D. Pickard

发表

Identification of protective and broadly conserved vaccine antigens from the genome of extraintestinal pathogenic Escherichia coli

Rino Rappuoli, Steven Sullivan, Ulrich Dobrindt, 2010, Proceedings of the National Academy of Sciences.

Genomic analysis on broiler-associated Clostridium perfringens strains and exploratory caecal microbiome investigation reveals key factors linked to poultry necrotic enteritis

G. Dougan, D. Pickard, L. Hall, 2019, Animal Microbiome.

A suggested new bacteriophage genus: “Viunalikevirus”

Evelien M. Adriaenssens, I. Connerton, H. Ackermann, 2012, Archives of Virology.

Universal DNA primers amplify bacterial DNA from human fetal membranes and link Fusobacterium nucleatum with prolonged preterm membrane rupture.

G. Dougan, A. Edwards, R. Feldman, 2005, Molecular human reproduction.

A Strand-Specific RNA–Seq Analysis of the Transcriptome of the Typhoid Bacillus Salmonella Typhi

Samuel A. Assefa, K. James, G. Dougan, 2009, PLoS genetics.

Complete genome sequence of a multiple drug resistant Salmonella enterica serovar Typhi CT18

Kim Rutherford, Anders Krogh, Stephen D. Bentley, 2001, Nature.

Comparative genome analysis of Salmonella Enteritidis PT4 and Salmonella Gallinarum 287/91 provides insights into evolutionary and host adaptation pathways.

Georgios S. Vernikos, Julian Parkhill, Michael A Quail, 2008, Genome research.

Resistance mechanisms and population structure of highly drug resistant Klebsiella in Pakistan during the introduction of the carbapenemase NDM-1

G. Dougan, I. Haq, D. Pickard, 2019, Scientific Reports.

Expression of heterologous antigens in Salmonella Typhimurium vaccine vectors using the in vivo-inducible, SPI-2 promoter, ssaG.

G. Dougan, D. Pickard, Tao Wu, 2004, Vaccine.

Characterization of defined ompR mutants of Salmonella typhi: ompR is involved in the regulation of Vi polysaccharide expression

G. Dougan, D. Maskell, D. Pickard, 1994, Infection and immunity.

Intimin type influences the site of human intestinal mucosal colonisation by enterohaemorrhagic Escherichia coli O157:H7

G. Dougan, D. Pickard, G. Frankel, 2002, Gut.

Clonal analysis of Salmonella-specific effector T cells reveals serovar-specific and cross-reactive T cell responses

G. Dougan, S. Baker, D. Bumann, 2018, Nature Immunology.

Characterisation of a live Salmonella vaccine stably expressing the Mycobacterium tuberculosis Ag85B–ESAT6 fusion protein

S. Clare, G. Dougan, D. Pickard, 2009, Vaccine.

Role of hns in the virulence phenotype of pathogenic salmonellae

G. Dougan, C. Higgins, C. Dorman, 1994, Molecular microbiology.

Comparison of Salmonella enterica Serovars Typhi and Typhimurium Reveals Typhoidal Serovar-Specific Responses to Bile

G. Dougan, M. Ravenhall, D. Pickard, 2017, Infection and Immunity.

Induced Pluripotent Stem Cell Derived Macrophages as a Cellular System to Study Salmonella and Other Pathogens

G. Dougan, F. Powrie, D. Goulding, 2015, PloS one.

of Healthy Volunteers ) Mutations by ssaV Secretion System ( Pathogenicity Island 2 Type III Salmonella and aroC Derivatives Harboring Defined Salmonella enterica Characterization of

Marjan, Immunization., G. Dougan, 2002 .

Safety of live oral Salmonella typhi vaccine strains with deletions in htrA and aroC aroD and immune response in humans

G. Dougan, M. Levine, C. Tacket, 1997, Infection and immunity.

The role of a stress‐response protein in Salmonella typhimurium virulence

I. Charles, G. Dougan, D. Pickard, 1991, Molecular microbiology.

The role of a stress-response protein in bacterial virulence.

I. Charles, G. Dougan, D. Pickard, 1990, Research in microbiology.

A Genome-Wide Knockout Screen in Human Macrophages Identified Host Factors Modulating Salmonella Infection

Erin E. Gill, A. Bradley, Mark Thomas, 2019, mBio.

Mucosal immunisation of murine neonates using whole cell and acellular Pertussis vaccines.

S. Clare, G. Dougan, D. Pickard, 2004, Vaccine.

Phylogenomic analysis of Clostridium perfringens identifies isogenic strains in gastroenteritis outbreaks, and novel virulence-related features

G. Dougan, D. Pickard, L. Hall, 2019, bioRxiv.

Diagnostic host gene signature to accurately distinguish enteric fever from other febrile diseases

D. Pickard, G. Dougan, B. Basnyat, 2018, bioRxiv.

Morphological, genomic and transcriptomic responses of Klebsiella pneumoniae to the last-line antibiotic colistin

Amy K. Cain, Christine J. Boinett, K. Holt, 2018, Scientific Reports.

