Wenhui Li

发表

Structure of SARS Coronavirus Spike Receptor-Binding Domain Complexed with Receptor

S. Harrison, Fang Li, Wenhui Li, 2005, Science.

Conformational States of the Severe Acute Respiratory Syndrome Coronavirus Spike Protein Ectodomain

Wenhui Li, Fang Li, S. Harrison, 2006, Journal of Virology.

Influenza A Virus Neuraminidase Limits Viral Superinfection

Wenhui Li, W. Marasco, Wenhui Li, 2008, Journal of Virology.

Tyrosine Sulfation of Human Antibodies Contributes to Recognition of the CCR5 Binding Region of HIV-1 gp120

Christoph Grundner, Peter D. Kwong, Wenhui Li, 2003, Cell.

The S proteins of human coronavirus NL63 and severe acute respiratory syndrome coronavirus bind overlapping regions of ACE2

J. Kuhn, S. Radoshitzky, W. Marasco, 2007, Virology.

Severe Acute Respiratory Syndrome Coronavirus Entry as a Target of Antiviral Therapies

J. Kuhn, S. Radoshitzky, Wenhui Li, 2005, Antiviral therapy.

Insights from the Association of SARS-CoV S-Protein with its Receptor, ACE2

Wenhui Li, M. Farzan, H. Choe, 2006, Advances in experimental medicine and biology.

A POTENTIAL TARGET FOR ANTIVIRAL

J. Kuhn, S. Radoshitzky, Wenhui Li, 2006 .

The SARS Coronavirus receptor ACE 2 A potential target for antiviral therapy

J. Kuhn, S. Radoshitzky, Wenhui Li, 2006, New Concepts of Antiviral Therapy.

Increased sulfation of bile acids in mice and human subjects with sodium taurocholate cotransporting polypeptide deficiency

C. Borchers, Wenhui Li, J. Sui, 2019, The Journal of Biological Chemistry.

Modification of Three Amino Acids in Sodium Taurocholate Cotransporting Polypeptide Renders Mice Susceptible to Infection with Hepatitis D Virus In Vivo

Wenhui Li, J. Sui, F. Mao, 2016, Journal of Virology.

Receptor and viral determinants of SARS-coronavirus adaptation to human ACE2

Chengsheng Zhang, Wenhui Li, Jens H Kuhn, 2005, The EMBO journal.

Interactions Between Sars Coronavirus and its Receptor

S. Harrison, Fang Li, Wenhui Li, 2006, Advances in experimental medicine and biology.

Receptor-Binding Domain of Spike Protein Coronaviruses by Antibodies Targeting the Civet Severe Acute Respiratory Syndrome Cross-Neutralization of Human and Palm

Shibo Jiang, Wenhui Li, M. Farzan, 2006 .

Efficient Replication of Severe Acute Respiratory Syndrome Coronavirus in Mouse Cells Is Limited by Murine Angiotensin-Converting Enzyme 2

T. Greenough, Wenhui Li, M. Farzan, 2004, Journal of Virology.

A research agenda for curing chronic hepatitis B virus infection

C. Rice, F. Chisari, B. McMahon, 2018, Hepatology.

Sodium Taurocholate Cotransporting Polypeptide Acts as a Receptor for Hepatitis B and D Virus

Wenhui Li, Huan Yan, 2015, Digestive Diseases.

Research priorities for the discovery of a cure for chronic hepatitis B: Report of a workshop

C. Rice, B. McMahon, A. Lok, 2017, Antiviral research.

Viral Entry of Hepatitis B and D Viruses and Bile Salts Transportation Share Common Molecular Determinants on Sodium Taurocholate Cotransporting Polypeptide

Wenhui Li, J. Sui, Guangwei Xu, 2014, Journal of Virology.

Human Coronavirus HKU1 Spike Protein Uses O-Acetylated Sialic Acid as an Attachment Receptor Determinant and Employs Hemagglutinin-Esterase Protein as a Receptor-Destroying Enzyme

R. Baric, K. Pyrć, W. Marasco, 2015, Journal of Virology.

Sodium taurocholate cotransporting polypeptide is a functional receptor for human hepatitis B and D virus.

