S. Yao

发表

Microarray: a versatile platform for high-throughput functional proteomics.

Mahesh Uttamchandani, Shao Q Yao, Yi Hu, 2006, Combinatorial chemistry & high throughput screening.

Protein and small molecule microarrays: powerful tools for high-throughput proteomics.

Jun Wang, Mahesh Uttamchandani, Shao Q Yao, 2006, Molecular bioSystems.

Small Molecule Microarrays

M. Uttamchandani, S. Yao, 2017, Methods in Molecular Biology.

Tetrazole Photoclick Chemistry: Reinvestigating Its Suitability as a Bioorthogonal Reaction and Potential Applications.

S. Yao, Jun‐Seok Lee, Zhengqiu Li, 2016, Angewandte Chemie.

Recent advances in peptide-based microarray technologies.

S. Yao, Xuan Huang, Resmi C. Panicker, 2004, Combinatorial chemistry & high throughput screening.

Rapid affinity-based fingerprinting of 14-3-3 isoforms using a combinatorial peptide microarray.

Y. Liou, M. Uttamchandani, S. Yao, 2008, Angewandte Chemie.

Shape-Dependent Two-Photon Photoluminescence of Single Gold Nanoparticles

Na Zhou, Qing-Hua Xu, Zhenping Guan, 2014 .

Bypassing Endocytosis: Direct Cytosolic Delivery of Proteins.

S. Yao, S. S. Liew, Lin Li, 2018, Journal of the American Chemical Society.

Multicolor, one- and two-photon imaging of enzymatic activities in live cells with fluorescently Quenched Activity-Based Probes (qABPs).

Pengyu Yang, M. Uttamchandani, S. Yao, 2011, Journal of the American Chemical Society.

"Click" synthesis of small molecule-peptide conjugates for organelle-specific delivery and inhibition of lysosomal cysteine proteases.

S. Yao, Haibin Shi, Mingyu Hu, 2010, Chemical communications.

Reaction-Based Off-On Near-infrared Fluorescent Probe for Imaging Alkaline Phosphatase Activity in Living Cells and Mice.

S. Yao, Hongyan Sun, Liyi Zhou, 2017, ACS applied materials & interfaces.

Expanded utility of the native chemical ligation reaction.

S. Yao, D. Yeo, R. Srinivasan, 2004, Chemistry.

Current Chemical Biology Tools for Studying Protein Phosphorylation and Dephosphorylation

S. Yao, Candy H. S. Lu, Kai Liu, 2012 .

Activity-based proteome profiling of hepatoma cells during hepatitis C virus replication using protease substrate probes.

S. Yao, J. Pezacki, S. Bélanger, 2010, Journal of proteome research.

Rational Design of Nanocarriers for Intracellular Protein Delivery

S. Yao, Lin Li, Cheng-wu Zhang, 2019, Advanced materials.

Solid-phase synthesis of peptide vinyl sulfones as potential inhibitors and activity-based probes of cysteine proteases.

S. Yao, Grace Y. J. Chen, Gang Wang, 2003, Organic letters.

Competition-Based Universal Photonic Crystal Biosensors by Using Antibody-Antigen Interaction.

J. Qin, S. Yao, Lixin Cao, 2019, Journal of the American Chemical Society.

A self-immobilizing and fluorogenic unnatural amino acid that mimics phosphotyrosine.

S. Yao, Lin Li, Jingyan Ge, 2011, Chemical communications.

Chemical modification and organelle-specific localization of orlistat-like natural-product-based probes.

Pengyu Yang, S. Yao, Chong-Jing Zhang, 2011, Chemistry, an Asian journal.

Activity-based fingerprinting and inhibitor discovery of cysteine proteases in a microarray.

M. Uttamchandani, S. Yao, Resmi C. Panicker, 2007, Chemical communications.

Activity‐based profiling of the proteasome pathway during hepatitis C virus infection

D. Figeys, Zhibin Ning, S. Yao, 2015, Proteomics.

Rapid synthesis, screening, and identification of xanthone- and xanthene-based fluorophores using click chemistry.

S. Yao, Junqi Li, Mingyu Hu, 2009, Organic letters.

Smart Design of Nanomaterials for Mitochondria-Targeted Nanotherapeutics.

S. Yao, S. S. Liew, Xiaofei Qin, 2020, Angewandte Chemie.

Cell-Permeant Bioadaptors for Cytosolic Delivery of Native Antibodies: A “Mix-and-Go” Approach

S. Yao, S. S. Liew, Lin Li, 2020, ACS central science.

Nanoquencher-Based Selective Imaging of Protein Glutathionylation in Live Mammalian Cells

S. Yao, Lin Li, Changmin Yu, 2018, Angewandte Chemie.

Nanoquencher-Based Selective Imaging of Protein Glutathionylation in Live Mammalian Cells.

S. Yao, Lin Li, Changmin Yu, 2018, Angewandte Chemie.

Two-Photon Enzymatic Probes Visualizing Sub-cellular/Deep-brain Caspase Activities in Neurodegenerative Models

K. Lim, S. Yao, Qinghua Xu, 2016, Scientific Reports.

Live-Cell Imaging of Survivin mRNA by Using a Dual-Color Surface-Cross-Linked Nanoquencher.

S. Yao, Changyu Zhang, Sing Yee Ong, 2021, Analytical chemistry.

Light-Triggered PEGylation/dePEGylation of the Nanocarriers for Enhanced Tumor Penetration.

