O. Avrutina

发表

Knottin cyclization: impact on structure and dynamics

L. Chiche, H. Kolmar, A. Heitz, 2008, BMC Structural Biology.

Cube-octameric silsesquioxane-mediated cargo peptide delivery into living cancer cells.

M. C. Cardoso, R. Stark, H. Kolmar, 2013, Organic and biomolecular chemistry.

Nanoscale Biodegradable Organic-Inorganic Hybrids for Efficient Cell Penetration and Drug Delivery.

H. Kolmar, O. Avrutina, S. Hörner, 2016, Angewandte Chemie.

Light-Controlled Chemoenzymatic Immobilization of Proteins towards Engineering of Bioactive Papers.

T. Meckel, H. Kolmar, O. Avrutina, 2019, Chemistry.

Protein Production in Yarrowia lipolytica Via Fusion to the Secreted Lipase Lip2p

H. U. Göringer, Michael Brecht, H. Kolmar, 2013, Molecular Biotechnology.

Efficient Site‐Specific Antibody–Drug Conjugation by Engineering a Nature‐Derived Recognition Tag for Microbial Transglutaminase

H. Kolmar, O. Avrutina, H. Fuchsbauer, 2019, Chembiochem : a European journal of chemical biology.

Effective PHIP labeling of bioactive peptides boosts the intensity of the NMR signal.

H. Kolmar, O. Avrutina, G. Buntkowsky, 2014, Angewandte Chemie.

PHIP-label: parahydrogen-induced polarization in propargylglycine-containing synthetic oligopeptides.

H. Kolmar, O. Avrutina, G. Buntkowsky, 2013, Chemical communications.

Engineering a Constrained Peptidic Scaffold towards Potent and Selective Furin Inhibitors

H. Kolmar, O. Avrutina, M. Than, 2015, Chembiochem : a European journal of chemical biology.

Application of copper(I) catalyzed azide-alkyne [3+2] cycloaddition to the synthesis of template-assembled multivalent peptide conjugates.

H. Kolmar, O. Avrutina, U. Diederichsen, 2009, Organic & biomolecular chemistry.

Synthetic Cystine-Knot Miniproteins - Valuable Scaffolds for Polypeptide Engineering.

O. Avrutina, 2016, Advances in experimental medicine and biology.

Cystine‐knot peptides targeting cancer‐relevant human cytotoxic T lymphocyte‐associated antigen 4 (CTLA‐4)

U. Şahin, H. Kolmar, O. Avrutina, 2015, Journal of peptide science : an official publication of the European Peptide Society.

Fragmentation Follows Structure: Top-Down Mass Spectrometry Elucidates the Topology of Engineered Cystine-Knot Miniproteins

H. Kolmar, O. Avrutina, Sebastian Fabritz, 2014, PloS one.

"Triazole bridge": disulfide-bond replacement by ruthenium-catalyzed formation of 1,5-disubstituted 1,2,3-triazoles.

H. Kolmar, O. Avrutina, G. Buntkowsky, 2011, Angewandte Chemie.

Braces for the peptide backbone: insights into structure-activity relationships of protease inhibitor mimics with locked amide conformations.

D. Heinz, H. Kolmar, O. Avrutina, 2012, Angewandte Chemie.

Dextramabs: A Novel Format of Antibody‐Drug Conjugates Featuring a Multivalent Polysaccharide Scaffold

H. Kolmar, O. Avrutina, Desislava Yanakieva, 2019, ChemistryOpen.

Head‐to‐Tail Cyclized Cystine‐Knot Peptides by a Combined Recombinant and Chemical Route of Synthesis

A. Wentzel, H. Kolmar, O. Avrutina, 2008, Chembiochem : a European journal of chemical biology.

TRAIL‐Inspired Multivalent Dextran Conjugates Efficiently Induce Apoptosis upon DR5 Receptor Clustering

H. Kolmar, O. Avrutina, Desislava Yanakieva, 2019, Chembiochem : a European journal of chemical biology.

Oxidative Folding of Peptides with Cystine‐Knot Architectures: Kinetic Studies and Optimization of Folding Conditions

H. Kolmar, O. Avrutina, Sebastian Fabritz, 2013, Chembiochem : a European journal of chemical biology.

Combinatorial Optimization of Cystine-Knot Peptides towards High-Affinity Inhibitors of Human Matriptase-1

A. Christmann, H. Kolmar, O. Avrutina, 2013, PloS one.

Engineered cystine knot miniproteins as potent inhibitors of human mast cell tryptase beta.

H. Kolmar, O. Avrutina, U. Diederichsen, 2010, Journal of molecular biology.

Trypsin inhibition by macrocyclic and open-chain variants of the squash inhibitor MCoTI-II

H. Kolmar, O. Avrutina, U. Diederichsen, 2005, Biological chemistry.

Fmoc-Assisted Synthesis of a 29-Residue Cystine-Knot Trypsin Inhibitor Containing a Guaninyl Amino Acid at the P1-Position

H. Kolmar, O. Avrutina, U. Diederichsen, 2004 .

Synthetic Integrin-Targeting Dextran-Fc Hybrids Efficiently Inhibit Tumor Proliferation In Vitro

H. Kolmar, O. Avrutina, Hendrik Schneider, 2021, Frontiers in Chemistry.

An Apoptosis-Inducing Peptidic Heptad That Efficiently Clusters Death Receptor 5.

