S. Abrams

S. Abrams, Colleen S Netherby, Michelle N. Messmer, 2016, Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research.

IFN Regulatory Factor 8 Represses GM-CSF Expression in T Cells To Affect Myeloid Cell Lineage Differentiation

M. Merad, Chen-feng Qi, K. Ozato, 2015, The Journal of Immunology.

Targeting myeloid cells in the tumor microenvironment enhances vaccine efficacy in murine epithelial ovarian cancer

L. Ylagan, K. Odunsi, K. Moysich, 2015, Oncotarget.

Tumor-Induced STAT3 Signaling in Myeloid Cells Impairs Dendritic Cell Generation by Decreasing PKCβII Abundance

L. Carlson, Kelvin P Lee, S. Abrams, 2014, Science Signaling.

Myeloid-derived suppressor cell development is regulated by a STAT/IRF-8 axis.

Q. Hu, Song Liu, Austin Miller, 2013, The Journal of clinical investigation.

Myeloid-Derived Suppressor Cells Modulate Immune Responses Independently of NADPH Oxidase in the Ovarian Tumor Microenvironment in Mice

K. Odunsi, S. Abrams, B. Segal, 2013, PloS one.

β-Adrenergic Signaling in Mice Housed at Standard Temperatures Suppresses an Effector Phenotype in CD8+ T Cells and Undermines Checkpoint Inhibitor Therapy.

B. Hylander, E. Repasky, K. Attwood, 2017, Cancer research.

A Call for Epidemiological Research on Myeloid-Derived Suppressor Cells in Ovarian Cancer: A Review of the Existing Immunological Evidence and Suggestions for Moving Forward

K. Moysich, S. Abrams, A. Stenzel, 2019, Front. Immunol..

Generation of a C57BL/6 MYC‐Driven Mouse Model and Cell Line of Prostate Cancer

L. Ellis, D. Goodrich, G. Azabdaftari, 2016, The Prostate.

Regulation of the Interferon regulatory factor-8 (IRF-8) Tumor Suppressor Gene by the Signal Transducer and Activator of Transcription 5 (STAT5) Transcription Factor in Chronic Myeloid Leukemia*

S. Abrams, J. Waight, E. Griffiths, 2014, The Journal of Biological Chemistry.

Identification of a ras oncogene peptide that contains both CD4(+) and CD8(+) T cell epitopes in a nested configuration and elicits both T cell subset responses by peptide or DNA immunization.

J. Bristol, S. Abrams, P. Lindinger, 2000, Cellular immunology.

Generation of stable CD4+ and CD8+ T cell lines from patients immunized with ras oncogene-derived peptides reflecting codon 12 mutations.

J. Schlom, E. Bergmann-Leitner, S. Abrams, 1997, Cellular immunology.

Peptide‐specific activation of cytolytic CD4+ T lymphocytes against tumor cells bearing mutated epitopes of K‐ras p21

J. Schlom, D. Wells, S. Abrams, 1995, European journal of immunology.

Identification of a G-CSF-Granulocytic MDSC axis that promotes tumor progression

S. Abrams, J. Waight, 2012, Oncoimmunology.

Loss-of-function of the hippo transducer TAZ reduces mammary tumor growth through a myeloid-derived suppressor cell-dependent mechanism

He Shen, C. Frangou, Jianmin Zhang, 2022, Cancer Gene Therapy.

VSSP abrogates murine ovarian tumor-associated myeloid cell-driven immune suppression and induces M1 polarization in tumor-associated macrophages from ovarian cancer patients

K. Odunsi, K. Eng, Kelvin P Lee, 2022, Cancer Immunology, Immunotherapy.

Differential Role of Fas/Fas Ligand Interactions in Cytolysis of Primary and Metastatic Colon Carcinoma Cell Lines by Human Antigen-Specific CD8+ CTL

E. Bergmann-Leitner, S. Abrams, 2000, Journal of Immunology.

An osteopontin/CD44 immune checkpoint controls CD8+ T cell activation and tumor immune evasion

K. Ozato, Dafeng Yang, Kebin Liu, 2018, The Journal of clinical investigation.

The Granulocyte Progenitor Stage Is a Key Target of IRF8-Mediated Regulation of Myeloid-Derived Suppressor Cell Production

Austin Miller, S. Abrams, Colleen S Netherby, 2017, The Journal of Immunology.