Y. Hu, Z. Chai, S. Yao, 2019, Nano letters.

Rational Design of Two-photon Fluorogenic Probe for Visualizing Monoamine Oxidase A Activity in Human Glioma Tissues.

S. Yao, Cheng-wu Zhang, Lin Li, 2020, Angewandte Chemie.

Rational Design of a Two‐Photon Fluorogenic Probe for Visualizing Monoamine Oxidase A Activity in Human Glioma Tissues

S. Yao, Cheng-wu Zhang, Lin Li, 2020, Angewandte Chemie.

A minimalist ﬂ uorescent probe for di ﬀ erentiating Cys, Hcy and GSH in live cells † Royal

Lin Li, Zhengtao Xu, S. Yao, 2015 .

Recent advances in construction of small molecule-based fluorophore-drug conjugates

S. Yao, Linghui Qian, Shubo Du, 2020, Journal of pharmaceutical analysis.

Intracellular Delivery of Native Proteins Facilitated by Cell-Penetrating Poly(disulfide)s.

S. Yao, Linghui Qian, Lin Li, 2018, Angewandte Chemie.

Rapid synthesis of Abelson tyrosine kinase inhibitors using click chemistry.

Karunakaran A Kalesh, S. Yao, Kai Liu, 2009, Organic & biomolecular chemistry.

High-throughput synthesis of azide libraries suitable for direct "click" chemistry and in situ screening.

Karunakaran A Kalesh, Pengyu Yang, S. Yao, 2009, Organic & biomolecular chemistry.

"Click" synthesis of small-molecule inhibitors targeting caspases.

Pengyu Yang, S. Yao, R. Srinivasan, 2008, Organic & biomolecular chemistry.

Small molecule microarray-facilitated screening of affinity-based probes (AfBPs) for gamma-secretase.

S. Yao, Haibin Shi, Kai Liu, 2009, Chemical communications.

Iron modulates the activity of monoamine oxidase B in SH-SY5Y cells

Y. Hu, Z. Chai, S. Yao, 2017, BioMetals.

A Small-Molecule Probe for Selective Profiling and Imaging of Monoamine Oxidase B Activities in Models of Parkinson's Disease.

K. Lim, S. Yao, Jun‐Seok Lee, 2015, Angewandte Chemie.

Visualization of monoamine oxidases in living cells using "Turn-ON" fluorescence resonance energy transfer probes.

Yuguo Zheng, S. Yao, Linghui Qian, 2014, The Analyst.

AMPK mediates a pro‐survival autophagy downstream of PARP‐1 activation in response to DNA alkylating agents

S. Yao, Youtong Wu, Qing Huang, 2013, FEBS letters.

Puromycin Analogues Capable of Multiplexed Imaging and Profiling of Protein Synthesis and Dynamics in Live Cells and Neurons.

K. Lim, S. Yao, T. Wohland, 2016, Angewandte Chemie.

Activity‐Based Protein Profiling: New Developments and Directions in Functional Proteomics

M. Uttamchandani, S. Yao, Hongyan Sun, 2008, Chembiochem : a European journal of chemical biology.

Developing photoactive affinity probes for proteomic profiling: hydroxamate-based probes for metalloproteases.

S. Chattopadhaya, S. Yao, Xuan Huang, 2004, Journal of the American Chemical Society.

Live-cell imaging and profiling of c-Jun N-terminal kinases using covalent inhibitor-derived probes.

S. Yao, Jun‐Seok Lee, Linghui Qian, 2019, Chemical Communications.

Microarray-guided discovery of two-photon (2P) small molecule probes for live-cell imaging of cysteinyl cathepsin activities.

M. Uttamchandani, S. Yao, Lin Li, 2012, Chemical communications.

Methods of using click chemistry in the discovery of enzyme inhibitors

Karunakaran A Kalesh, S. Yao, Junqi Li, 2007, Nature Protocols.

Microarray immobilization of biomolecules using a fast trans-cyclooctene (TCO)-tetrazine reaction.

S. Yao, Hongyan Sun, Huatang Zhang, 2014, Chemical communications.

Preparation of small-molecule microarrays by trans-cyclooctene tetrazine ligation and their application in the high-throughput screening of protein-protein interaction inhibitors of bromodomains.

M. Uttamchandani, S. Yao, Hongyan Sun, 2013, Angewandte Chemie.

Small molecule probe suitable for in situ profiling and inhibition of protein disulfide isomerase.

L. Chong, S. Sze, P. Hao, 2013, ACS chemical biology.

Mitochondria-Targeting, Intracellular Delivery of Native Proteins Using Biodegradable Silica Nanoparticles.

S. Yao, S. S. Liew, Xiaofeng Wu, 2019, Angewandte Chemie.

Small Molecule Microarrays

S. Yao, 2010, Methods in Molecular Biology.

Cell-penetrating Mitochondria-targeting Ligands for Universal Delivery of Small Molecules, Proteins and Nanomaterials.

S. Yao, Liqian Gao, Qicai Xiao, 2021, Chemistry.

"Click" synthesis of small molecule probes for activity-based fingerprinting of matrix metalloproteases.

M. Uttamchandani, S. Yao, Jun Wang, 2006, Chemical communications.

Intracellular delivery of therapeutic proteins through N-terminal site-specific modification.

S. Yao, Cheng-wu Zhang, Hongyan Sun, 2020, Chemical communications.

Chemical proteomics of host-pathogen interaction.

S. Yao, Jingyan Ge, S. Yao, 2015, Chemistry and Biology.

The zymogen of plasmepsin V from Plasmodium falciparum is enzymatically active.

