R. Yan

发表

Structural basis for the recognition of SARS-CoV-2 by full-length human ACE2

Qiang Zhou, Qiang Zhou, R. Yan, 2020, Science.

A neutralizing human antibody binds to the N-terminal domain of the Spike protein of SARS-CoV-2

Qiang Zhou, Junjie Xu, Ling Fu, 2020, Science.

A potent neutralizing human antibody reveals the N-terminal domain of the Spike protein of SARS-CoV-2 as a site of vulnerability

Qiang Zhou, Xiaohong Song, Jun Zhang, 2020, bioRxiv.

Structure of dimeric full-length human ACE2 in complex with B0AT1

Qiang Zhou, R. Yan, Yuanyuan Zhang, 2020, bioRxiv.

Cryo-EM structure of the human heteromeric amino acid transporter b0,+AT-rBAT

Qiang Zhou, Jianlin Lei, R. Yan, 2020, Science Advances.

AXL Promotes SARS-CoV-2 Infection of Pulmonary and Bronchial Epithelial Cells

Qiang Zhou, R. Yan, Jing Huang, 2020 .

ACE2, B0AT1, and SARS-CoV-2 spike protein: Structural and functional implications

Qiang Zhou, R. Yan, Yuanyuan Zhang, 2022, Current Opinion in Structural Biology.

Structural and functional analysis of an inter-Spike bivalent neutralizing antibody against SARS-CoV-2 variants

Bin Zhou, R. Yan, Yuanyuan Zhang, 2022, iScience.

Neutralization mechanism of a human antibody with pan-coronavirus reactivity including SARS-CoV-2

Jianping Ding, Hongzhou Lu, Lu Lu, 2022, Nature Microbiology.

Novel neutralization mechanism of a human antibody with pan-coronavirus reactivity

Hongzhou Lu, Lu Lu, R. Yan, 2021 .

Structural basis for the recognition of the 2019-nCoV by human ACE2

Qiang Zhou, R. Yan, Yuanyuan Zhang, 2020, bioRxiv.

Structural Basis for the Enhanced Infectivity and Immune Evasion of Omicron Subvariants

R. Yan, Yuanyuan Zhang, Yaning Li, 2022, bioRxiv.

Mechanism of substrate transport and inhibition of the human LAT1-4F2hc amino acid transporter

K. Altmann, Qiang Zhou, J. Gertsch, 2021, Cell discovery.

Cryo-EM structures of recombinant human sodium-potassium pump determined in three different states

R. Yan, Yuanyuan Zhang, X. Chi, 2022, Nature Communications.

Cryo-EM structures of the human sodium-potassium pump revealing the gating mechanism on the cytoplasmic side

R. Yan, Yuanyuan Zhang, Qiang Zhou, 2021 .

A high-throughput fully automatic biosensing platform for efficient COVID-19 detection

Liaoyong Wen, R. Yan, B. Dang, 2022, Biosensors and Bioelectronics.

The structure of erastin-bound xCT–4F2hc complex reveals molecular mechanisms underlying erastin-induced ferroptosis

B. Stockwell, Tingjun Hou, R. Yan, 2022, Cell Research.

Structural basis for the assembly of the DNA polymerase holoenzyme from a monkeypox virus variant

R. Yan, Yaning Li, Yaping Shen, 2022, bioRxiv.

SARS-CoV-2 exacerbates proinflammatory responses in myeloid cells through C-type lectin receptors and Tweety family member 2

M. Diamond, Zhilin Long, P. Cresswell, 2021, Immunity.

Structural basis for catalysis and substrate specificity of human ACAT1

H. Qian, Xin Zhao, N. Yan, 2020, Nature.

Structures of ACE2–SIT1 recognized by Omicron variants of SARS-CoV-2

R. Yan, Yuanyuan Zhang, Yaning Li, 2022, Cell Discovery.

Human SEIPIN Binds Anionic Phospholipids.

H. Qian, N. Yan, R. Yan, 2018, Developmental cell.

Structural basis for bivalent binding and inhibition of SARS-CoV-2 infection by human potent neutralizing antibodies

Linqi Zhang, Qiang Zhou, Xinquan Wang, 2020, Cell Research.

Structural basis for the different states of the spike protein of SARS-CoV-2 in complex with ACE2

Qiang Zhou, R. Yan, Yuanyuan Zhang, 2021, Cell Research.

ACE2, B0AT1, and SARS-CoV-2 spike protein: Structural and functional implications

Qiang Zhou, R. Yan, Yuanyuan Zhang, 2022, Current Opinion in Structural Biology.

ACE2-targeting monoclonal antibody as potent and broad-spectrum coronavirus blocker

R. Yan, Yuanyuan Zhang, Yaning Li, 2020, bioRxiv.

Structural advances in sterol-sensing domain-containing proteins.

H. Qian, Pingping Cao, N. Yan, 2022, Trends in biochemical sciences.

Structural basis for sterol sensing by Scap and Insig.

Chuangye Yan, H. Qian, Pingping Cao, 2021, Cell reports.

Structure of the human LAT1–4F2hc heteromeric amino acid transporter complex

Xin Zhao, Qiang Zhou, Jianlin Lei, 2019, Nature.

Molecular mechanism of pH-dependent substrate transport by an arginine-agmatine antiporter

Yigong Shi, Xi Zhang, R. Yan, 2014, Proceedings of the National Academy of Sciences.

Structural insight into the substrate recognition and transport mechanism of the human LAT2–4F2hc complex

Jianlin Lei, R. Yan, Yaning Li, 2020, Cell Discovery.

Structural insight into the substrate recognition and transport mechanism of the human LAT2–4F2hc complex

Qiang Zhou, Jianlin Lei, R. Yan, 2020, Cell Discovery.

Structural basis for sterol sensing by Scap and Insig

Chuangye Yan, H. Qian, Pingping Cao, 2021, bioRxiv.

Novel sarbecovirus bispecific neutralizing antibodies with exceptional breadth and potency against currently circulating SARS-CoV-2 variants and sarbecoviruses

Jincun Zhao, R. Yan, Yuanyuan Zhang, 2022, Cell discovery.

Engineered Trimeric ACE2 Binds and Locks “Three-up” Spike Protein to Potently Inhibit SARS-CoVs and Mutants

Qiang Zhou, Lu Lu, Wei Xu, 2020, bioRxiv.

A structure of human Scap bound to Insig-2 suggests how their interaction is regulated by sterols

Chuangye Yan, X. Gong, H. Qian, 2021, Science.

Engineered trimeric ACE2 binds viral spike protein and locks it in “Three-up” conformation to potently inhibit SARS-CoV-2 infection

Qiang Zhou, Lu Lu, Shibo Jiang, 2020, Cell research.

Structure of the human LAT1–4F2hc heteromeric amino acid transporter complex

Xin Zhao, Qiang Zhou, Jianlin Lei, 2019, Nature.

Mechanism of substrate transport and inhibition of the human LAT1-4F2hc amino acid transporter

K. Altmann, J. Gertsch, R. Yan, 2021, Cell Discovery.