Vaccines and Immunostimulants

J. Schlom, S. Abrams, 2003 .

Sensitivity of T cells to anti‐CD3‐stimulated suicide is independent of functional phenotype

J. Russell, S. Abrams, Ruduan Wang, 1992, European journal of immunology.

Antitumor activity and immune responses induced by a recombinant carcinoembryonic antigen-vaccinia virus vaccine.

J. Schlom, K. Irvine, S. Abrams, 1992, Journal of the National Cancer Institute.

Modulating the Expression of IFN Regulatory Factor 8 Alters the Protumorigenic Behavior of CD11b+Gr-1+ Myeloid Cells1

S. Steinberg, S. Abrams, D. Liewehr, 2009, The Journal of Immunology.

Modulating the expression of IFN regulatory factor 8 alters the protumorigenic behavior of CD11b+Gr-1+ myeloid cells

S. Steinberg, S. Abrams, D. Liewehr, 2009, The Journal of Immunology.

A phase I vaccine trial with peptides reflecting ras oncogene mutations of solid tumors.

J. Schlom, C. Allegra, E. Bergmann-Leitner, 1999, Journal of immunotherapy.

Induction of antitumor immunity by recombinant vaccinia viruses expressing B7-1 or B7-2 costimulatory molecules.

J. Schlom, S. Abrams, J. Kantor, 1994, Cancer research.

Admixture of a recombinant vaccinia virus containing the gene for the costimulatory molecule B7 and a recombinant vaccinia virus containing a tumor-associated antigen gene results in enhanced specific T-cell responses and antitumor immunity.

W. L. Shupert, J. Schlom, S. Abrams, 1995, Cancer research.

Redirecting macrophage function to sustain their "defender" antitumor activity.

S. Abrams, Stephanie L. Tzetzo, 2021, Cancer cell.

Immune response to a carcinoembryonic antigen polynucleotide vaccine.

J. Schlom, D. Curiel, F. Loechel, 1994, Cancer research.

Interferon regulatory factor-8 modulates the development of tumour-induced CD11b+Gr-1+ myeloid cells

S. Steinberg, J. Reid, Kebin Liu, 2009, Journal of cellular and molecular medicine.

VSSP abrogates murine ovarian tumor-associated myeloid cell-driven immune suppression and induces M1 polarization in tumor-associated macrophages from ovarian cancer patients

K. Odunsi, K. Eng, Kelvin P Lee, 2022, Cancer Immunology, Immunotherapy.

Mature neutrophils suppress T cell immunity in ovarian cancer microenvironment.

A. Blom, S. Ram, K. Odunsi, 2019, JCI insight.

Detachment and lysis of adherent target cells by CD4+ T cell clones involve multiple effector mechanisms.

J. Russell, S. Abrams, R. Wang, 1993, Cellular immunology.

Robust eIF4B levels undermine invasive growth and immune evasion mechanisms in murine triple negative breast cancer models

Sarah E. Walker, A. Srinivasan, S. Abrams, 2022, bioRxiv.

Target Cell Events Initiated by T-Cell Attack

J. Russell, S. Abrams, 1993 .

Induction of murine ras oncogene peptide-specific T cell responses by immunization with plasmid DNA-based minigene vectors.

S. Abrams, P. Lindinger, A. Hartl, 2003, Vaccine.

Studies on the mechanism of human natural killer cell-mediated cytolysis. I. Modulation by dexamethasone and arachidonic acid.

S. Abrams, R. Bray, Z. Brahmi, 1983, Cellular immunology.

Positive and negative consequences of soluble Fas ligand produced by an antigen-specific CD4(+) T cell response in human carcinoma immune interactions.