Functional analysis of Salmonella Typhi adaptation to survival in water

Gemma C. Langridge, G. Dougan, D. Pickard, 2018, Environmental microbiology.

Construction and characterization of vaccine strains of Salmonella harboring mutations in two different aro genes.

G. Dougan, D. Maskell, D. Pickard, 1988, The Journal of infectious diseases.

Citrobacter rodentium is an Unstable Pathogen Showing Evidence of Significant Genomic Flux

Thomas M. Keane, Nicola K. Petty, S. Nair, 2011, PLoS pathogens.

Construction of a genetically defined Salmonella typhi Ty2 aroA, aroC mutant for the engineering of a candidate oral typhoid-tetanus vaccine.

I. Charles, N. Fairweather, G. Dougan, 1992, Vaccine.

Salmonella typhi and S typhimurium derivatives harbouring deletions in aromatic biosynthesis and Salmonella Pathogenicity Island-2 (SPI-2) genes as vaccines and vectors.

G. Dougan, D. Pickard, Tao Wu, 2003, Vaccine.

Use of the nirB Promoter to Direct the Stable Expression of Heterologous Antigens in Salmonella Oral Vaccine Strains: Development of a Single–Dose Oral Tetanus Vaccine

I. Charles, N. Fairweather, G. Dougan, 1992, Bio/Technology.

The immune responses to bacterial antigens encountered in vivo at mucosal surfaces.

S. Clare, G. Dougan, S. Dunstan, 2000, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.

Stable expression of foreign antigens from the chromosome of Salmonella typhimurium vaccine strains.

N. Fairweather, G. Dougan, D. Maskell, 1990, Gene.

The golden death bacillus Chryseobacterium nematophagum is a novel matrix digesting pathogen of nematodes

M. Félix, D. Pickard, W. Weir, 2019, BMC biology.

Characterization of a ViI-like Phage Specific to Escherichia coli O157:H7

H. Ackermann, H. Anany, A. Villegas, 2011, Virology Journal.

Isolation of stable aroA mutants of Salmonella typhi Ty2: Properties and preliminary characterisation in mice

G. Dougan, D. Maskell, D. Pickard, 1987, Molecular and General Genetics MGG.

Global Phylogeny of Shigella sonnei Strains from Limited Single Nucleotide Polymorphisms (SNPs) and Development of a Rapid and Cost-Effective SNP-Typing Scheme for Strain Identification by High-Resolution Melting Analysis

K. Holt, J. Parkhill, F. Weill, 2012, Journal of Clinical Microbiology.

The Accessory Genome of Shiga Toxin-Producing Escherichia coli Defines a Persistent Colonization Type in Cattle

L. Geue, C. Berens, L. Wieler, 2016, Applied and Environmental Microbiology.

Genomic and Phenotypic Analyses Reveal the Emergence of an Atypical Salmonella enterica Serovar Senftenberg Variant in China

A. Pain, H. Ansari, D. Pickard, 2016, Journal of Clinical Microbiology.

Genome Sequence of Porcine Escherichia coli Strain IMT8073, an Atypical Enteropathogenic E. coli Strain Isolated from a Piglet with Diarrhea

G. Dougan, L. Wieler, D. Pickard, 2013, Genome Announcements.

A Second Large Plasmid Encodes Conjugative Transfer and Antimicrobial Resistance in O119:H2 and Some Typical O111 Enteropathogenic Escherichia coli Strains

I. Okeke, D. Pickard, A. Nwaneshiudu, 2007, Journal of bacteriology.

Microevolution of epidemiological highly relevant non-O157 enterohemorrhagic Escherichia coli of serogroups O26 and O111.

A. Mellmann, H. Karch, L. Wieler, 2018, International Journal of Medical Microbiology.

Comparison of Salmonella enterica serovars Typhi and Typhimurium reveals typhoidal- 1 specific responses to bile 2

G. Dougan, M. Ravenhall, D. Pickard, 2017 .

Transposon Insertion Sequencing Elucidates Novel Gene Involvement in Susceptibility and Resistance to Phages T4 and T7 in Escherichia coli O157

Amy K. Cain, Christine J. Boinett, T. Dallman, 2018, mBio.

