus linked to H-3.

D. Roopenian, R. E. Click, D. Schneider, 1981, Journal of immunology.

CD8+ T regulatory cells express the Ly49 Class I MHC receptor and are defective in autoimmune prone B6-Yaa mice

D. Roopenian, T. Sproule, H. Cantor, 2011, Proceedings of the National Academy of Sciences.

Features of Plasma Cell-Related Neoplasms in Mice

Chen-feng Qi, M. Potter, A. Kovalchuk, 2010 .

Abrogated AID Function Prolongs Survival and Diminishes Renal Pathology in the BXSB Mouse Model of Systemic Lupus Erythematosus

D. Roopenian, T. Sproule, T. LeRoith, 2020, The Journal of Immunology.

The Major Histocompatibility Complex–related Fc Receptor for IgG (FcRn) Binds Albumin and Prolongs Its Lifespan

D. Pearl, C. Chaudhury, J. M. Robinson, 2003, The Journal of experimental medicine.

Clinical Ramifications of the MHC Family Fc Receptor FcRn

D. Roopenian, V. Z. Sun, Victor Z. Sun, 2010, Journal of Clinical Immunology.

Lessons from H3, a model autosomal mouse minor histocompatibility locus.

D. Roopenian, 2000 .

Lupus nephritis in the absence of renal major histocompatibility complex class I and class II molecules.

D. Roopenian, A. Jevnikar, Z. Zhang, 1996, Journal of the American Society of Nephrology : JASN.

Expression of neonatal Fc receptor in the eye.

M. Fruttiger, D. Roopenian, G. Christianson, 2014, Investigative ophthalmology & visual science.

Genetic influence on immune phenotype revealed strain-specific variations in peripheral blood lineages.

S. Tsaih, B. Paigen, D. Roopenian, 2008, Physiological genomics.

Efficient Mucosal Delivery of Vaccine Using the FcRn-Mediated IgG Transfer Pathway

D. Roopenian, Xiaoping Zhu, R. Zeng, 2011, Nature Biotechnology.

The Immunologic Functions of the Neonatal Fc Receptor for IgG

E. Fiebiger, S. Qiao, D. Roopenian, 2012, Journal of Clinical Immunology.

Mitochondrially-Encoded Minor Histocompatibility Antigens

D. Roopenian, 1999 .

Transcriptome analysis reveals organ-specific effects of 2-deoxyglucose treatment in healthy mice

G. Carter, C. Kaczorowski, D. Roopenian, 2024, PloS one.

The Cinderella effect: searching for the best fit between mouse models and human diseases.

E. Liu, J. Sundberg, P. Schofield, 2013, The Journal of investigative dermatology.

Mechanisms of Cross-Presentation in Graft-Vs-Host Disease.

D. Roopenian, Ning Li, Hongmei Li, 2009 .

T cell knockout mice have diminished alveolar bone loss after oral infection with Porphyromonas gingivalis.

D. Roopenian, P. Baker, L. Howe, 2002, FEMS immunology and medical microbiology.

Resolution of blood-stage malarial infections in CD8+ cell-deficient beta 2-m0/0 mice.

D. Roopenian, H. C. van der Heyde, D. D. Manning, 1993, Journal of immunology.

An intact C-terminal end of albumin is required for its long half-life in humans

J. Andersen, B. Dalhus, D. Roopenian, 2020, Communications Biology.

Anticorps anti-fcrn à maturation d'affinité humanisés

S. D. Jones, D. Roopenian, R. Blumberg, 2016 .

Animal models for evaluation of albumin-based therapeutics

J. Andersen, D. Roopenian, I. Sandlie, 2018 .

Monoclonal antibodies directed against human FcRn and their applications

G. Proetzel, S. Akilesh, D. Roopenian, 2012, mAbs.

Transfer of IgG in the female genital tract by the FcRn confers protective immunity to vaginal infection (59.3)

D. Roopenian, Xiaoping Zhu, W. Tuo, 2011, The Journal of Immunology.

Molecular Identification of Collagen 17a1 as a Major Genetic Modifier of Laminin Gamma 2 Mutation-Induced Junctional Epidermolysis Bullosa in Mice

J. Sundberg, V. Philip, J. Bubier, 2014, PLoS genetics.

A direct method to determine the strength of the dermal–epidermal junction in a mouse model for epidermolysis bullosa

D. Roopenian, T. Sproule, J. Sundberg, 2012, Experimental dermatology.

Responses against single minor histocompatibility antigens. II. Analysis of cloned helper T cells.