E. Bergmann-Leitner, S. Abrams, 2001, Cellular immunology.

Influence of interferon γ on modulation of Fas expression by human colon carcinoma cells and their subsequent sensitivity to antigen-specific CD8+ cytotoxic T lymphocyte attack

E. Bergmann-Leitner, S. Abrams, 2000, Cancer Immunology, Immunotherapy.

Lineage Differentiation Expression in T Cells To Affect Myeloid Cell IFN Regulatory Factor 8 Represses GM-CSF

M. Merad, Chen-feng Qi, K. Ozato, 2015 .

Mechanism of K562-induced human natural killer cell inactivation using highly enriched effector cells isolated via a new single-step sheep erythrocyte rosette assay.

S. Abrams, Z. Brahmi, 1988, Annales de l'Institut Pasteur. Immunology.

Strategies for the development of recombinant vaccines for the immunotherapy of breast cancer

J. Schlom, S. Abrams, J. Kantor, 2005, Breast Cancer Research and Treatment.

Cells to Fas-Mediated Apoptosis by IFN-the Sensitization of Human Colon Carcinoma Sequence-Binding Protein and Caspase-1 in Coordinate Regulation of IFN Consensus

Kebin Liu, S. Abrams, 2003 .

Target cell directed NK inactivation. Concomitant loss of NK and antibody-dependent cellular cytotoxicity activities.

S. Abrams, Z. Brahmi, 1988, Journal of immunology.

The functional loss of human natural killer cell activity induced by K562 is reversible via an interleukin-2-dependent mechanism.

S. Abrams, Z. Brahmi, 1986, Cellular immunology.

Evidence for an early calcium-independent event in the activation of the human natural killer cell cytolytic mechanism.

S. Abrams, R. Bray, Z. Brahmi, 1985, Journal of immunology.

Persistence, immune specificity, and functional ability of murine mutant ras epitope-specific CD4(+) and CD8(+) T lymphocytes following in vivo adoptive transfer.

J. Schlom, J. Bristol, S. Abrams, 1999, Cellular Immunology.

Tristetraprolin limits age-related expansion of myeloid-derived suppressor cells

P. Blackshear, K. Seldeen, S. Abrams, 2022, Frontiers in Immunology.

Immune Consequences of Protracted Host-Tumor Interactions in a Transgenic Mouse Model of Mammary Carcinoma

S. Abrams, T. Stewart, M. E. Christine Lutsiak, 2008, Cancer investigation.

Evolution of Our Understanding of Myeloid Regulatory Cells: From MDSCs to Mregs

S. Abrams, M. Manjili, Xiang-Yang Wang, 2014, Front. Immunol..

Immunogenicity and safety of a recombinant vaccinia virus vaccine expressing the carcinoembryonic antigen gene in a nonhuman primate.

J. Schlom, K. Irvine, S. Abrams, 1992, Cancer research.

Immunization with a Syngeneic Tumor Infected with Recombinant Vaccinia Virus Expressing Granulocyte‐Macrophage Colony‐Stimulating Factor (GM‐CSF) Induces Tumor Regression and Long‐Lasting Systemic Immunity

J. Schlom, S. Abrams, J. Kantor, 1997, Journal of immunotherapy.

Mitigating the prevalence and function of myeloid-derived suppressor cells by redirecting myeloid differentiation using a novel immune modulator

K. Eng, L. Carlson, S. Abrams, 2022, Journal for ImmunoTherapy of Cancer.

No Evidence That Genetic Variation in the Myeloid-Derived Suppressor Cell Pathway Influences Ovarian Cancer Survival

Lara E Sucheston-Campbell, A. Whittemore, M. Beckmann, 2016, Cancer Epidemiology, Biomarkers & Prevention.

Alterations in Fas Expression Are Characteristic of, But Not Solely Responsible for, Enhanced Metastatic Competence

Kebin Liu, S. Abrams, 2003, The Journal of Immunology.

CD4+ T lymphocyte-induced target cell detachment. A model for T cell-mediated lytic and nonlytic inflammatory processes.