Isolation of orally attenuated Salmonella typhimurium following TnphoA mutagenesis

G. Dougan, D. Maskell, D. Pickard, 1989, Infection and immunity.

Cloning, nucleotide sequencing, and expression of tetanus toxin fragment C in Escherichia coli

N. Fairweather, D. Pickard, R. Thomson, 1986, Journal of bacteriology.

Rapid transcriptional responses to serum exposure are associated with sensitivity and resistance to antibody-mediated complement killing in invasive Salmonella Typhimurium ST313

G. Dougan, D. Pickard, R. Kingsley, 2019, Wellcome open research.

Insertions in the OCL1 locus of Acinetobacter baumannii lead to shortened lipooligosaccharides

G. Dougan, K. Holt, D. Pickard, 2014, Research in microbiology.

Evaluation of Salmonella typhimurium strains harbouring defined mutations in htrA and aroA in the murine salmonellosis model.

I. Charles, G. Dougan, D. Pickard, 1992, Microbial pathogenesis.

High-throughput transposon mutagenesis in the family Enterobacteriaceae reveals core essential genes and rapid turnover of essentiality

Amy K. Cain, Christine J. Boinett, Gemma C. Langridge, 2022, bioRxiv.

Signatures of Adaptation in Human Invasive Salmonella Typhimurium ST313 Populations from Sub-Saharan Africa

S. Clare, G. Dougan, J. Parkhill, 2015, PLoS neglected tropical diseases.

Molecular cloning and characterization of protective outer membrane protein P . 69 from Bordetella pertussis 1

N. Fairweather, D. Pickard, P. Morrissey, 2003 .

First report and whole-genome sequencing of Pseudochrobactrum saccharolyticum in Latin America.

J. Foster, V. Azevedo, D. Pickard, 2022, Microbes and infection.

Correction: Signatures of Adaptation in Human Invasive Salmonella Typhimurium ST313 Populations from Sub-Saharan Africa

S. Clare, G. Dougan, J. Parkhill, 2015, PLoS neglected tropical diseases.

Molecular cloning and analysis of P. 69, a vir-controlled protein from Bordetella pertussis.

I. Charles, N. Fairweather, G. Dougan, 1988, The Tokai journal of experimental and clinical medicine.

Candidate Live, Attenuated Salmonella enterica Serotype Typhimurium Vaccines with Reduced Fecal Shedding Are Immunogenic and Effective Oral Vaccines

S. Clare, G. Dougan, A. Jansen, 2007, Infection and Immunity.

ESBL-plasmid carriage in E. coli enhances in vitro bacterial competition fitness and serum resistance in some strains of pandemic sequence types without overall fitness cost

N. Ahmed, K. Tedin, L. Wieler, 2018, Gut Pathogens.

Development of Attenuated Salmonella Strains that Express Heterologous Antigens.

D. Pickard, G. Dougan, L. P. Londoño, 1996, Methods in Molecular Medicine.

Mobilization of the incQ Plasmid R300B with a Chromosomal Conjugation System in Salmonella enterica Serovar Typhi

J. Farrar, G. Dougan, S. Whitehead, 2008, Journal of bacteriology.

Salmonella Paratyphi A Outer Membrane Vesicles Displaying Vi Polysaccharide as a Multivalent Vaccine against Enteric Fever

F. Mancini, D. Pickard, F. Necchi, 2020, Infection and Immunity.

Edinburgh Explorer Transposon Insertion Sequencing Elucidates Novel Gene Involvement in Susceptibility and Resistance to Phages T4 and T7 in O157

Christine J. Boinett, T. Dallman, J. Parkhill, 2018 .

contributing to Vi capsular expression in Salmonella Typhi 3

Gemma C. Langridge, Karthikeyan., G. Dougan, 2013 .

Salmonella Typhi sense host neuroendocrine stress hormones and release the toxin haemolysin E

G. Dougan, A. Ivens, S. Baker, 2011, EMBO reports.

The Clostridium difficile spo0A Gene Is a Persistence and Transmission Factor

N. Fairweather, S. Clare, G. Dougan, 2012, Infection and Immunity.

Evaluation of a novel Vi conjugate vaccine in a murine model of salmonellosis.

S. Clare, G. Dougan, D. Pickard, 2006, Vaccine.

Molecular Characterization of the viaB Locus Encoding the Biosynthetic Machinery for Vi Capsule Formation in Salmonella Typhi

G. Dougan, D. Goulding, D. Pickard, 2012, PloS one.

Emergence and global spread of epidemic healthcare-associated Clostridium difficile

M. Pirmohamed, G. Dougan, J. Parkhill, 2012, Nature Genetics.

Genome sequencing of disease and carriage isolates of nontypeable Haemophilus influenzae identifies discrete population structure

Claudio Donati, Rino Rappuoli, Matteo De Chiara, 2014, Proceedings of the National Academy of Sciences.

Genomic and Functional Analysis of Emerging Virulent and Multidrug-Resistant Escherichia coli Lineage Sequence Type 648

J. Corander, S. Fuchs, G. Peirano, 2019, Antimicrobial Agents and Chemotherapy.

Carriage of Extended-Spectrum Beta-Lactamase-Plasmids Does Not Reduce Fitness but Enhances Virulence in Some Strains of Pandemic E. coli Lineages

L. Wieler, C. Ewers, D. Pickard, 2016, Front. Microbiol..

The neglected role of antibody in protection against bacteremia caused by nontyphoidal strains of Salmonella in African children.