A. Wlodawer, A. Gustchina, B. C. Bryksa, 2014, Molecular and biochemical parasitology.

Small molecule probes that target Abl kinase.

Karunakaran A Kalesh, Jigang Wang, Q. Lin, 2010, Chemical communications.

"Singapore Green": a new fluorescent dye for microarray and bioimaging applications.

S. Yao, Junqi Li, S. Yao, 2009, Organic letters.

Small Molecule Microarray Based Discovery of PARP14 Inhibitors.

S. Yao, H. Schüler, A. Thorsell, 2017, Angewandte Chemie.

Inhibitor fingerprinting of metalloproteases using microplate and microarray platforms: an enabling technology in Catalomics

W. Lee, M. Uttamchandani, S. Yao, 2007, Nature Protocols.

Facile synthesis of 7-amino-4-carbamoylmethylcoumarin (ACC)-containing solid supports and their corresponding fluorogenic protease substrates.

M. Uttamchandani, S. Yao, D. Li, 2003, Bioorganic & medicinal chemistry letters.

Versatile protein biotinylation strategies for potential high-throughput proteomics.

Yi Hu, S. Yao, Rina Y P Lue, 2004, Journal of the American Chemical Society.

Combinatorial synthesis of a small-molecule library based on the vinyl sulfone scaffold.

S. Yao, Gang Wang, 2003, Organic letters.

Site-specific immobilization of proteins in a microarray using intein-mediated protein splicing.

S. Yao, Hongyan Sun, D. Yeo, 2005, Bioorganic & medicinal chemistry letters.

Global Mapping of Protein-Lipid Interactions by Using Modified Choline-Containing Phospholipids Metabolically Synthesized in Live Cells.

A. Cazenave-Gassiot, M. Wenk, S. Yao, 2017, Angewandte Chemie.

High-throughput screening of catalytically inactive mutants of protein tyrosine phosphatases (PTPs) in a phosphopeptide microarray.

S. Yao, Hongyan Sun, Liqian Gao, 2009, Chemical communications.

Fused Bicyclic Caspase-1 Inhibitors Assembled by Copper-Free Strain-Promoted Alkyne-Azide Cycloaddition (SPAAC).

S. Yao, Chong-Jing Zhang, Ji’en Wu, 2017, Chemistry.

Ugi reaction-assisted rapid assembly of affinity-based probes against potential protein tyrosine phosphatases.

S. Yao, L. Tan, Jingyan Ge, 2012, Chemical communications.

Click-based synthesis and proteomic profiling of lipstatin analogues.

M. Wenk, Pengyu Yang, S. Yao, 2010, Chemical communications.

A Vinyl Sulfone-Based Fluorogenic Probe Capable of Selective Labeling of PHGDH in Live Mammalian Cells.

S. Yao, Jun‐Seok Lee, S. S. Liew, 2018, Angewandte Chemie.

A method for small molecule microarray-based screening for the rapid discovery of affinity-based probes.

M. Uttamchandani, S. Yao, Haibin Shi, 2010, Methods in molecular biology.

In situ "click" assembly of small molecule matrix metalloprotease inhibitors containing zinc-chelating groups.

S. Yao, Junqi Li, Mingyu Hu, 2008, Organic letters.

The use of click chemistry in the emerging field of catalomics.

Karunakaran A Kalesh, S. Yao, Haibin Shi, 2010, Organic & biomolecular chemistry.

Tetrazole-Based Probes for Integrated Phenotypic Screening, Affinity-Based Proteome Profiling, and Sensitive Detection of a Cancer Biomarker.

P. Hao, S. Yao, Ke Cheng, 2017, Angewandte Chemie.

Organelle-specific detection of phosphatase activities with two-photon fluorogenic probes in cells and tissues.

S. Yao, Qinghua Xu, Lin Li, 2012, Journal of the American Chemical Society.

Solid-phase synthesis of azidomethylene inhibitors targeting cysteine proteases.

Pengyu Yang, S. Yao, Hao Wu, 2008, Organic letters.

Site-specific covalent labeling of proteins inside live cells using small molecule probes.

Shao Q Yao, S. Chattopadhaya, S. Yao, 2009, Bioorganic & medicinal chemistry.

Mito‐Bomb: Targeting Mitochondria for Cancer Therapy

S. Yao, Wei Huang, Lin Li, 2021, Advanced materials.

Expanding the chemical biologist's tool kit: chemical labelling strategies and its applications.

S. Chattopadhaya, S. Yao, Farhana B Abu Bakar, 2009, Current Medicinal Chemistry.

Intracellular Delivery of Functional Native Antibodies under Hypoxic Conditions by Using a Biodegradable Silica Nanoquencher.

S. Yao, Linghui Qian, Changmin Yu, 2017, Angewandte Chemie.

Biodegradable silica nanocapsules enable efficient nuclear-targeted delivery of native proteins for cancer therapy.

S. Yao, Liqian Gao, Qicai Xiao, 2023, Biomaterials.

Intracellular Delivery of Functional Proteins and Native Drugs by Cell-Penetrating Poly(disulfide)s.

S. Yao, Lin Li, Changmin Yu, 2015, Journal of the American Chemical Society.

Red-emitting DPSB-based conjugated polymer nanoparticles with high two-photon brightness for cell membrane imaging.

P. Liu, S. Yao, F. Huang, 2015, ACS applied materials & interfaces.

Rapid assembly and in situ screening of bidentate inhibitors of protein tyrosine phosphatases.