J. Russell, S. Abrams, 1991, Journal of immunology.

Hypoxic activation of PFKFB4 in breast tumor microenvironment shapes metabolic and cellular plasticity to accentuate metastatic competence

W. Bshara, M. Seshadri, S. Rosario, 2022, Cell reports.

Inhibiting the biogenesis of myeloid-derived suppressor cells enhances immunotherapy efficacy against mammary tumor progression

Jennifer L. Peresie, M. Opyrchal, S. Abrams, 2022, The Journal of clinical investigation.

Adoptive immunotherapy as an in vivo model to explore antitumor mechanisms induced by a recombinant anticancer vaccine.

S. Steinberg, J. Schlom, S. Abrams, 1997, Journal of immunotherapy.

Mechanism of action of phorbol myristate acetate on human natural killer cell activity.

S. Abrams, R. Bray, Z. Brahmi, 1983, Cellular immunology.

In vivo gene inoculation of a recombinant single-chain antitumor antibody induces anti-immunoglobulin response.

J. Schlom, S. Abrams, D. Milenic, 1997, Cancer gene therapy.

β2-adrenergic receptor signaling regulates metabolic pathways critical to myeloid-derived suppressor cell function within the TME

E. Repasky, S. Abrams, P. McCarthy, 2021, Cell reports.

A2A adenosine receptor protects tumors from antitumor T cells

A. Ohta, M. Sitkovsky, Kebin Liu, 2006, Proceedings of the National Academy of Sciences.

RECOMBINANT VIRAL AND BACTERIAL VACCINES

J. Schlom, S. Abrams, D. Grosenbach, 2007 .

Cancer in primary immunodeficiency diseases: Cancer incidence in the United States Immune Deficiency Network Registry

C. Cunningham-Rundles, H. Ochs, K. Sullivan, 2017, The Journal of allergy and clinical immunology.

Developmental pathways of myeloid-derived suppressor cells in neoplasia.

S. Abrams, 2020, Cellular immunology.

Loss of amphiregulin reduces myoepithelial cell coverage of mammary ducts and alters breast tumor growth

J. Segall, P. Kenny, J. Condeelis, 2018, Breast Cancer Research.

Combination Chemotherapy and Radiation of Human Squamous Cell Carcinoma of the Head and Neck Augments CTL-Mediated Lysis

J. Schlom, J. S. Gutkind, V. Patel, 2006, Clinical Cancer Research.

CpG Immunomer DNA Enhances Antisense Protein Kinase A RIα Inhibition of Multidrug-Resistant Colon Carcinoma Growth in Nude Mice: Molecular Basis for Combinatorial Therapy

Y. Cho‐Chung, S. Abrams, M. Nesterova, 2005, Clinical Cancer Research.

Regulation of Tumor Progression by Anti-Neoplastic T Cell Responses

S. Abrams, 2004, Cancer biology & therapy.

Altered Immune Function during Long-Term Host-Tumor Interactions Can Be Modulated to Retard Autochthonous Neoplastic Growth1

S. Abrams, T. Stewart, Trina J. Stewart, 2007, The Journal of Immunology.

Tumor-Derived G-CSF Facilitates Neoplastic Growth through a Granulocytic Myeloid-Derived Suppressor Cell-Dependent Mechanism

Qiang Hu, Song Liu, Austin Miller, 2011, PloS one.

Targeting dual signalling pathways in concert with immune checkpoints for the treatment of pancreatic cancer

Jianmin Wang, M. Seshadri, E. Knudsen, 2020, Gut.

Immunization with short peptide particles reveals a functional CD8+ T-cell neoepitope in a murine renal carcinoma model

Fumito Ito, J. Ortega, M. Tsuji, 2021, Journal for ImmunoTherapy of Cancer.

Position‐Scanning Peptide Libraries as Particle Immunogens for Improving CD8+ T‐Cell Responses

Fumito Ito, J. Ortega, M. Long, 2021, Advanced science.

MMP3-Mediated tumor progression is controlled transcriptionally by a novel IRF8-MMP3 interaction

S. Abrams, P. Bogner, Colleen S Netherby, 2015, Oncotarget.

Breast Tumor Microenvironment in Black Women: A Distinct Signature of CD8+ T Cell Exhaustion.