C. Orosz, F. Bach, D. Roopenian, 1984, Journal of immunology.

Transcriptome Analysis Reveals Organ-Specific Effects of 2-Deoxyglucose Treatment in Healthy Mice

G. Carter, C. Kaczorowski, D. Roopenian, 2023, bioRxiv.

Genetically Engineered Humanized Mouse Models for Preclinical Antibody Studies

G. Proetzel, M. Wiles, D. Roopenian, 2014, BioDrugs.

Increased expression of Cxcr3 and its ligands, Cxcl9, and Cxcl10, during the development of alopecia areata in the mouse

J. Sundberg, H. Everts, D. Roopenian, 2012, The Journal of investigative dermatology.

Glucose oxidation-dependent survival of activated B cells provides a putative novel therapeutic target for lupus treatment

P. Lipsky, A. Grammer, G. Stafford, 2023, iScience.

A new immunosuppressive mechanism for cyclosporin-A demonstrated with cloned T-lymphocytes.

C. Orosz, F. Bach, D. Roopenian, 1983 .

Pooling and PCR as a method to combat low frequency gene targeting in mouse embryonic stem cells

J. Graber, D. Roopenian, C. Lerner, 2006, Cytotechnology.

ADOPTIVE IMMUNITY IN IMMUNE‐DEFICIENT scid/scid MICE: I. Differential Requirements of Naive and Primed Lymphocytes for CD4+ T Cells During Rejection of Minor Histocompatibility Antigen‐Disparate Skin Grafts

P. Anderson, D. Roopenian, 1988, Transplantation.

Transporters from H-2b, H-2d, H-2s, H-2k, and H-2g7 (NOD/Lt) haplotype translocate similar sets of peptides.

T. Schumacher, H. Ploegh, D. Roopenian, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Human FcRn Transgenic Mice for Pharmacokinetic Evaluation of Therapeutic Antibodies.

G. Proetzel, D. Roopenian, T. Sproule, 2016, Methods in molecular biology.

Foxn1 Regulates Lineage Progression in Cortical and Medullary Thymic Epithelial Cells But Is Dispensable for Medullary Sublineage Divergence

D. Roopenian, Andrew J. H. Smith, N. Bredenkamp, 2011, PLoS genetics.

Quantitative Gene Expression Profiling Implicates Genes for Susceptibility and Resistance to Alveolar Bone Loss

D. Roopenian, D. Shaffer, Aaron C. Brown, 2004, Infection and Immunity.

Dystonin modifiers of junctional epidermolysis bullosa and models of epidermolysis bullosa simplex without dystonia musculorum

D. Roopenian, T. Sproule, B. Low, 2023, PloS one.

Clinical chemistry of human FcRn transgenic mice

M. Angelis, E. Wolf, G. Proetzel, 2011, Mammalian Genome.

Functional analysis of Collagen 17a1: A genetic modifier of junctional epidermolysis bullosa in mice

D. Reyon, D. Roopenian, T. Sproule, 2023, PloS one.

A mouse model of generalized non-Herlitz junctional epidermolysis bullosa.

J. Sundberg, J. Bubier, D. Roopenian, 2010, The Journal of investigative dermatology.

Human antibodies induce arthritis in mice deficient in the low-affinity inhibitory IgG receptor FcγRIIB

D. Roopenian, T. Sproule, K. Konstantinov, 2006, The Journal of experimental medicine.

Human FcRn Transgenic Mice for Pharmacokinetic Evaluation of Therapeutic Antibodies.

G. Proetzel, D. Roopenian, T. Sproule, 2016, Methods in molecular biology.

A single-amino-acid variant of the H60 CD8 epitope generates specific immunity with diverse TCR recruitment

Jun Chang, E. Choi, D. Roopenian, 2012, Molecules and cells.

MHC Class I Family Proteins Retard Systemic Lupus Erythematosus Autoimmunity and B Cell Lymphomagenesis

J. Bubier, D. Roopenian, T. Sproule, 2011, Journal of Immunology.

AI-03 Efficacy and safety of intermittent 2-deoxyglucose therapy in mouse models of lupus

L. Morel, D. Roopenian, T. Sproule, 2018, Adaptive Immunity.

This information is current as Dendritic Cells to Pancreatic Lymph Nodes Diabetes through Tolerogenic Recruitment of Activated NKT Cells Inhibit Autoimmune

G. Besra, C. Choisy-Rossi, D. Roopenian, 2005 .

Novel HY peptide antigens presented by HLA-B27.

R. Hammer, C. Slaughter, S. Gaskell, 1999, Journal of immunology.

B Cell IgD Deletion Prevents Alveolar Bone Loss Following Murine Oral Infection

D. Roopenian, M. Tiffany, P. Baker, 2009, Interdisciplinary perspectives on infectious diseases.

Antigen-Specific Allograft Tolerance by Molecular Mechanisms of Induction of

C. Addey, Daniel W. Stuckey, J. Bubier, 2011 .