G. Dougan, N. Thomson, M. Molyneux, 2008, The Journal of clinical investigation.

Meticillin-resistant Staphylococcus aureus with a novel mecA homologue in human and bovine populations in the UK and Denmark: a descriptive study

Julian Parkhill, Stephen D Bentley, Sharon J Peacock, 2011, The Lancet. Infectious diseases.

Azole-resistant Aspergillus fumigatus with the environmental TR46/Y121F/ T289A mutation in India

G. Dougan, K. Holt, D. Pickard, 2014 .

Genomic analysis on broiler-associated Clostridium perfringens strains and caecal microbiome profiling reveals key factors linked to poultry Necrotic Enteritis

G. Dougan, D. Pickard, L. Hall, 2019, bioRxiv.

Phospholipase C and haemolytic activities of Clostridium perfringens alpha‐toxin cloned in Escherichia coli: sequence and homology with a Baciilus cereus phospholipase C

N. Fairweather, G. Dougan, D. Pickard, 1989, Molecular microbiology.

First Report of Human Infection with Salmonella enterica Serovar Apapa Resulting from Exposure to a Pet Lizard

D. Pickard, M. Farrington, E. Threlfall, 2009, Journal of Clinical Microbiology.

Phylogeographical analysis of the dominant multidrug-resistant H58 clade of Salmonella Typhi identifies inter- and intracontinental transmission events

Paul Turner, Julian Parkhill, Jacqueline A. Keane, 2015, Nature Genetics.

Inhibitory Concentrations of Ciprofloxacin Induce an Adaptive Response Promoting the Intracellular Survival of Salmonella enterica Serovar Typhimurium

G. Dougan, S. Baker, N. Thomson, 2021, mBio.

Inhibitory concentrations of ciprofloxacin induce an adaptive response promoting the intracellular survival of Salmonella Typhimurium

G. Dougan, S. Baker, N. Thomson, 2021, bioRxiv.

Inhibitory Concentrations of Ciprofloxacin Induce an Adaptive Response Promoting the Intracellular Survival of Salmonella enterica Serovar Typhimurium

G. Dougan, N. Thomson, D. Pickard, 2021 .

A Conserved Acetyl Esterase Domain Targets Diverse Bacteriophages to the Vi Capsular Receptor of Salmonella enterica Serovar Typhi

Nicola K. Petty, Andries J. van Tonder, B. Barrell, 2010, Journal of bacteriology.

Exploiting induced pluripotent stem cell-derived macrophages to unravel host factors influencing Chlamydia trachomatis pathogenesis

Nick Thomson, Erin E. Gill, Robert E W Hancock, 2017, Nature Communications.

Interaction of Salmonella enterica Serovar Typhimurium with Intestinal Organoids Derived from Human Induced Pluripotent Stem Cells

G. Dougan, D. Goulding, L. Vallier, 2015, Infection and Immunity.

Genomic Analysis of Clostridium perfringens BEC/CPILE-Positive, Toxinotype D and E Strains Isolated from Healthy Children

D. Pickard, J. Kroll, L. Hall, 2019, Toxins.

Five decades of genome evolution in the globally distributed, extensively antibiotic-resistant Acinetobacter baumannii global clone 1

Mark B. Schultz, G. Dougan, K. Holt, 2016, Microbial genomics.

Characterization of Candidate Live Oral Salmonella typhi Vaccine Strains Harboring Defined Mutations inaroA, aroC, and htrA

G. Dougan, M. Kagnoff, L. Eckmann, 1999, Infection and Immunity.

Long-read-sequenced reference genomes of the seven major lineages of enterotoxigenic Escherichia coli (ETEC) circulating in modern time

Christine J. Boinett, G. Dougan, D. Pickard, 2020, Scientific Reports.

An African Salmonella Typhimurium ST313 sublineage with extensive drug-resistance and signatures of host adaptation

Jan Jacobs, Sushmita Sridhar, Gordon Dougan, 2019, Nature Communications.

Molecular Characterization of the Salmonella enterica Serovar Typhi Vi-Typing Bacteriophage E1

J. Wain, G. Dougan, N. Hamlin, 2008, Journal of bacteriology.

Identification and characterization of a protective immunodominant B cell epitope of pertactin (P.69) from Bordetella pertussis

I. Charles, N. Fairweather, G. Dougan, 1991, European journal of immunology.

Resistance mechanisms and population structure of highly drug resistant Klebsiella in Pakistan during the introduction of the carbapenemase NDM-1

G. Dougan, I. Haq, D. Pickard, 2019, Scientific Reports.

Characterization of the yehUT Two-Component Regulatory System of Salmonella enterica Serovar Typhi and Typhimurium

Andrew J. Page, G. Dougan, K. Holt, 2013, PloS one.