Wenhui Li, J. Sui, Xiaofeng Feng, 2012, eLife.

Tyrosine-sulfated Peptides Functionally Reconstitute a CCR5 Variant Lacking a Critical Amino-terminal Region*

J. Sodroski, C. Schnitzler, Wenhui Li, 2002, The Journal of Biological Chemistry.

NTCP Deficiency Causes Gallbladder Abnormalities in Mice and Human Beings

Wenhui Li, J. Sui, F. Mao, 2020, Cellular and molecular gastroenterology and hepatology.

Nonmuscle Myosin Heavy Chain IIA Is a Critical Factor Contributing to the Efficiency of Early Infection of Severe Fever with Thrombocytopenia Syndrome Virus

Wenhui Li, Wenqing Gao, Zhiyi Jing, 2013, Journal of Virology.

Development and Evaluation of a Pseudovirus-Luciferase Assay for Rapid and Quantitative Detection of Neutralizing Antibodies against Enterovirus 71

Wenhui Li, Junzhi Wang, Zhenglun Liang, 2013, PloS one.

HBV core protein allosteric modulators differentially alter cccDNA biosynthesis from de novo infection and intracellular amplification pathways

Wenhui Li, Jinhong Chang, A. Cuconati, 2017, PLoS pathogens.

DNA Polymerase κ Is a Key Cellular Factor for the Formation of Covalently Closed Circular DNA of Hepatitis B Virus

Wenhui Li, Ju-Tao Guo, Guangwei Xu, 2016, PLoS pathogens.

NTCP-Reconstituted In Vitro HBV Infection System.

Wenhui Li, B. Peng, Yonghe Qi, 2017, Methods in molecular biology.

NTCP and Beyond: Opening the Door to Unveil Hepatitis B Virus Entry

Wenhui Li, T. Wakita, S. Urban, 2014, International journal of molecular sciences.

Severe fever with thrombocytopenia syndrome phlebovirus non-structural protein activates TPL2 signalling pathway for viral immunopathogenesis

P. Tsichlis, Jae U. Jung, Su-Jin Park, 2019, Nature Microbiology.

Molecular Determinants of Hepatitis B and D Virus Entry Restriction in Mouse Sodium Taurocholate Cotransporting Polypeptide

Wenhui Li, J. Sui, Guangwei Xu, 2013, Journal of Virology.

A quantitative method for hepatitis B virus covalently closed circular DNA enables distinguishing direct acting antivirals from cytotoxic agents.

Wenhui Li, Zhenchao Gao, Liwei Yan, 2019, Antiviral research.

Animal models for the study of human hepatitis B and D virus infection: new insights and progress.

Wenhui Li, B. Burwitz, Zhongmin Zhou, 2020, Antiviral research.

Recombinant vaccinia vector-based vaccine (Tiantan) boosting a novel HBV subunit vaccine induced more robust and lasting immunity in rhesus macaques.

W. Tan, Wenhui Li, Yao Deng, 2017, Vaccine.

Molecular Determinants of Enterovirus 71 Viral Entry

Wenhui Li, Zhenglun Liang, Xinliang Shen, 2012, The Journal of Biological Chemistry.

Potent neutralization of severe acute respiratory syndrome (SARS) coronavirus by a human mAb to S1 protein that blocks receptor association.

Wenhui Li, W. Bellini, W. Marasco, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Sodium taurocholate cotransporting polypeptide is a functional receptor for human hepatitis B and D virus

Wenhui Li, Wenhui He, Wenhui Li, 2012, eLife.

Sulphated tyrosines mediate association of chemokines and Plasmodium vivax Duffy binding protein with the Duffy antigen/receptor for chemokines (DARC)

C. M. Owens, C. Chitnis, Wenhui Li, 2005, Molecular microbiology.

Transferrin receptor 1 is a cellular receptor for New World haemorrhagic fever arenaviruses

Jens H. Kuhn, Wenhui Li, N. Andrews, 2007, Nature.