Song Liu, S. Yao, T. Khoury, 2021, Journal of the National Cancer Institute.

Exposure of Human Primary Colon Carcinoma Cells to Anti-Fas Interactions Influences the Emergence of Pre-existing Fas-Resistant Metastatic Subpopulations

Kebin Liu, S. Abrams, E. McDuffie, 2003, The Journal of Immunology.

Coordinate Regulation of IFN Consensus Sequence-Binding Protein and Caspase-1 in the Sensitization of Human Colon Carcinoma Cells to Fas-Mediated Apoptosis by IFN-γ

Kebin Liu, S. Abrams, 2003, The Journal of Immunology.

The Curative Outcome of Radioimmunotherapy in a Mouse Breast Cancer Model Relies on mTOR Signaling

J. Neefjes, R. Johnstone, M. Verheij, 2014, Radiation research.

The Dr. Jekyll and Mr. Hyde complexity of the macrophage response in disease

S. Abrams, Lauren Burkard-Mandel, D. Twum, 2017, Journal of leukocyte biology.

How tumours escape mass destruction

S. Abrams, T. Stewart, Trina J. Stewart, 2008, Oncogene.

Discovering Myeloid Cell Heterogeneity in Mandibular Bone – Cell by Cell Analysis

S. Abrams, J. Bard, K. Kirkwood, 2021, Frontiers in Physiology.

Immunological responses can have both pro- and antitumour effects: implications for immunotherapy

S. Abrams, K. Greeneltch, T. Stewart, 2007, Expert Reviews in Molecular Medicine.

Repression of IFN regulatory factor 8 by DNA methylation is a molecular determinant of apoptotic resistance and metastatic phenotype in metastatic tumor cells.

K. Ozato, V. Ganapathy, M. Thangaraju, 2007, Cancer research.

Acquired resistance to PD-L1 inhibition is associated with an enhanced type I IFN-stimulated secretory program in tumor cells

M. Long, S. Abrams, J. Ebos, 2021, bioRxiv.

Retard Autochthonous Neoplastic Growth Host-Tumor Interactions Can Be Modulated Altered Immune Function during Long-Term

S. Abrams, T. Stewart, Trina J. Stewart, 2007 .

Fungal mycobiome drives IL-33 secretion and type 2 immunity in pancreatic cancer.

R. DePinho, Jianmin Wang, A. Maitra, 2022, Cancer cell.

Granulocytic Myeloid-Derived Suppressor Cells as Negative Regulators of Anticancer Immunity

S. Abrams, Elliot D. Kramer, 2020, Frontiers in Immunology.

Local, multimodal intralesional therapy renders distant brain metastases susceptible to PD-L1 blockade in a preclinical model of triple-negative breast cancer

Fumito Ito, S. Abrams, T. Yokoi, 2021, Scientific Reports.

Pancreatic cancer stem cells in patient pancreatic xenografts are sensitive to drozitumab, an agonistic antibody against DR5

B. Hylander, E. Repasky, J. Gibbs, 2016, Journal of Immunotherapy for Cancer.

Construction and characterization of a recombinant vaccinia virus expressing murine intercellular adhesion molecule-1: induction and potentiation of antitumor responses.

J. Schlom, S. Abrams, J. Kantor, 1997, Human gene therapy.

Blockade of p38 kinase impedes the mobilization of protumorigenic myeloid populations to impact breast cancer metastasis

P. Wallace, Andrei V Bakin, S. Abrams, 2020, International journal of cancer.

Genetic Variants in Immune-Related Pathways and Breast Cancer Risk in African American Women in the AMBER Consortium

Lara E Sucheston-Campbell, Lara E. Sucheston-Campbell, K. Lunetta, 2018, Cancer Epidemiology, Biomarkers & Prevention.

Inhibition of LSD1 in MDS Progenitors Restores Differentiation of CD141Hi Conventional Dendritic Cells

Jianmin Wang, Jennifer L. Peresie, K. Eng, 2020, Leukemia.