Mahesh Uttamchandani, Shao Q Yao, M. Uttamchandani, 2006, Organic letters.

Functionalized xenon as a biosensor

A. Pines, D. Wemmer, S. M. Rubin, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Pyridine Embedded Phenothiazinium Dyes as Lysosome-targeted Photosensitizers for Highly Efficient Photodynamic Antitumor Therapy.

Yue Jiang, S. Yao, Quanming Zhou, 2020, Journal of medicinal chemistry.

Activity-based proteome profiling of potential cellular targets of Orlistat--an FDA-approved drug with anti-tumor activities.

M. Wenk, Pengyu Yang, S. Yao, 2010, Journal of the American Chemical Society.

Mitochondria-Targeting, Intracellular Delivery of Native Proteins Using Biodegradable Silica Nanoparticles.

Shao Q Yao, Xiaofeng Wu, S. Yao, 2019, Angewandte Chemie.

Fluorescent probes for bioimaging of potential biomarkers in Parkinson's disease.

M. Brimble, S. Yao, Liqian Gao, 2020, Chemical Society reviews.

Cell-based proteome profiling of potential dasatinib targets by use of affinity-based probes.

Shao Q Yao, S. Yao, Chong-Jing Zhang, 2012, Journal of the American Chemical Society.

Intracellular Co-delivery of native antibody and siRNA for combination therapy by using biodegradable silica nanocapsules.

S. Yao, Liqian Gao, S. S. Liew, 2022, Biomaterials.

In Situ Proteome Profiling and Bioimaging Applications of Small-Molecule Affinity-Based Probes Derived From DOT1L Inhibitors.

S. Yao, Jun‐Seok Lee, Jingyan Ge, 2016, Chemistry.

Target identification of natural products and bioactive compounds using affinity-based probes.

S. Yao, Samantha C L Yao, Sijun Pan, 2016, Natural product reports.

Fluorescent probes for visualizing ROS-associated proteins in disease

S. Yao, Ping Li, Xin Wang, 2021, Chemical science.

Antibody-based fluorescence detection of kinase activity on a peptide array.

M. Lesaicherre, M. Uttamchandani, S. Yao, 2002, Bioorganic & medicinal chemistry letters.

Fluorescent Probes for Single-Step Detection and Proteomic Profiling of Histone Deacetylases.

S. Yao, Hongyan Sun, Q. Hao, 2016, Journal of the American Chemical Society.

"Minimalist" cyclopropene-containing photo-cross-linkers suitable for live-cell imaging and affinity-based protein labeling.

S. Yao, Zhengqiu Li, Lin Li, 2014, Journal of the American Chemical Society.

Target identification of biologically active small molecules via in situ methods.

Yuguo Zheng, S. Yao, Ying Su, 2013, Current opinion in chemical biology.

Design and synthesis of minimalist terminal alkyne-containing diazirine photo-crosslinkers and their incorporation into kinase inhibitors for cell- and tissue-based proteome profiling.

S. Sze, P. Hao, S. Yao, 2013, Angewandte Chemie.

Proteome profiling reveals potential cellular targets of staurosporine using a clickable cell-permeable probe.

Shao Q Yao, S. Sze, S. Yao, 2011, Chemical communications.

Recent advances in activity-based probes (ABPs) and affinity-based probes (AfBPs) for profiling of enzymes

S. Yao, Lin Li, Qiong Wu, 2021, Chemical science.

A Suite of "Minimalist" Photo-Crosslinkers for Live-Cell Imaging and Chemical Proteomics: Case Study with BRD4 Inhibitors.

S. Yao, Jun‐Seok Lee, S. S. Liew, 2017, Angewandte Chemie.

Activity based fingerprinting of proteases using FRET peptides.

S. Yao, Hongyan Sun, Resmi C. Panicker, 2007, Biopolymers.

Expanding the Chemical Biologists Tool Kit: Chemical Labelling Strategies and Its Applications

S. Chattopadhaya, S. Yao, F. A. Bakar, 2009 .

Water‐Soluble Conjugated Polymers for Simultaneous Two‐Photon Cell Imaging and Two‐Photon Photodynamic Therapy

S. Yao, Qinghua Xu, Lin Li, 2013 .

Fluorescence-activated cell sorting and directed evolution of α-N-acetylgalactosaminidases using a quenched activity-based probe (qABP).

M. Uttamchandani, S. Yao, Ying Su, 2013, Chemical communications.

Design, synthesis and biological evaluation of potent azadipeptide nitrile inhibitors and activity-based probes as promising anti-Trypanosoma brucei agents.

Cynthia Y. He, Pengyu Yang, S. Yao, 2012, Chemistry.

Iron modulates the activity of monoamine oxidase B in SH-SY5Y cells

Y. Hu, Z. Chai, S. Yao, 2017, BioMetals.

MSN‐on‐a‐Chip: Cell‐Based Screenings Made Possible on a Small‐Molecule Microarray of Native Natural Products

S. Yao, S. S. Liew, Changmin Yu, 2018, Chembiochem : a European journal of chemical biology.

Multiplex Imaging and Cellular Target Identification of Kinase Inhibitors via an Affinity-Based Proteome Profiling Approach

S. Sze, P. Hao, S. Yao, 2015, Scientific Reports.

The Expanding World of Small Molecule Microarrays.

Mahesh Uttamchandani, Shao Q Yao, M. Uttamchandani, 2017, Methods in molecular biology.

Small molecule microarrays: the first decade and beyond.