H. Kolmar, O. Avrutina, Stefan Zielonka, 2016, Angewandte Chemie.

Multivalent dextran hybrids for efficient cytosolic delivery of biomolecular cargoes

T. Meckel, H. Kolmar, O. Avrutina, 2021, Journal of peptide science : an official publication of the European Peptide Society.

Microbial transglutaminase for biotechnological and biomedical engineering

Lukas Deweid, Olga Avrutina, Harald Kolmar, 2018, Biological chemistry.

From pico to nano: biofunctionalization of cube-octameric silsesquioxanes by peptides and miniproteins.

H. Kolmar, O. Avrutina, C. Dietz, 2012, Organic & biomolecular chemistry.

Sustainable Peptide Synthesis Enabled by a Transient Protecting Group

H. Kolmar, O. Avrutina, R. Meusinger, 2020, Angewandte Chemie.

Between two worlds: a comparative study on in vitro and in silico inhibition of trypsin and matriptase by redox-stable SFTI-1 variants at near physiological pH.

H. Kolmar, O. Avrutina, M. Empting, 2012, Organic & biomolecular chemistry.

Enhancing the Pharmacokinetics and Antitumor Activity of an α-Amanitin-Based Small-Molecule Drug Conjugate via Conjugation with an Fc Domain.

H. Kolmar, O. Avrutina, A. Pahl, 2021, Journal of medicinal chemistry.

Functional paper-based materials for diagnostics

H. Kolmar, O. Avrutina, M. Biesalski, 2021, ChemTexts.

Towards click bioconjugations on cube-octameric silsesquioxane scaffolds.

W. Fessner, J. J. Schneider, H. Kolmar, 2010, Organic & biomolecular chemistry.

A sensitive method for rapid detection of alkyl halides and dehalogenase activity using a multistep enzyme assay

H. Kolmar, O. Avrutina, Sebastian Fabritz, 2012, AMB Express.

Chemical Synthesis, Backbone Cyclization and Oxidative Folding of Cystine-knot Peptides — Promising Scaffolds for Applications in Drug Design

H. Kolmar, O. Avrutina, Daichi Nasu, 2012, Molecules.

A chemoenzymatic approach to protein immobilization onto crystalline cellulose nanoscaffolds.

Kai Zhang, Hannes Orelma, Olga Avrutina, 2014, Angewandte Chemie.

Locked by Design: A Conformationally Constrained Transglutaminase Tag Enables Efficient Site-Specific Conjugation.

Jan Beck, Stefan Schmelz, Andrea Scrima, 2015, Angewandte Chemie.

Potent inhibitors of human matriptase‐1 based on the scaffold of sunflower trypsin inhibitor

H. Kolmar, O. Avrutina, M. Empting, 2014, Journal of peptide science : an official publication of the European Peptide Society.

Discovery of the first small-molecule CsrA-RNA interaction inhibitors using biophysical screening technologies.

R. Hartmann, R. Müller, O. Avrutina, 2016, Future medicinal chemistry.

Recent progress in transglutaminase-mediated assembly of antibody-drug conjugates.

H. Kolmar, O. Avrutina, Hendrik Schneider, 2020, Analytical biochemistry.

Covalent Attachment of Enzymes to Paper Fibers for Paper-Based Analytical Devices

Olga Avrutina, Harald Kolmar, Alexander Böhm, 2018, Front. Chem..

Self-Assembled Hybrid Aptamer-Fc Conjugates for Targeted Delivery: A Modular Chemoenzymatic Approach.

H. Kolmar, O. Avrutina, U. Diederichsen, 2015, ACS chemical biology.

Ultrafast Single-Scan 2D NMR Spectroscopic Detection of a PHIP-Hyperpolarized Protease Inhibitor.

H. Kolmar, O. Avrutina, G. Buntkowsky, 2019, Chemistry.

Tailoring Activity and Selectivity of Microbial Transglutaminase.

H. Kolmar, O. Avrutina, Lukas Deweid, 2019, Methods in molecular biology.

Correction: Combination of inverse electron-demand Diels-Alder reaction with highly efficient oxime ligation expands the toolbox of site-selective peptide conjugations.

H. Kolmar, O. Avrutina, S. Hörner, 2015, Chemical communications.

Directed Evolution of a Bond-Forming Enzyme: Ultrahigh-Throughput Screening of Microbial Transglutaminase Using Yeast Surface Display.

A. Christmann, H. Kolmar, O. Avrutina, 2018, Chemistry.

Parahydrogen-induced polarization allows 2000-fold signal enhancement in biologically active derivatives of the peptide-based drug octreotide

H. Kolmar, O. Avrutina, G. Buntkowsky, 2023, Scientific reports.

Combinatorial tuning of peptidic drug candidates: high-affinity matriptase inhibitors through incremental structure-guided optimization.

H. Kolmar, O. Avrutina, M. Empting, 2013, Organic & biomolecular chemistry.