Mutant ras epitopes as targets for cancer vaccines.

P. Hand, J. Schlom, S. Abrams, 1996, Seminars in oncology.

IFN regulatory factor-8 expression in macrophages governs an antimetastatic program.

M. Seshadri, S. Abrams, M. Hensen, 2019, JCI insight.

CHAPTER 8 – Development of Epitope-Specific Immunotherapies for Human Malignancies and Premalignant Lesions Expressing Mutated ras Genes

S. Abrams, 2002 .

Cancer vaccine development.

J. Schlom, S. Abrams, J. Kantor, 1998, Expert opinion on investigational drugs.

Rational antigen modification as a strategy to upregulate or downregulate antigen recognition.

J. Schlom, S. Abrams, 2000, Current opinion in immunology.

Identification of a human CD8+ T lymphocyte neo-epitope created by a ras codon 12 mutation which is restricted by the HLA-A2 allele.

W. L. Shupert, J. Schlom, E. Bergmann-Leitner, 1998, Cellular immunology.

Toll-like receptor-5 agonist, entolimod, suppresses metastasis and induces immunity by stimulating an NK-dendritic-CD8+ T-cell axis

S. Gollnick, A. Gudkov, S. Abrams, 2016, Proceedings of the National Academy of Sciences.

Cooperative disengagement of Fas and intercellular adhesion molecule-1 function in neoplastic cells confers enhanced colonization efficiency.

Kebin Liu, S. Abrams, Sheila A. Caldwell, 2005, Cancer research.

Development of a murine mutant Ras CD8+ CTL peptide epitope variant that possesses enhanced MHC class I binding and immunogenic properties.

J. Schlom, J. Bristol, S. Abrams, 1998, Journal of immunology.

Multimodal Intralesional Therapy for Reshaping the Myeloid Compartment of Tumors Resistant to Anti–PD-L1 Therapy via IRF8 Expression

Fumito Ito, S. Abrams, T. Yokoi, 2021, The Journal of Immunology.

A Pilot Study of Stereotactic Body Radiation Therapy Combined with Cytoreductive Nephrectomy for Metastatic Renal Cell Carcinoma

Anurag K. Singh, W. Bshara, G. Warren, 2017, Clinical Cancer Research.

Stromal remodeling regulates dendritic cell abundance and activity in the tumor microenvironment

O. Harismendy, K. Politi, D. Deming, 2021, bioRxiv.

Total cellular protein presence of the transcription factor IRF8 does not necessarily correlate with its nuclear presence.

P. Wallace, S. Abrams, O. Maguire, 2017, Methods.

Enhanced immune responses and anti-tumor activity by baculovirus recombinant carcinoembryonic antigen (CEA) in mice primed with the recombinant vaccinia CEA.

J. Schlom, S. Abrams, S. Kashmiri, 1994, Journal of immunotherapy with emphasis on tumor immunology : official journal of the Society for Biological Therapy.

Downregulation of IFN‐γR in association with loss of Fas function is linked to tumor progression

Dafeng Yang, Kebin Liu, S. Abrams, 2008, International journal of cancer.

Immune selection and emergence of aggressive tumor variants as negative consequences of Fas-mediated cytotoxicity and altered IFN-gamma-regulated gene expression.

Kebin Liu, S. Abrams, Sheila A. Caldwell, 2005, Cancer research.

Regression of Extensive Pulmonary Metastases in Mice by Adoptive Transfer of Antigen-Specific CD8+ CTL Reactive Against Tumor Cells Expressing a Naturally Occurring Rejection Epitope

M. H. Ryan, J. Bristol, S. Abrams, 2001, The Journal of Immunology.

Occurring Rejection Epitope Tumor Cells Expressing a Naturally CTL Reactive Against + Antigen-Specific CD8 Metastases in Mice by Adoptive Transfer of Regression of Extensive Pulmonary

M. H. Ryan, J. Bristol, S. Abrams, 2001 .

Tumor-induced MDSC act via remote control to inhibit L-selectin-dependent adaptive immunity in lymph nodes

Daniel T. Fisher, Minhyung Kim, S. Abrams, 2016, eLife.