Structure, Diversity, and Mobility of the Salmonella Pathogenicity Island 7 Family of Integrative and Conjugative Elements within Enterobacteriaceae

M. Quail, G. Dougan, C. Churcher, 2012, Journal of bacteriology.

A novel ciprofloxacin-resistant subclade of H58 Salmonella Typhi is associated with fluoroquinolone treatment failure

G. Dougan, K. Holt, S. Baker, 2016, eLife.

Genome-Based Infection Tracking Reveals Dynamics of Clostridium difficile Transmission and Disease Recurrence

M. Pirmohamed, G. Dougan, J. Parkhill, 2015, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Phylogenetic Analysis Indicates a Longer Term Presence of the Globally Distributed H58 Haplotype of Salmonella Typhi in Southern India

G. Kang, G. Dougan, D. Pickard, 2020, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

An extended genotyping framework for Salmonella enterica serovar Typhi, the cause of human typhoid

Jacqueline A. Keane, Richard Holliman, Thomas R Connor, 2016, Nature Communications.

The Molecular and Spatial Epidemiology of Typhoid Fever in Rural Cambodia

G. Dougan, K. Holt, S. Baker, 2016, PLoS neglected tropical diseases.

Molecular Surveillance Identifies Multiple Transmissions of Typhoid in West Africa

S. Nair, G. Dougan, K. Holt, 2016, PLoS neglected tropical diseases.

Phylogenomic analysis of gastroenteritis-associated Clostridium perfringens in England and Wales over a 7-year period indicates distribution of clonal toxigenic strains in multiple outbreaks and extensive involvement of enterotoxin-encoding (CPE) plasmids

G. Dougan, D. Pickard, L. Hall, 2019, Microbial Genomics.

Clostridium perfringens identifies isogenic strains in gastroenteritis 2 outbreaks , and novel virulence-related features 3 Running title : Gastroenteritis-associated Clostridium perfringens 4 5 Author information 6 Affiliations 7

G. Dougan, D. Pickard, L. Hall, 2019 .

Gut inflammation can boost horizontal gene transfer between pathogenic and commensal Enterobacteriaceae

Wolf-Dietrich Hardt, Bärbel Stecher, Martin Ackermann, 2012, Proceedings of the National Academy of Sciences.

Characterization of the Genomes of a Diverse Collection of Salmonella enterica Serovar Typhimurium Definitive Phage Type 104

J. Wain, G. Dougan, A. Ivens, 2008, Journal of bacteriology.

Preparation of bacteriophage lysates and pure DNA.

D. Pickard, 2009, Methods in molecular biology.

Isolation, characterization and nucleotide sequences of the aroC genes encoding chorismate synthase from Salmonella typhi and Escherichia coli.

I. Charles, G. Dougan, A. Hawkins, 1990, Journal of general microbiology.

A suggested new bacteriophage genus: “Viunalikevirus”

Evelien M. Adriaenssens, I. Connerton, H. Ackermann, 2012, Archives of Virology.

Dissemination and pathogenesis of toxigenic Clostridium perfringens strains linked to neonatal intensive care units and Necrotising Enterocolitis

P. Clarke, G. Dougan, D. Pickard, 2021, bioRxiv.

Sequencing and functional annotation of avian pathogenic Escherichia coli serogroup O78 strains reveals the evolution of E. coli lineages pathogenic for poultry via distinct mechanisms

Gemma C. Langridge, Roy R. Chaudhuri, Thomas R. Connor, 2013 .

Shigella sonnei genome sequencing and phylogenetic analysis indicate recent global dissemination from Europe

D. W. Kim, E. Holmes, J. Farrar, 2012, Nature Genetics.

Genomic surveillance of Escherichia coli ST131 identifies local expansion and serial replacement of subclones

J. Parkhill, T. Downing, D. Pickard, 2019, bioRxiv.

Molecular and physiological analysis of three Pseudomonas aeruginosa phages belonging to the “N4-like viruses”

G. Dougan, D. Goulding, Matthew Lewis, 2010, Virology.

Preterm Infant-Associated Clostridium tertium, Clostridium cadaveris, and Clostridium paraputrificum Strains: Genomic and Evolutionary Insights

P. Clarke, G. Dougan, D. Pickard, 2017, Genome biology and evolution.

Genome placement of alpha-haemolysin cluster is associated with alpha-haemolysin sequence variation, adhesin and iron acquisition factor profile of Escherichia coli

D. Pickard, P. Schierack, Michał Burdukiewicz, 2021, Microbial genomics.

Identification of a novel type IV pilus gene cluster required for gastrointestinal colonization of Citrobacter rodentium

G. Dougan, D. Pickard, C. Simmons, 2003, Molecular microbiology.

Proteomic and Genomic Characterization of Highly Infectious Clostridium difficile 630 Spores

S. Clare, G. Dougan, J. Parkhill, 2009, Journal of bacteriology.

Effects of immune colostrum on the expression of a K88 plasmid encoded determinant: role of plasmid stability and influence of phenotypic expression of K88 fimbriae.