Alpha-Interferon Suppresses Hepadnavirus Transcription by Altering Epigenetic Modification of cccDNA Minichromosomes

Wenhui Li, Jinhong Chang, T. Block, 2013, PLoS pathogens.

A global scientific strategy to cure hepatitis B.

Joan M. Block, J. Fellay, F. Chisari, 2019, The lancet. Gastroenterology & hepatology.

Receptor-binding domain of SARS-CoV spike protein induces highly potent neutralizing antibodies: implication for developing subunit vaccine

Shibo Jiang, Wenhui Li, Shibo Jiang, 2004, Biochemical and Biophysical Research Communications.

The SARS-CoV-2 receptor-binding domain elicits a potent neutralizing response without antibody-dependent enhancement

Wenhui Li, M. Farzan, M. Parcells, 2020, bioRxiv.

The hepatitis B virus receptor.

Wenhui Li, Wenhui Li, 2015, Annual review of cell and developmental biology.

NTCP opens the door for hepatitis B virus infection.

Wenhui Li, Yang Liu, Wenhui Li, 2015, Antiviral research.

Hepatitis D Virus Infection of Mice Expressing Human Sodium Taurocholate Co-transporting Polypeptide

Wenhui Li, J. Sui, F. Mao, 2015, PLoS pathogens.

A potent human neutralizing antibody Fc-dependently reduces established HBV infections

K. Ye, Wenhui Li, J. Sui, 2017, eLife.

The immune response of rhesus macaques to novel vaccines comprising hepatitis B virus S, PreS1, and Core antigens.

Baoying Huang, W. Tan, Wenhui Li, 2018, Vaccine.

Sodium Taurocholate Cotransporting Polypeptide Mediates Woolly Monkey Hepatitis B Virus Infection of Tupaia Hepatocytes

Wenhui Li, J. Sui, Xiaofeng Feng, 2013, Journal of Virology.

Silencing Retinoid X Receptor Alpha Expression Enhances Early-Stage Hepatitis B Virus Infection In Cell Cultures

Wenhui Li, Guangwei Xu, Wenhui He, 2018, Journal of Virology.

The p.Ser267Phe variant of sodium taurocholate cotransporting polypeptide (NTCP) supports HBV infection with a low efficiency.

Wenhui Li, J. Sui, Zhongmin Zhou, 2018, Virology.

Cross-Neutralization of Human and Palm Civet Severe Acute Respiratory Syndrome Coronaviruses by Antibodies Targeting the Receptor-Binding Domain of Spike Protein

Shibo Jiang, Wenhui Li, Shibo Jiang, 2006, The Journal of Immunology.

A 193-Amino Acid Fragment of the SARS Coronavirus S Protein Efficiently Binds Angiotensin-converting Enzyme 2*

Wenhui Li, Wenhui Li, M. Farzan, 2004, Journal of Biological Chemistry.

Transcriptionally inactive hepatitis B virus episome DNA preferentially resides in the vicinity of chromosome 19 in 3D host genome upon infection.

Wenhui Li, J. Sui, J. Duan, 2021, Cell reports.

microRNA expression in hepatitis B virus infected primary treeshrew hepatocytes and the independence of intracellular miR-122 level for de novo HBV infection in culture.

Wenhui Li, Yanting Ma, Xiaofeng Feng, 2014, Virology.

Dual-targeting nanoparticle vaccine elicits a therapeutic antibody response against chronic hepatitis B

P. Zhu, Wenhui Li, Xiyun Yan, 2020, Nature Nanotechnology.

SARS Coronavirus, but Not Human Coronavirus NL63, Utilizes Cathepsin L to Infect ACE2-expressing Cells

S. Harrison, P. Dormitzer, B. Bosch, 2006, Journal of Biological Chemistry.

Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus

John L. Sullivan, Wenhui Li, Katherine Luzuriaga, 2003, Nature.