Specific Immunotherapy Using a Recombinant Vaccinia Virus Expressing Human Carcinoembryonic Antigen

J. Schlom, K. Irvine, S. Abrams, 1993, Annals of the New York Academy of Sciences.

β2 Adrenergic receptor-mediated signaling regulates the immunosuppressive potential of myeloid-derived suppressor cells.

B. Hylander, E. Repasky, S. Abrams, 2019, The Journal of clinical investigation.

Identification of monocyte-like precursors of granulocytes in cancer as a mechanism for accumulation of PMN-MDSCs

George A. Dominguez, Joseph Bennett, L. Languino, 2019, The Journal of experimental medicine.

Inhibition of Casein Kinase 2 Disrupts Differentiation of Myeloid Cells in Cancer and Enhances the Efficacy of Immunotherapy in Mice.

J. Hunt, A. Kossenkov, S. Abrams, 2018, Cancer research.

Interferon Regulatory Factor-8 Is Important for Histone Deacetylase Inhibitor-Mediated Antitumor Activity

S. Abrams, E. Walseng, B. Segal, 2012, PloS one.

A multi-functional role of interferon regulatory factor-8 in solid tumor and myeloid cell biology

S. Abrams, 2010, Immunologic research.

Signaling through TLR5 mitigates lethal radiation damage by neutrophil-dependent release of MMP-9

A. Gudkov, S. Abrams, Bojidar M Kandar, 2021, Cell death discovery.

Inhibition of platelet GPVI induces intratumor hemorrhage and increases efficacy of chemotherapy in mice.

A. Zernecke, B. Nieswandt, S. Ergün, 2019, Blood.

Platelet integrin α6β1 controls lung metastasis through direct binding to cancer cell-derived ADAM9.

M. Freund, S. Abrams, C. Gachet, 2016, JCI insight.

Case Study in International Cooperation: Cuba's Molecular Immunology Center and Roswell Park Cancer Institute.

Kelvin P Lee, S. Abrams, M. Reid, 2018, MEDICC review.

A Potent Cancer Vaccine Adjuvant System for Particleization of Short, Synthetic CD8+ T Cell Epitopes.

J. Ortega, S. Abrams, J. Lovell, 2021, ACS nano.

b-Adrenergic Signaling in Mice Housed at Standard Temperatures Suppresses an Effector Phenotype in CD8þ T Cells and Undermines Checkpoint Inhibitor Therapy

B. Hylander, E. Repasky, K. Attwood, 2017 .

1 β-adrenergic signaling in mice housed at standard temperatures suppresses an effector phenotype in CD 8 + T cells and undermines checkpoint inhibitor therapy Running Title : β-blockers increase T cell effectors and anti-PD-1 efficacy

B. Hylander, E. Repasky, K. Attwood, 2017 .

Radiation induces dynamic changes to the T cell repertoire in renal cell carcinoma patients

Anurag K. Singh, S. Abrams, J. Muhitch, 2020, Proceedings of the National Academy of Sciences.

Role of anti-CTLA-4 therapies in the treatment of cancer.

S. Abrams, 2004, Current opinion in molecular therapeutics.

Tasquinimod Modulates Suppressive Myeloid Cells and Enhances Cancer Immunotherapies in Murine Models

L. Ellis, T. Leanderson, S. Ramakrishnan, 2014, Cancer Immunology Research.

Targeting dual signaling pathways in concert with immune checkpoints for the treatment of pancreatic cancer

Jianmin Wang, M. Seshadri, E. Knudsen, 2019, bioRxiv.

Tumor-associated macrophage expression of interferon regulatory Factor-8 (IRF8) is a predictor of progression and patient survival in renal cell carcinoma

C. Morrison, W. Bshara, Austin Miller, 2019, Journal of Immunotherapy for Cancer.

The economics of alternative fuel reduction treatments in western United States dry forests: Financial and policy implications from the National Fire and Fire Surrogate Study

Bruce R. Hartsough, Scott L. Stephens, R. James Barbour, 2008 .