M. Uttamchandani, S. Yao, Hao Wu, 2011, Chemical communications.

Recent developments in microarray-based enzyme assays: from functional annotation to substrate/inhibitor fingerprinting

S. Chattopadhaya, S. Yao, Jun Wang, 2006, Analytical and bioanalytical chemistry.

Small molecule microarrays: recent advances and applications.

Mahesh Uttamchandani, Shao Q Yao, Daniel P Walsh, 2005, Current opinion in chemical biology.

Protein-Protein Interaction Inhibitors of BRCA1 Discovered Using Small Molecule Microarrays.

M. Uttamchandani, S. Yao, Zhenkun Na, 2017, Methods in molecular biology.

Discovery of cell-permeable inhibitors that target the BRCT domain of BRCA1 protein by using a small-molecule microarray.

M. Uttamchandani, S. Yao, Zhenkun Na, 2014, Angewandte Chemie.

Current chemical biology tools for studying protein phosphorylation and dephosphorylation.

Shao Q Yao, Kai Liu, S. Yao, 2012, Chemistry.

Peptide-based activity-based probes (ABPs) for target-specific profiling of protein tyrosine phosphatases (PTPs).

Karunakaran A Kalesh, S. Yao, Liqian Gao, 2010, Chemical communications.

Click Chemistry as a High‐Throughput Amenable Platform in Catalomics

Karunakaran A Kalesh, Pengyu Yang, S. Yao, 2007 .

Modulation of fatty acid synthase enzyme activity and expression during hepatitis C virus replication.

John Paul Pezacki, Shao Yao, Pengyu Yang, 2013, Chemistry & biology.

Phosphopeptide microarrays for comparative proteomic profiling of cellular lysates.

M. Uttamchandani, S. Yao, Hongyan Sun, 2013, Methods in molecular biology.

A proteomic strategy for the identification of caspase-associating proteins.

S. Yao, Resmi C. Panicker, Grace Y. J. Chen, 2005, Chemical communications.

Recent advances in microarray technologies for proteomics.

Hongyan Sun, Shao Q Yao, S. Yao, 2013, Chemistry & biology.

Peptide-Based Microarray

S. Yao, Hongyan Sun, Resmi C. Panicker, 2009 .

Use of intein-mediated protein ligation strategies for the fabrication of functional protein arrays.

S. Chattopadhaya, S. Yao, Farhana B Abu Bakar, 2009, Methods in enzymology.

Nanodroplet profiling of enzymatic activities in a microarray.

Xuan Huang, Mahesh Uttamchandani, Shao Q Yao, 2005, Bioorganic & medicinal chemistry letters.

Application of microarrays in high-throughput enzymatic profiling

M. Uttamchandani, S. Yao, Xuan Huang, 2004, Molecular biotechnology.

Site-specific immobilization of biotinylated proteins for protein microarray analysis.

M. Lesaicherre, S. Yao, Rina Y P Lue, 2004, Methods in molecular biology.

Developing a Strategy for Activity‐Based Detection of Enzymes in a Protein Microarray

M. Uttamchandani, S. Yao, Gang Wang, 2003, Chembiochem : a European journal of chemical biology.

Enzymatic profiling system in a small-molecule microarray.

M. Lesaicherre, M. Uttamchandani, S. Yao, 2003, Organic letters.

Developing site-specific immobilization strategies of peptides in a microarray.

M. Lesaicherre, M. Uttamchandani, S. Yao, 2002, Bioorganic & medicinal chemistry letters.

In Vivo Imaging of a Bacterial Cell Division Protein Using a Protease‐Assisted Small‐Molecule Labeling Approach

S. Chattopadhaya, S. Yao, Farhana B Abu Bakar, 2008, Chembiochem : a European journal of chemical biology.

A sensitive two-photon probe to selectively detect monoamine oxidase B activity in Parkinson’s disease models

K. Lim, C. Chai, S. Yao, 2014, Nature Communications.

Two-Photon Small Molecule Enzymatic Probes.

Lin Li, Shao Q Yao, S. Yao, 2016, Accounts of chemical research.

A tuned affinity-based staurosporine probe for in situ profiling of protein kinases.

M. Uttamchandani, S. Yao, Lin Li, 2014, Chemical communications.

Cell-based proteome profiling using an affinity-based probe (AfBP) derived from 3-deazaneplanocin A (DzNep).

S. Yao, C. Chai, Zhengqiu Li, 2013, Chemistry, an Asian journal.

Targeting Lipid Esterases in Mycobacteria Grown Under Different Physiological Conditions Using Activity-based Profiling with Tetrahydrolipstatin (THL)*

A. Cazenave-Gassiot, M. Wenk, S. Yao, 2013, Molecular & Cellular Proteomics.

Conjugated-polymer-based red-emitting nanoparticles for two-photon excitation cell imaging with high contrast.

S. Yao, Qinghua Xu, Lin Li, 2014, Langmuir : the ACS journal of surfaces and colloids.

Strategies for site-specific protein biotinylation using in vitro, in vivo and cell-free systems: toward functional protein arrays

S. Chattopadhaya, S. Yao, L. Tan, 2006, Nature Protocols.

A small-molecule protein-protein interaction inhibitor of PARP1 that targets its BRCT domain.

S. Yao, Han-Ming Shen, Jun‐Seok Lee, 2015, Angewandte Chemie.

Activity-based high-throughput screening of enzymes by using a DNA microarray.

Yi Hu, S. Yao, Grace Y. J. Chen, 2005, Angewandte Chemie.