Nonproductive Hepatitis B Virus Covalently Closed Circular DNA Generates HBx-Related Transcripts from the HBx/Enhancer I Region and Acquires Reactivation by Superinfection in Single Cells

Wenhui Li, Zhiyi Jing, B. Peng, 2022, Journal of virology.

Retroviruses Pseudotyped with the Severe Acute Respiratory Syndrome Coronavirus Spike Protein Efficiently Infect Cells Expressing Angiotensin-Converting Enzyme 2

Jens H. Kuhn, Wenhui Li, T. Greenough, 2004, Journal of Virology.

SARS-CoV-2 spike-protein D614G mutation increases virion spike density and infectivity

Haiyong Peng, Wenhui Li, M. Farzan, 2020, Nature Communications.

Receptor Usage of a Novel Bat Lineage C Betacoronavirus Reveals Evolution of Middle East Respiratory Syndrome-Related Coronavirus Spike Proteins for Human Dipeptidyl Peptidase 4 Binding

P. Woo, Jian-Piao Cai, J. Chan, 2018, The Journal of infectious diseases.

Development and effectiveness of pseudotyped SARS-CoV-2 system as determined by neutralizing efficiency and entry inhibition test in vitro

Wenling Wang, Baoying Huang, W. Tan, 2020, Biosafety and Health.

Antibody responses against SARS coronavirus are correlated with disease outcome of infected individuals

D. Ho, Zhiwei Chen, K. Yuen, 2005, Journal of medical virology.

TIM-family Proteins Promote Infection of Multiple Enveloped Viruses through Virion-associated Phosphatidylserine

G. Freeman, D. Umetsu, Wenhui Li, 2013, PLoS pathogens.

Animal Origins of the Severe Acute Respiratory Syndrome Coronavirus: Insight from ACE2-S-Protein Interactions

J. Kuhn, Fang Li, Wenhui Li, 2006, Journal of Virology.

Angiotensin-Converting Enzyme 2, the Cellular Receptor for Severe Acute Respiratory Syndrome Coronavirus and Human Coronavirus NL63

Wenhui Li, M. Farzan, H. Choe, 2008 .

SARS-CoV, But not HCoV-NL63, Utilizes Cathepsins to Infect Cells: Viral Entry

B. Bosch, Wenhui Li, M. Farzan, 2006, Advances in experimental medicine and biology.

Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus.

Wenhui Li, Katherine Luzuriaga, John L Sullivan, 2004, Nature.

Structural basis for activation and inhibition of the secreted chlamydia protease CPAF.

J. Chai, Ding Chen, G. Zhong, 2008, Cell host & microbe.

An Engineered Receptor-Binding Domain Improves the Immunogenicity of Multivalent SARS-CoV-2 Vaccines

Wenhui Li, M. Farzan, M. Parcells, 2021, mBio.

An engineered receptor-binding domain improves the immunogenicity of multivalent SARS-CoV-2 vaccines

Wenhui Li, M. Farzan, M. Parcells, 2020, bioRxiv.

Woodchuck sodium taurocholate cotransporting polypeptide supports low-level hepatitis B and D virus entry.

Wenhui Li, Zhiyi Jing, Hongjie Hu, 2017, Virology.

Entry of hepatitis B and hepatitis D virus into hepatocytes: Basic insights and clinical implications

Wenhui Li, S. Urban, 2016, Journal of Hepatology.

Abnormal Bilirubin Metabolism in Patients With Sodium Taurocholate Cotransporting Polypeptide Deficiency

K. Setchell, Wenhui Li, Jian-She Wang, 2020, Journal of pediatric gastroenterology and nutrition.

Evaluation of Human Monoclonal Antibody 80R for Immunoprophylaxis of Severe Acute Respiratory Syndrome by an Animal Study, Epitope Mapping, and Analysis of Spike Variants

Wenhui Li, K. Subbarao, A. Roberts, 2005, Journal of Virology.