Abstract 3226: The IRF8-osteopontin-CD44 axis functions as an immune checkpoint to control CD8+ T cell activation and tumor immune evasion

K. Ozato, Dafeng Yang, Kebin Liu, 2019, Immunology.

Strategies in the development of recombinant vaccines for colon cancer.

J. Schlom, S. Abrams, J. Kantor, 1999, Seminars in oncology.

b2 adrenergic receptor–mediated signaling regulates the immunosuppressive potential of myeloid-derived suppressor cells

B. Hylander, E. Repasky, S. Abrams, 2019 .

Treatment of human colon carcinoma cell lines with anti-neoplastic agents enhances their lytic sensitivity to antigen-specific CD8+ cytotoxic T lymphocytes

E. Bergmann-Leitner, S. Abrams, 2001, Cancer Immunology, Immunotherapy.

Targeting Lymphotoxin β Receptor with Tumor-Specific T Lymphocytes for Tumor Regression

Dafeng Yang, Kebin Liu, S. Abrams, 2007, Clinical Cancer Research.

β-Catenin signaling in alveolar macrophages enhances lung metastasis through a TNF-dependent mechanism

M. Taketo, S. Abrams, C. Brackett, 2023, JCI insight.

Compared mechanisms of tumor cytolysis by human natural killer cells and activated polymorphonuclear leukocytes.

S. Abrams, Z. Brahmi, 1984, Journal of immunology.

HPV-Associated Tumor Eradication by Vaccination with Synthetic Short Peptides and Particle-Forming Liposomes.

J. Ortega, S. Abrams, J. Lovell, 2021, Small.

Tumor and immune remodeling following radiotherapy in human renal cell carcinoma

Ashutosh Kumar Singh, P. Wallace, E. Repasky, 2023, Journal for ImmunoTherapy of Cancer.

Separation of CD4+ functional responses by peptide dose in Th1 and Th2 subsets expressing the same transgenic antigen receptor.

C. Hsieh, K. Murphy, D. Loh, 1993, Cellular immunology.

Apoptosis, growth arrest and suppression of invasiveness by CRE-decoy oligonucleotide in ovarian cancer cells: Protein kinase A downregulation and cytoplasmic export of CRE-binding proteins

Y. Cho‐Chung, E. Bergmann-Leitner, S. Abrams, 2001, Molecular and Cellular Biochemistry.

BiTE secretion by adoptively transferred stem-like T cells improves FRα+ ovarian cancer control

K. Odunsi, S. Rosario, M. Long, 2023, Journal for ImmunoTherapy of Cancer.

Editorial: The rebirth of myeloid‐derived suppressor cells: from adversary in cancer to ally in reproductive health

S. Abrams, 2017, Journal of leukocyte biology.

Mature neutrophils suppress T cell immunity in ovarian cancer microenvironment.

A. Blom, S. Ram, K. Odunsi, 2019, JCI insight.

S. Abrams, J. Waight, 2012 .

This information is current as Experimental CMS 4 Lung Metastases Model of CTL Adoptive Immunotherapy of for Optimal Tumor Regression in a Mouse The Fas / Fas Ligand Pathway Is Important

M. H. Ryan, S. Abrams, Sheila A. Caldwell, 2003 .

Phase Ib/II Study of Cetuximab plus Pembrolizumab in Patients with Advanced RAS Wild-Type Colorectal Cancer

A. Hutson, E. Knudsen, A. Witkiewicz, 2021, Clinical Cancer Research.

Tumor-induced MDSC act via remote control to inhibit L-selectin-dependent adaptive immunity in lymph nodes

Minhyung Kim, S. Abrams, J. Skitzki, 2016, eLife.

Mitigating the prevalence and function of myeloid-derived suppressor cells by redirecting myeloid differentiation using a novel immune modulator

K. Eng, L. Carlson, S. Abrams, 2015, Journal for ImmunoTherapy of Cancer.