G. Dougan, D. Pickard, L. K. Nagy, 1986, Journal of general microbiology.

The role of prophage-like elements in the diversity of Salmonella enterica serovars.

J. Wain, G. Dougan, A. Ivens, 2004, Journal of molecular biology.

Composition, Acquisition, and Distribution of the Vi Exopolysaccharide-Encoding Salmonella enterica Pathogenicity Island SPI-7

J. Wain, M. Quail, G. Dougan, 2003, Journal of bacteriology.

A Genomewide Mutagenesis Screen Identifies Multiple Genes Contributing to Vi Capsular Expression in Salmonella enterica Serovar Typhi

Gemma C. Langridge, Gordon Dougan, Robert A. Kingsley, 2013, Journal of bacteriology.

Mechanistic Insights into the Capsule-Targeting Depolymerase from a Klebsiella pneumoniae Bacteriophage

G. Dougan, T. Lithgow, D. Pickard, 2021, Microbiology spectrum.

Identification of Natural Mutations Responsible for Altered Infection Phenotypes of Salmonella enterica Clinical Isolates by Using Cell Line Infection Screens

K. Tedin, D. Pickard, P. Schierack, 2020, Applied and Environmental Microbiology.

Construction and characterization of Bordetella pertussis mutants lacking the vir‐regulated P.69 outer membrane protein

N. Fairweather, G. Dougan, E. Hewlett, 1991, Molecular microbiology.

Targeted Restoration of the Intestinal Microbiota with a Simple, Defined Bacteriotherapy Resolves Relapsing Clostridium difficile Disease in Mice

Taane G. Clark, Julian Parkhill, Roland Rad, 2012, PLoS pathogens.

Emergence of carbapenem, beta-lactamase inhibitor and cefoxitin resistant lineages from a background of ESBL-producing Klebsiella pneumoniae and K. quasipneumoniae highlights different evolutionary mechanisms

Josefin Bartholdson Scott, G. Dougan, D. Pickard, 2018, bioRxiv.

Identification of enterotoxigenic Escherichia coli (ETEC) clades with long-term global distribution

J. Corander, G. Dougan, D. Rasko, 2014, Nature Genetics.

A conjugative plasmid carrying the carbapenem resistance gene blaOXA-23 in AbaR4 in an extensively resistant GC1 Acinetobacter baumannii isolate.

K. Holt, D. Pickard, M. Hamidian, 2014, The Journal of antimicrobial chemotherapy.

Immunological relationship between delta-hemolysins of Staphylococcus aureus and coagulase-negative strains of staphylococci

D. Pickard, W. Turner, 1979, Infection and immunity.

Comparison of Abilities of Salmonella enterica Serovar Typhimurium aroA aroD and aroA htrA Mutants To Act as Live Vectors

D. Pickard, M. Roberts, S. Chatfield, 2000, Infection and Immunity.

Evolution of atypical enteropathogenic E. coli by repeated acquisition of LEE pathogenicity island variants

David J. Edwards, G. Dougan, K. Holt, 2016, Nature Microbiology.

A Phylogenetic and Phenotypic Analysis of Salmonella enterica Serovar Weltevreden, an Emerging Agent of Diarrheal Disease in Tropical Regions

A. Brisabois, S. Clare, G. Dougan, 2016, PLoS neglected tropical diseases.

High-Resolution Genotyping of the Endemic Salmonella Typhi Population during a Vi (Typhoid) Vaccination Trial in Kolkata

G. Dougan, K. Holt, D. Pickard, 2012, PLoS neglected tropical diseases.

the Vi capsular receptor of Salmonella enterica serovar Typhi 2

Nicola K. Petty, B. Barrell, G. Dougan, 2010 .

The architecture and stabilisation of flagellotropic tailed bacteriophages

G. Dougan, T. Lithgow, H. Venugopal, 2020, Nature Communications.

The flagellotropic bacteriophage YSD1 targets Salmonella Typhi with a Chi‐like protein tail fibre

S. Clare, G. Dougan, T. Lithgow, 2019, Molecular microbiology.

Retrospective Application of Transposon-Directed Insertion Site Sequencing to a Library of Signature-Tagged Mini-Tn5Km2 Mutants of Escherichia coli O157:H7 Screened in Cattle

Gemma C. Langridge, Roy R. Chaudhuri, D. Turner, 2011, Journal of bacteriology.