A switchable two-photon membrane tracer capable of imaging membrane-associated protein tyrosine phosphatase activities.

S. Yao, Qinghua Xu, Lin Li, 2013, Angewandte Chemie.

In situ imaging and proteome profiling indicate andrographolide is a highly promiscuous compound

S. Yao, Lin Li, Y. Lam, 2015, Scientific Reports.

Cell-penetrating poly(disulfide)-based star polymers for simultaneous intracellular delivery of miRNAs and small molecule drugs

S. Yao, Shuizhu Wu, Yang Wenhua, 2017 .

Single-Vehicular Delivery of Antagomir and Small Molecules to Inhibit miR-122 Function in Hepatocellular Carcinoma Cells by using "Smart" Mesoporous Silica Nanoparticles.

M. Uttamchandani, S. Yao, Linghui Qian, 2015, Angewandte Chemie.

Profiling human Src homology 2 (SH2) domain proteins and ligand discovery using a peptide-hybrid small molecule microarray.

M. Uttamchandani, S. Yao, Jiaqi Fu, 2013, Chemical communications.

Comparative proteomic profiling of mammalian cell lysates using phosphopeptide microarrays.

M. Uttamchandani, S. Yao, Liqian Gao, 2012, Chemical communications.

Dynamic monitoring of newly synthesized proteomes: up-regulation of myristoylated protein kinase A during butyric acid induced apoptosis.

Pengyu Yang, S. Yao, Kai Liu, 2011, Angewandte Chemie.

Peptide microarrays: next generation biochips for detection, diagnostics and high-throughput screening.

M. Uttamchandani, S. Yao, S. Yao, 2008, Current pharmaceutical design.

Rapid synthesis of flavone‐based monoamine oxidase (MAO) inhibitors targeting two active sites using click chemistry

S. Yao, Yin Jun Zhang, Jingyan Ge, 2017, Chemical biology & drug design.

Parasite-based screening and proteome profiling reveal orlistat, an FDA-approved drug, as a potential anti Trypanosoma brucei agent.

Cynthia Y. He, S. Sze, Pengyu Yang, 2012, Chemistry.

Developing new chemical tools for DNA methyltransferase 1 (DNMT 1): a small-molecule activity-based probe and novel tetrazole-containing inhibitors.

S. Yao, Jingyan Ge, Biwei Zhu, 2015, Bioorganic & medicinal chemistry.

Quantitative inhibitor fingerprinting of metalloproteases using small molecule microarrays.

W. Lee, M. Uttamchandani, S. Yao, 2007, Journal of the American Chemical Society.

Microarrays of tagged combinatorial triazine libraries in the discovery of small-molecule ligands of human IgG.

Xuan Huang, Mahesh Uttamchandani, Shao Q Yao, 2004, Journal of combinatorial chemistry.

An unnatural amino acid that mimics phosphotyrosine.

S. Yao, Hao Wu, Jingyan Ge, 2010, Chemical communications.

De Novo Designed Self-Assembling Rhodamine Probe for Real-Time, Long-Term and Quantitative Live-Cell Nanoscopy.

S. Yao, Hongyan Sun, Ke Cheng, 2023, ACS nano.

Gold nanorod enhanced two-photon excitation fluorescence of photosensitizers for two-photon imaging and photodynamic therapy.

G. Xu, S. Yao, Qinghua Xu, 2014, ACS applied materials & interfaces.

Internal standard fluorogenic probe based on vibration-induced emission for visualizing PTP1B in living cells.

S. Yao, Lin Li, Wei Huang, 2019, Chemical communications.

Pin1 Catalyzes Conformational Changes of Thr-187 in p27Kip1 and Mediates Its Stability through a Polyubiquitination Process*

A. Ryo, W. Zhou, Y. Liou, 2009, The Journal of Biological Chemistry.

Peptide microarray for high-throughput determination of phosphatase specificity and biology.

Y. Liou, M. Uttamchandani, S. Yao, 2008, Angewandte Chemie.

Site-specific immobilization of biomolecules by a biocompatible reaction between terminal cysteine and 2-cyanobenzothiazole.

S. Yao, Hongyan Sun, Chong-Jing Zhang, 2013, Chemical communications.

One- and two-photon live cell imaging using a mutant SNAP-Tag protein and its FRET substrate pairs.

S. Yao, Qinghua Xu, Chong-Jing Zhang, 2011, Organic letters.

Cell-Active, Reversible, and Irreversible Covalent Inhibitors that Selectively Target the Catalytic Lysine of BCR-ABL Kinase.

S. Yao, Liqian Gao, Menghua Xiang, 2022, Angewandte Chemie.

An Improved Mechanism‐Based Cross‐Linker for Multiplexed Kinase Detection and Inhibition in a Complex Proteome

Karunakaran A Kalesh, S. Yao, Kai Liu, 2008, Chembiochem : a European journal of chemical biology.

Highly efficient, conjugated-polymer-based nano-photosensitizers for selectively targeted two-photon photodynamic therapy and imaging of cancer cells.

S. Yao, Qinghua Xu, Lin Li, 2015, Chemistry.

Photosensitizer-doped conjugated polymer nanoparticles for simultaneous two-photon imaging and two-photon photodynamic therapy in living cells.

Shao Q Yao, Qing-Hua Xu, Hao Wu, 2011, Nanoscale.

Gold nanorods as dual photo-sensitizing and imaging agents for two-photon photodynamic therapy.

G. Xu, S. Yao, Qinghua Xu, 2012, Nanoscale.

The Dawn of a New Era: Targeting the "Undruggables" with Antibody-Based Therapeutics.