Cryo-electron Microscopy Structure of S-Trimer, a Subunit Vaccine Candidate for COVID-19

Wenhui Li, Xueqin Huang, P. Liang, 2021, Journal of Virology.

Conserved Receptor-binding Domains of Lake Victoria Marburgvirus and Zaire Ebolavirus Bind a Common Receptor*

J. Kuhn, S. Radoshitzky, M. Aman, 2006, Journal of Biological Chemistry.

Novel Abs targeting the N‐terminus of fibroblast growth factor 19 inhibit hepatocellular carcinoma growth without bile‐acid‐related side‐effects

Wenhui Li, J. Sui, Sanduo Zheng, 2020, Cancer science.

Correction: Sodium taurocholate cotransporting polypeptide is a functional receptor for human hepatitis B and D virus

Wenhui Li, J. Sui, Xiaofeng Feng, 2014, eLife.

Site-specific engineering of chemical functionalities on the surface of live hepatitis D virus.

Lin Li, Wenhui Li, Peng R. Chen, 2013, Angewandte Chemie.

Lack of antibody-mediated cross-protection between SARS-CoV-2 and SARS-CoV infections

Wenling Wang, Baoying Huang, Wenhui Li, 2020, EBioMedicine.

A spatiotemporally controlled recombinant cccDNA mouse model for studying HBV and developing drugs against the virus

Wenhui Li, Zhongmin Zhou, Fengchao Wang, 2023, Antiviral Research.

SLF2 Interacts with the SMC5/6 Complex to Direct Hepatitis B Virus Episomal DNA to Promyelocytic Leukemia Bodies for Transcriptional Repression

Wenhui Li, Mingyi Chen, Cong Li, 2023, Journal of virology.

Severe fever with thrombocytopenia syndrome phlebovirus non-structural protein activates TPL2 signalling pathway for viral immunopathogenesis

P. Tsichlis, Jae U. Jung, Su-Jin Park, 2019, Nature Microbiology.

Nasal spray of an IgM‐like ACE2 fusion protein HH‐120 accelerates SARS‐CoV‐2 clearance: A single‐center propensity score‐matched cohort study

Wenhui Li, J. Sui, R. Jin, 2023, Journal of medical virology.

Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus.

T. Greenough, Wenhui Li, M. Farzan, 2003, Nature.

What’s new in the renin-angiotensin system?

T. Greenough, J. Kuhn, Wenhui Li, 2004, Cellular and Molecular Life Sciences CMLS.

Molecular insights into Spindlin1-HBx interplay and its impact on HBV transcription from cccDNA minichromosome

Wenhui Li, Haitao Li, Chao-chao Du, 2023, Nature communications.

An IgM-like inhalable ACE2 fusion protein broadly neutralizes SARS-CoV-2 variants

Xiaozhong Peng, Wenhui Li, M. Farzan, 2023, Nature communications.

PreS1- targeting chimeric antigen receptor T cells diminish HBV infection in liver humanized FRG mice.

Wenhui Li, J. Sui, Wenhui He, 2023, Virology.

Site-specific engineering of chemical functionalities on the surface of live hepatitis D virus.

Peng R. Chen, She Chen, Lin Li, 2013, Angewandte Chemie.

TIM-family Proteins Promote Infection of Multiple Enveloped Viruses through Virion-associated Phosphatidylserine

D. Umetsu, Wenhui Li, M. Farzan, 2013, PLoS pathogens.

A rapid and quantitative assay for measuring neutralizing antibodies of Coxsackievirus B3

Xing Wu, Wenhui Li, Zhenglun Liang, 2016, Journal of Virological Methods.

Human Coronavirus HKU1 Spike Protein Uses O-Acetylated Sialic Acid as an Attachment Receptor Determinant and Employs Hemagglutinin-Esterase Protein as a Receptor-Destroying Enzyme

R. Baric, K. Pyrć, W. Marasco, 2015, Journal of Virology.