Acquisition of virulence-associated factors by the enteric pathogens Escherichia coli and Salmonella enterica.

J. Wain, G. Dougan, D. Pickard, 2001, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.

Analysis of the Hypervariable Region of the Salmonella enterica Genome Associated with tRNAleuX

J. Farrar, G. Dougan, A. Ivens, 2005, Journal of bacteriology.

Morphological, genomic and transcriptomic responses of Klebsiella pneumoniae to the last-line antibiotic colistin

Amy K. Cain, Christine J. Boinett, K. Holt, 2018, Scientific Reports.

A novel prophage identified in strains from Salmonella enterica serovar Enteritidis is a phylogenetic signature of the lineage ST-1974

D. Pickard, A. Iriarte, J. Chabalgoity, 2018, Microbial genomics.

The lrp Gene and Its Role in Type I Fimbriation in Citrobacter rodentium

G. Dougan, D. Pickard, M. De Felice, 2005, Journal of bacteriology.

Draft Genome Sequence of Highly Nematicidal Bacillus thuringiensis DB27

R. Sommer, G. Dougan, Craig Corton, 2014, Genome Announcements.

A new haemolysin from Staphylococcus aureus which lyses horse erythrocytes.

D. Pickard, W. Turner, Kent Br, 1980, Journal of general microbiology.

Identification of a marker for two lineages within the GC1 clone of Acinetobacter baumannii

G. Dougan, K. Holt, D. Pickard, 2013, The Journal of antimicrobial chemotherapy.

Carbapenem and amikacin resistance on a large conjugative Acinetobacter baumannii plasmid

K. Holt, D. Pickard, R. Hall, 2014, The Journal of antimicrobial chemotherapy.

Molecular cloning and characterization of protective outer membrane protein P.69 from Bordetella pertussis.

I. Charles, N. Fairweather, G. Dougan, 1989, Proceedings of the National Academy of Sciences of the United States of America.

Genome Sequence of Acinetobacter baumannii Strain A1, an Early Example of Antibiotic-Resistant Global Clone 1

K. Holt, D. Pickard, J. Hawkey, 2015, Genome Announcements.

A small Acinetobacter plasmid carrying the tet39 tetracycline resistance determinant

K. Holt, D. Pickard, M. Hamidian, 2015, The Journal of antimicrobial chemotherapy.

A GC1 Acinetobacter baumannii isolate carrying AbaR3 and the aminoglycoside resistance transposon TnaphA6 in a conjugative plasmid

G. Dougan, K. Holt, D. Pickard, 2013, The Journal of antimicrobial chemotherapy.

An O Antigen Capsule Modulates Bacterial Pathogenesis in Shigella sonnei

G. Dougan, N. Thomson, P. Sansonetti, 2015, PLoS pathogens.

Comparative genomics of Salmonella enterica serovar Enteritidis ST-11 isolated in Uruguay reveals lineages associated with particular epidemiological traits

D. Pickard, A. Iriarte, J. Chabalgoity, 2020, Scientific Reports.

Yersinia pestis pFra Shows Biovar-Specific Differences and Recent Common Ancestry with aSalmonella enterica Serovar Typhi Plasmid

Julian Parkhill, Richard W. Titball, Karen L. Mungall, 2001, Journal of bacteriology.

Molecular cloning and characterization of the aroD gene encoding 3-dehydroquinase from Salmonella typhi.

I. Charles, N. Fairweather, G. Dougan, 1991, Journal of general microbiology.

Genomic insights into the diversity, virulence and resistance of Klebsiella pneumoniae extensively drug resistant clinical isolates

O. Franco, W. F. Porto, S. C. Dias, 2021, Microbial genomics.

Expression of the Bordetella pertussis P.69 pertactin adhesin in Escherichia coli: fate of the carboxy-terminal domain.

I. Charles, N. Fairweather, G. Dougan, 1994, Microbiology.

Drug Resistance in Salmonella enterica ser. Typhimurium Bloodstream Infection, Malawi

Amy K. Cain, G. Dougan, M. Aslett, 2014, Emerging infectious diseases.

Multiplex PCR assay to detect high risk lineages of Salmonella Typhi and Paratyphi A

G. Dougan, D. Pickard, M. Holmes, 2021, medRxiv.

Particular genomic and virulence traits associated with preterm infant-derived toxigenic Clostridium perfringens strains

G. Dougan, D. Pickard, L. Hall, 2023, Nature Microbiology.

The Escherichia coli gene pool.

J. Wain, G. Dougan, D. Pickard, 2001, Current opinion in microbiology.

Lysogenic conversion of atypical enteropathogenic Escherichia coli (aEPEC) from human, murine, and bovine origin with bacteriophage Φ3538 Δstx2::cat proves their enterohemorrhagic E. coli (EHEC) progeny.