S. Yao, Linghui Qian, R. Khan, 2023, Chemical reviews.

Intein-mediated biotinylation of proteins and its application in a protein microarray.

Qing Zhu, Shao Q Yao, M. Lesaicherre, 2002, Journal of the American Chemical Society.

Engineered Cell-Penetrating Peptides for Mitochondrion-Targeted Drug Delivery in Cancer Therapy.

S. Yao, Liqian Gao, Qicai Xiao, 2021, Chemistry.

Recent Advances in Polymeric Nanoparticles for Enhanced Fluorescence and Photoacoustic Imaging.

S. Yao, Changyu Zhang, Sing Yee Ong, 2021, Angewandte Chemie.

Cell-Penetrating Poly(disulfide) Assisted Intracellular Delivery of Mesoporous Silica Nanoparticles for Inhibition of miR-21 Function and Detection of Subsequent Therapeutic Effects.

S. Yao, Linghui Qian, Changmin Yu, 2016, Angewandte Chemie.

Recent Advances in Polymeric Nanoparticles for Enhanced Fluorescence and Photoacoustic Imaging

S. Yao, Changyu Zhang, Sing Yee Ong, 2021, Angewandte Chemie.

Stimulus-responsive self-assembled prodrugs in cancer therapy

S. Yao, Xiaowu Dong, R. K. Brahma, 2022, Chemical science.

Nanocomposites containing gold nanorods and porphyrin-doped mesoporous silica with dual capability of two-photon imaging and photosensitization.

Shao Q Yao, Guo Qin Xu, Qing-Hua Xu, 2010, Langmuir : the ACS journal of surfaces and colloids.

Current advances in peptide and small molecule microarray technologies.

M. Uttamchandani, S. Yao, Jiaqi Fu, 2012, Current opinion in chemical biology.

Inhibitor fingerprinting of matrix metalloproteases using a combinatorial peptide hydroxamate library.

M. Uttamchandani, S. Yao, Jun Wang, 2007, Journal of the American Chemical Society.

A targeted covalent inhibitor of p97 with proteome-wide selectivity

S. Yao, Chong-Jing Zhang, Zhiqiang Feng, 2021, Acta pharmaceutica Sinica. B.

Simultaneous Imaging of Endogenous Survivin mRNA and On-Demand Drug Release in Live Cells by Using a Mesoporous Silica Nanoquencher.

S. Yao, Shuizhu Wu, Changmin Yu, 2017, Small.

Two‐Photon Small‐Molecule Fluorogenic Probes for Visualizing Endogenous Nitroreductase Activities from Tumor Tissues of a Cancer Patient

S. Yao, Liqian Gao, Qiong Wu, 2022, Advanced healthcare materials.

Strategic Design of Catalytic Lysine-Targeting Reversible Covalent BCR-ABL Inhibitors.

Rong Li, A. Poulsen, S. Yao, 2021, Angewandte Chemie.

Bifunctional Lipid-Derived Affinity-Based Probes (AfBPs) for Analysis of Lipid-Protein Interactome.

S. Yao, Shubo Du, Jingyan Ge, 2022, Accounts of chemical research.

2-Ethynylbenzaldehyde-Based, Lysine-Targeting Irreversible Covalent Inhibitors for Protein Kinases and Nonkinases.

S. Yao, Liqian Gao, Lin Li, 2023, Journal of the American Chemical Society.

Applying small molecule microarrays and resulting affinity probe cocktails for proteome profiling of mammalian cell lysates.

M. Uttamchandani, S. Yao, Haibin Shi, 2011, Chemistry, an Asian journal.

A peptide aldehyde microarray for high-throughput profiling of cellular events.

Jigang Wang, M. Uttamchandani, S. Yao, 2011, Journal of the American Chemical Society.

Microarray-assisted high-throughput identification of a cell-permeable small-molecule binder of 14-3-3 proteins.

S. Yao, Hao Wu, Jingyan Ge, 2010, Angewandte Chemie.

Accelerated cellular on- and off-target screening of bioactive compounds using microarrays.

M. Uttamchandani, S. Yao, Jiaqi Fu, 2016, Organic & biomolecular chemistry.

Controlled proliferation and screening of mammalian cells on a hydrogel-functionalized small molecule microarray.

S. Yao, Bo Jiang, Zhenkun Na, 2015, Chemical communications.

Screening Mammalian Cells on a Hydrogel: Functionalized Small Molecule Microarray.

S. Yao, Bo Jiang, Zhenkun Na, 2017, Methods in molecular biology.

Cell type-selective imaging and profiling of newly synthesized proteomes by using puromycin analogues.

S. Yao, Jun‐Seok Lee, Shubo Du, 2017, Chemical communications.

Combinatorial peptide microarrays for the rapid determination of kinase specificity.

Mahesh Uttamchandani, Shao Q Yao, M. Uttamchandani, 2003, Bioorganic & medicinal chemistry letters.

Peptide microarrays for high-throughput studies of Ser/Thr phosphatases

S. Yao, Hongyan Sun, Liqian Gao, 2008, Nature Protocols.

Activity-based high-throughput determination of PTPs substrate specificity using a phosphopeptide microarray.

S. Yao, Hongyan Sun, Liqian Gao, 2010, Biopolymers.

Design and synthesis of an affinity probe that targets caspases in proteomic experiments

S. Yao, Resmi C. Panicker, Ming-Lee Liau, 2003 .

A Versatile Microarray Immobilization Strategy Based on a Biorthogonal Reaction Between Tetrazine and Trans-Cyclooctene.

Su Seong Lee, S. Yao, Hongyan Sun, 2017, Methods in molecular biology.

Bidentate inhibitors of protein tyrosine phosphatases.

S. Yao, C. Chai, J. Low, 2014, Antioxidants & redox signaling.

Co-delivery of proteins and small molecule drugs for mitochondria-targeted combination therapy.

S. Yao, S. S. Liew, Lin Li, 2021, Chemical communications.

Proteome analysis of Saccharomyces cerevisiae under metal stress by two‐dimensional differential gel electrophoresis

Gang Wang, Shao Q Yao, Yi Hu, 2003, Electrophoresis.

Small Molecule Microarrays: Applications Using Specially Tagged Chemical Libraries

Jun Wang, Mahesh Uttamchandani, Hongyan Sun, 2006 .

Functional profiling, identification, and inhibition of plasmepsins in intraerythrocytic malaria parasites.

Young‐Tae Chang, R. Yada, S. Yao, 2009, Angewandte Chemie.

Next generation chemical proteomic tools for rapid enzyme profiling.

M. Uttamchandani, S. Yao, Candy H. S. Lu, 2009, Accounts of chemical research.

Activity‐Based Fingerprinting of Proteases

S. Yao, Xuan Huang, R. Srinivasan, 2006, Chembiochem : a European journal of chemical biology.

Recent advances in gel-based proteome profiling techniques

Yi Hu, S. Yao, Xuan Huang, 2004, Molecular biotechnology.

Design and synthesis of fluorogenic substrates that target protein phosphatases

S. Yao, Xuan Huang, Grace Y. J. Chen, 2004 .

Activity-based fluorescent probes that target phosphatases

S. Yao, Xuan Huang, Grace Y. J. Chen, 2003 .

Site-specific peptide immobilization strategies for the rapid detection of kinase activity on microarrays.

M. Lesaicherre, M. Uttamchandani, S. Yao, 2004, Methods in molecular biology.

In Vitro and In Vivo Demonstration of Ultraefficient and Broad-Spectrum Antibacterial Agents for Photodynamic Antibacterial Chemotherapy.

Bingjie Mai, Chuang Yuan, S. Yao, 2021, ACS applied materials & interfaces.

Mitochondria-Targeted Gene Silencing Facilitated by Mito-CPDs.

S. Yao, W. Tan, Jingyan Ge, 2023, Chemistry.

Cell-penetrating poly(disulfide)-based nanoquenchers (qCPDs) for self-monitoring of intracellular gene delivery.

S. Yao, S. S. Liew, Shubo Du, 2022, Chemical communications.

In vivo targeted delivery of antibodies into cancer cells with pH-responsive cell-penetrating poly(disulfide)s.

Qihao Weng, S. Yao, Linghui Qian, 2022, Chemical communications.

Chemical Probes Reveal Sirt2's New Function as a Robust "Eraser" of Lysine Lipoylation.

Jigang Wang, S. Yao, Hongyan Sun, 2019, Journal of the American Chemical Society.

Cell-permeable small molecule probes for site-specific labeling of proteins.

M. Uttamchandani, S. Yao, D. Yeo, 2003, Chemical communications.

Ugi reaction-assisted assembly of covalent PROTACs against glutathione peroxidase 4.

S. Yao, Jingyan Ge, Shiqi Hu, 2023, Bioorganic chemistry.

Activity-based high-throughput profiling of metalloprotease inhibitors using small molecule microarrays.

M. Uttamchandani, S. Yao, Jun Wang, 2006, Chemical communications.

Strategies for immobilization of biomolecules in a microarray.

S. Yao, Resmi C. Panicker, D. Yeo, 2004, Combinatorial chemistry & high throughput screening.

Novel Electrophilic Warhead Targeting a Triple-Negative Breast Cancer Driver in Live Cells Revealed by "Inverse Drug Discovery".

Huilin Li, S. Yao, Hongyan Sun, 2021, Journal of medicinal chemistry.

Advanced analytical tools in proteomics.

S. Chattopadhaya, S. Yao, Resmi C. Panicker, 2006, Analytica chimica acta.

Nanodroplet microarrays for high-throughput enzyme screening.

M. Uttamchandani, S. Yao, K. D. Aw, 2010, Methods in molecular biology.

Cell-active, irreversible covalent inhibitors that selectively target the catalytic lysine of EGFR by using fluorosulfate-based SuFEx chemistry.

S. Sze, So Fong Cam Ngan, S. Yao, 2023, European journal of medicinal chemistry.

Expanding the scope of site-specific protein biotinylation strategies using small molecules.

S. Yao, Grace Y. J. Chen, L. Tan, 2004, Bioorganic & medicinal chemistry letters.

Cell‐Permeable Small Molecule Probes for Site‐Specific Labeling of Proteins.

M. Uttamchandani, S. Yao, D. Yeo, 2004 .

The Use of Click Chemistry in the Emerging Field of Catalomics

S. Yao, Haibin Shi, Jingyan Ge, 2010 .

High-throughput discovery of Mycobacterium tuberculosis protein tyrosine phosphatase B (MptpB) inhibitors using click chemistry.

Karunakaran A Kalesh, Xiaohua Zhang, Pengyu Yang, 2009, Organic letters.

Modulation of fatty acid synthase enzyme activity and expression during hepatitis C virus replication.

D. Tyrrell, S. Yao, Neda Nasheri, 2013, Chemistry & biology.