H. Karch, D. Goulding, L. Wieler, 2018, International journal of medical microbiology : IJMM.

A novel method for increasing bacterial cellular yields of a fimbrial subunit polypeptide

G. Dougan, D. Pickard, M. Winther, 1985 .

Characterisation and distribution of a cryptic Salmonella typhi plasmid pHCM2.

Julian Parkhill, Gordon Dougan, Jeremy Farrar, 2002, Plasmid.

Evidence for Contemporary Switching of the O-Antigen Gene Cluster between Shiga Toxin-Producing Escherichia coli Strains Colonizing Cattle

L. Geue, C. Berens, L. Wieler, 2017, Front. Microbiol..

Epitopes in the capsular polysaccharide and the porin OmpK36 receptors are required for bacteriophage infection of Klebsiella pneumoniae.

G. Dougan, T. Lithgow, D. Pickard, 2023, Cell reports.

Diagnostic host gene signature for distinguishing enteric fever from other febrile diseases

G. Dougan, S. Baker, A. Pollard, 2019, EMBO molecular medicine.

Clonal analysis of Salmonella-specific effector T cells reveals serovar-specific and cross-reactive T cell responses

G. Dougan, S. Baker, D. Bumann, 2018, Nature Immunology.

Meticillin-resistant Staphylococcus aureus with a novel mecA homologue in human and bovine populations in the UK and Denmark: a descriptive study

K. Brooks, J. Parkhill, D. Maskell, 2011, The Lancet. Infectious diseases.

Drug Resistance in Salmonella enterica ser. Typhimurium Bloodstream Infection, Malawi

Amy K. Cain, G. Dougan, M. Aslett, 2014, Emerging infectious diseases.

Characterisation of Bacteriophage-Encoded Depolymerases Selective for Key Klebsiella pneumoniae Capsular Exopolysaccharides

N. Thomson, D. Pickard, M. Enright, 2021, Frontiers in Cellular and Infection Microbiology.

The emergence and intercontinental spread of a multidrug-resistant clade of typhoid agent Salmonella enterica serovar Typhi

G. Dougan, K. Holt, S. Baker, 2016, The Lancet.

Sequencing and Functional Annotation of Avian Pathogenic Escherichia coli Serogroup O78 Strains Reveal the Evolution of E. coli Lineages Pathogenic for Poultry via Distinct Mechanisms

G. Dougan, N. Thomson, R. Chaudhuri, 2012, Infection and Immunity.

Edinburgh Research Explorer Sequencing and functional annotation of avian pathogenic Escherichia coli serogroup O78 strains reveals the evolution of E. coli lineages pathogenic for poultry via distinct mechanisms

G. Dougan, N. Thomson, R. Chaudhuri, 2017 .

Edinburgh Research Explorer Sequencing and functional annotation of avian pathogenic Escherichia coli serogroup O78 strains reveals the evolution of E. coli lineages pathogenic for poultry via distinct mechanisms

G. Dougan, N. Thomson, R. Chaudhuri, 2013 .

Genomic investigation of antimicrobial resistance in Brucella abortus strains isolated from cattle in Brazil

J. Foster, D. Pickard, J. Gillece, 2023, Gene Reports.

Edinburgh Research Explorer Transposon Insertion Sequencing Elucidates Novel Gene Involvement in Susceptibility and Resistance to Phages T4 and T7 in O157

Christine J. Boinett, T. Dallman, J. Parkhill, 2018 .

Rapid transcriptional responses to serum exposure are associated with sensitivity and resistance to antibody- mediated complement killing in invasive Salmonella Typhimurium ST313 [version 1; peer review: 2 approved]

G. Dougan, D. Pickard, R. Kingsley, 2020 .

Comparative genome analysis of Salmonella Enteritidis PT4 and Salmonella Gallinarum 287/91 provides insights into evolutionary and host adaptation pathways.

Georgios S. Vernikos, A. Bignell, M. Quail, 2008, Genome research.

Genetic Analysis of Toxin Determinants of Clostridium Perfringens

N. Fairweather, G. Dougan, D. Pickard, 1987 .

Retrospective Application of Transposon-Directed Insertion Site Sequencing to a Library of Signature-Tagged Mini-Tn5Km2 Mutants of Escherichia coli O157:H7 Screened in Cattle

D. Turner, D. Maskell, N. Thomson, 2011, Journal of bacteriology.

Genome sequencing of disease and carriage isolates of nontypeable Haemophilus influenzae identifies discrete population structure

G. Dougan, C. Donati, R. Rappuoli, 2014, Proceedings of the National Academy of Sciences.

Evaluation of applicability of DNA microarray–based characterization of bovine Shiga toxin–producing Escherichia coli isolates using whole genome sequence analysis

L. Geue, D. Pickard, T. Semmler, 2017, Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc.